Patent application number | Description | Published |
20100122355 | Transgenic Reporter Mouse and Method for Use - A transgenic mammal, including a transgenic mouse, whose genome comprises a transgene, said transgene comprises a neutrophil gelatinase-associated lipocalin (NGAL) promoter gene operably linked to at least one sequence encoding at least one of a fluorescent or bioluminescent protein, wherein the NGAL promoter gene expression in the mouse can be assayed by bioluminescence or fluorescence imaging. | 05-13-2010 |
20110214190 | TRANSGENIC REPORTER MOUSE AND METHOD FOR USE - A transgenic mammal, including a transgenic mouse, whose genome comprises a transgene, said transgene comprises a neutrophil gelatinase-associated lipocalin (NGAL) promoter gene operably linked to at least one sequence encoding at least one of a fluorescent or bioluminescent protein, wherein the NGAL promoter gene expression in the mouse can be assayed by bioluminescence or fluorescence imaging. | 09-01-2011 |
20130217637 | MUTANT NGAL PROTEINS AND USES THEREOF - In one aspect the present invention is directed to mutant NGAL proteins that have the ability to bind to siderophores, such as enterochelin, and to chelate and transport iron, and that are excreted in the urine. Such NGAL mutants, and complexes thereof with siderophores, can be used to clear excess iron from the body, for example in the treatment of iron overload. The NGAL mutants of the invention also have antibacterial activity and can be used in the treatment of bacterial infections, such as those of the urinary tract. | 08-22-2013 |
Patent application number | Description | Published |
20090141643 | IDENTIFICATION OF THE CONFIGURATION TOPOLOGY, EXISTING SWITCHES, AND MISWIRES IN A SWITCHED NETWORK - An exemplary method of identifying configuration topology, existing switches, and miswires in a given network is provided. Given a number of switches, which may be less than the maximum possible for the actual configuration and some ports of which may be miswired, generate a hypothesis for the supported topology of which the existing configuration is a subset. A best fit of the existing switches to the supported number switches of the maximal topology is performed, using formulae for the connections of the maximal supported topology. If supported switches are found missing in the assumed topology, the switch count is increased accordingly, and started over with a new hypothesis. When satisfied with identification, all switch ports are revisited and the connection formulae is used to identify all miswires. | 06-04-2009 |
20140304554 | ENABLING COMMUNICATION OVER CROSS-COUPLED LINKS BETWEEN INDEPENDENTLY MANAGED COMPUTE AND STORAGE NETWORKS - Embodiments relate to providing communication over cross-coupled links between independently managed compute and storage networks. An aspect includes coupling an independently managed local subsystem with an independently managed remote subsystem over cross-coupled links, whereby each subsystem includes compute entities and storage entities. Unique identifiers are assigned to all the compute entities and the storage entities in the local network and the remote network. A determination is then made as to whether each entity is in the local subsystem or the remote subsystem. Accordingly, a global broadcast tree is built to bridge the compute entities in the local subsystem to the storage entities in both the local and remote subsystem. Responsive to an error in a layer of the local subsystem external to a cross-coupled link, the cross-coupled link in the local subsystem is disabled. Accordingly, the remote subsystem may detect that the link has failed. | 10-09-2014 |
Patent application number | Description | Published |
20100071469 | Synthesized synchronous sampling and acceleration enveloping for differential bearing damage signature - A system for detecting differential bearing damages includes a synthesized tachometer that generates a tachometer signal corresponding to the race speed difference of a bearing assembly such that the bearing damage speed difference dependency can be eliminated and the damage features can be enhanced. The system also includes acceleration enveloping in the cycle domain to further enhance the damage signatures. | 03-25-2010 |
