Saha, US
Abhisek Saha, Williamantic, CT US
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20140278967 | DETERMINING TARGET CUSTOMERS DURING MARKETING - A method of determining which customers to target during marketing is disclosed. Parameters are estimated from inputs of sample customers from statistical procedures, and an approximation model is created for each of the estimated parameters. The approximation models are applied to transaction data collect for customers on a customer list. For each customer, the transaction data is applied to the approximation models to determine a dropout probability and a transaction rate. A likelihood of repeat purchase is determined for each customer based on the dropout probability and the transaction rate. | 09-18-2014 |
Amit K. Saha, Plano, TX US
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20140063312 | METHODS FOR COMBINING CAMERA AND PROJECTOR FUNCTIONS IN A SINGLE DEVICE - Described are handheld devices with combined image capture and image projection functions. One embodiment includes modulating and capturing a light beam along the same optic path. In another embodiment, the optical components are operable to switch between projection and capture modes. In yet another embodiment, the optical components may be formed on the same semiconductor substrate thereby increasing functionality. | 03-06-2014 |
Amit Kumar Saha, Houston, TX US
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20130336297 | INCORPORATION OF MESH BASE STATIONS IN A WIRELESS SYSTEM - Incorporating and operating a mesh base station in a wireless network is described. The mesh base station can utilize common wireless resource allocations as a corresponding wireless base station while transmitting to wireless subscriber stations during the same time period. The mesh base station obtains a data packet from the wireless base station over a backhaul link during a scheduled time period and transmits the data packet to the designated wireless subscriber station during another scheduled time period. The wireless base station and the mesh base station can also receive data packets from wireless subscriber stations during a same time period. A wireless network can be configured with two mesh base stations at an approximate boundary of two adjacent sector coverage areas, where a coverage area is supported by a wireless base station and each mesh base station supports wireless subscriber stations within a coverage radius. | 12-19-2013 |
Aniket Mukul Saha, Austin, TX US
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20080284469 | REDUCED POWER CONSUMPTION LIMITED-SWITCH DYNAMIC LOGIC (LSDL) CIRCUIT - An limited-switch dynamic logic (LSDL) circuit provides reduced power consumption by reducing clock power dissipation. By clocking LSDL gates with a clock signal having a reduced voltage swing in the evaluation phase, the LSDL gates are permitted to operate, while reducing the clock power consumption dramatically. Since clock power consumption dominates in LSDL circuits, the reduction in clock power dissipation results in a significant reduction in overall circuit power consumption. The reduced swing clock is produced at a plurality of local clock buffers by supplying the local clock buffers with an extra power supply rail that is switched onto the clock distribution lines by the local clock buffers in response to the full-swing evaluate phase clock received from the global clock distribution network by the local clock buffers. | 11-20-2008 |
Anjan Saha, Hamden, CT US
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20090124808 | PROCESS FOR PREPARING ACYCLIC HCV PROTEASE INHIBITORS - Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: | 05-14-2009 |
20090124809 | PROCESS FOR PREPARING ACYCLIC HCV PROTEASE INHIBITORS - Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: | 05-14-2009 |
20130211089 | INDENOPYRIDINE DERIVATIVES - Disclosed is a compound of formula (I) | 08-15-2013 |
20130244996 | BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION - The present invention relates to compounds of formula (I): | 09-19-2013 |
Anjan Saha, New Milford, CT US
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20140107343 | INDENOPYRIDINE DERIVATIVES - Disclosed is a compound of formula (I) | 04-17-2014 |
Anupam Saha, Austin, TX US
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20140249957 | MOBILE APPLICATION FOR IN-STORE USE - According to some embodiments of this disclosure, a software application running on a mobile device (e.g., a tablet or smartphone device) is provided which may be used by a sales associate in a physical store of an entity to assist a consumer in shopping for products or services. For example, the software application may be used by the associate to retrieve and display user generated content (UGC) items related to the products or services to assist the consumer in shopping. The software application may also store a browsing history for the user, and the sales associate may then transmit the browsing history to the consumer (e.g., via email or other electronic message). | 09-04-2014 |
Arup Saha, Portland, OR US
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20120125492 | Ultratough high-strength weldable plate steel - A transformation toughened, high-strength steel alloy useful in plate steel applications achieves extreme fracture toughness (Cv & gt; 80 ft-lbs corresponding to KId=200 ksi.in ½) at strength levels of 150-180 ksi yield strength, is weldable and formable. The alloy is characterized by dispersed austenite stabilization for transformation toughening to a weldable, bainitic plate steel and is strengthened by precipitation of M2C carbides in combination with copper and nickel. The desired microstructure is a matrix containing a bainite-martensite mix, BCC copper and M2C carbide particles for strengthening with a fine dispersion of optimum stability austenite for transformation toughening. The bainite-martensite mix is formed by air-cooling from solution treatment temperature and subsequent aging at secondary hardening temperatures to precipitate the toughening and strengthening dispersions. | 05-24-2012 |
Ashis Saha, Stow, MA US
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20100317649 | S1P Receptor Modulating Compounds and Use Thereof - The present invention relates to compounds that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. In certain embodiments, the compounds of the invention relate to aryl oxoimidazolidinyls. | 12-16-2010 |
20110212940 | S1P Receptor Modulating Compounds and Use Thereof - The present invention relates to compounds of the general formula (I) that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds may be used as immunomodulators, e.g., for treating or preventing diseases such as autoimmune and related immune disorders including systemic lupus erythematosus, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis, myasthenia gravis, rheumatoid arthritis, non-glomerular nephrosis, hepatitis, Behçet's disease, glomerulonephritis, chronic thrombocytopenic purpura, hemolytic anemia, hepatitis and Wegner's granuloma; and for treating other conditions. | 09-01-2011 |
20120115850 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT - The invention relates to 5-HT | 05-10-2012 |
Ashis K. Saha, Harleysville, PA US
Patent application number | Description | Published |
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20090281336 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES - The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus. | 11-12-2009 |
Ashis K. Saha, Stow, MA US
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20100210633 | CARBOXAMIDE COMPOUNDS AND THEIR USE - Chemokine receptor antagonists, in particular, compounds of Formula (I) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein. | 08-19-2010 |
20110059945 | S1P Receptor Modulating Compounds and Use Thereof - The present invention relates to compounds of the general formula (I) that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds may be used as immunomodulators, e.g., for treating or preventing diseases such as autoimmune and related immune disorders including systemic lupus erythematosus, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis, myasthenia gravis, rheumatoid arthritis, non-glomerular nephrosis, hepatitis, Behçet's disease, glomerulonephritis, chronic thrombocytopenic purpura, hemolytic anemia, hepatitis and Wegner's granuloma; and for treating other conditions. | 03-10-2011 |
20110237529 | Adenosine Analogs and Their Use - The invention provides adenosine analog compounds that act at P2Y receptors, e.g., the P2Y | 09-29-2011 |
20120214809 | Aminoindane Compounds and Use Thereof in Treating Pain - The present application provides novel aminoindane compounds and methods for preparing and using these compounds. These compounds are useful in treating pain and/or itch in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) or (II) and a TRPV 1 receptor activator. In one embodiment, the TRPV 1 receptor activator is lidocaine. | 08-23-2012 |
20130101667 | Cyclohexylamines - The present application provides novel compounds and methods for preparing and using these compounds. These compounds are useful in treating pain, itch, overactive bladder and/or interstitial cystitis in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine. | 04-25-2013 |
20140038912 | ADENOSINE ANALOGS AND THEIR USE - Provided are adenosine analog compounds of the general formula that act as P2Y receptors, e.g., the P2Y | 02-06-2014 |
20140213552 | CYCLOHEXYLAMINES - The present application provides novel compounds and methods for preparing and using these compounds. These compounds are useful in treating pain, itch, overactive bladder and/or interstitial cystitis in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine. | 07-31-2014 |
Ashis Kumar Saha, Stow, MA US
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20100168080 | NOVEL COMPOUNDS USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS - The present invention relates to novel morpholine, oxazapane and piperidine derivatives that act as ligands for CC chemokine receptors, such as CCR1. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds. | 07-01-2010 |
Avijit Saha, Somers, NY US
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20080294635 | System for Conducting Searches on the World Wide Web Enabling the Search Requester to Modifying the Domain Context of a Search Responsive to an Excessive Number of Hits on Combinations of Keywords - The user requesting the search is enabled to analyze the list of excessive hits in a manner organized through a Web content manager on the user's display screen, and reduce the excessive hits through the elimination of extraneous domains or subdomains captured by the search. | 11-27-2008 |
Avishek Saha, Houston, TX US
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20130095314 | IMMOBILIZED CARBON NANOTUBES ON VARIOUS SURFACES - In some embodiments, the present invention provides methods of immobilizing carbon nanotubes on a surface, wherein the method comprises: (1) mixing carbon nanotubes with a superacid to form a carbon nanotube solution; and (2) exposing the carbon nanotube solution to the surface. The exposing results in the immobilization of the carbon nanotubes on the surface. In some embodiments, the method occurs without the utilization of carbon nanotube wrapping molecules. Other embodiments of the present invention pertain to systems that comprise immobilized carbon nanotubes on a surface, as developed by the aforementioned methods. | 04-18-2013 |
20140255291 | LIQUID CRYSTALS FROM SINGLE-WALLED CARBON NANOTUBE POLYELECTROLYTES AND THEIR USE FOR MAKING VARIOUS MATERIALS - In some embodiments, the present disclosure pertains to methods of forming a solution of single-walled carbon nanotube polyelectrolytes in a liquid crystalline phase. In some embodiments, such methods comprise: (a) providing single-walled carbon nanotube polyelectrolytes; and (b) mixing the single-walled polyelectrolytes with a polar aprotic solvent to form a mixture, where the mixing results in the formation of single-walled carbon nanotubes in the liquid crystalline phase. In some embodiments, the polar aprotic solvent comprises crown ether. In some embodiments, the present disclosure pertains to a method of making single-walled carbon nanotube fibers. Further embodiments of the present disclosure pertain to a method of making a single walled carbon nanotube composite. In some embodiments, the present disclosure pertains to an article comprising neat aligned carbon nanotubes. | 09-11-2014 |
Badal Saha, Peoria, IL US
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20110212458 | Methods for Production of Xylitol in Microorganisms - The invention provides biosynthetic routes to xylitol production that do not require pure | 09-01-2011 |
Badal C. Saha, Peoria, IL US
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20090023195 | Bio-based method for making mannitol - Mannitol is produced in a highly efficient fermentative method using | 01-22-2009 |
