Patent application number | Description | Published |
20120258516 | System and Methods for Making and Processing Emulsions - An automated on-touch template bead preparation system is provided and includes a membrane-based emulsion generation subsystems, an emulsion PCR (ePCR) thermocycling plate and subsystem, and a continuous centrifugation emulsion breaking and templated bead collection subsystem. The emulsion generation subsystem provides uniformity in the preparation of an inverse emulsion and may be used to create large or small volume inverse emulsions rapidly and reproducibly. An emulsion-generating device is provided that can supply a continuous stream of an inverse emulsion to a thermocycling subsystem, in automated fashion. The ePCR subsystem can continuously thermocycle an inverse emulsion passed therethrough and includes static temperature zones and a consumable thermocycling plate. The continuous centrifugation subsystem can continuously break a thermally cycled inverse emulsion and collect template beads formed in the aqueous microreactor droplets of the inverse emulsion. | 10-11-2012 |
20140100122 | METHODS, COMPOSITIONS AND SYSTEMS FOR SAMPLE DEPOSITION - Methods, compositions, systems, apparatus, and kits are provided for depositing samples onto surfaces. The samples can include one or more particles, and the surface can include one or more reaction chambers. In some embodiments, the depositing can include the use of companion particles in combination with sample particles. | 04-10-2014 |
20140201172 | Using Flow Space Alignment to Distinguish Duplicate Reads - Systems and method for identifying duplicate reads can receive first and second reads, determine if the first and second reads have a same start and end position, determine a binary flow difference, and identify the second read as a duplicate of the first read when the binary flow difference exceeds a threshold. | 07-17-2014 |
Patent application number | Description | Published |
20140201769 | SYSTEMS AND METHODS FOR IDENTIFYING VIDEO SEGMENTS FOR DISPLAYING CONTEXTUALLY RELEVANT CONTENT - A system and method for the identification of specific video segments in a video program, such as certain TV commercials, is presented. A means is described for an accelerated identification of the video segment of interest in conjunction with a means to communicate said information to a process in a remote television system such that the remote television system can anticipate the future start of said video segment of interest and display contextually related material in close proximity to the start of said video segment. | 07-17-2014 |
20140201772 | SYSTEMS AND METHODS FOR ADDRESSING A MEDIA DATABASE USING DISTANCE ASSOCIATIVE HASHING - A system, method and computer program utilize a distance associative hashing algorithmic means to provide a highly efficient means to rapidly address a large database. The indexing means can be readily subdivided into a plurality of independently-addressable segments where each such segment can address a portion of related data of the database where the sub-divided indexes of said portions reside entirely in the main memory of each of a multiplicity of server means. The resulting cluster of server means, each hosting an addressable sector of a larger database of searchable audio or video information, provides a significant improvement in the latency and scalability of an Automatic Content Recognition system, among other uses. | 07-17-2014 |
20140201787 | SYSTEMS AND METHODS FOR IMPROVING SERVER AND CLIENT PERFORMANCE IN FINGERPRINT ACR SYSTEMS - A system and method are disclosed that improve the efficiency and performance of an Automatic Content Recognition (ACR) system. Several approaches are described that may be used alone or in combination to reduce total system computational costs related to the manner in which such an ACR means takes samples, called “fingerprints,” of digital content being played by a television display device and transmits said fingerprints to a remote server to be compared to a database of fingerprints from known programming. Methods are described for implementing such system performance enhancement including varying sampling rates and other resolution metrics during the process of creating such fingerprints and transmitting them to the database server. The system and method disclosed also describes how to reduce the probability that, when compared to samples from already-identified programming, such fingerprints are incorrectly identified as being of programming other than that which they are in fact derived from. | 07-17-2014 |
20140282673 | SYSTEMS AND METHODS FOR REAL-TIME TELEVISION AD DETECTION USING AN AUTOMATED CONTENT RECOGNITION DATABASE - A system and method for the automated real-time detection and processing of commercial messages, public service announcements or similar short-duration, repeated TV programming segments occurring in one or more broadcast video steams is described. A process is utilized that identifies possible commercial segments by identifying discrete video segments that have specific short durations among other attributes. Video segments that appear to have these characteristics are considered likely to be television commercials, promotions, or public service announcements and are stored in a TV Ad database which is separate from the primary television content database. Incoming video from a plurality of television programming sources is process into fingerprints and placed in a master TV content database. At the same time, said incoming programming is tested for matches in a TV ad database. If a match is found, then the presumed TV ad is removed from the master content database. | 09-18-2014 |
