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| 20120123315 | INTRAOCULAR SHUNTS - The present invention generally relates to different types of intraocular shunts. | 05-17-2012 |
| 20120123316 | INTRAOCULAR SHUNTS FOR PLACEMENT IN THE INTRA-TENON'S SPACE - The present invention generally relates to intraocular shunts, and in particular, to intraocular shunts configured to form a drainage pathway between the anterior chamber and the intra-Tenon's space. | 05-17-2012 |
| 20120165720 | INTRAOCULAR SHUNTS - The present invention generally relates to different types of intraocular shunts. | 06-28-2012 |
| 20120165722 | DEVICES AND METHODS FOR IMPLANTING A SHUNT IN THE SUPRACHOROIDAL SPACE - The invention generally relates to devices and methods for implanting a shunt in the suprachoroidal space of an eye. In certain aspects, devices of the invention include a housing, a deployment mechanism at least partially disposed within the housing, and a flexible hollow shaft coupled to the deployment mechanism, in which the shaft holds an intraocular shunt, and is configured to self-guide the shunt along a scleral spur of an eye as the shunt is deployed from the shaft. Such a device may be inserted into an eye and used to deploy a shunt within the eye such that a proximal portion of the shunt receives fluid from an anterior chamber of an eye and a distal portion of the shunt directs the fluid to the suprachoroidal space. | 06-28-2012 |
| 20120165723 | METHODS FOR IMPLANTING A SOFT GEL SHUNT IN THE SUPRACHOROIDAL SPACE - The invention generally relates to methods for implanting a soft gel shunt in the suprachoroidal space. In certain embodiments, methods of the invention involve inserting into the eye a hollow shaft configured to hold a soft gel intraocular shunt, deploying the soft gel shunt from the hollow shaft such that the shunt forms a passage from the anterior chamber of the eye to the suprachoroidal space of the eye, and withdrawing the hollow shaft from the eye. | 06-28-2012 |
| 20120197175 | METHODS, SYSTEMS AND APPARATUS FOR RELIEVING PRESSURE IN AN ORGAN - The invention generally relates to shunts in which at least a portion of the body includes a drug. | 08-02-2012 |
| 20140236066 | ADJUSTABLE INTRAOCULAR FLOW REGULATION - Methods and devices for adjusting or configuring the flow rate of an intraocular shunt are provided whereby hypotony can be avoided by increasing the flow rate through the device. In some embodiments, the device is a shunt that can have a first flow that can be modified to a second flow by modifying the shunt, such as by cutting the shunt. Additionally, one or more dissolvable portions can be present to provide an initial flow restriction and subsequent increase in flow over time. | 08-21-2014 |
| 20140236067 | ADJUSTABLE GLAUCOMA IMPLANT - Methods and devices for adjusting or configuring the flow rate of an intraocular shunt are provided whereby hypotony can be avoided by increasing the flow rate through the device. In some embodiments, the device is a shunt that can have a first flow that can be modified to a second flow by modifying the shunt, such as by cutting the shunt. Additionally, one or more dissolvable portions can be present to provide an initial flow restriction and subsequent increase in flow over time. | 08-21-2014 |
| 20150133946 | INTRAOCULAR SHUNT INSERTER - An inserter for treating glaucoma can comprise a housing, a needle, a plunger, a slider component, and a drive component. The drive component is disposed within a cavity of the housing and rotatable within the cavity to result in movement along a longitudinal axis of the inserter to the needle and the plunger upon rotation of the drive component. The slider component is coupled to the housing and slidable along an elongate groove of the drive component such that movement of the slider component along the axis rotates the drive component within the housing. | 05-14-2015 |
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| 20090139854 | CONTROL OF ARBITRARY SCAN PATH OF A ROTATING MAGNETRON - A control system and method for controlling two motors determining the azimuthal and circumferential position of a magnetron rotating about the central axis of the sputter chamber in back of its target sputtering and capable of a nearly arbitrary scan path, e.g., with a planetary gear mechanism. A system controller periodically sends commands to the motion controller which closely controls the motors. Each command includes a command ticket, which may be one of several values. The motion controller accepts only commands having a command ticket of a different value from the immediately preceding command. One command selects a scan profile stored in the motion controller, which calculates motor signals from the selected profile. Another command instructs a dynamic homing command which interrogates sensors of the position of two rotating arms to determine if the arms in the expected positions. If not, the arms are rehomed. | 06-04-2009 |
| 20110209995 | Physical Vapor Deposition With A Variable Capacitive Tuner and Feedback Circuit - Apparatus and methods for performing plasma processing on a wafer supported on a pedestal are provided. The apparatus can include a pedestal on which the wafer can be supported, a variable capacitor having a variable capacitance, a motor attached to the variable capacitor which varies the capacitance of the variable capacitor, a motor controller connected to the motor that causes the motor to rotate, and an output from the variable capacitor connected to the pedestal. A desired state of the variable capacitor is associated with a process recipe in a process controller. When the process recipe is executed the variable capacitor is placed in the desired state. | 09-01-2011 |
| 20120103800 | Homing of arbitrary scan path of a rotating magnetron - A control system and method for controlling two motors determining the azimuthal and circumferential position of a magnetron rotating about the central axis of the sputter chamber in back of its target sputtering and capable of a nearly arbitrary scan path, e.g., with a planetary gear mechanism. A system controller periodically sends commands to the motion controller which closely controls the motors. Each command includes a command ticket, which may be one of several values. The motion controller accepts only commands having a command ticket of a different value from the immediately preceding command. One command selects a scan profile stored in the motion controller, which calculates motor signals from the selected profile. Another command instructs a dynamic homing command which interrogates sensors of the position of two rotating arms to determine if the arms in the expected positions. If not, the arms are rehomed. | 05-03-2012 |
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| 20090070844 | VIDEO OVER IP DISTRIBUTION SYSTEM AND METHOD - Enables video over IP distribution system and method that multicasts or broadcasts IP messages over a local layer 2 network (generally for example in a known local network, e.g., a network within an Internet service provider or video provider) to eliminate intermediate replication servers. The system thus utilizes a flat architecture that distributes the same number of video streams as pyramid architectures, but utilizes less hardware, e.g., less replication servers and less network switches. Systems may be configured to transmit multiple versions of the same broadcast, for example at different sizes, resolutions or aspect ratios or at different bit rates or any combination thereof. Groupings of the system allow for customized broadcast of the same video. With respect to quality of service, various clock synchronization, forward error correction (FEC), automatic repeat request (ARQ) methods and systems may be utilized to provide higher quality of service for any embodiment of the invention. | 03-12-2009 |
