Patent application number | Description | Published |
20100280352 | Method and System for Multi-Component Heart and Aorta Modeling for Decision Support in Cardiac Disease - A method and system for generating a patient specific anatomical heart model is disclosed. Volumetric image data, such as computed tomography (CT), echocardiography, or magnetic resonance (MR) image data of a patient's cardiac region is received. Individual models for multiple heart components, such as the left ventricle (LV) endocardium, LV epicardium, right ventricle (RV), left atrium (LA), right atrium (RA), mitral valve, aortic valve, aorta, and pulmonary trunk, are estimated in said volumetric cardiac image data. A multi-component patient specific anatomical heart model is generated by integrating the individual models for each of the heart components. Fluid Structure Interaction (FSI) simulations are performed on the patient specific anatomical model, and patient specific clinical parameters are extracted based on the patient specific heart model and the FSI simulations. Disease progression modeling and risk stratification are performed based on the patient specific clinical parameters. | 11-04-2010 |
20110060576 | Method and System for Computational Modeling of the Aorta and Heart - A method and system for generating a patient specific anatomical heart model is disclosed. A sequence of volumetric image data, such as computed tomography (CT), echocardiography, or magnetic resonance (MR) image data of a patient's cardiac region is received. A multi-component patient specific 4D geometric model of the heart and aorta estimated from the sequence of volumetric cardiac imaging data. A patient specific 4D computational model based on one or more of personalized geometry, material properties, fluid boundary conditions, and flow velocity measurements in the 4D geometric model is generated. Patient specific material properties of the aortic wall are estimated using the 4D geometrical model and the 4D computational model. Fluid Structure Interaction (FSI) simulations are performed using the 4D computational model and estimated material properties of the aortic wall, and patient specific clinical parameters are extracted based on the FSI simulations. Disease progression modeling and risk stratification are performed based on the patient specific clinical parameters. | 03-10-2011 |
20120022843 | Method and System for Comprehensive Patient-Specific Modeling of the Heart - A method and system for patient-specific modeling of the whole heart anatomy, dynamics, hemodynamics, and fluid structure interaction from 4D medical image data is disclosed. The anatomy and dynamics of the heart are determined by estimating patient-specific parameters of a physiological model of the heart from the 4D medical image data for a patient. The patient-specific anatomy and dynamics are used as input to a 3D Navier-Stokes solver that derives realistic hemodynamics, constrained by the local anatomy, along the entire heart cycle. Fluid structure interactions are determined iteratively over the heart cycle by simulating the blood flow at a given time step and calculating the deformation of the heart structure based on the simulated blood flow, such that the deformation of the heart structure is used in the simulation of the blood flow at the next time step. The comprehensive patient-specific model of the heart representing anatomy, dynamics, hemodynamics, and fluid structure interaction can be used for non-invasive assessment and diagnosis of the heart, as well as virtual therapy planning and cardiovascular disease management. Parameters of the comprehensive patient-specific model are changed or perturbed to simulate various conditions or treatment options, and then the patient specific model is recalculated to predict the effect of the conditions or treatment options. | 01-26-2012 |
20120072190 | Method and System for Non-Invasive Assessment of Coronary Artery Disease - A method and system for non-invasive patient-specific assessment of coronary artery disease is disclosed. An anatomical model of a coronary artery is generated from medical image data. A velocity of blood in the coronary artery is estimated based on a spatio-temporal representation of contrast agent propagation in the medical image data. Blood flow is simulated in the anatomical model of the coronary artery using a computational fluid dynamics (CFD) simulation using the estimated velocity of the blood in the coronary artery as a boundary condition. | 03-22-2012 |
20120203530 | Method and System for Patient-Specific Computational Modeling and Simulation for Coupled Hemodynamic Analysis of Cerebral Vessels - A method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels is disclosed. An anatomical model of a cerebral vessel is extracted from 3D medical image data. The anatomical model of the cerebral vessel includes an inner wall and an outer wall of the cerebral vessel. Blood flow in the cerebral vessel and deformation of the cerebral vessel wall are simulated using coupled computational fluid dynamics (CFD) and computational solid mechanics (CSM) simulations based on the anatomical model of the cerebral vessel. | 08-09-2012 |
