Palma
Benito Anton Palma, Mexico MX
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20080241183 | Process For The Preparation And Use Of A Bivalent Vaccine Against Morphine-Heroine Addiction - The structural design, preparative methods and chemical composition of two structural formulations of bivalent vaccines against morphine-heroin addiction (morphine-6-hemisuccinyl-EDC-TFCS-tetanus toxoid and 3-O-carboxymethylmorphine-EDC-TFCS-tetanus toxoid), are disclosed. These vaccines are suitable for human use in which they are capable of triggering the synthesis of polyclonal antibodies against morphine opiate and its structural analogue, heroin, through the repeated in vivo administration of these formulations, in active vaccination protocols, in pre-clinical studies in rodents. The active vaccination paradigm through which these immunogens trigger a humoral immune response consolidated with a long-term immunological memory, characterized by the presence of high titers of specific antibodies against these two drugs of abuse, is also disclosed. Furthermore, the present invention reveals the efficacy of these conjugate formulations for triggering a sustained immunoprotection against morphine and heroin addiction using an intravenous self-administration paradigm of these two opiate substances in the rodent. Finally, a discussion is also made on the potential future use of these immunoconjugates in active vaccination protocols for treating both morphine and heroin addiction in the humans. | 10-02-2008 |
20110318381 | PROCESS FOR THE PREPARATION AND USE OF A BIVALENT VACCINE AGAINST MORPHINE-HEROINE ADDICTION - The structural design, preparative methods and chemical composition of two structural formulations of bivalent vaccines against morphine-heroin addiction (morphine-6-hemisuccinyl-EDC-TFCS-tetanus toxoid and 3-O-carboxymethylmorphine-EDC-TFCS-tetanus toxoid), are disclosed. These vaccines are suitable for human use in which they are capable of triggering the synthesis of polyclonal antibodies against morphine opiate and its structural analogue, heroin, through the repeated in vivo administration of these formulations, in active vaccination protocols, in pre-clinical studies in rodents. The active vaccination paradigm through which these immunogens trigger a humoral immune response consolidated with a long-term immunological memory, characterized by the presence of high titers of specific antibodies against these two drugs of abuse, is also disclosed. Furthermore, the present invention reveals the efficacy of these conjugate formulations for triggering a sustained immunoprotection against morphine and heroin addiction using an intravenous self-administration paradigm of these two opiate substances in the rodent. Finally, a discussion is also made on the potential future use of these immunoconjugates in active vaccination protocols for treating both morphine and heroin addiction in the humans. | 12-29-2011 |
20130236478 | PROCESS FOR THE PREPARATION AND USE OF A BIVALENT VACCINE AGAINST MORPHINE-HEROINE ADDICTION - Provided are bivalent immunogenic composition against morphine-heroin addiction comprising a carrier protein (“CP”) and a morphinic product, wherein the CP and the morphinic product are connected by a spacer-linker arm having a total molecular size of 16-21 Å, and methods of using the same. | 09-12-2013 |
20150064212 | PROCESS FOR THE PREPARATION AND USE OF A BIVALENT VACCINE AGAINST MORPHINE-HEROIN ADDICTION - Provided are bivalent immunogenic composition against morphine-heroin addiction comprising a carrier protein (“CP”) and a morphinic product, wherein the CP and the morphinic product are connected by a spacer-linker arm having a total molecular size of 16-21 Å, and methods of using the same. | 03-05-2015 |
Fabrizio Palma, Rome IT
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20080218280 | Differential Oscillator Device with Pulsed Power Supply, and Related Driving Method - The present invention concerns a differential oscillator device, comprising resonant electronic means, capable to provide on at least two terminals at least one oscillating signal V | 09-11-2008 |
Fabrzio Palma, Roma IT
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20100085122 | DEVICE WITH TWO DIFFERENTIAL OSCILLATORS WITH PULSED POWER SUPPLY COUPLED TO AND IN QUADRATURE-PHASE WITH EACH OTHER - The present invention concerns a device having a first and a second differential oscillators ( | 04-08-2010 |
Fedeli Palma, Senna Lodigiana IT
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20120157687 | IMPROVED PROCESS FOR THE PREPARATION OF ARYLPYRIDINYL COMPOUNDS - A process is described for the preparation of arylpyridine compounds by aryl-aryl cross-coupling reactions between a halopyridine and an arylmagnesium halide carried out in the presence of a catalytic amount of a zinc salt and a catalytic amount of palladium complex with a bidentate phosphine. The zinc salt is preferably selected from ZnCl | 06-21-2012 |
