Patent application number | Description | Published |
20110123617 | CLIOQUINOL FOR THE TREATMENT OF HEMATOLOGICAL MALIGNANCIES - The present invention relates to compositions and methods for treating hematological malignancies and proliferative diseases, disorders and conditions involving increased D-cyclin expression. In particular, the present invention relates to compositions and methods for treating the hematological malignancies acute myeloid leukemia (AML) and multiple myeloma (MM) using clioquinol. | 05-26-2011 |
20110144155 | 8-HYDROXYQUINOLINE DERIVATIVES FOR THE TREATMENT OF HEMATOLOGICAL MALIGNANCIES - The application relates to compositions and methods for treating hematological malignancies and proliferative diseases, disorders and conditions involving increased D-cyclin expression. In particular, the application relates to compositions and methods for treating the hematological malignancies acute myeloid leukemia (AML), lymphoma and multiple myeloma (MM) using 5-nitrogen substituted hydroxy quinolones as well as 7-bromo-5-chloro substituted hydroxy quinolones and 5-chloro substituted hydroxy quinolones. | 06-16-2011 |
20110212176 | CICLOPIROX AND CYTARABINE FOR THE TREATMENT OF LEUKEMIC DISORDERS - The present application relates to compositions and methods for treating leukemic disorders. In particular, the present application relates to compositions and methods for treating the leukemic disorders such as acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) using ciclopirox and cytarabine. | 09-01-2011 |
20110319427 | USE OF 5AHQ AND BORTEZOMIB FOR THE TREATMENT OF HEMATOLOGICAL DISEASES - The disclosure provides methods and compositions for treating hematological malignancies. In particular, the disclosure provides methods and compositions for treating leukemia, lymphoma and multiple myeloma using bortezomit and 5AHQ (5-ammo-8-hydroxyqumolme) and related compounds that bind non-competitively to an alpha unit of 2OS proteasome and inhibit proteasome activity Kits and commercial packages are also disclosed | 12-29-2011 |
20120329761 | USE OF TIGECYCLINE FOR TREATMENT OF CANCER - Cancer stem cells exhibit different metabolic profiles from other cancer cells, such that they do not readily respond to treatment using conventional chemotherapeutic agents. Studies disclosed herein now demonstrate that the glycylcycline antibiotic tigecycline (a tetracycline derivative) exhibits anti-cancer activity, including activity against cancer stem cells. This anti-neoplastic activity appears to be due to inhibition of mitochondrial protein synthesis in the cancer cells. In preferred embodiments, the cancer to be treated is a hematological cancer, such as leukemia, lymphoma or myeloma. | 12-27-2012 |
20140221301 | COMBINATION TREATMENT FOR CANCER - A method of treating a cancer comprising administering to a subject in need thereof an effective amount of a glycylcycline, for example tigecycline in combination with a chemotherapeutic such as daunorubicin or cytarabine. | 08-07-2014 |
Patent application number | Description | Published |
20090031152 | METHOD FOR STARTING UP AT LEAST ONE FIELD DEVICE - Disclosed is a method for starting up of at least one first field instrument, wherein the method comprises the step of signaling a firs demand for electrical power output of the first field instrument over a first port to a supply unit. According to this method, the first field instrument is previously connected to the supply unit over the first port by means of a first communication connection. In addition, the reception of the power output is effected according to the first demand for power output by the first field instrument over the first communication connection and the first port, by which the first filed instrument is activated. In an additional step, a power usage unit of the first field instrument is assigned to the first port, wherein the power usage unit is provided as consumer load for the power output. | 01-29-2009 |
20130264472 | MEASURING TRANSDUCER FOR OBTAINING POSITION DATA AND METHOD FOR ITS OPERATION - A measuring transducer for obtaining position data, with a transmit/receive unit having a plurality of light sources for scanning a dimensional scale, wherein the transmit/receive unit includes several light sources, in particular at least one light source having a plurality of emitters. | 10-10-2013 |