20130132054 | Method and System for Multi-Scale Anatomical and Functional Modeling of Coronary Circulation - A method and system for multi-scale anatomical and functional modeling of coronary circulation is disclosed. A patient-specific anatomical model of coronary arteries and the heart is generated from medical image data of a patient. A multi-scale functional model of coronary circulation is generated based on the patient-specific anatomical model. Blood flow is simulated in at least one stenosis region of at least one coronary artery using the multi-scale function model of coronary circulation. Hemodynamic quantities, such as fractional flow reserve (FFR), are computed to determine a functional assessment of the stenosis, and virtual intervention simulations are performed using the multi-scale function model of coronary circulation for decision support and intervention planning. | 05-23-2013 |
20130144573 | Method and System for Patient-Specific Hemodynamic Assessment of Virtual Stent Implantation - A method and system for assessment of virtual stent implantation in an aortic aneurysm is disclosed. A patient-specific 4D anatomical model of the aorta is generated from the 4D medical imaging data. A model representing mechanical properties of the aorta wall is adjusted to reflect changes due to aneurysm growth at a plurality of time stages. A stable deformation configuration of the aorta is generated for each time stages by performing fluid structure interaction (FSI) simulations using the patient-specific 4D anatomical model at each time stage based on the adjusted model representing the mechanical properties of the aorta wall at each time stage. Virtual stent implantation is performed for each stable deformation configuration of the aorta and FSI simulations are performed for each virtual stent implantation. | 06-06-2013 |
20130191100 | BLOOD FLOW COMPUTATION IN VESSELS WITH IMPLANTED DEVICES - A method for modeling blood flow through a flow diverter includes receiving a medical image containing blood vessels. Vessel geometry is extracted from the received medical image. Inlets and outlets are tagged within the extracted vessel geometry. A desired flow diverter is selected. A model of the selected flow diverter is generated within the imaged blood vessel, the model representing the flow diverter as a tube having a porous surface characterized by a viscous resistance and an inertial resistance. A course of blood flow though the flow diverter is predicted based on the generated model, the extracted vessel geometry, and the tagged inlets and outlets. | 07-25-2013 |
20130197884 | Method and System for Advanced Measurements Computation and Therapy Planning from Medical Data and Images Using a Multi-Physics Fluid-Solid Heart Model - Method and system for computation of advanced heart measurements from medical images and data; and therapy planning using a patient-specific multi-physics fluid-solid heart model is disclosed. A patient-specific anatomical model of the left and right ventricles is generated from medical image patient data. A patient-specific computational heart model is generated based on the patient-specific anatomical model of the left and right ventricles and patient-specific clinical data. The computational model includes biomechanics, electrophysiology and hemodynamics. To generate the patient-specific computational heart model, initial patient-specific parameters of an electrophysiology model, initial patient-specific parameters of a biomechanics model, and initial patient-specific computational fluid dynamics (CFD) boundary conditions are marginally estimated. A coupled fluid-structure interaction (FSI) simulation is performed using the initial patient-specific parameters, and the initial patient-specific parameters are refined based on the coupled FSI simulation. The estimated model parameters then constitute new advanced measurements that can be used for decision making. | 08-01-2013 |
Patent application number | Description | Published |
20100274943 | LINE-CARD DISABLING FOR POWER MANAGEMENT - A power management apparatus is configured to manage a switch having line-cards with ports. The management apparatus includes a tracking module configured to track activity for each port in a line-card in the switch, and a control module configured to determine whether the line-card is to be disabled. The management apparatus also includes output module configured to initiate a deactivation process for the line-card if all the ports are inactive. | 10-28-2010 |
