Patent application number | Description | Published |
20090318788 | DETECTION OF CANCER MARKERS - The present invention relates to combining surface molecular imprinting (SMI) with the production of self-assembled monolayers (SAM) of hydroxyl alkanethiolate molecules on gold coated chip surfaces. In this technique, the sensing element is placed on the transducer and the whole assembly can then be miniaturized and integrated into a smart chip. These sensors can detect, nanomolar quantities of complex biomolecules. | 12-24-2009 |
20110171292 | PEPTIDE COMPOSITIONS AND METHODS OF USE - The present invention provides isolated peptides with at least two cysteine residues capable of forming one or more disulfide bonds. Pharmaceutical compositions comprising the isolated peptides of the present invention are also provided. The invention also provides methods for inhibiting, preventing or improving the pathological or clinical manifestations of cancer or an inflammatory disease or disorder in a subject, comprising administering a peptide of the invention. | 07-14-2011 |
20120004175 | INHIBITORS OF NF-KB ACTIVITY - The present invention provides a method for inhibiting NF-κB activity in a subject, the method comprising providing an agent capable of inducing expression of annexin 1, whereby said agent induces expression of annexin 1 and whereby said induced expression of annexin 1 inhibits NF-κB activity. Also provided are annexin 1 mimetics capable of binding to NF-κB and pharmaceutical compositions of such inducing and mimetic agents. | 01-05-2012 |
20120034646 | DETECTION OF H. PYLORI UTILIZING UNLABELED UREA - Disclosed is a method and device for detection of | 02-09-2012 |
20130261066 | TREATMENT OF INFLAMMATORY BOWEL DISEASES USING A TRIPEPTIDE - The present invention provides peptides and peptide conjugates for treating inflammatory bowel diseases, including ulcerative colitis and Crohn's disease. The peptides are derived from annexin-1, can be acetylated or conjugated to fatty acids, may be linear or cyclic, and may comprise D amino acids. Pharmaceutical compositions and methods of use are also disclosed. | 10-03-2013 |
Patent application number | Description | Published |
20090099137 | Anti-Inflammatory Compounds and Uses Thereof - Compounds of the general formula | 04-16-2009 |
20120316139 | ANTI-INFLAMMATORY COMPOUNDS AND USES THEREOF - Compounds of the general formula | 12-13-2012 |
20130225529 | PHOSPHO-ESTER DERIVATIVES AND USES THEREOF - Phospho-ester compounds and pharmaceutical compositions thereof administered by the respiratory and other routes for the prevention and/or treatment of lung and brain cancer and precancerous conditions thereof, for the treatment of pain, for the treatment of skin disorders, for treating and/or preventing inflammation-related diseases, and for the treatment and prevention of cancer. | 08-29-2013 |
20140088044 | PRODUCT COMPRISING A NICOTINE-CONTAINING MATERIAL AND AN ANTI-CANCER AGENT - The invention is directed to a product comprising a nicotine-containing material and an anti-cancer agent. The product is applicable in the treatment and/or prevention of cancer and precancerous conditions as well as for preventing cancer recurrence. | 03-27-2014 |
20140088045 | PRODUCT COMPRISING A NICOTINE-CONTAINING MATERIAL AND AN ANTI-CANCER AGENT - The present invention provides a composition comprising a nicotine-containing material and an anti-cancer agent usable in the treatment and/or prevention or reduction of the risk of cancer and precancerous conditions as well as for preventing or reducing the risk of cancer recurrence. Furthermore, a composition comprising a nicotine-containing material and an anti-inflammatory agent usable in the treatment and/or prevention or reduction of the risk of inflammation, is provided. The nicotine containing composition can also include both an anti-cancer agent and an anti-inflammatory agent A device for administering the composition of the present invention to subjects can be a cigarette, smoking pipe, smokeless tobacco, electronic cigarette, transdermal patch or the like. | 03-27-2014 |
20140121185 | COMPOUNDS AND COMPOSITIONS FOR USE IN THE TREATMENT AND PREVENTION OF CANCER AND PRECANCEROUS CONDITIONS, INFLAMMATION-RELATED DISORDERS, PAIN AND FEVER - Novel compounds and pharmaceutical compositions thereof for the treatment and/or prevention of cancer and precancerous conditions, inflammation-related disorders, pain and fever. | 05-01-2014 |
20140178461 | COMPOUNDS AND COMPOSITIONS FOR USE IN THE TREATMENT AND PREVENTION OF LUNG AND BRAIN CANCER AND PRECANCEROUS CONDITIONS THEREOF - Novel compounds and pharmaceutical compositions thereof administered by the respiratory route for prevention and/or treatment of lung and brain cancer and precancerous conditions thereof. | 06-26-2014 |
20140315834 | COMPOUNDS AND COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF INFLAMMATION-RELATED DISORDERS, PAIN AND FEVER, SKIN DISORDERS, CANCER AND PRECANCEROUS CONDITIONS THEREOF - The present invention provides novel compounds and pharmaceutical compositions for the prevention and/or treatment of cancer and precancerous conditions thereof, for the treatment of pain and fever, for the treatment of skin disorders, and for treating and/or preventing inflammation-related diseases and/or cardiovascular diseases. The compounds of the invention also have analgesic properties and anti-platelet properties. The compounds of the invention may be provided to animals, including mammals and humans, by administering a suitable pharmaceutical dose in a suitable pharmaceutical dosage form. The compounds of the invention have improved efficacy and safety, including higher potency and/or fewer or less severe side effects, than conventional therapies. The compounds of the invention comprise a biologically active moiety or portion (A) that has, or is modified to have at least one carboxyl group. The moiety A is preferably an aliphatic, aromatic or alkylaryl group, preferably derived from a non-steroidal anti-inflammatory drug or NSAID (A). The moiety A is bound to a linker moiety (B) via the carboxyl of group A and a linking atom that is selected from oxygen, nitrogen, and sulphur, to form a carboxylic ester, and amide, or a thioester, bond (X | 10-23-2014 |
Patent application number | Description | Published |
