Patel, Gujarat
Ajay Mangubhai Patel, Gujarat IN
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20090182148 | PROCESS FOR THE MANUFACTURE OF MONTELUKAST SODIUM - An improved process for the manufacture of 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid, sodium salt [montelukast sodium(I)]. It consists of converting a vital intermediate 1-(mercaptomethyl)-cyclopropane acetic acid of formula IX, to a quaternary ammonium salt of formula X, using a suitable base in a suitable solvent at 0° C. to 50° C. followed by monometalation to provide an intermediate of formula XI and subsequent condensation of XI with 2-[2-[3-(S)-[3-[2-(7-chloro-2-quinolinyl)-ethenyl]phenyl]-3-methanesulphonyloxypropyl]phenyl]-2-propanol at 0 to −50° C. to afford 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid as the quaternary ammonium salt which is filtered, purified by crystallization from a suitable solvent and finally treated with a sodium base in a suitable solvent to generate montelukast sodium which is isolated by trituration with an antisolvent. The invention provides a convenient process for preparing montelukast sodium (I) in good yields and purities. | 07-16-2009 |
20090281323 | PROCESS FOR THE MANUFACTURE OF MONTELUKAST SODIUM - Process for the manufacture of 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid, sodium salt [montelukast sodium (I)] consisting of: i. Converting methyl 1-(mercaptomethyl)-cyclopropaneacetate to a metal salt (X) using a metal hydroxide, ii. Subjecting the metal salt (X) to monometallation to provide a dimetallide (XI). iii. Converting a diol of formula (II) to a mesylate of formula (III) and reacting (III) in situ with (XI) affordin the metal salt of 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid. iv. Reacting the metal salt in-situ with a base and purifying to afford an amine salt (XII). v. Treating (XII) with a sodium base and precipitating out montelukast sodium (I). | 11-12-2009 |
Anant M. Patel, Gujarat IN
Dhimant Jasubhai Patel, Gujarat IN
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20100274014 | PROCESS FOR MANUFACTURING ROSUVASTATIN POTASSIUM AND CRYSTALLINE AND AMORPHOUS FORMS THEREOF - A process of manufacturing of Rosuvastatin Potassium of formula (I) | 10-28-2010 |
20130158263 | INTERMEDIATES FOR THE PREPARATION OF HMG COA REDUCTASE INHIBITORS AND PROCESSES FOR THE PREPARATION THEREOF - A compound of Formula (1), is disclosed | 06-20-2013 |
Dinesh Ramanlal Patel, Gujarat IN
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20110021634 | PROCESSES FOR PREPARING METFORMIN HYDROCHLORIDE - A process for reducing dimethylamine content in metformin hydrochloride is disclosed. The process comprises: | 01-27-2011 |
Gautam D. Patel, Gujarat IN
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20100240709 | Sulfoximine Derivatives as p38 MAP Kinase Inhibitors - The present invention relates to novel compounds of general formula (I), their regioisomers, tautomeric forms, novel intermediates involved in their synthesis, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula (I), their regioisomers, their tautomeric forms, their pharmaceutically acceptable salts pharmaceutical compositions containing them, and novel intermediates involved in their synthesis. | 09-23-2010 |
Hasmukh Mathurbhai Patel, Gujarat IN
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20090175935 | PHARMACEUTICAL COMPOSITIONS OF DULOXETINE - The present invention relates to solid oral pharmaceutical compositions of duloxetine, process for preparing such compositions and method of using such compositions. Preferably, the invention relates to a delayed release composition of duloxetine comprising a core comprising duloxetine, optional separating coat and an enteric coat, wherein the enteric coat comprises methacrylic acid copolymer. | 07-09-2009 |
Hima Patel, Gujarat IN
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20100246926 | SYSTEM AND METHOD FOR DISTINGUISHING BETWEEN BIOLOGICAL MATERIALS - The invention provides a method for distinguishing biological materials. The method provides: providing at least one segmented image of at least two cells; applying a distance transform to the at least one segmented image of the confluent cells; applying a region growing technique to the distance transform of the at least one segmented image to form a region grown image, wherein a plurality of regions are formed in the at least one segmented image; assigning at least one label to at least one of the plurality of regions of the at least one segmented image of the confluent cells; applying a merging technique to at least two of the plurality of regions if it is determined that at least two of the plurality of regions are neighboring regions; determining whether to assign a same label to the neighboring regions or retain existing labels; and merging the neighboring regions of the region grown image if labels are changed to form at least one image of at least one cell. | 09-30-2010 |
Hitesh K. Patel, Gujarat IN