20100278069 | Flow Path Discovery In Network To Guarantee Multiple Metric QoS Constraints - Route discovery for an end-to-end path in a network is performed for a flow. A path is attempted to be discovered that satisfies QoS constraints for multiple metrics for the flow. The route discovery includes determining whether a path request for a path satisfying the QoS constraints is feasible, infeasible or undecideable based on information in a local QoS table. If the path request is determined to be undecideable, route discovery is performed with neighbors. | 11-04-2010 |
20100278117 | WIRELESS CHANNEL SWITCHING USING CO-LOCATED RADIOS - A channel management system in a wireless network includes a master radio and a surrogate radio. The master radio performs data communication with one or more clients on a first channel in the wireless network, and the surrogate radio simultaneously scans other channels in the wireless network. A channel manager determines if a channel switch is needed, and the data communication is switched to a second channel based on the scanning of the other channels. | 11-04-2010 |
20110055611 | SYSTEM FOR CONTROLLING POWER CONSUMPTION OF A NETWORK - A system for controlling power consumption of a network includes at least one terminal to receive a plurality of requests to route data from a plurality of data sources to a plurality of data sinks, where the data sources and the data sinks are connected to each other through a plurality of network nodes forming the network, and a network configuration unit. The network configuration unit includes a selection module configured to select a configuration of the network nodes that allows the network to have a lowest overall power consumption of the network among a plurality of configurations of the network, and an output module configured to output a plurality of instruction signals to the network nodes to perform the network configuration. A network path for transmitting a network flow is selected that does not allow the network flow to be split and flow through another network path. | 03-03-2011 |
Patent application number | Description | Published |
20100050139 | DATA PROCESSING DEVICE DESIGN TOOL AND METHODS - A method of designing a data processing device design includes determining thermal profile information to indicate a predicted operating temperature for a device instance in the design. The device instance is associated with a first library cell having a relatively high threshold voltage characteristic. A cost function value is determined for the device instance based on the thermal profile information and based on timing information for data paths associated with the device instance. Based on the cost function value, the library cell associated with the device instance can be changed to a cell having a higher threshold voltage characteristic. | 02-25-2010 |
20100235159 | POWER ESTIMATION METHOD AND DEVICE THEREFOR - A set of instructions executable at an integrated circuit is partitioned into multiple instruction blocks. A first and second instruction block are executed multiple times, including a first execution and a second execution. The first execution of the first instruction block is associated with a first set of executions, and the first execution of the second instruction block is associated with a second set of executions. A first amount of energy consumption representative of a member of the first set of executions is determined, and a second amount of energy consumption representative of a member of the second set of executions is determined. The first amount of energy is assigned to each member of the first set, and the second amount of energy is assigned to each member of the second set, and used to determine a total amount of energy consumption associated with execution of the set of instructions. | 09-16-2010 |
20110258588 | INTEGRATED CIRCUIT DEVICE WITH REDUCED LEAKAGE AND METHOD THEREFOR - A method implemented at a computer aided design tool includes preferentially placing fill regions adjacent to transistors of a first conductivity type for a plurality of standard cell instances of a device design to reduce leakage of the plurality of standard cell instances. Preferentially placing the fill regions includes preferentially placing the fill regions adjacent to transistors of a first conductivity type as compared to placing the fill regions adjacent to transistors of a second conductivity type that is opposite the first conductivity type. | 10-20-2011 |
20120217646 | VIAS BETWEEN CONDUCTIVE LAYERS TO IMPROVE RELIABILITY - Another semiconductor device includes a first layer including a plurality of electrically conductive wires, a second layer, a plurality of non-functional via pads are included in the second layer or between the first layer and the second layer. A dangling via is included within a specified area of the first layer. The dangling vias connect one or more of the wires in the first layer to a respective one of the via pads. | 08-30-2012 |