20090222544 | FRAMEWORK FOR JOINT ANALYSIS AND DESIGN OF SERVER PROVISIONING AND LOAD DISPATCHING FOR CONNECTION-INTENSIVE SERVER - The claimed subject matter provides a system and/or a method that facilitates managing a number of active servers in a cluster. A forecast component can predict at least one of login rate or number of connections in the cluster at a future time. A dynamic load analysis component can evaluate dynamic behaviors in login rate and number of connections in the cluster as a result of load dispatching. Moreover, a provisioning component can determine a number of servers in the cluster needed based at least in part on the prediction and dynamic behavior analysis. In addition, the provisioning component can include an additional margin in the number of servers needed in accordance with multiplicative factors. | 09-03-2009 |
20090222562 | LOAD SKEWING FOR POWER-AWARE SERVER PROVISIONING - The claimed subject matter provides a system and/or a method facilitates energy-aware connection distribution among a plurality of servers in a cluster. A set of busy servers in the cluster can be provided that each handle a high number of connections. In addition, a set of tail servers in the cluster can be managed that each maintain a low number of connections. A load skewing component gives priority to at least a subset of the set of busy servers when dispatching new connection requests from a plurality of users. In addition, the load skewing component controls the number of tail servers to maintain a sufficient number for energy-aware operation. | 09-03-2009 |
20120303999 | IMPLEMENTING FAILOVER PROCESSES BETWEEN STORAGE STAMPS - Embodiments of the present invention relate to invoking and managing a failover of a storage account between partitions within a distributed computing environment, where each partition represents a key range of data for the storage account. The partitions affected by the failover include source partitions hosted on a primary storage stamp and destination partitions hosted on a secondary storage stamp, where the storage account's data is being actively replicated from the primary to the secondary storage stamp. Upon receiving a manual or automatic indication to perform the failover, configuring the source partitions to independently perform flush-send operations (e.g., distributing pending messages as a group) and then configuring the destination partitions to independently perform flush-replay operations (e.g., aggressively replaying currently pending transactions). Upon completing the flush-replay operations, designating the secondary storage stamp as a new primary storage stamp such that live traffic is directed to the new primary storage stamp. | 11-29-2012 |
20140289554 | IMPLEMENTING FAILOVER PROCESSES BETWEEN STORAGE STAMPS - Embodiments of the present invention relate to invoking and managing a failover of a storage account between partitions within a distributed computing environment, where each partition represents a key range of data for the storage account. The partitions affected by the failover include source partitions hosted on a primary storage stamp and destination partitions hosted on a secondary storage stamp, where the storage account's data is being actively replicated from the primary to the secondary storage stamp. Upon receiving a manual or automatic indication to perform the failover, configuring the source partitions to independently perform flush-send operations (e.g., distributing pending messages as a group) and then configuring the destination partitions to independently perform flush-replay operations (e.g., aggressively replaying currently pending transactions). Upon completing the flush-replay operations, designating the secondary storage stamp as a new primary storage stamp such that live traffic is directed to the new primary storage stamp. | 09-25-2014 |
Patent application number | Description | Published |
20090038064 | Removable toilet seat cover scale device - A removable toilet seat cover scale device for weighing a person or an object includes, in combination, a toilet seat cover including hinges for hinged attachment to a toilet seat, a scale mechanism connected to the toilet seat cover, the scale mechanism having at least two force sensors located on a bottom of the toilet seat cover for contact with a toilet seat when the toilet seat cover is attached to a toilet seat and is in a closed position. The force sensors transmit the weight force measurements to a processor, which converts the weight force measurements to an accurate total weight measurement, and the processor transmits the accurate total weight measurement to a display. The hinged attachment includes a lock-release mechanism, the lock-release mechanism having lock and a lock-release, the lock-release mechanism having a first position, being a rest position wherein the hinge means is locked into a toilet seat element, and having a second position being an unlocked position for removal of the toilet seat cover from the toilet seat when the lock-release is activated. | 02-12-2009 |
20090119879 | Hinge pin - A hinge pin for hingedly connecting a first element to a second element, which includes: an elongated shaft having an imaginary central axis along its elongation, and having an upper member, a lower member and a divider stop located between the upper member and the lower member, the upper member having a first maximum width measured at a right angle to the imaginary central axis, the lower member having a second maximum width measured at a right angle to the imaginary central axis, and the divider stop having a third maximum width measured at a right angle to the imaginary central axis, wherein the third maximum width is greater than the second maximum width. In some embodiments, the divider stop is the underside of the upper member. | 05-14-2009 |
20100108834 | Multi-purpose hanger - A multi-purpose hanger includes a frame having a plurality of sequential coat hanger-receiving slots. The frame has a door hinge pin connector at one of its first end and second end that includes a connector member and a vertical shaft-receiving orifice for attachment to a door hinge and door hinge pin. The frame has a closet hanger rod hook for attachment to a closet hanger rod. A multi-purpose hanger system includes the aforesaid hanger and a hinge pin with a separate top for the hanger connector and bottom for a door hinge. | 05-06-2010 |