Patent application number | Description | Published |
20090131347 | IMMUNIZATION-FREE METHODS FOR TREATING ANTIGEN-STIMULATED INFLAMMATION IN A MAMMALIAN HOST AND SHIFTING THE HOST'S ANTIGEN IMMUNE RESPONSIVENESS TO A TH1 PHENOTYPE - The invention relates to methods for preventing or reducing antigen-stimulated, granulocytemediated inflammation in tissue of an antigen-sensitized mammal host by delivering an immunostimulatory oligonucleotide to the host. In addition, methods for using the immunostimulatory oligonucleotides to boost a mammal host's immune responsiveness to a sensitizing antigen (without immunization of the host by the antigen) and shifting the host's immune responsiveness to a Th1 phenotype to achieve various therapeutic ends are provided. Kits for practicing the methods of the invention are also provided. | 05-21-2009 |
20110034541 | Inhibitors of DNA Immunostimulatory Sequence Activity - The invention consists of oligonucleotides which inhibit the immunostimulatory activity of ISS-ODN (immunostimulatory sequence oligodeoxynucleotides) as well as methods for their identification and use. The oligonucleotides of the invention are useful in controlling therapeutically intended ISS-ODN adjuvant activity as well as undesired ISS-ODN activity exerted by recombinant expression vectors, such as those used for gene therapy and gene immunization. The oligonucleotides of the invention also have anti-inflammatory activity useful in reducing inflammation in response to infection of a host with ISS-ODN containing microbes, in controlling autoimmune disease and in boosting host Th2 type immune responses to an antigen. The invention also encompasses pharmaecutically useful conjugates of the oligonucleotides of the invention (including conjugate partners such as antigens and antibodies). | 02-10-2011 |
20110182927 | Inhibitors of DNA Immunostimulatory Sequence Activity - The invention consists of oligonucleotides which inhibit the immunostimulatory activity of ISS-ODN (immunostimulatory sequence oligodeoxynucleotides) as well as methods for their identification and use. The oligonucleotides of the invention are useful in controlling therapeutically intended ISS-ODN adjuvant activity as well as undesired ISS-ODN activity exerted by recombinant expression vectors, such as those used for gene therapy and gene immunization. The oligonucleotides of the invention also have anti-inflammatory activity useful in reducing inflammation in response to infection of a host with ISS-ODN containing microbes, in controlling autoimmune disease and in boosting host Th2 type immune responses to an antigen. The invention also encompasses pharmaceutically useful conjugates of the oligonucleotides of the invention (including conjugate partners such as antigens and antibodies). | 07-28-2011 |
20150258096 | METHODS AND COMPOSITIONS FOR TREATMENT OF TH2-MEDIATED AND TH17-MEDIATED DISEASES - Provided herein, inter alia, are methods drawn to treatment of Th2-mediated and Th17-mediated diseases. Also provided herein is a mouse model that develops Th2 responses to environmental stimuli in a similar manner as human subjects. | 09-17-2015 |
Patent application number | Description | Published |
20090327917 | SHARING OF INFORMATION OVER A COMMUNICATION NETWORK - A method of sharing information associated with a selected application is provided. The method comprises identifying a media type associated with the information, and capturing the information based on the media type. The method further comprises identifying a content type associated with the information, the content type being related to the media type, encoding the information based on the content type, and providing access to the encoded information over a communication network. | 12-31-2009 |
20090327918 | FORMATTING INFORMATION FOR TRANSMISSION OVER A COMMUNICATION NETWORK - A method of formatting information for transmission over a peer-to-peer communication network is provided. The method comprises identifying a graphical nature of the information, and capturing the information based on the graphical nature. The method further comprises identifying a graphical content type associated with the information, and encoding the information based on the graphical content type. | 12-31-2009 |
20110060835 | COMMUNICATING WITH A USER DEVICE IN A COMPUTER ENVIRONMENT - Communicating with a user device in a computer network. A tracker peer is contacted and obtaining a list of peer nodes at a user device. A subset of peer nodes are selected from the list of peer nodes to act as relay nodes for a communication. A first form of communication is transmitted to at least one relay node for the at least one relay node to forward to at least one other user device, wherein the relay node is one of the subset of the peer nodes. The first form of communication is received at the user device from the at least one relay node forwarded from the at least one other user. A second form of communication is transmitted to the at least one relay node for the at least one relay node to forward to the at least one other user device, wherein the relay node is one of the subset of the peer nodes. | 03-10-2011 |
20110066684 | COMMUNICATING WITH A USER DEVICE - Manipulating images on a display of a communication device. Data captured from a first image receiving device is displayed in a first display region disposed in a first position on a display of the communication device. Data captured from a second image receiving device is displayed in a first display region disposed in a second position on the display of the communication device. Selective swapping of said first position of said first display region with said second position of said second display region, upon receiving a selection for said swapping from a user, is enabled. Selective swapping of the data captured from the first image receiving device with data captured from a third image receiving device, upon receiving a selection for the swapping from the user, is enabled. Terminating a first portion of a communication on the communication device while maintaining a second portion of the communication upon receiving a selection for the terminating from the user, is enabled. | 03-17-2011 |
