Rohrer, US
Baerbel Rohrer, Mt. Pleasant, SC US
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20110130345 | ALPHA CONNEXIN C-TERMINAL (ACT) PEPTIDES FOR TREATING AGE-RELATED MACULAR DEGENERATION - Provided herein are compositions and methods for use in treating or preventing macular degeneration in a subject. | 06-02-2011 |
20140018305 | ALPHA CONNEXIN C-TERMINAL (ACT) PEPTIDES FOR TREATING AGE-RELATED MACULAR DEGENERATION - Provided herein are compositions and methods for use in treating or preventing macular degeneration in a subject. | 01-16-2014 |
Baerbel Rohrer, Mount Pleasant, SC US
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20080221011 | Targeting complement factor H for treatment of diseases - The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion. | 09-11-2008 |
20110015127 | TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES - The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion. | 01-20-2011 |
20140073572 | TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES - The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion. | 03-13-2014 |
Baerbel Rohrer, Charleston, SC US
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20130137728 | Compositions and Methods for the Treatment of Degenerative Diseases - Disclosed are compounds or pharmaceutically acceptable salts thereof, having the structure of formula I. Also disclosed are methods of preventing and/or treating degenerative disease in a subject, comprising administering to said subject a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions for preventing and/or treating de-generative disease in a subject comprising a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof. | 05-30-2013 |
20140274950 | PYRAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS - Provided herein are compounds of the formula (I): | 09-18-2014 |
20140275075 | ISATIN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS - Provided herein are compounds of the formula (I): | 09-18-2014 |
20140275178 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS - Provided herein are compounds of the formula (I): | 09-18-2014 |
20150057247 | PYRAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS - Provided herein are compounds of the formula (I): | 02-26-2015 |
20150218128 | Isatin Compounds, Compositions And Methods For Treatment Of Degenerative Diseases And Disorders - Provided herein are compounds of the formula (I): | 08-06-2015 |
20160130241 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS - Provided herein are compounds of the formula (I): | 05-12-2016 |
Baerbel M. Rohrer, Charleston, SC US
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20160083469 | TARGETING CONSTRUCTS BASED ON NATURAL ANTIBODIES AND USES THEREOF - The present invention provides targeted delivery methods and constructs for treating inflammatory diseases and/or detecting in vivo tissue injuries in an individual. The targeted delivery approach utilizes an antibody that recognises an epitope found to be present at sites of inflammation. The invention also provides methods of inhibiting complement-driven inflammation in the eye in an individual, comprising administering to the individual an antibody or a fragment thereof or compositions thereof, wherein the antibody or fragment thereof specifically binds to Annexin IV or phospholipid. Also provided are related methods of treating a complement-associated ocular disease or an ocular disease involving oxidative damage. Additionally, the invention provides methods of detecting complement-mediated injury in an eye tissue of an individual, comprising administering to the individual a construct or compositions thereof, wherein the construct comprises (a) an antibody or fragment thereof that specifically binds to Annexin IV or phospholipid; and (b) a detectable moiety. | 03-24-2016 |
Byron Rohrer, San Diego, CA US
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20150309396 | Video Mouthpiece Apparatus and Method of Making Same - A mount and method of manufacturing same is disclosed. The mount includes a mouthpiece for holding the mount in a user's mouth, a video connector piece for mounting a camera to the apparatus, and a connector that structurally secures the mouthpiece and the video connector piece. This provides for a near eye-level point of view while providing hands-free operation. | 10-29-2015 |
Chad Rohrer, Chicago, IL US
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20080234555 | PATIENT CARE SYSTEM - A patient care system includes a support, with a lower portion and an upper portion, and a controller. The upper portion is removably mounted to the lower portion wherein the upper portion may be removed from the lower portion. The lower portion of the support is adapted for being supported on a floor or ground surface. The upper portion is also adapted to mount to a fixture when removed from the lower portion and further includes an input connector for coupling to a monitoring device. The controller is in communication with the input connector, which is adapted for coupling the controller with a monitoring device for receiving data from the monitoring device for one of (1) storing, (2) monitoring, and (3) analyzing the received data. | 09-25-2008 |