| 20090196282 | METHODS AND APPARATUS FOR PROVIDING QUALITY-OF-SERVICE GUARANTEES IN COMPUTER NETWORKS - An arbitration mechanism provides quality of service guarantees for time-sensitive signals sharing a local area computer network with non-time-sensitive traffic. Device adapters are placed at all access points to an Ethernet network. The device adapters limit admission rates and control the timing of all packets entering the network. By doing so, collisions are eliminated for timesensitive traffic, thereby guaranteeing timely delivery. A common time reference is established for the device adapters. The time reference includes a frame with a plurality of phases. Each of the phases is assigned to a device adapter. Each device adapter is allowed to transmit packets of data onto the network only during the phase assigned thereto. The length of the phases may be modified in accordance with the number of packets to be transmitted by a particular device adapter. A master device adapter may be appointed to synchronize each of the device adapters. | 08-06-2009 |
| 20130073679 | METHODS AND APPARATUS FOR PROVIDING QUALITY OF SERVICE GUARANTEES IN COMPUTER NETWORKS - An arbitration mechanism provides quality of service guarantees for time-sensitive signals sharing a local area computer network with non-time-sensitive traffic. Device adapters are placed at all access points to an Ethernet network. The device adapters limit admission rates and control the timing of all packets entering the network. By doing so, collisions are eliminated for timesensitive traffic, thereby guaranteeing timely delivery. A common time reference is established for the device adapters. The time reference includes a frame with a plurality of phases. Each of the phases is assigned to a device adapter. Each device adapter is allowed to transmit packets of data onto the network only during the phase assigned thereto. The length of the phases may be modified in accordance with the number of packets to be transmitted by a particular device adapter. A master device adapter may be appointed to synchronize each of the device adapters. | 03-21-2013 |
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| 20080316471 | DETERMINING AZIMUTH ANGLE OF INCIDENT BEAM TO WAFER - A method, system and computer program product for determining an Azimuth angle of an incident beam to a wafer are disclosed. A method comprises: using the incident beam to make a first set of measurements of calibration targets of a first set of grating angles that are different than one another; analyzing the first set of measurements to determine an reference grating angle which corresponds to a grating line to which the incident beam has a practically zero Azimuth angle; and determining the Azimuth angle of the incident beam to the wafer using the determined reference grating angle. | 12-25-2008 |
| 20090009763 | FLIPPING STAGE ARRANGEMENT FOR REDUCED WAFER CONTAMINATION CROSS SECTION AND IMPROVED MEASUREMENT ACCURACY AND THROUGHPUT - A sample stage for performing measurements using an optical metrology system includes at least one sample section for retention of a sample, and components for controlling orientation of the sample section with relation to the optical metrology system. A method and a computer program product are provided. | 01-08-2009 |
| 20090027660 | OPTICAL SPOT GEOMETRIC PARAMETER DETERMINATION USING CALIBRATION TARGETS - A method, system and computer program product for determining a geometric parameter of an optical spot of a light beam are disclosed. A method comprises: providing a calibration target, the calibration target including a systematic variation in a parameter; measuring the calibration target with respect to the systematic variation using the light beam to obtain a plurality of measurements; and analyzing the measurements and the systematic variation to determine the geometric parameter of the optical spot. | 01-29-2009 |
| 20090185183 | MONITORING STAGE ALIGNMENT AND RELATED STAGE AND CALIBRATION TARGET - Methods, apparatuses and systems for monitoring a stage alignment in a processing system are disclosed. A method for monitoring a stage alignment in a processing system may include providing a calibration target on a surface of the stage; measuring an angle of incident of a light beam to the calibration target; and monitoring the stage alignment based on the determined angle of incidence. | 07-23-2009 |
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| 20080200415 | Plant Activation of Insect Toxin - Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds. | 08-21-2008 |
| 20090075287 | METHODS FOR IDENTIFYING NOVEL PESTICIDAL GENE HOMOLOGUES - Methods and compositions for identifying novel pesticidal gene homologues are provided. Specifically, the methods of the invention comprise systematically designing oligonucleotide primers that are specific for a pesticidal gene of interest and performing successive rounds of PCR amplification of nucleic acid material from a microorganism, particularly a | 03-19-2009 |
| 20090130672 | METHODS FOR IDENTIFYING NOVEL PESTICIDAL GENE HOMOLOGUES - Methods and compositions for identifying novel pesticidal gene homologues are provided. Specifically, the methods of the invention comprise systematically designing oligonucleotide primers that are specific for a pesticidal gene of interest and performing successive rounds of PCR amplification of nucleic acid material from a microorganism, particularly a | 05-21-2009 |
| 20090203042 | NOVEL BT TOXIN RECEPTORS FROM LEPIDOPTERAN INSECTS AND METHODS OF USE - The invention relates to Bt toxin resistance management. The invention particularly relates to the isolation and characterization of nucleic acid and polypeptides for a novel Bt toxin receptor. The nucleic acid and polypeptides are useful in identifying and designing novel Bt toxin receptor ligands including novel insecticidal toxins. | 08-13-2009 |
| 20090291896 | GENES ENCODING NOVEL PROTEINS WITH PESTICIDAL ACTIVITY AGAINST COLEOPTERANS - The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of | 11-26-2009 |
| 20090317891 | PLANT ACTIVATION OF INSECT TOXIN - Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds. | 12-24-2009 |
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| 20090257908 | Ultra Supercritical Boiler Header Alloy and Method of Preparation - A high temperature, high strength Ni—Co—Cr alloy possessing essentially fissure-free weldability for long-life service at 538° C. to 816° C. contains in % by weight about: 23.5 to 25.5% Cr, 15-22% Co, 1.1 to 2.0% Al, 1.0 to 1.8 % Ti, 0.95 to 2.2% Nb, less than 1.0% Mo, less than 1.0% Mn, less than 0.3% Si, less than 3% Fe, less than 0.3% Ta, less than 0.3% W, 0.005 to 0.08% C, 0.01 to 0.3% Zr, 0.0008 to 0.006% B, up to 0.05% rare earth metals, 0.005% to 0.025% Mg plus optional Ca and the balance Ni including trace additions and impurities. The strength and stability is assured at 760° C. when the Al/Ti ratio is constrained to between 0.95 and 1.25. Further, the sum of Al+Ti is constrained to between 2.25 and 3.0. The upper limits for Nb and Si are defined by the relationship: (% Nb+0.95)+3.32(% Si)<3.16. | 10-15-2009 |