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20090081801 | Process for synthesis of pyrrole derivative, an intermediate for atorvastatin - The present invention also relates to a novel impurity, (6-{2-[2-(6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxan-4-yl)-acetylamino]-ethyl}-2,2-dimethyl-[1,3]-dioxan-4-yl)-acetic acid tert-butyl ester, the compound of formula IV, having the following structure: | 03-26-2009 |
Ilesh Mahendrabhai Patel, Gujarat IN
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20110230663 | PROCESS FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE - The present invention relates to novel process for preparing Donepezil hydrochloride of formula (I) | 09-22-2011 |
Jagdish Maganlal Patel, Gujarat IN
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20160083374 | AMORPHOUS FORM OF CANAGLIFLOZIN AND PROCESS FOR PREPARING THEREOF - The present invention provides invention relates to stable amorphous form of Canagliflozin. The invention also provides the processes for the preparation of an amorphous form of Canagliflozin; and pharmaceutical compositions comprising therapeutically effective amount of an amorphous form of Canagliflozin, use of said composition for treatment of diabetes, obesity and diabetic complications, especially in type-2 diabetes. | 03-24-2016 |
Jayesh Patel, Gujarat IN
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20130150577 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES - Provided herein is a novel process for the preparation of phenylcyclopropylamine derivatives, which are useful intermediates in the preparation of triazolo[4,5-d]pyrimidine compounds. Provided particularly herein is a novel, commercially viable and industrially advantageous process for the preparation of a substantially pure ticagrelor intermediate, trans-(1R,2S)-2-(3,4-difluorophenyl)-cyclopropylamine. The intermediate is useful for preparing ticagrelor, or a pharmaceutically acceptable salt thereof, in high yield and purity. | 06-13-2013 |
Jayesh Chandubhai Patel, Gujarat IN
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20160083764 | AN IMPROVED PROCESS FOR THE PREPARATION OF FIDAXOMICIN - The present invention provides an improved process for the preparation of fidaxomicin by culturing | 03-24-2016 |
Jayesh Laljibhai Patel, Gujarat IN
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20120164188 | PALIPERIDONE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUBSTANTIALLY FREE OF IMPURITIES - Provided herein are impurities of paliperidone, 3-[2-[4-[1-(4-fluoro-2-hydroxyphenyl)methanoyl]piperidinyl-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (methanoyl impurity), 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (dehydroxy impurity) and 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-7,8-dihydro-6H-pyrido[1,2-a]pyrimidin-4,9-dione (9-keto impurity), and processes for preparing and isolating thereof. Provided further herein is a highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of methanoyl, dehydroxy and 9-keto impurities, process for the preparation thereof, and pharmaceutical compositions comprising highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of methanoyl, dehydroxy and 9-keto impurities. Provided also herein are improved and efficient processes for preparing paliperidone intermediates. | 06-28-2012 |
Jitendra Dasharathlal Patel, Gujarat IN
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20130266654 | METHOD FOR TREATMENT OF ACNE USING PHARMACEUTICAL COMPOSITIONS OF CLINDAMYCIN - The present invention relates to a method for treating, reducing or preventing acne. In particular, the present invention relates to methods for reducing the total number, incidence and severity of acne lesions on the skin which includes both inflammatory and non-inflammatory lesions. Further, the invention relates to reducing the incidence and severity of adverse events resulting from topical application of anti-acne agents resulting in improvement of skin tone. The method includes administering a novel and stable topical anti-acne pharmaceutical composition. | 10-10-2013 |
20130280308 | PHARMACEUTICAL COMPOSITIONS OF ANTI-ACNE AGENTS - The present invention relates to pharmaceutical compositions for treatment of acne. In particular, the present invention relates to stable pharmaceutical compositions for treatment of acne along with other pharmaceutically acceptable excipients. These compositions exhibit excellent stability, greater permeability, and enhanced therapeutic efficacy. The invention also relates to processes for the preparation of such compositions. | 10-24-2013 |
20130337016 | METHOD FOR TREATMENT OF ACNE USING PHARMACEUTICAL COMPOSITIONS OF CLINDAMYCIN AND ADAPALENE - The present invention relates to a method for treating, reducing or preventing acne. In particular, the present invention relates to methods for reducing the total number, incidence and severity of acne lesions on the skin which includes both inflammatory and non-inflammatory lesions. Further, the invention relates to reducing the incidence and severity of adverse events resulting from topical application of anti-acne agents resulting in improvement of skin tone. The method includes administering a novel and stable topical anti-acne pharmaceutical composition. | 12-19-2013 |