20110040470 | Starter Control Valve Failure Prediction Machine To Predict and Trend Starter Control Valve Failures In Gas Turbine Engines Using A Starter Control Valve Health Prognostic, Program Product and Related Methods - Starter control valve failure prediction machines, systems, program products, and computer implemented methods to predict and trend starter control valve failures in gas turbine engines using a starter control valve health prognostic and to make predictions of starter control valve failures, are provided. A computer implemented method according to an embodiment of the present invention can include the steps of generating a continuous starter control valve deterioration trend function responsive to a plurality of health indices derived from gas turbine engine startup data downloaded from gas turbine engine sensors for a plurality of startups and analyzing the continuous starter control valve deterioration trend function to identify potential starter control valve failure points where the points on the starter control valve deterioration trend function correlate to a starter control valve health prognostic responsive to historic gas turbine engine startup data downloaded from gas turbine engine sensors. | 02-17-2011 |
20130133306 | Starter Control Valve Prediction System to Predict and Trend Starter Control Valve Failures in Gas Turbine Engines Using a Starter Control Valve Health Prognostic, Computer Readable Medium and Related Methods - Starter control valve failure prediction machines, systems, computer readable media, program products, and computer implemented methods to predict and trend starter control valve failures in gas turbine engines using a starter control valve health prognostic and to make predictions of starter control valve failures, are provided. A computer implemented method according to an embodiment of the present invention can include the steps of generating a continuous starter control valve deterioration trend function responsive to a plurality of health indices derived from gas turbine engine startup data downloaded from gas turbine engine sensors for a plurality of startups and analyzing the continuous starter control valve deterioration trend function to identify potential starter control valve failure points where the points on the starter control valve deterioration trend function correlate to a starter control valve health prognostic responsive to historic gas turbine engine startup data downloaded from gas turbine engine sensors. | 05-30-2013 |
20140188777 | METHODS AND SYSTEMS FOR IDENTIFYING A PRECURSOR TO A FAILURE OF A COMPONENT IN A PHYSICAL SYSTEM - A computer-implemented system for identifying a precursor to a failure of a particular type of component in a physical system is provided. The physical system includes sensors coupled to the physical system. The computer-implemented system includes a computing device, a database, a processor, and a memory device. The memory device includes historical data including sensor measurements. When instructions are executed by the processor, the processor receives the historical data from the memory device. The processor generates a predictive model. The predictive model uses, as inputs, sensor measurements in the historical data. The predictive model is able to differentiate between sensor measurements taken before the repair event and those taken after the repair event without a time of the repair event being an input to the predictive model. The processor designates at least one sensor measurements used as inputs to the predictive model as precursors to the failure of the component. | 07-03-2014 |
Patent application number | Description | Published |
20090248598 | Hardware acceleration of DNA codeword searching - An apparatus for a hybrid architecture that consists of a general purpose microprocessor and a hardware accelerator for accelerating the discovery of DNA reverse complement, edit distance codes. Two embodiments are implemented and evaluated, including a code generator that uses a genetic algorithm (GA) to produce nearly locally optimal codes in a few minutes, and a code extender that uses exhaustive search to produce locally optimum codes in about 1.5 hours for the case of length 16 codes. Experimental results demonstrate that the GA embodiment can find ˜99% of the words in locally optimum libraries, and that the hybrid architecture embodiment provides more than 1000 times speed-up compared to a software only implementation. | 10-01-2009 |
20090325820 | Hardware acceleration for thermodynamically constrained DNA code generation - An apparatus that accelerates the determination of NN free energy of binding estimates for a large number of DNA oligomers using reconfigurable hardware and applies it to the design of high quality DNA code word libraries. The invention provides a reconfigurable hardware accelerator and method for implementing a nearest-neighbor based free energy calculation. The invention further provides a method to produce the maximum weight of the 2-stem common subsequence of two DNA oligonucleotides. In practice, the present invention comprises a general purpose microprocessor or computer, a hardware accelerator, and a software program. | 12-31-2009 |