| 20090321405 | Ni-Co-Cr High Strength and Corrosion Resistant Welding Product and Method of Preparation - A nickel (Ni), chromium (Cr), cobalt (Co), iron (Fe), molybdenum (Mo), manganese (Mn), aluminum (Al), titanium (Ti), niobium (Nb), silicon (Si) welding alloy, articles made therefrom for use in producing weldments and methods for producing these weldments. The welding alloy contains in % by weight about: 23.5 to 25.5% Cr, 15 to 22% Co, up to 3% Fe, up to 1% Mo, up to 1% Mn, 1.1 to 2.0% Al, 0.8 to 1.8% Ti, 0.8 to 2.2% Nb, 0.05 to 0.28% Si, up to 0.3% Ta, up to 0.3% W, 0.005 to 0.08% C, 0.001 to 0.3% Zr, 0.0008 to 0.006% B, up to 0.05% rare earth metals, up to 0.025% Mg plus optional Ca and the balance Ni including trace additions and impurities. The welding alloy offers a combination of high temperature strength, ductility, stability, toughness and essentially defect-free weldability and weldments as to render the alloy range uniquely suitable for joining boiler tubing to the header pipe in supercritical, ultra-supercritical and advanced ultra-supercritical boiler applications where essentially defect-free joining is critical. | 12-31-2009 |
| 20130206274 | PROCESS FOR PRODUCING LARGE DIAMETER, HIGH STRENGTH, CORROSION-RESISTANT WELDED PIPE AND PIPE MADE THEREBY - A method of roll-forming sheet or plate into a round hollow, welding the round hollow with a welding alloy that matches the alloy of the round hollow to form a welded pipe, annealing the welded pipe at a minimum of 1950° F. to provide a carbide-free microstructure, ultrasonic inspecting to assure sound welds, and cold-working the annealed and inspected pipe via drawing or pilgering to the desired tensile strength. The compositional range alloys suitable for use in the method of the present invention in weight % is: 25.0-65.0% Ni, 15.0-30.0% Cr, 0-18.0% Mo, 2.5-48.0% Fe, 0-5.0% Cu, 0-5.0% Mn, 0-5.0% Nb, 0-2.0 Ti, 0-5.0% W, 0-1.0% Si, and 0.005-0.1% C. The process has been most preferably optimized for an alloy range consisting of 32.0-46% Ni, 19.5-28.0% Cr, 18.0-40.0% Fe, 3.0-8.0% Mo, 1.0-3.0% Cu, 0.6-1.2% Ti, 0.5-2.0% Mn, 0.1-0.5% Si, 0.01-0.08% C. The present invention also includes the pipe made thereby. | 08-15-2013 |
| 20150306710 | High Strength Ni-Cr-Mo-W-Nb-Ti Welding Product and Method of Welding and Weld Deposit Using the Same - A welding filler metal or a welding filler metal product having, in weight percent: 17.0-23.0% chromium, 5.0-12.0% molybdenum, 3.0-11.0% tungsten, 3.0-5.0% niobium, 0-2.0% tantalum, 1.2-3.0% titanium, 0.005-1.50% aluminum, 0.0005-0.100% carbon, <2.0% iron, <5.0% cobalt, and balance nickel wherein the nickel is 56.0-65.0%. A weld deposit formed from the welding filler metal has a minimum yield strength in the as-welded condition of at least 72 ksi (496 MPa). Also, a weld deposit and a method of forming a weld deposit comprising, in weight percent: 17.0-23.0% chromium, 5.0-12.0% molybdenum, 3.0-11.0% tungsten, 3.0-5.0% niobium, 0-2.0% tantalum, 1.2-3.0% titanium, 0.005-1.50% aluminum, 0.0005-0.100% carbon, <8.0% iron, <5.0% cobalt, and balance nickel wherein the nickel is 56.0-65.0%. The weld deposit has a minimum yield strength in the as-welded condition of at least 72 ksi (496 MPa). | 10-29-2015 |
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| 20130021167 | WIRELESS MONITORING AND CONTROL OF SAFETY STATIONS IN A PROCESS PLANT - A safety station for use in a process plant includes one or more leverless limit switches to detect activation of one or more parts of the safety station. The safety station further includes a wireless transmitter coupled to the leverless limit switches to transmit signals associated with the safety station to a base station device, which is communicatively coupled to one or more control and/or monitoring devices. | 01-24-2013 |
| 20130042933 | METHODS AND APPARATUS TO DETERMINE A POSITION OF A VALVE - Methods and apparatus to determine a position of a valve are disclosed. An example apparatus disclosed herein includes a rotary valve assembly and a visual indicator assembly coupled to the rotary valve assembly to indicate a position of a fluid control member of the rotary valve assembly. The visual indicator assembly includes a follower and a shell surrounding the follower. A position of the follower is to correspond to the position of the fluid control member. The example apparatus further includes an electronic position monitor coupled to the shell to determine valve position information based on the position of the follower. | 02-21-2013 |
| 20130049984 | WIRELESS MONITORING SYSTEMS FOR USE WITH PRESSURE SAFETY DEVICES - Wireless monitoring systems for use with pressure safety devices are described. An example wireless monitoring system includes a field device and a wireless transceiver coupled to the field device to receive a signal generated by the field device. The wireless transceiver has a self-contained power module. A wireless interface is communicatively coupled to the wireless transceiver without an interposing intrinsically safe barrier panel. The wireless interface wirelessly receives the signal from the wireless transceiver. | 02-28-2013 |
| 20130125664 | WIRELESS FLOW MONITORING DEVICES - Wireless flow monitoring devices are described. In one example, a device to wirelessly monitor a flow of material is described that includes a housing having a first surface and a second surface opposite the first surface, the second surface having an aperture, a lever secured within the housing to move in response to the flow of material, and a paddle arm forming at least a portion of a first arm of the lever, where an end of the paddle arm extends out the aperture of the second surface of the housing, and where a paddle is affixed to the paddle arm to be positioned within the flow of material. The device includes a magnet that is actuated by a second arm of the lever to move an amount proportional to the first arm of the lever, a portion of the magnet extending beyond the first surface of the housing so that a motion path of the portion of the magnet extending beyond the first surface of the housing is disposed within a channel of a wireless position monitor mounted to the first surface of the housing, where the channel serves as a sensor to detect movement of the magnet. | 05-23-2013 |
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| 20090242384 | Low Pressure Mixing System for Desalting Hydrocarbons - A method and system for reducing the salt content of a crude oil stream includes using a quill to disperse a water stream into the crude oil and then routing the mixed oil/water stream through a plurality of mixing stages. The water stream may include a wash water that has been preconditioned with recycled effluent water. Each mixing stage increases the homogeneity of the mixed oil/water stream. The first and third mixing stages are preferably lower pressure stages relative to the second mixing stage, which provides pressure effective for flowing the mixed oil/water stream through the third and fourth mixing stages. Upon exiting the fourth mixing stage, the mixed oil/water stream is electrostatically treated in a dual frequency separator vessel or a dual polarity separator vessel. | 10-01-2009 |
| 20130082005 | Method to Process Effluent Brine and Interface Rag from an Oil Dehydration/Desalting System - A method for processing interface emulsion, water, and solids contained within a separator vessel that comprises the steps of continually extracting those components from the vessel and then passing them through a gas flotation cell. The cell, which is preferably a vertical induced gas flotation cell, separates the oil and water contained in the interface emulsion and discharges recovered oil from an upper portion of the cell and treated water from a bottom portion of the cell. The recovered oil and treated water may be further processed and recycled to the vessel or sent elsewhere. The treated water may also be recycled to the cell or sent to a process sewer. Fuel gas residing in an upper portion of the cell may be cooled and passed through a splitter. All the steps of the method comprise a closed system with no air emissions. | 04-04-2013 |