Barna Saha, Hyattsville, MD US
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20120130935 | Conservation dependencies - Given a set of data for which a conservation law is an appropriate characterization, “hold” and/or “fail” tableaux are provided for the underlying conservation law, thereby providing a conservation dependency whereby portions of the data for which the law approximately holds or fails can be discovered and summarized in a semantically meaningful way. | 05-24-2012 |
Basudeb Saha, Missouri City, TX US
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20130060000 | METHODS FOR PRODUCING CROSSLINKABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMERS - Embodiments of the invention provide for a method of producing a silylated polyoxyalkylene polymer having at least one crosslinkable silyl group and at least one hydroxyl group in each molecule. The method comprises providing a polyoxyalkylene polymer having at least one unsaturated group and at least one alcoholic hydroxyl group in each molecule, wherein the polyoxyalkylene polymer includes an impurity double metal cyanide complex mixed therein, and wherein the polyoxyalkylene polymer has not been treated with a metal-coordinating compound; and adding to the polyoxyalkylene polymer a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule and a hydrosilylation catalyst to thereby carry out a hydrosilylation reaction, wherein the hydrosilyation reaction is performed in an absence of a metal-coordinating compound. | 03-07-2013 |
Bijay S. Saha, Chandler, AZ US
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20110084388 | REDUCING UNDERFILL KEEP OUT ZONE ON SUBSTRATE USED IN ELECTRONIC DEVICE PROCESSING - Electronic devices and methods for fabricating electronic devices are described. One method includes providing a substrate with a die attach area, and forming a layer on the substrate outside of the die attach area. The layer may be formed from a fluoropolymer material. The method also includes coupling a die to the substrate in the die attach area, wherein a gap remains between the die and the die attach area. The method also includes placing an underfill material in the gap and adjacent to the layer on the substrate. Examples of fluoropolymer materials which may be used include polytetrafluoroethylene (PTFE) and perfluoroalkoxy polymer resin (PFA). Other embodiments are described and claimed. | 04-14-2011 |
Chandan K. Saha, W. Bloomfield, MI US
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20080293564 | MULLITE BODIES AND METHODS OF FORMING MULLITE BODIES - A method of forming a porous mullite composition of acicular mullite grains having improved properties is described, where the mullite is formed at some time in the presence of a fluorine containing gas. For example, it has been discovered that improved properties may result from heating the mullite to a high temperature in an atmosphere selected from the group consisting of water vapor, oxygen, an inert gas or mixtures thereof or forming the mullite composition from precursors having an Al/Si ratio of at most 2.95. | 11-27-2008 |
Chandan K. Saha, Franklin, MI US
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20140001143 | DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS | 01-02-2014 |
Chandan Kumar Saha, Franklin, MI US
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20130171456 | Glass Articles With Low-Friction Coatings - Low-friction coatings and glass articles with low-friction coatings are disclosed. According to one embodiment, a coated glass article may include a glass body comprising a first surface and a low-friction coating positioned on at least a portion of the first surface of the glass body. The low-friction coating may include a polymer chemical composition. The coated glass article may be thermally stable at a temperature of at least about 260° C. for 30 minutes. A light transmission through the coated glass article may be greater than or equal to about 55% of a light transmission through an uncoated glass article for wavelengths from about 400 nm to about 700 nm. The low-friction coating may have a mass loss of less than about 5% of its mass when heated from a temperature of 150° C. to 350° C. at a ramp rate of about 10° C./minute. | 07-04-2013 |
20130224407 | Glass Articles With Low-Friction Coatings - Low-friction coatings and glass articles with low-friction coatings are disclosed. According to one embodiment, a coated glass article may include a glass body comprising a first surface and a low-friction coating positioned on at least a portion of the first surface of the glass body. The low-friction coating may include a polymer chemical composition. The coated glass article may be thermally stable at a temperature of at least about 260° C. for 30 minutes. A light transmission through the coated glass article may be greater than or equal to about 55% of a light transmission through an uncoated glass article for wavelengths from about 400 nm to about 700 nm. The low-friction coating may have a mass loss of less than about 5% of its mass when heated from a temperature of 150° C. to 350° C. at a ramp rate of about 10° C./minute. | 08-29-2013 |
20140001076 | DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS | 01-02-2014 |
20140069886 | DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS - Delamination resistant glass containers with heat-tolerant coatings are disclosed. In one embodiment, a glass container may include a glass body having an interior surface, an exterior surface and a wall thickness extending from the exterior surface to the interior surface. At least the interior surface of the glass body is delamination resistant. The glass container may further include a heat-tolerant coating positioned on at least a portion of the exterior surface of the glass body. The heat-tolerant coating may be thermally stable at temperatures greater than or equal to 260° C. for 30 minutes. | 03-13-2014 |
20140106141 | LAMINATE ARTICLES WITH MODERATE ADHESION AND RETAINED STRENGTH - One or more aspects of the disclosure pertain to an article including a film disposed on a glass substrate, which may be strengthened, where the interface between the film and the glass substrate is modified, such that the article has an improved average flexural strength, and the film retains key functional properties for its application. Some key functional properties of the film include optical, electrical and/or mechanical properties. In one or more embodiments, interface exhibits the effective adhesion energy is about less than about 4 J/m | 04-17-2014 |
20140106146 | ARTICLES HAVING RETAINED STRENGTH - One or more aspects of the disclosure pertain to an article including a film disposed on a glass substrate, which may be strengthened, where the interface between the film and the glass substrate is modified, such that the article retains its average flexural strength, and the film retains key functional properties for its application. Some key functional properties of the film include optical, electrical and/or mechanical properties. The bridging of a crack from one of the film or the glass substrate into the other of the film or the glass substrate can be prevented by inserting a crack mitigating layer between the glass substrate and the film. | 04-17-2014 |
20140220327 | Glass Articles Having Films with Moderate Adhesion and Retained Strength - One or more aspects of the disclosure pertain to an article including a film disposed on a glass substrate, which may be strengthened, where the interface between the film and the glass substrate is modified, such that the article has an improved average flexural strength, and the film retains key functional properties for its application. Some key functional properties of the film include optical, electrical and/or mechanical properties. In one or more embodiments, the interface exhibits an effective adhesion energy of about less than about 4 J/m | 08-07-2014 |
20150074974 | ION-EXCHANGED GLASS OF HIGH SURFACE COMPRESSION AND SHALLOW DEPTH OFLAYER WITH HIGH RESISTANCE TO RADIAL CRACK FORMATION FROM VICKERSINDENTATION - Disclosed are alkali aluminosilicate glasses having unexpected resistance to indentation cracking. The glasses obtain this high resistance as a result of a high level of surface compression accompanied by a shallow depth of layer. The advantaged glasses show greater resistance to radial crack formation from Vickers indentation than glasses with the same compressive stress, but higher depths of layer. | 03-19-2015 |
Debanjan Saha, Westchester County, NY US
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20100031095 | METHOD AND APPARATUS FOR ENHANCING TICKETING SYSTEM IN A SERVICE MANAGEMENT PROCESS FOR EFFICIENT PROBLEM RESOLULTION - Problem ticket usage is improved by adding dynamic information to the ticket or using dynamic information to prompt the user or customer for additional information. Two categories of dynamic information are used. In the case where an initial problem ticket involves identification of a problem component the dynamic information is derived from abnormal status of related components, such as components which support the problem component. In the case where an initial problem ticket involves problem symptom information, data is derived from resolved problem tickets by identifying important words or concepts which are stored in connection with the particular symptom. When later problem tickets having the same symptom are identified the related important words or concepts are either added to the problem ticket or are used to prompt customers or users for additional information. A system implementing an embodiment of the invention is also described. | 02-04-2010 |
Deba P. Saha, Nutley, NJ US
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20080311623 | Plasmid system for multigene expression - The present invention provides a plasmid system which facilitates the construction of a single amplifiable plasmid that, having the potential to accommodate many independent expression cassettes, has the ability to express multi-subunit complex proteins such as antibodies and receptors. | 12-18-2008 |
20100120090 | MAMMALIAN EXPRESSION VECTOR pUHAB - The present invention relates to the construction and utilization of a new mammalian expression vector that contains a unique multiple cloning site (MCS), designated pUHAB. The pUHAB vector comprises a high copy replication origin (ColE1), a drug resistance gene (TK-Hygromycin), and a human cytomegalovirus promoter operably associated with a unique intron (hCMV/intron). Further, pUHAB comprises a selectable marker conferring resistance to kanamycin in bacterial cells, and a phage f1(+) region. pUHAB can be used to transiently or stably express cloned genes when transfected into mammalian cells. The invention also encompasses kits and host cells and cell lines comprising pUHAB, and methods of producing a recombinant protein using pUHAB. | 05-13-2010 |
20110217695 | BETAG1-IgG INTRON FOR ENHANCED ANTI-IGF1R EXPRESSON - The present invention provides polynucleotides for enhanced expression of a target gene such as an immunoglobulin. Methods of expressing a target gene using the polynucleotides of the invention are also covered. | 09-08-2011 |
20120040402 | PLASMID SYSTEM FOR MULTIGENE EXPRESSION - The present invention provides a plasmid system which facilitates the construction of a single amplifiable plasmid that, having the potential to accommodate many independent expression cassettes, has the ability to express multi-subunit complex proteins such as antibodies and receptors. | 02-16-2012 |
20120142056 | MAMMALIAN EXPRESSION VECTOR pUHAB - The present invention relates to the construction and utilization of a new mammalian expression vector that contains a unique multiple cloning site (MCS), designated pUHAB. The pUHAB vector comprises a high copy replication origin (ColE1), a drug resistance gene (TK-Hygromycin), and a human cytomegalovirus promoter operably associated with a unique intron (hCMV/intron). Further, pUHAB comprises a selectable marker conferring resistance to kanamycin in bacterial cells, and a phage f1(+) region. pUHAB can be used to transiently or stably express cloned genes when transfected into mammalian cells. The invention also encompasses kits and host cells and cell lines comprising pUHAB, and methods of producing a recombinant protein using pUHAB. | 06-07-2012 |
20140030760 | PAVEC - This application provides, in part, pAVEC plasmids and methods of use of such plasmids for the production of polypeptides such as immunoglobulins as well as the generation of recombined versions of such plasmids which contain polynucleotides encoding such polypeptides. | 01-30-2014 |