Giorgio Palma, Grenoble FR
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20150078065 | NON-VOLATILE RESISTIVE MEMORY CELL - The invention more particularly relates to a resistive memory cell comprising a first and a second metal electrodes and a solid electrolyte positioned between the first and the second metal electrodes, with the solid electrolyte comprising a commutation layer in contact with the first electrode and a dielectric layer, with said resistive memory cell being able to be electrically modified so as to switch from a first resistive state to a second resistive state (state LRS) wherein the resistance (R | 03-19-2015 |
Giovanni Palma, Le Kremlin Bicetre FR
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20090164541 | Procedure for deriving a three-dimensional digital mask starting from a series of two-dimensional masks, plus a device for doing this - A derivation procedure for a three-dimensional digital mask from a series of two-dimensional masks in a radiographic device containing a source (S) of X-rays, a means of recording and a volume of interest hat contains the object to be X-rayed located between the source (S) and the means of recording consists of an extrapolation of each mask M | 06-25-2009 |
Giovanni Palma, Rue De La Miniere FR
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20140140604 | METHOD FOR PROCESSING DUAL-ENERGY RADIOLOGICAL IMAGES - A method for processing radiological images of a region of interest in a patient, the method comprising obtaining a set of images of the region of interest comprising at least two images, acquired using a medical imaging system, each image of the set of images being acquired at one X-ray energy, determining at least one recombined image by recombining a plurality of images forming a sub-set of images of the set of images for each recombination, segmenting at least one image from among the set of images, to detect and isolate at least one zone of the region of interest, and merging with the at least one recombined image whereby the at least one zone of the region of interest derived from segmentation is merged so as to visualize the at least one zone in the recombined image. | 05-22-2014 |
Giovanni Palma, Issy Les Moulineaux FR
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20120045111 | IMAGE PROCESSING METHOD TO DETERMINE SUSPECT REGIONS IN A TISSUE MATRIX, AND USE THEREOF FOR 3D NAVIGATION THROUGH THE TISSUE MATRIX - A method to generate a final image with a medical imaging system, wherein the final image highlights suspect regions in a tissue matrix and wherein the final image is generated from a first image and from previously acquired images of the tissue matrix is provided. The method comprises: creating a 3D map of suspicion from the previously acquired medical images; generating a 2D map of suspicion by projecting all or part of the 3D map of suspicion onto a plane from a point reproducing the conditions of acquisition of the first image; and generating a final 2D image of the tissue matrix from the first image and/or from the 2D map of suspicion, wherein the final 2D image highlights suspect regions in the tissue matrix. | 02-23-2012 |
Giovanni Palma, Bicetre FR
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20090304256 | METHOD OF EXTRAPOLATING A GREY-LEVEL BIDIMENSIONAL IMAGE IN A RADIOGRAPHY DEVICE AND A RADIOGRAPHY DEVICE IMPLEMENTING SUCH A METHOD - A method of extrapolating a bidimensional grey-level image using a radiography device. | 12-10-2009 |
Giovanni John Jacques Palma, Issy-Les-Moulineaux FR
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20120106697 | METHOD FOR ESTIMATING AND CORRECTING SCATTERING IN MAMMOGRAPHY - A method for correcting at least one image of an object obtained with a mammography system is provided. The method comprises: acquiring a pre-exposure image of an object to determine the acquisition conditions for main images, the pre-exposure image comprising regions corresponding to the projection of radio-opaque elements, wherein a mask comprising radio-opaque elements is in an acquisition position; acquiring the main images resulting from the passing through the object of X-rays at higher doses than the dose used for acquisition of the pre-exposure image, wherein the mask comprising radio-opaque elements is in a retracted position; extracting regions from the pre-exposure image which correspond to the projection of radio-opaque elements; and determining the contribution of X-ray scatter at every point of the at least one image of the object, on the basis of the regions extracted from the pre-exposure image. | 05-03-2012 |
