Scholler
Gordon Scott Scholler, Providence, RI US
Patent application number | Description | Published |
---|---|---|
20160132476 | GUIDANCE CONTENT DEVELOPMENT AND PRESENTATION - An adaptive content system may include a storage system, a development module, and a presentation module. The storage system may store populated and unpopulated content units configured to contain information content and at least one sequence link selectable by a user for establishing a sequence in which the content units are presented to a user. The development module may populate or modify a stored content unit. The presentation module may access the storage system to retrieve content units for presentation on an output device in response to inputs received from an input device without allowing modification of the information content populated on the content units. | 05-12-2016 |
20160134741 | USER-DIRECTED INFORMATION CONTENT - A content-presenting apparatus may include an output device configured to output to a user content of a content unit in a form sensible to a user. A storage device may store a collection of interrelated content units having a sequence link to at least one other content unit. A plurality of the content units may have sequence links to at least three other content units. A sequence link may be to a content unit that does not have a sequence link back to the same content unit. A processor may be configured to output on the at least one output device content units sequentially in response to inputs received from the user on at least one input device, receive on the at least one input device an indication input by the user that correlates to a sequence link back to a content unit not having a reciprocal sequence link. | 05-12-2016 |
Gordon Scott Scholler, Poway, CA US
Patent application number | Description | Published |
---|---|---|
20110306026 | SYSTEM FOR MAKING AND VIEWING AUDIO-VISUAL INSTRUCTIONAL CONTENT - An instructive content creation and viewing system, including a first microprocessor assembly, an intuitive viewing interface, a second microprocessor assembly in communication with the first microprocessor assembly, and an content creation interface. The viewing interface is housed on the first microprocessor assembly and the content creation interface is housed on the second microprocessor assembly. The content creation interface is used to create the instructive content, while the first microprocessor assembly obtains the instructive content. The viewing interface presents the instructive content while the viewing interface adapts to the instructive content and user preferences or actions. | 12-15-2011 |
20110306030 | METHOD FOR RETAINING, MANAGING AND INTERACTIVELY CONVEYING KNOWLEDGE AND INSTRUCTIONAL CONTENT - An instructive content creation and viewing system, including a first microprocessor assembly, an intuitive viewing interface, a second microprocessor assembly in communication with the first microprocessor assembly, and an content creation interface. The viewing interface is housed on the first microprocessor assembly and the content creation interface is housed on the second microprocessor assembly. The content creation interface is used to create the instructive content, while the first microprocessor assembly obtains the instructive content. The viewing interface presents the instructive content while the viewing interface adapts to the instructive content and user preferences or actions. | 12-15-2011 |
20110307779 | SYSTEM OF RETAINING, MANAGING AND INTERACTIVELY CONVEYING KNOWLEDGE AND INSTRUCTIONAL CONTENT - An instructive content creation and viewing system, including a first microprocessor assembly, an intuitive viewing interface, a second microprocessor assembly in communication with the first microprocessor assembly, and an content creation interface. The viewing interface is housed on the first microprocessor assembly and the content creation interface is housed on the second microprocessor assembly. The content creation interface is used to create the instructive content, while the first microprocessor assembly obtains the instructive content. The viewing interface presents the instructive content while the viewing interface adapts to the instructive content and user preferences or actions. | 12-15-2011 |
G. Scott Scholler, Poway, CA US
Patent application number | Description | Published |
---|---|---|
20130006562 | QUALITY ASSURANCE SYSTEM FOR ELECTIONS - A system is provided for improved quality assurance (QA) in remote-access elections by a QA unit that evaluates an election service provider (ESP) that tallies votes, each of which includes a vote-identification number (VIN) and a vote content. The QA unit assures a likelihood that no votes have been deleted, inserted or changed by the ESP. The QA unit does this by allocating QA VINs and voting QA votes and then checking the ESP's report of all VINs included in the tally and the content of all QA votes. The ESP, if unaware of which votes are QA votes and which are voter voters, is prevented from deleting, inserting, or changing votes without risk of detection by the check of the QA votes. The system includes capability of ensuring defined confidence levels for a given quantity of voters and an expected voter turnout by incorporation of a suitable number of QA VINs. | 01-03-2013 |
