Saal
Christoph Saal, Otzberg DE
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20090176820 | POLYMORPHIC FORMS AND PROCESS - The invention relates to a process for the manufacture of enantiomerically enriched or pure compounds of formula I | 07-09-2009 |
20110009437 | CARBOXAMIDE-HETEROARYL DERIVATIVES FOR THE TREATMENT OF DIABETES - Novel heterocyclic compounds of the formula I | 01-13-2011 |
20110009455 | 5-Oxo-2,3,4,5-tetrahydro-benzo[b]oxepine-4-carboxylic acid amides and 2,3-Dihydro-benzo[b]oxepine-4-carboxylic acid amides for treatment and prevention of Diabetes Typ 1 and 2 - The present invention relates to novel compounds of general formula (I) | 01-13-2011 |
20110196041 | Novel crystal form of calcium 3-acetylaminopropane-1-sulfonate - The present invention relates to a novel crystal form of calcium 3-acetylaminopropane-1-sulfonate, to a process for the preparation thereof, and to the use thereof in medicaments. | 08-11-2011 |
20110257180 | Novel Polymorphic Forms of 6-(1-methyl-1H-pyrazol-4-yl)-2--2H-pyridazin-3-one Dihydrogenphosphate and Processes of Manufacturing thereof - The present invention relates to 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-2-yl]-benzyl}-2H-pyridazin-3-one dihydrogenphosphate, its solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer. | 10-20-2011 |
20110269767 | Novel Polymorphic Forms of 3-(1--6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile Hydrochloride Salt and Processes of Manufacturing Thereof - The present invention relates to 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile hydrochloride solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer. | 11-03-2011 |
20120065142 | NOVEL SOLID MATERIALS OF AND METHODS FOR OBTAINING THEM - The instant invention relates to novel solid materials of {[(2S,5R,8S,11S)-5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid}, methods for producing them, and the use of said solid materials in pharmaceuticals. | 03-15-2012 |
20140088022 | Novel Solid Materials of and Methods for Obtaining Them - The instant invention relates to novel solid materials of {[(2S,5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid}, methods for producing them, and the use of said solid materials in pharmaceuticals. | 03-27-2014 |
20140200221 | NOVEL POLYMORPHIC FORMS OF 3-(1--6-OXO-1,6-DIHYDRO-PYRIDAZIN-3-YL)-BENZONITRILE HYDROCHLORIDE SALT AND PROCESSES OF MANUFACTURING THEREOF - The present invention relates to 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile hydrochloride solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer. | 07-17-2014 |
20140336274 | PROCESS FOR PRODUCING INORGANIC PARTICULATE MATERIAL - The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent. | 11-13-2014 |
Helmut Saal, Reiferscheid DE
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20130027879 | METHOD FOR REGULATING A COOLING SYSTEM - The invention relates to a method for regulating a cooling system for cooling electrical built-in devices housed in control panels or racks by means of cooling units assigned thereto, through which a liquid cooling medium, cooled down from a return temperature to a flow temperature by means of a cooling apparatus of the cooling system flows, wherein a cooling power for cooling the built-in devices can be regulated by a primary reference variable according to specification. Energy-efficient cooling is achieved in that the flow temperature is variably adjusted according to a cooling power demand in the region of the built-in devices, wherein the primary reference variable is formed from the cooling power demand in the region of the built-in devices. | 01-31-2013 |
Helmut Saal, Soerth DE
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20120087087 | Method And Device For Controlling An Air Conditioning System For Data Processing Facilities - The invention relates to a method for controlling an air conditioning system for a data processing facility that comprises at least one row of server switch cabinets, wherein the row of server switch cabinets bounds a cold aisle that is sealed off from a hot aisle facing away from the cold aisle side, wherein hot air is drawn in, cooled, and blown into the cold aisle by at least one air conditioner, and wherein cold air is drawn out of the cold aisle and fed into the hot aisle or into the surrounding space by at least one of the server switch cabinets. The invention further relates to a corresponding device for performing the method. According to the invention, the control of the air supply rate of the air conditioner is performed by means of a pressure controller, wherein a measured pressure difference between a pressure sensor in the cold aisle or in the hot aisle and a pressure sensor in the surrounding space outside the cold aisle or the hot aisle is used as an input variable of the pressure controller. The device comprises a control unit for performing the method. Using the method and the device, optimal and at the same time energy-saving cooling of such data processing facilities can be provided. In addition, the operational reliability is increased, because failures or defects in the air supply can be detected directly. | 04-12-2012 |
James E. Saal, Chicago, IL US
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20150086413 | MAGNESIUM ALLOYS HAVING LONG-PERIOD STACKING ORDER PHASES - Magnesium alloys comprising a long period stacking order (LPSO) phase having an 14H-i or an 18R-i structure are provided. The alloys comprise magnesium as a majority element, a first alloying element that is larger than magnesium and a second alloying element that is smaller than magnesium. The first alloying elements include non-rare earth elements. | 03-26-2015 |
Klaus Saal, Munchen DE
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20080319888 | Allocation of residual value risk - Residual value risk may be allocated for a leased vehicle between a dealer organization and a manufacturer group, where the manufacturing group may include both a financing institution and a sales organization. In one embodiment, residual value risk may be allocated by first calculating a difference between a residual value for the leased vehicle and the vehicle's actual value. This difference may then be allocated between the manufacturer group and the dealer organization according to some predetermined ratio which represents a corresponding financial obligation or benefit, depending on if the difference is positive or negative. | 12-25-2008 |
Kristjan Saal, Ulenurme Parish EE
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20120019760 | METHOD OF PREPARATION OF SURFACE COATING OF VARIABLE TRANSMITTANCE AND ELECTRO-OPTICAL APPLIANCE INCLUDING THE SAME - Method of preparation of surface coating of variable transmittance and an electro-optical layered appliance including the same comprises dispersing of liquid crystal microdroplets in hydrolyzable and polymerizable precursors and applying obtained mixture on a surface by spraying. Applying the material to the surface by spraying is intrinsically related to the synthesis processes because the properties of the surrounding environment (i.e. content of water and acidity, UV radiation) and the chemical reactions that take place during spraying have considerable influence on the properties (i.e. driving voltage, thickness of obtained layer). Obtained layered appliance comprises of a matrix material with dispersed microdroplets of liquid crystal obtained by the described method, electrically conductive transparent electrodes with contacts, a dielectric material, substrate and covering layers. | 01-26-2012 |
Peter L. Saal, Boulder, CO US
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20130201189 | SYSTEMS FOR PARAMETRIC MODELING OF THREE DIMENSIONAL OBJECTS - A system for parametric modeling of a three-dimensional object has a processor running a software program operable to configure the object by defining a zone comprising a root of a tree hierarchy, the zone having a three-dimensional region defining an outer dimension of the object to be modeled; a part comprising a child of the zone, the part also having a component object to be modeled, wherein the component object is an element of the object; and a variable comprising a child of the part, wherein variable has data defining characteristics of the zone or part. A user interface can display a representation of the three-dimensional object. | 08-08-2013 |
Stuart D. Saal, New York, NY US
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20140171391 | METHOD FOR TREATING SEPSIS IN PATIENTS WITH ALBUMIN, CHOLESTEROL AND HDL LEVELS ABOVE MINIMUM THRESHOLDS - The invention relates to a method for treating sepsis in subjects who exhibit serum albumin levels, and one of total cholesterol or HDL levels, above minimum threshold values. The method involves intravenous administration of an emulsion, which contains a phospholipid, a neutral lipid, and a cholate salt. | 06-19-2014 |