20130074026 | LAYOUT TECHNIQUE FOR STRESS MANAGEMENT CELLS - An integrated circuit device layout is created based on charge carrier mobility characteristics of the device's non-functional cells. The charge carrier mobility of the non-functional cells can alter behavioral characteristics such as the hold time, setup time, or leakage current of nearby functional logic cells. Accordingly, a layout tool creates the layout for the integrated circuit device by selecting and placing non-functional cells having different mobility so as to selectively alter the characteristics of nearby logic cells. | 03-21-2013 |
20140132293 | INTEGRATED CIRCUIT WITH DEGRADATION MONITORING - An integrated circuit including a degradation monitoring circuit. The degradation monitoring circuit includes a comparison circuit having a programmable delay element including an input coupled to a data node of a timing path and having an output to provide a delayed signal of a data signal of the data node that is delayed by a programmable amount. The comparison circuit includes a logic comparator that provides a logic comparison between a data signal of the data node and the output of the delay element. The monitoring circuit includes a sampling circuit that provides a sampled signal of the output of the logic comparator that is a sampled with respect to a clock signal of the clock signal line. The monitoring circuit includes a hold circuit that provides a signal indicative of a data signal of the data node transitioning within a predetermined time of an edge transition of a clock signal of the clock signal line. | 05-15-2014 |
Patent application number | Description | Published |
20100092891 | PITCH REDUCED PATTERNS RELATIVE TO PHOTOLITHOGRAPHY FEATURES - Differently-sized features of an integrated circuit are formed by etching a substrate using a mask which is formed by combining two separately formed patterns. Pitch multiplication is used to form the relatively small features of the first pattern and conventional photolithography used to form the relatively large features of the second pattern. Pitch multiplication is accomplished by patterning a photoresist and then etching that pattern into an amorphous carbon layer. Sidewall spacers are then formed on the sidewalls of the amorphous carbon. The amorphous carbon is removed, leaving behind the sidewall spacers, which define the first mask pattern. A bottom anti-reflective coating (BARC) is then deposited around the spacers to form a planar surface and a photoresist layer is formed over the BARC. The photoresist is next patterned by conventional photolithography to form the second pattern, which is then is transferred to the BARC. The combined pattern made out by the first pattern and the second pattern is transferred to an underlying amorphous silicon layer and the pattern is subjected to a carbon strip to remove BARC and photoresist material. The combined pattern is then transferred to the silicon oxide layer and then to an amorphous carbon mask layer. The combined mask pattern, having features of difference sizes, is then etched into the underlying substrate through the amorphous carbon hard mask layer. | 04-15-2010 |
20110140204 | TRANSISTORS WITH AN EXTENSION REGION HAVING STRIPS OF DIFFERING CONDUCTIVITY TYPE AND METHODS OF FORMING THE SAME - Methods of forming transistors and transistors are disclosed, such as a transistor having a gate dielectric over a semiconductor having a first conductivity type, a control gate over the gate dielectric, source and drain regions having a second conductivity type in the semiconductor having the first conductivity type, and strips having the second conductivity type within the semiconductor having the first conductivity type and interposed between the control gate and at least one of the source and drain regions. | 06-16-2011 |
20120313691 | ELECTROMAGNETIC SHIELD AND ASSOCIATED METHODS - Semiconductor devices are described, along with methods and systems that include them. One such device includes a diffusion region in a semiconductor material, a terminal coupled to the diffusion region, and a field plate coupled to the terminal and extending from the terminal over the diffusion region to shield the diffusion region. Additional embodiments are also described. | 12-13-2012 |
20140339648 | TRANSISTORS WITH AN EXTENSION REGION HAVING STRIPS OF DIFFERING CONDUCTIVITY TYPE - A transistor includes a gate dielectric over a semiconductor having a first conductivity type, a control gate over the gate dielectric, source and drain regions having a second conductivity type in the semiconductor having the first conductivity type, and strips having the second conductivity type within the semiconductor having the first conductivity type and interposed between the control gate and at least one of the source and drain regions. | 11-20-2014 |
20150021707 | ELECTROMAGNETIC SHIELD AND ASSOCIATED METHODS - Semiconductor devices are described, along with methods and systems that include them. One such device includes a diffusion region in a semiconductor material, a terminal coupled to the diffusion region, and a field plate coupled to the terminal and extending from the terminal over the diffusion region to shield the diffusion region. Additional embodiments are also described. | 01-22-2015 |
