Schoenen
Frank Schoenen, Wurzburg DE
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20100322936 | LM-1 ANTIBODIES, FUNCTIONAL FRAGMENTS, LM-1 TARGET ANTIGEN, AND METHODS FOR MAKING AND USING SAME - The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject. | 12-23-2010 |
20150071931 | LM-Antibodies, Functional Fragments, LM-1 Target Antigen, and Methods for Making and Using Same - The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject. | 03-12-2015 |
Frank Schoenen, Lawrence, KS US
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20140371194 | METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS - This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis. | 12-18-2014 |
20150031658 | ETHOXYPHENYL THIENYL COMPOUNDS AND METHODS FOR THE TREATMENT OFBACTERIAL INFECTIONS - This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis. | 01-29-2015 |
Frank J. Schoenen, Laurence, KS US
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20090264384 | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF - Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 10-22-2009 |
Frank J. Schoenen, Lawrence, KS US
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20080269204 | Compounds and Methods of Use Thereof - Benzolactam boronic acid compounds and pharmaceutical formulations are described along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 10-30-2008 |
20080319044 | Compounds and Methods of Use Thereof - Indole boronic acid compounds, and analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 12-25-2008 |
20090005344 | Compounds and Methods of Use Thereof - Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 01-01-2009 |
20090170842 | BRCA1-BASED BREAST OR OVARIAN CANCER PREVENTION AGENTS AND METHODS OF USE - A pharmaceutical composition for use in treating, inhibiting, and/or preventing breast and/or ovarian cancer can include: a molecule having a structure of one of Compounds 1-38, pharmaceutically acceptable salt thereof, or analog thereof, and a pharmaceutically acceptable carrier containing the compound. The pharmaceutically acceptable carrier can be configured for oral, systemic, transdermal, intranasal, suppository, parenteral, intramuscular, intravenous, or subcutaneous administration. The compound can be present in the composition in a therapeutically effective amount for treating, inhibiting, and/or preventing breast and/or ovarian cancer. Also, the compound can be present in a therapeutically effective amount for enhancing production of BRCA1. | 07-02-2009 |
20110288082 | METHODS AND COMPOSITIONS FOR INHIBITION OF THE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE - Compounds of Formulas I-XLIII are identified as direct inhibitors of p97 ATPase or of the degradation of a p97-dependent ubiquitin-proteasome system (UPS) substrate. Methods and compositions are disclosed for inhibiting p97 ATPase and the degradation of a p97-dependent UPS substrate, and for identifying inhibitors thereof | 11-24-2011 |
20120259005 | BRCA1-Based Breast or Ovarian Cancer Prevention Agents and Methods of Use - A pharmaceutical composition for use in treating, inhibiting, and/or preventing breast and/or ovarian cancer can include: a molecule having a structure of one of Compounds 1-38, pharmaceutically acceptable salt thereof, or analog thereof; and a pharmaceutically acceptable carrier containing the compound. The pharmaceutically acceptable carrier can be configured for oral, systemic, transdermal, intranasal, suppository, parenteral, intramuscular, intravenous, or subcutaneous administration. The compound can be present in the composition in a therapeutically effective amount for treating, inhibiting, and/or preventing breast and/or ovarian cancer. Also, the compound can be present in a therapeutically effective amount for enhancing production of BRCA1. | 10-11-2012 |
20130331018 | Laboratory Fume Hood System Having Recessed Heat Exchanger System - A laboratory fume hood system for cooling at least one laboratory device located in an interior work area comprises a heat exchanger system having a heat exchanger in thermal communication with a primary fluid loop containing chilled fluid and a secondary fluid loop containing a cooling fluid which is in thermal communication the laboratory device. The primary fluid loop is located behind the fume hood wall and not in the interior work area. | 12-12-2013 |
20140323438 | COMPOUNDS AND METHODS FOR THE PREVENTION AND TREATMENT OF TUMOR METASTASIS AND TUMORIGENESIS - The disclosure provides compounds for reducing the prevalence of the perinucleolar compartment in cells, for example, of formula (I), wherein R | 10-30-2014 |
