Qu, US
Bingyu Qu US
Patent application number | Description | Published |
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20110292906 | METHOD, APPARATUS, AND SYSTEM FOR COORDINATED MULTI-POINT TRANSMISSION - A method, an apparatus, and a system for Coordinated Multi-Point (CoMP) transmission are provided, which can effectively improve the transmission reliability over the control channel and flexibility of the application. The method includes: allocating different resources to a control channel carrying coordination information and a data channel, and performing CoMP transmission over the control channel and the data channel by using the allocated different resources. The technical solutions provided in the present invention are applicable to an Orthogonal Frequency Division Multiplexing (OFDM) system, a Code Division Multiple Access (CDMA) system, a Time Division Multiple Access (TDMA) system, or other mobile communication systems. | 12-01-2011 |
Bo Qu, Brookfield, CT US
Patent application number | Description | Published |
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20110130567 | STEROSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS - A process for stereoselective synthesis of a compound of Formula (X) | 06-02-2011 |
20120277455 | NOVEL CHIRAL PHOSPHORUS LIGANDS - The invention relates to a series of novel chiral phosphorus ligands of formulae (Ia) and (Ib): wherein R, 1-rR>4 and X are as defined herein. The invention also relates to chiral metal complexes prepared with these chiral phosphorus ligands. The chiral metal complexes are useful as catalysts for carrying out asymmetric hydro genation. | 11-01-2012 |
20130137902 | Monophosphorus Ligands And Their Use In Cross-Coupling Reactions - Phosphine ligands of the formula Ia, IB and mixtures thereof. | 05-30-2013 |
20130211089 | INDENOPYRIDINE DERIVATIVES - Disclosed is a compound of formula (I) | 08-15-2013 |
20140094609 | PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR - The present invention is directed to an improved process for the preparation of Compounds of Formula (I), which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid, which is useful in the treatment of HIV infection. | 04-03-2014 |
20140094610 | PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR - The present invention is directed to an improved process for the preparation of Compounds of Formula (I) or salts thereof which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid or salt thereof which is useful in the treatment of HIV infection. | 04-03-2014 |
20140107343 | INDENOPYRIDINE DERIVATIVES - Disclosed is a compound of formula (I) | 04-17-2014 |
20150018555 | NOVEL CHIRAL NITROGEN-PHOSPHORUS LIGANDS AND THEIR USE FOR ASYMMETRIC HYDROGENATION OF ALKENES - The invention relates to a series of novel chiral nitrogen-phosphorus ligands of formulae (Ia) and (Ib): | 01-15-2015 |
Cheng-Kui Qu, Solon, OH US
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20110257184 | SHP-2 PHOSPHATASE INHIBITOR - A method of treating SHP-2 phosphatase associated diseases in a subject includes administering a SHP-2 inhibitor to the subject. | 10-20-2011 |
Chuanxing Qu, Scotch Plains, NJ US
Patent application number | Description | Published |
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20080200445 | Heterocyclic aspartyl protease inhibitors - Disclosed are compounds of the formula I | 08-21-2008 |
20120231017 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 09-13-2012 |
20120231018 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 09-13-2012 |
20120276118 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 11-01-2012 |
Di Qu, Ada, MI US
Patent application number | Description | Published |
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20100214421 | Skin Color Measurement - A process for measuring skin color parameters from a digital photograph using novel color correction algorithms is described. The process includes measuring color values of a digital color photo, correcting the color deviation of each picture to that of a standard color, and converting the corrected RGB values and generating an output that is useful to L*a*b* values to describe changes in the color properties of the photographed skin. | 08-26-2010 |
20120076876 | CHIA SEED EXTRACT AND RELATED METHOD OF MANUFACTURE - Ethanolic chia ( | 03-29-2012 |
20130136708 | CHIA SEED EXTRACT AND RELATED METHOD OF MANUFACTURE - Ethanolic chia ( | 05-30-2013 |
20130245459 | Quantification of Under-Eye Skin Color - Methods for quantitative measurement of under eye dark circles and other color related phenomena in eye area skin are described. The methods can be used to quantify the clinical efficacy of skin care products. | 09-19-2013 |
20130272571 | HUMAN SUBMENTAL PROFILE MEASUREMENT - An imaging system captures images of a human submental profile in a dimension controlled environment and utilizes image analysis algorithms for detecting submental changes. Instead of implementing a strict posture control of a subject, the imaging system allows the subject to freely move his/her head in an up-and-down direction and a high speed camera captures this movement through a series of images at varying head-to-shoulder angles. The image analysis algorithms may accurately compare before and after images at similar head-to-shoulder angles to identify changes in a human submental profile using a series of measurements and checkpoints. | 10-17-2013 |
20150030243 | CHART FOR EVALUATING SKIN COLOR AND ITS APPLICATION TO EFFICACY EVALUATION OF ANTI-AGING AND SKIN LIGHTENING PRODUCTS - The present invention relates to charts, stacks and methods for evaluating skin color of a mammalian subject. The chart may include a substrate and an indicia visible from a first side of the substrate that includes a plurality of images of mammalian skin tones having varying degrees of yellowness, wherein each indicia is correlated with an index value. Also, the present invention relates to packaged topical cosmetic products that include a skin chart as well as to methods for evaluating anti-aging and skin lightening products. | 01-29-2015 |
Dongxia Qu, Princeton, NJ US
Patent application number | Description | Published |
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20090059235 | Rotationally Asymmetric Chaotic Optical Multi-Pass Cavity - The present invention relates to a rotationally asymmetric chaotic optical multi-pass cavity useful in optical gas sensing spectroscopy, optical delay lines, and laser amplification systems, for example. The cavity may include a single closed mirror having a light reflective surface that is deformed in two orthogonal directions and more particularly, but not exclusively, in the shape of a quadrupole in both horizontal and vertical planes. The cavity includes a light entry port and a light exit port which may be the same or separate ports, as well as a gas inlet and a gas outlet. The optical path length, the beam divergence rate, and the spot pattern are controlled by selecting the cavity deformation coefficients and the input beam direction to achieve the desired beam path and beam quality. | 03-05-2009 |
Fucheng Qu, Carmel, IN US
Patent application number | Description | Published |
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20090270460 | FXR AGONISTS - Compounds of formula wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases. | 10-29-2009 |
20130303471 | NOVEL PYRAZOLE COMPOUNDS - The present invention provides a compound of Formula II: | 11-14-2013 |
20140100179 | NOVEL UREA COMPOUNDS - The present invention provides a compound of Formula I: | 04-10-2014 |
20140162967 | NOVEL PYRAZOLE COMPOUNDS - The present invention provides a compound of Formula II: | 06-12-2014 |
20140296171 | NOVEL UREA COMPOUNDS - The present invention provides a compound of Formula I: | 10-02-2014 |
Guang Qu, Sicklerville, NJ US
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20130072548 | Scalable Manufacturing Platform for Viral Vector Purification and Viral Vectors So Purified for Use in Gene Therapy - Methods for preparing highly purified AAV vector formulations are provided. The highly pure AAV formulations described herein are superior for clinical use. | 03-21-2013 |
Haibo Qu, Storrs, CT US
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20110287167 | CERAMIC COATING AND METHOD OF PREPARATION THEREOF - A ceramic coating with gradient density/porosity and/or incorporated biologically active agents can be fabricated on the surface of substrates, including the surface of implantable medical devices. | 11-24-2011 |
Haibo Qu, Secane, PA US
Patent application number | Description | Published |
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20090130168 | CERAMIC/STRUCTURAL PROTEIN COMPOSITES AND METHOD OF PREPARATION THEREOF - Ceramic/structural protein composite scaffolds and their preparation in a simple one-step process are shown. | 05-21-2009 |
20090130456 | CERAMIC/STRUCTURAL PROTEIN COMPOSITES AND METHOD OF PREPARATION THEREOF - Ceramic/structural protein composites and methods of preparation are disclosed, including coatings and films. Ceramic/structural protein coatings can be fabricated on the surface of substrates, including the surface of implantable medical devices. | 05-21-2009 |
