Pierce, CA
Brendan Pierce, San Jose, CA US
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20130334787 | BICYCLE SEAT WITH ADJUSTABLE STIFFNESS - A bicycle seat including a mount adapted to be coupled to a bicycle frame, a shell supported by the mount, and a tensioned element extending from a first anchor point to a second anchor point. The shell includes a flexible portion for supporting a rider, and the tensioned element includes a support portion providing support to the flexible portion between the first and second anchor points. | 12-19-2013 |
Brendan Erik Pierce, San Jose, CA US
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20160000170 | HELMET WITH RETRACTABLE VISOR AND BRIDGE - A helmet comprises an outer shell, a visor movable between a retracted position and a deployed position and a movable bridge that is positionable against a user's face. The visor moves along an arc-shaped track and/or a pivot from a position stored within the helmet shell to a deployed position in front of the face and the bridge is moved against the user's face. The helmet and integrated bridge assembly provides a seal from the visor to the user's face, thus protecting the face against wind and other debris. | 01-07-2016 |
Brian Pierce, Moreno Valley, CA US
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20150130656 | Method and Apparatus for Enhanced Multi-Node Utilization of an Electromagnetic State Space - Methods and systems are provided for efficiently packing nodes within an electromagnetic state space. | 05-14-2015 |
Brian Pierce, Chico, CA US
Patent application number | Description | Published |
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20110040295 | Cancer treatment using selective photo-apoptosis - A system for cancer treatment comprises a processor and a memory. The processor is configured to receive a target type and a host type and determine one or more illumination source characteristics such that: an illumination of the target type employing the one or more illumination source characteristics induces apoptosis in the target type without initiating thermolysis or ablation of the target type; and an illumination of the host type employing the one or more illumination source characteristics does not substantially induce apoptosis, thermolysis, or ablation in the host type. The memory is coupled to the processor and configured to provide the processor with instructions. | 02-17-2011 |
20120000163 | REDUCTION OF PATHOGENS FOR FOOD IN PACKAGING - A system for reducing pathogens for food in packaging comprises a bagger and pathogen reducer. The bagger is for inserting a food item into a package. The pathogen reducer is for reducing pathogens by exposing the food item and the package with the food item inside using infrared energy. | 01-05-2012 |
Brian N. Pierce, Chico, CA US
Patent application number | Description | Published |
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20080208294 | DISINFECTION, DESTRUCTION OF NEOPLASTIC GROWTH, AND STERILIZATION BY DIFFERENTIAL ABSORPTION OF ELECTROMAGNETIC ENERGY - Neoplastic tissue, viral and bacterial infections, and other physiological disorders and conditions are treated by irradiation of the host with electromagnetic radiation at a wavelength that is differentially absorbed by the offending tissue or cells. Radiation with differential absorption is also used in the sterilization of articles and packing made from synthetic polymers and for the treatment of food stuffs. | 08-28-2008 |
20140222116 | DISINFECTION, DESTRUCTION OF NEOPLASTIC GROWTH, AND STERILIZATION BY DIFFERENTIAL ABSORPTION OF ELECTROMAGNETIC ENERGY - Neoplastic tissue, viral and bacterial infections, and other physiological disorders and conditions are treated by irradiation of the host with electromagnetic radiation at a wavelength that is differentially absorbed by the offending tissue or cells. Radiation with differential absorption is also used in the sterilization of articles and packing made from synthetic polymers and for the treatment of food stuffs. | 08-07-2014 |
Carrick Pierce, Alameda, CA US
Patent application number | Description | Published |
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20160138268 | STEEL BAR SEALING APPARATUS AND METHOD - A bar sealing apparatus includes a hollow, cylindrical intermediate end cap. The end cap has a fitting disposed within an opening. The sealing apparatus further has a hollow, cylindrical terminal end cap and a hollow, cylindrical sleeve that is configured to surround the bar. Internal threads or other fasteners of the fitting may be threaded onto the bar, and internal threads or other fasteners of the intermediate end cap and internal threads or other fasteners of the terminal end cap may be threaded onto external threads or other fasteners of the sleeve. The intermediate end cap, terminal end cap, and sleeve facilitate grout to fill a space between each of the intermediate end cap, terminal end cap, sleeve, and the bar. | 05-19-2016 |
Christian Pierce, Truckee, CA US
Patent application number | Description | Published |
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20140310071 | PHYSICALLY-BASED FINANCIAL ANALYSIS AND/OR FORECASTING METHODS, APPARATUS, AND SYSTEMS - Methods and apparatus for modeling well production. Such methods comprise modeling a production of a well (perhaps an open universe, generative model). Methods also comprise determining probability distributions for physical parameters associated with the well by training the model with historic well production data (perhaps using sparse sampling). Such methods also comprise determining a posterior distribution for the model by sampling probability distributions for the parameters. Some methods further comprise determining a posterior distribution for the well's production using the model's posterior distribution. Non-Gaussian (Laplacian) noise can be added to the model. Methods can comprise financially modeling the well. Some methods comprise using MCMC sampling to converge the parameter posterior distribution for the well's production. An EUR for the well can be determined along with an uncertainty associated with the posterior distribution for the production. If desired, some methods comprise modeling multi-phase flow in the well. | 10-16-2014 |
Christopher R. Pierce, Oakland, CA US
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20120082775 | Method and apparatus for oil-free production of food products in a rotary impingement oven - A rotary air impingement oven enables volume production of oil-free food products including those from root crops such as potato chips. The oven contains a cage-like drum with perforate or foraminous sidewalls rotatably disposed within the oven such that the sidewalls, containing product therein, are exposed to temperature and velocity controlled impinging process vapor which is withdrawn continuously during drum rotation. The food products within the drum are urged by an internal baffle towards the drum discharge during rotation. | 04-05-2012 |
Clark Pierce, Los Angeles, CA US
Patent application number | Description | Published |
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20090187514 | INTERACTIVE WEB BASED EXPERIENCE VIA EXPERT RESOURCE - A system providing an interactive web based experience via an expert resource is provided. In this system, virtual experts field questions from end users, letting the users have control over an information-on-demand experience. | 07-23-2009 |
20090187850 | SYSTEM AND METHOD FOR MULTI-SCREEN EXPERIENCE - A system and method for multi-screen experience, which comprises provision of multiple screens of information to a viewer at the same time. In an exemplary embodiment, a plurality of screens, each showing different angles of an event, are simultaneously provided to the user. In another exemplary embodiment, a given screen may be selected for full screen viewing or deselected for multi-screen viewing. In another exemplary embodiment, an identifier indicates, charts or illustrates how a given screen relates to an event. | 07-23-2009 |
20140337763 | SYSTEM, METHOD AND INTERFACE FOR PRESENTING EVENT COVERAGE USING PLURAL CONCURRENT INTERFACE PORTIONS - A system, method and interface for presenting event coverage using plural concurrent interface portions is provided including concurrent interface portions, each interface portion including different classes of event information. | 11-13-2014 |
20150358680 | SYSTEM, METHOD AND INTERFACE FOR PRESENTING EVENT COVERAGE USING PLURAL CONCURRENT INTERFACE PORTIONS - A system, method and interface for presenting event coverage using plural concurrent interface portions is provided including concurrent interface portions, each interface portion including different classes of event information. | 12-10-2015 |
Cory Pierce, Durham, CA US
Patent application number | Description | Published |