20140111189 | METHOD FOR THE CONTACTLESS DETERMINATION OF AN ELECTRICAL POTENTIAL OF AN OBJECT USING TWO DIFFERENT VALUES FOR THE ELECTRIC FLUX, AND DEVICE - A method for the contactless determination of an electrical potential of an object, involves providing an electrode which is spatially at a distance from the object, connecting the electrode to a reference potential, determining a first temporal change in an electrical state of charge of the electrode at a first value for the electric flux between the electrode and the object, determining a second temporal change in the electrical state of charge of the electrode at a second value for the electric flux between the electrode and the object, and determining the electrical potential of the object at least from the first temporal change in the electrical state of charge and the second temporal change in the electrical state of charge and from a difference between the first value and the second value for the electric flux. | 04-24-2014 |
20140145730 | DEVICE FOR THE CONTACTLESS DETERMINATION OF AN ELECTRICAL POTENTIAL OF AN OBJECT, CURRENT PROBE, AND METHOD - A device for the contactless determination of an electrical potential of an object, has an electrode and a potential controller which is electrically connected to the electrode. The potential controller changes a reference potential applied to the electrode to a final value in such a way that an electric field between the object and the electrode disappears at the final value if the electrode is located at a distance from the object. The electrical potential is determined from the final value. | 05-29-2014 |
20150082887 | SENSOR ELEMENT WITH AN ACOUSTIC EMISSION SENSOR - A sensor element includes an acoustic emission sensor for detecting acoustic emission. The sensor element has a second sensor for a second measured variable which is different from acoustic emission. Furthermore, a sensor element is provided, which includes an acoustic emission sensor for detecting acoustic emission and includes an interface for receiving an external sensor signal. | 03-26-2015 |
Patent application number | Description | Published |
20100229063 | Replacement messages for identifying and preventing errors during the transmission of realtime-critical data - A destination node in a data network for transmission of real-time data by a data telegram, the data telegram including an identification, data and a transfer status, is provided. The destination node includes a device for receiving a first data telegram, a device for storing the data of the first data telegram and an assigned timer value, a device for receiving a second data telegram and a device for replacing the stored data of the first data telegram, wherein the stored data of the first data telegram is replaced with data of the second data telegram. Further, a method and a non-transitory storage medium are provided. | 09-09-2010 |
20110022914 | Replacement messages for identifying and preventing errors during the transmission of realtime-critical data - A destination node in a data network for transmission of real-time data by a data telegram, the data telegram including an identification, data and a transfer status, is provided. The destination node includes a device for receiving a first data telegram, a device for storing the data of the first data telegram and an assigned timer value, a device for receiving a second data telegram and a device for replacing the stored data of the first data telegram, wherein the stored data of the first data telegram is replaced with data of the second data telegram. Further, a method and a non-transitory storage medium are provided. | 01-27-2011 |
Patent application number | Description | Published |
20100229063 | Replacement messages for identifying and preventing errors during the transmission of realtime-critical data - A destination node in a data network for transmission of real-time data by a data telegram, the data telegram including an identification, data and a transfer status, is provided. The destination node includes a device for receiving a first data telegram, a device for storing the data of the first data telegram and an assigned timer value, a device for receiving a second data telegram and a device for replacing the stored data of the first data telegram, wherein the stored data of the first data telegram is replaced with data of the second data telegram. Further, a method and a non-transitory storage medium are provided. | 09-09-2010 |
20110022914 | Replacement messages for identifying and preventing errors during the transmission of realtime-critical data - A destination node in a data network for transmission of real-time data by a data telegram, the data telegram including an identification, data and a transfer status, is provided. The destination node includes a device for receiving a first data telegram, a device for storing the data of the first data telegram and an assigned timer value, a device for receiving a second data telegram and a device for replacing the stored data of the first data telegram, wherein the stored data of the first data telegram is replaced with data of the second data telegram. Further, a method and a non-transitory storage medium are provided. | 01-27-2011 |