20150197772 | MAMMALIAN EXPRESSION VECTOR pUHAB - The present invention relates to the construction and utilization of a new mammalian expression vector that contains a unique multiple cloning site (MCS), designated pUHAB. The pUHAB vector comprises a high copy replication origin (ColE1), a drug resistance gene (TK-Hygromycin), and a human cytomegalovirus promoter operably associated with a unique intron (hCMV/intron). Further, pUHAB comprises a selectable marker conferring resistance to kanamycin in bacterial cells, and a phage f1(+) region. pUHAB can be used to transiently or stably express cloned genes when transfected into mammalian cells. The invention also encompasses kits and host cells and cell lines comprising pUHAB, and methods of producing a recombinant protein using pUHAB. | 07-16-2015 |
Deepak Saha, Watervliet, NY US
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20140093377 | EXTRUDED ROTOR, A STEAM TURBINE HAVING AN EXTRUDED ROTOR AND A METHOD FOR PRODUCING AN EXTRUDED ROTOR - A steam turbine, a rotor and a method for making an extruded rotor are disclosed as having a rotor bore formed of an extruded high temperature alloy. The method includes providing a high temperature alloy, melting the high temperature alloy, extruding the high temperature alloy to form a bore, and forming the bore into a rotor. | 04-03-2014 |
20150017462 | Cast CrMoV Steel Alloys and the Method of Formation and Use in Turbines Thereof - A cast alloy is generally provided, along with methods of forming the cast alloy and components constructed from the cast alloy (e.g., stationary components of a turbine). The cast alloy can include, by weight, 0.12% to 0.20% carbon, 0.50% to 0.90% manganese, 0.25% to 0.60% silicon, 0.10% to 0.50% nickel, 1.15% to 1.50% chromium, 0.90% to 1.50% molybdenum, 0.70% to 0.80% vanadium, 0.0075% to 0.060% titanium, 0.008% to 0.012% boron, the balance iron, optionally low levels of other alloying constituents, and incidental impurities. | 01-15-2015 |
Deepak Saha, Guilderland, NY US
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20090250185 | METHODS FOR CASTING STAINLESS STEEL AND ARTICLES PREPARED THEREFROM - A process for casting stainless steel including forming an erodable casting mold, delivering molten stainless steel into the erodable mold, contacting the erodable mold with a solvent, cooling the molten stainless steel to at least partially solidify the stainless steel and form a casting. Stainless steel castings are also provided. | 10-08-2009 |
20100263821 | SUPER-ALLOY AND STAINLESS STEEL CASTING METHOD - Embodiments of the present invention include a method for producing a component that includes melting a super-alloy or stainless steel alloy and transferring the melted alloy to a mold. The mold is mechanically vibrated while the melted alloy solidifies. The component then is removed from the mold. | 10-21-2010 |
20110070088 | STEAM TURBINE ROTOR AND ALLOY THEREFOR - An alloy suitable for use in a rotor, such as one or more regions of a steam turbine rotor, as well as a forged rotor formed with the alloy. The alloy consists of, by weight, 0.20 to 0.30% carbon, 0.80 to 1.5% chromium, 0.80 to 1.5% molybdenum, 0.50 to 0.90% vanadium, 0.30 to 0.80% nickel, 0.05 to 0.15% titanium, 0.20 to 1.0% manganese, and 0.005 to 0.012% boron, the balance iron, optionally low levels of other alloying constituents, and incidental impurities. | 03-24-2011 |
Dhanonjoy Saha, Matthews, NC US
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20110092589 | Treatment of Inflammatory Conditions and Diseases with Metal-Thiols - The present invention provides a method for the treatment of a disease or disorder related to an inflammatory condition comprising administering to a patient in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a metal and a thiol. In particular, embodiments of the present invention are directed towards methods of treating inflammatory conditions that are associated with elevated levels of free TNFα. In one embodiment, the present invention can be used to treat and/or ameliorate the effects of a wide variety of diseases or disorders related to an inflammatory condition including one or more of the following inflammation related diseases/disorders: arthritis, rheumatoid arthritis, asthma, psoriasis, systemic lupus erythematosus, inflammatory bowel syndrome, chronic obstructive respiratory diseases (COPD), fibromyalgia and the neurological diseases and disorders multiple sclerosis, Alzheimer's disease, Parkinson's disease, Huntington's disease, vascular dementia, epilepsy, migraines, stroke and trauma. | 04-21-2011 |
Gobinda Saha, Pittsburgh, PA US
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20110135850 | PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION - The present disclosure provides for new photoalignment (co)polymer materials which demonstrate improved adhesion to a substrate. The (co)polymeric structure includes at least one photochemically active chromophore and at least one adhesion promoter group. Articles of manufacture, optical elements, ophthalmic elements and liquid crystal cells which include at least one photoalignment layer made from the photoalignment (co)polymer materials and methods for formation are also disclosed. | 06-09-2011 |
Jayanta Saha, Apex, NC US
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20080293648 | Compositions and Methods for Cancer Treatment - This invention provides methods, novel formulations and kits to reduce the toxicity of anticancer drugs. Disclosed are therapeutics and treatment methods employing anticancer drags that exhibit a known toxicity, including, for example, adriamycin, campthothecin, and the like, chemically linked to a phosphonoformic acid partial ester resulting in a novel formulation that significantly decreases drug-related toxicity, enhances synergy with other chemotherapeutic drugs and provides increased efficacy against drug-resistant cancers. | 11-27-2008 |
20100227831 | COMPOSITIONS AND METHODS FOR CANCER TREATMENT - A novel composition of a phosphonoformic acid partial ester chemically linked to an anticancer compound of the general formula: | 09-09-2010 |
Kamal K. Saha, Newark, DE US
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20130186758 | CURRENT-CARRYING NANOWIRE HAVING A NANOPORE FOR HIGH-SENSITIVITY DETECTION AND ANALYSIS OF BIOMOLECULES - Disclosed are devices that feature nanopores formed in graphene sheets, such as graphene ribbons. The graphene sheets include an edge irregularity, such as a zig-zag configuration, a chiral edge, or an armchair-configuration edge, which edges confer on the devices the ability to discriminate between different subunits of a macromolecule translocated through the nanpore. The disclosed devices and methods have application to DNA sequencing and analysis, among other applications. | 07-25-2013 |
Krishanu Saha, Cambridge, MA US
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20100273259 | SUBSTRATES AND METHODS FOR CULTURING STEM CELLS - The present disclosure provides a device and a cell culture system comprising a substrate that generates significant chemical ion signatures adapted for culturing stem cells. This disclosure further provides unique surface properties, such as surface wettability, along with defined polymer microspot environments in an array, for effectively supporting the propagation and differentiation of human pluripotent stem cells in vitro. Methods of culturing, maintenance, differentiating stem cells as well as reprogramming somatic cells into stem cells using the device and the cell culture system with the suitable substrates, along with suitable culture media, are also provided. | 10-28-2010 |
20110046038 | Polypeptide-Polymer Conjugates and Methods of Use Thereof - The present invention provides polypeptide-polymer conjugates. A subject polypeptide-polymer conjugate is useful in a variety of applications, cations, which are also provided. | 02-24-2011 |
Krishnendu Saha, Philadelphia, PA US
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20100145194 | HISTOGRAM-BASED ANALYSIS METHOD FOR THE DETECTION AND DIAGNOSIS OF NEURODEGENERATIVE DISEASES - An analysis method using histograms derived from positron emission tomography (PET) or single photon emission tomography (SPECT) images of the brain, which utilizes radiopharmaceuticals for the detection and diagnosis of pathological targets associated with neurodegenerative disease in a patient is provided. | 06-10-2010 |
Mainak Saha, Edina, MN US
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20110190784 | CATHETER WITH REMOVABLE SHAPING SKELETON AND METHODS OF USING AND MAKING SAME - A delivery tool for the delivery of an implantable medical lead includes a longitudinally extending tubular body and a longitudinally extending skeleton. The longitudinally extending tubular body includes a distal end, a proximal end, a tubular body segment proximal the distal end, a first lumen extending between the proximal and distal ends, and a second lumen. The first lumen is configured to receive therein the implantable medical lead. The longitudinally extending skeleton is received in the second lumen and includes a distal end, a proximal end, and a portion near the distal end that biases into a non-linear shape. The portion of the skeleton causes the tubular body segment to generally assume the non-linear shape. The skeleton is withdrawable from the second lumen. The proximal ends of the skeleton and the tubular body may have a mechanical engagement arrangement that mechanically engages the proximal ends together in a manner that may be released to allow the proximal ends to be separated from each other. Upon withdrawal of the skeleton from the second lumen, the tubular body segment is free to assume a shape different from the non-linear shape. | 08-04-2011 |
Manasi Saha, Apex, NC US
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20080202259 | Method For Determining Pesticide Residues in Soil or Plant Material - The present invention relates to a method for determining pesticide residues in the soil or plant material, which comprises processing a soil or plant material sample to a fine powder, converting the powder or a portion thereof into a form accessible for determining the analyte, and determining the analyte. The invention is thus concerned with environmental analysis and in particular environmental trace analysis. The method advantageously allows the use of microextraction techniques and thus a high sample throughput. | 08-28-2008 |
Pamela Saha, Wellsvile, NY US
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20090091046 | Polariscope toy and ornament with accompanying photoelastic and/or photoplastic devices - A variety of toy polariscopes are simpler in design and less costly than precision instruments used in scientific research and stress analysis of materials and structures. The toy polariscopes are designed for a variety of objects that may exhibit photoelastic properties such as glass, plastic, Plexiglas, gel candle material and other gels, and even edible photoelastic objects. They are specially designed for objects of various sizes with a variety of purposes such as objects to enhance learning in a variety of conditions and experiences. Special objects are designed to go with the toy polariscopes such as edible and inedible photoelastic objects, photoelastic candle material, a variety of photoelastic/photoplastic stands capable of a variety of displays in interaction with other designed photoelastic objects capable of a variety of interaction and displays. Other optical phenomena may also be observed. | 04-09-2009 |
Pamela Saha, Brooklyn, NY US
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20120077152 | Cellophane cut out kits for optical art - One or more transparent or translucent sheets of cellophane are folded and cuts are made to create symmetric patterns and designs. The cellophane creates diffraction, refraction, interference, and reflection pattern of light that become strikingly visible when viewed under polarized light. The cellophane patterns and designs are placed on top of one another such that the holes in the overlapping sheets cause a variation in the path of light traveling through the layers of the cellophane, creating beautiful and varied optical patterns of light that change with the placement of the layers of cellophane and with variation of the angle of polarized light for a kaleidoscope effect. The cellophane is viewed against the backdrop of a blue sky to provide a source of polarized light. Placing the cellophane on glossy black cardboard brings out the prismatic colors created by light refraction and reflection | 03-29-2012 |
20120206803 | Optical art kits and puppets with origami cellophane, adhesive tape, photoelastic models, polariscopes, knitting, and diffraction films - Kits for creating optical art come with precut cellophane and/or adhesive tape and instructions for folding the cellophane into origami structures having desired optical qualities and/or applying the adhesive tape in a layered fashion to achieve desired optical properties. Adhesive tape or cellophane cut into specific decorative shapes is provided on a tape roll or sheet for easily peeling it off and applying it to create optical art. Tools are provided for cutting, punching out, or otherwise shaping provided cellophane and/or tape. Instruments such as polarizing films, light sources, and/or polarizing glasses are provided for viewing the optical art under polarized light. These instruments may include toy polariscopes, particularly having an ergonomic design. Diffusion lenses are provided to enhance the viewing experience. Photoelastic models and puppets may also be provided. | 08-16-2012 |