Patent application number | Description | Published |
20110128920 | Channel Assignment For A Wireless Network - Channel assignment for access points (APs) in a wireless network includes determining a bottleneck client in an interference relationship, and determining a channel assignment for the APs that maximizes a normalized throughput of the bottleneck client. The normalized throughput is assigned to the bottleneck client, and the bottleneck client is assigned to a fixed set. | 06-02-2011 |
20110196964 | MANAGING EVENT TRAFFIC IN A NETWORK SYSTEM - A network system and associated operating methods manage event storms. The network system comprises an event analysis and control engine that detects and manages events occurring on a network. The event analysis and control engine receives events from a plurality of agents, and analyzes the events according to policies specified in a policies templates database. The event analysis and control engine processes raw network packets directly with less than full packet parsing to generate a filtered stream of events based on the analysis. The event analysis and control engine propagates the filtered stream of events to a monitoring system. | 08-11-2011 |
20110261688 | Priority Queue Level Optimization for a Network Flow - Optimizing priority queue levels for a flow in a network includes determining a path for the flow, determining an optimized priority queue level of the flow at each of a plurality of switches based on a Quality of Service (QoS) requirement of the flow and priority queue levels of one or more existing flows in the network. Information of the optimized priority queue level of the flow is sent to at each of the switches. | 10-27-2011 |
20110261831 | Dynamic Priority Queue Level Assignment for a Network Flow - Forwarding a flow in a network includes receiving the flow at a switch, determining an optimized priority queue level of the flow at the switch, and forwarding the flow via the switch using an optimized priority queue level of the flow at the switch. The flow passes through a plurality of switches, including the switch, in the network, and the optimized priority queue level of the flow at the switch is different from a priority queue level of the flow at a second switch of the plurality of switches. The second switch routes the flow at the second switch using the different priority queue level for the flow. | 10-27-2011 |
20110273988 | Distributing decision making in a centralized flow routing system - Local rules for managing flows devolved from a central controller are received at a switch. The central controller determines a global set of rules for managing flows. The switch receives a packet from a flow from a network and determines whether a metric for the flow satisfies a dynamic condition to trigger a metric report to the central controller. In response to a determination that the metric for the flow at the switch satisfies the dynamic condition to trigger a metric report to the central controller, the switch sends a metric report to the central controller, and the switch then receives an instruction to manage the flow from the central controller. In response to a determination that the metric for the flow at the switch does not satisfy the dynamic condition to trigger the metric report to the central controller, the switch manages the flow using the local rules for managing flows. | 11-10-2011 |
20110292886 | CHANNEL ASSIGNMENT FOR A WIRELESS NETWORK - Channel assignment for access points (APs) in a wireless network includes determining at least one of a MaxSum and a MaxMin, and determining a channel assignment for the APs based on at least one of the MaxSum and the MaxMin. The MaxSum is a maximization of a system throughput and the system throughput is a sum of throughput of nodes in the network. The MaxMin is a maximization of a minimum throughput of a set of AP-client links in the network. The AP-client link is a link between an AP and a client associated with the AP. | 12-01-2011 |
20120026899 | PATH SWITCHING USING CO-LOCATED RADIOS IN A MULTI-HOP WIRELESS NETWORK - A node in a multi-hop wireless network includes a master radio and a surrogate radio. The master radio performs data communication on a main multi-hop path in the multi-hop wireless network, and the surrogate radio simultaneously scans one or more channels in the multi-hop wireless network. A channel manager determines if a link between two different nodes on the main multi-hop path is disconnected, and, in response to determining a disconnection of the link between two different nodes on the main multi-hop path, the data communication is switched to an alternative multi-hop path in the multi-hop wireless network based on information obtained from the scanning of the one or more channels. | 02-02-2012 |
20120120958 | DEEP SLEEP MODE MANAGEMENT FOR A NETWORK SWITCH | 05-17-2012 |
