Saltzman, US
Brian J. Saltzman, Seattle, WA US
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20100070501 | ENHANCING AND STORING DATA FOR RECALL AND USE USING USER FEEDBACK - A user of a computing device may see an item of interest she would like to remember for future reference. The user captures data of the item of interest and submits it to a memory enhancement service for enhancement and storage. The service submits the captured data to a human interaction task system which distributes the captured data to one or more human workers which to identify the item of interest, determine the user's interest in the item, and provide information regarding the item based on this determined interest. To facilitate the enhancement process, the user may add indications to the captured data prior to submission. Alternatively or additionally, the service may electronically submit queries to the user. The enhanced data returned from the human interaction task system is then stored by the memory enhancement service for subsequent recall by the user and possible use by the user. | 03-18-2010 |
Charles Saltzman, Salt Lake City, UT US
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20090105710 | Mechanical Distractor To Facilitate Surgery And Evaluation Of Joints - A medical apparatus having a tensioning device secured to a fixed point; a wire or pin inserted transversely through a bone; and a tension line connecting the tensioning device to the wire or pin. The tension line transmits a force from the tensioning device to the wire or pin to facilitate distraction of a joint of a subject. | 04-23-2009 |
Charles L. Saltzman, Salt Lake City, UT US
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20100179591 | PATCH AUGMENTATION OF ACHILLES TENDON REPAIRS - A method according to embodiments of the present invention for repairing an Achilles tendon that has completely or partially ruptured leaving a distal stump extending from a calcaneus and a proximal stump, the proximal stump having a proximal stump end, and the distal stump having a distal stump end, includes attaching a first suture to the distal stump, positioning an augmentation patch against an anterior portion of the Achilles tendon, attaching a second suture to the proximal stump and to the augmentation patch, apposing the proximal stump end and the distal stump end such that a gap between the proximal stump end and distal stump end is minimized or eliminated, joining the first suture with the second suture to secure the proximal stump to the distal stump, and attaching the augmentation patch to the calcaneus. | 07-15-2010 |
20100305572 | ANKLE PROSTHESIS METHODS - Methods of implanting an ankle prosthesis in a subject having an ankle joint in need of replacement. | 12-02-2010 |
20110087229 | BONE FIXATION AND COMPRESSION SYSTEMS - Systems and methods for stabilizing and/or compressing portions of bone are provided. In some aspects, a bone plate system may comprise a plate having a bone engaging surface. The plate may be fastened to two bone portions having a joint line therebetween. The system may also include a keel projecting from the bone engaging surface. The keel may extend into the bone portions and span the joint line when the plate is fastened to the bone portions. In some aspects, a ratio of an average thickness of the plate to an average width of the plate may be less than or equal to about 0.11. | 04-14-2011 |
20110087295 | BONE FIXATION SYSTEMS - Systems and methods for stabilizing and/or compressing portions of bone are provided. In some aspects, a bone plate system may comprise a plate having a bone engaging surface. The plate may be fastened to two bone portions having a joint line therebetween. The system may also include a keel projecting from the bone engaging surface. The keel may extend into the bone portions and span the joint line when the plate is fastened to the bone portions. In some aspects, a ratio of an average thickness of the plate to an average width of the plate may be less than or equal to about 0.11. | 04-14-2011 |
20110253151 | POSITIONING DEVICE FOR ANKLE JOINT REPLACEMENT SURGERY - A positioning device for ankle joint replacement surgery. | 10-20-2011 |
20110306976 | BONE PLATE AND KEEL SYSTEMS - Systems and methods for stabilizing portions of bone are provided. In some aspects, a bone plate system includes a plate configured to be fastened to at least one bone portion. The plate includes a keel slot and a locking assembly. The bone plate system also includes a keel configured to extend into the at least one bone portion through the keel slot. The locking assembly is configured to substantially prevent the keel from dislodging from the plate when the keel extends into the at least one bone portion through the keel slot. | 12-15-2011 |