20110224916 | Fitness determination for DNA codeword searching - An apparatus for a hybrid architecture that consists of a general purpose microprocessor and a hardware accelerator for accelerating the discovery of DNA reverse complement, edit distance codes. Two embodiments are implemented and evaluated, including a code generator that uses a genetic algorithm (GA) to produce nearly locally optimal codes in a few minutes, and a code extender that uses exhaustive search to produce locally optimum codes in about 1.5 hours for the case of length 16 codes. Experimental results demonstrate that the GA embodiment can find ˜99% of the words in locally optimum libraries, and that the hybrid architecture embodiment provides more than 1000 times speed-up compared to a software only implementation. | 09-15-2011 |
20110225109 | Hardware acceleration of DNA codeword searching and fitness determination - An apparatus for a hybrid architecture that consists of a general purpose microprocessor and a hardware accelerator for accelerating the discovery of DNA reverse complement, edit distance codes. Two embodiments are implemented and evaluated, including a code generator that uses a genetic algorithm (GA) to produce nearly locally optimal codes in a few minutes, and a code extender that uses exhaustive search to produce locally optimum codes in about 1.5 hours for the case of length 16 codes. Experimental results demonstrate that the GA embodiment can find ˜99% of the words in locally optimum libraries, and that the hybrid architecture embodiment provides more than 1000 times speed-up compared to a software only implementation. | 09-15-2011 |
20110225110 | Software control of hardware accelerated DNA codeword searching - An apparatus for a hybrid architecture that consists of a general purpose microprocessor and a hardware accelerator for accelerating the discovery of DNA reverse complement, edit distance codes. Two embodiments are implemented and evaluated, including a code generator that uses a genetic algorithm (GA) to produce nearly locally optimal codes in a few minutes, and a code extender that uses exhaustive search to produce locally optimum codes in about 1.5 hours for the case of length 16 codes. Experimental results demonstrate that the GA embodiment can find ˜99% of the words in locally optimum libraries, and that the hybrid architecture embodiment provides more than 1000 times speed-up compared to a software only implementation. | 09-15-2011 |
20120296857 | Hardware acceleration of DNA codeword searching and fitness determination employing a code extender - An apparatus for a hybrid architecture that consists of a general purpose microprocessor and a hardware accelerator for accelerating the discovery of DNA reverse complement edit distance codes. An embodiment is implemented and evaluated, including a code extender that uses exhaustive search to produce locally optimum codes in about 1.5 hours for the case of length 16 codes. | 11-22-2012 |
Patent application number | Description | Published |
20100050607 | System and method for controlling exhaust stream temperature - Systems and methods are provided for controlling an exhaust stream temperature at a point along an exhaust system. The exhaust system can include an oxidation catalyst, a particulate filter having an outlet, and a fuel injector for injecting fuel into an exhaust stream at a location upstream from the outlet. An adaptive control can be provided to model a portion of the exhaust system. A fuel injection flow rate at which fuel is injected into the exhaust stream by the fuel injector can be calculated based on the adaptive control model. An operation of the fuel injector can be controlled based on the calculated fuel injection flow rate, to control the exhaust stream temperature at point along the exhaust system. A condition of the exhaust stream can also monitored and an error in the adaptive control model can be determined based on the monitored condition. The adaptive control model can also be changed to reduce the error. | 03-04-2010 |
20100300070 | Systems And Methods For Controlling Temperature And Total Hydrocarbon Slip - Systems and methods for controlling temperature and total hydrocarbon slip in an exhaust system are provided. Control systems can comprise an oxidation catalyst, a particulate filter, a fuel injector, and a processor for controlling a fuel injection based on an oxidation catalyst model. Example system includes a virtual sensor comprising a controller for calculating and providing the total hydrocarbon slip to subsystems for after-treatment management based on modeling the oxidation catalyst. Example methods for controlling the temperature and the total hydrocarbon slip in an exhaust system include the steps of providing an oxidation catalyst model, monitoring a condition of the exhaust system, calculating a hydrocarbon fuel injection flow rate and controlling a fuel injection. The example methods further include the steps of determining an error in the oxidation catalyst model based on the monitored condition and changing the oxidation catalyst model to reduce the error. | 12-02-2010 |