20130115339 | Polariscope toy and ornament with accompanying photoelastic and/or photoplastic devices - A variety of toy polariscopes are simpler in design and less costly than precision instruments used in scientific research and stress analysis of materials and structures. The toy polariscopes are designed for a variety of objects that may exhibit photoelastic properties such as glass, plastic, Plexiglas, gel candle material and other gels, and even edible photoelastic objects. They are specially designed for objects of various sizes with a variety of purposes such as objects to enhance learning in a variety of conditions and experiences. Special objects are designed to go with the toy polariscopes such as edible and inedible photoelastic objects, photoelastic candle material, a variety of photoelastic/photoplastic stands capable of a variety of displays in interaction with other designed photoelastic objects capable of a variety of interaction and displays. Other optical phenomena may also be observed. | 05-09-2013 |
20130287891 | DISPOSABLE COMBINED SQUEEZER/STIRRER/DISPENSER/BREWER DEVICE - A disposable packaging form is provided for brewed, hot drinks. The invention allows a user to brew the hot drink, squeeze out the brewed contents, and stir the contents of the hot drink. Each action can be performed multiple times before disposal. In some embodiments, the device of the present invention dispenses sweeteners, creamers, flavorings and condiments. The present invention frees the user of the inconvenience of having to collect, wash, or dispose of the stirrers, squeezers and bags of the hot drink individually. | 10-31-2013 |
Pamela Saha, Wellsville, NY US
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20100015292 | Disposable combined squeezer/stirrer/dispenser/brewer device - A disposable packaging form is provided for brewed, hot drinks. The invention allows a user to brew the hot drink, squeeze out the brewed contents, and stir the contents of the hot drink. Each action can be performed multiple times before disposal. In some embodiments, the device of the present invention dispenses sweeteners, creamers, flavorings and condiments. The present invention frees the user of the inconvenience of having to collect, wash, or dispose of the stirrers, squeezers and bags of the hot drink individually. | 01-21-2010 |
Partha Saha, Pittsburgh, PA US
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20140097277 | BIODEGRADABLE IRON-CONTAINING COMPOSITIONS, METHODS OF PREPARING AND APPLICATIONS THEREFOR - The invention relates to biodegradable iron alloy-containing compositions for use in preparing medical devices. In addition, biodegradable crystalline and amorphous compositions of the invention exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions include elemental iron and one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique. The resulting compositions and the devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular. | 04-10-2014 |
20140248288 | BIODEGRADABLE METAL ALLOYS - The invention relates to biodegradable, metal alloy-containing compositions, methods for their preparation and applications for their use. The compositions include magnesium and other components, such as yttrium, calcium, silver, cerium, and zirconium; or zinc, silver, cerium, and zirconium; or aluminum, zinc, calcium, manganese, silver, yttrium; or strontium, calcium, zinc. The compositions are prepared by vacuum induction/crucible melting together the components and casting the melted mixture in a preheated mild steel/copper mold. In certain embodiments, the compositions of the invention are particularly useful for forming medical devices for implantation into a body of a patient. | 09-04-2014 |
Pinaki Saha, Chicago, IL US
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20100153848 | INTEGRATED BRANDING, SOCIAL BOOKMARKING, AND AGGREGATION SYSTEM FOR MEDIA CONTENT - A system enables user generated content (UGC) and data (collectively metadata) to be associated with playable media content in a GUI. A skin (metadata and GUI) overlays the media content and includes a set of markers associated with the selected media content, the markers with at least one of an elapsed time and a frame of the selected playable media content and including metatags relevant to the content of the media at the elapsed time or frame. The system includes a social networking and sharing platform and provides layers of meta-information that can be added, deleted, or edited without altering the original content. The system enables the tagging of objects within content and allows these objects to be matched to any category of interest, and allows sharing of such tags. The system enables ‘search & discovery’ by sorting and matching labels (e.g., title & description) and works with still image media, audio, or video. | 06-17-2010 |
Pradip Saha, Wilmington, NC US
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20090016479 | FEEDWATER TEMPERATURE CONTROL METHODS AND SYSTEMS - In various embodiments, a system for controlling the power level of a natural circulation boiling water nuclear reactor (NCBWR) is provided. In various embodiments, the system includes a heating subsystem for heating feedwater flowing into an annulus of a NCBWR to increase the temperature of recirculation water flowing through the core above a predetermined recirculation water operating temperature. Additionally the system includes a temperature sensor operable to sense the temperature of the feedwater flowing into the annulus. The temperature sensor is communicatively connected to a temperature controller operable to command the heating subsystem to increase the temperature of the feedwater flowing into the annulus to a requested temperature above a predetermined operating temperature of the feedwater flowing into the annulus. By increasing the temperature of the feedwater flowing into the annulus, the temperature of the recirculation water is increased above the predetermined recirculation water operating temperature causing a reduction in the power level generated by the NCBWR core. | 01-15-2009 |
20150200021 | PASSIVE SHUTDOWN SYSTEM AND METHOD OF OPERATING A LIQUID METAL COOLED REACTOR USING THE SAME - A passive shutdown system for a liquid metal cooled reactor may include a tube and a neutron absorber within the tube. The tube may be configured to extend through a core of the liquid metal cooled reactor. The tube has an upper end and a lower end. The tube defines a flow path for a liquid metal coolant. The neutron absorber is a mobile structure configured to partially obstruct a flow of the liquid metal coolant within the flow path. A method of operating a liquid metal cooled reactor may involve the use of the passive shutdown system. | 07-16-2015 |
Punam Kumar Saha, Iowa City, IA US
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20090208081 | Apparatus and method for computing regional statistical distribution over a mean atomic space - The present invention is an apparatus and method for computing regional statistical distributions or characteristics of one or more quantitative measures over a mean anatomic space for one or more predefined populations and uses this statistical distributions/characteristics to study, research or understand the regional response of a disease or a treatment process and to regionally assess clinical status in patient data from an unknown population for diagnostic purposes. | 08-20-2009 |
Rajarshi Saha, Atlanta, GA US
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20120219793 | POLYHEDRAL OLIGOMERIC SILSESQUIOXANE COMPOSITIONS, METHODS OF USING THESE COMPOSITIONS, AND STRUCTURES INCLUDING THESE COMPOSITIONS - Embodiments of the present disclosure include functionalized polyhedral oligomeric silsesquioxane compositions or mixtures, methods of using functionalized polyhedral oligomeric silsesquioxane compositions, structures including functionalized polyhedral oligomeric silsesquioxane, and the like. | 08-30-2012 |
20130341736 | Packaging Compatible Wafer Level Capping of MEMS Devices - This invention discloses and claims a cost-effective, wafer-level package process for microelectromechanical devices (MEMS). Specifically, the movable part of MEMS device is encapsulated and protected while in wafer form so that commodity, lead-frame packaging can be used. An overcoat polymer, such as, epoxycyclohexyl polyhedral oligomeric silsesquioxanes (EPOSS) has been used as a mask material to pattern the sacrificial polymer as well as overcoat the air-cavity. The resulting air-cavities are clean, debris-free, and robust. The cavities have substantial strength to withstand molding pressures during lead-frame packaging of the MEMS devices. A wide range of cavities from 20 μm×400 μm to 300 μm×400 μm have been fabricated and shown to be mechanically stable. These could potentially house MEMS devices over a wide range of sizes. The strength of the cavities has been investigated using nano-indentation and modeled using analytical and finite element techniques. Capacitive resonators packaged using this protocol have shown clean sensing electrodes and good functionality. | 12-26-2013 |
Saikat Saha, Waukesha, WI US
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20130157865 | SYSTEM FOR MAGNETIC FIELD DISTORTION COMPENSATION AND METHOD OF MAKING SAME - A system and method for magnetic field distortion compensation includes a cryostat for a magnetic resonance imaging (MRI) system. The cryostat includes a vacuum casing having a vacuum therein. A cryogen vessel is disposed within the casing, the vessel having a coolant therein. A thermal shield is disposed between the vacuum casing and the cryogen vessel. An eddy current compensation assembly is disposed within the casing. The eddy current compensation assembly includes a plurality of electrically conductive loops formed on one of the vacuum casing, the cryogen vessel, and the thermal shield and constructed to mitigate vibration-induced eddy currents in the MRI system. | 06-20-2013 |
20140187909 | WHOLE BODY RF COIL FOR PET-MR SYSTEM - A PET-MR apparatus includes an MR imaging system having an RF coil former having inner and outer surfaces, an RF shield formed about the outer surface of the RF coil former, and an RF coil positioned on the inner surface of the RF coil former. The PET-MR apparatus also includes a PET system having a detector array positioned to encircle the bore to acquire PET emissions of the subject of interest and a plurality of RF power cables to provide power to the RF coil. The RF coil of the PET-MR apparatus comprises an RF body coil including a pair of end rings and a plurality of rungs extending between the end rings, wherein the plurality of RF power cables are coupled to one of the pair of end rings, along an outer edge of the one end ring distal from the plurality of rungs. | 07-03-2014 |
Saikat Saha, Florence, SC US
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20080315879 | SYSTEM AND APPARATUS FOR ELECTROMAGNETIC NOISE DETECTION IN AN MR IMAGING SCANNER ENVIRONMENT - A system for detecting electromagnetic noise in a magnetic resonance imaging (MRI) scanner environment includes an antenna configured to detect electromagnetic noise. The antenna includes a first conducting loop and a second conducting loop oriented perpendicularly to the first conducting loop. The system also includes a noise correction system coupled to the antenna and configured to receive noise signals from the antenna. | 12-25-2008 |
20100033185 | RF COIL AND APPARATUS TO REDUCE ACOUSTIC NOISE IN AN MRI SYSTEM - A radio frequency (RF) coil for a magnetic resonance imaging (MRI) system includes a first end ring section containing a plurality of openings and a second end ring section containing a plurality of openings. A plurality of rungs is disposed between the first end ring section and the second end ring section. Each rung has a first end connected to the first end ring section and a second end connected to the second end ring section. Each rung can also include a plurality of openings. The openings in the end rings and rungs reduces eddy currents and improves RF performance of the RF coil. | 02-11-2010 |