Jyotindra Bachubhai Patel, Gujarat IN
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20150344593 | Heterogeneous Ziegler-Natta Catalyst System And A Process For Olefin Polymerization Using The Same - The present disclosure provides a heterogeneous Ziegler-Natta catalyst system to be used in the preparation of ultra-high molecular weight polymers (UHMWP). The system includes at least one procatalyst, at least one co-catalyst, at least one hydrocarbon medium and at least one external donor, wherein the ratio of elemental magnesium to elemental titanium to halide, in the procatalyst, is 1:1.3:3.7; the ratio of elemental aluminum, present in the co-catalyst to elemental titanium, present in the procatalyst, ranges between 6:1 and 12:1; and the ratio of elemental silicon, present in the external donor to elemental titanium, present in the procatalyst, ranges between 1:10 and 10:1. The present disclosure also provides a process for preparation of UHMWPE using the heterogeneous Ziegler-Natta catalyst system of the present disclosure. | 12-03-2015 |
Kalpesh Ravajibhai Patel, Gujarat IN
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20150218166 | PROCESS FOR THE PREPARATION OF ACEBROPHYLLINE - The present invention relates to an improved process for preparing Acebrophylline comprising preparing a reaction mixture of theophylline-7-acetate and ambroxol base in a non-polar solvent; heating said reaction mixture at a suitable temperature; and isolating Acebrophylline by filtration. The yield of Acebrophylline is between 95-98% with a purity of 99%. | 08-06-2015 |
Ketan R. Patel, Gujarat IN
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20100120918 | NOVEL NON-AQUEOUS TOPICAL SOLUTION OF DICLOFENAC AND PROCESS FOR PREPARING THE SAME - A non-aqueous topical solution composition of pharmaceutically acceptable salt of diclofenac is disclosed. The non-aqueous topical solution composition comprises therapeutically effective amount of pharmaceutically acceptable salt of diclofenac, solublizer, penetration enhancer and solvent, and optionally a humectant, counter irritant, additional penetration enhancer and anti-oxidants and a process for preparing the same. | 05-13-2010 |
20130096201 | Pharmaceutical Compositions Comprising Paracetamol and Process for Preparing The Same - Disclosed herein are injectable compositions containing high concentration of paracetamol or its pharmaceutically acceptable salts wherein the concentration of paracetamol or its pharmaceutically acceptable salt is >150 mg/ml in a judiciously tailored solvent system comprising glycofurol, ethanol, water or a solvent system comprising glycofurol, ethanol, polyethylene glycol, water. The viscosity of the said injectables is <28 cps. Further disclosed is the process for preparing the said injectables. The injectables can be administered by intramuscular route, intravenous route or as intravenous infusion after diluting in one of the routinely used intravenous fluids, infusion solutions of antibacterial, antifungal and amoebicidal drugs and along with anxiolytics (Midazolam injection) or narcotic analgesics (Fentanyl Citrate injection etc) as they remain stable, clear and transparent at least for 6 hours after dilution. | 04-18-2013 |
20130197092 | Novel Non-Aqueous Topical Solution of Diclofenac and Process for Preparing the Same - A novel non-aqueous topical solution composition of pharmaceutically acceptable salt of diclofenac is disclosed. The non-aqueous topical solution composition comprises therapeutically effective amount of pharmaceutically acceptable salt of diclofenac, solublizer, penetration enhancer and solvent, and optionally a humectant, counter irritant, additional penetration enhancer and anti-oxidants and a process for preparing the same. | 08-01-2013 |
Ketan Rajnibhai Patel, Gujarat IN
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20130137769 | Injectable Preparations Of Diclofenac And Its Pharmaceutically Acceptable Salts - Injectable formulations of water-soluble salts of diclofenac, which cause significantly less pain at the site of injection and can be administered by intradeltoid route, in addition to intragluteal and slow intravenous route. | 05-30-2013 |
Killol Patel, Gujarat IN
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20090062549 | PROCESS FOR THE PREPARATION OF PRAMIPEXOLE AND NEW ANHYDROUS FORMS OF ITS DIHYDROCHLORIDE - The present invention provides processes for the preparation of (−) pramipexole or an acid addition salt thereof of Formula I. The present invention further provides for the novel polymorphic Forms A and B of anhydrous pramipexole dihydrochloride. | 03-05-2009 |
20100228030 | PROCESS FOR THE PREPARATION OF INTERMEDIATES OF TETRACYCLIC COMPOUNDS - The present invention relates to a process for the preparation of cis-intermediates of Formula II, (Formula II) wherein R1 represents hydrogen, (un)substituted alkyl, alkenyl, aryl, and X represents a leaving group, which are useful synthetic intermediates in the preparation of tetracyclic compounds having phosphodiesterase inhibitory activity. | 09-09-2010 |