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20090293741 | SYSTEM, DEVICE AND METHOD FOR PROCESSING HARVESTED WALNUTS - A system and method for processing harvested walnuts that includes a walnut separator for separating walnuts without hulls from walnuts with hulls prior to a hulling process in order to increase productivity of the huller. A huller by-pass system conveys walnuts without hulls to a post-hulling processing. A walnut separator may include a screen having a selected screen size that permit walnuts without hulls to pass through the screen and prohibit walnuts with hulls and therefore a larger diameter, to pass through the screen. Alternately the walnut separator may include an optical sensor positioned to scan harvested walnuts. A controller connected to the optical sensor processes input from the optical sensor and selectively actuates a walnut selection or ejection device causing a walnut to by-pass a process. | 12-03-2009 |
Daniel W. Pierce, Hayward, CA US
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20090068693 | HIGH SENSITIVITY ASSAY FOR DETECTION OF NUCLEOSIDE DIPHOSPHATE PRODUCTION - The present invention provides assays for detecting ADP, GDP and inorganic phosphate. These assays can be used directly to detect the presence of ADP, GDP and inorganic phosphate or can be used as part of a number of methods for identifying candidate agents that bind to a target protein or serve as modulators of the biological activity of a target protein. | 03-12-2009 |
Dennis C. Pierce, Pleasanton, CA US
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20090221217 | SOLAR PANEL EDGE DELETION MODULE - The present invention generally relates to an edge deletion module positioned within an automated solar cell fabrication line. The edge deletion module may include a grinding wheel device for removing material from edge regions of a solar cell device and cleaning the edge regions of the solar cell device after removing the material. The edge deletion module may also include an abrasive element, a portion of which is ground as it is periodically, laterally advanced toward the grinding wheel device. A controller is provided for controlling the operation and function of various facets of the module. | 09-03-2009 |
Elisha George Pierce, Palo Alto, CA US
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20130298426 | Tongueless Footwear With A Canopy - A tongueless footwear includes a sole, a first side, an opposing second side, a canopy and a fastening system. The canopy is coupled to the first side and configured to extend over the second side thereby providing substantially direct support for the ankle and instep of a user. The fastening system is configured to securely fasten the canopy to the second side, and can include a toggle system with a cord, anchors and a cord tensioner | 11-14-2013 |
Glenn Pierce, Rancho Santa Fe, CA US
Patent application number | Description | Published |
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20100086598 | TRAVERSAL OF NUCLEIC ACID MOLECULES THROUGH A FLUID SPACE AND EXPRESSION IN REPAIR CELLS - Disclosed are methods for use in transferring nucleic acids into cells at a wound site associated with a fluid space. These gene transfer protocols are suitable for use in transferring various nucleic acids into cartilage, cardiac muscle, and other tissues, and have many uses including treating diseases such as arthritis and ischemic heart disease, and promoting wound healing. The invention further disclosed pharmaceutical compositions that may be used in the practice of the invention to transfer the nucleic acid of interest. Such compositions include any multi-partitioned biocompatible matrix in combination with multiple nucleic acids of interest. | 04-08-2010 |
20110077202 | Targeted Coagulation Factors and Method of Using the Same - Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A. | 03-31-2011 |
20110286988 | FVIII Muteins for Treatment of Von Willebrand Disease - This invention relates to treatment of von Willebrand Disease by administration of Factor VIII muteins that are covalently bound, at a predefined site that is not an N-terminal amine, to one or more biocompatible polymers such as polyethylene glycol. The mutein conjugates retain FVIII procoagulant activity and have improved pharmacokinetic properties in subjects lacking von Willebrand Factor. | 11-24-2011 |
20130108629 | Factor VIII-Fc Chimeric and Hybrid Polypeptides, and Methods of Use Thereof | 05-02-2013 |
20130190391 | TRAVERSAL OF NUCLEIC ACID MOLECULES THROUGH A FLUID SPACE AND EXPRESSION IN REPAIR CELLS - Disclosed are methods for use in transferring nucleic acids into cells at a wound site associated with a fluid space. These gene transfer protocols are suitable for use in transferring various nucleic acids into cartilage, cardiac muscle, and other tissues, and have many uses including treating diseases such as arthritis and ischemic heart disease, and promoting wound healing. The invention further disclosed pharmaceutical compositions that may be used in the practice of the invention to transfer the nucleic acid of interest. Such compositions include any multi-partitioned biocompatible matrix in combination with multiple nucleic acids of interest. | 07-25-2013 |
20130274194 | Factor VIII-Fc Chimeric and Hybrid Polypeptides, and Methods of Use Thereof - The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells. | 10-17-2013 |
20140221618 | TARGETED COAGULATION FACTORS AND METHOD OF USING THE SAME - Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A. | 08-07-2014 |
20140294821 | FACTOR VIII CHIMERIC AND HYBRID POLYPEPTIDES, AND METHODS OF USE THEREOF - The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells | 10-02-2014 |
20150079072 | Assays to Monitor Bleeding Disorders - The present invention provides methods of dosing Factor VIII or Factor IX chimeric and hybrid polypeptides. The present invention further provides high-sensitivity methods of quantifying an amount of activated FIX protein in a test sample | 03-19-2015 |
Griffin Pierce, Chula Vista, CA US
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20150018074 | Mobile gaming application - The mobile gaming application is a specific process by which a person may download a free or paid version of the application from the internet and is able to search for live play at physical casinos or search for online casinos and various card games being played at that time and in the near future. By searching by state, county, and city and even zip code the person searching will find casino card games of their choice by using their cell phone, lap top, or computer and being able to reserve a seat at that table for live or online games and be able buy in to those games mobile using GPS and through existing casino software or by using specific software offered the mobile application itself. The application maintains a permanent record of wins and losses over short or long periods of time and allows sharing on social media for friends and fellow players to be a competition for a more effective function of the application. The application may link to existing casino software or is used for free search without the linking process. | 01-15-2015 |
Harold D. Pierce, Westlake Village, CA US
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20120294473 | Low cost programmable sound recording and playback device and method for communicating with, and recharging of, the device - A low cost sound recording and playback device and a low cost method for wirelessly communicating with, and recharging of, the device. The device utilizes commonly available electronic components generally included in electronic sound producing devices thereby allowing for lowest cost of manufacture. The device includes a low cost low-power processor, general purpose low-cost loudspeaker, and a power source. The method incorporates inductive coupling between an external communication and recharging device, and the internal loudspeakers voice coil of the device. Substantial reductions in cost and space savings are realized by utilizing the internal loudspeaker's voice coil for multiple purposes. | 11-22-2012 |
James Pierce, Torrance, CA US
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20090157775 | ARCHIVING METHOD AND SYSTEM - A method of archiving a set of source tables in a database system. Each source table has a plurality of rows. Initially, a consistency point for the set of source tables is established. The database system creates a log record for each change (insert, modify, or delete) effected to a row of the source tables subsequent to the consistency point. Substantially all source table rows are copied to an archive (a data storage object that is external to the database system). Then the accumulated log records for the affected source tables are distilled and appended to the archive. | 06-18-2009 |
Jeffrey Pierce, Sunnyvale, CA US
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20140280582 | RELATIONSHIP TRACKING AND MAINTENANCE - Disclosed are for aggregating communication data. Data pertaining to a plurality of users is received. A probability that a particular user of the plurality of users will likely have a future encounter with a first other user of the plurality of users based on the received data is determined. An identity of the first other user is provided. Communication content exchanged between the first other user and the particular user is also provided. | 09-18-2014 |
Jeffrey A. Pierce, Redwood City, CA US