20120003280 | CERAMIC/STRUCTURAL PROTEIN COMPOSITES AND METHOD OF PREPARATION THEREOF - Ceramic/structural protein composites and methods of preparation are disclosed, including coatings and films. Ceramic/structural protein coatings can be fabricated on the surface of substrates, including the surface of implantable medical devices. | 01-05-2012 |
Hongwei Qu, Rochester Hills, MI US
Patent application number | Description | Published |
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20110140216 | Method of wafer-level fabrication of MEMS devices - The present disclosure relates to a method of fabricating a micromachined CMOS-MEMS integrated device as well as the devices/apparatus resulting from the method. In the disclosed method, the anisotropic etching (e.g., DRIE) for isolation trench formation on a MEMS element is performed on the back side of a silicon wafer, thereby avoiding the trench sidewall contamination and the screen effect of the isolation beams in a plasma etching process. In an embodiment, a layered wafer including a substrate and a composite thin film thereon is subjected to at least one (optionally at least two) back side anisotropic etching step to form an isolation trench (and optionally a substrate membrane). The method overcomes drawbacks of other microfabrication processes, including isolation trench sidewall contamination. | 06-16-2011 |
20120067709 | MEMS SWITCH WITH LATCH MECHANISM - A MEMS switch includes a latch mechanism, first and second electrical conductors, a first latch actuator, a second latch actuator, and an axial actuator. The latch mechanism may include a transfer rod and a contact member, the contact member extending radially outwardly from a position along the axial length of the transfer rod. The first and second electrical conductors may extend along, and may be radially offset from, a portion of the transfer rod. The first latch actuator may include a first latch pin, and the second latch actuator may include a second latch pin, the first and second latch actuators being configured to move toward and away from the transfer rod, and the first and second latch pins configured to engage the contact member. The at least one axial actuator may be configured to move the contact member towards and away from the first and second electrical conductors. | 03-22-2012 |
Huiming Qu, White Plains, NY US
Patent application number | Description | Published |
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20110238460 | Dynamic Pricing of a Resource - A method of dynamic pricing of a resource is presented. For example, the method includes determining a set of anticipated demands for one or more users to acquire the resource according to uncertainty of the one or more users in preferring one or more certain time periods of a plurality of time periods for acquiring the resource. Prices for the resource differ between at least two of the plurality of time periods. Each anticipated demand of the set is associated with a different one of the plurality of time periods. The method further includes setting prices for the resource during each of the plurality of time periods according to the determined set of anticipated demands. The determining of the set of anticipated demands and/or the setting of prices are implemented as instruction code executed on a processor device. | 09-29-2011 |
20120004937 | Reservation System with Graphical User Interface - Techniques for providing a reservation system are provided. The techniques include displaying a scalable visualization object, wherein the scalable visualization object comprises an expanded view element of the reservation system depicting information in connection with a selected interval of time and a compressed view element of the reservation system depicting information in connection with one or more additional intervals of time, maintaining a visual context between the expanded view and the compressed view within the visualization object, and enabling a user to switch between the expanded view and the compressed view to facilitate use of the reservation system. | 01-05-2012 |
20120042256 | HIGH PERFORMANCE COMPUTING AS A SERVICE - A scheduling system and method for high-performance computing (HPC) applications includes a network management component stored in physical memory and executed by a processor. The management component is configured to transform HPC resources into a schedulable resource catalog by transforming multi-dimensional HPC resources into a one dimension versus time resource catalog with a dependent graph structure between resources such that HPC resources are enabled to be provisioned into a service environment with predictable provisioning using the resource catalog. A graphical user interface component is coupled to the network management component and configured to provide scheduling visibility to entities and to enable a plurality of different communication modes for scheduling and communication between entities. | 02-16-2012 |
20120042320 | SYSTEM AND METHOD FOR DYNAMIC RESCHEDULING OF MULTIPLE VARYING RESOURCES WITH USER SOCIAL MAPPING - A system and method for scheduling resources includes a memory storage device having a resource data structure stored therein which is configured to store a collection of available resources, time slots for employing the resources, dependencies between the available resources and social map information. A processing system is configured to set up a communication channel between users, between a resource owner and a user or between resource owners to schedule users in the time slots for the available resources. The processing system employs social mapping information of the users or owners to assist in filtering the users and owners and initiating negotiations for the available resources. | 02-16-2012 |
20120324470 | SYSTEM AND METHOD FOR DYNAMIC RESCHEDULING OF MULTIPLE VARYING RESOURCES WITH USER SOCIAL MAPPING - A system and method for scheduling resources includes a memory storage device having a resource data structure stored therein which is configured to store a collection of available resources, time slots for employing the resources, dependencies between the available resources and social map information. A processing system is configured to set up a communication channel between users, between a resource owner and a user or between resource owners to schedule users in the time slots for the available resources. The processing system employs social mapping information of the users or owners to assist in filtering the users and owners and initiating negotiations for the available resources. | 12-20-2012 |
20130275993 | SYSTEM AND METHOD FOR DYNAMIC RESCHEDULING OF MULTIPLE VARYING RESOURCES WITH USER SOCIAL MAPPING - A system and method for scheduling resources includes a memory storage device having a resource data structure stored therein which is configured to store a collection of available resources, time slots for employing the resources, dependencies between the available resources and social map information. A processing system is configured to set up a communication channel between users, between a resource owner and a user or between resource owners to schedule users in the time slots for the available resources. The processing system employs social mapping information of the users or owners to assist in filtering the users and owners and initiating negotiations for the available resources. | 10-17-2013 |
Huiming Qu, Hawthorne, NY US
Patent application number | Description | Published |
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20110145261 | EFFICIENT CALCULATION OF NODE PROXIMITY ON GRAPHS WITH SIDE INFORMATION - In a computerized data mining context, user input relating to positive and negative information is incorporated into node proximity measurements on a weighted, directed graph. Random walk results are updated without a full matrix inversion by using selective update to a low rank approximation and to inversion results. | 06-16-2011 |
20110145262 | MEASURING NODE PROXIMITY ON GRAPHS WITH SIDE INFORMATION - In a computerized data mining context, user input relating to positive and negative information is incorporated into node proximity measurements on a weighted, directed graph. Starting from a source node, links are added to nodes for which positive feedback is received. Where negative information is received, a sink node is substituted for nodes receiving negative information. Nodes neighboring that sink node have links added to the sink. These changes yield an altered graph. Afterwards, proximity information is determined from the altered graph. | 06-16-2011 |
Jian Qu, Austin, TX US
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20090154483 | A 3-LEVEL QUEUING SCHEDULER SUPPORTING FLEXIBLE CONFIGURATION AND ETHERCHANNEL - In one embodiment, a scheduler for a queue hierarchy only accesses sub-groups of bucket nodes in order to determine the best eligible queue bucket to transmit next. Etherchannel address hashing is performed after scheduling so that an Etherchannel queue including a single queue in the hierarchy is implemented to guarantee quality of service. | 06-18-2009 |
Jianmin Qu, Atlanta, GA US