| 20130083620 | Interface and Mud Control System and Method for Refinery Desalters - A method and system for controlling an interface emulsion layer and mud layer within a desalter vessel includes injecting a water flow through a plurality of nozzles arranged about a piping circuit located in the brine water layer. Each nozzle is oriented toward an interior space of the desalter vessel and is arranged oblique to the piping circuit. The water flow through the plurality of nozzles causes a horizontal and vertical rotation of a volume of water that is effective for suspending solids in the water and promoting a collapse of the interface emulsion layer. The water flow through each nozzle, which may be a recycled water flow, is preferably in a range of 1 to 3 fpm and each nozzle is preferably oriented at an angle of about 15° and 60° in a horizontal plane and a downward angle of about 15° and 60° in a vertical plane. | 04-04-2013 |
| 20130175203 | Method for Separating Entrained Catalyst and Catalyst Fines from Slurry Oil - A method for removing catalyst, catalyst fines, and coke particulates from a slurry oil stream includes the steps of routing a first slurry oil stream from a first slurry oil source to at least one hydrocyclone, increasing at least one of a temperature and a pressure of the first slurry oil stream prior to it entering the at least one hydrocyclone; passing the first slurry oil stream through the at least one hydrocyclone; and routing a second slurry oil stream exiting an overflow end of the at least one hydrocyclone to a second slurry oil source. The first and second slurry oil sources may be one or more of the following: a main column of a fluid catalytic cracking fractionator, a steam generator, a heat exchanger, a decant slurry oil storage, and a slurry oil storage tank. | 07-11-2013 |
| 20140110220 | Interface and Mud Control System and Method For Refinery Desalters - A method and system for controlling an interface emulsion layer and mud layer within a desalter vessel includes injecting a water flow through a plurality of nozzles arranged about a piping circuit located in the brine water layer. Each nozzle is oriented toward an interior space of the desalter vessel and is arranged oblique to the piping circuit. The water flow through the plurality of nozzles causes a horizontal and vertical rotation of a volume of water that is effective for suspending solids in the water and promoting a collapse of the interface emulsion layer. The water flow through each nozzle, which may be a recycled water flow, is preferably in a range of 1 to 3 fpm and each nozzle is preferably oriented at an angle of about 15° and 60° in a horizontal plane and a downward angle of about 15° and 60° in a vertical plane. | 04-24-2014 |
| 20150083648 | SYSTEM TO PROCESS EFFLUENT BRINE AND INTERFACE RAG FROM AN OIL DEHYDRATION / DESALTING SYSTEM - A method system for processing interface emulsion, water, and solids contained within a separator vessel that comprises the steps of continually extracting those components from the vessel and then passing them through a gas flotation cell. The cell, which is preferably a vertical induced gas flotation cell, separates the oil and water contained in the interface emulsion and discharges recovered oil from an upper portion of the cell and treated water from a bottom portion of the cell. The recovered oil and treated water may be further processed and recycled to the vessel or sent elsewhere. The treated water may also be recycled to the cell or sent to a process sewer. Fuel gas residing in an upper portion of the cell may be cooled and passed through a splitter. All the steps of the system comprise a closed system with no air emissions. | 03-26-2015 |
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| 20080218354 | NON-NETWORKED RFID SYSTEM - Non-networked radio frequency identification (RFID) systems and methods are described that use RFID tags to exchange information between non-networked RFID readers. The RFID tags may store information about conditions the RFID-tagged items have encountered while being processed. RFID readers may dynamically update the information stored on the RFID tags as the RFID-tagged items are processed at nodes. An RFID tag may include a processor that dynamically determines process control instructions based on the information. | 09-11-2008 |
| 20080258875 | RADIO FREQUENCY IDENTIFICATION FUNCTIONALITY COUPLED TO ELECTRICALLY CONDUCTIVE SIGNAGE - The present disclosure relates to multiple embodiments of a signage having radio-frequency responsive features, methods of making and using the signage, and the performance characteristics of the signage. These embodiments include a cutout, aperture, or opening in an electrically conductive sign into which or adjacent to which is placed an RFID tag or chip. | 10-23-2008 |
| 20090160638 | RADIO FREQUENCY IDENTIFICATION READER SYSTEM - In general, the disclosure describes a radio frequency identification (“RFID”) reader system is disclosed. In particular, the RFID reader system is preferably mobile and determines both the existence and general location of at least one RFID-tagged object of interest. | 06-25-2009 |
| 20090167502 | Device for verifying a location and functionality of a radio-frequency identification (RFID) tag on an item - A Radio-Frequency Identification (RFID) system verifies proper placement and functionality of RFID tags with respect to particular end-use RFID systems at the time the RFID tag is applied to an item but before the item is deployed. A device for verifying a location and functionality of an RFID tag on an item includes an item holder, a power coupling mechanism attached to the item holder, and an RFID reader electrically connected to the power coupling mechanism. The power coupling mechanism creates a near field for transmission of read or write commands from the RFID reader to an RFID tag on an item placed on the item holder to verify the location and functionality of the RFID tag as applied to the item with respect to a near-field coupling mechanism of a particular end-use RFID system. The device may include additional power coupling mechanisms for testing the functionality of the tag. | 07-02-2009 |
| 20090321529 | RADIO FREQUENCY IDENTIFICATION FUNCTIONALITY COUPLED TO ELECTRICALLY CONDUCTIVE SIGNAGE - The present disclosure relates to multiple embodiments of a signage having radio-frequency responsive features, methods of making and using the signage, and the performance characteristics of the signage. These embodiments include a cutout, aperture, or opening in an electrically conductive element into which or adjacent to which is placed an RFID tag or chip. | 12-31-2009 |
| 20100123553 | RFID TAG ANTENNA WITH CAPACITIVELY OR INDUCTIVELY COUPLED TUNING COMPONENT - This disclosure describes RFID tags designed to provide improved impedance matching capabilities. An RFID tag may include a radiating component and a tuning component located on different layers of the RFID tag. The radiating component and tuning component are located proximate to one another to provide a proximate coupling (e.g., an inductive and/or capacitive coupling). In one embodiment, at least a portion of the radiating component of a first layer overlaps at least a portion of the tuning component of a second layer, resulting in a proximate coupling. The tuning component may be used for tuning the antenna, e.g., matching an impedance of the radiating element and an IC chip electrically connected to the tuning component. Because the radiating element does not have to be designed to match impedances, the radiating element may be designed to provide better gain, polarization purity, larger radar cross section or other antenna parameters. | 05-20-2010 |