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20100041164 | Mechanical device for mixing a fluid sample with a treatment solution - A method of preparing a fluid sample for use in a fluid analyte monitor, the method including drawing a fluid sample into a capillary channel in a body having a septum piercing projection; piercing a first septum covering a treatment solution chamber with the septum piercing projection, thereby exposing the fluid sample in the capillary channel to the contents of the treatment solution chamber; mixing the fluid sample with the contents of the treatment solution chamber; and piercing a second septum covering the treatment solution channel such that the mixed fluid and treatment solution chamber contents are received into a fluid analyte meter. The method may also include shaking the treatment solution chamber with the capillary channel therein, thereby mixing the fluid sample with the contents of the treatment solution chamber. | 02-18-2010 |
Jeffrey Charles Pierce, Santa Clara, CA US
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20110011743 | LOW POWER RF TUNING USING OPTICAL AND NON-REFLECTED POWER METHODS - Aspects of the present invention include methods and apparatuses that may be used for monitoring and adjusting plasma in a substrate processing system by using a plasma data monitoring assembly. In one embodiment, an apparatus for monitoring a plasma in a substrate processing system is provided. The apparatus includes a plasma chamber having a plurality of walls, at least one of the plurality of walls having a dielectric ceiling, at least one inner coil element and at least one outer coil element disposed outside the chamber, a current sensor coupled to one of the inner coil element or the outer coil element, the current sensor adapted to detect current from an inductively coupled plasma generated in the plasma chamber, an RF power source, and one or more adjustable capacitors coupled to each of the one or more coil elements. | 01-20-2011 |
20110263050 | LOW POWER RF TUNING USING OPTICAL AND NON-REFLECTED POWER METHODS - Aspects of the present invention include methods for controlling a plasma in a substrate processing system. One embodiment provides controlling a first set of wavelength intensities of reflected electromagnetic radiation reflected from the plasma within a chamber before processing a first set of one or more substrates, associating the first set of wavelength intensities of reflected electromagnetic radiation to an RF power within the processing system, adjusting a matching circuit based on the first set of wavelength intensities of reflected electromagnetic radiation, processing the first set of one or more substrates in the substrate processing system, controlling a second set of wavelength intensities of reflected electromagnetic radiation reflected from the plasma within the chamber, and associating the second set of wavelength intensities of reflected electromagnetic radiation to the RF power within the processing system. | 10-27-2011 |
Jeffrey L. Pierce, Torrance, CA US
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20130019633 | METHOD FOR PRODUCTION OF A COMPRESSED NATURAL GAS EQUIVALENT FROM LANDFILL GAS AND OTHER BIOGASES - Biogas is converted to a vehicle fuel equivalent to compressed natural gas high in methane in a simple, low cost process involving steps of refrigeration, non-regenerative activated carbon purification and carbon dioxide removal using low-pressure membrane technology. | 01-24-2013 |
20130060074 | Method for Producing High Purity Biomethane Without Adding Unacceptable Quantities of Moisture - A method for producing high purity biomethane using two non-regenerative media in series to reliably and virtually completely eliminate undesirable impurities from biomethane. The first media in the series is activated carbon, preferably virgin media, produced from coconut shells or coal. The second media in the series is silica gel or other desiccant. Neither material is regenerated; rather, the purity of the biomethane is monitored and when the media is spent, the media is discarded. | 03-07-2013 |
Jeffrey S. Pierce, San Jose, CA US
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20090285372 | SYSTEM AND METHOD FOR PROVIDING AWARENESS OF AND CONTEXT FOR PHONE CONVERSATIONS ACROSS MULTIPLE PERSONAL DEVICES - Disclosed are embodiments of a system and method for automating the exchange of information between the multiple personal computerized devices of an entity so as to provide context for communications, such as incoming and/or outgoing telephone calls, with other entities. The system and method associate one entity with multiple devices. Communications over a device (e.g., one of the various types of telephones) are tracked. Then, for a given communication, an identifier (e.g., a caller ID from an incoming telephone call) is communicated to at least one other device. The other device performs a local and/or internet search for information associated with that particular identifier. The retrieved information is then displayed so as to provide the entity with essentially instantaneous context for the given communication. The system can be implemented using client-server network technology or, alternatively, using point-to-point communication technology. | 11-19-2009 |
20110208717 | CHAFFING SEARCH ENGINES TO OBSCURE USER ACTIVITY AND INTERESTS - A computer program product comprises a computer readable storage medium containing computer code that, when performed by a computer, implements a method for obscuring at least one computer search by a set of users from at least another user, wherein the method includes issuing a plurality of search requests comprised of one or more search requests issued by the set of users, and one or more spurious search requests, to at least one computer search provider; and separating search results received from the at least one computer search provider associated with the plurality of search requests into one or more intended search results in response to the one or more search requests issued by the set of users, and one or more spurious search results in response to the one or more spurious search requests not issued by the set of users. | 08-25-2011 |
Jeffrey S. Pierce, Sunnyvale, CA US
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20140188809 | INTERACTION-BASED MANAGEMENT OF CONTACT ENTRIES - Embodiments of the invention relate to interaction-based management of contact entries. In one embodiment, at least one contact in a set of contacts is determined to be associated with an archiving indicator. The archiving indicator indicates that one or more archiving operations are to be performed on the at least one contact. The set of contacts is associated with a user. At least one archiving threshold associated with the at least one contact is identified based on the determination. A determination is made as to whether the at least one archiving threshold has been satisfied. The at least one contact is archived based on the at least one archiving threshold having been satisfied. | 07-03-2014 |
20140188810 | INTERACTION-BASED MANAGEMENT OF CONTACT ENTRIES - Embodiments of the invention relate to interaction-based management of contact entries. In one embodiment, at least one contact in a set of contacts is determined to be associated with an archiving indicator. The archiving indicator indicates that one or more archiving operations are to be performed on the at least one contact. The set of contacts is associated with a user. At least one archiving threshold associated with the at least one contact is identified based on the determination. A determination is made as to whether the at least one archiving threshold has been satisfied. The at least one contact is archived based on the at least one archiving threshold having been satisfied. | 07-03-2014 |
20140365583 | MANAGING A MESSAGING STATE ACROSS MULTIPLE CLIENTS - Embodiments of the invention relate to managing a messaging state across multiple clients and devices which use respective communications systems. In one embodiment, a plurality of users are connected to multiple messaging communications systems. The multiple messaging communications systems use a plurality of associated messaging clients on each of the users' respective devices, for messaging communications between the users. The users' messaging communications are stored from the multiple messaging communications systems and their respective messaging clients, using a proxy service. A device, of the plurality of messaging clients, being used by a messaging user of the plurality of users is tracked. A current messaging communication of the messaging user from the stored messaging communications is routed to the currently used device, using the proxy service, for maintaining a state of the messaging communications of the users. | 12-11-2014 |