20110289691 | PATIENT/INVALID HANDLING SUPPORT - A patient support for a patient includes a mattress with at least one air operated component and a cushioning layer forming a patient support surface. The mattress has a recessed portion beneath the patient support surface at the foot end of the mattress with an enclosure housed in the recess. The enclosure houses therein at least one pump for directing air to the air operated component and a controller for operating the pump. The enclosure has a central section and two side sections, with each of the sections having an upper side. The side sections are located on opposed sides of the central section and at opposed sides of the mattress at the foot end. The upper side of the central section is recessed below the upper sides of the side sections wherein the depth of the cushioning layer at the foot end between the side sections is maintained generally constant at least along the central portion of the mattress extending from the head end to the foot end. | 12-01-2011 |
20150250669 | PATIENT SUPPORT WITH IMPROVED CONTROL - A patient support includes a frame, a patient support surface supported at the frame, a display incorporated into the frame, and a user interface incorporated into the frame. The patient support frame includes a controller incorporated into the frame, which has a plurality of prompts stored therein. The user interface is in communication with the controller and may be used to select a selected prompt from the plurality of prompts stored in the controller. When a prompt is selected, the controller generates a display image or text associated with the selected prompt at the display in response to a passage of time or an input to provide a visual prompt to the user. | 09-10-2015 |
Clay A. Rohrer, Belle, MO US
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20100024446 | REFRIGERATED MERCHANDISER WITH DUAL AIR CURTAIN - A refrigerated merchandiser including a case defining a product display area, and a shelf supported by the case within the product display area. The case includes a base that is disposed below the product display area and a canopy that is disposed substantially above the product display area. The shelf includes an air discharge duct that is configured to direct a first air curtain generally downward from the shelf into the product display area toward the base, and an air return duct that is configured to receive at least a portion of a second air curtain discharged into the product display area from above the shelf. | 02-04-2010 |
Daniel Rohrer, Sata Clara, CA US
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20140295910 | SYSTEM AND METHOD FOR MITIGATING SHOCK FAILURE IN AN ELECTRONIC DEVICE - A roll compensation system for an electronic device, a method of mitigating impact of an electronic device and an impact-resistant mobile device incorporating the system or the method. In one embodiment, the system includes: (1) a plurality of sensors operable to detect orientation and motion of the electronic device, (2) a controller configured to detect a fall based on the motion and determine a mitigating roll based on the orientation and the motion and (3) a compensator operable to carry out the mitigating roll thereby reducing the probability of a catastrophic impact. | 10-02-2014 |
Daniel Rohrer, Los Gatos, CA US
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20110166330 | GPCR crystalization method using an antibody - An antibody that specifically binds a three dimensional epitope on the IC3 loop of a GPCR is provided. The antibody may be employed in a method that comprises: contacting a GPCR with a monovalent version of the antibody binding conditions to form a complex; and crystallizing the complex. | 07-07-2011 |
Daniel F. Rohrer, Powell Butte, OR US
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20110155403 | Portable post driving apparatus - An improved valve for a portable post driver. The post driver has an inner hollow cylinder open at both ends and adapted to receive a post through a lock clamp located at its lower end. An outer hollow cylinder having a closed upper end, and slightly larger in diameter than the inner cylinder, is located in sliding engagement over the inner cylinder. First and second power cylinders are attached to upper and lower surfaces of the outer cylinder in alignment with each other. A common piston rod connects the pistons of the power cylinders. A stationary fastening pin attached to the piston rod extends through a slot in the wall of the outer cylinder and is attached to the wall of the inner cylinder. The valve has a reciprocating valve piston which alternately communicates the two power cylinders to a source of fluid under pressure. | 06-30-2011 |
Daniel K. Rohrer, Los Gatos, CA US
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20090148510 | GPCR crystalization method using an antibody - An antibody that specifically binds a three dimensional epitope on the IC3 loop of a GPCR is provided. The antibody may be employed in a method that comprises: contacting a GPCR with a monovalent version of the antibody binding conditions to form a complex; and crystallizing the complex. | 06-11-2009 |
20120047585 | HCO32 AND HCO27 AND RELATED EXAMPLES - The instant invention relates to transgenic non-human animals capable of producing heterologous antibodies, transgenes used to produce such transgenic animals, transgenes capable of functionally rearranging a heterologous D gene in V-D-J recombination, immortalized B-cells capable of producing heterologous antibodies, methods and transgenes for producing heterologous antibodies of multiple isotypes, methods and transgenes for producing heterologous antibodies wherein a variable region sequence comprises somatic mutation as compared to germline rearranged variable region sequences, transgenic nonhuman animals which produce antibodies having a human primary sequence and which bind to human antigens, hybridomas made from B cells of such transgenic animals, and monoclonal antibodies expressed by such hybridomas. | 02-23-2012 |
David G. Rohrer, Auburn, CA US