20100102817 | HYBRID BIRDCAGE-TEM RADIO FREQUENCY (RF) COIL FOR MULTINUCLEAR MRI/MRS - A radio frequency (RF) coil for a magnetic resonance imaging system includes a plurality of rungs disposed around a volume and a first end ring connected to a first end of the plurality of rungs. The first end ring has a first plurality of birdcage mode tuning capacitors and a first plurality of RF traps. The RF coil also includes a second end ring connected to a second end of the plurality of rungs. The second end ring has a second plurality of birdcage mode tuning capacitors and a second plurality of RF traps. An RF shield is disposed around the plurality of rungs, the first end ring and the second end ring. The RF coil also includes a plurality of transverse electromagnetic (TEM) mode tuning capacitors, where each TEM mode tuning capacitor coupled to one of the plurality of rungs. An RF trap is connected to each of the plurality of TEM mode tuning capacitors. | 04-29-2010 |
20100141258 | RADIO FREQUENCY (RF) COIL AND APPARATUS - A radio frequency (RF) coil for a magnetic resonance imaging (MRI) system includes a plurality of rungs. Each rung includes a plurality of wires positioned parallel to one another. Each wire has a circular cross section and an insulating material disposed around an outside surface of the wire. Using wires with a circular cross-section reduces the eddy currents produced on a rung. As a result, the amount of eddy current produced heating, vibration and acoustic noise is reduced. The plurality of wires also enables a more uniform current distribution along the width of each rung that in turn produces a more uniform excitation field (B | 06-10-2010 |
20120062231 | RADIO FREQUENCY (RF) COIL FOR MRI HAVING HIGH THERMAL CONDUCTIVITY - An MRI apparatus and method is disclosed comprising a magnetic resonance imaging (MRI) system having a plurality of gradient coils positioned about a bore of a magnet, and an RF transceiver system and an RF switch controlled by a pulse module to transmit RF signals to an RF coil assembly to acquire MR images. The RF coil assembly comprises an RF tube, a plurality of electrically conductive members disposed around the RF tube and configured to transmit RF excitation pulses, a plurality of electrical components coupled to the electrically conductive members, and at least one thermally conductive substrate mounted upon the RF tube, wherein one of the plurality of electrically conductive members and the plurality of electrical components is mounted to the at least one thermally conductive substrate and is in thermal contact therewith. | 03-15-2012 |
20120146643 | RADIO FREQUENCY COIL AND APPARATUS - A radio frequency (RF) coil for a magnetic resonance imaging (MRI) system includes a first end ring, a second end ring, and a plurality of rungs electrically coupled between the first and second end rings, each rung including a first rung portion formed from a plurality of conductors and a second rung portion formed from a single solid conductor. A resonance assembly for a magnetic resonance imaging (MRI) system and an MRI imaging system are also described herein. | 06-14-2012 |
20120229138 | APPARATUS AND METHOD TO REDUCE NOISE IN MAGNETIC RESONANCE IMAGING SYSTEMS - An apparatus and method to reduce noise in magnetic resonance imaging (MRI) systems are provided. One MRI system includes a gantry having a bore therethrough and at least one radio frequency (RF) coil supported by the gantry for imaging an object within the bore. The MRI system also includes a vacuum space between the at least one RF coil and the bore. | 09-13-2012 |
20120293173 | RF BODY COIL FOR REDUCED ACOUSTIC NOISE IN AN MR SYSTEM - An RF body coil having enhanced acoustic deadening properties for an MR scanning apparatus is disclosed. The RF body coil includes an RF support form and RF electronics affixed to the RF support form, with the RF electronics comprising a plurality of RF legs. The RF support form further includes an inner structural layer, an outer structural layer, and a middle layer sandwiched between the inner structural layer and the outer structural layer, the middle layer comprising a layer of viscoelastic material configured to increase the mechanical damping of the RF body coil so as to reduce RF body coil vibration. | 11-22-2012 |
Sam Saha, Milwaukee, WI US
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20140366164 | REMOTELY ACTUATED DISPLAY SYSTEM AND RELATED METHODS - A remotely articulated display system for displaying an electronic device has a locking mechanism that is controlled by software installed on the electronic device. The software installed on the electronic device requires a user to supply an authorization input to lock and unlock the electronic device from the display system. Related methods are also disclosed herein, e.g., methods of remotely locking a display via software stored on the device being displayed, methods of locking a display via a multi-stage lock, etc. | 12-11-2014 |
Sanjoy K. Saha, Chandler, AZ US
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20130299133 | HIGH PERFORMANCE TRANSIENT UNIFORM COOLING SOLUTION FOR THERMAL COMPRESSION BONDING PROCESS - Various embodiments of thermal compression bonding transient cooling solutions are described. Those embodiments include a an array of vertically separated micro channels coupled to a heater surface, wherein every outlet micro channel comprises two adjacent inlet micro channel, and wherein an inlet and outlet manifold are coupled to the array of micro channels, and wherein the heater surface and the micro channels are coupled within the same block. | 11-14-2013 |
Sanjoy Kumar Saha, Chandler, AZ US
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20100182751 | Heat Sink - A system for removing heat from an electronic component associated with an information handling system is disclosed. The system may comprise a mass providing a heat sink to the electronic component and a set of extended surfaces for transferring heat from the mass. The set of extended surfaces may define a primary flow direction for a cooling fluid. A first subset of the set of extended surfaces may have a first length measured in the primary flow direction. A second subset of the set of extended surfaces may have a second length measured in the primary flow direction. Each of the first and second subsets of extended surfaces may include one or more extended surfaces. The second subset of extended surfaces may be generally proximate the hotspot of the electronic component. The second length may be less than the first length such that the flow rate of the cooling fluid through the second subset of extended surfaces is greater than a flow rate of the cooling fluid through the first subset of extended surfaces. | 07-22-2010 |
Sanjoy Kumar Saha, Round Rock, TX US
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20090279246 | Global Heat Sink Carrier for Electronics Components - A system for mounting an electronic component associated with an information handling system is disclosed. The system may comprise a carrier configured to carry an electronic component and a caddy configured to mount the carrier and the electronic component to a structure of the information handling system. The carrier may include a mass providing a heat sink to the electronic component and one or more fins for transferring heat from the mass. The carrier and the caddy may operate in conjunction as a damper to attenuate vibration. | 11-12-2009 |
Saurabh Saha, Leawood, KS US
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20140134179 | TEM8 ANTIBODIES, CONJUGATES THEREOF, AND THEIR USE - Antibodies that specifically bind TEM8 protein, and conjugates thereof, are disclosed herein. In some examples the conjugates and antibodies are useful for methods of detecting and treating pathogenic angiogenesis. In other examples the conjugates and antibodies are useful for methods of detecting and treating cancer. In additional examples, the conjugates and antibodies are useful for methods of decreasing binding of Anthrax protective antigen to a cell. | 05-15-2014 |
20140235556 | COMPOSITIONS AND METHODS OF TREATING GLIOMAS - The present invention provides, inter alia, methods for treating or ameliorating the effects of a glioma. Methods of this invention include administering to a subject in need thereof an effective amount of a first active agent, such as e.g., an angiotensin receptor blocker, an antifungal agent, a bisphosphonate, an oxytocin inhibitor, an interleukin-1 (IL-1) inhibitor, a cyclooxygenase inhibitor, an α2δ voltage-dependent calcium channel (VDCC) inhibitor, a dihydroorotate dehydrogenase inhibitor, a calcium channel blocker, a renal sodium-chloride symporter inhibitor, an a2 adrenergic agonist, a phenothiazine antipsychotic, a calcineurin inhibitor, a 5-HT agonist, an angiotensin-converting enzyme (ACE) inhibitor, a direct rennin inhibitor, or combinations thereof, and a second active agent, which is a chemotherapeutic agent. Compositions for treating or ameliorating the effects of a glioma are also provided. | 08-21-2014 |
Saurabh Saha, Wellesley Hills, MA US
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20150018360 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS - The present invention provides, inter alia, compositions containing enantiomerically pure (R)(+)-amisulpride or enantiomerically pure (R)(+)-sulpiride, optionally with dopamine receptor modulators. The present invention also provides compositions containing racemic (RS)-amisulpride or (RS)-sulpiride in combination with dopamine receptor modulators. Methods for preventing, treating, or ameliorating the effects of a metabolic disorder or key element thereof, for modulating blood glucose levels, and for preventing, treating, or ameliorating the effects of diabetes in a subject are also provided. Additionally, the present invention provides methods for counter-acting the dopamine antagonist activity of (S)-amisulpride in racemic (RS)-amisulpride, or the dopamine antagonist activity of (S)-sulpiride in racemic (RS)-sulpiride, administered to a subject to prevent, treat, or ameliorate the effects of a metabolic disorder. | 01-15-2015 |
Shibani Saha, Lombard, IL US
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20140127975 | Robotic Surface Treatment Device - A robotic surface treatment device includes at least two wheels, at least two electric motors, wherein one electric motor is connected to one corresponding wheel via a motor shaft, at least two treatment pads, wherein at least one treatment pad is attached to a bottom surface of a corresponding wheel, a main controller positioned on top of and in connection with drive controllers positioned on top of each electric motor, a plurality of sensors integrated in the main controller, and a rechargeable battery connected to the main controller. At least one treatment fluid tank may be positioned on the robotic surface treatment device, and at least one treatment fluid tube may extend from a bottom surface of the treatment fluid tank to a bottom surface of the robotic surface treatment device. The sensors may be laser or acoustic sensors configured to create a boundary line for a treatment area. | 05-08-2014 |
Shuvamoy Saha, Bentonville, AR US
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20140195487 | REQUEST DE-DUPLICATION FOR ENTERPRISE SERVICE BUS - A method and system for providing temporary storage associated with a duplication request. The method includes authenticating a user accessing a system. A service request for performing service functions is received. Specified data associated with performing service functions is received from a third party vendor and description metadata is added to the specified data. The service functions are executed using the specified data. Results of the executed service functions are generated. An additional service request for performing additional service functions is received and intercepted. The description metadata is compared to previous service requests stored in a temporary storage system. | 07-10-2014 |
20150142719 | AUTOMATICALLY SELF-LEARNING BIDIRECTIONAL SYNCHRONIZATION OF A SOURCE SYSTEM AND A TARGET SYSTEM - A method and associated system for an automatically self-learning audit of a bidirectional synchronization means for synchronizing a source system and a target system. A processor identifies a mismatch between an element of production data of the source system and an analogous production-data element of the target system. If the mismatch is caused by an issue known to the synchronization means, the processor takes corrective action known to resolve the mismatch. Otherwise, the processor attempts to identify a resolution and, if successful, applies the resolution, teaches the resolution to the synchronization mechanism, records the solution, and resends data from the correct system to the incorrect system. If unable to identify a resolution, the processor implements a next-best solution that allows continued operation despite the unresolved mismatch. The processor then generates a report of the mismatch and continues searching for other mismatches in the loaded data models. | 05-21-2015 |
