Saul
Allan Saul, Siena IT
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20150202274 | PURIFICATION OF BACTERIAL VESICLES - A two stage filtration process is used to purify immunogenic bacterial vesicles. A first step separates the vesicles from intact bacteria based on their different sizes, with the smaller vesicles passing into the filtrate (permeate). A second step then uses a finer filter to remove smaller contaminants, with the vesicles remaining in the retentate. This two stage process is extremely simple to operate but has been shown to give vesicles of high purity. | 07-23-2015 |
Allan James Saul, Castellina IT
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20140329998 | METHODS FOR MAKING SACCHARIDE-PROTEIN GLYCOCONJUGATES - The invention provides a process for the reductive amination of a carbonyl group at the reducing terminus of a polysaccharide, wherein the reductive amination is carried out at a pH between 4 and 5. The invention also provides a process for preparing a conjugate of a polysaccharide and a carrier molecule, comprising the steps of: (a) coupling the polysaccharide to a linker, to form a polysaccharide-linker compound in which the free terminus of the linker is an ester group; and (b) reacting the ester group with a primary amine group in the carrier molecule, to form a polysaccharide-linker-carrier molecule conjugate in which the linker is coupled to the carrier molecule via an amide linkage. The invention also provides a process for reducing contamination of a polysaccharide-linker compound with unreacted linker, comprising a step of precipitating unreacted linker under aqueous conditions at a pH of less than 5. | 11-06-2014 |
Allan James Saul, Castellina In Chiantl IT
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20130017219 | PURIFICATION OF BACTERIAL VESICLESAANM Di Cioccio; VitoAACI Rapolano TermeAACO ITAAGP Di Cioccio; Vito Rapolano Terme ITAANM Colucci; Anna MariaAACI Martina FrancaAACO ITAAGP Colucci; Anna Maria Martina Franca ITAANM Saul; Allan JamesAACI Castellina in ChiantlAACO ITAAGP Saul; Allan James Castellina in Chiantl IT - A two stage size filtration process is used to purify immunogenic bacterial vesicles. A first step separates the vesicles from intact bacteria based on their different sizes, with the smaller vesicles passing into the filtrate (permeate). A second step then uses a finer filter to remove smaller contaminants, with the vesicles remaining in the retentate. This two stage process is extremely simple to operate but has been shown to give vesicles of high purity. | 01-17-2013 |
Cyro Ketzer Saul, Curitiba BR
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20100116991 | METHOD FOR MEASURING BIODIESEL CONCENTRATION IN A BIODIESEL DIESEL OIL MIXTURE - This patent presents a method for measuring the concentration of biodiesel in a homogeneous biodiesel-diesel oil mixture using mid infrared radiation for use as fabrication monitor, quality control, law enforcement and multi-fueled vehicles. The method is characterized by the use of mid infrared absorption measurement in the range from 1870 to 1600 cm | 05-13-2010 |
20140246812 | PROCESS FOR PRODUCING POLYMERIC STRUCTURES THAT HAVE ACTIVATED SURFACES AND ACTIVATED POLYMERIC STRUCTURES - The present invention relates to a process for producing polymeric structures that have activated surfaces. The process proved to be simple, quick, with high production capacity and low operating costs. The process occurs by depositing a polymer solution, which is assisted by a high electric field, on a conductive liquid surface to produce particles and/or filaments that have an activated surface. More particularly, the process of the present invention has the ability to produce particles and/or filaments that have chemically activated surfaces, in a single process. | 09-04-2014 |
David Saul, Auckland NZ
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20130217026 | MICROFLUIDIC CARTRIDGE - A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge. | 08-22-2013 |
David J. Saul, Auckland NZ
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20090263809 | Methods for Identification of Bioagents - Methods for detecting and identifying known and unknown bioagents, particularly bacteria, by nucleic acid amplification and amplicon size determination are provided. Nucleic acid amplification utilises multiple primers which hybridize to conserved bioagent ribosomal sequence regions and which bracket variable bioagent ribosomal sequence regions to produce multiple amplicons that uniquely identify the bioagent. | 10-22-2009 |
20100041056 | TEMPERATURE CONTROLLED NUCLEIC-ACID DETECTION METHOD SUITABLE FOR PRACTICE IN A CLOSED-SYSTEM - The invention relates to a method that utilizes thermophilic proteases for the treatment of nucleic acids in a closed-system to be used in tandem with methods for the rapid detection of target nucleic acids present in a sample. These combined methods enable simplified, temperature-controlled devices to be used for accurate, streamline testing at the point of care for a wide variety of applications in the medical, industrial, environmental, quality control, security and research fields. | 02-18-2010 |
20100226826 | SAMPLE COLLECTION DEVICE SUITABLE FOR LOW-VOLUME EXTRACTION - A sample collection device suitable for low-volume extraction includes a substantially tubular collection vessel having a closed end, an open end, and one or more sidewalls defining a vessel chamber having a vessel volume. The device further includes a swab for sample collection. The swab formed with a substantially closed-celled polymer foam head and the swab is configured for insertion into the collection vessel. | 09-09-2010 |
David James Saul, Auckland NZ
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20090215068 | THERMOSTABLE PROTEINASES FROM THERMOPHILIC BACTERIA - The present invention relates to the preparation of a method for the preparation of nucleic acid samples, including the steps of adding at least one non-specific thermophilic enzyme to a sample containing nucleic acid for testing, and incubating said sample for a preferred period at 65-80° C. as required to effect one or more of lysis of cells, digestion of proteins, digestion of cell-wall enzymes, via activity of said thermophilic enzyme, wherein said thermophilic enzyme is substantially stable and active at 65-80° C. but which is readily autolysed and/or denatured when said sample is incubated at or above 90° C. | 08-27-2009 |