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20090314080 | Method for measuring reactor bed level from active acoustic measurement and analysis - The present invention is a non-intrusive method to determine the fluid level in a vessel. In a preferred embodiment, the vessel is a delayed coker drum in a refinery. Waves are generated in the vessel from an outside source. For wall vibration generated in the frequency range of 1-20,000 Hz, accelerometers on the exterior wall of the vessel measures the attenuation of the vibration modes of the vessel. The fluid level can related to the attenuation of the vibration mode. For wall vibration generated in the ultrasonic range, the wave traveling in the vessel wall are guided waves. The guided wave will leak energy into the fluid inside the vessel and will attenuate depending on the fluid level. Ultrasonic receivers on the outside of the vessel measure the attenuation. The fluid level can be related attenuation of the ultrasonic waves. | 12-24-2009 |
Jing Qu, Reston, VA US
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20120071178 | Mobile Network Presence Service with Load-Based Notification Throttling - Methods and systems are described for providing a presence service that is useful for mobile telecommunications devices. A plurality of outgoing presence updates are sent to a presence client. The system monitors the level of network traffic and determines whether the client is in a region of high network load, and if so, the system throttles the outgoing presence updates during the condition of high network load. The level of throttling may depend at least in part on the amount of time that has elapsed since the presence client began a presence session, and/or the amount of time that has elapsed since an incoming presence update was received from the presence client. In determining the latter amount of elapsed time, the system may consider only the amount of time elapsed since an incoming non-automatic presence update was received from the presence client. | 03-22-2012 |
20120225666 | Method and System for Use of a Trusted Server to Facilitate Location Determination - Disclosed is a method and system for use of a trusted server such as an over-the-air provisioning server to facilitate mobile location determination. If a mobile location server (MLS) sends a location-determination message to a mobile station and does not receive a response back from the mobile station, there is a chance that the mobile station is not provisioned with a correct address of the MLS and that the mobile station therefore did not respond. To help jump start the location-determination process, the MLS may respond to that situation by instead causing a trusted server such as an over-the-air-service-provisioning (OTASP) server to send a location-determination message to the mobile station, triggering a response from the mobile station. | 09-06-2012 |
Jufeng Qu, West Bloomfield, MI US
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20080294587 | SYSTEM AND METHOD FOR RULE SET VALIDATION - A system, method, and computer program for validating a rule set for applicable checks of a part, comprising querying a validation rule set; correlating a part data to said validation rule set; comparing a part against said part data; and whereby said part is approved at an event, and appropriate means and computer-readable instructions. | 11-27-2008 |
Jun Qu, Knoxville, TN US
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20100059041 | Oven Rack Having Integral Lubricious, Dry Porcelain Surface - A lubricious glass-coated metal cooking article capable of withstanding repeated heating and cooling between room temperature and at least 500° F. without chipping or cracking the glass coating, wherein the glass coating includes about 0.1 to about 20% by weight of a homogeneously distributed dry refractory lubricant material having a particle size less than about 200 μm. The lubricant material is selected from the group consisting of carbon; graphite; boron nitride; cubic boron nitride; molybdenum (FV) sulfide; molybdenum sulfide; molybdenum (IV) selenide; molybdenum selenide, tungsten (IV) sulfide; tungsten disulfide; tungsten sulfide; silicon nitride (Si | 03-11-2010 |
20100252146 | TITANIUM ALUMINIDE INTERMETALLIC ALLOYS WITH IMPROVED WEAR RESISTANCE - The invention is directed to a method for producing a titanium aluminide intermetallic alloy composition having an improved wear resistance, the method comprising heating a titanium aluminide intermetallic alloy material in an oxygen-containing environment at a temperature and for a time sufficient to produce a top oxide layer and underlying oxygen-diffused layer, followed by removal of the top oxide layer such that the oxygen-diffused layer is exposed. The invention is also directed to the resulting oxygen-diffused titanium aluminide intermetallic alloy, as well as mechanical components or devices containing the improved alloy composition. | 10-07-2010 |
20120175266 | METHOD FOR SYNTHESIS OF TITANIUM DIOXIDE NANOTUBES USING IONIC LIQUIDS - The invention is directed to a method for producing titanium dioxide nanotubes, the method comprising anodizing titanium metal in contact with an electrolytic medium containing an ionic liquid. The invention is also directed to the resulting titanium dioxide nanotubes, as well as devices incorporating the nanotubes, such as photovoltaic devices, hydrogen generation devices, and hydrogen detection devices. | 07-12-2012 |
Jun Qu, Oak Ridge, TN US
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20120094192 | COMPOSITE NANOWIRE COMPOSITIONS AND METHODS OF SYNTHESIS - Nanowire array compositions in which nanowires containing at least one Group IV metal (e.g., Si or Ge) in a single layer or core-shell nanowire structure, wherein, in particular embodiments, the nanowires have a transition metal core and/or are surrounded by or embedded within a metal oxide or metal oxide-ionic liquid ordered host material. The nanowire compositions are incorporated into the anodes of lithium ion batteries. Methods of preparing the nanowire compositions, particularly by low temperature methods, are also described. | 04-19-2012 |
20120315399 | METHOD OF MAKING NANOPARTICLE REINFORCED METAL MATRIX COMPONENTS - A method of making a nanoparticle reinforced metal matrix component is provided. The method involves solid state processing nanoparticles into a metal matrix material at solid state processing conditions to form a master alloy. At least a portion of the master alloy is added to a mass of metal melt to produce the nanoparticle reinforced metal matrix component. | 12-13-2012 |
Jun Qu, Oakridge, TN US
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20130081679 | MULTIJUNCTION HYBRID SOLAR CELL INCORPORATING VERTICALLY-ALIGNED SILICON NANOWIRES WITH THIN FILMS - A low-cost method is provided for forming a photovoltaic device, which is a high-performance nanostructured multijunction cell. The multiple P-N junctions or P-I-N junctions are contiguously joined to form a single contiguous P-N junction or a single contiguous P-I-N junction. The photovoltaic device integrates vertically-aligned semiconductor nanowires including a doped semiconductor material with a thin silicon layer having an opposite type of doping. This novel hybrid cell can provide a higher efficiency than conventional photovoltaic devices through the combination of the enhanced photon absorptance, reduced contact resistance, and short carrier transport paths in the nanowires. Room temperature processes or low temperature processes such as plasma-enhanced chemical vapor deposition (PECVD) and electrochemical processes can be employed for fabrication of this photovoltaic device in a low-cost, scalable, and energy-efficient manner. | 04-04-2013 |
Junya Qu, Collegeville, PA US
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20120088767 | BENZIMIDAZOLE DERIVATIVES AS PI3 KINASE INHIBITORS - This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kβ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer. | 04-12-2012 |
20130196990 | Benzimidazole Derivatives As PI3 Kinase Inhibitors - This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer. | 08-01-2013 |
20130197221 | Benzimidazole Derivatives As PI3 Kinase Inhibitors - This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer. | 08-01-2013 |
20140018534 | Benzimidazole Derivatives As PI3 Kinase Inhibitors - This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kβ, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer. | 01-16-2014 |
20140142321 | Benzimidazole Derivatives As PI3 Kinase Inhibitors - This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer. | 05-22-2014 |
20140187545 | Pyrazolopyrimidine Derivatives As PI3 Kinase Inhibitors - PI3Kβ selective compounds having the structure | 07-03-2014 |
20140378456 | Benzimidazole Derivatives As PI3 Kinase Inhibitors - This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer. | 12-25-2014 |
Kevin Qu US
Patent application number | Description | Published |
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20110269162 | UBIQUITIN PROTEASOME SYSTEM PROFILING FOR DIAGNOSIS OF CHRONIC LIVER DISEASE - Provided herein are methods for the diagnosis, staging, prognosis, or management of liver disease, e.g. chronic liver disease, and other diseases using profiles of the ubiquitin-proteasome system determined from acellular body fluids or cell-containing samples. Further provided are methods of predicting response to therapy in certain populations of patients with liver disease. | 11-03-2011 |
Liangti Qu, Kettering, OH US