Giuseppe Palma, Calimera (le) IT
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20120223710 | Method of generating 2D or 3D maps of MRI T1 and T2 relaxation times - A method of generating 2D or 3D maps of MRI T | 09-06-2012 |
Giuseppina Palma, Giugliano In Campania IT
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20120325112 | MATERIAL IN THE FORM OF LITHIUM FLUORIDE POWDER CONTAINING COLOUR CENTRES, METHOD FOR PREPARATION AND USE THEREOF - It is describes a material in the form of lithium fluoride powder containing colour centres and the method for its preparation, by the formation of colour centres based on irradiating the powder with synchrotron radiation (light). The method involves mechanically reducing the size of the particles that form the LiF powder and the formation of colour centres therein by its exposure to synchrotron radiation. The so activated powder, which maintains the transparency characteristics of the original material if exposed to sunlight, can find wide use as an additive both in common printing inks and in pigments used in the artistic field to be used for the formation of marks on artefacts for anti-counterfeiting/identification purposes. | 12-27-2012 |
Henry A. Palma, Toronto CA
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20150198548 | MEASURING INSTRUMENT FOR DETECTION OF ELECTRICAL PROPERTIES IN A LIQUID - A measuring instrument for detection of electrical properties in a liquid includes a main body configured to hold a tester, a first pole extending from the main body, and a second pole extending from the main body that is spaced apart from the first pole. The first pole carries a positive probe for attachment to the tester, and the second pole carries a negative probe for attachment to the tester. When the probes are placed in the liquid, electrical properties in the liquid are detected by the tester. | 07-16-2015 |
Luca Palma, Zibido San Giaco IT
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20150143931 | Instatllation Assembly for a Thermometer - An installation assembly for connecting a probe element to a wall of a container, comprising: a first mounting part and a second mounting part, wherein the first mounting part serves for attaching the assembly to the container wall and has a lead-through through which the probe element is insertable. The second mounting part serves for receiving and fastening the probe element and the first and the second mounting part are flexibly connected to each other. | 05-28-2015 |
Marco Palma, Leini' (to) IT
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20080252244 | SENSORLESS SPEED DETECTION OF A PM BRUSHLESS MOTOR WITH PHASE TERMINALS SHORTED - A method of determining the speed of a spinning sensorless brushless motor driven by an inverter when the phase terminals of the motor are shorted including determining a voltage related to the voltage developed in a phase leg of the inverter; from the determined voltage, determining the direction of current and providing a first signal determining transitions between current flowing in each of two directions; and from the first signal, determining the frequency of the current and thus the motor speed. | 10-16-2008 |
20080265817 | SENSORLESS SPEED DETECTION DURING ZERO VECTOR - A speed estimation method for determining the speed of a sensorless permanent magnet brushless motor having one or more phases driven by one or more stages of an inverter, each stage including high- and low-switches connected in series across a DC Bus and having a respective common switched node, the respective switched node being coupled to a respective motor phase terminal. The method includes the steps of applying an alternating sequence of Zero Vectors to the inverter, the sequence alternating between a first Zero Vector whereby motor current does not flow in the DC Bus and a second Zero Vector wherein the high and low side switches of the inverter are alternately turned on with active vector components being injected by the inverter for each inverter stage thereby to allow motor current to flow in the DC Bus, whereby the terminals of the motor during the first and second Zero Vectors are shorted to brake the motor without substantially raising the voltage of the DC Bus during the braking time; and the speed of the motor can be determined by measuring the current in a sensor of the DC bus during the time when the second Zero Vector is applied without using a sensor in the motor. | 10-30-2008 |