20150052213 | MANAGING CONVERSATIONS, AWARENESS AND AVAILABILITY ON MULTI-DEVICE MESSAGING SYSTEMS BASED ON MODELING DEVICE USAGE OVER TIME - Embodiments of the invention include a system and method for determining availability of a user on a plurality of communication devices includes collecting usage data of the user. An algorithm generates a predictive availability model of a user having a plurality of devices based on previous availability data collected, using a program executable by a processor of a computer. An algorithm prioritizes the devices of the user along with their respective messaging systems, to route a message from a sender to the user based on the predictive availability model, using the program. Routing logic is configured to route the message from the sender to the user based on the prioritization algorithm. | 02-19-2015 |
Jeffrey Scott Pierce, San Jose, CA US
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20120222093 | PARTIAL AUTHENTICATION FOR ACCESS TO INCREMENTAL DATA - Embodiments of the invention relate to partial authentication to access incremental information. An aspect of the invention concerns a method of authorizing access to information that comprises providing an initial segment of a password wherein the password includes password segments each associated with an incremental portion of the information. In response to the initial password segment satisfying an expected value, the method may authorize access to the information portion associated with the initial password segment. The method may authorize access to other information portions associated with subsequent segments of the password in response to the subsequent password segments satisfying respectively expected values. | 08-30-2012 |
Jeffrey Scott Pierce, Sunnyvale, CA US
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20140298347 | COMPUTING SYSTEM WITH RESOURCE MANAGEMENT MECHANISM AND METHOD OF OPERATION THEREOF - A computing system includes: an activity-schedule module configured to identify a future activity estimation for representing an activity occurring after a current time; a usage module, coupled to the activity-schedule module, configured to generate a consumption model associated with the future activity estimation for describing a resource; a model generator module, coupled to the usage module, configured to determine a cost model for evaluating an access location; and a selection module, coupled to the model generator module, configured to determine an optimal access selection based on the cost model and the consumption model for displaying on a device. | 10-02-2014 |
20150094093 | COMPUTING SYSTEM WITH CONFIGURATION UPDATE MECHANISM AND METHOD OF OPERATION THEREOF - A computing system includes: a context module configured to determine a contextual information for representing the contextual information relative to a device; a zone module, coupled to the context module, configured to determine a proximity zone for identifying further devices within the proximity zone relative to the device; a proximate-device module, coupled to the zone module, configured to determine proximate-device identities for identifying the further devices relative to the device; and a configuration transfer module, coupled to the proximate-device module, configured to communicate a transferable configuration setting with a communication unit using the proximate-device identities for updating the device based on the transferable configuration setting and the contextual information for displaying on the device. | 04-02-2015 |
20150095725 | COMPUTING SYSTEM WITH INFORMATION MANAGEMENT MECHANISM AND METHOD OF OPERATION THEREOF - A computing system includes: a control unit configured to: determine a precision level of an entry made to an application, determine an incomplete item based on the precision level failing to meet a precision threshold, and a user interface, coupled to the control unit, configured to display the incomplete item. | 04-02-2015 |
20150145676 | ELECTRONIC SYSTEM WITH DYNAMIC LOCALIZATION MECHANISM AND METHOD OF OPERATION THEREOF - An electronic system includes a storage interface configured to access a kinematic model for representing one or more motions of a carrier; a control unit, coupled to the storage interface, configured to determine an attachment location of an attachable device based on the kinematic model; and generate a device setting based on the attachment location for provisioning the attachable device. | 05-28-2015 |
Joan M. Pierce, San Diego, CA US
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20090264429 | Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase - Certain aryl-hydroxyethylamino-pyrimidine and triazine compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis). Methods of synthesizing such compounds are also disclosed. | 10-22-2009 |
Joan M. Pierce, Lajolla, CA US
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20120095001 | SUBSTITUTED-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONES - The present invention relates to substituted 1,3,8-triazaspiro[4.5]decame-2,4-diones useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions. | 04-19-2012 |
Joel M. Pierce, Wilton, CA US
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20140194635 | Production of Biodiesel and Glycerin from High Free Fatty Acid Feedstocks - A system and method for the conversion of free fatty acids to glycerides and the subsequent conversion of glycerides to glycerin and biodiesel includes the transesterification of a glyceride stream with an alcohol. The fatty acid alkyl esters are separated from the glycerin to produce a first liquid phase containing a fatty acid alkyl ester rich (concentrated) stream and a second liquid phase containing a glycerin rich (concentrated) stream. The fatty acid alkyl ester rich stream is then subjected to distillation, preferably reactive distillation, wherein the stream undergoes both physical separation and chemical reaction. The fatty acid alkyl ester rich stream is then purified to produce a purified biodiesel product and a glyceride rich residue stream. Neutralization of the alkaline stream, formed during the alkali-catalyzed transesterfication process, may proceed by the addition of a mineral or an organic acid. | 07-10-2014 |
Jonathan A. Pierce, Hollywood, CA US
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20110022462 | DIGITAL CINEMA NETWORK SYSTEM AND METHOD FOR TARGETING FILMS AND ADVERTISING - Disclosed herein are systems and methods for the distribution of media content to the public, utilizing an internet community network of subscribers having access to sample content; systems and methods for financing the implementation of digital projection capability in a plurality of theaters; systems and methods for dynamically targeting advertising to an audience based on the brand landscape at a given time in a given place; and systems and methods for progressively encumbering content through licensing as the popularity of content increases. | 01-27-2011 |
Joshua Pierce, La Jolla, CA US
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20110172214 | USE OF TARGETED NITROXIDE AGENTS IN PREVENTING, MITIGATING AND TREATING RADIATION INJURY - Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation. | 07-14-2011 |
Karen A. Pierce, La Mirada, CA US
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20120312762 | Balloon Holder - A holder for a floating balloon having a variety of protrusions or holes form to or through which a floating balloon can be tied, and a slit to allow a first end and a second and to be separated apart so that the holder can be attached to a variety of objects or human body parts. | 12-13-2012 |
Kenneth J. Pierce, Aliso Viejo, CA US
Patent application number | Description | Published |
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20090260423 | Sensors with improved properties - A sensor or a sensor array connected to an electrical measuring apparatus is disclosed. In one embodiment, at least one sensor contains a layer of conductive modified particles which forms an electrical pathway or electrical circuit between two electrodes which are connected to an electrical measuring apparatus. In another embodiment, the first sensor contains at least one region of a nonconducting material and also a region that contains one or more modified particles. The modified particles are preferably conductive. An electrical path exists though the regions of the nonconducting material and the region containing the modified particles. The modified particles are conductive and more preferably are pigment particles such as modified carbon black, wherein the modified particles have attached at least one organic group. Alternatively, or in addition, the modified particle can be an aggregate having a carbon phase and a silicon-containing species phase and/or a metal-containing species phase wherein the aggregate optionally has attached at least one organic group. A sensor array for detecting an analyte in a fluid is also disclosed wherein each sensor emits a different response signature to an analyte wherein at least one of the sensors contains at least the modified particles as described above. Also, the present invention relates to a method for detecting the presence of an analyte in a fluid. The method involves contacting one or more sensors as described above with the analyte to generate a response and detecting the response with a detector that is operatively associated with each sensor in order to detect the presence of an analyte. Other advantages and embodiments are further described. | 10-22-2009 |