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20120262876 | CHASSIS EXTENSION MODULE - A chassis extension module includes an extension housing structure and a support structure. The extension housing structure is to be attached to a housing structure of another module. Attachment of the extension housing structure to the housing structure of the other module expands an inner volume of an assembly. | 10-18-2012 |
20130269997 | ELECTROMAGNETIC INTERFERENCE SHIELDING - A wire defining a repeating pattern is removably joined to a flange having apertures defined therein. The wire includes contact portions to make electrically-conductive contact with a device supported by a chassis. The device can be cooled by air flow through the apertures of the flange while being protected against electromagnetic interference (EMI). The wire and the flange can be respectively formed from various metals and are separable from each other for recycling or other purposes. | 10-17-2013 |
20130279501 | BACKPLANE MODULE - Modules, modular devices, and modular systems are provided. Some examples include a backplane oriented in a first plane, a first module including a major surface oriented parallel to the first plane and a first minor surface oriented perpendicular to the first plane, wherein the major surface of the first module includes a connector thereon that releasably mates with a corresponding connector located on a first side of the backplane. Some examples include a second module including a major surface oriented perpendicular to the first plane and a first minor surface oriented parallel to the first plane, wherein the first minor surface of the second module includes a connector thereon that releasably mates with a corresponding connector located on a second side of the backplane. Circuitry within the first module can provide interconnections for the second module. The first and second modules can be fabric and interface modules, respectively. | 10-24-2013 |
20130284682 | CHASSIS CARD CAGE - A chassis card cage includes a front panel, a backplane opposite the front panel, opposing sides extending between the front panel and the backplane, a series of module slots extending between opposing sides, each of the series of module slots configured to accommodate a card module, and a module slot divider including a first portion extending perpendicularly from the backplane and a second portion connectable to the first portion and extending from the second portion toward the front panel, wherein at least the second portion of the module slot divider has a divider height substantially equal to a height of a single module slot and is configured to divide one of the series of module slots into side-by-side module slots. | 10-31-2013 |
20130293075 | CHASSIS APPARATUS PROTRUDING ELECTRONIC DEVICES - An apparatus includes a chassis including at least one receiving buttress. The chassis defines an enclosure, and the at least one buttress protrudes a portion electronic devices outside the enclosure by preventing further insertion of the electronic devices into the enclosure. | 11-07-2013 |
20140036451 | HEAT SINK ASSEMBLY - A heat sink assembly includes a printed circuit board, a heat sink, and clamp, and at least two clamp retainers. The printed circuit board has at least two holes extending from a front surface to a back surface of the printed circuit board. The heat sink is mounted to the printed circuit board. The heat sink has a bottom side and a plurality of fins extending from a top side. The clamp is coupled to the printed circuit board. The clamp includes a beam extending across the heat sink and between adjacent fins, at least two legs extending through the at least two holes of the printed circuit board, and a foot extending from each of the at least two legs contacting the back surface of the printed circuit board. The at least two clamp retainers extend through the at least two holes adjacent to the at least two legs. | 02-06-2014 |
David G. Rohrer, Roseville, CA US
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20130074697 | FILTER FOR ELECTRICAL EQUIPMENT - An air filter for electrical equipment includes metallic filter media including a first outer layer, an opposing second outer layer, and at least one inner layer disposed between the first outer layer and the opposing second outer layer, and a frame disposed along a perimeter edge of the filter media configured to retain the filter media. | 03-28-2013 |
Ellen Rohrer, Katonah, NY US
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20140212565 | Nutrition Beverages - Nutrition beverage compositions including high concentrations of protein are provided. Methods of making nutrition beverage compositions including high concentrations of protein are provided. | 07-31-2014 |
Gerald E. Rohrer, Cochranville, PA US
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20150327443 | Apparatus for Converting Large Bales of Forage Material into Small Rectangular Bales of Forage Material - An apparatus for disintegrating large rectangular bales of forage or bedding material and reforming the disintegrated material into small rectangular bales includes an inclined conveyor having spikes projecting therefrom to remove slices of material from the large bale and a spiked roller to move the slice rearwardly onto a tumbler bed that receives the slice and affects disintegration thereof. The tumbler bed includes a plurality of transverse assemblies having disks interleaving with the disks on adjacent assemblies, each assembly rotating faster than the assembly immediately forwardly thereof. The disintegrated material falls through the tumbler bed as discrete components that land on a collecting conveyor that conveys the material rearwardly to a small rectangular baler for repackaging. The apparatus further includes a hold-down mechanism that presses the slices toward the tumbler bed to enhance disintegration. An approach conveyor feeds the large rectangular bales loaded thereon to the inclined conveyor for processing. | 11-19-2015 |