20090021202 | MOTOR CONTROL CIRCUIT AND METHOD WITH MECHANICAL ANGLE RECONSTRUCTION - A method of controlling a motor connected to an unbalanced load in accordance with an embodiment of the present application includes operating the motor for a predetermined period of time with a first performance parameter held constant, monitoring a signal related to a second performance parameter, monitoring electrical rotation within the motor and providing an electrical rotation signal indicative of the electrical rotation angle, sampling the signal related to the second performance parameter at a predetermined angle of electrical rotation, arranging samples provided in the sampling step in predetermined order and generating a mechanical rotation signal representing the mechanical rotation angle of a rotor of the motor based on the arrangement of samples. The mechanical rotation signal is used to control at least one of the first and second performance parameters of the motor. | 01-22-2009 |
Marco Palma, Castagneto Po IT
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20130278181 | Reverse Rotation of a Motor Configured for Operation in a Forward Direction - There are disclosed herein various implementations of a method and a system enabling operation of a motor in reverse. Such a method includes applying a first drive signal to begin rotating the motor in a reverse direction, the first drive signal being applied for a predetermined period of time. The method also includes using a position sensor signal for the motor to control motor drive in the reverse direction when the motor reaches a predetermined reverse speed, and operating the motor in the reverse direction. | 10-24-2013 |
Mario Palma, Rio Claro Sp BR
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20130230591 | PEPTIDE FOR USE AS A MEDICAMENT, IN PARTICULAR FOR THE TREATMENT OF CANCER - The invention relates to a peptide having the sequence SEQ.1: INWLKIAKKVAGML-NH2 and one or more of the variants thereof selected from among the sequences SEQ.2 to SEQ.25, or one of the mixtures thereof. The peptides are used especially as a medicament, in particular for the treatment of cancer. The invention also relates to a pharmaceutical composition including the peptides. | 09-05-2013 |
Paulo Cesar Rodrigues Palma, Campinas BR
Pedro Nuno Leal Palma, Sao Mamede Do Coronado PT
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20120065191 | PHARMACEUTICAL COMPOUNDS - The invention relates to compounds and compositions for inhibiting the enzyme fatty acid amide hydrolase (FAAH), the use of the compounds in therapy and, in particular, for treating or preventing conditions whose development or symptoms are linked to substrates of the FAAH enzyme, and methods of treatment or prevention using the compounds and compositions. | 03-15-2012 |
Pedro Nuno Leal Palma, S. Mamede Do Coronado PT
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20100113529 | DOSAGE REGIMEN FOR COMT INHIBITORS - The invention relates to the use of an oxodiazolyl compound (I) for the preparation of a medicament for the prevention or treatment of central and peripheral nervous system associated disorders, wherein said medicament is administered according to a dosing regimen having a dosing periodicity ranging from about twice a day to about once every other day. | 05-06-2010 |
20130324578 | ADMINISTRATION REGIME FOR NITROCATECHOLS - A compound of formula (I) | 12-05-2013 |
20130331416 | DOSAGE REGIMEN FOR COMT INHIBITORS - The invention relates to the use of an oxodiazolyl compound (I) for the preparation of a medicament for the prevention or treatment of central and peripheral nervous system associated disorders, wherein said medicament is administered according to a dosing regimen having a dosing periodicity ranging from about twice a day to about once every other day. | 12-12-2013 |
20140045900 | ADMINISTRATION REGIME FOR NITROCATECHOLS - A compound of formula (I) where R | 02-13-2014 |
Pedro Nuno Leal Palma, Leca Da Palmeira PT
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20090054437 | Nitrocatechol Derivatives as Comt Inhibitors - New compounds of formula I are described. The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders. | 02-26-2009 |
20100168113 | Pharmaceutical Compounds - This invention relates to novel substituted nitrocatechol derivatives, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them. | 07-01-2010 |
20120196904 | NITROCATECHOL DERIVATIVES AS COMT INHIBITORS - New compounds of formula I are described. The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders. | 08-02-2012 |
20140024682 | PHARMACEUTICAL COMPOUNDS - This invention relates to novel substituted nitrocatechol derivatives, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them. | 01-23-2014 |
20150072977 | NITROCATECHOL DERIVATIVES AS COMT INHIBITORS - New compounds of formula I are described. The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders. | 03-12-2015 |