Krishnakumar Vinubhai Patel, Gujarat IN
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20150037405 | PHARMACEUTICAL COMPOSITIONS OF LEVODOPA AND CARBIDOPA - The present invention relates to pharmaceutical compositions of levodopa and carbidopa. In particular, the invention relates to modified release pharmaceutical compositions of levodopa and carbidopa with at least one organic acidic excipient. The invention also relates to processes for the preparation of such compositions and use thereof for treatment of Parkinson's disease. | 02-05-2015 |
Manish Popatial Patel, Gujarat IN
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20090182148 | PROCESS FOR THE MANUFACTURE OF MONTELUKAST SODIUM - An improved process for the manufacture of 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid, sodium salt [montelukast sodium(I)]. It consists of converting a vital intermediate 1-(mercaptomethyl)-cyclopropane acetic acid of formula IX, to a quaternary ammonium salt of formula X, using a suitable base in a suitable solvent at 0° C. to 50° C. followed by monometalation to provide an intermediate of formula XI and subsequent condensation of XI with 2-[2-[3-(S)-[3-[2-(7-chloro-2-quinolinyl)-ethenyl]phenyl]-3-methanesulphonyloxypropyl]phenyl]-2-propanol at 0 to −50° C. to afford 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid as the quaternary ammonium salt which is filtered, purified by crystallization from a suitable solvent and finally treated with a sodium base in a suitable solvent to generate montelukast sodium which is isolated by trituration with an antisolvent. The invention provides a convenient process for preparing montelukast sodium (I) in good yields and purities. | 07-16-2009 |
Milan R. Patel, Gujarat IN
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20130096201 | Pharmaceutical Compositions Comprising Paracetamol and Process for Preparing The Same - Disclosed herein are injectable compositions containing high concentration of paracetamol or its pharmaceutically acceptable salts wherein the concentration of paracetamol or its pharmaceutically acceptable salt is >150 mg/ml in a judiciously tailored solvent system comprising glycofurol, ethanol, water or a solvent system comprising glycofurol, ethanol, polyethylene glycol, water. The viscosity of the said injectables is <28 cps. Further disclosed is the process for preparing the said injectables. The injectables can be administered by intramuscular route, intravenous route or as intravenous infusion after diluting in one of the routinely used intravenous fluids, infusion solutions of antibacterial, antifungal and amoebicidal drugs and along with anxiolytics (Midazolam injection) or narcotic analgesics (Fentanyl Citrate injection etc) as they remain stable, clear and transparent at least for 6 hours after dilution. | 04-18-2013 |
Milan Rajnibhai Patel, Gujarat IN
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20130137769 | Injectable Preparations Of Diclofenac And Its Pharmaceutically Acceptable Salts - Injectable formulations of water-soluble salts of diclofenac, which cause significantly less pain at the site of injection and can be administered by intradeltoid route, in addition to intragluteal and slow intravenous route. | 05-30-2013 |
Mitesh Jagdishkumar Patel, Gujarat IN
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20160083764 | AN IMPROVED PROCESS FOR THE PREPARATION OF FIDAXOMICIN - The present invention provides an improved process for the preparation of fidaxomicin by culturing | 03-24-2016 |
Naman Patel, Gujarat IN
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20110086619 | Methods and Systems for Automatically Registering a Mobile Phone Device with One or More Media Content Access Devices - An exemplary method includes a media content access device detecting a request provided by a mobile phone device to register the mobile phone device with the media content access device, registering the mobile phone device with the media content access device in response to the detected request, and automatically registering the mobile phone device with one or more additional media content access devices within the local area network. Corresponding methods and systems are also described. | 04-14-2011 |
20120011553 | METHOD AND APPARATUS FOR SUPPORTING SERVICES VIA A SET-TOP BOX - An approach is provided for supporting messaging services via a set-top box. A set-top box establishes communications with a user device. The set-top box receives a message from the user device, and stores the message for inclusion in a messaging log. The set-top box presents content of the messaging log via a display coupled to the set-top box. According to one embodiment, the set-top box receives network address information of the user device, maps the network address information to location information, and retrieves information from a data repository based on the location information. In another embodiment, the user device acquires information about a program being experience by a user via the set-top box, and generates a message to provide presence status information to a social network service based on the program information. | 01-12-2012 |