James H. Rohrer, Randolph, NJ US
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20120222317 | CUTTER BLADE HEAD FOR FIBER ROVING CHOPPER - A blade cartridge for a fiber roving chopper comprises an annular support and a plurality of blade holders. Each of the plurality of blade holders comprises a main body portion, a first end, a second end, and a blade. The first end of the main body portion is connected to the annular support. The second end of the main body portion is opposite the first end such that the main body portion is cantilevered from the annular support. The blade is integrally seated in the main body portion and extends between the first end and the second end. In a further embodiment of the invention, the main body portion of the blade holder includes first and second end notches that extend through the main body portion and the blade. | 09-06-2012 |
20120227559 | ANVIL FOR FIBER ROVING CHOPPER - An anvil assembly for a fiber roving chopper comprises an annular roller and an annular anvil wheel. The annular roller comprises an inner diameter surface with a plurality of dovetails, and an outer diameter surface comprising a deformable material. The annular anvil wheel comprises an inner diameter surface forming a central bore for mounting the anvil assembly in the fiber roving chopper, and an outer diameter surface extending between a first end and a second end and having a plurality of dovetail slots that receive the plurality of dovetails. | 09-13-2012 |
James M. Rohrer, Burlington, WI US
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20130064884 | COMPOSITION AND METHOD FOR TREATING KETOSIS IN COWS - A method for prophylactic treatment of ketosis in a calving cow, the method including orally administering to the cow within a time period of about 12 hours after calving an effective dose of from 20 to 30 g of rumen protected methionine. If the cow falls into a risk category, the cow is administered the dose of rumen protected methionine once a day on the second, third, fourth, and fifth days after calving. Also, a composition including a gelatin capsule and rumen-protected methionine contained within the gelatin capsule that may be administered to a calving cow for the prophylactic treatment of ketosis. The composition may further contain within the gelatin capsule one or more other compounds known to have efficacy on fat or glucose metabolism, such as glucose, propylene glycol, niacin, choline, chromium, calcium propionate, and glucocorticoids. | 03-14-2013 |
James W. Rohrer, Mobile, AL US
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20130052211 | VACCINES WITH ONCOFETAL ANTIGEN/ILRP-LOADED AUTOLOGOUS DENDRITIC CELLS AND USES THEREOF - Disclosed are compositions containing isolated monocyte-derived mature dendritic cells loaded with OFA/iLRP, or a fragment thereof that selectively stimulates T cytotoxic lymphocytes, and a carrier, vaccine compositions containing effective dosage amounts of the dendritic cells, methods of making the vaccines, and methods of cancer treatment or therapy that entail administration of the vaccines to cancer patients. | 02-28-2013 |
20150218287 | TUMOR SELECTIVE ANTIBODIES SPECIFIC TO ONCOFETAL ANTIGEN/IMMATURE LAMININ RECEPTOR PROTEIN - Disclosed are high affinity antibodies or antigen-binding fragments thereof, which bind an epitope that lies within the C-terminal region of oncofetal antigen (OFA)/immature laminin receptor protein (iLRP), and which do not substantially cross-react with mature OFA/LRP. The antibodies may be conjugated to cytotoxic moieties to enhance their therapeutic efficacy. Methods of making the antibodies and therapeutic and diagnostic uses thereof are also disclosed. | 08-06-2015 |
James W. Rohrer, Wilmer, AL US
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20100183643 | Cancer vaccines containing epitopes of oncofetal antigen - Disclosed are fragments of oncofetal antigen, otherwise known as immature laminin receptor protein that specifically stimulate one T cell subclass. The fragments may be formulated into compositions for potentiating T cell-mediated responses in mammalian cancer patients. They also have therapeutic uses in vitro. | 07-22-2010 |
Jason M. Rohrer, Reading, PA US
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20160137119 | Apparatus for Deploying and Retrieving Highway Panels - An apparatus facilitates the deployment and retrieval of highway panels and includes a work basket mountable on the rearward end of a truck to be vertically moveable relative thereto. A ramp member is detachably mounted on a selected side of the work basket to be movable therewith. A lift member is detachably mounted on a four-bar lift linkage carried by the truck along the selected side thereof. The lift member is vertically movable by the lift linkage to raise the highway panels from the ramp member to the level of the truck bed on which the highway panels are transported. Both the ramp and lift members are formed with rollers on the top surface to facilitate the movement of the highway panels in both deployment and retrieval. Retrieval is accomplished by moving the truck rearwardly and tipping the highway panel so the ramp member can slide underneath the base. | 05-19-2016 |
John Rohrer, York, ME US