Patent application number | Description | Published |
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20090011232 | ALIGNED CARBON NANOTUBES FOR DRY ADHESIVES AND METHODS FOR PRODUCING SAME - A nanocomposite dry adhesive. The nanocomposite dry adhesive includes a substrate; and an array of vertically aligned single-walled carbon nanotubes or vertically aligned multi-walled carbon nanotubes on the substrate, wherein the nanocomposite dry adhesive utilizes the array of single-walled carbon nanotubes or multi-walled carbon nanotubes as synthesized, the as synthesized single-walled carbon nanotubes being substantially free of randomly entangled nanotube segments on top of the vertically aligned single-walled carbon nanotubes, the as synthesized multi-walled carbon nanotubes having randomly entangled nanotube segments on top of the vertically aligned multi-walled carbon nanotubes; wherein the dry adhesive has a normal adhesion strength of at least about 5 N·cm | 01-08-2009 |
Liangti Qu, Dayton, OH US
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20110024717 | METHOD FOR PREFERENTIAL GROWTH OF SEMICONDUCTING VERTICALLY ALIGNED SINGLE WALLED CARBON NANOTUBES - A method and system for the preferential growth of semiconducting vertically-aligned single-walled carbon nanotubes (VA-SWNTs) is provided. The method combines the use of plasma-enhanced chemical vapor deposition at low pressure with rapid heating. The method provides a high yield of up to approximately 96% semiconducting SWNTs in the VA-SWNT array. The as-synthesized semiconducting SWNTs can be used directly for fabricating field effect transistor (FET) devices without the need for any post-synthesis purification or separation. | 02-03-2011 |
Lianhua Qu, Pittsburgh, PA US
Patent application number | Description | Published |
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20100270504 | PHOTOLUMINESCENT METAL NANOCLUSTERS - Nanoclusters comprising a metal core and outer ligand layer and methods of making and use them are disclosed. The nanoclusters have properties which are tunable by virtue of adjusting various aspects of the reaction. | 10-28-2010 |
20100283034 | Concentration - gradient alloyed semiconductor quantum dots, LED and white light applications - The present invention involves concentration-gradients alloyed quantum dots that have shell modifications and ligands that lower the barrier for electronic quantum dot activation, and electronic and photonic applications of such quantum dots. The present invention also describes emissive layers using such quantum dots in electronic applications. | 11-11-2010 |
20120241682 | CONGLOMERATED SEMICONDUCTOR NANOCRYSTALS - The present invention is directed to compositions comprising conglomerated semiconductor nanocrystals, methods of making conglomerated semiconductor nanocrystals, and methods of using conglomerated semiconductor nanocrystals. Conglomerated semiconductor nanocrystals can be prepared by agitation in solutions comprising one or more nonpolar solvents, or by crosslinking to a variety of polymers. The invention also includes methods of preparing hydrophilic conglomerated semiconductor nanocrystals by enclosing them within a hydrophilic polymer “cage.” Conglomerated semiconductor nanocrystals are useful in a variety of fluorescence based detection systems. | 09-27-2012 |
20130039859 | PASSIVATED NANOPARTICLES - Passivated semiconductor nanoparticles and methods for the fabrication and use of passivated semiconductor nanoparticles is provided herein. | 02-14-2013 |
20140339497 | STABILIZED NANOCRYSTALS - Fluorescent semiconductor nanocrystals and quantum dots having an inorganic coating on the outermost surface of the nanocrystal are described herein as well as methods for preparing and using such nanocrystals and quantum dots. Devices in which such nanocrystals and quantum dots are used are also described. | 11-20-2014 |
Lin Qu, Webster, TX US
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20110129813 | 2'-BRANCHED NUCLEOSIDES AND FLAVIVIRIDAE MUTATION - The present invention discloses a method for the treatment of Flaviviridae infection that includes the administration of a 2′-branched nucleoside, or a pharmaceutically acceptable prodrug and/or salt thereof, to a human in need of therapy in combination or alternation with a drug that directly or indirectly induces a mutation in the viral genome at a location other than a mutation of a nucleotide that results in a change from serine to a different amino acid in the highly conserved consensus sequence, XRX | 06-02-2011 |
20140286900 | 2'-BRANCHED NUCLEOSIDES AND FLAVIVIRIDAE MUTATION - The present invention discloses a method for the treatment of Flaviviridae infection that includes the administration of a 2′-branched nucleoside, or a pharmaceutically acceptable prodrug and/or salt thereof, to a human in need of therapy in combination or alternation with a drug that directly or indirectly induces a mutation in the viral genome at a location other than a mutation of a nucleotide that results in a change from serine to a different amino acid in the highly conserved consensus sequence, XRX | 09-25-2014 |
Liyan Qu, Lincoln, NE US
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20130320772 | RECHARGEABLE MULTI-CELL BATTERY - A method for power management of a multi-cell battery includes identifying a desired power value and voltage value, determining a battery voltage value and a battery current value for a battery, determining a number of battery banks from a plurality of battery banks to use for the battery, where each battery bank includes one or more battery cells (or battery modules), checking availability of each of the one or more battery cells (or battery modules), selecting one or more battery banks from the plurality of battery banks, where the selection of a battery bank is based on the availability of the battery cells (or battery modules) included in the battery pack, and a quantity of the selected battery banks is equal to the determined number of battery banks, and connecting the available battery cells (or battery modules) in the selected one or more battery banks to form the battery. | 12-05-2013 |
Ning Qu, Pittsburgh, PA US
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20100031360 | Systems and methods for preventing unauthorized modification of an operating system - Systems and methods are provided for preventing unauthorized modification of an operating system. The system includes an operating system comprised of kernel code for controlling access to operation of a processing unit. The system further includes an enforcement agent executing at a higher privilege than the kernel code such that any changes to the kernel code are approved by the enforcement agent prior to execution. | 02-04-2010 |
Peng Qu, Austin, TX US
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20080299683 | ESTIMATING YIELD FLUCTUATION FOR BACK-END PLANNING - A method for production planning includes receiving a first order quantity of a first device. A first yield estimate of the first device from a production line is determined. The first yield estimate is adjusted based on a first confidence factor associated with the first order quantity. A dispatch quantity for processing in the production line is determined based on the first order quantity and the adjusted first yield estimate. | 12-04-2008 |
20090171492 | METHOD AND APPARATUS FOR REDUCING SETUPS DURING TEST, MARK AND PACK OPERATIONS - A method includes determining production targets for devices of different types in a production line. A queue level of devices of a first type that have completed performance of a first operation configured in accordance with a first setup state in the production line and await performance of a second operation in the production line is determined. Based on the determined queue level, a second type of device is selected for subsequent processing in the first operation based on the production targets and a setup time associated with configuring the first operation from the first setup state to a second setup state associated with the second type of device. The first operation is configured in accordance with the second setup state for processing devices of the second type. | 07-02-2009 |
20090299678 | METHOD AND APPARATUS FOR DETERMINING A PRODUCT LOADING PLAN FOR A TESTING SYSTEM - A method for determining a loading plan for a testing system includes determining demand quotas for a plurality of devices to be processed through the testing system. Each demand quota specifies a number of required devices and an associated performance specification. A bin classification distribution for devices processed through the testing system is estimated. Each device has an associated product type. Each bin classification indicates a performance grade of the associated devices. A number of devices matching each performance specification exiting the testing system is estimated based on the bin classification distribution. A device loading plan specifying a count of devices for each of a plurality of the product types to be dispatched to the testing system to provide the estimated number of devices matching each performance specification exiting the testing system to substantially meet the demand quota associated with each performance specification is determined. | 12-03-2009 |