20130267955 | SYSTEMS FOR CONTROLLING BONE GROWTH - Systems and methods for stabilizing portions of bone are provided. In some aspects, a bone fixation system can include a plate configured to be fastened to a growing bone to control growth of the bone in at least one direction. The system can include a keel structure having a longitudinal axis. The keel can extend from the plate into the bone to permit bone growth along the keel longitudinal axis on one side of the bone while the plate generally inhibits growth on the other side of the bone. | 10-10-2013 |
20140236157 | POSITIONING DEVICE FOR ANKLE JOINT REPLACEMENT SURGERY - A positioning device for ankle joint replacement surgery. | 08-21-2014 |
Dan Saltzman, Chicago, IL US
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20130180048 | Exercise Yoga Mat and Method of Using Same - An Exercise Yoga mat and method of use whereby the mat has printed indicia for measuring distance along the surface of the mat while executing yoga exercise positions. | 07-18-2013 |
Daniel Saltzman, Chicago, IL US
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20160136476 | EXERCISE MAT - An exercise mat including a material sized and shaped to support at least one user body part thereon, the material having an upper planar surface, a single starting point representing a number zero on the upper planar surface, and at least two series of sequential integers disposed on the upper planar surface and extending from the single starting point. Each of the at least two series of sequential integers corresponding to a coordinate and placement site for a body part of a user to facilitate measurement of a linear distance along the upper planar surface | 05-19-2016 |
Daniel Saltzman, Mendota Heights, MN US
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20080260645 | METHOD AND USE OF COLD-PRESSED BOTANIC SEED OILS FOR LOWERING BLOOD PRESSURE AND LDL CHOLESTEROL - A method of lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: (a) administering to the human subject a mixture of cold-pressed botanic seed oils; (b) administering to the human subject the mixture of cold-pressed botanic seed oils and a mixture of botanic seed flours; and (c) lowering the human subject's diastolic blood pressure and LDL cholesterol. | 10-23-2008 |
Daniel A. Saltzman, Mendota Heights, MN US
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20090324759 | IMMUNE ENHANCEMENT BY SEED OIL AND/OR SEED FLOUR - A method of treating a subject requiring immune mediation includes administering to the subject an immunostimulatory composition which contains black raspberry seed oil. Administering this composition stimulates the production of certain immune cells, including NK cells and CD8(+) lymphocytes. Administering the composition by this method also provides a method of treating, preventing, or ameliorating a condition or disease in the subject requiring enhanced immune system support. | 12-31-2009 |
20100098665 | METHOD OF CANCER TREATMENT - A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated | 04-22-2010 |
20130045525 | METHOD OF CANCER TREATMENT - A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated | 02-21-2013 |
Darin Saltzman, Glendale, CA US
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20140018293 | MINIMIZING INTESTINAL DYSFUNCTION - Techniques are discloded for treating or reducing sumptoms associated with abdominal dysfunction or ileus following surgery or other abdominal episode by treating the area with a combination of one or more protease, antibacterial compound, and inflammatory lipid mediator. | 01-16-2014 |
David J. Saltzman, Minneapolis, MN US
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20110029027 | MEDICAL DEVICE SURFACE ELECTRODE - Structures and methods relating to electrodes for incorporation into a feedthrough with a profile adapted for subcutaneous sensing of physiologic and cardiac signals. Electrode assemblies are adapted for integration with feedthroughs and provide reliable insulation from the implantable medical device housing. Various structures and manufacturing processes are implemented to provide a large sensing surface with a low profile. The subcutaneous sensing electrode assembly can provide a leadless sensing system and further enhances installation and follow-up procedures. | 02-03-2011 |
Elliot Saltzman, Boston, MA US
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20120238914 | ACTIVELY CONTROLLED ORTHOTIC DEVICES - An actively controlled orthotic device includes active components that dynamically change the structural characteristics of the orthotic device according to the orientation and locomotion of the corresponding body part, or according to the changing needs of the subject over a period of use. Accordingly, the orthotic device can be effectively employed to provide locomotion assistance, gait rehabilitation, and gait training. Similarly, the orthotic device may be applied to the wrist, elbow, torso, or any other body part. The active components may be actuated to effectively transmit force to a body part, such as a limb, to assist with movement when desired. Additionally or alternatively, the active components may also be actuated to provide support of varying rigidity for the corresponding body part. | 09-20-2012 |