Patent application number | Description | Published |
20090211091 | NON-METALLIC COVER FOR A FIXTURE - An assembly includes a fixture including an opening shaped to receive a portion of a turbine engine component. A non-metallic cover is placed over at least a portion of the fixture. The cover facilitates reducing metal to metal contact of the fixture and the turbine engine component when the turbine engine component is installed in the fixture, and facilitates reducing scratching of the turbine engine component. | 08-27-2009 |
20120096715 | NON-METALLIC COVER FOR A FIXTURE - An assembly used in performing a manufacturing process on a turbine engine component includes a turbine engine component and a fixture including an opening shaped to receive a portion of the turbine engine component. The assembly includes a non-metallic cover placed over at least a portion of an external surface of the fixture. The non-metallic cover is visible when positioned over the at least a portion of the external surface of the fixture and is visible when the turbine engine component is received in the fixture opening of the fixture. | 04-26-2012 |
20130206739 | MANUFACTURING METHODS FOR MULTI-LOBED COOLING HOLES - A method for producing a diffusion cooling hole extending between a wall having a first wall surface and a second wall surface includes forming a cooling hole inlet at the first wall surface, forming a cooling hole outlet at the second wall surface, forming a metering section downstream from the inlet and forming a multi-lobed diffusing section between the metering section and the outlet. The inlet, outlet, metering section and multi-lobed diffusing section are formed by laser drilling, particle beam machining, fluid jet guided laser machining, mechanical machining, masking and combinations thereof. | 08-15-2013 |
20130299457 | ELECTRICAL DISCHARGE MACHINING ELECTRODE - An example electrical discharge machining electrode assembly includes an electrode base and an electrode coating containing diamond that is electroplated to the electrode base. | 11-14-2013 |
20140294136 | NON-DESTRUCTIVE INSPECTION OF AN ARTICLE USING CROSS-SECTIONS THROUGH INTERNAL FEATURE - A method of non-destructively inspecting an article includes scanning an article to produce a computerized three-dimensional representation of an internal feature of the article. A measurement characteristic of the internal feature is then generated from a plurality of cross-sections through the computerized three-dimensional representation of the internal feature. The measurement characteristic is then used to determine whether the internal feature meets a design criterion. | 10-02-2014 |
Patent application number | Description | Published |
20100184104 | NANOELECTRONIC-ENZYME LINKED IMMUNOSORBENT ASSAY SYSTEM AND METHOD - The present invention relates to a device and method for determining the presence of a specific compound in solution. The device includes a nanosensor having an electrically conducting pathway between at least a first and second contact. The device also includes a first receptor, suitable for binding a specific compound in the solution, attached to the nanosensor, and a second receptor also suitable for binding the specific compound while the specific compound is bound to the first receptor. The second receptor is attached to an enzyme added to the solution. When the solution having the second receptor is added to the device, and a second compound that is a substrate for the enzyme is subsequently added to the solution, a measured difference in an electrical property in the device before and after the application of the second compound is indicative of the presence of the specific compound in the solution. | 07-22-2010 |
20100297608 | Systems and Methods for CMOS-Compatible Silicon Nano-Wire Sensors with Biochemical and Cellular Interfaces - The systems and methods described herein include a sensor for suitable for sensing chemical and biological substances. The sensor comprises a semiconductor layer formed in or on a substrate and a channel having nano-scale dimensions formed in the semiconductor layer, where the structure creates an electrically conducting pathway between a first contact and a second contact on the semiconductor layer. In certain preferred embodiments, the nano-scale channel has a trapezoidal cross-section with an effective width and exposed lateral faces, where the effective width is selected to have same order of magnitude as a Debye length (L | 11-25-2010 |
20110031389 | System and Method for Trapping and Measuring a Charged Particle in a Liquid - A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed. | 02-10-2011 |
20120107954 | PHYSIOLOGIC SAMPLE PREPARATION FOR NANOSENSORS - The present invention provides a microfluidic purification chip for capturing a biomarker from a physiological solution. The present invention also provides a method of capturing and releasing a biomarker, wherein the biomarker is originally in a physiological solution. The present invention further provides a method of pre-purifying and measuring the concentration of a biomarker in a physiological solution. | 05-03-2012 |
20130026387 | SYSTEM AND METHOD FOR TRAPPING AND MEASURING A CHARGED PARTICLE IN A LIQUID - A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed. | 01-31-2013 |
20130105317 | Electronic Device for Pathogen Detection | 05-02-2013 |