Peter Qiang Qu, New Market, MD US
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20120149603 | SAMPLE ANALYSIS SYSTEM - An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber. | 06-14-2012 |
20120196767 | MICROARRAY BASED SAMPLE DETECTION SYSTEM - A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot. | 08-02-2012 |
20140287954 | MICROARRAY BASED SAMPLE DETECTION SYSTEM - A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot. | 09-25-2014 |
Pingping Qu, Issaquah, WA US
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20120015906 | USES OF BORTEZOMIB IN PREDICTING SURVIVAL IN MULTIPLE MYELOMA PATIENTS - The present invention provides a method of predicting outcome of treatment for multiple myeloma based on determining certain cytogenetic anomalies and considering gene expression profiling risks. Also provided are statistical methods employed to define variables independently impacting outcomes. Further provided is method of treatment of myeloma patients. | 01-19-2012 |
Qi Qu, Houston, TX US
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20130041587 | Using polymer elasticity to scale up the lab characteristics to field application of friction reducers - A method of determining the friction pressure drop gradient of at least one drag-reducing polymer passing through a tubing in an underground well includes determining the pressure drop, velocity and relaxation time of the drag-reducing polymer as it passes through a length of small diameter straight tubing at multiple injection rates in the lab. For each data set, the variables x=(Relaxation Time×Velocity) and y=(Pressure Drop Gradient×Diameter | 02-14-2013 |
Qiuping Qu, Troy, MI US
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20110041803 | Ignition Coil With Ionization And Digital Feedback For An Internal Combustion Engine - Systems and methods for controlling an internal combustion engine include an ignition coil that generates a pre-discharge ionization signal during charging of the ignition coil after reaching a first threshold charge level and prior to spark discharge and a controller that determines an engine operating condition, such as pre-ignition or plug fouling, in response to the pre-discharge ionization signal. The ignition coil may also generate digital feedback and ionization signals used to by the controller for to control ignition coil dwell and repetitive sparking, as well as providing various combustion diagnostics. | 02-24-2011 |
20130206106 | SYSTEM AND METHOD FOR MONITORING AN IGNITION SYSTEM - A system for monitoring and cleaning a spark plug is disclosed. In one example, an amount of carbonaceous soot at the center electrode ceramic of the spark plug is determined in response to a voltage of a sense resistor that is in electrical communication with the spark plug. The system may institute spark plug cleaning after carbonaceous soot is detected so that the possibility of engine misfire may be reduced. | 08-15-2013 |
20130284148 | IGNITION COIL WITH IONIZATION AND DIGITAL FEEDBACK FOR AN INTERNAL COMBUSTION ENGINE - Systems and methods for controlling an internal combustion engine include an ignition coil that generates a pre-discharge ionization signal during charging of the ignition coil after reaching a first threshold charge level and prior to spark discharge and a controller that determines an engine operating condition, such as pre-ignition or plug fouling, in response to the pre-discharge ionization signal. The ignition coil may also generate digital feedback and ionization signals used to by the controller to control ignition coil dwell and repetitive sparking, as well as providing various combustion diagnostics. | 10-31-2013 |
20140102412 | SYSTEM AND METHOD FOR DELIVERING SPARK TO AN ENGINE - A system and method for delivering spark to an engine is disclosed. In one example, a single conductor carries a spark signal that is indicative of a desired spark advance for a plurality of ignition coils. The system and method may reduce wiring complexity for spark plugs that are supplied energy via two ignition coils. | 04-17-2014 |
20140109568 | METHOD FOR PURGING CONDENSATE FROM A CHARGE AIR COOLER - Methods and systems are provided for performing a pro-active condensate clean-out of a charge air cooler. In response to condensate in a charge air cooler and engine operating conditions, airflow is increased to the intake manifold, purging condensate from the cooler. Engine actuators may also be adjusted to maintain torque demand during the clean-out procedure. | 04-24-2014 |
20140360476 | DUAL COIL IGNITION SYSTEM - A dual coil ignition system is provided. The dual coil ignition system includes a first inductive ignition coil including a first primary winding and a first secondary winding, and a second inductive ignition coil including a second primary winding and a second secondary winding, the second secondary winding connected in series to the first secondary winding. The dual coil ignition system further includes a diode network including a first diode and a second diode connected between the first secondary winding and the second secondary winding. | 12-11-2014 |
Ql Qu, Spring, TX US
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20100197966 | METHODS OF MAKING POLYBORONIC COMPOUNDS AND COMPOSITIONS RELATED THERETO - Polyboronic compounds and methods of making them are provided. The polyboronic compounds are useful as crosslinking agents. The polyboronic compounds are produced by contacting a polymeric amine with a trialkylborate in the presence of a solvent so that the resulting molecule has more than one B—N bond. | 08-05-2010 |
Rongda Qu, Cary, NC US
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20090106854 | Polyubiquitin Rubi3 Promoter and 5' Regulatory Sequences - The present invention provides novel expression control elements and methods for expressing a heterologous nucleotide sequence of interest in plants. Isolated nucleic acids, expression cassettes and vectors comprising the expression control elements are provided. Also provided are transformed plants, plant tissues, plant cells, plant seed, and the like, comprising the isolated nucleic acids, expression cassettes and vectors of the invention. Further provided are methods of expressing a heterologous nucleotide sequence of interest in a plant, plant tissue, plant cell, and the like. | 04-23-2009 |
20110138495 | Methods and Compositions for Expressing Proteins In Plants - Methods and compositions comprising an expression construct and a suppressor of posttranscriptional gene silencing construct are described. The expression construct and suppressor construct may comprise a viral amplicon. The expression construct may comprise fusing the target gene to the 3′ and/or 5′ end of a gene encoding a transit peptide sequence or a signaling peptide sequences. The transit or signal peptide sequence directs the target gene product to a subcellular location. Methods comprise the production of several heterologous proteins in a single plant. The invention comprises methods for plant production and protein harvest that will yield useful amounts of the desired protein(s) in as little as one to two weeks after the initiation of the production cycle. Methods for the inoculation of recipient plants by spraying with recombinant | 06-09-2011 |
Rongda Qu, Holly Springs, NC US
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20130091606 | Methods and compositions for enhanced Agrobacterium-mediated transformation Efficiency - The present invention relates to a method of | 04-11-2013 |
20140246036 | TRANSCRIPTION FACTORS THAT REGULATE NICOTINE BIOSYNTHESIS IN TOBACCO - The present invention provides nucleic acids encoding transcription factors and methods of using these nucleic acids to modulate nicotine production in plants and to produce plants having modulated nicotine production. | 09-04-2014 |
Ronghai Qu, Clifton Park, NY US
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20080315698 | MOTOR APPARATUS AND METHOD - An apparatus includes a first motor and a second motor. The first motor includes a first rotor configured to provide mechanical power to a vehicle, and a first plurality of stator coils having a core and coupled to the first rotor. The second motor includes a second rotor configured to provide mechanical power to the vehicle, and a second plurality of stator coils sharing the same core as the first plurality of stator coils and coupled to the second rotor. | 12-25-2008 |
20090085354 | SYSTEM AND METHOD FOR CONTROLLING TORQUE RIPPLES IN SYNCHRONOUS MACHINES - A system for controlling torque ripple in a permanent magnet synchronous machine includes a power converter configured to be coupled to the permanent magnet synchronous machine and to receive converter control signals and a system controller coupled to the power converter. The system controller includes a fundamental current controller configured for providing fundamental voltage commands, a harmonic current controller configured for using harmonic current commands, current feedback signals from the permanent magnet machine, and fundamental current commands in combination with positive and negative sequence regulators to obtain harmonic voltage commands, and summation elements configured for adding the fundamental voltage commands and the harmonic voltage commands to obtain the converter control signals. | 04-02-2009 |