James Scholler, Brookfield, WI US
Patent application number | Description | Published |
---|---|---|
20130134017 | Conveyor Drive With Integrated Controller - A drive unit for a roller conveyor assembly having a motor and an integrated motor controller. The controller is mounted on a circuit board and connected to the rear of the motor housing. A cover for the controller substantially encloses the controller. An opening in the cover allows access to a terminal block from the controller. The terminal block receives wiring to external devices and to other zone controllers. Wiring between the circuit board for the controller and the motor is performed as a step in the assembly of the integrated motor and controller. The motor and controller are configured to be mounted below the rollers and between the side frames of a conveyor assembly. An output shaft from the motor is coupled to the rollers to power the conveyor assembly. | 05-30-2013 |
20140129026 | Multi-Zone Conveyor System Having LAN Based Control - A control system for a conveyor system having one or more upstream and downstream conveyor zones and whose operation effectuates transportation of a series of loads via operation of motors and drive arrangements associated with the respective conveyor zones. The control system includes a Local Area Network (LAN) connection between each component of the control arrangement associated with each zone control such that status and operational information associated with the configuration or operation of each conveyor zone, including the zone motor, can be communicated to other conveyor zones so that operation of each conveyor zone can be manipulated in a controlled manner in response to changes to operation of other conveyor zones. | 05-08-2014 |
Jerome Scholler, San Francisco, CA US
Patent application number | Description | Published |
---|---|---|
20150339532 | Virtualization of Tangible Interface Objects - An example system includes a stand configured to position a computing device proximate to a physical activity surface. The system further includes a video capture device, a detector, and an activity application. The video capture device is coupled for communication with the computing device and is adapted to capture a video stream that includes an activity scene of the physical activity surface and one or more interface objects physically interactable with by a user. The detector is executable to detect motion in the activity scene based on the processing and, responsive to detecting the motion, process the video stream to detect one or more interface objects included in the activity scene of the physical activity surface. The activity application is executable to present virtual information on a display of the computing device based on the one or more detected interface objects. | 11-26-2015 |
Jerome F. Scholler, San Francisco, CA US
Patent application number | Description | Published |
---|---|---|
20140111523 | VARIABLE LENGTH ANIMATIONS BASED ON USER INPUTS - A computer-implemented method for transition animation is disclosed according to one aspect of the subject technology. The method comprises determining a user's level of experience using an application, determining a duration of a transition animation based on the user's determined level of experience, and playing the transition animation for the determined duration. | 04-24-2014 |
20150199082 | DISPLAYING ACTIONABLE ITEMS IN AN OVERSCROLL AREA - Systems and methods for user interface management are provided. In some aspects, a first scroll beyond an original content being presented for a user is detected, where the first scroll indicates an overscroll event. Menu content is provided for display upon detection of the first scroll, where the menu content includes one or more actionable items. | 07-16-2015 |
20150205473 | SYSTEMS AND METHODS FOR VISUALLY SCROLLING THROUGH A STACK OF ITEMS DISPLAYED ON A DEVICE - Systems and methods for visually scrolling through a stack of items displayed on a device are provided. In some aspects, a system includes a detection module configured to determine a motion of the device relative to a neutral position of the device. The system also includes a display module configured to visually scroll through the stack of items in response to the motion of the device. | 07-23-2015 |