| 20120286691 | Method, Apparatus, and System for Supplying Pulsed Current to a Load - Supplying pulsed current to a load involves repeatedly driving an electrical load between successive active and idle states via a regulator that includes a switched mode power supply. The regulator receives input current from a direct current power source and provides output current to at least an energy storage device in the idle states of the electrical load. The energy storage device is coupled to the load and the regulator. Output current is provided from both the regulator and the energy storage device to the electrical load in the active states of the electrical load. A storage capacity of the energy storage device is selected so that a duty cycle of the input current is greater than a duty cycle of the output current. | 11-15-2012 |
| 20120320103 | Controlling Light Sources for Colour Sequential Image Displaying - Color sequential imaging involves illuminating, for each of two or more time-separated color fields, two or more light sources. Each of the two or more light sources emits at different wavelengths, and at least one of the first or second light sources is activated at different, non-zero current amplitudes during each of the first and second color fields. The color fields are projected via a spatial light modulator in synchronization with the activation of the at least one of the first or second light sources. | 12-20-2012 |
| 20130222237 | INTERACTIVE POLARIZATION-PRESERVING PROJECTION DISPLAY - The disclosure generally relates to optical devices, such as interactive displays, and in particular to interactive projection displays having passive input devices. The present disclosure also provides a passive interactive input device having the ability to overcome problematic ambient interference signals in an interactive display, such as an interactive projection display. | 08-29-2013 |
| 20130222892 | INTERACTIVE POLARIZATION-SELECTIVE PROJECTION DISPLAY - The disclosure generally relates to optical devices, such as interactive displays, and in particular to interactive projection displays having passive interactive input devices. The present disclosure also provides a passive interactive input device ( | 08-29-2013 |
| 20140141725 | WIRELESS PRESENTATION SYSTEM ALLOWING AUTOMATIC ASSOCIATION AND CONNECTION - A wireless presentation system includes communication means for line-of-sight communication links such that an association between a content holder and a desired presentation device can be automatically established using line-of-sight communication links. | 05-22-2014 |
| 20150035716 | SINGLE TURN MAGNETIC DRIVE LOOP FOR ELECTRONIC ARTICLE SURVEILLANCE - A single turn loop electronic article surveillance (EAS) gate. The gate includes a closed magnetic core, a multi-turn primary winding wound around the core, and a secondary loop passing through the core once. The secondary loop is a self-supporting single turn loop, and the secondary loop is a transmit loop that generates a magnetic drive field for the article detection gate system. | 02-05-2015 |
| 20150091799 | PROJECTOR WITH REMOVABLE MODULE - A projector ( | 04-02-2015 |
| 20150160741 | DEVICE ALLOWING TOOL-FREE INTERACTIVITY WITH A PROJECTED IMAGE - Devices that provide for interaction with an image are disclosed. More specifically, devices that provide for tool-free interaction with a projected image are disclosed. | 06-11-2015 |
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| 20090327117 | Apparatus and Method for Trade Aggregation of Trade Allocations and Settlements - A post-trade aggregation system includes an allocation middleware interface, which interacts with an order management system to allocate and settle trades. The order management system receives a trade order on behalf of a customer and either apportions the trade into a plurality of smaller orders and communicates them to a plurality of order destinations directly (e.g. via the FIX protocol), or sends large orders to an order staging and optimization interface which then apportions the larger orders into a plurality of smaller orders and communicates the orders to a plurality of order destinations. The post-trade aggregation system contains an allocation middleware interface which receives the individual trade executions from the plurality of order destination and compresses them into a single average-priced block. The allocation middleware interface then sends the single average-priced block to be cleared by a designated clearing agent and allocates the single average-priced block into one or more custodian accounts. In further aspects, a method and apparatus are also provided. | 12-31-2009 |
| 20100332375 | Apparatus and Method for Trade Aggregation of Trade Allocations and Settlements - A post-trade aggregation system includes an allocation middleware interface, which interacts with an order management system to allocate and settle trades. The order management system receives a trade order on behalf of a customer and either apportions the trade into a plurality of smaller orders and communicates them to a plurality of order destinations directly (e.g. via the FIX protocol), or sends large orders to an order staging and optimization interface which then apportions the larger orders into a plurality of smaller orders and communicates the orders to a plurality of order destinations. The post-trade aggregation system contains an allocation middleware interface which receives the individual trade executions from the plurality of order destination and compresses them into a single average-priced block. The allocation middleware interface then sends the single average-priced block to be cleared by a designated clearing agent and allocates the single average-priced block into one or more custodian accounts. In further aspects, a method and apparatus are also provided. | 12-30-2010 |
| 20130144773 | APPARATUS AND METHOD FOR TRADE AGGREGATION OF TRADE ALLOCATIONS AND SETTLEMENTS - A post-trade aggregation system for financial instrument trading systems, wherein a trader manages a plurality of trade orders to be executed by one or more executing brokers on behalf of customers via a data interface system. The plurality of trade orders includes at least one wrap block order and at least one institutional block order. The plurality of trade orders are merged into a single merged block order, apportioned into a plurality of smaller electronic trade orders, and transmitted to a plurality of order destinations. One or more computer systems are in electronic communication with the data interface system and with a clearing system, and configured to compress individual executions from the plurality of order destinations corresponding to the plurality of smaller electronic trade orders into a single net marked-up step-out for wrap orders and a single average-priced block for institutional orders. | 06-06-2013 |
| 20150178839 | APPARATUS AND METHOD FOR TRADE AGGREGATION OF TRADE ALLOCATIONS AND SETTLEMENTS - A post-trade aggregation system includes an allocation middleware interface, which interacts with data interface to allocate and settle trades. An order management system receives a trade order on behalf of a customer and causes apportionment of the trade into a plurality of smaller orders to be transmitted to a plurality of order destinations directly (e.g. via the FIX protocol). The post-trade aggregation system includes an allocation middleware interface which receives the individual trade executions from the plurality of order destination and compresses them into a single average-priced block. The allocation middleware interface then transmits the single average-priced block to be cleared by a designated clearing agent and allocates the single average-priced block into one or more custodian accounts. | 06-25-2015 |