20150142737 | EFFICIENTLY FIRING MAPPING AND TRANSFORM RULES DURING BIDIRECTIONAL SYNCHRONIZATION - A method and associated system for efficiently firing mapping and transform rules during a bidirectional synchronization of two or more systems. A processor loads a set of mapping and transform synchronization rules and a set of cross-reference tables. When an event message received from a source system identifies a revision to an element of the source system's data, the processor parses the message to identify the revised source-system data. The processor uses the cross-references to identify synchronization rules that are associated with the revised data element. If any of the identified rules requires an additional source-system data element or an extrinsic data element located at an external source, the processor retrieves those further identified data elements. The processor then looks up the synchronization procedure of the identified rules, packages it into a synchronization message, and sends the message to the target system. | 05-21-2015 |
20150142740 | AUTOMATICALLY MANAGING MAPPING AND TRANSFORM RULES WHEN SYNCHRONIZING SYSTEMS - A method and associated system for managing rules that synchronize operations of a source system and a target system. A set of linked worksheets is generated as a function of the internal logic of the synchronization rules and of worksheets that represent data models of the source and target systems. These generated worksheets describe and relate data elements of the data models, extrinsic data that is stored externally to the source and target systems, and logical procedures performed by the synchronization rules. When the source data model, the target data model, or a logical procedure is revised, the linked worksheets are updated in response to the revision and these updates automatically propagate across the synchronization rules and across other components of the source system, the target system, and the synchronization mechanism. | 05-21-2015 |
Sourabh Kumar Saha, Newton, MA US
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20150197058 | WRINKLED SURFACES WITH TUNABLE HIERARCHY AND METHODS FOR THE PREPARATION THEREOF - This invention relates to the low-cost manufacture of a tunable physical topographic pattern and more particularly to the manufacture of micro and nano scale hierarchical periodic wrinkle patterns that are generated upon compression of supported thin films. Disclosed herein is (i) a composite material with tunable hierarchical wrinkle patterns, wherein the composite material comprises a stretched and pre-patterned base layer and a thin film that is conformally attached to the pre-patterned surface of the base layer, (ii) a method of fabricating the pre-patterned base via pattern replication, and (iii) a method of fabricating tunable hierarchical wrinkle patterns, wherein the pattern can be deterministically switched across the hierarchical and non-hierarchical states via strain control. | 07-16-2015 |
Sourabh Kumar Saha, Cambridge, MA US
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20140113019 | SYSTEM FOR PASSIVE ALIGNMENT OF SURFACES - Passive stamp alignment system. The system includes a stamp supported by a stamp holder resting on three balls affixed to a top platform. A bottom platform supports a substrate to be aligned with the stamp. Means are provided for moving either the top or the bottom platform and holding the other platform stationary so as to contact the substrate with the stamp whereby the stamp holder is lifted away from each of the balls in sequence resulting in alignment of the stamp and the substrate parallel to each other. | 04-24-2014 |
Sourav Saha, Tallahassee, FL US
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20110294229 | COLORIMETRIC AND FLUORIMETRIC FLUORIDE SENSING - The present invention generally relates to fluoride receptor reagent compounds comprising one or more N-aryl or heteroaryl substituted 1,4,5,8-naphthalenetetracarboxydiimide (NDI) units and an associated method for the detection of fluoride in a composition. π-electron orbitals present in the NDI unit of the reagents form a complex with fluoride anions. It is believed that the anion-π interaction results in a charge transfer process between the fluoride anion and the NDI unit, resulting in a number of measurable effects (e.g., colorimetric response). | 12-01-2011 |
Souvick Saha, Katy, TX US
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20130080059 | INTEGRATED DIP FROM 3D RESISTIVITY TOOL AND BOREHOLE IMAGING TOOL - A method for determining a dip of a geological structure in a subterranean formation, involves generating, using a 3D resistivity analyzer, a first intermediate result describing the dip of the geological structure based on 3D resistivity data collected from a borehole penetrating the subterranean formation. The method further involves generating, using a borehole image analyzer, a second intermediate result describing the dip of the geological structure based on a borehole image collected from the borehole. The method further involves generating, by a computer processor combining the first intermediate result and the second intermediate result based on a pre-determined criterion, an integrated result describing the dip of the geological structure. | 03-28-2013 |
Subhra Saha, Madison, AL US
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20100169478 | SYSTEMS, METHODS, AND COMPUTER PROGRAM PRODUCTS FOR ADAPTIVELY ADJUSTING A REGISTRATION INTERVAL OF AN ENDPOINT - Methods, systems, and computer program products for adaptively adjusting a registration interval of an endpoint are provided. In an embodiment of the subject matter disclosed herein, a method of adaptively adjusting a registration interval of an endpoint comprises determining a registration interval for an endpoint associated with a binding defined at a network address translation device. The method also comprises determining a stability of the binding based on a message received from the endpoint. Further, the method comprises adjusting the registration interval for the endpoint based on the determined stability of the binding. A message can be sent to the endpoint for indicating the adjusted registration interval. | 07-01-2010 |
Subhrajit Saha, Bronx, NY US
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20150118206 | STROMAL CELL THERAPY IN TREATMENT OF RADIATION INJURY - Methods are provided for treating, mitigating or protecting from radiation-induced injury using bone marrow stromal cells expanded in culture, adipose-tissue derived non-adherent stromal cells, or the culture supernatant thereof. | 04-30-2015 |
Sukumar Saha, Starkville, MS US
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20130227723 | Cotton PHYA1 RNAi Improves Fiber Quality, Root Elongation, Flowering, Maturity and Yield Potential in Gossypium hirsutum L. - Improvement of fiber quality of Upland cultivars ( | 08-29-2013 |
Sunipa Saha, Shoreview, MN US
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20100318151 | SYSTEMS AND METHODS FOR MANAGING NOISE IN IMPLANTABLE MEDICAL DEVICES - Embodiments of the invention are related to managing noise in sensed signals in implantable medical devices, amongst other things. In an embodiment the invention includes a method for processing electrical signals obtained from a patient including gathering a first set of electrical signals using an implantable medical device, filtering to provide a second set of electrical signals, the second set including frequencies above a threshold frequency, and estimating the amount of noise present in the first set of electrical signals based on the magnitude of the second set. In an embodiment, the invention includes a medical device configured to gather a first set of electrical signals, filter the first set to provide a second set of electrical signals including frequencies above a threshold frequency, and estimate the amount of noise present in the first set based on the magnitude of the second set. Other embodiments are also included herein. | 12-16-2010 |
20120035685 | USER INTERFACE SYSTEM FOR USE WITH MULTIPOLAR PACING LEADS - An interactive representation of electrostimulation electrodes or vectors can be provided, such as for configuring combinations of electrostimulation electrodes. In an example, electrodes or test parameters can be presented graphically or in a table. A user interface can be configured to receive user-input designating electrode combinations or vectors for test or for use in programming an implantable or ambulatory medical device. The interface can be used to indicate suggested electrode combinations or vectors in response to a first selection of an electrode. Tests can be performed on electrode combinations and vectors, and the results of the tests can be presented to a user using the interactive representation. In an example, test results can be analyzed by a processor and optionally used to program an implantable or ambulatory medical device. | 02-09-2012 |
20120130220 | GUIDEWIRE AND SIGNAL ANALYZER FOR PACING SITE OPTIMIZATION - Cardiac lead implantation systems, devices, and methods for lead implantation are disclosed. An illustrative cardiac lead implantation system comprises a mapping guidewire including one or more electrodes configured for sensing cardiac electrical activity, a signal analyzer including an analysis module configured for analyzing an electrocardiogram signal sensed by the mapping guidewire, and a user interface configured for monitoring one or more hemodynamic parameters within the body. The sensed electrical activity signal can be used by the analysis module to compute a timing interval associated with ventricular depolarization. | 05-24-2012 |
20120165897 | Rate Initialization and Overdrive Pacing for Capture Threshold Testing - Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold. | 06-28-2012 |
20130261471 | BASELINE DETERMINATION FOR PHRENIC NERVE STIMULATION DETECTION - Some method examples may include pacing a heart with cardiac paces, sensing a physiological signal for use in detecting pace-induced phrenic nerve stimulation, performing a baseline level determination process to identify a baseline level for the sensed physiological signal, and detecting pace-induced phrenic nerve stimulation using the sensed physiological signal and the calculated baseline level. Detecting pace-induced phrenic nerve stimulation may include sampling the sensed physiological signal during each of a plurality of cardiac cycles to provide sampled signals and calculating the baseline level for the physiological signal using the sampled signals. Sampling the sensed physiological signal may include sampling the signal during a time window defined using a pace time with each of the cardiac cycles to avoid cardiac components and phrenic nerve stimulation components in the sampled signal. | 10-03-2013 |
20130261476 | PHRENIC NERVE STIMULATION DETECTION - In an example, a system includes a cardiac pulse generator configured to generate cardiac paces to pace the heart, a sensor configured to sense a physiological signal for use in detecting pace-induced phrenic nerve stimulation where the pace-induced phrenic nerve stimulation is phrenic nerve stimulation induced by electrical cardiac pace signals, and a phrenic nerve stimulation detector configured to analyze the sensed physiological signal to detect PS beats where the PS beats are cardiac paces that induce phrenic nerve stimulation. The detector may be configured to correlate signal data for sensed beat signals to a PS template to detect PS beats, or may be configured to analyze morphological features of sensed beat signals to detect PS beats, or may be configured to detect PS beats using a combination that both correlates signal data for sensed beat signals to a PS template and analyzes morphological features of sensed beat signals. | 10-03-2013 |
20130261688 | DETERMINATION OF PHRENIC NERVE STIMULATION THRESHOLD - In an example of a method, the method includes testing for phrenic nerve stimulation (PS) threshold. If PS beats are detected at the pacing output level, analyzing the detected PS beats using criteria to determine if the pacing output level can be declared to be the PS threshold. If the pacing output level cannot be declared to be the PS threshold based on the analysis of the PS beat at the pacing output level, performing a PS beat confirmation procedure. The PS beat confirmation procedure may include delivering additional cardiac paces at the pacing output level to generate additional PS beats, and analyzing the detected PS beats using other criteria to determine if the pacing output level can be confirmed as the PS threshold. | 10-03-2013 |
20130310891 | AUTOMATIC PACING CONFIGURATION SWITCHER - A system or apparatus can provide electrostimulations via an electrode configuration that can be selected from multiple electrode configurations, the electrostimulations of the type for inducing a desired heart contraction, or a neurostimulation response. The system or apparatus can allow communicating with an external device to receive an input indicating a degree of patient discomfort with an electrostimulation delivered using a first electrode configuration, and can associate information about the degree of discomfort with information about the corresponding first electrode configuration for use by a controller circuit in determining a second electrode configuration for delivering a subsequent electrostimulation. | 11-21-2013 |