Eric Saltzman, Menlo Park, CA US
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20100017239 | Forecasting Discovery Costs Using Historic Data - A computer-implemented method and apparatus for forecasting discovery costs includes probability-based forecasting and capturing historic stage transition data for each matter stage regarding the duration of each historic matter stage and regarding the number of new custodians and data sources added during that matter stage. The stage transition data is statistically and aggregated by stage and matter type. Progress for existing matters is extrapolated. Initiation of future matters is forecast by extrapolating how many new matters are expected to be initiated over the duration of a forecasting period. The average pace of progress is extrapolated from the historic data. Volumes of production and custodians are forecasted by extrapolation using quantitative characteristics of the historic stage transition data. | 01-21-2010 |
Greg D. Saltzman, Perkasie, PA US
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20100289669 | REAL TIME TEMPERATURE AND LOCATION TRACKER - A shipper having an outer housing with a temperature sensitive payload and a temperature/location tracker disposed therein. The outer housing has a body having an interior surface bounding a compartment that is accessed through an opening. A first panel is coupled with the body and configured to extend over at least a portion of the opening, with a first access port extending through the first panel. The payload and temperature/location tracker are disposed within the compartment of the body. The temperature/location tracker includes a first temperature probe, a GPS receiver, a cellular modem, and a GPS antenna. The GPS antenna is disposed so as to be aligned with the first access port when the shipper is in a fully assembled state such that the GPS antenna is directly accessible through the first access port. The temperature/location tracker monitors and periodically transmits temperature and location values of the shipper over a cellular communication network. | 11-18-2010 |
Jay A. Saltzman, Hinsdale, IL US
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20090057354 | FLEXIBLE CARRIER - A flexible carrier for carrying a plurality of containers includes a flexible sheet and a plurality of container receiving apertures formed in the flexible sheet wherein the plurality of container receiving apertures are formed in a staggered array wherein each row within the array includes a different number, offset and/or geometry of container receiving apertures from each adjacent row. | 03-05-2009 |
20110266167 | FLEXIBLE CARRIER - A flexible carrier for carrying a plurality of containers includes a flexible sheet and a plurality of container receiving apertures formed in the flexible sheet wherein the plurality of container receiving apertures are formed in a staggered array wherein each row within the array includes a different number, offset and/or geometry of container receiving apertures from each adjacent row. | 11-03-2011 |
Jeff Saltzman, San Francisco, CA US
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20150288951 | AUTOMATED CAMERA CALIBRATION METHODS AND SYSTEMS - Methods and systems are disclosed for calibrating a camera using a calibration target apparatus that contains at least one fiducial marking on a planar surface. The set of all planar markings on the apparatus are distinguishable. Parameters of the camera are inferred from at least one image of the calibration target apparatus. In some embodiments, pixel coordinates of identified fiducial markings in an image are used with geometric knowledge of the apparatus to calculate camera parameters. | 10-08-2015 |
20150288956 | CALIBRATION TARGET FOR VIDEO PROCESSING - An apparatus is disclosed which may serve as a target for calibrating a camera. The apparatus comprises one or more planar surfaces. The apparatus includes at least one fiducial marking on a planar surface. The set of all planar markings on the apparatus are distinguishable. | 10-08-2015 |
Jeffrey Saltzman, San Francisco, CA US
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20140002452 | ADJUSTING STEREO IMAGES | 01-02-2014 |
Jeremy Saltzman, Sunnyvale, CA US