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| 20100071690 | Face warming breath deflecting apparatus - A thermally active breath deflecting apparatus having a flexible base of sufficient width to extend at least to and between the corner portions of the eyes and of sufficient length to extend at least from immediately below the eyes to at least beyond the tip of the nose such that breath from the mouth and nose is prevented from traveling upwardly over the eyes. The apparatus includes a thermal pack that can warm or cool the face. The thermal pack is preferably a heat pack. In an alternate embodiment, the flexible base can include medication such as a decongestant. | 03-25-2010 |
| 20100076532 | Face warming breath deflecting apparatus - A thermally active breath deflecting apparatus having a flexible base of sufficient width to extend at least to and between the corner portions of the eyes and of sufficient length to extend at least from immediately below the eyes to at least beyond the tip of the nose such that breath from the mouth and nose is prevented from traveling upwardly over the eyes. The apparatus includes a thermal pack that can warm or cool the face. The thermal pack is preferably a heat pack. | 03-25-2010 |
| 20110061656 | Face Mask With Seal Within Seal And Optional Bridging Seal - The present face mask may have a double seal, a triple seal or a quadruple seal, with distinct spacing between each of the seals within a set of seals. Each of the seals within a double seal, triple seal, or quadruple seal may stand alone or may be interconnected to other seals by bridging, where such bridging is formed of the same adhesive as the seal itself. Also disclosed is an after market embodiment where a multiple seal by itself is housed between two sheets of release paper to be applied to a face mask by the user himself when needed. Further disclosed is a multiple seal with bridging applied to a clothing combination, such as to seal sleeve cuffs to a glove. | 03-17-2011 |
| 20110061657 | Face Mask With Seal Within Seal And Optional Bridging Seal - The present face mask may have a double seal, a triple seal or a quadruple seal, with distinct spacing between each of the seals within a set of seals. Each of the seals within a double seal, triple seal, or quadruple seal may stand alone or may be interconnected to other seals by bridging, where such bridging is formed of the same adhesive as the seal itself. Also disclosed is an after market embodiment where a multiple seal by itself is housed between two sheets of release paper to be applied to a face mask by the user himself when needed. Further disclosed is a multiple seal with bridging applied to a clothing combination, such as to seal sleeve cuffs to a glove. | 03-17-2011 |
| 20130180529 | Face mask with seal within seal and optional bridging seal - The present face mask may have a double seal, a triple seal or a quadruple seal, with distinct spacing between each of the seals within a set of seals. Each of the seals within a double seal, triple seal, or quadruple seal may stand alone or may be interconnected to other seals by bridging, where such bridging is formed of the same adhesive as the seal itself. Also disclosed is an after market embodiment where a multiple seal by itself is housed between two sheets of release paper to be applied to a face mask by the user himself when needed. Further disclosed is a multiple seal with bridging applied to a clothing combination, such as to seal sleeve cuffs to a glove. | 07-18-2013 |
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| 20080281630 | PRESCRIPTION COMPLIANCE MONITORING SYSTEM - A method for monitoring patient compliance to medical therapy that includes repeatedly measuring therapy compliance of a patient, uploading the therapy compliance measurements to a personal computer, connecting a central server using the personal computer, sending the uploaded therapy compliance measurements from the personal computer to the central server, providing a number of predetermined compliance threshold amounts, comparing the sent therapy compliance measurements with the number of predetermined compliance thresholds corresponding to the patient, determining a need and level of intervention based on the result of the comparing and reporting the determined need for intervention to a health professional corresponding to the patient and determined level. | 11-13-2008 |
| 20110196700 | PRESCRIPTION COMPLIANCE MONITORING SYSTEM - A method for monitoring patient compliance to medical therapy that includes repeatedly measuring therapy compliance of a patient, uploading the therapy compliance measurements to a personal computer, connecting a central server using the personal computer, sending the uploaded therapy compliance measurements from the personal computer to the central server, providing a number of predetermined compliance threshold amounts, comparing the sent therapy compliance measurements with the number of predetermined compliance thresholds corresponding to the patient, determining a need and level of intervention based on the result of the comparing and reporting the determined need for intervention to a health professional corresponding to the patient and determined level. | 08-11-2011 |
| 20130054346 | PROVIDING HIPPA COMPLIANT TARGETED ADVERTISING TO PATIENT - A method for providing HIPAA and HITECH compliant targeted advertising to patients. The method including receiving information for posting and target audience criteria from a client entity, identifying, without disclosing any medical information to the client entity, a subset of patients which meet the received target audience criteria by searching the medical records of the plurality of patients, processing the information for the subset of patients, generating and sending an electronic message to the subset of patients identified by the identifying, which notifies the subset of patients that an opportunity exists and is accessible via a website, without specifically identifying the opportunity and in response to the completion of the processing, displaying a portion of the information to each of the subset of the patients which logs into the website and enabling a second portion of the information to be accessed in response to a selection on the website. | 02-28-2013 |
| 20150086494 | TOPICAL TREATMENTS INCORPORATING CANNABIS SP. DERIVED BOTANICAL DRUG PRODUCT - A topical formulation comprising a | 03-26-2015 |
| 20150290267 | TOPICAL TREATMENTS INCORPORATING CANNABIS SP. DERIVED BOTANICAL DRUG PRODUCT - A topical formulation comprising a | 10-15-2015 |
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| 20080215289 | PRESCRIPTION COMPLIANCE DEVICE AND METHOD OF USING DEVICE - A prescription compliance device which aids patients in complying with instructions given by a physician for taking prescription medication. The device reminds a patient when the next dose of medication is to be taken and indicates whether a specified dose has been taken. The device includes a microcontroller, a display, a program memory for storing pre-programmed medication-taking regimens for single and multiple medications, a real time clock, a selector for selecting one of the regimens and for programming the device as to the time and day on which a first dose of medication is to be taken, a display which alternately displays the current time and a time at which a next dose of medication is to be taken and an alarm which alerts the patient at times when a dose of medication is to be taken. The selector includes an event switch which is activated by the patient after taking a dose of medication so as to record the taking of medication and to cause the microcontroller to effect the display of the next time at which a dose of medication is to be taken. A memory may also be included to record the times at which a patient takes doses of medication. The device also includes a remote programming feature via a wireless link. | 09-04-2008 |