20150206510 | SYSTEMS AND METHODS FOR VISUALLY SCROLLING THROUGH A STACK OF ITEMS DISPLAYED ON A DEVICE - Computer-implemented methods for visually scrolling through a stack of items displayed on a device by tilting the device are provided. In one aspect, a method includes determining a neutral reference point for a device, and receiving input indicating a tilting motion from the neutral reference point encountered by the device. The method also includes determining an angular displacement value of the device and a bias factor based on the tilting motion. The angular displacement value is indicative of an angular displacement of the device based on the tilting motion. The method also includes visually scrolling through the stack of items based on the angular displacement value and the bias factor. Systems and machine-readable media are also provided. | 07-23-2015 |
John Scholler, Penn Valley, PA US
Patent application number | Description | Published |
---|---|---|
20140099340 | Compositions and Methods for Targeting Stromal Cells for the Treatment of Cancer - The present invention provides compositions and methods for treating cancer in a human. The invention relates to targeting the stromal cell population in a tumor microenvironment. For example, in one embodiment, the invention provides a composition that is targeted to fibroblast activation protein (FAP). The invention includes a chimeric antigen receptor (CAR) which comprises an anti-FAP domain, a transmembrane domain, and a CD3zeta signaling domain. | 04-10-2014 |
John Scholler, Narberth, PA US
Patent application number | Description | Published |
---|---|---|
20140271635 | TREATMENT OF CANCER USING HUMANIZED ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR - The invention provides compositions and methods for treating diseases associated with expression of CD19. The invention also relates to chimeric antigen receptor (CAR) specific to CD19, vectors encoding the same, and recombinant T cells comprising the CD19 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD19 binding domain. | 09-18-2014 |
20140322212 | EFFECTIVE TARGETING OF PRIMARY HUMAN LEUKEMIA USING ANTI-CD123 CHIMERIC ANTIGEN RECEPTOR ENGINEERED T CELLS - The invention provides compositions and methods for treating leukemia, for example, acute myeloid leukemia (AML) and B-cell acute lymphoid leukemia (B-ALL). The invention also relates to at least one chimeric antigen receptor (CAR) specific to CD123, vectors comprising the same, and recombinant T cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD123 binding domain. The invention also includes methods of bone marrow ablation for use in treatments necessitating bone marrow reconditioning or transplant. | 10-30-2014 |
20140322275 | TREATMENT OF CANCER USING HUMANIZED ANTI-EGFRvIII CHIMERIC ANTIGEN RECEPTOR - The invention provides compositions and methods for treating diseases associated with expression of EGFRvIII. The invention also relates to chimeric antigen receptor (CAR) specific to EGFRvIII, vectors encoding the same, and recombinant T cells comprising the anti-EGFRvIII CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an anti-EGFRvIII binding domain. | 10-30-2014 |
20140370045 | USE OF THE CD2 SIGNALING DOMAIN IN SECOND-GENERATION CHIMERIC ANTIGEN RECEPTORS - The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell expressing a CAR having an antigen binding domain, a transmembrane domain, a CD2 signaling domain, and a CD3 zeta signaling domain. The invention also includes incorporating CD2 into the CAR to alter the cytokine production of CAR-T cells in both negative and positive directions. | 12-18-2014 |
20150017141 | USE OF ICOS-BASED CARS TO ENHANCE ANTITUMOR ACTIVITY AND CAR PERSISTENCE - The present invention provides compositions and methods for treating cancer in a human. The invention includes administering a genetically modified Th17 cell to express a CAR having an antigen binding domain, a transmembrane domain, and an ICOS intracellular signaling domain. | 01-15-2015 |
20150024482 | Compositions and Methods for Generating a Persisting Population of T Cells Useful for the Treatment of Cancer - The present invention provides compositions and methods for generating a genetically modified T cells comprising a chimeric antigen receptor (CAR) having an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain, wherein the T cell exhibits prolonged exponential expansion in culture that is ligand independent and independent of the addition of exogenous cytokines or feeder cells. | 01-22-2015 |
Jorgen Scholler, Lyngby DK
Patent application number | Description | Published |
---|---|---|
20100168390 | MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE - The present invention describes novel methods to generate MHC multimers and methods to improve existing and new MHC multimers. The invention also describes improved methods for the use of MHC multimers in analysis of T-cells in samples including diagnostic and prognostic methods. Furthermore the use of MHC multimers in therapy are described, e.g. anti-tumour and anti-virus therapy, including isolation of antigen specific T-cells capable of inactivation or elimination of undesirable targeT-cells or isolation of specific T-cells capable of regulation of other immune cells. | 07-01-2010 |
Jørgen Scholler, Lyngby DK
Patent application number | Description | Published |