20110066924 | COMMUNICATING IN A COMPUTER ENVIRONMENT - Communicating in a peer-to-peer computer environment. A tracker peer is contacted and a list of peer nodes are obtained at a user device. A subset of peer nodes are selected from the list of peer nodes to act as relay nodes for a communication. An appropriate compression scheme is selected for the communication at the user device. Data is transmitted to at least one relay node for the at least one relay node to forward to at least one other user device, wherein the relay node is one of the subset of the peer nodes. Data is received at the user device from the at least one relay node forwarded from the at least one other user. | 03-17-2011 |
20110173331 | SEAMLESSLY TRANSFERRING A COMMUNICATION - Seamlessly transferring a communication. At least one communication is established between a first device and a second device. The at least one communication is transferred from the second device to a third device without interrupting the at least one communication and without disconnecting the at least one communication from the first device. | 07-14-2011 |
20120254229 | DETERMINING POTENTIAL RELATIONSHIPS BETWEEN INDIVIDUALS - A computer-implemented method for obtaining information corresponding to a first user. The computer-implemented method includes, obtaining information corresponding to a first user, accessing a database comprising information corresponding to a plurality of individuals, based on the information corresponding to a plurality of individuals. The method further includes determining whether a potential relationship exists between a first user and at least one of the plurality of individuals. | 10-04-2012 |
20130090088 | SEAMLESSLY AUTHENTICATING DEVICE USERS - A method for seamlessly authenticating users of a first and second device is described. The method includes: determining a set of first signatures for a first device; generating a set of second signatures for a second device; comparing the set of first signatures with the set of second signatures; and based on the comparing, granting a user authentication status if a difference between the set of first signatures and the set of second signatures is less than a predetermined tolerance threshold, and rejecting the user authentication status if a difference between the set of first signatures and the set of second signatures is more than the predetermined tolerance threshold. | 04-11-2013 |
20130198287 | DETERMINING POTENTIAL RELATIONSHIPS BETWEEN INDIVIDUALS - A computer-implemented method for obtaining information corresponding to a first user. The computer-implemented method includes, obtaining information corresponding to a first user, accessing a database comprising information corresponding to a plurality of individuals, based on the information corresponding to a plurality of individuals. The method further includes determining whether a potential relationship exists between a first user and at least one of the plurality of individuals. | 08-01-2013 |
20130198394 | COMMUNICATING WITH A USER DEVICE - A methods and systems for communicating are disclosed. A request is received at a first device to communicate with a second device. Contact is initiated with the second device via a data center. A first form of communication is transmitted to the second device without requiring the transmitting to be routed through a central server. The first form of communication is received from the second device without requiring the receiving to be routed through a central server. A second form of communication is transmitted to the second device without requiring the transmitting to be routed through a central server. | 08-01-2013 |
20130205163 | COMMUNICATING IN A COMPUTER ENVIRONMENT - Communicating in a peer-to-peer computer environment. A portion of a communication is received from a first user device at a relay peer, wherein the relay peer is one of a list of potential peers and wherein the first user device and a second user device have disparate CPU power and bandwidth capabilities. The portion of the communication is transcoded to comprise a base layer and an enhanced layer. In one embodiment, transcoding encompasses changing the resolution of the communication. The base layer of the portion of the communication is sent to the second user device from the relay peer. The enhanced layer of the portion of the communication is selectively sent to the second user device depending upon a set of capabilities of the second user device. | 08-08-2013 |
20140009475 | ANIMATION IN THREADED CONVERSATIONS - A method for augmenting a threaded conversation between a first device and a second device. The method includes: receiving a selection of a selectable animation, via a selection of a selectable animation representation, at the first device, wherein the selectable animation is configured for augmenting the threaded conversation; and incorporating the selection of the selectable animation into the threaded conversation such that the selectable animation appears in a conversation view of the first device and the second device. | 01-09-2014 |
20150201085 | SEAMLESSLY TRANSFERRING A COMMUNICATION - Seamlessly transferring a communication. At least one communication is established between a first device and a second device. The at least one communication is transferred from the second device to a third device without interrupting the at least one communication and without disconnecting the at least one communication from the first device. | 07-16-2015 |