Santalucia
John Santalucia, Grosse Pointe Woods, MI US
Patent application number | Description | Published |
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20110112816 | SYSTEM AND METHODS FOR THREE DIMENSIONAL MOLECULAR STRUCTURAL ANALYSIS - The present invention relates to methods and systems for the accurate prediction of nucleic acid, e.g., RNA and DNA, and other macromolecular and biomolecular three-dimensional structure from sequence and constraint information. | 05-12-2011 |
20110112817 | SYSTEM AND METHODS FOR THREE DIMENSIONAL MOLECULAR STRUCTURAL ANALYSIS - The present invention relates to methods and systems for the accurate prediction of nucleic acid, e.g., RNA and DNA, and other macromolecular and biomolecular three-dimensional structure from sequence and constraint information. | 05-12-2011 |
20160125132 | DETERMINING NUCLEIC ACID CONCENTRATION BY COUNTING NUCLEIC ACID COPIES - Provided herein is technology relating to quantifying the concentration of nucleic acids and particularly, but not exclusively, to methods for modeling data from a single quantitative amplification reaction, e.g., a PCR assay, to determine the initial concentration of a DNA target. In alternative embodiments, additional unknowns may be used, e.g., parameters for Bn, which is the concentration of probe at cycle n (and which changes in TAQMAN assays due to cleavage of the probe), EC for efficiency of probe cleavage, PDC for apparent probe dissociation constant, etc. | 05-05-2016 |
John Santalucia, Grosse Point Woods, MI US
Patent application number | Description | Published |
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20130018635 | SYSTEM AND METHODS FOR THREE DIMENSIONAL MOLECULAR STRUCTURAL ANALYSIS - The present invention relates to methods and systems for the accurate prediction of nucleic acid, e.g., RNA and DNA, and other macromolecular and biomolecular three-dimensional structure from sequence and constraint information. | 01-17-2013 |
John Santalucia US
Patent application number | Description | Published |
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20160125132 | DETERMINING NUCLEIC ACID CONCENTRATION BY COUNTING NUCLEIC ACID COPIES - Provided herein is technology relating to quantifying the concentration of nucleic acids and particularly, but not exclusively, to methods for modeling data from a single quantitative amplification reaction, e.g., a PCR assay, to determine the initial concentration of a DNA target. In alternative embodiments, additional unknowns may be used, e.g., parameters for Bn, which is the concentration of probe at cycle n (and which changes in TAQMAN assays due to cleavage of the probe), EC for efficiency of probe cleavage, PDC for apparent probe dissociation constant, etc. | 05-05-2016 |