Frank John Schoenen, Lawrence, KS US
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20100317100 | Compositions and methods for establishing and maintaining stem cells in an undifferentiated state - The present invention embraces compositions and methods for establishing and maintaining stem cells and inhibiting stem cell differentiation using a selective Protein Kinase C (PKC) inhibitor. | 12-16-2010 |
20120270313 | Compositions and Methods for Establishing and Maintaining Stem Cells in an Undiffferentiated State - The present invention embraces compositions and methods for establishing and maintaining stem cells and inhibiting stem cell differentiation using a selective Protein Kinase C (PKC) inhibitor. | 10-25-2012 |
20150065469 | SALICYLIC ACID DERIVATIVES USEFUL AS GLUCOCEREBROSIDASE ACTIVATORS - Compounds of Formula (I) and the pharmaceutically acceptable salts thereof are disclosed. The variables. R | 03-05-2015 |
20150322087 | CEPHALOSPORIN DERIVATIVES AND METHODS OF USE - This invention provides cephalosporin derivatives for killing or inhibiting the spread of microorganisms such as non-replicating | 11-12-2015 |
Rainer Schoenen, Hamburg DE
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20160050588 | System and Method for Wireless Load Balancing - In one embodiment, a method of wireless load balancing includes receiving, by a communications controller from a device, a plurality of messages including a plurality of demands of a plurality of UEs and a plurality of locations of the plurality of UEs, where the plurality of demands includes a demand of a UE of the plurality of UEs, where the plurality of locations includes a location of the first UE, and where the location of the UE is in a cell and determining a utility map in accordance with the plurality of demands and the plurality of locations. The method also includes determining a recommendation of user behavior of a user of the first UE in accordance with the utility map, the location of the first UE, and the demand of the UE and transmitting, by the communications controller to the UE, the recommendation of user behavior. | 02-18-2016 |
Rainer Schoenen, Ottawa CA
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20130095872 | INTER-CELL INTERFERENCE COORDINATION FOR WIRELESS COMMUNICATION SYSTEMS - For each base station, transmit power level variables (I values) for each resource block allocated by the base station are initialized. The I values are used in a model to find sub-gradients for each base station. Neighboring base stations exchange the sub-gradients. For each base station, the base station's sub-gradient and the base station's neighbors' sub-gradients are used in the model to update the I values. Neighboring base stations then exchange the updated I values. For each base station, the base station's updated I value and the base station's neighbors' updated I values are used in the model to update the initial sub-gradients. The updated sub-gradients are then exchanged and used for another update of the I values. After a number of iterations, the I values are used to establish a transmit power level per resource block. | 04-18-2013 |
20140195394 | System and Method for Charging Services Using Effective Quanta Units - Embodiments are provided for enabling dynamic pricing of services to users. The amount of usage all or different services are quantized into quanta of minimum usage units, such as to an amount of effective bits (eBits) in communications services. The amount of usage of the different services is weighted differently, such as according to service cost or demand, to obtain corresponding amount of quanta of usage or eBits for each service. The amount of quanta of usage or eBits for the different services is summed up to provide a total amount of quanta of usage or eBits. The total amount of quanta of usage or eBits is converted into a total charge, as a product of the total amount of quanta of usage or eBits, or a monotonic function of the total amount, and a fixed charge rate per quanta of usage or eBit. | 07-10-2014 |
Stefan Schoenen, Jaderberg DE
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20130210160 | METHOD AND DEVICE FOR DETECTING HYDROGEN - The invention relates to a device and to a method for the detection of hydrogen in a gas mixture, wherein the device comprises a catalyst unit which is connected to a source and a supply device for CO and/or CO | 08-15-2013 |