20110020819 | ISOTHERMAL DETECTION METHODS AND USES THEREOF - The present disclosure relates to methods and probes for rapid, single temperature (isothermal) detection of specific nucleic acid sequences. The methods and probes provide a simple method for detecting bioagents including bacteria and viruses, and the detection of specific genetic markers on any nucleic sequence. | 01-27-2011 |
20120070824 | THERMOSTABLE PROTEINASES FROM THERMOPHILIC BACTERIA - The present invention relates to the preparation of a method for the preparation of nucleic acid samples, including the steps of adding at least one non-specific thermophilic enzyme to a sample containing nucleic acid for testing, and incubating said sample for a preferred period at 65-80° C. as required to effect one or more of lysis of cells, digestion of proteins, digestion of cell-wall enzymes, via activity of said thermophilic enzyme, wherein said thermophilic enzyme is substantially stable and active at 65-80° C. but which is readily autolysed and/or denatured when said sample is incubated at or above 90° C. | 03-22-2012 |
Davis Jame Saul, Auckland NZ
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20100055685 | ISOTHERMAL DETECTION METHODS AND USES THEREOF - The present invention relates to methods and probes for rapid, single temperature (isothermal) detection of specific nucleic acid sequences. The methods and probes provide an easily automatable system for detecting bioagents including bacteria and viruses, and the detection of specific genetic markers on any nucleic sequence. | 03-04-2010 |
Greg Saul, London UK
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20150258440 | GENERATION OF CUSTOM MODULAR OBJECTS - A system for generating custom modular objects is described. The custom modules form part of a modular construction set from which an object can be created by a user. The object acts as a user input device for an interactive software experience. To generate a custom (i.e. non-standard) module, a virtual 3D shape is received by a module generation service. The service converts this shape into a derived 3D shape for the module, for example, ensuring that the module is shaped such that it is compatible with other modules from the modular construction set to which it will be connected for form an object and/or by adding an aperture for receiving a connector and/or electronics core. Once generated, the derived 3D shape is sent to the user in physical form or virtual form and a virtual representation of the module is provided to the interactive software experience. | 09-17-2015 |
Greg Saul, London GB
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20150258434 | GAMING SYSTEM FOR MODULAR TOYS - An interactive computer game is described which works in conjunction with a number of physical modules that a user can connect together in different ways to form a coherent physical whole object. The game receives data from the object via a wireless link, the data identifying at least which modules form part of the object and updates game play based on the data received. At some point within the game play, the game presents an objective or goal to the user which the user can only achieve by interacting with the physical object formed from the modules. In an embodiment, this interaction comprises re-arranging the modules or swapping modules to form an object with a different visual appearance, moving all or part of the object and/or interacting with a sensor on a module in the object. The game may receive further data from the object during the user interaction. | 09-17-2015 |
20150258435 | MODULAR CONSTRUCTION FOR INTERACTING WITH SOFTWARE - A modular assembly system is described which enables interaction with an interactive software experience such as a game. The system enables a coherent physical whole object to be assembled from a core module and one or more peripheral modules. The core module includes a battery, processor and a wireless module which is able to communicate with the interactive software experience which runs on a separate computing device such as a smartphone, tablet or games console. Each of the peripheral modules stores a module ID and these IDs are collected by the core module and communicated to the interactive software experience. The user experience within the interactive software experience changes dependent upon the set of modules which are connected to form the coherent physical whole object and may also be altered as a result of manipulation of the coherent physical whole object or individual modules. | 09-17-2015 |
20150258436 | DATA STORE FOR A MODULAR ASSEMBLY SYSTEM - A data store for a modular assembly system is described. The data store comprises a number of records, each record relating to a physical module in the modular assembly system and comprising a module ID, an owner ID for the module and one or more properties fields. The properties field(s) define any property of the module and different records may define different properties. At least one of the fields in each data record (e.g. the module ID or owner ID) is verified by an authentication service. A user assembles two or more modules into a coherent physical whole object to act as a user input device to an interactive software experience. The data store communicates with the interactive software experience and causes a change in behavior of the interactive software experience in response to a check of the data records for each of the modules in the object. | 09-17-2015 |
20150258458 | INTERACTIVE SMART BEADS - Interactive smart beads are described. The beads are attached to a connecting element and form a fashion item such as a necklace or bracelet. The connecting element detects the presence of beads which are part of the fashion item and also beads which are part of nearby fashion items. The connecting element also autonomously generates interactions between two or more detected beads and transmits data about the interactions to a software experience so that a user can view a graphical representation of the interactions. In various examples each bead represents a character, environment, object, etc. and the software experience displays an animated story based on the characters, environments, objects, etc. represented by the beads involved in an interaction. | 09-17-2015 |