---|---|---|
20110236411 | MHC Multimers in Tuberculosis Diagnostics, Vaccine and Therapeutics - The present invention relates to MHC-peptide complexes and uses thereof in the diagnosis of, treatment of or vaccination against a disease in an individual. More specifically the invention discloses MHC complexes comprising | 09-29-2011 |
Klaus Scholler, Eindhoven NL
Patent application number | Description | Published |
---|---|---|
20100045197 | GAS-DISCHARGE LAMP - A gas-discharge lamp ( | 02-25-2010 |
Marek Scholler, Brno CZ
Patent application number | Description | Published |
---|---|---|
20160025334 | OXYGEN-FUEL BURNER WITH STAGED OXYGEN SUPPLY - A nozzle in a burner assembly is configured to produce a flame. The nozzle is configured to include a fuel-discharge outlet and to conduct fuel along a path in the nozzle to the fuel-discharge outlet. Pressurized primary oxygen is provided to mix with fuel discharged by the nozzle to produce a mixture that can be ignited to produce a flame. Staged oxygen is provided to the flame in a region downstream from the nozzle. | 01-28-2016 |
Nathalie Scholler, Penn Valley, PA US
Patent application number | Description | Published |
---|---|---|
20120294799 | ANTI-TEM1 ANTIBODIES AND USES THEREOF - The invention relates to Anti-TEM 1 anti-bodies or antigen-binding fragments thereof, yeast libraries comprising the same, and prophylactic, diagnostic, and therapeutic methods using the same. | 11-22-2012 |
Nathalie Scholler, Seattle, WA US
Patent application number | Description | Published |
---|---|---|
20100150925 | TREATMENT OF B-CELL CANCERS WITH ANTI-CD70 ANTIBODY-DRUG CONJUGATES - Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of a CD70-expressing cancer, comprising administering to a subject the disclosed pharmaceutical compositions. | 06-17-2010 |
20100158910 | TREATMENT OF RENAL CELL CARCINOMA WITH ANTI-CD70 ANTIBODY-DRUG CONJUGATES - Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing a cancer, comprising administering to a subject the disclosed pharmaceutical compositions. | 06-24-2010 |
20100183636 | ANTI-CD70 ANTIBODY-DRUG CONJUGATES AND THEIR USE FOR THE TREATMENT OF CANCER AND IMMUNE DISORDERS - Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions. | 07-22-2010 |
20120251559 | Treatment of B-Cell Cancers With Anti-CD70 Antibody-Drug Conjugates - Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of a CD70-expressing cancer, comprising administering to a subject the disclosed pharmaceutical compositions. | 10-04-2012 |
20120288512 | Anti-CD70 Antibody-Drug Conjugates and Their Use for the Treatment of Cancer and Immune Disorders - Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions. | 11-15-2012 |
Nathalie Scholler, Mountain View, CA US
Patent application number | Description | Published |
---|---|---|
20140294861 | ISOLATED B7-H4 SPECIFIC COMPOSITIONS AND METHODS OF USE THEREOF - The present invention relates to B7-H4-specific compositions and methods of use thereof. | 10-02-2014 |
20140301993 | FULLY HUMAN, ANTI-MESOTHELIN SPECIFIC CHIMERIC IMMUNE RECEPTOR FOR REDIRECTED MESOTHELIN-EXPRESSING CELL TARGETING - The present invention relates to compositions and methods for treating diseases, disorders or conditions associated with dysregulated expression of mesothelin. In one embodiment, the invention relates to a fully human chimeric antigen receptor (CAR) wherein the CAR is able to target mesothelin. | 10-09-2014 |
20140308259 | ISOLATED B7-H4 SPECIFIC COMPOSITIONS AND METHODS OF USE THEREOF - The present invention relates to B7-H4-specific chimeric antigen receptor compositions and methods of use thereof. | 10-16-2014 |
Nathalie Scholler, Narberth, PA US
Patent application number | Description | Published |
---|---|---|
20110104675 | Methods and Compositions for Diagnosing Carcinomas - The invention is directed to compositions and methods for the detection of a malignant condition, and relates to the discovery of soluble forms of mesothelin polypeptides, including mesothelin related antigen (MRA). In particular the invention provides a nucleic acid sequence encoding MRA and an MRA variant. The invention also provides a method of screening for the presence of a malignant condition in a subject by detecting reactivity of an antibody specific for a mesothelin polypeptide with a molecule naturally occurring in soluble form in a sample from such a subject, and by hybridization screening using an MRA nucleotide sequence, as well as other related advantages. | 05-05-2011 |
20140234348 | Universal Immune Receptor Expressed by T Cells for the Targeting of Diverse and Multiple Antigens - The invention provides compositions and methods for adoptive T cell therapy in treating a variety of disorders including cancer, infections, and autoimmune disorders. In one embodiment, the invention provides a universal immune receptor (UnivIR) that comprises an extracellular label binding domain, a transmembrane domain, and a cytoplasmic domain or otherwise an intracellular domain. | 08-21-2014 |