Patent application number | Description | Published |
20080255370 | SINGLE CARBON PRECURSOR SYNTHONS - The chemistry of [ | 10-16-2008 |
20080255384 | THREE CARBON PRECURSOR SYNTHONS | 10-16-2008 |
20080269527 | ISOTOPICALLY TAGGED SYNONS FROM 2 CARBON PRECURSORS - The use of vinyl sulfides, sulfoxides and sulfones in synthetic chemistry for the production of a wide variety of materials is well known. For example, phenyl vinyl sulfides, sulfoxides and sulfones have been used for the synthesis of important heterocycles, in combinatorial chemistry and as Diels-Alder adducts. Although these compounds have been used extensively for a variety of applications, the isotopically labeled versions have not been reported. A simple route for the isotopically labeled production of these important building blocks has been developed. | 10-30-2008 |
20090030232 | Synthesis of [1-13C]pyruvic acid], [2-13C]pyruvic acid], [3-13C]pyruvic acid] and combinations thereof - The present invention is directed to the labeled compounds, | 01-29-2009 |
20090259064 | SYNTHESIS OF PHOSPHONIC ACID LABELED COMPOUNDS - High purity isotopically labeled phosphonic acid esters can be obtained from isotopically enriched Chloro[ | 10-15-2009 |
20100069675 | SYNTHESIS OF [1-13C]PYRUVIC ACID], [2-13C]PYRUVIC ACID], [3-13C]PYRUVIC ACID] AND COMBINATIONS THEREOF - The present invention is directed to the labeled compounds, | 03-18-2010 |
20100317886 | SYNTHESIS OF ISOTOPICALLY-LABELED FUNCTIONALIZED DIENES - All labeled carbons are derived ultimately from CO, as carbon-13 is separated from its lighter isotope by cyrogenic distillation of carbon monoxide (CO). Creation of stereospecific and site-specific compounds used for starting materials will address growing demands for labeled compounds, including isotopically-labeled functionalized dienes. Functionalized diene compounds can be used as precursors for the production of isotopically labeled pharmaceuticals, biomolecules, and natural products. | 12-16-2010 |
20110010878 | HYDRAZINE DECONTAMINATION WIPES - An apparatus for remediating hydrazine from hydrazine contaminated surfaces. Pads or wipes can be utilized to remediate hydrazine spills. In its operational form, the dicarbonyl compound may be present on or in the absorbent material in a dry form or an aqueous solution. The apparatus includes a wipe comprising an absorbent medium pre-treated with a dicarbonyl compound, wherein the surface contaminated with hydrazine reacts with the dicarbonyl compound of the wipe to neutralize and convert the hydrazine into a stable organic compound, thereby decontaminating the surface. The wipe itself may include a porous surface cover surrounding an inert absorbent interior component of the wipe that in turn surrounds an absorbent interior core comprising a dicarbonyl compound that reacts with the hydrazine in order to neutralize the hydrazine on the surface. The absorbent medium generally comprises a porous outer fabric surface covering that draws the hydrazine on the surface to the wipe. | 01-20-2011 |
20110011266 | AIR FILTRATION AND ABSORPTION METHOD AND SYSTEM FOR THE REMEDIATION OF HYDRAZINE - An air filtration system and method for the remediation of hydrazine from contaminated air. The system is provided in the form of a container with an inlet port and an outlet port containing absorbent pads or filters or wipes saturated with a solution of a dicarbonyl compound. As contaminated air passes through the container, hydrazine present within the air reacts with the dicarbonyl compound and becomes neutralized, thereby resulting in the exit of pure air from the container. The absorbent pads can also be used independently to remove hydrazine liquid spill. | 01-20-2011 |
20110182780 | HYDRAZINE FILTRATION METHOD AND SYSTEM - A filtration system and method for the remediation of hydrazine from contaminated gas is disclosed. The system is provided in the form of a container with an net port and an outlet port containing absorbent pads or filters or wipes saturated with a solution of a dicarbonyl compound. As contaminated gas passes through the container, hydrazine present within the gas reacts with the dicarbonyl compound and becomes neutralized, thereby resulting in the exit of pure gas that no longer contains hydrazine from the container. The system can remediate hydrazine from ammonia borane to efficiently regenerate spent said ammonia borane from polyborazylene as a hydrogen storage material. The absorbent pads can also be used independently to remove hydrazine liquid spill. | 07-28-2011 |
20110194988 | HYDRAZINE SPILL PAD APPARATUS AND METHOD OF MANUFACTURING - An apparatus for remediating hydrazine and a method of manufacturing the apparatus for remediating hydrazine are disclosed. A pad treated with a dicarbonyl compound can be utilized to remediate hydrazine spills or hydrazine-contaminated surfaces. The apparatus to remediate hydrazine includes a pad comprising an absorbent medium pre-treated with a dicarbonyl compound, wherein a solution, surface, device, or component contaminated with hydrazine reacts with the dicarbonyl compound of the pad to convert the hydrazine into a stable organic compound, thereby decontaminating the spill. The pad may include a porous surface cover surrounding an inert absorbent medium component that in turn supports a dicarbonyl compound that reacts with the hydrazine from the surface. The absorbent medium can be a pad, fibrous material, granular material, or an aqueous absorbent medium. The absorbent medium generally comprises a porous outer fabric surface covering that allows solutions or vapors to pass into the pad's interior. | 08-11-2011 |
20140275624 | PREPARATION OF 4-AMINO-2,4-DIOXOBUTANOIC ACID - A process for synthesizing 4-amino-2,4-dioxobutanoic acid involves reacting diethyl oxalate with sodium ethoxide in ethanol to form a reaction mixture, and afterward adding 2-cyano-3-hydroxy-butenedioate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl-2-cyano-3-hydroxy-butenedioate, and then isolating the cyano-3-hydroxy-butenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with aqueous sodium hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoic acid. | 09-18-2014 |
20150065750 | Preparation of 4-Amino-2,4-Dioxobutanoic Acid - A process for synthesizing 4-amino-2,4-dioxobutanoic acid involves reacting diethyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding ethyl cyanoacetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl 2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl 2-cyano-3-hydroxy-butenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoic acid. | 03-05-2015 |
20150065751 | Preparation of 4-Amino-2,4-Dioxobutanoic Acid - A first process for synthesizing 4-amino-2,4-dioxobutanoate involves reacting a dialkyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding an alkyl cyanoacetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl 2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl 2-cyano-3-hydroxy-butenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoate. A second process for synthesizing 4-amino-2,4-dioxobutanoate involves reacting a dialkyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding acetonitrile to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product in the form of an alkali salt of the formula ethyl 3-cyano-2-oxopropenolate, and then isolating the ethyl 3-cyano-2-oxopropenolate , and afterward either (a) reacting the ethyl 3-cyano-2-oxopropenolate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoate; or (b) reacting the ethyl 3-cyano-2-oxopropenolate with hydrogen peroxide and ion exchange resin under conditions suitable to form 4-amino-2,4-dioxobutanoate. In these processes, the 4-amino-2,4-dioxobutanoate may be acidified into 4-amino-2,4-dioxobutanoic acid. | 03-05-2015 |