20130345537 | FAR-FIELD VS LOCAL ACTIVATION DISCRIMINATION ON MULTI-ELECTRODE EGMS USING VECTOR ANALYSIS IN MULTI-DIMENSIONAL SIGNAL SPACE - Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals are sampled from the electrode array and the signals are plotted in multi-dimensional space with each axis corresponding to a channel in the electrode array. An excursion direction of global activation in the multi-dimensional space is estimated and a change in vectors of the sampled signals over time is determined. Signals with vectors that change over time in the excursion direction are suppressed. | 12-26-2013 |
20130345577 | AUGMENTED SIGNAL VECTOR ANALYSIS TO SUPPRESS GLOBAL ACTIVATION DURING ELECTROPHYSIOLOGY MAPPING - Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals are sampled from the electrode array including signals from a channel of interest. An N-dimensional signal vector is then constructed using signals from N neighboring channels referenced to the channel of interest. A change in the N-dimensional signal vector over time is then determined and compared to a predetermined threshold to establish whether local activation has occurred on the channel of interest. | 12-26-2013 |
20130345583 | SUPPRESSION OF GLOBAL ACTIVITY DURING MULTI-CHANNEL ELECTROPHYSIOLOGY MAPPING USING A WHITENING FILTER - Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals from the electrode array are sampled, and the signals are plotted in multi-dimensional space with each axis corresponding to a channel in the electrode array. A covariance matrix of the plotted signals is decomposed to characterize the spread of a data cloud of the signals in the multi-dimensional space. The data cloud is then decorrelated, such as through whitening, to suppress excursions along correlated directions (global activation) and enhance excursions along each axis (local activation). | 12-26-2013 |
20140005742 | SYSTEM AND METHOD FOR SELECTION OF PACING VECTORS | 01-02-2014 |
20140018872 | ADAPTIVE PHRENIC NERVE STIMULATION DETECTION - An example of a system comprises a cardiac pulse generator configured to generate cardiac paces to pace the heart, a sensor configured to sense a physiological signal for use in detecting pace-induced phrenic nerve stimulation (PS), a storage, and a phrenic nerve stimulation detector. The storage is configured for use to store patient-specific PS features for PS beats with a desirably large signal-to-noise ratio. The phrenic nerve stimulation detector may be configured to detect PS features for the patient by analyzing a PS beat with a desirably large signal-to-noise ratio induced using a pacing pulse with a large energy output and store patient-specific PS features in the storage, and use the patient-specific PS features stored in the memory to detect PS beats when the heart is paced heart using cardiac pacing pulses with a smaller energy output. | 01-16-2014 |
20140107453 | REAL-TIME SIGNAL COMPARISON TO GUIDE ABLATION CATHETER TO THE TARGET LOCATION - A catheter system includes a plurality of mapping electrodes, an electrode movable relative to the plurality of mapping electrodes, and a guidance system coupled to the plurality of mapping electrodes and the ablation electrode. The guidance system is configured to receive signals associated with intrinsic cardiac activity sensed by the plurality of mapping electrodes and the movable electrode, and to correlate in real-time the intrinsic cardiac activity sensed by the movable electrode with the intrinsic cardiac activity sensed by the plurality of mapping electrodes based on the signals received by the plurality of mapping electrodes and movable electrode to determine a location of the movable electrode with respect to the plurality of mapping electrodes. | 04-17-2014 |
20140180051 | ROTOR IDENTIFICATION USING SEQUENTIAL PATTERN MATCHING - An anatomical mapping system includes a plurality of mapping electrodes each having an electrode location and configured to detect activation signals of intrinsic physiological activity within an anatomical structure. A mapping processor is associated with the plurality of mapping electrodes and is configured to record the detected activation signals and associate one of the plurality of mapping electrodes with each recorded activation signal. The mapping processor is further configured to analyze the recorded activation signals to identify at least one recurring pattern based on a relationship between a timing of the detected activation signals and the electrode locations of the mapping electrode associated with each detected activation signal. | 06-26-2014 |
20140180147 | ESTIMATING INTERSPLINE DISTANCES ON MAPPING CATHETERS - A catheter system includes a mapping catheter having a plurality of splines, each of the plurality of splines including a plurality of mapping electrodes. The system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive signals sensed by the plurality of mapping electrodes. The processor is further configured to estimate an interspline distance between adjacent splines in the plurality of splines based on the signals sensed by the mapping electrodes on the adjacent splines. | 06-26-2014 |
20140180151 | SUPPRESSION OF GLOBAL ACTIVATION SIGNALS DURING ANATOMICAL MAPPING - A method for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure, identifying at least one of the electrodes not in direct contact with the anatomical structure, and adjusting the activation signals sensed by each of the plurality of electrodes based on the activation signals sensed by the identified at least one of the electrodes not in direct contact with the anatomical structure. | 06-26-2014 |
20140180152 | REAL-TIME FEEDBACK FOR ELECTRODE CONTACT DURING MAPPING - A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on amplitudes of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization. | 06-26-2014 |
20140187989 | ESTIMATING RESTITUTION CURVES IN AN ANATOMICAL MAPPING SYSTEM - A method for mapping an anatomical structure includes sensing activation signals of physiological activity with a plurality of electrodes disposed in or near the anatomical structure, each activation signal having an associated cycle length, estimating an action potential duration and diastolic interval for each cycle length, generating a restitution curve based on the estimated action potential duration and diastolic interval from a preceding cycle length, iteratively optimizing each estimated action potential duration and corresponding diastolic interval to maximize a functional relationship between the estimated action potential duration and estimated diastolic interval from preceding cycle length, and generating an action potential duration restitution curve based on the optimized action potential durations and diastolic intervals. | 07-03-2014 |
20140187991 | ARTIFACT CANCELLATION TO SUPPRESS FAR-FIELD ACTIVATION DURING ELECTROPHYSIOLOGY MAPPING - A method for mapping a cardiac chamber includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the cardiac chamber, the activation signals including a near-field activation signal component and a far-field activation signal component, isolating R-wave events in the activation signals, generating a far-field activation template representative of the far-field activation signal component based on the R-wave events, and filtering the far-field activation template from the activation signals to identify the near-field activation signal components in the activation signals. | 07-03-2014 |
20140194943 | RATE INITIALIZATION AND OVERDRIVE PACING FOR CAPTURE THRESHOLD TESTING - Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold. | 07-10-2014 |
20140200457 | RECONSTRUCTION OF CARDIAC ACTIVATION INFORMATION BASED ON ELECTRICAL AND MECHANICAL MEANS - An anatomical mapping system includes a plurality of mapping electrodes, a plurality of mechanical sensors, and a mapping processor associated with the plurality of mapping electrodes and mechanical sensors. The mapping electrodes are configured to detect electrical activation signals of intrinsic physiological activity within an anatomical structure. The mechanical sensors are configured to detect mechanical activity associated with the intrinsic physiological activity. The mapping processor is configured to record the detected activation signals and associate one of the plurality of mapping electrodes and mechanical sensors with each recorded activation signal. The mapping processor is further configured to determine activation times of the intrinsic physiological activity based on a correlation of corresponding electrical activation signals and mechanical activity. | 07-17-2014 |
20140277244 | AMBULATORY PHRENIC NERVE STIMULATION DETECTION - An example of a system includes an implantable medical device (IMD) for implantation in a patient, where the IMD includes a cardiac pace generator, phrenic nerve stimulation (PS) sensor, a memory, and a controller, and where the controller is operably connected to the cardiac pace generator to generate cardiac paces. The controller is configured to provide a trigger for conducting a PS detection procedure and perform the PS detection procedure in response to the trigger. In performing the PS detection procedure the controller is configured to receive a signal from the sensor, detect PS using the signal from the sensor, and record the PS detection in storage within the IMD. | 09-18-2014 |
20140277280 | PHRENIC NERVE STIMULATION DETECTION WITH POSTURE SENSING - A method and a system of phrenic nerve stimulation detection in conjunction with posture sensing is disclosed. In an embodiment, the method may include receiving a trigger for conducting a pace-induced phrenic nerve stimulation (PS) search using the IMD within the patient. On receiving the trigger, the IMD may be used for conducting the PS search. A procedure of conducting the PS search may include measuring a posture of the patient using an implantable posture sensor, searching for PS while the patient is in the measured posture and obtaining a PS result from the PS search for the measured posture. The method may include recording both the PS result and the measured posture in a memory of the IMD. | 09-18-2014 |
20140316294 | METHOD AND APPARATUS FOR SUPPRESSING FAR-FIELD SENSING DURING ATRIAL MAPPING - A method and system for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure. Substantially similar activation signals are binned according to a self-correlation algorithm which identifies patterns among the sensed activation signals. A template is generated for each bin and compared to a characteristic template to identify at least one bin which corresponds to a far-field activation signal. | 10-23-2014 |
20140330150 | PERSISTENT DISPLAY OF NEAREST BEAT CHARACTERISTICS DURING REAL-TIME OR PLAY-BACK ELECTROPHYSIOLOGY DATA VISUALIZATION - A system and method for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure. A most recent intrinsic event at a selected time is determined based on the sensed activation signals and a persistent display of relevant characteristics is generated based on the sensed activation signals of the most recent intrinsic event. The persistent display is updated upon detection of a subsequent intrinsic event. | 11-06-2014 |
20140336518 | SYSTEM FOR IDENTIFYING ROTOR PROPAGATION VECTORS - A method and system for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure. The activation signals are used to determine a dominant frequency for each electrode from which a wavefront vector for each electrode is determined based on a difference between the dominant frequency at a first electrode location and the dominant frequency at neighboring electrodes. An anatomical map is generated based on the determined wavefront vectors. | 11-13-2014 |
20140343388 | Representation and identification of activity patterns during electro-physiology mapping using vector fields - A method and system for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure, each of the plurality of mapping electrodes having an electrode location. A vector field map which represents a direction of propagation of the activation signals at each electrode location is generated to identify a signature pattern and a location in the vector field map according to at least one vector field template. A target location of the identified signature pattern is identified according to a corresponding electrode location. | 11-20-2014 |
