Orsini
Barbara Orsini, Firenze IT
| Patent application number | Description | Published |
|---|---|---|
| 20120226335 | INGESTIBLE CAPSULE FOR TREATING GASTRIC INFECTIONS, IN PARTICULAR FOR TREATING H. PYLORI INFECTIONS - The light capsule object of the present invention is an ingestible device designed to illuminate the gastric cavity of the stomach for therapeutic purposes directed against Helicobacter pylori (H. pylori) bacteria. It comprises: a casing transparent to visible light, in turn containing punctiform light sources, preferably constituted by LEDs, positioned immediately under said casing and capable of emitting light at appropriate wavelength bands (preferably 405 nm and 630 nm); a battery, adapted to power the LED sources for approximately 20-30 minutes (the average transit time in the stomach); a switch which allows a delayed power on and allows the tablet to be still “off” when it is swallowed. The light emitted by the capsule strikes the H. pylori bacteria anchored on the gastric wall. The light radiation is preferentially absorbed by molecules of porphyrin produced by the bacterium which works as photosensitizing agent by inducing the formation of cytotoxic molecular species. | 09-06-2012 |
Béatrice Orsini, Marseille FR
| Patent application number | Description | Published |
|---|---|---|
| 20130105746 | INSULATION MATERIAL CONTAINING MICROFIBERS FROM STEM FIBERS OF BANANA FRUIT TREES | 05-02-2013 |
Franco Orsini, Ilbesheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20130274506 | BIOBASED CARBODIIMIDES, A PROCESS FOR PREPARATION THEREOF AND USE THEREOF - The present invention relates to novel biobased carbodiimides, a process for production thereof and use thereof. The biobased carbodiimides according to the invention comprise the reaction product of at least one carbodiimide and a carbon acid compound isolated or produced from renewable raw materials and having a functionality >1 and/or a hydroxy carboxylic ester having 2-24 carbon atoms. | 10-17-2013 |
| 20140323754 | BIOBASED CARBODIIMIDES, A PROCESS FOR PREPARATION THEREOF AND USE THEREOF - The present invention relates to novel biobased carbodiimides, a process for production thereof and use thereof. The biobased carbodiimides according to the invention comprise the reaction product of at least one carbodiimide and a carbon acid compound isolated or produced from renewable raw materials and having a functionality >1 and/or a hydroxy carboxylic ester having 2-24 carbon atoms, | 10-30-2014 |
Francois Orsini, Massy FR
| Patent application number | Description | Published |
|---|---|---|
| 20080280173 | Electricity Generation Module Including a Plurality of Electrochemical Cells - An electricity generation module including: a plurality of basic electrochemical cells; plates for supporting the basic cells, the support plates forming spacers for two consecutive basic cells; and a loading mechanism configured to maintain the relative position of the basic cells and the support plates by pressure. | 11-13-2008 |
Gaetano Orsini, Monza IT
| Patent application number | Description | Published |
|---|---|---|
| 20120141565 | GLYCEROSOMES AND USE THEREOF IN PHARMACEUTICAL AND COSMETIC PREPARATIONS FOR TOPICAL APPLICATIONS - The present invention relates to vesicles for topical delivery of drugs and cosmetics, named glyceromes and characterized by high content of glycerol. The invention further relates to pharmaceutical formulations and cosmetic products containing glycerosomes. | 06-07-2012 |
Gaetano Orsini, Varese IT
| Patent application number | Description | Published |
|---|---|---|
| 20100029555 | G-CSF SITE-SPECIFIC MONO-CONJUGATES - Novel site-specific mono-conjugates of Granulocyte Colony Stimulating Factor (G-CSF) are hereby described, with analogues and derivatives thereof, which stimulate proliferation and differentiation of progenitor cells to mature neutrophiles. These conjugates have been obtained using transglutaminase to covalently and site-specifically bind a hydrophilic, non-immunogenic polymer to a single glutamine residue of the human G-CSF native sequence and analogues thereof. These novel site-specific mono-conjugated derivatives are recommended for therapeutic use since they are stable in solution and exhibit significant biological activity in vitro and a longer bloodstream half-life, as compared to the non-conjugated protein, with a consequent prolonged pharmacological activity. | 02-04-2010 |
Gaetano Orsini, Gallarate (varese) IT
| Patent application number | Description | Published |
|---|---|---|
| 20090042277 | NUCLEIC ACIDS ENCODING RECOMBINANT SOLUBLE ENDOPROTEASES - The present invention relates to the expression and secretion in | 02-12-2009 |
Gaetano Orsini, Gallarate IT
| Patent application number | Description | Published |
|---|---|---|
| 20110281797 | SITE-SPECIFIC MONOCONJUGATED INSULINOTROPIC GLP-1 PEPTIDES - The present invention is related to glucagon-like peptide-1 (GLP-1) and analogues insulinotropic peptides, monoconjugated to biocompatible polymeric molecules by enzymatic direct and site-specific transglutamination reaction as well as their pharmaceutical formulations and delivery systems for therapeutical application in dismetabolic pathologies such as type 2 diabetes. | 11-17-2011 |
Ivan Orsini, Formigine IT
| Patent application number | Description | Published |
|---|---|---|
| 20150135649 | PACKAGING UNIT AND METHOD FOR PRODUCING SEALED PACKAGES - A packaging unit for producing sealed packages from a tube of a sheet packaging material fed along a feed path having a first axis; unit comprises: jaws movable cyclically along path between a seal position in which they grip and seal tube to form sealing bands of packages, and a rest position in which they are detached from tube; and folding flaps fitted movably to jaws; folding flaps are movable between: an open position in which they are detached from tube, and a fully closed position in which they cooperate with tube for forming folded flaps in package; jaw means are also cyclically movable in an intermediate position, which is arranged between rest position and seal position; folding flaps are movable relative to jaws means into a partly closed position, which is arranged between open position and fully closed position, when jaw means are set in intermediate position. | 05-21-2015 |
Laetitia Orsini, Compiegne FR
| Patent application number | Description | Published |
|---|---|---|