20120036543 | METHOD AND APPARATUS FOR CONTROLLING A SET-TOP BOX BASED ON DEVICE EVENTS - An approach is provided for controlling a set-top box based on a device event. A set-top box detects a wireless device. A communication channel is established with the wireless device configured to initiate a voice call. A command message is received, by the set-top box, over the communication channel. The command corresponds to a device event experienced by the wireless device. | 02-09-2012 |
20120036549 | METHOD AND APPARATUS FOR INTERACTING WITH A SET-TOP BOX BASED ON SENSOR EVENTS FROM A USER DEVICE - An approach is provided for controlling a set-top box based on sensor triggered events on a user device. A set-top box receives a control message from a user device, wherein the control message specifies an event corresponding to one or more sensors of the user device. The set-top box maps the event to an activity associated with an application that is executed by the set-top box. Also, the set-top box presents media content provided by the application according to the mapped activity. | 02-09-2012 |
20120162537 | METHOD AND APPARATUS FOR CONTROLLING A SET TOP BOX OVER A WIRELESS ADHOC CONNECTION - An approach is provided for controlling a set top box on an ad hoc basis. A wireless device detects a mobile terminal that is configured to control one or more set top boxes via a wireless local area network. The wireless device controls, over an adhoc connection, the one or more set top boxes directly or via the mobile terminal based on the detection of the mobile terminal. | 06-28-2012 |
20120166655 | METHOD AND APPARATUS FOR INVOKING NATIVE FUNCTIONS OF A MOBILE DEVICE TO CONTROL A SET-TOP BOX - An approach is provided for controlling a user device native function via a web-based application at a user device (e.g., a mobile terminal). The mobile terminal executes a web-based application and a shell application, wherein the shell application provides communication between the web-based application and a native function of the mobile terminal. The mobile terminal registers the web-based application with the shell application for the communication. The mobile terminal invokes the native function of the mobile terminal via the communication based upon a communication protocol that specifies a command of a native function associated with a set top box. | 06-28-2012 |
20120236788 | METHOD AND SYSTEM FOR ACCESSING STORAGE DEVICES - An approach for enabling wireless communication devices to mount and/or unmount one or more storage devices to facilitate data sharing is described. A processor of a user device generates a request message according to a storage access protocol that is operating system agnostic. The processor then initiates transmission of the request message over a wireless link of an ad-hoc network to a system that includes one or more storage devices, wherein the request message requests storage device information relating to the one or more storage devices. | 09-20-2012 |
Nileshkumar S. Patel, Gujarat IN
Pankaj R. Patel, Gujarat IN
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20090305354 | PROCESS FOR PREPARING HUMAN G-CSF - The present invention discloses an improved process for the production of G-CSF in high yield via a high salt-induced increase in plasmid stability during the production phase. | 12-10-2009 |
20100048550 | SELECTIVE TR-BETA 1 AGONIST - The present invention relates to novel compounds of general formula (I) which are thyroid receptor ligands and are preferably selective for the thyroid hormone receptor beta(TR-Beta). Further, the present invention relates to processes of preparing such compounds, their tautomeric forms, novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, methods for using such compounds and pharmaceutical compositions containing them. | 02-25-2010 |
20120142891 | FUSION PROTEIN SYSTEMS SUITABLE FOR HIGH EXPRESSION OF PEPTIDES - The present invention discloses an improved process for the production of desired recombinant peptides from bacterial cells by using G-CSF as a novel fusion partner for their high level expression in these cells. The invention further provides an expression system comprising the fusion protein wherein the G-CSF is operatively linked to the peptide of interest via an enzymatic or chemical cleavage site which can be used to separate the fusion partner from the said peptide. | 06-07-2012 |
20120264685 | SHORT CHAIN PEPTIDOMIMETICS BASED ORALLY ACTIVE GLP 1 AGONIST AND GLUCAGON RECEPTOR ANTAGONIST - The present invention provides novel short chain peptidomimetics, which act as GLP-1 receptors agonist and glucagon receptor antagonist. These dual acting peptidomimetics exhibit increased stability to proteolytic cleavage, especially against DPP-IV (Dipeptidyl peptidase-IV) enzyme, GIT enzymes such as pepsin and acidic stomach pH and also against liver microsomes (in vitro). Due to increased metabolic stability, other than parenteral route of administration, these short chain peptidomimetics can be delivered by oral routes of administration, for the treatment or prevention of diabetes and related metabolic disorders, such as obesity, hyperlipidemia and eating disorders. | 10-18-2012 |