Kirsten Pierce, Burlingame, CA US
Patent application number | Description | Published |
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20100015047 | Lung-Expressed Polypeptides - Modulators of phosphatidic acid phosphatase type 2C and other polypeptides, highly expressed in cancers as compared to normal tissues, are provided for treatment of proliferative disorders such as cancer. A method is provided for detecting polypeptides that are overexpressed in cancer, whereby antibodies or binding proteins that specifically recognize these molecules are contacted with a patient's bodily fluid. The method provides an early diagnosis of cancer, and can detect recurrence and metastasis following an initial diagnosis. The invention further provides methods of treating cancer with therapeutic agents directed toward these protein and peptide biomarkers. | 01-21-2010 |
Kristen Pierce, Burlingame, CA US
Patent application number | Description | Published |
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20080254033 | Pharmaceutical Compositions Containing Antagonists to Lrp4, Lrp8 or Megalin for Treatment of Diseases - The present invention provides LRP4, LRP8 and LRP2 (megalin) polypeptides; polynucleotides encoding such; modulators of LRP4, LRP8 and LRP2 activity; and pharmaceutical compositions for the treatment of diseases. Compositions of the invention contain a pharmaceutically acceptable carrier or excipient and at least one modulator that is capable of binding to or interfering with the activity of LRP4, LRP8, LRP2 and active fragments thereof. The invention provides modulators, such as antibodies, RNAi molecules, anti-sense molecules and ribozymes. Additionally, the invention includes methods for the treatment of diseases, such as proliferative diseases and degenerative diseases, and methods of administration of the compositions of the invention. | 10-16-2008 |
20100183620 | COMPOSITIONS AND METHODS FOR REGULATING COLLAGEN AND SMOOTH MUSCLE ACTIN EXPRESSION BY SERPINE2 - The invention encompasses methods and compositions for increasing or decreasing collagen 1A1 expression and/or α-smooth muscle actin expression in lung fibroblasts using SERPINE2 and antagonists of SERPINE2. The invention also encompasses methods and compositions for increasing or decreasing the formation of myofibroblasts. The invention further provides methods and compositions for treatment of lung diseases, such as idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease. | 07-22-2010 |
20150050273 | AFUCOSYLATED ANTI-FGFR2IIIB ANTIBODIES - The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided. | 02-19-2015 |
Laura Pierce, San Diego, CA US
Patent application number | Description | Published |
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20090047243 | COMBINATIONS FOR THE TREATMENT OF B-CELL PROLIFERATIVE DISORDERS - The invention features compositions and methods employing combinations of an A2A receptor agonist and a PDE inhibitor for the treatment of a B-cell proliferative disorder, e.g., multiple myeloma. | 02-19-2009 |
Lawrence K. Pierce, Aromas, CA US
Patent application number | Description | Published |
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20090169687 | Hollow Celery Stick | 07-02-2009 |
20090210960 | Celery Cultivar ADS-16 - A celery cultivar, designated ADS-16, is disclosed. The invention relates to the seeds of celery cultivar ADS-16, to the plants of celery cultivar ADS-16 and to methods for producing a celery plant by crossing the cultivar ADS-16 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-16, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-16 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-16 with another celery cultivar. | 08-20-2009 |
20090260096 | Celery Cultivar ADS-18 - A celery cultivar, designated ADS-18, is disclosed. The invention relates to the seeds of celery cultivar ADS-18, to the plants of celery cultivar ADS-18 and to methods for producing a celery plant by crossing the cultivar ADS-18 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-18, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-18 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-18 with another celery cultivar. | 10-15-2009 |
20090282506 | Celery Cultivar ADS-17 - A celery cultivar, designated ADS-17, is disclosed. The invention relates to the seeds of celery cultivar ADS-17, to the plants of celery cultivar ADS-17 and to methods for producing a celery plant by crossing the cultivar ADS-17 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-17, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-17 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-17 with another celery cultivar. | 11-12-2009 |
20100227032 | Celery Cultivar ADS-15 - A celery cultivar, designated ADS-15, is disclosed. The invention relates to the seeds of celery cultivar ADS-15, to the plants of celery cultivar ADS-15 and to methods for producing a celery plant by crossing the cultivar ADS-15 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-15, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-15 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-15 with another celery cultivar. | 09-09-2010 |
20100227033 | Celery Cultivar ADS-19 - A celery cultivar, designated ADS-19, is disclosed. The invention relates to the seeds of celery cultivar ADS-19, to the plants of celery cultivar ADS-19 and to methods for producing a celery plant by crossing the cultivar ADS-19 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-19, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-19 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-19 with another celery cultivar. | 09-09-2010 |
20100316773 | Hollow-Celery Stick and Celery Pack | 12-16-2010 |
20120244259 | CELERY PACK - A sanitized, ready-to-use and ready-to-eat celery pack is disclosed wherein the package consists of limbs that are from 6- to 18-inches in length and weigh from 0.10 to 11.75 pounds. The limbs are prepared by removing the butt, heart and leaves from celery stalks, cut to lengths from 6 to 18-inches, sorted by length, sanitized and packaged. | 09-27-2012 |
20120255048 | Celery Cultivar ADS-20 - A celery cultivar, designated ADS-20, is disclosed. The invention relates to the seeds of celery cultivar ADS-20, to the plants of celery cultivar ADS-20 and to methods for producing a celery plant by crossing the cultivar ADS-20 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-20, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-20 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-20 with another celery cultivar. | 10-04-2012 |
20120260365 | Celery Cultivar ADS-21 - A celery cultivar, designated ADS-21, is disclosed. The invention relates to the seeds of celery cultivar ADS-21, to the plants of celery cultivar ADS-21 and to methods for producing a celery plant by crossing the cultivar ADS-21 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-21, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-21 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-21 with another celery cultivar. | 10-11-2012 |
20130042368 | CELERY CULTIVAR ADS-22 - A celery cultivar, designated ADS-22, is disclosed. The invention relates to the seeds of celery cultivar ADS-22, to the plants of celery cultivar ADS-22 and to methods for producing a celery plant by crossing the cultivar ADS-22 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-22, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-22 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-22 with another celery cultivar. | 02-14-2013 |
20130055464 | CELERY CULTIVAR ADS-23 - A celery cultivar, designated ADS-23, is disclosed. The invention relates to the seeds of celery cultivar ADS-23, to the plants of celery cultivar ADS-23 and to methods for producing a celery plant by crossing the cultivar ADS-23 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-23, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-23 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-23 with another celery cultivar. | 02-28-2013 |
20130086711 | CELERY CULTIVAR ADS-24 - A celery cultivar, designated ADS-24, is disclosed. The invention relates to the seeds of celery cultivar ADS-24, to the plants of celery cultivar ADS-24 and to methods for producing a celery plant by crossing the cultivar ADS-24 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-24, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-24 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-24 with another celery cultivar. | 04-04-2013 |
20140030389 | STEM CELERY HAVING A HOLLOW PETIOLE | 01-30-2014 |
20150121557 | CELERY CULTIVAR ADS-25 - A celery cultivar, designated ADS-25, is disclosed. The invention relates to the seeds of celery cultivar ADS-25, to the plants of celery cultivar ADS-25 and to methods for producing a celery plant by crossing the cultivar ADS-25 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-25, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-25 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-25 with another celery cultivar. | 04-30-2015 |
