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Rescigno

Gerald Rescigno, Marriotsville, MD US

Patent application numberDescriptionPublished
20090173510MULTISPEED POWER TOOL TRANSMISSION - A clutch arrangement for use in a power tool having a multi-speed transmission assembly. The clutch arrangement includes a clutch member and a follower member. The clutch member is coupled to a member of the transmission assembly that is proximate the torsional input of the transmission assembly and which must be in a non-rotating position to permit the transmission assembly to perform a torque multiplication operation. The follower member is biased into engagement with the clutch member to inhibit relative rotation therebetween. As the clutch member and the transmission member are coupled to one another, the transmission assembly is able to perform a torque multiplication operation. When, however, the torsion that is exerted onto the clutch member is sufficient to overcome the frictional engagement between the follower and clutch members, the clutch member, and the transmission member, rotate, thereby inhibiting the capability of the transmission to continue to perform the torque multiplication operation.07-09-2009
20110073337POWER TOOL WITH TORQUE CLUTCH - A clutch arrangement for use in a power tool having a multi-speed transmission assembly. The clutch arrangement includes a clutch member and a follower member. The clutch member is coupled to a member of the transmission assembly that is proximate the torsional input of the transmission assembly and which must be in a non-rotating position to permit the transmission assembly to perform a torque multiplication operation. The follower member is biased into engagement with the clutch member to inhibit relative rotation therebetween. As the clutch member and the transmission member are coupled to one another, the transmission assembly is able to perform a torque multiplication operation. When, however, the torsion that is exerted onto the clutch member is sufficient to overcome the frictional engagement between the follower and clutch members, the clutch member, and the transmission member, rotate, thereby inhibiting the capability of the transmission to continue to perform the torque multiplication operation.03-31-2011
20120318547POWER TOOL WITH TORQUE CLUTCH - A power tool with a multi-speed transmission and a switch mechanism for shifting the transmission between a plurality of different speed ratios. The switch mechanism includes a single switch member that is slidably mounted on the housing. The power tool further comprises a clutch having a clutch profile that is coupled to a ring gear of the transmission. In some examples, the power tool further comprises a clutch that is configured to interact with a first stage of the transmission.12-20-2012

Patent applications by Gerald Rescigno, Marriotsville, MD US

Maria Rescigno, Milan IT

Patent application numberDescriptionPublished
20120087902Therapeutic Use Of Probiotics - The involvement of intestinal microbiota in the initiation and perpetuation of inflammatory bowel disease is widely accepted. To reestablish the homeostasis of the gut the use of probiotics has been proposed, with however, limited clinical benefit. This invention relates to an assay based on the modulation of the immunological activity in DCs (dendritic cells) by probiotic strains, in particular 04-12-2012

Maria Rescigno, Milano (mi) IT

Patent application numberDescriptionPublished
20130129713METHOD OF ANTIGEN LOADING FOR IMMUNOTHERAPY - It is disclosed a method for obtaining a specific tumor antigen peptide repertoire loaded and/or activated dendritic cell comprising the steps of: a) exposing in suitable conditions a tumor cell expressing said specific tumor antigen peptide repertoire to at least one Pattern Recognition Receptor (PRR) agonist and/or to an inflammatory cytokine to obtain a tumor cell with an increased activity of at least one protein belonging to the group of connexins; b) co-culturing said tumor cell with an increased activity of at least one protein belonging to the group of connexins with dendritic cells, to get specific tumor antigen peptide repertoire loaded and/or activated dendritic cells; Step a) and b) are performed simultaneously or in sequence. The group of connexins preferably consists of connexin 43, connexin 40, connexin 45, connexin 47, connexin 50.05-23-2013
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