Piyush Ambalal Patel, Gujarat IN
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20140288064 | Nitrogen containing heterocyclic compounds - Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed. | 09-25-2014 |
Pradeepkumar Patel, Gujarat IN
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20150071862 | FUNCTIONALIZED FLUORINE CONTAINING PHTHALOCYANINE MOLECULES - Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell. | 03-12-2015 |
Pradip Maganlal Patel, Gujarat IN
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20100189746 | ADAPTATION OF PITMAN MOORE STRAIN OF RABIES VIRUS TO PRIMARY CHICK EMBRYO FIBROBLAST CELL CULTURES - The present invention relates to a process of adaptation of Pitman Moore strain of rabies virus to Primary chick fibroblast cells for the production of rabies vaccine. | 07-29-2010 |
Pranav Dushyant Patel, Gujarat IN
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20110021634 | PROCESSES FOR PREPARING METFORMIN HYDROCHLORIDE - A process for reducing dimethylamine content in metformin hydrochloride is disclosed. The process comprises: | 01-27-2011 |
Shailesh Rajnikant Patel, Gujarat IN
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20100017008 | SYSTEMS AND METHODS FOR OFFLINE AND/OR ONLINE BATCH MONITORING USING DECOMPOSITION AND SIGNAL APPROXIMATION APPROACHES | 01-21-2010 |
20100063611 | SYSTEMS AND METHODS FOR REAL TIME CLASSIFICATION AND PERFORMANCE MONITORING OF BATCH PROCESSES - Systems and methods ( | 03-11-2010 |
Sobal Patel, Gujarat IN
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20130222966 | DIP SWITCH CHANGE DETECTION IN A SELF POWERED RELAY - An interface is disclosed for a self powered protection relay that uses mechanical switches for its configuration. The protection relay can include a base relay for measurement of line current and for generation of a trip signal, and a Human Machine Interface (HMI) unit for specifying, by a user, a base setting of an operating parameter of the protection relay. The base relay can be self-powered from the line and the HMI unit can include an auxiliary power supply. The protection relay is configured with mechanical switches provided in the protection relay. The HMI unit in the protection relay is designed to detect and alert the user of the relay of any change in the base setting carried out with one or more mechanical switches provided in the relay in powered and unpowered conditions of the base relay. | 08-29-2013 |
Vimalkumar Mahendrabhai Patel, Gujarat IN
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20150353656 | CATALYST COMPOSITION FOR POLYMERIZATION OF OLEFINS - A catalyst composition comprising a monoester, the compound represented by formula (I) as an internal electron donor, and optionally an additional internal electron donor selected from a group consisting of diesters and diethers, | 12-10-2015 |
20150368381 | PROCESS FOR PREPARING A CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS - A process for preparing a catalyst component, including: | 12-24-2015 |
Viralkumar Patel, Gujarat IN
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20150344593 | Heterogeneous Ziegler-Natta Catalyst System And A Process For Olefin Polymerization Using The Same - The present disclosure provides a heterogeneous Ziegler-Natta catalyst system to be used in the preparation of ultra-high molecular weight polymers (UHMWP). The system includes at least one procatalyst, at least one co-catalyst, at least one hydrocarbon medium and at least one external donor, wherein the ratio of elemental magnesium to elemental titanium to halide, in the procatalyst, is 1:1.3:3.7; the ratio of elemental aluminum, present in the co-catalyst to elemental titanium, present in the procatalyst, ranges between 6:1 and 12:1; and the ratio of elemental silicon, present in the external donor to elemental titanium, present in the procatalyst, ranges between 1:10 and 10:1. The present disclosure also provides a process for preparation of UHMWPE using the heterogeneous Ziegler-Natta catalyst system of the present disclosure. | 12-03-2015 |
20160108146 | A NOVEL TRANSITION METAL BASED PRO-CATALYST AND A PROCESS FOR ITS PREPARATION - The present disclosure relates to a transition metal based pro-catalyst represented by Formula I: wherein, the substituents have the meaning as defined in the specification. The present disclosure also relates to a process for preparing the transition metal based pro-catalyst represented by Formula I and the catalyst composition obtained therefrom. Further, the present disclosure relates to a process for polymerizing olefins by employing the catalyst composition comprising the transition metal based pro-catalyst represented by Formula I. | 04-21-2016 |