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20130113211 | Submergable sloped absorption barrier wave energy converter - An ocean wave energy converter uses one or more buoyant elongated float(s) self orienting toward oncoming wave fronts and movably affixed to a motion stabilized controlled buoyancy frame by down sloping tracks constraining the wave induced motion of the float(s) to an upward and rearward motion as oncoming wave crests impact and lift the barrier(s) and downward and forward as subsequent wave troughs return it. Motion between the barrier(s) and the frame is resisted and energy captured by a programmable electric or hydraulic power take off system. Capture efficiency is further enhanced by adjusting float mass and buoyancy by controlling water entering or exiting cavities in the float(s), use of wave shoaling and focusing means, and adjusting the submerged depth and slope angle of the device with adjustable frame air-water ballast tanks which also allow total float submergence during severe sea states. | 05-09-2013 |
John W. Rohrer, York, ME US
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20100308589 | Heaving ocean wave energy converter - An ocean wave energy device uses large gas filled and surface vented or evacuated flexible containers having rigid movable ends and rigid fixed depth ends connected by flexible bellows, suitably reinforced against external hydrostatic pressure, submerged to a depth below anticipated wave troughs. One or more containers compress and expand as waves and troughs, respectively, pass overhead driving hydraulic or pneumatic, pumping means producing pressurized fluid flow for a common sea bed motor-generator or for other uses or on-board direct drive generators. Mechanical, hydraulic or pneumatic means re-expand said containers when a wave trough is overhead. Power output is augmented by mechanically connecting said rigid moving surfaces to surface floats, which may also provide said surface vent such that as waves lift and troughs lower said floats, said containers are further compressed and re-expanded, respectively. Depth fixing and adjustment means for tides and sea-states are provided. | 12-09-2010 |
20100308590 | Ocean wave energy converter capturing heave, surge and pitch motion - An ocean wave energy device uses large gas filled and surface vented or partially evacuated flexible containers each having rigid movable ends and rigid fixed depth ends connected by flexible bellows, suitably reinforced against external hydrostatic pressure, submerged to a depth below anticipated wave troughs. One or more said containers compress and expand as waves and troughs, respectively, pass overhead driving hydraulic or pneumatic, pumping means producing pressurized fluid flow for a common sea bed motor-generator or for other uses or on-board direct drive generators. Mechanical, hydraulic or pneumatic means re-expand said containers when a wave trough is overhead. Power output is augmented by mechanically connecting said rigid moving surfaces to surface floats, which may also provide said submerged container venting such that as waves lift and troughs lower said floats, said containers are further compressed and re-expanded, respectively. Power output is further augmented by wave kinetic energy capture through focusing, reflection and refraction. | 12-09-2010 |
20120032446 | Ocean wave energy converter with multiple capture modes - An ocean wave energy converter utilizes a substantially submerged elongated absorption barrier oriented parallel to oncoming wave fronts having one or more substantially submerged air or gas filled variable volume vessels located between a relatively fixed position rigid rearward surface and a moving rigid wave front facing surface. Said vessel(s) are compressed by oncoming overhead wave crests both by increased hydrostatic pressure and wave kinetic impact, thereby capturing both wave potential energy (hydrostatic or heave) and kinetic (impact or surge) energy. Vessel compression is resisted by hydraulic, pneumatic, mechanical or linear electric generation means. Vessel re-expansion, when wave troughs are overhead, utilize hydraulic, pneumatic, electric, and/or mechanical (gravity mass or spring) means. Wave energy capture is enhanced by venting vessel air or gas directly to and from atmosphere or low pressure surface expandable vessel(s), which venting may also drive pneumatic turbine-generators, and by oncoming wave shoaling and focusing means. | 02-09-2012 |
20140097617 | Multi-Capture Mode Wave Energy Converter With Submergible Float - An ocean wave energy converter (WEC) uses one or more buoyant elongated float(s) mechanically linked to a motion-stabilized, controlled-submergence depth frame by either swing or lever arms or down-sloping tracks defining and orienting the motion of the floats relative to the frame to capture both heave and surge wave energy forces. The submerged depth of the frame and attached float(s) is adjusted for optimal wave energy capture or submerged sufficiently to fully submerge the float(s) during severe sea conditions. The elongated float's compliant wave-impacting forward wall combined with total submergence during severe sea states allows the elongated float(s) to self-orient parallel to oncoming wave fronts to intercept and capture maximum wave energy per unit of WEC volume, weight and cost. | 04-10-2014 |