20090098003 | MULTIPHASE SCREW PUMP - A twin screw pump includes a pair of rotors disposed inside a casing having an inlet and an outlet. Each rotor includes a set of threads disposed on a portion of an outer surface of a shaft. A first bearing is coupled at a first end of the shaft and a second bearing is coupled at a second end of the shaft. The first and second bearings are not separated by one or more seals. The first and second bearings are configured for being lubricated by the liquid medium of the process fluid when the twin screw pump is in an operational mode. | 04-16-2009 |
20090140526 | STATOR AND STATOR TOOTH MODULES FOR ELECTRICAL MACHINES - An electrical machine comprising a rotor and a stator is provided. The stator includes a plurality of stator tooth modules configured for radial magnetic flux flow. The stator tooth modules include at least one end plate, and the end plates have extensions for mounting onto a stator frame. The stator is concentrically disposed in relation to the rotor of the electrical machine. | 06-04-2009 |
20090232664 | Permanent magnet motor for subsea pump drive - A subsea pump drive employs a permanent magnet (PM) motor to drive a subsea pump. The PM motor rotor in one embodiment is canned with a non-magnetic material such as inconel that can provide a desired level of corrosion protection. The PM motor provides a subsea pump drive that is smaller and more efficient, having a high power factor than a subsea pump drive utilizing a conventional induction motor. The PM motor subsea pump drive eliminates the necessity for a topside storage tank and associated fluid transfer lines when the motor rotor is cooled with processed fluid. | 09-17-2009 |
20090309442 | HIGH TORQUE DENSITY ELECTRICAL MACHINE - An electrical machine is provided. The electrical machine includes a rotor comprising an inner rotor having a plurality of inner rotor poles and an outer rotor having a plurality of outer rotor poles. The electrical machine further comprises a stator configured to modulate a magnetic flux and to transmit torque to inner rotor and the outer rotor, the stator comprising a stator core interposed concentrically between the inner rotor and the outer rotor; a multiple of stator windings disposed in a plurality of stator slots, the stator windings configured to form a multiple of stator poles. The stator further comprises a plurality of stator teeth interposed between the plurality of stator slots, wherein an arithmetic sum or difference of twice number of stator teeth and a number of the stator poles equals a number of rotor poles. | 12-17-2009 |
20110018281 | SYSTEM AND METHOD FOR CONTROLLING TORQUE RIPPLES IN SYNCHRONOUS MACHINES - A system for controlling torque ripple in a permanent magnet synchronous machine includes a power converter configured to be coupled to the permanent magnet synchronous machine and to receive converter control signals and a system controller coupled to the power converter. The system controller includes a fundamental current controller configured for providing fundamental voltage commands, a harmonic current controller configured for using harmonic current commands, current feedback signals from the permanent magnet machine, and fundamental current commands in combination with positive and negative sequence regulators to obtain harmonic voltage commands, and summation elements configured for adding the fundamental voltage commands and the harmonic voltage commands to obtain the converter control signals. | 01-27-2011 |
20110133469 | WIND TURBINE DRIVETRAIN SYSTEM - A wind turbine is provided having a drivetrain with a gearbox and a gearbox housing, at least one gear stage and an output shaft coupled within the housing. The gear stage exerts an axial thrust force on the output shaft during operation of the wind turbine. A generator includes a generator housing and an input shaft connected to the output shaft of the gearbox. The generator includes a rotor and a stator coupled to the generator housing. The rotor is coupled to the input shaft such that the rotor is positioned radially inward from the stator. At least one bearing is shared between the gearbox output shaft and the generator input shaft, and this bearing carries a portion of the axial thrust force. The generator is skewed to exert an opposing axial thrust force on the input shaft, so that the axial thrust force carried by the bearing is reduced. | 06-09-2011 |
20140361653 | HIGH TORQUE DENSITY ELECTRICAL MACHINE - An electrical machine includes a rotor comprising a rotor core and a plurality of permanent magnets embedded radially within the rotor core to form a plurality of rotor poles. The electrical machine further includes a stator comprising a stator core disposed concentrically outside the rotor and including a plurality of stator teeth defining a plurality of stator slots there between. An arithmetic sum or difference of twice the number of stator teeth and the number of the stator poles equals the number of rotor poles. | 12-11-2014 |
Ronghai Qu US
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20100244446 | GAS TURBINE ENGINE ASSEMBLY INCLUDING DUAL SIDED/ DUAL SHAFT ELECTRICAL MACHINE - A gas turbine engine assembly includes an electromagnetic machine for extracting power from the turbine engine. The electromagnetic machine includes an outer rotor and an inner rotor rotatably supported adjacent to a stator disposed between the inner and outer rotors. The stator has an inner set of windings disposed on an inner surface adjacent to the inner rotor, and an outer set of windings on an outer surface of the stator adjacent to the outer rotor. The inner stator windings form a set of multiple-phase windings, and the outer stator windings form a set of multiple-phase windings. | 09-30-2010 |
Shankang Qu, Fair Lawn, NJ US
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20090248315 | System and Method for Determining Clinical Equivalence of Test Methods - A system, method and computer readable medium of instructions are provided which are useful for determining whether an evaluation testing method or device is clinically equivalent to a reference testing method or device. The report can include a modified mean difference plot, a variability chart, confidence intervals for bias and a plot of the intervals. A graphical user interface is provided to allow data associated with the reference and evaluation methods or devices to be identified. A level of variance in the reference method is determined. An observed bias between the evaluation methods or devices and the reference methods or devices is calculated. A confidence interval for the bias is calculated. The biases between the evaluation methods or devices and reference method or device is compared relative to the level of variance in the reference method, and a report is generated including a conclusion about whether the evaluation methods or devices are clinically equivalent to the reference method or device. | 10-01-2009 |
Shimian Qu, Brentwood, TN US
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20080206130 | IN VIVO PANNING FOR LIGANDS TO RADIATION-INDUCED MOLECULES - A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor. | 08-28-2008 |
20110213293 | LIGANDS TO RADIATION-INDUCED MOLECULES - A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands. | 09-01-2011 |
20130251628 | LIGANDS TO RADIATION-INDUCED MOLECULES - A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands. | 09-26-2013 |
20140369929 | LIGANDS TO RADIATION-INDUCED MOLECULES - A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands. | 12-18-2014 |
Susan Yun Qu, Auburndale, MA US
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20090023629 | COMPOSITIONS COMPRISING POLYCATION-COMPLEXED PROTEIN CRYSTALS AND METHODS OF TREATMENT USING THEM - The present invention relates to compositions comprising polycation-complexed protein crystals and hyaluronic acid. Advantageously, the compositions of this invention are stable, long-acting and avoid local reactions at the injection site. Compositions according to this invention include sustained-release human growth hormone compositions. Such compositions are useful for treating a subject having a disorder associated with human growth hormone deficiency or that is ameliorated by human growth hormone therapy. | 01-22-2009 |
Wei Feng Qu US
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20130341763 | BONDED SUBSTRATE AND MANUFACTURING METHOD THEREOF - The invention provides a method for manufacturing a bonded substrate by bonding a base substrate to a bond substrate through an insulator film, including: a porous layer forming step of partially forming a porous layer or forming a porous layer whose thickness partially varies on a bonding surface of the base substrate; an insulator film forming step of changing the porous layer into the insulator film, and thereby forming the insulator film whose thickness partially varies on the bonding surface of the base substrate; a bonding step of bonding the base substrate to the bond substrate through the insulator film; and a film thickness reducing step of reducing a film thickness of the bonded bond substrate to form a thin-film layer. As a result, there is provided the method for manufacturing a bonded substrate that enables obtaining an insulator film whose thickness partially varies with use of a simple method. | 12-26-2013 |