| 20100045466 | PRESCRIPTION COMPLIANCE DEVICE AND METHOD OF USING DEVICE - A prescription compliance device which aids patients in complying with instructions given by a physician for taking prescription medication. The device reminds a patient when the next dose of medication is to be taken and indicates whether a specified dose has been taken. The device includes a microcontroller, a display, a program memory for storing pre-programmed medication-taking regimens for single and multiple medications, a real time clock, a selector for selecting one of the regimens and for programming the device as to the time and day on which a first dose of medication is to be taken, a display which alternately displays the current time and a time at which a next dose of medication is to be taken and an alarm which alerts the patient at times when a dose of medication is to be taken. The selector includes an event switch which is activated by the patient after taking a dose of medication so as to record the taking of medication and to cause the microcontroller to effect the display of the next time at which a dose of medication is to be taken. A memory may also be included to record the times at which a patient takes doses of medication. The device also includes a remote programming feature via a wireless link. | 02-25-2010 |
| 20110193705 | PRESCRIPTION COMPLIANCE DEVICE AND METHOD OF USING DEVICE - A prescription compliance device which aids patients in complying with instructions given by a physician for taking prescription medication. The device reminds a patient when the next dose of medication is to be taken and indicates whether a specified dose has been taken. The device includes a microcontroller, a display, a program memory for storing pre-programmed medication-taking regimens for single and multiple medications, a real time clock, a selector for selecting one of the regimens and for programming the device as to the time and day on which a first dose of medication is to be taken, a display which alternately displays the current time and a time at which a next dose of medication is to be taken and an alarm which alerts the patient at times when a dose of medication is to be taken. The selector includes an event switch which is activated by the patient after taking a dose of medication so as to record the taking of medication and to cause the microcontroller to effect the display of the next time at which a dose of medication is to be taken. A memory may also be included to record the times at which a patient takes doses of medication. The device also includes a remote programming feature via a wireless link. | 08-11-2011 |
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| 20090287190 | TISSUE TRANSFER METHOD AND APPARATUS - A system in accordance with embodiments of the present invention includes a cannula interconnected to a collection vessel by a flexible conduit. The collection vessel can comprise an impermeable or permeable collection vessel. The collection vessel is contained within a collection container, and can feature a tapered end. An air inlet may be provided in the flexible conduit and/or in a collection canister lid. | 11-19-2009 |
| 20100280496 | TISSUE TRANSFER CANNULA - Cannula and handle systems and cannulas having substantially continuous interior pathways or channels are provided. The interior pathway may extend from the inlet to the cannula to the outlet, such that tissue collected at the inlet is carried to the outlet without contacting other components. Moreover, the substantially continuous nature of the interior pathway, with an absence of drop-offs, blind pockets or other discontinuities, facilitates cleaning. In addition, inlet holes are sized to promote the transfer of tissue through the channel to the outlet, and to the avoidance of damaging collected tissue. | 11-04-2010 |
| 20130138053 | TISSUE TRANSFER CANNULA - Cannula and handle systems and cannulas having substantially continuous interior pathways or channels are provided. The interior pathway may extend from the inlet to the cannula to the outlet, such that tissue collected at the inlet is carried to the outlet without contacting other components. Moreover, the substantially continuous nature of the interior pathway, with an absence of drop-offs, blind pockets or other discontinuities, facilitates cleaning. In addition, inlet holes are sized to promote the transfer of tissue through the channel to the outlet, and to avoid damaging collected tissue. Holes included in the inlet can be oblong, and can be slanted with respect to a longitudinal axis of the cannula. | 05-30-2013 |
| 20140130936 | SYRINGE FILL METHOD AND APPARATUS - Tissue collection systems and methods are provided. More particular, a modular system including one or more manifold elements is provided. Each manifold element includes a manifold barrel and a coupler to which a syringe body can be connected. An inlet of a first manifold element is connected to a first manifold cap having an inlet orifice. A second manifold cap having an outlet orifice is connected to the outlet of the first manifold element or to the outlet of a second manifold element. The manifold barrel can include a barrel inlet that is offset from a barrel outlet. | 05-15-2014 |
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| 20090145067 | COMPOSITION, METHOD OF USE, AND STRUCTURAL BARRIER SYSTEM - An environmental barrier composition and method of use for forming a structural barrier system to seal structural openings such as doors and windows is provided. The composition includes a liquid rosin that is silyl-terminated polyether, a filler material, and a curing catalyst. The method includes applying the composition to a prepared through-hole in combination with flashing material at least along a bottom surface of the through-hole and installation of a window or door into the prepared through-hole to form a barrier system in which a continuous film can be easily inspected, is waterproof, meet air barrier requirements of ASTM E2178, has elastomeric properties, allows substrate expansion, contraction, and movement, does not shrink or lose volume as it cures, and cures rapidly with sufficient adhesion to transition flashing to incorporate into a designed drainage plane and allow integration of a continuous air barrier system where the barrier is at least semi-vapor-permeable. | 06-11-2009 |
| 20110072747 | COMPOSITION, METHOD OF USE, AND STRUCTURAL BARRIER SYSTEM - An environmental barrier composition and method of use for forming a structural barrier system to seal structural openings such as doors and windows is provided. The composition includes a liquid rosin that is silyl-terminated polyether, a filler material, and a curing catalyst. The method includes applying the composition to a prepared through-hole in combination with flashing material at least along a bottom surface of the through-hole and installation of a window or door into the prepared through-hole to form a barrier system in which a continuous film can be easily inspected, is waterproof, meet air barrier requirements of ASTM E2178, has elastomeric properties, allows substrate expansion, contraction, and movement, does not shrink or lose volume as it cures, and cures rapidly with sufficient adhesion to transition flashing to incorporate into a designed drainage plane and allow integration of a continuous air barrier system where the barrier is at least semi-vapor-permeable. | 03-31-2011 |