20150082785 | Wave Energy Converter With Concurrent Multi-Directional Energy Absorption - An ocean wave energy converter (WEC) using one or more elongated light-weight low-cost surface floats, oriented and self-orienting parallel to oncoming wave fronts are mechanically linked to a motion stabilized or fixed frame or base through one or more power take-offs in such manner that multi-directional rotational and translational wave-induced forces and relative motion between the float(s) and base are efficiently captured. Some embodiments have at least one forward positioned float that moves upward and rearward on wave crests and downward and forward on ensuing wave troughs to capture a majority of both heave and surge wave energy components. Other embodiments also provide apparatus and means to totally submerge the floats during severe seas or adjust submerged depth and float mass to optimize performance. | 03-26-2015 |
Mark Rohrer, Blaine, MN US
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20140046397 | APPARATUS FOR TREATING PELVIC FLOOR DISORDERS AND RELATED METHODS OF USE - A method of optimizing the electrical stimulation of a bladder of a patient including selecting a first subset of electrodes from a set of electrodes positioned adjacent to a set of nerves associated with the bladder. The set of electrodes may include one or more electrodes, each of which may be configured to deliver electrical stimulation pulses generated by a stimulator device to the nerves. The method may further include delivering an electrical stimulation pulse through the selected first subset of electrodes and recording at least one parameter of the electrical stimulation pulse after receiving patient feedback. | 02-13-2014 |
20150025594 | APPARATUS FOR TREATING PELVIC FLOOR DISORDERS AND RELATED METHODS OF USE - A method of optimizing the electrical stimulation of a bladder of a patient including selecting a first subset of electrodes from a set of electrodes positioned adjacent to a set of nerves associated with the bladder. The set of electrodes may include one or more electrodes, each of which may be configured to deliver electrical stimulation pulses generated by a stimulator device to the nerves. The method may further include delivering an electrical stimulation pulse through the selected first subset of electrodes and recording at least one parameter of the electrical stimulation pulse after receiving patient feedback. | 01-22-2015 |
20160045729 | APPARATUS FOR TREATING PELVIC FLOOR DISORDERS AND RELATED METHODS OF USE - A method of optimizing the electrical stimulation of a bladder of a patient including selecting a first subset of electrodes from a set of electrodes positioned adjacent to a set of nerves associated with the bladder. The set of electrodes may include one or more electrodes, each of which may be configured to deliver electrical stimulation pulses generated by a stimulator device to the nerves. The method may further include delivering an electrical stimulation pulse through the selected first subset of electrodes and recording at least one parameter of the electrical stimulation pulse after receiving patient feedback. | 02-18-2016 |
Michael Rohrer, Cedar Park, TX US
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20160071686 | LINKAGE CONDUIT FOR VACUUM CHAMBER APPLICATIONS - An ion implantation apparatus including an enclosure defining a process chamber, a carriage slidably mounted on a shaft within the process chamber and coupled to a drive mechanism adapted to selectively move the carriage along the shaft. A platen assembly can be coupled to the carriage, and a linkage conduit can extend between a side wall of the enclosure and the carriage. The linkage conduit can include a plurality of pivotably interconnected linkage members that define a contiguous internal volume that is sealed from the process chamber. The contiguous volume can be held at a desired vacuum pressure separate from the vacuum environment of the process chamber. | 03-10-2016 |
Michelle Rohrer, San Carlos, CA US
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20110173708 | NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO - The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO226, PRO257, PRO268, PRO290, PRO36006, PRO363, PRO365, PRO382, PRO444, PRO705, PRO1071, PRO1125, PRO1134, PRO1155, PRO1281, PRO1343, PRO1379, PRO1380, PRO1387, PRO1419, PRO1433, PRO1474, PRO1550, PRO1571, PRO1572, PRO1759, PRO1904, PRO35193, PRO4341, PRO4348, PRO4369, PRO4381, PRO4407, PRO4425, PRO4985, PRO4989, PRO5737, PRO5800, PRO5993, PRO6017, PRO7174, PRO9744, PRO9821, PRO9852, PRO9873, PRO10196, PRO34778, PRO20233, PRO21956, PRO57290, PRO38465, PRO38683 or PRO85161 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. | 07-14-2011 |
20120272341 | NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO - The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO226, PRO257, PRO268, PRO290, PRO36006, PRO363, PRO365, PRO382, PRO444, PRO705, PRO1071, PRO1125, PRO1134, PRO1155, PRO1281, PRO1343, PRO1379, PRO1380, PRO1387, PRO1419, PRO1433, PRO1474, PRO1550, PRO1571, PRO1572, PRO1759, PRO1904, PRO35193, PRO4341, PRO4348, PRO4369, PRO4381, PRO4407, PRO4425, PRO4985, PRO4989, PRO5737, PRO5800, PRO5993, PRO6017, PRO7174, PRO9744, PRO9821, PRO9852, PRO9873, PRO10196, PRO34778, PRO20233, PRO21956, PRO57290, PRO38465, PRO38683 or PRO85161 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. | 10-25-2012 |
Norman J. Rohrer, San Jose, CA US
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20120066657 | METHOD OF DESIGNING AN INTEGRATED CIRCUIT BASED ON A COMBINATION OF MANUFACTURABILITY, TEST COVERAGE AND, OPTIONALLY, DIAGNOSTIC COVERAGE - Disclose are embodiments of an integrated circuit design method based on a combination of manufacturability, test coverage and, optionally, diagnostic coverage. Design-for manufacturability (DFM) modifications to the layout of an integrated circuit can be made in light of test coverage. Alternatively, test coverage of an integrated circuit can be established in light of DFM modifications. Alternatively, an iterative process can be performed, where DFM modifications to the layout of an integrated circuit are made in light of test coverage and then test coverage is altered in light of the DFM modifications. Alternatively, DFM modifications to the layout of an integrated circuit can be made in light of test coverage and also diagnostic coverage. In any case, after making DFM modifications and establishing test coverage, any unmodified and untested nodes (and, optionally, any unmodified and undiagnosable tested nodes) in the integrated circuit can be identified and tagged for subsequent in-line inspection. | 03-15-2012 |