| 20110055384 | METHOD FOR CREATING CONTENT, METHOD FOR TRACKING CONTENT USE ACTIONS, AND CORRESPONDING TERMINAL AND SIGNALS - A method is provided for tracking at least one use of at least one piece of multimedia content on a terminal connected to a communication network. The piece of content is transmitted to the terminal in the form of at least one description file generated according to a predetermined description format. The method includes using the piece of content by a user of the terminal, including activation of at least one interaction element; implementing at least one instruction followed by the use associated with the activated interaction element; executing the use tracking instruction controlling storage of at least one piece of information concerning the activation of the interaction element, or use tracking information; and transmitting by the terminal the piece of use tracking information to a tracking terminal in charge of processing the use tracking information. | 03-03-2011 |
Lorenzo Maria Orsini, Thiene IT
| Patent application number | Description | Published |
|---|---|---|
| 20130313153 | PACKAGING POUCH WITH FOOD FLOW PROPERTIES - In a packaging pouch made of a flexible mono or multilayer film for packaging viscous jelly and/or gravy matrix food, in which a thermo cycle such as retort, pasteurisation, hot filling or aseptic conditions are applicable, the surface of a layer of the film forming the pouch inner walls or a surface coating on the film being in contact with food comprises a substance having the effect that the surface tension of the layer or the surface coating on the layer is 24 mN/m or less and the pouch inner walls being in contact with food exhibit easy flow properties. | 11-28-2013 |
Lorenzo Maria Orsini, Massa IT
| Patent application number | Description | Published |
|---|---|---|
| 20090221752 | FOULING RELEASE COMPOSITION - The present invention relates to a fouling release composition comprising a cured or crosslinked polysiloxane and a fluorinated polymer or oligomer. The present invention also relates to the use of the said fouling release composition in fouling release coatings for application to articles submerged in seawater. | 09-03-2009 |
| 20150027618 | METHOD FOR MONITORING THE QUALITY OF AN ADHESIVE APPLICATION DURING A LAMINATION PROCESS - A method for monitoring the quality of an adhesive application during a lamination process for manufacturing a packaging laminate includes conveying a first film or foil web in a longitudinal direction, applying an adhesive material over the whole surface or in a pattern onto the moving first film or foil web and applying a second film or foil web onto the adhesive coated first film or foil web and conveying the first and second film or foil web having the intermediate deposited adhesive material layer in the longitudinal direction to a pressing station to form a laminate. A fluorescent agent may be added to and intermixed with the adhesive material such that the fluorescent agent is uniformly distributed. Fluorescence radiation emitted by an ultraviolet-exposed adhesive material layer is detected by a visual inspection system. | 01-29-2015 |
Paolo Orsini, Legnano (milan) IT
| Patent application number | Description | Published |
|---|---|---|
| 20130012507 | SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS - Compounds represented by formula (Ia) or (Ib) and wherein R and R | 01-10-2013 |
| 20130017170 | SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS - Compounds represented by formula (Ia) or (Ib) and wherein R and R | 01-17-2013 |
| 20130344031 | SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS - Compounds represented by formula (Ia) or (Ib) and wherein R and R | 12-26-2013 |
Paolo Orsini, Legnano (mi) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110281843 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS - Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. | 11-17-2011 |
| 20120157454 | ISOQUINOLIN-1 (2H) -ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 06-21-2012 |
| 20120245143 | 3-0X0-2,3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDES WITH SELECTIVE PARP-1 INHIBITION - There are provided substituted 3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide derivatives (I) which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. | 09-27-2012 |
| 20130018036 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS - Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. | 01-17-2013 |
| 20140045846 | ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 02-13-2014 |
| 20150051154 | ALKYLATING AGENTS - The present invention relates to a novel class of alkylating agents comprising a thieno-indole moiety linked to a DNA-binding moiety, which have cytotoxic activity and are useful in treating diseases such as cancer, cellular proliferation disorders and viral infections. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising them and methods of treating diseases utilizing such compounds or the pharmaceutical composition containing them. The invention also relates to the use of this novel class of alkylating agents in the preparation of conjugates. | 02-19-2015 |
| 20150051222 | PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2- -(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMIDE - The present invention relates to a process for the preparation of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide. Novel solid forms of this compound, their utility in treating diseases caused by deregulated protein kinase activity and pharmaceutical compositions containing them are also object of the present invention. | 02-19-2015 |
| 20150057292 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS - Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. | 02-26-2015 |
| 20150080316 | FUNCTIONALIZED THIENO-INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER - The invention relates to new functionalized thieno-indole derivatives of formula (I) or (II) which have cytotoxic activity and are useful in treating diseases such as cancer and cellular proliferation disorders. The invention also relates to the use of these functionalized thieno-indole derivatives in the preparation of conjugates. Formula (I) or (II) wherein R | 03-19-2015 |
Paolo Orsini, Legnano IT
| Patent application number | Description | Published |
|---|---|---|
| 20090082346 | Substituted Pyrrolo-Pyrazole Derivatives as Kinase Inhibitors - Compounds represented by formula (Ia) or (Ib) and wherein R and R | 03-26-2009 |
| 20100292207 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS - Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. | 11-18-2010 |
| 20150057291 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS - Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. | 02-26-2015 |
| 20150065520 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS - Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. | 03-05-2015 |