Weiguo Qu, State College, PA US
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20130026409 | Composite ionic conducting electrolytes - Ionically conducting, redox active additive composite electrolytes are disclosed. The electrolytes include an ionically conductive component and a redox active additive. The ionically conductive component may be an ionically conductive material such as an ionically conductive polymer, ionically conducting glass-ceramic, ionically conductive ceramic, and mixtures thereof. Electrical energy storage devices that employ the ionically conducting, redox active additive composite electrolytes also are disclosed | 01-31-2013 |
Weilin Qu, Honolulu, HI US
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20090139693 | TWO PHASE MICRO-CHANNEL HEAT SINK - A method and system for providing a heat sink are described. The heat sink includes at least one inlet, at least one outlet, a plurality of flow micro-channels, and at least one cross-connect channel. The plurality of flow micro-channels are defined by a plurality of channels walls, connect the inlet(s) with the outlet(s) and accommodate a flow of coolant between the at least one inlet and the at least one outlet. The at least one cross-connect channel is configured to connect at least a portion of the plurality of flow micro-channels. The cross-connect channel(s) also at least partially equilibrate a pressure field for boiling of the coolant across the portion of the plurality of flow micro-channels. | 06-04-2009 |
20090139701 | TWO-PHASE CROSS-CONNECTED MICRO-CHANNEL HEAT SINK - An improved two-phase micro-channel heat sink has a plurality of flow micro-channels extending in parallel in a longitudinal direction for accommodating a flow of liquid coolant therein, and a plurality of cross-connected micro-channels extending in parallel in a transverse direction formed at regular intervals along the longitudinal direction for cross-connecting with the flow micro-channels. The cross-connected micro-channels enable a uniform pressure field to be maintained for two-phase flow boiling of liquid coolant in the heat sink. In a preferred embodiment, the heat sink contains flow micro-channels with width of 100 μm, wall thickness of 100 μm, and height of 600 μm, and cross-connected micro-channels of similar width and height cut at 1 mm intervals along the flow direction. | 06-04-2009 |
Wen Qu, Memphis, TN US
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20090239891 | Sustained Release Dosage Forms of Analgesic Medications - Parenteral extravascular administration of a composition containing an analgesic medication of low water solubility that is dissolved, suspended, or emulsified in a solvent system results in the deposition of the analgesic medication at the site of administration and provides a controlled release of the analgesic medication from the site and a prolonged analgesia that may persist for several days following administration. | 09-24-2009 |
20100099696 | Tamper resistant oral dosage forms containing an embolizing agent - Oral dosage form containing a therapeutically effective amount of a drug susceptible to abuse and an effective amount of an embolizing agent which causes the production of a solid or semi-solid embolus or blockage after tampering. | 04-22-2010 |
Wenchao Qu, Philadelphia, PA US
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20110158907 | DIPHENYL-HETEROARYL DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES - This invention relates to a method of imaging amyloid deposits and to diphenyl-heteroaryl compounds, and methods of making radiolabeled diphenyl-heteroaryl compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits. | 06-30-2011 |
Wenchao Qu, Ardmore, PA US
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20120288444 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS OF THEIR PREPARATION AND USE - The present invention is directed single diasteromers of 4-fluoroglutamine having a diastereomeric excess of at least 80%. Methods of preparing the single diastereomers are also described, as well as methods of using the single diastereomers of radiolabeled 4-fluoroglutamine as imaging agent is also described. | 11-15-2012 |
Xiaoling Qu, Beachwood, OH US
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20120070847 | Method For Detecting And Purifying Pancreatic Beta Cells - The invention is based, in part, on the discovery that a polypeptide, referred to herein as Betacam, is selectively expressed on the surface of pancreatic islet cells, Thus, in one aspect, the invention is directed to compositions comprising Betacam or that can be used to detect Betacam. In another aspect, the invention provides methods of detecting (e.g., non-invasively) pancreatic beta cells from a mammalian cell source. Another aspect of the invention is directed to cellular purification of pancreatic beta cells from a heterogeneous cell source of multiple kinds. In another aspect, the invention provides methods of identifying agents that modulate activity of Betacam-In yet another aspect, the invention provides for improved treatment and diagnosis of diabetes. | 03-22-2012 |
Xiaoyan Qu, Mason, OH US
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20090178145 | Methods and targets for identifying compounds for regulating angiogenesis - The present invention provides methods for identifying genes and proteins that may regulate angiogenesis. The genes identified may be used as markers for the disease onset and progression and to measure efficacy of a therapeutic. The present invention also provides methods to screen agents that are capable of regulating angiogenesis. The present invention also provides methods of identifying therapeutic compounds that may treat various disorders by regulating the expression and activity of genes and proteins identified. | 07-09-2009 |
Xin Qu, East Brunswick, NJ US
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20100151029 | Anti-infectious hydrogel compositions - The present invention provides a hydrogel composition capable of preventing the intrusion of micro-organisms into body cavities or body openings of mammals comprising of a poly(N-vinyl lactam), a polysaccharide and water. | 06-17-2010 |
Yi Qu, Troy, MI US
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20130069377 | Bumper Beam with Load Transferring Section - A motor vehicle includes a frame with energy-absorbing zones at outboard corners of the vehicle and a bumper beam mounted to the energy-absorbing zones to transfer force to at least one of the energy-absorbing zones during a collision. The bumper beam includes a center section extending generally laterally across the vehicle between the energy-absorbing zones, and left and right load transfer sections attached to outboard ends of the center section. Each load transfer section extends outboard and rearward such that the free end of each load transfer section is disposed outboard of the frame adjacent a rear end of its respective energy-absorbing zone. In a small-overlap collision, the load transfer section on the side of the impact bends rearward as the energy-absorbing zone deforms, and the free end of the load transfer section contacts the frame to transfer crash loads to the frame. | 03-21-2013 |
Yi Qu, City Of Coppell, TX US
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20120303165 | CONTROL SYSTEM AND METHOD FOR BOTH ENERGY SAVING AND COMFORT CONTROL IN AN AIR CONDITIONING SYSTEM - A control system and method for controlling both temperature and humidity in an air conditioning system having a variable-speed compressor and a variable-speed indoor blower. In one embodiment, the control system includes: (1) a temperature control loop in which a target speed of the compressor is determined based on sensed and setpoint temperatures and (2) a humidity control loop, located in the temperature control loop, in which a target speed of the indoor blower is determined based on sensed and setpoint humidities, the target speed of the compressor employable to control the compressor and the target speed of the indoor blower employable to control the indoor blower of the air conditioning system. | 11-29-2012 |
Yi Qu, Coppell, TX US
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20130160474 | METHOD TO CONTROL ELECTRONIC EXPANSION VALVE - A vapor compression refrigeration cycle system includes a compressor and an electronic expansion valve connected between first and second refrigerant ports of a compressor. An expansion valve controller is configured to control a flow of refrigerant through the expansion valve in response to a superheat temperature of the refrigerant. The controller is configured to execute a first control algorithm until a local maximum of the superheat temperature occurs, and then to execute a second control algorithm. | 06-27-2013 |
20140109605 | Pressure Regulation of an Air Conditioner - In various implementations, air conditioners may include a high pressure portion and a low pressure portion. A bypass line may divert a portion of the refrigerant from the high pressure portion to the low pressure portion to reduce the pressure of at least a part of the high pressure portion. The bypass line may be opened automatically. | 04-24-2014 |