20140281601 | POWER BOUNDARY CELL OPERATION IN MULTIPLE POWER DOMAIN INTEGRATED CIRCUITS - Embodiments of an apparatus are disclosed that may allow for the isolation of power domains. The apparatus may include a first power switch, a second power switch, and a boundary switch. The first power switch may be coupled between a global power supply and a first local power supply, and the second power switch may be coupled between the global power supply and a second local power supply. The first and second power switches may open in response to first and second power down signals respectively. The boundary switch may be coupled between the first local power supply and the second local power supply and may be configured to open in response to an isolation signal. | 09-18-2014 |
Norman Jay Rohrer, Underhill, VT US
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20090108863 | METHOD AND CIRCUIT FOR DETECTING AND COMPENSATING FOR A DEGRADATION OF A SEMICONDUCTOR DEVICE - A design structure and method comprising a degradation detection circuit configured to respond to degradation. The degradation detection circuit is located within a semiconductor device and comprises a process sensitive circuit, a measurement circuit, a calculation circuit, and a control circuit. The method comprises subjecting the semiconductor device to a first operating condition. A first value at a first time for a parameter of the process sensitive circuit is measured by the measurement circuit. The semiconductor device is operated to perform an intended function. A second value at a second time for the parameter of the circuit is measured by the measurement circuit. The second time is different from the first time. A first differential value between the first value and the second value is determined by the calculation circuit. The control circuit is configured to receive an enable signal. | 04-30-2009 |
20090108868 | METHOD AND CIRCUIT FOR MATCHING SEMICONDUCTOR DEVICE BEHAVIOR - A design structure and method. The design structure comprises a selection circuit comprising a logic circuit, an array of sub-circuits and a switching circuit electrically coupled to each other. The selection circuit is subjected to a first operating condition. The switching circuit selects a group of sub-circuits from the array. The selection circuit generates a first frequency. The selection circuit is subjected to a second operating condition that is different from the first operating condition and generates a second frequency. A first frequency differential between the first frequency and the second frequency is compared to a predetermined frequency differential to determine if the first frequency differential is about equal to the predetermined frequency differential. | 04-30-2009 |
Sandra Lee Rohrer, Mesa, AZ US
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20090049755 | STEPPED FRAMES FOR STEEL CLOSURES - A structural steel stepped closure frame is disclosed having a closure stop that is spaced apart from the closure jamb and discontinuously joined thereto, forming gaps between the closure jamb and the closure stop. The gaps and joinery are obscured from frontal view by a stop face positioned forward of the closure stop, creating a partially hidden closure stop. The partially hidden closure stop may extend entirely around the closure for windows or lids, or less than entirely for doors or gates. The gaps receive legs of a weather stripping that has a flange extending over the closure stop. The partially hidden closure stop, along with the jamb, extensions, and facings, are sized, shaped, and arranged to create a stepped appearance. | 02-26-2009 |
Stuart Rohrer, New York, NY US
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20090016504 | System and Method for Providing Communications to a Group of Recipients Across Multiple Communication Platform Types - A communications system for enabling communications between a prime user and members of a group. The system includes a first set of interlaces capable of communicating with the prime user via a first plurality of communication platforms using at least a first format and a second format; and a second set of interfaces capable of communicating with each of the members of the group via a second plurality of communication platforms using at least the first format and the second format. The system also includes a session manager coupled to the first set of interfaces having a plurality of routines configured to enable a prime user in communication with any one of the first set of interfaces to create a message to be transmitted to a selected group in either the first format or the second format; and a format converter capable of converting the message between the first and second formats. A communication controller is configured to obtain the message from the first database in both the first and second formats, obtain group member information regarding each member's contact preferences, and to initiate transmission of the message from the second set of interfaces to the selected group members using various, communication platforms based on the member's contact preferences. | 01-15-2009 |