20120155264 | Dynamic Balancing Priority Queue Assignments for Quality-of-Service Network Flows - A priority queue assignment technique for quality-of-service (“QoS”) network flows in a network is provided. A network path is determined for an incoming flow including a plurality of network switches associated, with a plurality of priority queue levels. A priority queue level is determined for the incoming flow for at least one of the plurality of network switches in the network path based on priority queue levels of existing flows. The priority queue level of the incoming flow is adjusted, to dynamically balance flows over the plurality of priority queue levels for at least one of the plurality of network switches in the network path based on quality-of-service (“QoS”) requirements associated with the incoming flow. | 06-21-2012 |
20130262661 | SOLVING UNDER-DETERMINED PROBLEMS FOR NETWORKS - There is provided a computer-implemented method of solving an under-determined problem. The method includes partitioning the under-determined problem into a plurality of sub-problems of reduced order. The method also includes receiving a plurality of local solutions to the plurality of sub-problems. Additionally, the method includes fusing the local solutions to generate a global solution to the under-determined problem. | 10-03-2013 |
20130287032 | UPDATING VIRTUAL NETWORK MAPS - A switch determines a path, not included in a first set of virtual networks associated with the switch. It is determined if the path can be added to an existing virtual network in the first set of virtual networks. If the path cannot be added, a new virtual network is created to include the path. | 10-31-2013 |
20130287033 | ROUTING DATA PACKETS ON A NETWORK - A plurality of data flows can be routed from a first node of the network to one or more other nodes of the network. A destination of a data packet for each data flow is determined. When the destination node of the data packet of that data flow is not adjacent to the first node, a probabilistic determination is made for a next hop of data packets of that data flow. When the destination node of the data packet of that data flow is adjacent to the first node, a priority designation is made for the next hop of data packets of that data flow as being the destination node. The next hop for data packets of the data flow is determined based on either the probabilistic determination or the priority designation. | 10-31-2013 |
20130287034 | USING PROBABILISTIC VALUES FOR ROUTING DATA PACKETS ON A DATA CENTER NETWORK - A set of virtual local area networks (VLANs) are defined from a set of nodes that comprise a data center network. A set of possible paths are determined for routing data packets from a root node to one or more other nodes of the set of nodes. A set of probabilistic values are identified for determining a path in the set of possible paths that individual data packets are to take as between the root node and a destination node specified by the individual data packet. The data packets are routed to the destination node specified by that data packet, along a path that is determined by use of the set of probabilistic values. The path may be provided by one or more VLANs. | 10-31-2013 |
20140020100 | DETECTING NETWORK ANOMALY - A method for detecting an anomaly in a network can include combining a number of data-created sketch-sets and requesting a finer sketch-set for an identified sketch-set among the combined number of sketch-sets using an aggregator, and creating the finer sketch-set for the identified sketch-set to detect the anomaly in the network using a monitor. | 01-16-2014 |
20140153388 | RATE LIMIT MANAGERS TO ASSIGN NETWORK TRAFFIC FLOWS - A rate limit manager is to assign network traffic flows to hardware rate limiters. The network traffic flows are associated with rate limit values. The rate limit manager determines threshold values to assign flow(s) to hardware rate limiters, and the rate limit manager is to assign flow(s) to a last remaining unassigned hardware rate limiter independent of the threshold value. | 06-05-2014 |
20140258498 | Implementing an Energy Proportional Network Architecture from Desired Network Criteria - Systems, methods, and computer-readable executable instructions are provided for implementing an energy proportional network architecture. Implementing an energy proportional network architecture can include determining a number of desired network criteria and a desired number of access ports. A number of switches for the energy proportional network architecture can be calculated from the desired number of access ports and the number of desired network criteria. Implementing an energy proportional network architecture can also include using the number of calculated switches to form the energy proportional network. | 09-11-2014 |
20150095498 | Allocating Bandwidth in a Network - Allocating bandwidth in a network ( | 04-02-2015 |
Patent application number | Description | Published |