20150121558 | CELERY CULTIVAR ADS-26 - A celery cultivar, designated ADS-26, is disclosed. The invention relates to the seeds of celery cultivar ADS-26, to the plants of celery cultivar ADS-26 and to methods for producing a celery plant by crossing the cultivar ADS-26 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-26, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-26 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-26 with another celery cultivar. | 04-30-2015 |
Matthew D. Pierce, Los Angeles, CA US
Patent application number | Description | Published |
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20100292920 | Navigation Services Based on Position Location Using Broadcast Digital Television Signals - A service depends on the location of a device. The device location is determined using DTV signals. More specifically, the device location is determined based on pseudo-ranges between the device and a plurality of digital television (DTV) transmitters and the pseudo-ranges are determined based on broadcast DTV signals received by the device from the DTV transmitters. Examples of DTV signals include the American Television Standards Committee (ATSC) signals, the European Telecommunications Standards Institute Digital Video Broadcasting-Terrestrial (DVB-T) signals and the Japanese Integrated Service Digital Broadcasting-Terrestrial (ISDB-T) signals. | 11-18-2010 |
Matthew Dalton Pierce, Los Angeles, CA US
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20160027260 | Systems and Methods for Creating and Maintaining Real Money Tournaments for Video - By one or more processors of a computing device, receive a player game election of a player, the player game election comprising a skill based video game and one or more player characteristics of the player, determine a first player eligibility of the player to participate in the skill based video game comprising verify the one or more player characteristics, send the first player eligibility to an operator of the skill based video game, receive a list of one or more players that fulfilled a win condition for the skill based video game, determine a second player eligibility to receive a payout based on the list of one or more players that fulfilled the win condition, the first player eligibility, and a player preference for a payout type, and distribute the payout to the one or more players that fulfill the win condition. | 01-28-2016 |
Mike Pierce, Dana Point, CA US
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20130183892 | AUTOMATIC COIN SORTING DEVICE - An automatic coin sorting device is provided. The sorting device may include a housing having a hopper configured for receiving coins, a coin tray coupled to the housing, wherein the coin tray is moveable from a first position to a second position, and a plurality of tubular coin receiving members removably secured to the coin tray, wherein each tubular coin receiving member is configured for receiving a different-sized coin. Each tubular coin receiving member includes an angled opening near one face of the coin receiving member to prevent jamming or back-filling of the coins when the coin receiving member is filled to capacity. | 07-18-2013 |
Pamela Anne Pierce, San Francisco, CA US
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20100029712 | Irrigation solution and method for inhibition of pain, inflammation, spasm and restenosis - A method and solution for perioperatively inhibiting a variety of pain, inflammation, spasm and restenosis processes resulting from cardiovascular or general surgical, therapeutic and diagnostic procedures. The solution preferably includes multiple pain and inflammation inhibitory agents, including at least one local anesthetic agent, and spasm inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. Specific preferred embodiments of the solution of the present invention for use in cardiovascular and general vascular procedures also include anti-restenosis agents. | 02-04-2010 |
Regan A. Pierce, Laguna Niguel, CA US
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20140364864 | FOOT PEDAL SYSTEM AND APPARATUS - A phacoemulsification system and method, and a surgical foot pedal device, system and method. The present invention may include a console comprising a plurality of modes for at least one physically associated surgical instrument, and a foot pedal communicatively associated with said console and suitable for varying ones of the plurality of modes. The foot pedal may include a housing comprising the communicative association, and comprising at least one potentiometer and at least two top switches for the varying of the ones of the plurality of modes, a treadle rotatably mounted within the housing and suitable for depressing the at least one potentiometer, and at least two side switches movably associated with the treadle for the varying of the ones of the plurality of modes. | 12-11-2014 |
Robert Pierce, Danville, CA US
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20090122949 | SYSTEM AND METHOD FOR WEAR LEVELING UTILIZING A RELATIVE WEAR COUNTER - An invention is provided for wear leveling in a non-volatile memory system utilizing relative wear counters to indicate relative levels of wear for each memory block in a non-volatile memory system. Whenever a memory block is erased, the associated relative wear counter is incremented. Then, when any relative wear counter reaches a predetermined limit, the value of the lowest relative wear counter is subtracted from each relative wear counter. Thus, each relative wear counter indicates a relative wear level of the associated memory block relative to other memory blocks. In this manner, the relative wear levels are maintained while reducing the amount of memory needed to for each relative wear counter. | 05-14-2009 |
Robert D. Pierce, Albany, CA US
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20080294481 | Data Management and Processing System for Large Enterprise Model and Method Therefor - A computer system performs data processing using a data organizer which parses a primary set of data into predefined sets of data components according to one or more enterprise models. The sets of data components from the data organizer are respectively stored in multiple data sources. The data components may be stored as a binary file or hierarchical file. A plurality of data processing systems execute the enterprise models. A task manager controls which enterprise model executes on each data processing system. The data processing systems access the data components from the data sources which correspond the executing enterprise model. The data components are sent over dedicated communication channels to the data processing systems. Each data processing system may have a data interface, which is configured to receive data from different sources and convert the data into a standard format. | 11-27-2008 |
Robert H. Pierce, Palo Alto, CA US
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20090011993 | Novel strategies for delivery of active agents using micelles and particles - The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles. | 01-08-2009 |
Robert H. Pierce, La Jolla, CA US
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20150355184 | ANTIBODIES THAT BIND TO HUMAN PROGRAMMED DEATH LIGAND 1 (PD-L1) - The present disclosure provides isolated antibodies that specifically bind to human PD-L1, as well as antigen binding fragments of such antibodies, and kits comprising the anti-PD-L1 antibodies or binding fragments and a set of reagents for detecting a complex of the antibody, or antigen binding fragment thereof, bound to human PD-L1. The antibodies and antigen binding fragments of this disclosure are useful for immunohistochemical detection of human PD-L1 expression in tissue samples. Nucleic acid molecules encoding the antibodies and antigen binding fragments of this disclosure, as well as expression vectors and host cells for expression thereof, are also provided. | 12-10-2015 |
Robert H. Pierce, San Francisco, CA US
Patent application number | Description | Published |
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20150355184 | ANTIBODIES THAT BIND TO HUMAN PROGRAMMED DEATH LIGAND 1 (PD-L1) - The present disclosure provides isolated antibodies that specifically bind to human PD-L1, as well as antigen binding fragments of such antibodies, and kits comprising the anti-PD-L1 antibodies or binding fragments and a set of reagents for detecting a complex of the antibody, or antigen binding fragment thereof, bound to human PD-L1. The antibodies and antigen binding fragments of this disclosure are useful for immunohistochemical detection of human PD-L1 expression in tissue samples. Nucleic acid molecules encoding the antibodies and antigen binding fragments of this disclosure, as well as expression vectors and host cells for expression thereof, are also provided. | 12-10-2015 |
20160084839 | IMMUNOHISTOCHEMICAL ASSAY FOR DETECTING EXPRESSION OF PROGRAMMED DEATH LIGAND 1 (PD-L1) IN TUMOR TISSUE - The present disclosure provides processes for describing and quantifying the expression of human programmed death ligand-1 (PD-L1) in tumor tissue sections as detected by immunohistochemical assay using an antibody that specifically binds to PD-L1. The results generated using these processes have a variety of experimental, diagnostic and prognostic applications. | 03-24-2016 |