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20130257626 | BUILDING MANAGEMENT SYSTEM WITH PRIVACY-GUARDED ASSISTANCE MECHANISM AND METHOD OF OPERATION THEREOF - A method for operating a building management system includes: identifying a movement-pattern from a sensed attribute at a first sensor; determining a behavior-pattern at the first sensor when the movement-pattern matches a template-pattern; transmitting the behavior-pattern and the sensed attribute from the first sensor to a second sensor; and tracking the sensed attribute at the second sensor for displaying on a device. | 10-03-2013 |
20130262654 | RESOURCE MANAGEMENT SYSTEM WITH RESOURCE OPTIMIZATION MECHANISM AND METHOD OF OPERATION THEREOF - A method for operating a resource management system includes: identifying a total-usage status of a resource currently being supplied; calculating a current production amount of supplying the resource using the total-usage status; calculating an assessment structure directly reflecting the current production amount; adjusting the assessment structure for modifying behavior associated with the current consumption of the resource. | 10-03-2013 |
Mark W. Saltzman, New Haven, CT US
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20100098767 | CONVECTION ENHANCED DELIVERY APPARATUS, METHOD, AND APPLICATION - An embodiment of the invention is directed to a microfabrπcated, silicon-based, Convection Enhanced Delivery (CED) device The device comprises a silicon shank portion, at least one individual parylene channel disposed along at least a part of an entire length of the shank, wherein the channel has one or more dimensioned fluid exit ports disposed at one or more respective locations of the channel and a fluid (drug) input opening The fluid input opening may be configured or adapted to be connected to a fluid reservoir and/or a pump and/or a meter and/or a valve or other suitable control device(s) or apparatus that supplies and/or delivers fluid (e g, a drug) to the microfabricated device The device may have multiple channels disposed side by side or in different surfaces of the device | 04-22-2010 |
20110008451 | COMPOSITIONS AND METHODS FOR CONTROLLED DELIVERY OF INHIBITORY RIBONUCLEIC ACIDS - Polymeric nanoparticles encapsulating inhibitory ribonucleic acids (RNAs) and methods of their manufacture and use are provided. Advantageous properties of the nanoparticles include: 1) high encapsulation efficiency of inhibitory RNAs into the nanoparticles, 2) small size of the nanoparticles that increases cell internalization, and 3) sustained release of encapsulated inhibitory RNAs by the nanoparticles that allows for administration of an effective amount of inhibitory RNAs to cells or tissues over extended periods of time. Encapsulation efficiency of inhibitory RNAs into the nanoparticles is greatly increased by complexing the inhibitory RNAs to polycations prior to encapsulation. Methods of using the polymeric nanoparticles for treating or inhibiting diseases or disorders are provided. | 01-13-2011 |
Martin Saltzman, Nelsonville, NY US
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20150344677 | Effect Pigments - A high chroma effect pigment includes a platelet substrate and an optical coating formed on the platelet substrate. The optical coating includes a first high refractive index layer, a second high refractive index layer on the first high refractive index layer, and a diffused third material having a range of diffusion between 100% to partial diffusion in the first high refractive index layer, the second high refractive index layer, or both the first and the second high refractive index layers. The first and second high refractive index layers independently have a refractive index of about >1.65. The diffused third material is SiO | 12-03-2015 |
Stephen J. Saltzman, Annapolis, MD US
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20130035949 | Integrated wellness index and method of measuring overall wellness and treatment - A tool and method of diagnosis and treatment of a patient by employing an integrated wellness index to achieve maximum health and to determine the underlying causes of disease states. A wellness index assigns a point system for essential health factors to measure various health parameters and overall health of a patient and assist the tracking of a patient's health status over time. | 02-07-2013 |
William Mark Saltzman, New Haven, CT US
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20090239789 | METHODS OF TREATMENT WITH DRUG LOADED POLYMERIC MATERIALS - Polymeric microparticles have been developed which encapsulate therapeutic compounds such as drugs, cellular materials or components, and antigens, and can have targeting ligands directly bound to the microparticle surface. Preferred applications include use in tissue engineering matrices, wound dressings, bone repair or regeneration materials, and other applications where the microparticles are retained at the site of application or implantation. Another preferred application is in the use of microparticles to deliver anti-proliferative agents to the lining of blood vessels following angioplasty, transplantation or bypass surgery to prevent or decrease restenosis, and in cancer therapy. In still another application, the microparticles are used to treat or prevent macular degeneration when administered to the eye, where agents such as complement inhibitors are administered. | 09-24-2009 |