| 20120317896 | STRUCTURAL BARRIER SYSTEM - An environmental barrier composition and method of use for forming a structural barrier system to seal structural openings such as doors and windows is provided. The composition includes a liquid rosin that is silyl-terminated polyether, a filler material, and a curing catalyst. The method includes applying the composition to a prepared through-hole in combination with flashing material at least along a bottom surface of the through-hole and installation of a window or door into the prepared through-hole to form a barrier system in which a continuous film can be easily inspected, is waterproof, meet air barrier requirements of ASTM E2178, has elastomeric properties, allows substrate expansion, contraction, and movement, does not shrink or lose volume as it cures, and cures rapidly with sufficient adhesion to transition flashing to incorporate into a designed drainage plane and allow integration of a continuous air barrier system where the barrier is at least semi-vapor-permeable. | 12-20-2012 |
| 20130276405 | STRUCTURAL BARRIER SYSTEM - An environmental barrier composition and method of use for forming a structural barrier system to seal structural openings such as doors and windows is provided. The composition includes a liquid rosin that is silyl-terminated polyether, a filler material, and a curing catalyst. The method includes applying the composition to a prepared through-hole in combination with flashing material at least along a bottom surface of the through-hole and installation of a window or door into the prepared through-hole to form a barrier system in which a continuous film can be easily inspected, is waterproof, meet air barrier requirements of ASTM E2178, has elastomeric properties, allows substrate expansion, contraction, and movement, does not shrink or lose volume as it cures, and cures rapidly with sufficient adhesion to transition flashing to incorporate into a designed drainage plane and allow integration of a continuous air barrier system where the barrier is at least semi-vapor-permeable. | 10-24-2013 |
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| 20080242726 | Trans-Clomiphene for the Treatment of Benign Prostate Hypertrophy, Porstate Cancer, Hypogonadism Elevated Triglycerides and High Cholesterol - Compositions comprising trans-clomiphene may be used in treating benign prostate hypertrophy, prostate cancer, elevated triglyceride levels and hypogonadism. | 10-02-2008 |
| 20090118253 | COMPOSITIONS AND METHODS FOR TREATING DYSFUNCTIONAL UTERINE BLEEDING - The subject matter of the instant invention is pertinent to the field of hormone therapy. More specifically, the subject matter of the instant invention concerns methods of treating dysfunctional uterine bleeding. The instant invention is also relevant to the treatment and/or prevention of anemia in patients with dysfunctional uterine bleeding. Compositions for practicing the methods, comprising progesterone antagonists are also disclosed. Embodiments of the instant invention also disclose methods for identifying new selective progesterone receptor modulators for practicing disclosed methods of treatment. | 05-07-2009 |
| 20110053900 | PROGESTERONE ANTAGONISTS SUCH AS CDB-4124 IN THE TREATMENT OF BREAST CANCER - The subject matter of the instant invention is pertinent to the field of cancer treatment. In particular, the instant invention is relevant to the treatment and/or prevention of breast cancer in a patient. Compositions for practicing the methods, comprising selective progesterone receptor modulators, which function as progesterone agonists in the uterus and as progesterone antagonists in the breast tissue and exhibit only low affinity for glucocorticoid and estrogen receptors, are also disclosed. Embodiments of the instant invention also disclose methods for preventing the development of breast cancer in patients undergoing hormone replacement therapy or estrogen therapy. | 03-03-2011 |
| 20130018027 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS - The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. New compounds and methods for treating these conditions are disclosed. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation. | 01-17-2013 |
| 20130274234 | NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS - The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. New compounds and methods for treating these conditions are disclosed. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation. | 10-17-2013 |
| 20140163114 | TRANS-CLOMIPHENE METABOLITES AND USES THEREOF - The present invention relates to substantially pure metabolites of irara-clomiphene. The invention is also directed to pharmaceutical compositions comprising these metabolites and their use in treating disorders including secondary hypogonadism, type 2 diabetes, elevated cholesterol, elevated triglycerides, wasting, lipodystrophy, female and male infertility, benign prostate hypertrophy, prostate cancer, breast cancer, ovarian cancer and endometrial cancer. | 06-12-2014 |
| 20140343022 | Progesterone Antagonists such as CDB-4124 in the Treatment of Breast Cancer - The subject matter of the instant invention is pertinent to the field of cancer treatment. In particular, the instant invention is relevant to the treatment and or prevention of breast cancer in a patient. Compositions for practicing the methods, comprising selective progesterone receptor modulators, which function as progesterone agonists in the uterus and as progesterone antagonists in the breast tissue and exhibit only low affinity for glucocorticoid and estrogen receptors, are also disclosed. Embodiments of the instant invention also disclose methods for preventing the development of breast cancer in patients undergoing hormone replacement therapy or estrogen therapy. | 11-20-2014 |
| 20150031656 | COMBINATION THERAPY FOR TREATING ANDROGEN DEFICIENCY - The present invention relates to a combination therapy for elevating testosterone levels in male mammals in which an antiestrogen or pharmaceutically acceptable salt thereof is co-administered to the mammal with an additional therapeutic agent selected from an androgen and an aromatase inhibitor. The invention is also directed to a combination therapy for treating males with hypogonadism and disorders related thereto, including reduction of muscle mass. limitation of body performance capacity, reduction of bone density, reduction of libido, reduction of potency, reduction of benign prostatic hyperplasia and infertility. | 01-29-2015 |
| 20150031680 | Selective Estrogen Receptor Modulators With Short Half-Lives and Uses Thereof - The present invention relates to the long-term administration of a selective estrogen receptor modulator (SERM) with a short half-life for the treatment of a variety of estrogen receptor-mediated conditions. The SERM may be administered at a concentration at or below that of a SERM with a long half-life in order to achieve an equivalent therapeutic effect. | 01-29-2015 |
| 20150203526 | NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS - The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. New compounds and methods for treating these conditions are disclosed. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation. | 07-23-2015 |
| 20150283099 | Trans-Clomiphene for Use in Cancer Therapy - The present invention relates to the administration of compositions comprising an antiestrogen, preferably a selective estrogen receptor modulator (SERM) such as trans-clomiphene, for treating cancer and associated diseases. The invention is also directed to methods for reducing IGF-1 levels in a subject in need thereof by administering a composition comprising an antiestrogen, preferably a SERM such as trans-clomiphene. | 10-08-2015 |
| 20150297612 | METHODS AND COMPOSITIONS FOR TREATING PROGESTERONE-DEPENDENT CONDITIONS - The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. Methods for treating these conditions are provided comprising systemically administering an antiprogestin and contemporaneously locally administering an antiprogestin. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation. | 10-22-2015 |