20110121477 | Methods Of Operating An Extrusion Apparatus - Methods of operating an extrusion apparatus are provided for extruding ceramic or ceramic-forming material. The extrusion apparatus includes an extrusion die mounted with respect to a barrel. At least one screw is rotatably mounted within the barrel, and a feeder is configured to introduce a batch material to the screw. Example methods can adjust at least one of a rotational rate of the screw to an initial rotational rate or a feed rate of the feeder to an initial feed rate when based on a changed operating condition and/or when the batch material reaches the extrusion die. At least one of the rotational rate of the screw or the feed rate of the feeder can then be increased during a transient state until a steady state is reached. | 05-26-2011 |
Patent application number | Description | Published |
20130037111 | Process for Preparation of Elemental Chalcogen Solutions and Method of Employing Said Solutions in Preparation of Kesterite Films - Techniques for preparing chalcogen-containing solutions using an environmentally benign borane-based reducing agent and solvents under ambient conditions, as well as application of these solutions in a liquid-based method for deposition of inorganic films having copper (Cu), zinc (Zn), tin (Sn), and at least one of sulfur (S) and selenium (Se) are provided. In one aspect, a method for preparing a chalcogen-containing solution is provided. The method includes the following steps. At least one chalcogen element, a reducing agent and a liquid medium are contacted under conditions sufficient to produce a homogenous solution. The reducing agent (i) contains both boron and hydrogen, (ii) is substantially carbon free and (iii) is substantially metal free. | 02-14-2013 |
20130045383 | ARRAY OF TITANIUM DIOXIDE NANOSTRUCTURES FOR SOLAR ENERGY UTILIZATION - An array of titanium dioxide nanostructures for solar energy utilization includes a plurality of nanotubes, each nanotube including an outer layer coaxial with an inner layer, where the inner layer comprises p-type titanium dioxide and the outer layer comprises n-type titanium dioxide. An interface between the inner layer and the outer layer defines a p-n junction. | 02-21-2013 |
20130312831 | Techniques for Forming a Chalcogenide Thin Film Using Additive to a Liquid-Based Chalcogenide Precursor - Techniques for enhancing energy conversion efficiency in chalcogenide-based photovoltaic devices by improved grain structure and film morphology through addition of urea into a liquid-based precursor are provided. In one aspect, a method of forming a chalcogenide film includes the following steps. Metal chalcogenides are contacted in a liquid medium to form a solution or a dispersion, wherein the metal chalcogenides include a Cu chalcogenide, an M1 and an M2 chalcogenide, and wherein M1 and M2 each include an element selected from the group consisting of: Ag, Mn, Mg, Fe, Co, Cd, Ni, Cr, Zn, Sn, In, Ga, Al, and Ge. At least one organic additive is contacted with the metal chalcogenides in the liquid medium. The solution or the dispersion is deposited onto a substrate to form a layer. The layer is annealed at a temperature, pressure and for a duration sufficient to form the chalcogenide film. | 11-28-2013 |
20130316519 | Techniques for Forming a Chalcogenide Thin Film Using Additive to a Liquid-Based Chalcogenide Precursor - Techniques for enhancing energy conversion efficiency in chalcogenide-based photovoltaic devices by improved grain structure and film morphology through addition of urea into a liquid-based precursor are provided. In one aspect, a method of forming a chalcogenide film includes the following steps. Metal chalcogenides are contacted in a liquid medium to form a solution or a dispersion, wherein the metal chalcogenides include a Cu chalcogenide, an M1 and an M2 chalcogenide, and wherein M1 and M2 each include an element selected from the group consisting of: Ag, Mn, Mg, Fe, Co, Cd, Ni, Cr, Zn, Sn, In, Ga, Al, and Ge. At least one organic additive is contacted with the metal chalcogenides in the liquid medium. The solution or the dispersion is deposited onto a substrate to form a layer. The layer is annealed at a temperature, pressure and for a duration sufficient to form the chalcogenide film. | 11-28-2013 |