20160130574 | METHODS OF MEASURING GENE EXPRESSION IN FACS-SORTED CELLS - Improved methods of measuring gene expression in intracellularly immunostained FACS-sorted cell populations are provided. Exemplary methods involve fixing cells with formalin and permeabilizing with mild detergent in the presence of ribonucleoside vanadyl complex prior to FACS sorting, followed by RNA extraction in the presence of de-crosslinking agents. The resulting RNA is suitable for gene expression analysis. The method allows for analysis of the gene expression pattern specifically associated with any sortable cell population or subpopulation. | 05-12-2016 |
Robert Paul Pierce, Palm Springs, CA US
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20140338142 | ATTACHABLE BRUSH FOR A GOLF SHOE - An attachable brush is configured to accommodate footwear. The attachable brush includes a brush further comprising a brush base mechanically coupled to brush bristles that are configured to clean debris from a golf club. An adjustable bracket is mechanically coupled to the brush. The adjustable bracket has an upper angled member mechanically coupled to a central angled member with a set of grips. The central angled member is mechanically coupled to a lower member. An upper bracket is detachably coupled to the adjustable bracket and further comprising an upper bracket horizontal portion mechanically coupled to an upper bracket vertical portion. The upper bracket is configured to grasp a portion of the footwear and the central angled member is configured to also grip the footwear on an opposite side in order to secure the attachable brush beneath the golf shoe. | 11-20-2014 |
Ryan Pierce, Mountain View, CA US
Patent application number | Description | Published |
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20080215077 | Systems, methods and devices for removing obstructions from a blood vessel - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 09-04-2008 |
20080234706 | Systems, methods and devices for removing obstructions from a blood vessel - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 09-25-2008 |
20100076452 | Systems, methods and devices for removing obstructions from a blood vessel - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 03-25-2010 |
20110137332 | Devices and methods for treating vascular malformations - A device for treating vascular malformations includes a primary coil and secondary windings. The primary coil provides resilience and structural integrity while the secondary windings fill interstitial spaces in the primary coil to isolate the vascular malformation. The device may have increased density along a central portion to isolate the malformation. In another aspect, the device may have a central opening through which embolic materials may be delivered. | 06-09-2011 |
20110166586 | SYSTEMS, METHODS AND DEVICES FOR REMOVING OBSTRUCTIONS FROM A BLOOD VESSEL - A system for removing an obstruction from a blood vessel includes an obstruction engaging element and an expandable capture element. The capture element preferably has a flexible cover and an expandable support structure. The engaging element engages the obstruction and moves the obstruction into the capture element. The capture element protects the obstruction when the obstruction is moved into the catheter. | 07-07-2011 |
20110172699 | Balloon Catheter - This is a balloon catheter having at least two lumens. One of the lumens is a large working lumen. The balloon catheter is especially useful as a guide catheter or micro catheter and may be used in a variety of therapeutic and diagnostic procedures. In particular, it has value in treating neurovascular embolic strokes in combination with other devices which are delivered to the stroke site through that working lumen. The remainder of the lumens typically are used to inflate and to deflate the balloon. | 07-14-2011 |
20110224776 | DEVICES AND METHODS FOR TREATING VASCULAR MALFORMATIONS - A device for treating vascular malformations includes a primary coil and secondary windings. The primary coil provides resilience and structural integrity while the secondary windings fill interstitial spaces in the primary coil to isolate the vascular malformation. The device may have increased density along a central portion to isolate the malformation. In another aspect, the device may have a central opening through which embolic materials may be delivered. | 09-15-2011 |
20120143230 | SYSTEMS, METHODS AND DEVICES FOR REMOVING OBSTRUCTIONS FROM A BLOOD VESSEL - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 06-07-2012 |
20120283760 | SYSTEMS, METHODS AND DEVICES FOR REMOVING OBSTRUCTIONS FROM A BLOOD VESSEL - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 11-08-2012 |
20120310251 | SYSTEMS, METHODS AND DEVICES FOR REMOVING OBSTRUCTIONS FROM A BLOOD VESSEL - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 12-06-2012 |
20130253569 | SYSTEMS, METHODS AND DEVICES FOR REMOVING OBSTRUCTIONS FROM A BLOOD VESSEL - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 09-26-2013 |
20140128894 | SYSTEMS, METHODS AND DEVICES FOR REMOVING OBSTRUCTIONS FROM A BLOOD VESSEL - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 05-08-2014 |
20140135814 | SYSTEMS, METHODS AND DEVICES FOR REMOVING OBSTRUCTIONS FROM A BLOOD VESSEL - Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. | 05-15-2014 |
Ryan K. Pierce, San Jose, CA US
Patent application number | Description | Published |
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20140345623 | NASAL DEVICES WITH VARIABLE LEAK PATHS, NASAL DEVICES WITH ALIGNERS, AND NASAL DEVICES WITH FLAP VALVE PROTECTORS - Improved passive resistance nasal devices for treating a patient (and particularly, but not exclusively, a sleeping patient) that inhibit exhalation more than inhalation. For example, described herein are passive-resistance nasal devices having a variable sized opening leak path that change the size of the leak path opening depending on the pressure extended across the nasal device. Also described herein are passive nasal devices including a deployable insertion guide member. Also described herein are passive nasal devices including an extension member to hold the airflow resistor portion of the nasal device slightly apart from the subject's nose, even as the nasal device itself may be secured against the nose or nostril openings. Methods of operating these nasal devices and methods of treating patients using these devices are also described. | 11-27-2014 |
Ryan K. Pierce, San Francisco, CA US
Patent application number | Description | Published |
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20110218451 | NASAL DEVICES, SYSTEMS AND METHODS - Described herein are passive nasal device having a resistance to exhalation that is greater than the resistance to inhalation. Also described are devices, methods and systems for sensing and measuring intranasal pressure when a subject is wearing a passive nasal respiratory device that is configured to inhibit exhalation more than inhalation. Also described are adapters for nasal devices and methods of using a nasal device adapter. Adapters may be used so that a passive nasal device may be applied indirectly in communication with a subject's nose; in some variations this may allow the passive nasal device to be re-used. Also described herein are nasal devices having a billowing airflow resistor that is configured to have a greater resistance to exhalation than to inhalation. The billowing airflow resistor typically includes a first layer that is adjacent to a second layer; the first layer is flexible and billows opens during inhalation so that the first layer remains separated from the second layer, but remains substantially parallel to the second layer. During exhalation, the first layer collapses back down against the second layer. Additional passive nasal devices, systems and methods of using them are also described. | 09-08-2011 |
Ryan K. Pierce, Mountain View, CA US
Patent application number | Description | Published |
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20140107575 | Balloon Catheter - This is a balloon catheter having at least two lumens. One of the lumens is a large working lumen. The balloon catheter is especially useful as a guide catheter or micro catheter and may be used in a variety of therapeutic and diagnostic procedures. In particular, it has value in treating neurovascular embolic strokes in combination with other devices which are delivered to the stroke site through that working lumen. The remainder of the lumens typically are used to inflate and to deflate the balloon. | 04-17-2014 |
Ryan Kendall Pierce, San Francisco, CA US
Patent application number | Description | Published |