20130243294 | Method and System for Hemodynamic Assessment of Aortic Coarctation from Medical Image Data - A method and system for non-invasive hemodynamic assessment of aortic coarctation from medical image data, such as magnetic resonance imaging (MRI) data is disclosed. Patient-specific lumen anatomy of the aorta and supra-aortic arteries is estimated from medical image data of a patient, such as contrast enhanced MRI. Patient-specific aortic blood flow rates are estimated from the medical image data of the patient, such as velocity encoded phase-contrasted MRI cine images. Patient-specific inlet and outlet boundary conditions for a computational model of aortic blood flow are calculated based on the patient-specific lumen anatomy, the patient-specific aortic blood flow rates, and non-invasive clinical measurements of the patient. Aortic blood flow and pressure are computed over the patient-specific lumen anatomy using the computational model of aortic blood flow and the patient-specific inlet and outlet boundary conditions. | 09-19-2013 |
20130246034 | Method and System for Non-Invasive Functional Assessment of Coronary Artery Stenosis - A method and system for non-invasive assessment of coronary artery stenosis is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient acquired during rest state. Patient-specific rest state boundary conditions of a model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Patient-specific rest state boundary conditions of the model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Hyperemic blood flow and pressure across at least one stenosis region of the coronary arteries are simulated using the model of coronary circulation and the patient-specific hyperemic boundary conditions. Fractional flow reserve (FFR) is calculated for the at least one stenosis region based on the simulated hyperemic blood flow and pressure. | 09-19-2013 |
20140024932 | Computation of Hemodynamic Quantities From Angiographic Data - Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described. | 01-23-2014 |
20140058715 | Method and System for Non-Invasive Functional Assessment of Coronary Artery Stenosis - A method and system for non-invasive assessment of coronary artery stenosis is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient acquired during rest state. Patient-specific rest state boundary conditions of a model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Patient-specific rest state boundary conditions of the model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Hyperemic blood flow and pressure across at least one stenosis region of the coronary arteries are simulated using the model of coronary circulation and the patient-specific hyperemic boundary conditions. Fractional flow reserve (FFR) is calculated for the at least one stenosis region based on the simulated hyperemic blood flow and pressure. | 02-27-2014 |
20140088935 | VISCOELASTIC MODELING OF BLOOD VESSELS - A method for modeling a blood vessel includes: (a) modeling a first segment of the blood vessel based on medical imaging data acquired from a subject; (b) computing a first modeling parameter at an interior point of the first segment; and (c) computing a second modeling parameter at a boundary point of the first segment using a viscoelastic wall model. Systems for modeling a blood vessel are described | 03-27-2014 |
20140136174 | System and Method for Patient Specific Modeling of Liver Tumor Ablation - A method and system for tumor ablation planning and guidance based on a patient-specific model of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the venous system of the liver. Cellular necrosis in the liver is simulated based on the simulated heat diffusion. A visualization of a simulated necrosis region is generated and displayed to the user for decision making and optimal therapy planning and guidance. | 05-15-2014 |
20140236547 | PATIENT-SPECIFIC AUTOMATED TUNING OF BOUNDARY CONDITIONS FOR DISTAL VESSEL TREE - Boundary conditions for a distal vessel tree are modeled and tuned to a specific patient. Measurements from the patient are used to find reference compliance and resistance for the root of the distal vessel tree model. The reference compliance and resistance are used to tune properties of a structured tree model, such as by iteratively solving for the properties while matching the compliance and resistance of the structured tree model to the patient-specific reference compliance and reference resistance. The tuned structured tree is then used to calculate boundary conditions for computing flow of a scanned vessel of the patient. | 08-21-2014 |
