Roepman
Paul Roepman, Utrecht NL
Patent application number | Description | Published |
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20100184052 | PROGNOSTIC GENE EXPRESSION SIGNATURE FOR NON SMALL CELL LUNG CANCER PATIENTS - The invention relates to a method of typing non-small cell lung cancer cells by determining RNA levels for a set of genes. Said typing can be used for determining a metastasizing potential of the cancer cells. The invention further relates to a set of probes and a set of primers that can be used for typing non-small cell lung cancer cells. | 07-22-2010 |
20110269127 | MEANS AND METHOD FOR DETERMINING TUMOR CELL PERCENTAGE IN A SAMPLE - The invention provides a method for determining the percentage of tumor cells in a sample of an individual, preferably a breast sample. More specifically, the invention provides one or more genes than can be used to determine the percentage of tumor cells. The invention further provides a set of probes, a set of primers, and uses thereof for detection of said one or more genes. | 11-03-2011 |
20110319285 | METHODS AND MEANS FOR TYPING A SAMPLE COMPRISING COLORECTAL CANCER CELLS - The invention relates to a method of typing colorectal cancer cells by determining the RNA levels of a set of signature genes. Said typing can be use for predicting a risk for recurrence of said colorectal cancer. The invention further relates to a set of genes that can be used for normalizing the RNA levels of said set of signature genes, and to micro-array comprising said set of signature genes. | 12-29-2011 |
Paul Roepman, Wageningen NL
Patent application number | Description | Published |
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20090005258 | Diagnosis of Metastases in Hnscc Tumours - The invention relates to the detection or prediction of metastases of head and neck squamous cell carcinoma (HNSCC) with the use of gene expression profiles. A gene signature has been identified which is able to detect or predict the occurrence of these metastases better than current clinical methods. Part of the invention are micro-arrays comprising this signature and methods for performing the detection and/or prediction. | 01-01-2009 |
Paul Roepman, Bilthoven NL
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20130178381 | MEANS AND METHODS FOR MOLECULAR CLASSIFICATION OF BREAST CANCER - The invention relates to a method of typing a sample from a breast cancer patient. More specifically, the invention relates to a method for classification of breast cancer according to the presence or absence of Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal growth factor Receptor 2 (ERBB2; HER2). More specifically, the invention provides methods and means to classify breast cancer as ER positive, triple negative (ER | 07-11-2013 |
20130302321 | Methods and Means for Typing a Sample Comprising Cancer Cells Based on Oncogenic Signal Transduction Pathways - The invention is related to a method of determining whether an individual suffering from cancer is likely to respond to anti-EGFR and/or EGFR pathway therapy. In one aspect, the invention utilizes the expression level of a set of genes for determining said response. In a further aspect, the invention relates to a method of assigning treatment to an individual suffering from cancer. | 11-14-2013 |
Paul Roepman, Amsterdam NL
Patent application number | Description | Published |
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20130296191 | Methods and Means for Molecular Classification of Colorectal Cancers - The invention relates to methods of typing a sample from a colorectal cancer patient based on the levels of RNA expression products in a cancer cell of the patient. The invention further relates to methods for determining a strategy for treatment of a patient suffering from colorectal cancer, and to methods for assigning treatment to a patient suffering from colorectal cancer. | 11-07-2013 |