Patent application number | Description | Published |
20090012425 | Apparatus and Method for Collecting a Sample of Material - A sample acquisition device includes a hollow shaft and a porous medium. The hollow shaft includes a proximal end, a distal end, and a sidewall extending between the proximal end and the distal end. The sidewall of the hollow shaft includes a plurality of openings adjacent the distal end of the hollow shaft. The porous medium is attached to the distal end of the hollow shaft and at least a part of the porous medium is positioned over the plurality of openings. | 01-08-2009 |
20090030341 | SAMPLE RELEASE SYSTEM - Devices to process a sample are configured to releasably attach a sample acquisition device to a drive mechanism that provides rotational and/or vibrational motion to the sample acquisition device. The devices can be used in sample processing methods to dislodge sample materials from the sample acquisition device. Sample processing methods using rotational or vibrational motion may further include the use of a liquid medium into which the sample is released. Sample processing methods may further include the detection of an analyte in the sample. | 01-29-2009 |
20090162902 | ANTIBODY WITH PROTEIN A SELECTIVITY - Monoclonal antibodies, and antigen binding fragments thereof, which bind to Protein A of | 06-25-2009 |
20090181469 | METHOD OF ENHANCING SIGNAL DETECTION OF CELL-WALL COMPONENTS OF CELLS - The invention relates to methods of enhancing signal detection of components of cell walls, wherein the methods involve lysing cells to form cell-wall fragments and analyzing the cell-wall fragments. | 07-16-2009 |
20100047252 | ANTIBODY WITH PROTEIN A SELECTIVITY - Monoclonal antibodies, and antigen binding fragments thereof, which bind to Protein A of | 02-25-2010 |
20100062418 | INACTIVATED AND DRIED BIOLOGICAL PREPARATIONS - In one aspect, the present invention provides biological sample that includes a dry preparation comprising a stabilizer and stabilized, inactivated biological material. In certain embodiments, the biological material may be heat inactivated and/or heat dried. In another aspect, the present invention provides a method of making a dried biological preparation. Generally, the method includes collecting a sample of biological material, inactivating the biological material, suspending the sample in a volume of a stabilizer and allowing the stabilizer to dry. In certain embodiments, the biological material may be heat inactivated and/or heat dried. | 03-11-2010 |
20100099115 | SYSTEMS AND METHODS FOR PREPARING AND ANALYZING SAMPLES - The invention relates to systems and methods for preparing and analyzing samples (e.g., mucosal samples) for a microorganism of interest. In particular, the systems and methods are useful for detecting one or more analytes characteristic of a microorganism (i.e., microbe) of interest, such as components of cell walls that are characteristic of a microbe, particularly | 04-22-2010 |
20100129837 | METHODS OF CAPTURING BACTERIAL WHOLE CELLS AND METHODS OF ANALYZING SAMPLES FOR BACTERIA - In certain embodiments, the invention relates to methods of capturing bacterial whole cells that includes the use of two or more antibodies having antigenic specificities for two or more distinct analytes characteristic of the specific bacterium. In certain embodiments, the invention relates to methods of analyzing a sample for a bacterium of interest. In particular, the methods are useful for detecting one or more analytes characteristic of a bacterium of interest, such as components of cell walls that are characteristic of a bacterium, particularly | 05-27-2010 |
20100317021 | FLUIDIC ANTIBODY-CONTAINING DEVICES AND METHODS - The invention relates to devices and methods for analyzing a sample (and preferably preparing a sample), which is particularly used in analysis, such as analysis of a sample for a bacterium of interest. | 12-16-2010 |
20110091903 | METHOD OF ANALYZING A SAMPLE FOR A BACTERIUM USING DIACETYLENE-CONTAINING POLYMER SENSOR - The invention relates to methods of analyzing a sample for a bacterium of interest. In particular, the methods involve an initial capture process that includes the use of one or more antibodies having antigenic specificities for one or more distinct analytes characteristic of the specific bacterium. After initial capture of a specific bacterium, techniques of analyzing involve colorimetric techniques, particularly using colorimetric sensors that include polydiacetylene (PDA) materials. | 04-21-2011 |
20110097814 | DETECTION DEVICES AND METHODS - The application discloses embodiments of detection devices including a sensor component in a flow path between a first flow path portion and a second flow path portion. In embodiments described, the sensor component includes a receptor in a polymerized composition. The receptor is configured to bind with an analyte in a test sample. Upon binding the sensor component undergoes a detectable change in response to interaction of the analyte with the receptor. | 04-28-2011 |
20110146419 | SAMPLE ACQUISITION DEVICE - A sample acquisition device includes a capillary array configured to draw in a sample and retain the sample by capillary action. The capillary array may be coupled to an elongated member, such as a stem or a hollow tube, which defines a longitudinal axis extending in a first direction. In some embodiments, the capillary array defines a major sample acquisition surface that extends in a second direction different than the first direction. A ratio of the major sample acquisition surface area to maximum volume retained by the capillary array may be selected to minimize physical binding between the capillary array and sample. In some embodiments, the device may include a feedback mechanism to indicate the relative pressure applied to a sample source with the sample acquisition device. In addition, in some embodiments, the sample acquisition device may include a suction source to help draw the sample into the capillary array. | 06-23-2011 |