20140343442 | ENHANCED ACTIVATION ONSET TIME OPTIMIZATION BY SIMILARITY BASED PATTERN MATCHING - An anatomical mapping system and method includes mapping electrodes configured to detect activation signals of cardiac activity. A processing system is configured to record the detected activation signals and generate a vector field for each sensed activation signal during each instance of the physiological activity. The processing system determines an onset time and alternative onset time candidates, identifies an initial vector field template based on a degree of similarity between the initial vector field and a vector field template from a bank of templates, then determines an optimized onset time for each activation signal based on a degree similarity between the onset time candidates and initial vector field template. | 11-20-2014 |
20150065836 | ESTIMATING THE PREVALENCE OF ACTIVATION PATTERNS IN DATA SEGMENTS DURING ELECTROPHYSIOLOGY MAPPING - A system and method for mapping an anatomical structure includes sensing activation signals of physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure. Patterns among the sensed activation signals are identified based on a similarity measure generated between each unique pair of identified patterns which are classified into groups based on a correlation between the corresponding pairs of similarity measures. A characteristic representation is determined for each group of similarity measures and displayed as a summary plot of the characteristic representations. | 03-05-2015 |
20150066102 | UNWANTED STIMULATION DETECTION DURING CARDIAC PACING - The disclosure relates to systems and methods for cardiac rhythm management. In some cases, a system may include a pulse generator for generating pacing pulses for stimulating a heart of a patient; a memory; and a sensor configured to sense a response to a unwanted stimulation and to produce a corresponding sensor signal. A processing circuit may receive the sensor signal for a time after one or more pacing pulses, and may derive a time-frequency representation of the sensor signal based on the received sensor signal. The processing circuit may use the time-frequency representation of the sensor signal to help identify unwanted stimulation. Once unwanted stimulation is detected, the processing circuit may change the pacing pulses to help reduce or eliminate the unwanted stimulation. | 03-05-2015 |
20150066103 | UNWANTED STIMULATION DETECTION DURING CARDIAC PACING - The disclosure relates to systems and methods for cardiac rhythm management. In some cases, a system may include a pulse generator for generating pacing pulses for stimulating a heart of a patient; a memory; and a sensor configured to sense a response to a unwanted stimulation and to produce a corresponding sensor signal. A processing circuit may receive the sensor signal for a time after one or more pacing pulses, and may derive a time-frequency representation of the sensor signal based on the received sensor signal. The processing circuit may use the time-frequency representation of the sensor signal to help identify unwanted stimulation. Once unwanted stimulation is detected, the processing circuit may change the pacing pulses to help reduce or eliminate the unwanted stimulation. | 03-05-2015 |
20150100103 | CARDIAC PACING WITH ANODAL STIMULATION DETECTION - Methods and device for determining a pacing vector for delivering an electrostimulation therapy are described. An implantable medical device may be configured to determine an anode capture threshold and a cathode capture threshold for a first anode and cathode pair of electrodes, switch a polarity of the first anode and cathode pair of electrodes, and determine an anode capture threshold and a cathode capture threshold for the first anode and cathode pair of electrodes having the switched polarity. The implantable medical device may be further configured to compare a cathodal capture threshold for the anode and cathode pair having the switched polarity to the anodal capture threshold of the first anode and cathode pair of electrodes and select either an anode or a cathode for delivering an electrostimulation therapy based at least in part on the comparison. Other methods and systems are also contemplated and described. | 04-09-2015 |
20150119672 | MEDICAL DEVICE FOR HIGH RESOLUTION MAPPING USING LOCALIZED MATCHING - Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The catheter shaft may be coupled to a processor. The processor may be capable of collecting a first set of signals from a first location, collecting a second set of signals from a second location, characterizing the first set of signals over a first time period, characterizing the second set of signals over a second time period, comparing the first set of signals to the second set of signals and matching a first signal from the first set of signals with a second signal from the second set of signals. | 04-30-2015 |
20150126840 | CARDIAC MAPPING USING LATENCY INTERPOLATION - Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The plurality of electrodes may include a first pair of electrodes, a second pair of electrodes, a third pair of electrodes and a fourth pair of electrodes. The mapping medical device may further include a processor, wherein the processor may be configured to determine a first latency between the first pair of electrodes, determine a second latency between the second pair of electrodes, determine a third latency between the third pair of electrodes, determine a fourth latency between the fourth pair of electrodes, and determine a target signal by interpolating the first latency, the second latency, the third latency and the fourth latency. | 05-07-2015 |
20150134025 | SYSTEM AND METHOD FOR SELECTION OF PACING VECTORS - Various techniques are disclosed for quickly and efficiently determining cardiac pacing vectors that minimize phrenic nerve stimulation. | 05-14-2015 |
Susmita G. Saha, Longmont, CO US
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20090074173 | LOCAL ROUTING MANAGEMENT IN A TELECOMMUNICATIONS NETWORK - An embodiment of a method includes generating one or more route plans, each route plan being associated with a service plan, and provisioning the one or more route plans on a core routing engine accessible by a softswitch for routing calls according to the one or more route plans. The one or more route plans may include an on-net route plan and an off-net route plan. An embodiment of a system includes a local route manager (LRM) configured to generate one or more route plans associated with one or more respective service levels that customers can subscribe to. The system may further include an inventory of trunk groups containing a plurality of trunk group identifiers (IDs), wherein trunk group IDs are marked as either on-net or off-net. | 03-19-2009 |
20090080630 | LOCAL ROUTING MANAGEMENT IN A TELECOMMUNICATIONS NETWORK - An embodiment of a method includes determining a customer service plan identifier from information associated with a received call, determining a route plan associated with the identified customer service plan, and routing the call on a trunk group identified in the determined route plan. The method may further include determining a jurisdiction of the call based on a dialed number identified in the call, determining a local routing number (LRN) associated with the call, and using a portion of the LRN to determine the trunk group. An embodiment of a system includes a switch operable to select a route for routing a call received on an ingress trunk associated with a customer that subscribes to a service plan, wherein the switch is further operable to select the route based on the service plan subscribed to by the customer associated with the ingress trunk. | 03-26-2009 |
20110085541 | LOCAL ROUTING MANAGEMENT IN A TELECOMMUNICATIONS NETWORK - An embodiment of a method includes determining a customer service plan identifier from information associated with a received call, determining a route plan associated with the identified customer service plan, and routing the call on a trunk group identified in the determined route plan. The method may further include determining a jurisdiction of the call based on a dialed number identified in the call, determining a local routing number (LRN) associated with the call, and using a portion of the LRN to determine the trunk group. An embodiment of a system includes a switch operable to select a route for routing a call received on an ingress trunk associated with a customer that subscribes to a service plan, wherein the switch is further operable to select the route based on the service plan subscribed to by the customer associated with the ingress trunk. | 04-14-2011 |
Susmita G. Saha US
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20100254526 | LOCAL ROUTING MANAGEMENT IN A TELECOMMUNICATIONS NETWORK - An embodiment of a method includes generating one or more route plans, each route plan being associated with a service plan, and provisioning the one or more route plans on a core routing engine accessible by a softswitch for routing calls according to the one or more route plans. The one or more route plans may include an on-net route plan and an off-net route plan. An embodiment of a system includes a local route manager (LRM) configured to generate one or more route plans associated with one or more respective service levels that customers can subscribe to. The system may further include an inventory of trunk groups containing a plurality of trunk group identifiers (IDs), wherein trunk group IDs are marked as either on-net or off-net. | 10-07-2010 |
Syamantak Saha, New York, NY US
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20120023123 | Zapaat Context Web Search - Current Internet search methods use Keywords as input to provide information back to users. However, this method provides information which might not be the web pages which are being searched. Due to the conceptual singular input of Keyword, the efficiency of the information provided is compromised. | 01-26-2012 |
20120089428 | PEN Analysis for Quantified Perspectives in Decision Making - Organisations make decisions based on its Perspectives. These Perspectives exist within an environment with ever changing variables. It is of utmost importance that those Perspectives are relevant and valid in the current environment. Perspectives which are outdated or invalid, causes decisions and business activities which are inefficient for the Organisation. They will lead to business processes which are not integrated with the main thrust of the Organisation's workings. Hence, Perspectives need to be validated constantly, to ensure that all business processes are well integrated and exist in accordance to the objectives of the Organisation. However, there is no Analysis Technique which exists for Organisations to validate their Perspectives for Decision Making. In this paper, a Statistics based Analysis technique called PEN Analysis, is introduced. Using this technique, Organisations can validate their Perspectives for Decision Making and cumulative business process integration. | 04-12-2012 |
Tarun K. Saha, Fishkill, NY US
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20140279830 | DATA INTEGRATION USING AUTOMATED DATA PROCESSING BASED ON TARGET METADATA - Approaches for data integration between multiple IT sources using automated data processing based on target metadata are provided. Specifically, an integration component is configured to load a mapped data set into a table with delta processing based on a configuration object containing, e.g., the source data location, target table name, and source to target mapping. The integration component uses the target metadata to validate data, identify changes, generate the necessary database programming language (e.g., structured query language (SQL)), and run the database programming language with data binding to perform the actual data updates. The integration component leverages the data target metadata to automate the processing of source data, thus providing a way to validate the data, and identify delta changes at the field level between the source and target. This significantly reduces the overall development effort, while providing consistency in record handling and error reporting. | 09-18-2014 |
20140310789 | USER ACCESS CONTROL TO A SECURED APPLICATION - Embodiments described herein provide approaches for user access control to a secured application. Specifically, a custom authentication tool is configured to intercept a request from a user for access to a secured application and override one or more default requirements (e.g., application pre-registration, for accessing the application). That is, when credentials of the user are received at the authentication tool, they are verified against data within a user directory to generate a user profile, which is then provided to the secured application to satisfy the requirements for granting access to the user. As such, the secured application's requirements are met, yet users do not have to manually pre-register to obtain access because the registration is performed in the background by the authentication tool. | 10-16-2014 |