20150258459 | STORING STATE FOR PHYSICAL MODULAR TOYS - A modular assembly system is described in which each module comprises a storage element which stores an identifier for the module and data relating to the module. At least some of the module data is variable and is updated based on user interaction with an interactive software experience (e.g. state data). Each module also comprises one or more connectors for connecting to other modules to form a coherent physical whole object. In an embodiment, the system further comprises the interactive software experience which provides user objectives which can only be satisfied by the user interacting with the object or with modules that form the object. At least one of the modules in the object comprises a communication module which passes identifiers and module data to the interactive software experience and receives updated module data from the interactive software experience for storing in one of the modules in the object. | 09-17-2015 |
Heinrich Saul, Hamburg DE
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20090211298 | Method and Apparatus for Creating an Air-Conditioned Atmosphere - The invention relates to an apparatus for creating an air-conditioned atmosphere in a transportation container ( | 08-27-2009 |
Indrek Saul, Harjumaa EE
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20120065895 | METHOD FOR MONITORING AN INDIVIDUAL'S FAT METABOLISM STATE - Method of monitoring energy consumption of an individual in an information system, comprised of periodically determining the energy balance of the individual by measuring body fat percentages (or body fat mass) at least at three consecutive moments of time and calculating change of body fat percentages (body fat mass) from two consecutive moments of time, and calculating the trends of the individual's energy balance from the changes of body fat percentages (body fat mass) and determining from the trend whether the individual is in the stage of burning or accumulating fat. The information system automatically generates recommendations for controlling energy balance based on the trends of changes of the energy balance. | 03-15-2012 |
Kirsch Saul, Waalwijk NL
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20140334269 | Shot Activated Timer System and Method - A shot activated timer system comprises a wearable housing in which control and processing components are in electrical communication with a display, input devices, a power source, a stopwatch, a motion sensor, activation signal components, optional wireless communication components, and optional audio sensors. The motion sensor detects the vibration patterns when a firearm is discharged, and pattern recognition software installed on the control and processor components identifies valid firearm shots. The system communicates with a base unit using a short-range communication protocol. The time it takes for a shooter to discharge his firearm is measured by recording the elapsed time from an activation signal until a shot is fired. When the firearm discharges, the vibration of the shot is sensed by the motion sensor and optionally additionally with the audio sensor. One or more sequential shots can be recorded, and the results can be delivered to the display. | 11-13-2014 |
Oliver Saul, Buchholz DE
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20130232691 | ANATOMICALLY SHAPED PILLOW - The present invention relates to an anatomically shaped pillow that, in particular, can be used as a whole-body pillow comprising, when viewed in plan view, at least one curved portion and at least one comparatively elongated middle portion for the body region, which middle portion makes a transition to the curved portion, wherein at least one limb of the pillow is provided for the head region, and at least one limb of the pillow is provided for the body region. It is the object of the invention to create an anatomically shaped pillow that provides a resting person in a largely stretched-out state or with the legs only slightly bent in a natural sleeping position both with support along the body, and with support in the head region. According to the invention, for this purpose the limb of the head region and the limb of the body region form an acute angle relative to each other. | 09-12-2013 |
Shai Saul, Tel Aviv IL
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20150011247 | SYSTEM AND METHOD OF TRANSMITTING DATA BETWEEN MOBILE DEVICES - It is an object of the subject matter to disclose a method performed on two or more mobile devices comprising: detecting a movement on a sending mobile device, said sending mobile device is one of the two or more mobile devices, said movement is performed on the sending mobile device; comparing the movement performed on the sending mobile device with a positioning map, wherein the positioning map comprises relative locations of the two or more mobile devices; determining a relative location of the target mobile device on the positioning map; transmitting the data from the sending mobile device to the target mobile device. | 01-08-2015 |
Stanislav Georgievich Saul, Moscow RU
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20130261902 | Automatic Control of a Joystick for Dozer Blade Control - Dozers outfitted with manual or electric valves can be retrofitted with a control system for automatically controlling the elevation and orientation of the blade. No modification of the existing hydraulic drive system or existing hydraulic control system is needed. An arm is operably coupled to the existing joystick, whose translation controls the elevation and orientation of the blade. The arm is driven by an electrical motor assembly. Measurement units mounted on the dozer body or blade provide measurements corresponding to the elevation or orientation of the blade. A computational system receives the measurements, compares them to target reference values, and generates control signals. Drivers convert the control signals to electrical drive signals. In response to the electrical drive signals, the electrical motor assembly translates the arm, which, in turn, translates the joystick. If necessary, an operator can override the automatic control system by manually operating the joystick. | 10-03-2013 |