Patent application number | Description | Published |
20100022623 | Methods and Compositions for the Treatment of Eye Disorders with Increased Intraocular Pressure - The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention. | 01-28-2010 |
20100331394 | Methods and Compositions for the Treatment of Eye Disorders with Increased Intraocular Pressure - The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention. | 12-30-2010 |
20110313016 | Treatment of Intestinal Conditions - Methods and compositions for the treatment of intestinal disorders, such as IBD and Crohn's disease, are disclosed. Preferred compositions include siNA. Also disclosed is a method of specifically targeting siNA to treat intestinal disorders by intrarectal administration of siNA compounds. | 12-22-2011 |
Patent application number | Description | Published |
20100304899 | Leg Gloves with Downward Diagonal Facing Pocket Openings - A leg glove, or leg mitten, having pockets for the hands of a lifter used when lifting a person who is jumping or being lifted, especially for lineouts in Rugby Union. The leg glove pockets have downward diagonal facing pocket openings. The simple, reusable, easy to use leg glove provides a level of effectiveness, comfort, convenience, and safety not provided by conventional methods. The leg glove is simply made from a single piece of flexible, elastic material, such as neoprene. A fold creates a base layer and a partially overlapping pocket layer. The pocket is secured and held open with a pocket attachment and base attachment forming pocket openings. The pocket openings are configured to face downward on a diagonal. An improved leg glove further comprises a non-elastic base strap. To use, leg gloves are applied to the legs of a jumper. When the jumper jumps, one or more lifters place their hands in the leg glove pockets. The lifters lift the jumper higher, support the jumper in the jump while the jumper attempts to intercept a ball, and safely lower the jumper. In some embodiments, the pocket attachment is shaped like a question mark matching the shape of the inserted fingers, palm, and thumb of the lifter's hand. | 12-02-2010 |
20100321466 | Handheld Wireless Digital Audio and Video Receiver - A handheld, wireless digital audio and/or video device that receives compressed media, decompresses the compressed media, and plays and/or displays the decompressed media. The receiver may be part of a system of handheld, wireless devices that compress, enhance, encode, transmit, decompress and display digital video images in real time. An enhanced iPod-type device includes wireless and/or cellular communications, a high-resolution display and a high-resolution video camera. Real time wireless videoconferences connect multiple handheld video devices. Real time compression and real time transmission is achieved. Real time decompression is achieved by decoding and decompressing the encoded data to display high quality images. A zoom control can be used select a portion of interest of video being captured and/or transmitted. The receiver may also have a touch sensitive display screen providing controls for video display and mobile telephone operation. In one embodiment, a handheld, wireless digital audio device is configured to receive compressed audio data from either a wireless satellite network or a wireless Internet data network. | 12-23-2010 |
20110108078 | Blinds and Shelters with Flexible and Dynamic Configurations - An easy to use, universal, simple, lightweight, compact, portable, dynamically configurable system of concealment and shelter. An operator configures a number of concealment blinds or shelters using shafts and covers or shells. Some embodiments include user adjustable domes. A hubless, dynamic blind or shelter comprises two or more cover shafts and an adjustable strap which provides a freestanding, flexible frame. The frame is covered with a cover or skin. The cover adjusts to the dynamic changes in the frame. In one embodiment the cover is an elastic net that changes shape but maintains tight skin. In another embodiment the cover has expansion panels and lace. Embodiments include layout blinds and boat blinds which incorporate a quick release clip | 05-12-2011 |
20110294611 | Lightweight Portable Goal Post - Low cost, durable, reusable, lightweight, inexpensive, simple, easy to assemble/disassemble, transportable goal posts. Each goal posts may be composed of single piece T reinforcements and a single piece cross bar reinforcement, as well as readily available construction materials, such as PVC pipe. The bodies of the single piece reinforcements are sized so that the pipes forming the upright posts and crossbar have the same length. Assembly, disassembly, and transportation are simplified. The disassembled components can be carried in vans and SUVs. Internal reinforcements allow flexible, low cost materials such as PVC pipe to be used while maintaining a professional, aesthetic appearance. | 12-01-2011 |
20110320413 | Detection of Obscured Copying Using Discovered Translation Files and Other Operation Data - Systems and methods that automatically compare sets of files to determine what has been copied even when sophisticated techniques for hiding or obscuring the copying have been employed. The file compare system comprises a file compare program that uses various operational data and user interface options to detect illicit copying, highlight and align matching lines, and to produced a formatted report. A discovered translations file is used to match translated tokens. Other operation data files specify rules that the file program then uses to improve its results. The generated report contains statistics and full disclosures of the discovered translations used and the other methods used in creating the exhibits. The system includes a bulk compare program that automatically detects likely file pairings and candidates for validation as suspected translations, which can be used on iterative runs. The user is given full control in the final output and the system automatically reforms the reports and recalculations the statistics for consistent and accurate final presentation. | 12-29-2011 |
20120046100 | Display, Device, Method, and Computer Program for Indicating a Clear Shot - An improved display provides information regarding a projectile trajectory so that a user is informed whether or not there is a clear shot. Such information facilitates accurate, effective, and safe firearm and bow use by providing indications regarding obstacles that are between the shooter and target and which may or may not be in the projectile trajectory. The improved display provides one or more path indicators shown over the cross hairs. In some embodiments the highest point in the projectile trajectory (being a true aim point) is indicated in relation to the visualized target and possible obstacles. An improved rangefinder device generally includes a range sensor operable to determine a first range to a target, a tilt sensor operable to determine an angle to the target relative to the device, and a computing element, coupled with the range sensor and the tilt sensor, operable to determine an accurate projectile trajectory based on the first range and the determined angle. In some embodiments any obstacle in the projectile trajectory is automatically ranged and an indication is provided that the obstacle will interfere with the clear shot. A game display embodiment provides education regarding the technology. Enhanced rangefinders have digital cameras and high-resolution displays. Some embodiments adapt a mobile smart device such as an iPhone with a range sensor to be a high resolution rangefinder with a touch screen, GPS, and video analysis capabilities. | 02-23-2012 |
20120112516 | Devices for Seat Belt Shoulder Strap Comfort and Safety - Seat belt shoulder strap comfort and safety devices provide increased comfort and safety for the user. Embodiments of adjustable clips allow positioning of the clip on the seat belt shoulder strap away from the neck and onto the torso minimizing neck or head injury in an accident or near accident also allowing for focus to be maintained on the road or matters that require attention. Embodiments of two channeled clips provide one channel for the shoulder strap and another channel for the waist strap and are designed to guide the should strap in a comfortable direction while reducing the force on the adjustable clip and the passenger. Embodiments of adjustable clips with locking mechanism are combined with a two channeled clip for optimum safety, comfort, and durability. Some embodiments allow for easy installation and removal or adjustment, which allows the seat belt to be fully retracted and not left dangling. | 05-10-2012 |
20130059632 | Display, Device, Method, and Computer Program for Indicating a Clear Shot - A system for indicating to a user a clear shot along a projectile trajectory to a target wherein one of the trajectory path indicators indicates a height of the projectile trajectory at a predetermined intermediate range to the target whereby the user is informed regarding whether or not an obstacle is in the projectile trajectory. The system facilitates accurate, effective, and safe firearm and bow use by providing indications regarding obstacles that are between the shooter and target and which may or may not be in the projectile trajectory. The system may indicate a calibrated aiming point, which is the maximum height of the projectile trajectory. Enhanced rangefinders have digital cameras and high-resolution displays. Some embodiments include a weapon scope, a simulation game device, and a mobile smart phone. A method of using the system. | 03-07-2013 |