20090269397 | TARGETED AND HIGH DENSITY DRUG LOADED POLYMERIC MATERIALS - Polymeric delivery devices have been developed which combine high loading/high density of molecules to be delivered with the option of targeting. As used herein, “high density” refers to microparticles having a high density of ligands or coupling agents, which is in the range of 1000-10,000,000, more preferably between 10,000 and 1,000,000 ligands per square micron of microparticle surface area. A general method for incorporating molecules into the surface of biocompatible polymers using materials with an HLB of less than 10, more preferably less than 5, such as fatty acids, has been developed. Because of its ease, generality and flexibility, this method has widespread utility in modifying the surface of polymeric materials for applications in drug delivery and tissue engineering, as well other fields. Targeted polymeric microparticles have also been developed which encapsulate therapeutic compounds such as drugs, cellular materials or components, and antigens, and have targeting ligands directly bound to the microparticle surface. Preferred applications include use in tissue engineering matrices, wound dressings, bone repair or regeneration materials, and other applications where the microparticles are retained at the site of application or implantation. Another preferred application is in the use of microparticles to deliver anti-proliferative agents to the lining of blood vessels following angioplasty, transplantation or bypass surgery to prevent or decrease restenosis, and in cancer therapy. In still another application, the microparticles are used to treat or prevent macular degeneration when administered to the eye, where agents such as complement inhibitors are administered. | 10-29-2009 |
20100104503 | MODULAR NANOPARTICLES FOR ADAPTABLE VACCINES - Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric particle and adaptor elements which modularly couple functional elements to the particle. The modular design of these vaccine compositions, which involves flexible addition and subtraction of antigen, adjuvant, immune potentiators, molecular recognition and transport mediation elements, as well as intracellular uptake mediators, allows for exquisite control over variables that are important in optimizing an effective vaccine delivery system. | 04-29-2010 |
20100151436 | Methods for Ex Vivo Administration of Drugs to Grafts Using Polymeric Nanoparticles - Methods for ex vivo administration of drugs to grafts using polymeric micro- and nanoparticles and applications for these methods are described herein. The particles contain encapsulated molecules which are released locally at the site of implantation and function to prevent graft rejection or aid in the proper adaptation of the graft to the host. The disclosed methods may be used to inhibit or reduce hyperplasia and stenosis of vascular grafts or to prevent graft rejection. | 06-17-2010 |
20110268810 | POLYMERIC MATERIALS LOADED WITH MUTAGENIC AND RECOMBINAGENIC NUCLEIC ACIDS - Polymeric microparticles are used to deliver recombinagenic or mutagenic nucleic acid molecules such as donor nucleic acid alone, or in combination with triplex-forming molecules, to induce a site-specific mutation in the target DNA. Target cells endocytose the particles, releasing the nucleic acid molecules inside of the cell, where they induce mutagenesis or recombination at a target site. The examples demonstrate that triplex forming oligonucleotides, preferably PNAs, preferably in combination with a donor nucleotide molecule, can be encapsulated into polymeric microparticles, which are delivered into cells. Results demonstrate significantly greatly levels of uptake and expression, and less cytotoxicity, as compared to direct transfer of the nucleic acid molecules into the cell by nucleofection. | 11-03-2011 |
20150118311 | Highly Penetrative Nanocarriers for Treatment of CNS Disease - Brain-penetrating polymeric nanoparticles that can be loaded with drugs and are optimized for intracranial convection-enhanced delivery (CED) have been developed. In the preferred embodiment, these are loaded with FDA-approved compounds, identified through library screening to target brain cancer stem cells (BSCSs). The particles are formed by emulsifying a polymer-drug solution, then removing solvent and centrifuging at a first force to remove the larger particles, then collecting the smaller particles using a second higher force to sediment the smaller particles having a diameter of less than 100 nm, more preferably less than 90 nanometers average diameter, able to penetrate brain interstitial spaces. | 04-30-2015 |
