Patent application number | Description | Published |
20090193789 | VARIABLE AREA FAN NOZZLE THRUST REVERSER - A nozzle for use in a gas turbine engine includes nozzle doors coupled with a fan nacelle wherein the nozzle doors move in unison between a plurality of positions to influence a bypass airflow through a fan bypass passage. A linkage connects the nozzle doors and an actuator. A louver section coupled with the linkage moves in unison with the nozzle doors between a plurality of louver positions to direct a portion of the bypass airflow in a selected direction. | 08-06-2009 |
20100043394 | GAS TURBINE ENGINE FAN VARIABLE AREA NOZZLE WITH SWIVALABLE INSERT SYSTEM - A turbofan engine ( | 02-25-2010 |
20100257841 | VARIABLE AREA FAN NOZZLE AND THRUST REVERSER - A nozzle for use in a gas turbine engine includes a nozzle door having a first end, a second end opposed from the first end, and a pivot between the first end and the second end. A linkage connects to the nozzle door and to an actuator. The actuator is selectively operative to move the linkage to in turn move the nozzle door about the pivot between a plurality of positions, such as a stowed position, an intermediate position, and a thrust reverse position, to influence a bypass airflow through a fan bypass passage. | 10-14-2010 |
20120005999 | VARIABLE AREA FAN NOZZLE AND THRUST REVERSER - An example nozzle for use in a gas turbine engine includes a nozzle door having a first end, a second end opposed from the first end, and a first pivot on the door between the first and second ends. A linkage connects to the nozzle door and to an actuator. The actuator is selectively operative to move the linkage about a second pivot to in turn move the nozzle door about the first pivot between a plurality of positions, such as stowed, intermediate, and thrust reverse positions to influence bypass airflow through a fan bypass passage. The fan bypass passage has a radially outward side defined by a nacelle in at least one position. At least a portion of the nozzle door is radially outward of the nacelle and includes a lip extending from the nozzle door between the first pivot and one of the first end and second end. | 01-12-2012 |
20120137655 | VARIABLE AREA FAN NOZZLE THRUST REVERSER - A nozzle for use in a gas turbine engine includes nozzle doors coupled with a fan nacelle wherein the nozzle doors move in unison between a plurality of positions to influence a bypass airflow through a fan bypass passage. A linkage connects the nozzle doors and an actuator. A louver section coupled with the linkage moves in unison with the nozzle doors between a plurality of louver positions to direct a portion of the bypass airflow in a selected direction. | 06-07-2012 |
20120325930 | VARIABLE AREA FAN NOZZLE AND THRUST REVERSER - An example nozzle for use in a gas turbine engine includes a nozzle door having a first end, a second end opposed from the first end, and a first pivot on the door between the first and second ends. A linkage connects to the nozzle door and to an actuator. The actuator is selectively operative to move the linkage about a second pivot to in turn move the nozzle door about the first pivot between a plurality of positions, such as stowed, intermediate, and thrust reverse positions to influence bypass airflow through a fan bypass passage. The fan bypass passage has a radially outward side defined by a nacelle in at least one position. At least a portion of the nozzle door is radially outward of the nacelle and includes a lip extending from the nozzle door between the first pivot and one of the first end and second end. | 12-27-2012 |
20130047579 | GAS TURBINE ENGINE FAN VARIABLE AREA NOZZLE WITH SWIVABLE INSERT SYSTEM - An example nacelle assembly for a gas turbine engine includes a nacelle defined about an axis and defining a boundary of a fan bypass flow path. A fan variable area nozzle includes a plurality of inserts movably mounted to said nacelle. Each of the multiple of inserts is located at a circumferential position about the nacelle. The multiple of inserts are each independently moveable into the fan bypass flow path relative the nacelle to selectively vary a fan nozzle exit area. | 02-28-2013 |
Patent application number | Description | Published |
20090191610 | Microorganisms With Increased Efficiency for Methionine Synthesis - The present invention relates to methods for the production of microorganisms with increased efficiency for methionine synthesis, microorganisms with increased efficiency for methionine synthesis, and methods for determining the optimal metabolic flux for organisms with respect to methionine synthesis. | 07-30-2009 |
20090298136 | Methionine producing recombinant microorganisms - This invention relates to methionine producing recombinant microorganisms. Specifically, this invention relates to recombinant strains of | 12-03-2009 |
20090298137 | MICROORGANISM AND PROCESS FOR THE PREPARATION OF L-METHIONINE - The present invention relates to microorganisms and processes for the efficient preparation of L-amino acids such as L-methionine. In particular, the present invention relates to microorganisms and processes in which the formation and/or accumulation of homolanthionine in the methionine pathway is reduced and/or prevented. | 12-03-2009 |
20120220000 | ENGINEERING MICROBES FOR EFFICIENT PRODUCTION OF CHEMICALS - This present invention relates to production of chemicals from microorganisms that have been genetically engineered and metabolically evolved. Improvements in chemical production have been established, and particular mutations that lead to those improvements have been identified. Specific examples are given in the identification of mutations that occurred during the metabolic evolution of a bacterial strain genetically engineered to produce succinic acid. This present invention also provides a method for evaluating the industrial applicability of mutations that were selected during the metabolic evolution for increased succinic acid production. This present invention further provides microorganisms engineered to have mutations that are selected during metabolic evolution and contribute to improved production of succinic acid, other organic acids and other chemicals of commercial interest. | 08-30-2012 |