Philip Palma, North Ryde AU
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20150029247 | METHOD OF GENERATING PRINT DATA FOR INKJET PRINTHEAD - A method of generating print data for an inkjet printhead having a plurality of ink planes. The method includes the steps of: receiving image data for a print job in a printer controller; retrieving keep-wet pattern data for each ink plane of the printhead, the retrieved keep-wet pattern data being determined using one or more input parameters; generating first print data for each ink plane in the printer controller based on the received image data; merging the first print data with the keep-wet pattern data to provide second print data for each ink plane; and sending the second print data from the printer controller to the printhead, thereby causing the printhead to print an image together with a keep-wet pattern. The keep-wet pattern is defined by a plurality of dots printed at a frequency sufficient to maintain hydration of each nozzle in the printhead. | 01-29-2015 |
20150029248 | METHOD OF INKJET PRINTING AND MAINTAINING NOZZLE HYDRATION - A method of printing from a fixed inkjet printhead having a plurality of ink planes. The method includes the steps of: feeding a print medium past the printhead in a media feed direction, the media feed direction defining relative upstream and downstream sides of the printhead; printing an image onto the print medium, the image being defined by image data; | 01-29-2015 |
20150029264 | MULTI-COLOR PRINTER WITH INK PLUMBING FOR OPTIMIZED NOZZLE HYDRATION - A multi-color printer has an array of monochrome fixed inkjet printheads aligned in a media feed direction. The printer includes: a first printhead positioned furthest upstream relative to the media feed direction; a second printhead positioned furthest downstream relative to the media feed direction; and a third printhead positioned between the first and second printheads. Each printhead is supplied with a respective ink from a multi-color ink set, the first printhead being supplied with a lowest luminance ink of the ink set and the third printhead being supplied with a highest luminance ink of the ink set. | 01-29-2015 |
Robert Palma, Stutensee DE
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20120297882 | APPARATUS FOR PIPELINE INSPECTION - An apparatus for pipeline inspection includes a body including a longitudinal axis and a sensor unit in association with the body. The sensor unit has an array of ultrasonic sensors configured to inspect a pipe wall. The sensor unit includes a skid having an outer surface intended to run adjacent or in contact with a pipe wall. The sensor unit also includes a recess, wherein the sensors are arranged in the recess at a predetermined stand off from the outer surface of the skid. The sensor unit also includes a flushing system configured to direct pipeline fluid through the recess to flush debris from the recess when the outer surface of the skid is in contact with a pipe wall. | 11-29-2012 |
20120325004 | APPARATUS FOR PIPELINE INSPECTION AND METHOD OF PIPELINE INSPECTION - An apparatus for pipeline inspection is provided. The apparatus comprising a body comprising a longitudinal axis a sensor unit in association with the body, wherein the sensor unit comprises an array of ultrasonic sensors configured to inspect a pipe wall and a skid comprising an outer surface configured to run adjacent to, or in contact with, the pipe wall, wherein the array of ultrasonic sensors are arranged at a stand off from the outer surface of the skid, and a mechanism configured to bias the outer surface of the skid into contact with the pipe wall, and to move the sensor unit between a first radial position and a second radial position in response to changes in pipe diameter. | 12-27-2012 |
20130025370 | APPARATUS FOR PIPELINE INSPECTION AND METHOD OF PIPELINE INSPECTION - An apparatus for pipeline inspection, the apparatus having a longitudinal axis, is provided. The apparatus comprises: a plurality of ultrasonic sensor units arranged for inspection of a pipe wall, each ultrasonic sensor unit comprising an array of ultrasonic sensors, wherein the plurality of ultrasonic sensor units defines two or more groups of ultrasonic sensor units, wherein the groups of ultrasonic sensor units are axially offset from one another with respect to the longitudinal axis of the apparatus, the ultrasonic sensor units in each group being spaced circumferentially from one another, and wherein the ultrasonic sensor units are arranged out of phase, to provide inspection coverage for the circumferential spacing between the sensor units in the groups of ultrasonic sensor units so that the combined output from the groups of sensor units provides 360 degrees of inspection coverage. | 01-31-2013 |