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20090050144 | ADHESIVE NASAL RESPIRATORY DEVICES - Whole-nose nasal respiratory devices and methods of making and using whole-nose nasal respiratory devices are described and illustrated herein. These devices are typically configured to be adhesively secured to a subject so that they engage both of the subject's nostrils and allow airflow from both nostrils to communicate with an airflow resistor. The airflow resistor is configured so that it inhibits exhalation through the nostrils more than it inhibits inhalation through the nostrils. | 02-26-2009 |
20090188493 | NASAL DEVICES - Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described. | 07-30-2009 |
20100326447 | NASAL RESPIRATORY DEVICES FOR POSITIVE END-EXPIRATORY PRESSURE - Described herein are nasal respiratory devices, in particular, nasal respiratory devices configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device. PEEP devices may have a threshold pressure for opening during expiration. In some variations, these devices have a threshold pressure for closing during expiration. | 12-30-2010 |
20110067709 | NASAL RESPIRATORY DEVICES - Described herein are nasal respiratory devices and methods for treating a variety of medical diseases including snoring and steep apnea through the use of such devices. In general, these devices include an airflow resistor, such as a flap valve and a holdfast for securing the device in communication with the subject's nasal cavity. The devices may be configured to include leak paths to regulate the expiratory pressure when worn by a subject. Methods for using these devices may include securing a device over or at least partially within (or both of) a subject's nasal cavities. | 03-24-2011 |
20110240038 | NASAL DEVICES - Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described. | 10-06-2011 |
20120055488 | ADHESIVE NASAL RESPIRATORY DEVICES - Whole-nose nasal respiratory devices and methods of making and using whole-nose nasal respiratory devices are described and illustrated herein. These devices are typically configured to be adhesively secured to a subject so that they engage both of the subject's nostrils and allow airflow from both nostrils to communicate with an airflow resistor. The airflow resistor is configured so that it inhibits exhalation through the nostrils more than it inhibits inhalation through the nostrils. | 03-08-2012 |
20160128863 | NASAL RESPIRATORY DEVICES - Devices for altering the flow of air in a respiratory cavity such as the nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical disorders, including snoring and sleep apnea. The devices are typically removable devices that may be placed in both nostrils to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. The nasal devices may also increases patency of the nares. Any of these devices may be configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device. | 05-12-2016 |
Skip Pierce, Westlake Village, CA US
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20100285925 | DANCE PAD - A dance pad having a plurality of conductive panels and incorporating a design which prevents electrostatic discharge from damaging electrical circuitry is disclosed. The dance pad provides the user with a tactile responsive feel, due to the use of resilient spacers and has a tapered perimeter to prevent tripping. The dance pad further incorporates a five handle perimeter design and a means for providing performance feedback to the user which can be audio, visual or vibrational. | 11-11-2010 |
Stephen Pierce, Milpitas, CA US
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20140379760 | SINGLE PAGE FORUM VIEWS - Managing communications relationships may be accomplished by organizing a plurality of information elements and a plurality of users into a forum, with the forum being a virtual data structure organizing a plurality of single page views. Each single page view is organized into columns, with each column having a home row, a header row, and an action row. The header row indicates a title of the column for each of the columns of a single page view, and the action row indicates one or more commands available for execution for the each column of the single page view. The home row is the same for every column of each of the single page views and includes a selectable area that, upon selection by a user, navigates to a single page view associated with a home page view. Actions may be performed on information elements in columns of selected single page views. | 12-25-2014 |
Stephen J. Pierce, Milpitas, CA US
Patent application number | Description | Published |
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20140169554 | SYSTEM, PROCESSING DEVICE, COMPUTER PROGRAM AND METHOD, TO TRANSPARENTLY ENCRYPT AND STORE DATA OBJECTS SUCH THAT OWNERS OF THE DATA OBJECT AND PERMITTED VIEWERS ARE ABLE TO VIEW DECRYPTED DATA OBJECTS AFTER ENTERING USER SELECTED PASSWORDS - A cryptographic system makes everyday data objects, such as a document or conversation, unreadable to anyone other than the owner or those currently having permission to access the data objects. The cryptographic system is transparent by requiring no additional effort on the part of any user in the encryption/decryption process other than entering a user identifier and password. Each document is encrypted with a unique encryption key. Changes to data object access permissions are immediately honored and enforced by enabling or disabling access to certain decryption keys. Decryption of data objects requires information known only to the owner of the data object or those permitted to access the data object. This decryption information is not stored anywhere in the system. | 06-19-2014 |
20150074410 | SYSTEM, PROCESSING DEVICE, COMPUTER PROGRAM AND METHOD, TO TRANSPARENTLY ENCRYPT AND STORE DATA OBJECTS SUCH THAT OWNERS OF THE DATA OBJECT AND PERMITTED VIEWERS ARE ABLE TO VIEW DECRYPTED DATA OBJECTS AFTER ENTERING USER SELECTED PASSWORDS - A cryptographic system makes everyday data objects, such as a document or conversation, unreadable to anyone other than the owner or those currently having permission to access the data objects. The cryptographic system is transparent by requiring no additional effort on the part of any user in the encryption/decryption process other than entering a user identifier and password. Each document is encrypted with a unique encryption key. Changes to data object access permissions are immediately honored and enforced by enabling or disabling access to certain decryption keys. Decryption of data objects requires information known only to the owner of the data object or those permitted to access the data object. This decryption information is not stored anywhere in the system. | 03-12-2015 |
Steve Pierce, Pleasanton, CA US
Patent application number | Description | Published |
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20110281159 | MULTI-LAYER COATINGS FOR BIPOLAR RECHARGEABLE BATTERIES WITH ENHANCED TERMINAL VOLTAGE - A method for producing a multi-layer bipolar coated cell according to one embodiment includes applying a first active cathode material above a substrate to form a first cathode; applying a first solid-phase ionically-conductive electrolyte material above the first cathode to form a first electrode separation layer; applying a first active anode material above the first electrode separation layer to form a first anode; applying an electrically conductive barrier layer above the first anode; applying a second active cathode material above the anode material to form a second cathode; applying a second solid-phase ionically-conductive electrolyte material above the second cathode to form a second electrode separation layer; applying a second active anode material above the second electrode separation layer to form a second anode; and applying a metal material above the second anode to form a metal coating section. In another embodiment, the anode is formed prior to the cathode. Cells are also disclosed. | 11-17-2011 |
20140170475 | ELECTRODES, ELECTROCHEMICAL CELLS, AND METHODS OF FORMING ELECTRODES AND ELECTROCHEMICAL CELLS - Electrodes and methods of forming electrodes are described herein. The electrode can be an electrode of an electrochemical cell or battery. The electrode includes a current collector and a film in electrical communication with the current collector. The film may include a carbon phase that holds the film together. The electrode further includes an electrode attachment substance that adheres the film to the current collector. | 06-19-2014 |
20140295290 | ELECTRODES, ELECTROCHEMICAL CELLS, AND METHODS OF FORMING ELECTRODES AND ELECTROCHEMICAL CELLS - Electrodes and methods of forming electrodes are described herein. The electrode can be an electrode of an electrochemical cell or battery. The electrode includes a current collector and a film in electrical communication with the current collector. The film may include a carbon phase that holds the film together. The electrode further includes an electrode attachment substance that adheres the film to the current collector. | 10-02-2014 |
Terry Pierce, Rancho Cucamonga, CA US
Patent application number | Description | Published |
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20150356527 | APPARATUS AND METHODS FOR CONDUCTING ATM TRANSACTIONS - Apparatus and methods | 12-10-2015 |