Patent application number | Description | Published |
20080249464 | Catheter Having Internal Mechanisms to Encourage Balloon Re-folding - A balloon catheter that comprises an inner shaft, a balloon and a sleeve that defines a lumen. A portion of the inner shaft is positioned within the lumen and the balloon is engaged to the sleeve at least two engagement points. | 10-09-2008 |
20080262412 | Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power - The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents. | 10-23-2008 |
20090294732 | COATINGS FOR MEDICAL DEVICES HAVING REVERSIBLE HYDROPHOBIC TO HYDROPHILIC PROPERTIES - A medical device including a coating disposed on at least a portion of a surface of the medical device, the coating including at least one polymer material having reversible wettability. | 12-03-2009 |
20100241071 | Polymeric/Inorganic Composite Materials for Use in Medical Devices - In one aspect, the present invention provides composite coatings for implantable or insertable medical devices. These composite coatings comprise (a) an inorganic portion and (b) a polymeric portion that comprises a poly(vinyl pyrrolidone) (PVP) block. | 09-23-2010 |
20110046539 | INTERNAL MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENT IN CONJUNCTION WITH A SOURCE OF ELECTRICAL POWER - The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents. | 02-24-2011 |
20110152912 | Catheter Having Internal Mechanisms to Encourage Balloon Re-folding - A balloon catheter that comprises an inner shaft, a balloon and a sleeve that defines a lumen. A portion of the inner shaft is positioned within the lumen and the balloon is engaged to the sleeve at least two engagement points. | 06-23-2011 |
20110189377 | Coating for Medical Devices Comprising An Inorganic or Ceramic Oxide and a Therapeutic Agent - The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular, the invention pertains to an implantable medical device, such as an intravascular stem, having a coating comprising an inorganic or ceramic oxide, such as titanium oxide, and a therapeutic agent. | 08-04-2011 |
20120095396 | Drug Eluting Medical Device Utilizing Bioadhesives - A medical balloon having an inner surface and an outer surface comprising a first coating composition comprising at least one therapeutic agent, the first coating composition disposed on the balloon outer surface and forming an interface between the balloon outer surface and the first coating composition and a second coating composition comprising a bioadhesive, the second coating composition disposed on the first coating composition so as to not affect the interface between the balloon outer surface and the first coating composition, the bioadhesive selected so as to adhere to body tissue, and methods of making the same. | 04-19-2012 |