20110171683 | METHODS AND COMPOSITIONS FOR ENUMERATING ANTIBIOTIC-RESISTANT MICROORGANISMS - A thin film culture device for detection of antibiotic-resistant microorganisms is provided. The device can include indicators to differentiate staphylococcal from non-staphylococcal microorganisms. Methods of use include detecting or enumerating antibiotic-resistant microorganisms. The methods further include obtaining a differential count of staphylococcal and non-staphylococcal microorganisms. | 07-14-2011 |
20110177523 | METHODS OF ANALYZING SAMPLES FOR BACTERIA USING WHOLE CELL CAPTURE AND ATP ANALYSIS - The invention relates to methods of capturing bacterial whole cells that includes the use of one or more antibodies having antigenic specificities for one or more distinct analytes characteristic of the specific bacterium, followed by analyzing the target whole cells using a direct or indirect ATP assay. | 07-21-2011 |
20110179887 | SAMPLE ACQUISITION DEVICE - A sample acquisition device includes a body comprising a plurality of sample acquisition regions defined by at least a first wall and a second wall oriented nonparallel to the first wall. In some embodiments, the body defines a plurality of apertures that define a plurality of sample acquisition regions. In other embodiments, the walls extend from the body, and the sample acquisition regions are defined between the walls. The sample acquisition regions may be configured in some embodiments such that a user may acquire a sample by rotating the body in a first direction relative to a sample source and may release the sample by rotating the body in a second direction that is substantially opposite to the first direction. When rotated in the first direction, at least one of the first or second walls defines a surface that is inclined into a sample acquisition region. | 07-28-2011 |
20110244511 | METHODS AND ARTICLES FOR DETECTING HEMOLYTIC MICROORGANISMS - A thin film culture plate device useful for detecting hemolysin-producing microorganisms is included. The device can further include selective agents and/or indicators to differentiate groups or species microorganisms. Methods of use include detecting or enumerating hemolysin-producing microorganisms. | 10-06-2011 |
20110294109 | METHODS FOR DETECTING AN ANALYTE - Methods of decreasing non-specific binding in solid phase assays for an analyte are disclosed. In the methods, the solid phase apparatus (lateral flow solid phase apparatus or capillary flow solid phase apparatus) is subjected to elevated heat. The elevated heat can be applied subsequent to application of a test sample to the solid phase apparatus. | 12-01-2011 |
20120028251 | METHODS AND ARTICLES FOR DETECTING DEOXYRIBONUCLEASE ACTIVITY - The disclosure provides articles and methods useful for detecting a discrete source of DNase activity. DNase-producing microorganisms can be detected. The device can further include selective agents and/or indicators to differentiate groups or species microorganisms. Methods of use include detecting or enumerating DNase-producing microorganisms. | 02-02-2012 |
20120094327 | DETECTION OF ACID-PRODUCING BACTERIA - The disclosure provides culture devices and methods useful for detecting acid-producing bacteria in a sample. The devices include a nutrient medium and a pH indicator to detect and differentiate acid-producing microorganisms, such as lactic acid bacteria. Methods of use include detecting or enumerating acid-producing microorganisms. The methods further provide for the detection of gas-producing acid-producing bacteria. | 04-19-2012 |
20120149884 | SPECIFIC ANTIBODY SELECTION BY SELECTIVE ELUTION CONDITIONS - Methods for preparing high avidity anti-antigen polyclonal antibody preparations by antigen affinity column purification and high avidity anti-antigen polyclonal antibody preparations are described. | 06-14-2012 |
20130266955 | EFFERVESCENT COMPOSITIONS AND USES THEREOF - A latent effervescent body comprising a selective agent is disclosed. A method of using the latent effervescent body in a method to selectively enrich a target microorganism is also disclosed. The method comprises providing a sample, a culture medium, and the latent effervescent body. The method further comprises contacting the sample, the culture medium, and the latent effervescent body under conditions to facilitate growth of the target microorganism. The method further comprises releasing the selective agent from the latent effervescent body. Optionally, the method includes detecting a microorganism. | 10-10-2013 |
20130273598 | ARTICLES AND METHOD FOR DETECTING A TARGET MICROORGANISM - A method of detecting a target microorganism is disclosed. The method comprises providing a culture device with a selective culture medium and a detection article comprising a first indicator system. The selective culture medium facilitates the growth of an indicator microorganism. When an indicator microorganism is detected in a sample contacted with the culture medium, the detection article is contacted with the culture medium to detect the target microorganism. | 10-17-2013 |
20130344488 | FILTRATION METHODS AND DEVICES - A method of filtering a liquid sample that includes passing a sample comprising at least one biological organism through a filter membrane at a passive water volume flux of at least 10 L/m | 12-26-2013 |
20140087406 | SALMONELLA DETECTION ARTICLES AND METHODS OF USE - An article for detecting | 03-27-2014 |
20140356888 | METHOD OF DETECTING A SALMONELLA MICROORGANISM - A method of detecting a | 12-04-2014 |
20150031075 | METHOD OF DETECTING A SALMONELLA MICROORGANISM - A composition is provided for detecting a | 01-29-2015 |
20150050642 | METHODS AND ARTICLES FOR DETECTING DEOXYRIBONUCLEASE ACTIVITY - The disclosure provides articles and methods useful for detecting a discrete source of DNase activity. DNase-producing microorganisms can be detected. The device can further include selective agents and/or indicators to differentiate groups or species microorganisms. Methods of use include detecting or enumerating DNase-producing microorganisms. | 02-19-2015 |