20150125384 | MODULAR NANODEVICES FOR SMART ADAPTABLE VACCINES - Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric particle and adaptor elements which modularly couple functional elements to the particle. The modular design of these vaccine compositions, which involves flexible addition and subtraction of antigen, adjuvant, immune potentiators, molecular recognition and transport mediation elements, as well as intracellular uptake mediators, allows for exquisite control over variables that are important in optimizing an effective vaccine delivery system. | 05-07-2015 |
W. Mark Saltzman, New Haven, CT US
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20140342003 | ENZYMATIC SYNTHESIS OF POLY(AMINE-CO-ESTERS) AND METHODS OF USE THEREOF FOR GENE DELIVERY - Poly(amine-co-ester) polymers, methods of forming active agent-load nanoparticles therefrom, and methods of using the nanoparticles for drug delivery are disclosed. The nanoparticles can be coated with an agent that reduces surface charge, an agent that increases cell-specific targeting, or a combination thereof. Typically, the loaded nanoparticles are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the nanoparticles are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition. | 11-20-2014 |
20140371712 | CONVECTION ENHANCED DELIVERY APPARATUS, METHOD, AND APPLICATION - An embodiment of the invention is directed to a microfabricated, silicon-based, Convection Enhanced Delivery (CED) device. The device comprises a silicon shank portion, at least one individual parylene channel disposed along at least a part of an entire length of the shank, wherein the channel has one or more dimensioned fluid exit ports disposed at one or more respective locations of the channel and a fluid (drug) input opening. The fluid input opening may be configured or adapted to be connected to a fluid reservoir and/or a pump and/or a meter and/or a valve or other suitable control device(s) or apparatus that supplies and/or delivers fluid (e.g., a drug) to the microfabricated device. The device may have multiple channels disposed side by side or in different surfaces of the device. The device may be rigid, or flexible, in which case a flexible device can be attached to a bio-degradable support scaffold that provides sufficient structural rigidity for insertion of the device into the target tissue. In certain “functionalized” embodiments of the invention, the CED device is equipped with integrated electrodes and/or a sensor (e.g., glutamate) to detect and convey selective parametric information. Another embodiment of the invention is directed to a CED method for drugs and/or other agents. The method may comprise the delivery of enzymes or other materials to modify tissue permeability and improve drug diffusion. Another embodiment of the invention is directed to a method for making a device for CED of drugs. | 12-18-2014 |
20150073041 | FORMULATIONS FOR TARGETED RELEASE OF AGENTS TO LOW PH TISSUE ENVIRONMENTS OR CELLULAR COMPARTMENTS AND METHODS OF USE THEREOF - Polyamine-co-ester-co-ortho ester) polymers, methods of forming active agent-load nanoparticles therefrom, and methods of using the nanoparticles for drug delivery are disclosed. The nanoparticles can be coated with an agent that reduces surface charge, an agent that increases cell-specific targeting, or a combination thereof. Typically, the loaded nanoparticles are less toxic, more efficient at drug delivery, or a combination thereof compared to a control or other transfection reagents. | 03-12-2015 |
Xylon Saltzman, Seattle, WA US
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20150379884 | AIRCRAFT SIMULATOR - A modular aircraft simulator is constructed from an aluminum exoskeleton structure supporting a panel skin formed of flexible, resilient panels releasably affixed to an interior of the exoskeleton. The exoskeleton and panel skin together create an enclosure that is representative of an aircraft cockpit. The aircraft simulator includes a system of integrated hardware and software that permit an instructor (e.g., operator of the instructor console) to provide instruction to the student (e.g., operator of the aircraft simulator) from a remote location via data transfer over a network such as the internet. A remote interface system includes a multi-step identity verification process to allow the instructor to verify and confirm the identity of the student prior to commencing a training session and throughout the training session. | 12-31-2015 |