20140128278 | Calibration of Nanostructure Sensors - The present invention relates to uniform nanostructure biosensors and methods of calibrating the response of nanostructure biosensors. The invention overcomes device to device variability that has made quantitative detection difficult. The described biosensors have uniform characteristics that allow for more reliable comparison across devices. The methods of the invention comprise normalizing the initial current rate, as measured by the nanostructure biosensor following the addition of an analyte, to device characteristics of the biosensor. The device characteristics of the biosensor which can be used to normalize the response include baseline current and transconductance. Calibration of responses allows for the generation of calibration curves for use in all devices to quantitatively detect an analyte, without the need for individual device calibration. | 05-08-2014 |
20140191186 | Regenerative Nanosensor Devices - The present invention provides a regenerative nanosensor device for the detection of one or more analytes of interest. In certain embodiments, the device comprises a nanostructure having a reversible functionalized coating comprising a supramolecular assembly. Controllable and selective disruption of the assembly promotes desorption of at least part of the reversible functionalized coating thereby allowing for reuse of the regenerative device. | 07-10-2014 |
20150107999 | Apparatus for Pathogen Detection - An apparatus for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The electric field is applied to at least one electrode having a plurality of concentric rings or concentric arcs extending radially outwards from a center point, electrically connected to a voltage source such that when voltage is applied to the at least one electrode, the concentric rings or concentric arcs alternate in voltage potential. | 04-23-2015 |
Patent application number | Description | Published |
20100042044 | Systems and Methods for Mixing Fluids - Improvements are provided for a syringe-to-syringe mixing system to improve the mixing characteristics of the system. In one embodiment, a mixing apparatus includes opposite fittings for mounting to a pair of syringes. The mixing apparatus defines a fluid passageway therethrough and includes a flow modifying element disposed within the passageway. The flow modifying element is configured to increase the flow velocity, disrupt the fluid flow or introduce turbulence into the fluid flow between the two syringes. In another embodiment, a nozzle element is disposed within the tip of the syringe, the element configured to increase the fluid flow therethrough. The nozzle element can be a nozzle insert removably mounted within the tip, or an integrally formed nozzle within the tip. | 02-18-2010 |
20100178631 | Maxillary Bone Cutting and Injection System and Method of Using the Same - A bone cutting and injecting device for cutting maxillary bone and injecting a filler through the maxillary bone under a subantral membrane to separate the subantral membrane from the maxillary bone and fill the space formed therebetween. The device includes a hollow tubular element having a diameter sized to be inserted into a pilot hole in the maxillary bone, a piston longitudinally displaceable within the hollow tubular element, and a cutter mounted to the piston and operably disposed adjacent the distal end of the hollow tubular element. A fluid path is defined through the hollow tubular element for guiding the filler, and the cutter is configured to redirect the filler in a transverse or radial direction relative to the longitudinal axis of the tubular element. | 07-15-2010 |
20100234813 | MINIMALLY INVASIVE MITRAL VALVE REPAIR METHOD AND APPARATUS - The present invention is directed to an apparatus and method for the stabilization and fastening of two pieces of tissue. A single device may be used to both stabilize and fasten the two pieces of tissue, or a separate stabilizing device may be used in conjunction with a fastening device. The stabilizing device may comprise a probe with vacuum ports and/or mechanical clamps disposed at the distal end to approximate the two pieces of tissue. After the pieces of tissue are stabilized, they are fastened together using sutures or clips. One exemplary embodiment of a suture-based fastener comprises a toggle and suture arrangement deployed by a needle, wherein the needle enters the front side of the tissue and exits the blind side. In a second exemplary embodiment, the suture-based fastener comprises a needle connected to a suture. The needle enters the blind side of the tissue and exits the front side. The suture is then tied in a knot to secure the pieces of tissue. One example of a clip-based fastener comprises a spring-loaded clip having two arms with tapered distal ends and barbs. The probe includes a deployment mechanism which causes the clip to pierce and lockingly secure the two pieces of tissue. | 09-16-2010 |
20130138121 | MINIMALLY INVASIVE MITRAL VALVE REPAIR METHOD AND APPARATUS - The present invention is directed to an apparatus and method for the stabilization and fastening of two pieces of tissue. A single device may be used to both stabilize and fasten the two pieces of tissue, or a separate stabilizing device may be used in conjunction with a fastening device. After the pieces of tissue are stabilized, they are fastened together using sutures or clips. One exemplary embodiment of a suture-based fastener comprises a needle connected to a suture. The needle enters the blind side of the tissue and exits the front side. The suture is then tied in a knot to secure the pieces of tissue. One example of a clip-based fastener comprises a spring-loaded clip having two arms with tapered distal ends and barbs. The probe includes a deployment mechanism which causes the clip to pierce and lockingly secure the two pieces of tissue. | 05-30-2013 |