Patent application number | Description | Published |
20110046171 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS - This invention concerns arylsulfonyl pyrazoline carboxamidine derivatives as antagonists of 5-ht6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in parkinson's disease, huntington's chorea, schizophrenia, anxiety, depression, manic depression, psychoses, epilepsy, obsessive compulsive disorders, mood disorders, migraine, alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia, binge eating disorders, panic attacks, akathisia, attention deficit hyperactivity disorder, attention deficit disorder, withdrawal from abuse of cocaine, ethanol, nicotine or benzodiazepines, pain, disorders associated with spinal trauma or head injury, hydrocephalus, functional bowel disorder, irritable bowel syndrome, obesity and type-2 diabetes. The compounds have the general formula (1) wherein the symbols have the meanings given in the description. | 02-24-2011 |
20140011775 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS - This invention concerns arylsulfonyl pyrazoline carboxamidine derivatives as antagonists of 5-ht6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in parkinson's disease, huntington's chorea, schizophrenia, anxiety, depression, manic depression, psychoses, epilepsy, obsessive compulsive disorders, mood disorders, migraine, alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia, binge eating disorders, panic attacks, akathisia, attention deficit hyperactivity disorder, attention deficit disorder, withdrawal from abuse of cocaine, ethanol, nicotine or benzodiazepines, pain, disorders associated with spinal trauma or head injury, hydrocephalus, functional bowel disorder, irritable bowel syndrome, obesity and type-2 diabetes. The compounds have the general formula (1) wherein the symbols have the meanings given in the description. | 01-09-2014 |
Patent application number | Description | Published |
20150051239 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS - This invention concerns arylsulfonyl pyrazoline carboxamidine derivatives as antagonists of 5-ht6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in Parkinson's disease, Huntington's chorea, schizophrenia, anxiety, depression, manic depression, psychoses, epilepsy, obsessive compulsive disorders, mood disorders, migraine, Alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia, binge eating disorders, panic attacks, akathisia, attention deficit hyperactivity disorder, attention deficit disorder, withdrawal from abuse of cocaine, ethanol, nicotine or benzodiazepines, pain, disorders associated with spinal trauma or head injury, hydrocephalus, functional bowel disorder, irritable bowel syndrome, obesity and type-2 diabetes. The compounds have the general formula (1) wherein the symbols have the meanings given in the description. | 02-19-2015 |
Patent application number | Description | Published |
20110173757 | CUSHIONING DEVICES AND METHODS - A cushion may be constructed of a spacer material having a top layer, a bottom layer and a plurality of loosely arranged spacer elements that extend between the top and bottom layers so as to maintain the top layer and the bottom layer spaced apart from each other. An elastomeric gel material is incorporated into the top layer and/or the bottom layer. The gel material may also extend into at least a portion of the spacer elements. | 07-21-2011 |
20130111672 | Mattresses Having a Matrix Core of Foam Elements - A mattress is constructed of a core comprising a matrix of foam pieces that are bonded together. The core has a thickness in the range from about 1.5 inches to about 10 inches, and more particularly from about 3 inches to about 8 inches, a density of about 4 pounds to 8 pounds per cubic foot, and an IFD of about 28 to 65. The core has a top surface and a bottom surface. A base layer is coupled to the bottom surface of the core, and a cushion layer is coupled to the top surface. | 05-09-2013 |
20130117935 | MATTRESS COVER - Embodiments of the invention provide covers for bed components, such as mattresses and/or box-springs, which limit bed bug access to the bed component. According to one embodiment, a cover for a bed component may include an opening that provides access to an interior of the cover and through which a bed component (e.g., a mattress or box-spring) may be inserted, a zipper coupled along the opening, a zipper mechanism slidable along the zipper to couple opposing teeth of the zipper to allow the opening to be zipped closed to enclose the bed component within the cover, a first flap foldable and securable over a distal end of the zipper, a second flap foldable and securable over the first flap, and a barrier material disposed between the second flap and the zipper for applying pressure to the zipper to minimize a gap between the zipper and the first flap. | 05-16-2013 |
20130192001 | CONNECTOR SYSTEM FOR MATTRESS - A connector system includes at least one mattress connector that is coupled to a mattress. The mattress connectors are coupled at the head end and at the foot end of the mattress. A topper connector is coupled to a topper at a head end and a foot end of the topper. A plurality of straps are employed to couple the mattress to the topper, with the straps being coupled to the mattress connectors and the proper connectors. | 08-01-2013 |