Robert Palma, Stutensee Baden-Wurttemberg DE
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20130133429 | APPARATUS FOR PIPELINE INSPECTION - An apparatus for pipeline inspection, the apparatus comprising a body comprising a longitudinal axis, an array of ultrasonic sensors configured to inspect a pipe wall, a skid comprising an outer surface configured to run adjacent to, or in contact with, the pipe wall, wherein the array of ultrasonic sensors are arranged at a stand off from the outer surface of the skid, and a chamber comprising an ultrasonic couplant, wherein the ultrasonic couplant permits ultrasound communication between the array of ultrasonic sensors and an inner surface of the pipe wall. | 05-30-2013 |
Vincenzo Palma, Fisciano IT
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20110150726 | AUTOTHERMIC CATALYTIC REACTOR WITH FLAT TEMPERATURE PROFILE FOR THE PRODUCTION OF HYDROGEN FROM LIGHT HYDROCARBONS - The present invention relates to the make of a heterogeneous gas-solid catalytic reactor operated in autothermic conditions, characterised by a flat temperature profile. This invention concurrently uses three actions to optimise the operation of the ATR reactor both in terms of energy and of catalytic activity: the adoption of a specifically formulated catalyst so as to favour a “direct type” reaction mechanism, the use and the make of the catalyst on a structured support with a high porosity and tortuosity, and characterised by high thermal conductivity and the adoption of a radial flow geometry catalytic bed. | 06-23-2011 |
Vincenzo Palma, Sesto San Giovanni IT
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20090090153 | RETAINED MANDREL ROLLING MILL FOR SEAMLESS TUBES - A rolling mill ( | 04-09-2009 |
Vincenzo Palma, Fisciano (sa) IT
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20110123423 | PHOTOCATALYTIC FLUIDIZED BED REACTOR WITH HIGH ILLUMINATION EFFICIENCY FOR PHOTOCATALYTIC OXIDATION PROCESSES - The invention relates to the realization of synthesis of organic compounds or abatement of volatile organic compounds (VOCs) in gas-solid fluidised bed photocatalytic reactor with improved illumination efficiency. The photoreactor consists of a two-dimensional fluidized bed catalytic reactor with two walls transparent to ultraviolet radiation, by an illumination system bases on a matrix of LEDs positioned near its external walls, and heated for Joule effect inside the catalytic bed to monitor the reaction temperature. Surprisingly, through the choice of a suitable catalyst and fluidized bed photoreactor operating conditions both total and partial oxidation reactions can be achieved with high activity and selectivity. Even more surprisingly, the value of the illuminated catalyst surface area per unit irradiated volume reaches values in the order of 10 | 05-26-2011 |
Vincenzo Palma, San Giovanni IT
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20120137745 | TUBE ROLLING PLANT - The present invention relates to a system and method for rolling a seamless tube. The plant comprises a main rolling mill with adjustable rolls for mandrel-rolling a semi-finished tube. The plant also comprises a fixed-roll extracting/reducing mill positioned downstream of the main rolling mill. The extracting/reducing mill is designed to extract the semi-finished tube from the mandrel and reduce its diameter to a predetermined value close to that desired for the finished tube. Finally, the plant comprises a adjustable-roll sizing mill. The sizing mill is positioned downstream of the extracting/reducing mill. This sizing mill is designed to adjust the radial position of the rolls and define the diameter of the outgoing tube. | 06-07-2012 |
20130074563 | TUBE ROLLING PLANT - The present invention teaches rolling a seamless tube, typically with a large diameter. The system comprises a furnace for heating billets produced by continuous casting. The system comprises a piercing mill for longitudinally piercing the heated billets to obtain a pierced blank. The system comprises an expanding-elongating mill for expanding the pierced blank diameter and for elongating the pierced blank to obtain a semi-finished tube. The system comprises a continuous main rolling mill with adjustable rolls for mandrel-rolling a semi-finished tube. The system comprises a fixed-roll extracting-reducing mill positioned downstream of the main rolling mill. The extracting-reducing mill extracts the semi-finished tube from the mandrel, reducing the diameter to a predetermined value close to that desired for the finished tube. The system comprises an adjustable-roll sizing mill to adjust the radial position of the rolls and define the diameter of the outgoing tube. | 03-28-2013 |