20140249399 | Determining Functional Severity of Stenosis - A method for determining functional severity of a stenosis includes: (a) generating a simulated perfusion map from a calculated blood flow; (b) comparing the simulated perfusion map to a measured perfusion map to identify a degree of mismatch therebetween, the measured perfusion map representing perfusion in a patient; (c) modifying a parameter in a model used in calculating the blood flow when the degree of mismatch meets or exceeds a predefined threshold; (d) computing a hemodynamic quantity from the simulated perfusion map when the degree of mismatch is less than the predefined threshold, the hemodynamic quantity being indicative of the functional severity of the stenosis; and (e) displaying the hemodynamic quantity. Systems for determining functional severity of a stenosis are described. | 09-04-2014 |
20140296842 | Patient Specific Planning and Simulation of Ablative Procedures - Patient specific temperature distribution in organs, due to an ablative device, is simulated. The effects of ablation are modeled. The modeling is patient specific. The vessel structure for a given patient, segmented from medical images, is accounted for as a heat sink in the model of biological heat transfer. A temperature map is generated to show the effects of ablation in a pre-operative analysis. Temperature maps resulting from different ablation currents and ablation device positions may be used to determine a more optimal location of the ablative device for a given patient. Other models may be included, such as accounting for the tissue damage during the ablation. | 10-02-2014 |
20150051888 | FRAMEWORK FOR PERSONALIZATION OF CORONARY FLOW COMPUTATIONS DURING REST AND HYPEREMIA - Embodiments relate to non-invasively determining coronary circulation parameters during a rest state and a hyperemic state for a patient. The blood flow in the coronary arteries during a hyperemic state provides a functional assessment of the patient's coronary vessel tree. Imaging techniques are used to obtain an anatomical model of the patient's coronary tree. Rest boundary conditions are computed based on non-invasive measurements taken at a rest state, and estimated hyperemic boundary conditions are computed. A feedback control system performs a simulation matching the rest state utilizing a model based on the anatomical model and a plurality of controllers, each controller relating to respective output variables of the coronary tree. The model parameters are adjusted for the output variables to be in agreement with the rest state measurements, and the hyperemic boundary conditions are accordingly adjusted. The hyperemic boundary conditions are used to compute coronary flow and coronary pressure variables. | 02-19-2015 |
20150063649 | Method and System for Blood Flow Velocity Reconstruction From Medical Images - A method and system for blood flow velocity reconstruction from medical image data is disclosed. Flow system geometry of a flow conduit is generated from medical image data. The flow system velocity includes an inlet, walls, and one or more outlets of the flow conduit. A measured velocity field is extracted from the medical image data. Inlet and wall fluxes are estimated based on the measured velocity field or other external measurements. Outlet fluxes are estimated such that mass conservation is constrained based on the inlet and wall fluxes. A reconstructed velocity field is calculated by solving flux-constrained Poisson (FCP) equations that are constrained by the estimated output fluxes | 03-05-2015 |
20150065864 | Method and System for Functional Assessment of Renal Artery Stenosis from Medical Images - A method and system for non-invasive assessment of renal artery stenosis is disclosed. A patient-specific anatomical model of at least a portion of the renal arteries and aorta is generated from medical image data of a patient. Patient-specific boundary conditions of a computational model of blood flow in the portion of the renal arteries and aorta are estimated based on the patient-specific anatomical model. Blood flow and pressure are simulated in the portion of the renal arteries and aorta using the computational model based on the patient-specific boundary conditions. At least one hemodynamic quantity characterizing functional severity of a renal stenosis region is calculated based on the simulated blood flow and pressure in the portion of the renal arteries and aorta. | 03-05-2015 |
20150112182 | Method and System for Machine Learning Based Assessment of Fractional Flow Reserve - A method and system for determining fractional flow reserve (FFR) for a coronary artery stenosis of a patient is disclosed. In one embodiment, medical image data of the patient including the stenosis is received, a set of features for the stenosis is extracted from the medical image data of the patient, and an FFR value for the stenosis is determined based on the extracted set of features using a trained machine-learning based mapping. In another embodiment, a medical image of the patient including the stenosis of interest is received, image patches corresponding to the stenosis of interest and a coronary tree of the patient are detected, an FFR value for the stenosis of interest is determined using a trained deep neural network regressor applied directly to the detected image patches. | 04-23-2015 |