20150044755 | PRODUCTION OF MUCONIC ACID FROM GENETICALLY ENGINEERED MICROORGANISMS - This present invention is in the field of producing renewable chemical feedstocks using biocatalysts that have been genetically engineered to increase their ability to convert renewable carbon resources into useful compounds. More specifically, the present invention provides a process for producing muconic acid form renewable carbon resources using a genetically modified organism. | 02-12-2015 |
20150240270 | PRODUCTION OF ORGANIC ACIDS BY FERMENTATION AT LOW PH - This invention relates to the biosynthesis of organic acids in genetically modified microorganisms. More specifically, this invention provides genetically modified microorganisms that are particularly tolerant to organic acids at low pH and are capable of producing organic acids by fermentation at low pH. | 08-27-2015 |
Patent application number | Description | Published |
20130143880 | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 - The present invention is directed to benzimidazolone derivatives which are positive allosteric modulators of the mGluR | 06-06-2013 |
20130203756 | ISOINDOLINE PDE10 INHIBITORS - The present invention is directed to isoindolinone compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction. | 08-08-2013 |
20130210768 | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 - The present invention is directed to 5-substituted 1,3-dihydro-2H-imidazo[4,5-b]pyridine-2-one derivatives which are positive allosteric modulators of the mGluR2 receptor, useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 receptor is involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved, such as schizophrenia. | 08-15-2013 |
20140303143 | BENZOXAZOLINONE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS - Disclosed are compounds of Formula (A) or a salt thereof, wherein “Het”, R | 10-09-2014 |
20140350002 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES - The present invention is directed to imidazopyridin-2-one derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR | 11-27-2014 |
20150252034 | BENZOXAZOLINONE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS - Disclosed are compounds of Formula A: Formula A, or a salt thereof, wherein “Het”, R | 09-10-2015 |
20150284389 | N-SUBSTITUTED INDAZOLE SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS - Disclosed are compounds of Formula A | 10-08-2015 |
Patent application number | Description | Published |
20090281180 | Method for enhancing the DNA repair process, treating disorders associated with the DNA repair process, enhancing antitumor response and treating disorders associated with anti-tumor response in mammals by administering purified quinic acid and/or carboxy alkyl ester - For use in mammals, methods for enhancing the DNA repair process, treating disorders associated with the DNA repair process, enhancing anti-tumor response and treating disorders associated with anti-tumor response. The methods generally comprise non-topical administration of purified, isolated quinic acid alkyl acid or a carboxy alkyl ester with a non-toxic carrier or diluent. | 11-12-2009 |
20090298939 | Method of preparation and composition of a water soluble extract of the bioactive component of the plant species Uncaria for enhancing immune, anti-inflammatory, anti-tumor and DNA repair processes of warm blooded animals - The disclosure provides a method for isolating the bioactive component of the water-soluble extract of | 12-03-2009 |
20100215768 | NUTRITIONAL SUPPLEMENT - A nutritional supplement includes elements having been shown to enhance DNA repair or reduce DNA damage by different molecular mechanisms while excluding other bioactive nutrient agents which compete with any of the elements known modes of action. The supplement includes a resveratrol, a carotenoid, a nicotinamide, a dimethylaminoethanol, a zinc source, and a quinic acid analog. The supplement is administered daily in dosages in excess of normal dietary levels. The supplement improves resistance to DNA damage, enhances DNA repair capacity in tissues including skin, and stimulates immune cellular function. This was accomplished by reducing metabolic competition between DNA repair bioactive components that was in turn paralleled by enhancement of thirst quenching properties in aqueous formulations. | 08-26-2010 |
20110245337 | METHOD FOR ENHANCING THE DNA REPAIR PROCESS, TREATING DISORDERS ASSOCIATED WITH THE DNA REPAIR PROCESS, ENHANCING ANTITUMOR RESPONSE AND TREATING DISORDERS ASSOCIATED WITH ANTI-TUMOR RESPONSE IN MAMMALS BY ADMINISTERING PURIFIED QUINIC ACID AND/OR CARBOXY ALKYL ESTER - For use in mammals, methods for enhancing the anti-tumor response and treating disorders associated with anti-tumor response. The methods generally comprise non-topical administration of purified, isolated quinic acid alkyl acid or a carboxy alkyl ester with a non-toxic carrier or diluent. | 10-06-2011 |
20110263706 | METHOD FOR ENHANCING THE DNA REPAIR PROCESS, TREATING DISORDERS ASSOCIATED WITH THE DNA REPAIR PROCESS, ENHANCING ANTITUMOR RESPONSE AND TREATING DISORDERS ASSOCIATED WITH ANTI-TUMOR RESPONSE IN MAMMALS BY ADMINISTERING PRUIFIED QUINIC ACID AND/OR CARBOXY ALKYL ESTER - The disclosure provides a method for isolating the bioactive component of the water-soluble extract of | 10-27-2011 |