20140150477 | Defrost Control Using Fan Data - In various implementations, frost in a vapor compression system may be controlled. A property of a fan may be determined. A determination may be made whether a frost event and/or a nonfrost event has occurred based at least partially on the determined fan property. | 06-05-2014 |
20140150479 | Secondary Defrost for Heat Pumps - Frost may accumulate on a heat pump. In various implementations, a primary defrost operation and/or a secondary defrost operation may be utilized to remove at least a portion of the frost from the heat pump. | 06-05-2014 |
20140165612 | CONTROLLING AIR CONDITIONER MODES - In various implementations, a request for operation of an air conditioner may be received. The air conditioner may include a cooling mode and/or a dehumidifying mode. In some implementations, a compressor speed for a compressor of the air conditioner may be determined, and which mode(s) of the air conditioner to allow may be determined based at least partially on the determined compressor speed. | 06-19-2014 |
20150047375 | DEFROST OPERATION MANAGEMENT IN HEAT PUMPS - In various implementations, a heat pump may include heating operations and defrost operations. The heat pump may monitor cycle time(s) for one or more of the operations. Defrost operation(s) in the heat pump may be automatically adjusted based at least partially on cycle times. | 02-19-2015 |
Yong Qu, Sammamish, WA US
Patent application number | Description | Published |
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20120297360 | DYNAMIC CODE GENERATION AND MEMORY MANAGEMENT FOR COMPONENT OBJECT MODEL DATA CONSTRUCTS - Dynamic code generation and memory management techniques are provided for component object model (COM) objects with corresponding representations in script code and native code. A browser component can receive script code including the code representing the COM object and a marshaling component is provided that marshals, based on a request for native code representing the COM object, the code representing the COM object to the native code based on a pre-constructed intermediate data structure. The pre-constructed intermediate data structure, such as a virtual table, is pre-constructed based on a dynamic type representation associated with a prototype of the COM object and cached for re-use by the marshaling component. Other embodiments provide finalizer support for memory management of COM objects having script and native world representations including an implementation of a two-phase commit protocol that enables efficient and conservative recycling of objects and associated memory. | 11-22-2012 |
20120304044 | INTERFACE DEFINITION LANGUAGE EXTENSIONS - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 11-29-2012 |
20120304150 | BINDING BETWEEN A LAYOUT ENGINE AND A SCRIPTING ENGINE - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 11-29-2012 |
20120304203 | MEMORY MODEL FOR A LAYOUT ENGINE AND SCRIPTING ENGINE - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 11-29-2012 |
20120304303 | SECURITY MODEL FOR A LAYOUT ENGINE AND SCRIPTING ENGINE - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 11-29-2012 |
20130042255 | Memory Model for a Layout Engine and Scripting Engine - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 02-14-2013 |
20130047064 | Interface Definition Language Extensions - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 02-21-2013 |
20130047258 | Security Model for a Layout Engine and Scripting Engine - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 02-21-2013 |
20130132930 | CAPTURING TELEMETRY DATA BY DYNAMIC LANGUAGE ENGINE - At least one embodiment described herein relates to the selective capturing of script code stacks associated with exceptions thrown by script code. For unhandled exceptions, the script engine 1) captures the script code stack in a host-accessible manner in which a host that hosts the script engine may access the captured script code stack, 2) completes unwinding of the script stack, and 3) reports the captured script code stack to a host that hosts the script engine. For at least one of the handled exceptions thrown by the script code for which the script code itself handles the exception, the script code stack is not captured in the host-accessible manner. Also, the call stack property of an error object is populated at throw time, rather than creation time. | 05-23-2013 |
20140365862 | Memory Model for a Layout Engine and Scripting Engine - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 12-11-2014 |
20150026661 | BINDING BETWEEN A LAYOUT ENGINE AND A SCRIPTING ENGINE - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 01-22-2015 |
20150058714 | Memory Model for a Layout Engine and Scripting Engine - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 02-26-2015 |
20150058924 | Security Model for a Layout Engine and Scripting Engine - Various embodiments provide an interface between a Web browser's layout engine and a scripting engine. The interface enables objects from the layout engine to be recognized by a memory manager in the scripting engine and interact in a streamlined, efficient manner. In accordance with one or more embodiments, the interface allows browser layout engine objects to be created as objects that are native to the scripting engine. Alternately or additionally, in some embodiments, the native objects are further configured to proxy functionality between the layout engine and the scripting engine. | 02-26-2015 |
Yujiang Qu, Ashburn, VA US
Patent application number | Description | Published |
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20120023545 | SYSTEM AND METHOD FOR PROVIDING A HIGH PERFORMANCE NETWORK CONNECTION SERVICE FOR DISTRIBUTED COMPUTING APPLICATIONS - A system and method are disclosed for providing a high performance network connection service (HPNCS) for distributed computing applications. The HPNCS provides a network abstraction layer to the distributed applications and provides an interface to the underlying high performance on-demand dynamic circuit network (DCN). The HPNCS may relieve performance bottleneck problems encountered by the distributed applications due to the limited available networking bandwidth. The HPNCS may be used by distributed applications that need to access dedicated high performance network connection resources, such as DCN circuits, on an as-needed basis without over consuming expensive network resources. | 01-26-2012 |
Zhican Qu, Birmingham, AL US
Patent application number | Description | Published |
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20080234275 | METHOD FOR TREATING AND PREVENTING ARTHRITIS - Compounds represented by the formula 1: | 09-25-2008 |
20100120745 | ANTI-ANGIOGENIC AGENTS AND METHODS OF USE - The present disclosure relates generally to treating or preventing diseases associated with angiogenesis by administering to a patient certain compounds found to inhibit or substantially reduce angiogenesis. Compounds employed according to the present disclosure exhibit good anti-angiogenic activity as well as demonstrate a prophylactic effect for preventing and substantially reducing angiogenesis. Examples of such compounds include Ritanserin, Amiodarone, Terfenadine, Perphenazine, Bithionol, and Clomipramine. | 05-13-2010 |
20100204338 | ANTI-ANGIOGENIC AGENTS AND METHODS OF USE - The present disclosure relates generally to treating or preventing diseases associated with angiogenesis by administering to a patient certain compounds found to inhibit or substantially reduce angiogenesis. Compounds employed according to the present disclosure exhibit good anti-angiogenic activity as well as demonstrate a prophylactic effect for preventing and substantially reducing angiogenesis. Examples of such compounds include Ritanserin, Amiodarone, Terfenadinc, Perphenazine, Bithionol, and Clomipramine. | 08-12-2010 |
20110301165 | METHOD FOR TREATING AND PREVENTING ARTHRITIS - Compounds represented by the formula 1: | 12-08-2011 |
20130059811 | METHOD FOR TREATING AND PREVENTING ARTHRITIS - Compounds represented by the formula 1: | 03-07-2013 |
20130123240 | METHOD OF USING BIOTHIONOL AND BIOTHIONOL-LIKE COMPOUNDS AS ANTI-ANGIOGENIC AGENTS - The present disclosure relates generally to treating or preventing diseases associated with angiogenesis by administering to a patient certain compounds found to inhibit or substantially reduce angiogenesis. Compounds employed according to the present disclosure exhibit good anti-angiogenic activity as well as demonstrate a prophylactic effect for preventing and substantially reducing angiogenesis. Examples of such compounds include Ritanserin, Amiodarone, Terfenadinc, Perphenazine, Bithionol, and Clomipramine. | 05-16-2013 |
20130288996 | METHOD FOR TREATING AND PREVENTING ARTHRITIS - Compounds represented by the formula 1: | 10-31-2013 |
Zhuqing Qu, Pittsburgh, PA US
Patent application number | Description | Published |
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20110243900 | SOFT TISSUE AND BONE AUGMENTATION AND BULKING UTILIZING MUSCLE-DERIVED PROGENITOR CELLS, COMPOSITIONS AND TREATMENTS THEREOF - The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for dermatological conditions, gastroesophageal reflux, vesico-ureteral reflux, urinary incontinence, fecal incontinence, heart failure, and myocardial infarction. | 10-06-2011 |