Suzanne Rohrer, Mobile, AL US
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20130052211 | VACCINES WITH ONCOFETAL ANTIGEN/ILRP-LOADED AUTOLOGOUS DENDRITIC CELLS AND USES THEREOF - Disclosed are compositions containing isolated monocyte-derived mature dendritic cells loaded with OFA/iLRP, or a fragment thereof that selectively stimulates T cytotoxic lymphocytes, and a carrier, vaccine compositions containing effective dosage amounts of the dendritic cells, methods of making the vaccines, and methods of cancer treatment or therapy that entail administration of the vaccines to cancer patients. | 02-28-2013 |
Tami J. Rohrer, Charlotte, NC US
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20150235324 | DETECTING SUSPICIOUS ACTIVITY RELATED TO BALANCING TRANSACTIONS AT A CASH DRAWER - Systems, apparatus, methods, and computer program products are provided for automatically monitoring cash balancing transactions conducted by individuals responsible for a cash drawer to determine unique behaviors/patterns of such individuals that are abnormal to the overall population of cash drawer users. Such proactive monitoring of cash balancing transactions provides for suspicious activity to be identified at the onset of such activity. As such, the identified suspicious activity can be further investigated to determine the cause of the activity. Thus, by identifying the suspicious activity at an earlier stage, financial losses to the financial institution can be reduced and reputational risk can be minimized. | 08-20-2015 |
Thomas L. Rohrer, San Anselmo, CA US
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20110088003 | APPARATUS, METHODS AND COMPUTER-READABLE STORAGE MEDIA FOR SECURITY PROVISIONING AT A COMMUNICATION DEVICE - Apparatus, methods and computer-readable storage medium are provided for security provisioning at a communication device. In some embodiments, a method can include: executing a high security application on a communication device based, at least, on detecting that high security is enabled for the communication device and detecting execution of a low security application; outputting, via a user interface (UI), information configured to detect an entry to the communication device; detecting an entry at the UI of the communication device; determining whether the entry corresponds to security access information stored in the communication device; and providing access to the communication device based, at least, on determining that the entry corresponds to the security access information. | 04-14-2011 |
20150356323 | APPARATUS, METHODS AND COMPUTER-READABLE STORAGE MEDIA FOR SECURITY PROVISIONING AT A COMMUNICATION DEVICE - Apparatus, methods and computer-readable storage medium are provided for security provisioning at a communication device. In some embodiments, a method can include: executing a high security application on a communication device based, at least, on detecting that high security is enabled for the communication device and detecting execution of a low security application; outputting, via a user interface (UI), information configured to detect an entry to the communication device; detecting an entry at the UI of the communication device; determining whether the entry corresponds to security access information stored in the communication device; and providing access to the communication device based, at least, on determining that the entry corresponds to the security access information. | 12-10-2015 |
Tim Rohrer, Bend, OR US
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20150305314 | Compact Portable Fishing Pole - A portable fishing device is provided having a handle with a spool providing a line reel rotationally engaged at one end which is sized for placement in a clothing pocket when not being employed. The handle has a gripping area adjacent one side of the spool and a lanyard having a loop positionable around the arm or wrist of a user gripping the handle in the gripping area to tether the fishing device to the user. The fishing device has only one moving part, that being the spool on the handle, to minimize potential loss of use from mechanical failure. | 10-29-2015 |
Timothy Rohrer, Pittsford, NY US
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20160018316 | INSPECTION WINDOW - An apparatus comprises an optical pane transparent to infrared radiation. The pane includes first and second sides, a periphery, and a retention region. A frame defines an opening that can accept the pane and includes a pane retention region. Additionally, a retainer is configured to secure the optical pane in the opening and includes a retaining surface mated to the pane support surface of the frame and configured to support the optical pane at the retention region. The pane, frame and retainer are configured to have mating features which can include a bead, a retaining ridge, a labyrinth configuration and protrusions, recesses, channels, or steps or a combination of these features. | 01-21-2016 |
Timothy L. Rohrer, Jacksonville, FL US
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20150366001 | SYSTEM AND METHOD FOR MACHINE PARAMETER ANALYSIS IN WIRELESS FIELD UNITS - A sensor sampling system comprises a field unit to receive at least one analysis parameter from a base station and a signal representing a machine parameter monitored by a machine sensor. The field unit analyzes the signal based on the at least one machine parameter to generate a representation of the machine parameter, and wirelessly transmits the representation of the machine parameter for reception by the base station. | 12-17-2015 |