Patent application number | Description | Published |
20130034870 | METHOD FOR BODILY FLUID SAMPLE TRANSFER DURING ANALYTE DETERMINATION - A method for the transfer of a bodily fluid sample (such as a whole blood sample) during the determination of an analyte (e.g., glucose) in the bodily fluid sample includes applying the bodily fluid sample to a sample collection reservoir of an analytical test strip (for example, an electrochemical-based analytical test strip). During such application, the sample collection reservoir is isolated from fluid communication with a determination chamber of the analytical test strip. The analytical test strip is subsequently inserted into a test meter such that the sample collection reservoir is placed into fluid communication with the determination chamber and such that at least a portion of the bodily fluid sample is consequentially transferred from the sample collection reservoir to the determination chamber. The method further includes determining the analyte in the bodily fluid sample transferred to the determination chamber. | 02-07-2013 |
20130034871 | HAND-HELD TEST METER AND ANALYTICAL TEST STRIP CARTRIDGE COMBINATION - A hand-held test meter and analytical test strip cartridge combination includes a hand-held test meter with a test meter housing and an extractor with a test strip engagement feature, while the analytical test strip cartridge includes a cartridge housing, a test strip presentation mechanism disposed within the cartridge housing, and a plurality of analytical test strips (each with at least one extractor engagement feature) disposed in the cartridge housing. Moreover, the test meter housing is configured for operative engagement with the cartridge housing, the test strip presentation mechanism is configured to present a single analytical test strip from the plurality of analytical test strips for engagement with the extractor, and the extractor and test meter housing are configured such that the extractor is operatively extendable from the test meter housing into the cartridge housing upon engagement of the meter housing with the cartridge housing. In addition, the extractor is also configured such that, upon operative extension, the extractor mechanically engages with the analytical test strip presented by the test strip presentation mechanism via engagement between the test strip engagement feature and the extractor engagement feature, and such that, upon disengagement of the test meter housing from the cartridge housing, the extractor removes the mechanically engaged analytical test strip from the cartridge housing and retracts into the test meter housing. | 02-07-2013 |
Patent application number | Description | Published |
20080312415 | LONG LASTING FUSION PEPTIDE INHIBITORS FOR HIV INFECTION - This invention relates to enfuvirtide peptide derivatives that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to enfuvirtide derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory syncytial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections. | 12-18-2008 |
20090054332 | THOMBOPOIETIN PEPTIDE CONJUGATES - The present invention relates to compounds comprising modified thrombopoietin peptides and conjugates of such modified peptides to serum components, typically serum proteins or peptides. The compounds and conjugates of the invention comprise a reactive group or a residue of a reactive group, which is covalently attached to a modified peptide, optionally through a linking group. The present invention also provides methods for the covalent attachment of a modified peptide to a serum protein or peptide to form a conjugate of the invention. The conjugates of the invention typically exhibit a longer in vivo circulating half-life compared to the corresponding unconjugated peptides. The conjugates of the invention also retain at least some of the biological activity of the unconjugated peptides, and typically exhibit increased biological activity compared to the unconjugated peptides. The present invention also provides methods for the treatment and prevention of a disease or disorder comprising the administration of one or more of the compounds or conjugates of the invention to a subject in need of such treatment or prevention. | 02-26-2009 |
20090088377 | CYSTEIC ACID DERIVATIVES OF ANTI-VIRAL PEPTIDES - This invention relates to C34 peptide derivatives having improved aqueous solubility that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to C34 derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory synctial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections. | 04-02-2009 |
20090088378 | LONG LASTING INHIBITORS OF VIRAL INFECTION - This invention relates to C34 peptide derivatives that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to C34 derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory synctial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections. | 04-02-2009 |
20110313132 | PROCESS FOR THE PRODUCTION OF PREFORMED CONJUGATES OF ALBUMIN AND A THERAPEUTIC AGENT - The present invention provides processes for the production of preformed albumin conjugates. In particular, the invention provides processes for the in-vitro conjugation of a therapeutic compound to recombinant albumin, wherein a therapeutic compound comprising a reactive group is contacted to recombinant albumin in solution to form a conjugate. The processes provide for conjugation to albumin species of increasing homogeneity. The resulting conjugate is purified by chromatography, in particular hydrophobic interaction chromatography comprising phenyl sepharose and butyl sepharose chromatography. | 12-22-2011 |
Patent application number | Description | Published |
20150294410 | SYSTEM FOR COORDINATING RIGHTS TO BORROW TRANSACTIONS - A system includes an order engine that receives a plurality of right to borrow orders. Each of the right to borrow orders includes an asset, an indication of whether a right is sought to either borrow or lend the asset, a quantity of the asset to be borrowed or lended, a rental rate, a start date, and an end date. The system also includes a matching engine that determines that a first of the plurality of right to borrow orders matches with a second of the plurality of right to borrow orders. The system also includes a transaction engine that initiates a transaction associated with the determined first and second right to borrow orders. | 10-15-2015 |
20150294411 | MATCHING ENGINE FOR RIGHTS TO BORROW TRANSACTIONS - A system includes a memory that stores a plurality of right to borrow sell orders. The system also includes an order engine that receive a right to borrow buy order. The system also includes a matching engine that determines that the right to borrow buy order matches with one of the plurality of right to borrow sell orders. Determining a match includes determining that an asset desired for borrowing by the right to borrow buy order matches an asset offered for lending by the determined right to borrow sell order. Determining a match also includes determining that a rental rate offered by the right to borrow buy order is greater than or equal to a rental rate requested by the determined right to borrow sell order. Determining a match also includes determining that a start date associated with a time when the asset is first desired to be borrowed by the right to borrow buy order is between a start date associated with a time when the asset is first offered for lending and an end date associated with a time when the asset is no longer desired to be borrowed by the determined right to borrow sell order. | 10-15-2015 |
20150294412 | MATCHING ENGINE FOR POLYMORPHIC RIGHTS TO BORROW TRANSACTIONS - According to yet another embodiment, a system includes an order engine that receives, from a first party, a polymorphic right to borrow sell order. The polymorphic right to borrow sell order includes a first quantity of an asset that is offered for lending, a start date associated with a time when the asset is first offered for lending, an end date associated with a time when the asset is no longer offered for lending, one or more first terms, and one or more second terms different from the one or more first terms. The order engine also receives, from a different party, a right to borrow buy order that indicates a quantity of the asset that is desired for borrowing. The system also includes a matching engine that matches, based upon the one or more first terms and the one or more second terms, the one or more first terms of the polymorphic right to borrow sell order with the right to borrow buy order. The system also includes a transaction engine that determines a transaction associated with the one or more first terms of the polymorphic right to borrow sell order and the right to borrow buy order and initiates the transaction. | 10-15-2015 |