Orlando, US
Amy Orlando, Bloomfield Hills, MI US
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20140116086 | FRIENDSHIP BRACELET - Friendship bracelets ( | 05-01-2014 |
Bryan Orlando, Sterling Heights, MI US
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20120175935 | LEATHER TRIM COVER ASSEMBLY WITH STRETCH REDUCTION - The present invention relates a vehicle seat assembly comprising a frame, a cushion supported on the frame, and a trim cover assembly secured over the cushion, the trim cover assembly comprising a leather trim material and a reinforcing layer secured to the leather trim material, the reinforcing layer being less flexible than the leather trim material, the trim cover assembly having a percent reduction in stretch relative to a similar trim cover assembly not having the reinforcing layer of 40% to 95% as measured according to SAE J855. | 07-12-2012 |
Bryan L. Orlando, Sterling Heights, MI US
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20100296302 | INTERIOR COMPONENTS HAVING ILLUMINATION FEATURES - An interior component having an illuminated portion comprises a trim cover positioned over a substrate. At least one light conductive element is in communication with an illumination source. A carrier engages the trim cover. The carrier further secures the light conductive element to the trim cover. The carrier has a plurality of windows formed therethrough such that the light conductive element is visible through the plurality of windows. The illuminated portion may further include an emblem in communication with the light source. The illuminated interior component may be formed by a method that includes the steps of forming a light conductive element that includes extruding an optical guide and a carrier having a mounting tab thereon. | 11-25-2010 |
20130200664 | VEHICLE SEAT SIDE AIR BAG ASSEMLBY HAVING STRAP SECURED AIR BAG CHUTE - A vehicle seat air bag assembly ( | 08-08-2013 |
Daniel D. Orlando, Tempe, AZ US
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20110099069 | System and Method of Presenting a Commercial Product by Inserting Digital Content Into a Video Stream - In a commerce system, a commercial product is presented by transmitting a video stream through a communication link to present as an image on a video display. The image including a representation of the commercial product. An interactive device is used by a consumer to select a portion of the image on the video display representing the commercial product. The information related to the commercial product, such as product description, price, and ordering, is retrieved from a database or electronic search based on the selected portion of the image on the video display. Digital content containing the information related to the commercial product is generated by an adverting agent, manufacturer, or retailer. The digital content is inserted into the video stream to form composite video. The composite video is displayed on the video display to assist the consumer in completing a transaction to acquire the commercial product. | 04-28-2011 |
Dario Orlando, Parkland, FL US
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20080303196 | UPPER STRUT MOUNT ASSEMBLY - An upper strut mount assembly includes a cylindrical member. The cylindrical member includes a top portion, a bottom portion, and an annular portion. A bottom surface of the annular portion abuts at least a top portion of a rolling member thereby allowing the spring seat to rotate relative to at least the cylindrical member. A first resilient member includes a first annular portion and a second annular portion. A bottom surface of the first annular portion abuts a top surface of the cylindrical member annular portion. A second resilient member includes a first annular portion and a second annular portion. A bottom surface of the first annular potion abuts a top surface of the cylindrical member annular portion. An exposed surface of the second annular portion of the second resilient abuts an exposed surface of the second annular portion of the first resilient member. | 12-11-2008 |
David Orlando, Somerville, MA US
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20140296218 | SUPER-ENHANCERS AND METHODS OF USE THEREOF - The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer). | 10-02-2014 |
20150111761 | SUPER-ENHANCERS AND METHODS OF USE THEREOF - The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer). | 04-23-2015 |
David A. Orlando, Durham, NC US
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20120284880 | REGULATORY POLYNUCLEOTIDES AND USES THEREOF - The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided. | 11-08-2012 |
David A. Orlando, Somerville, MA US
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20140331358 | REGULATORY POLYNUCLEOTIDES AND USES THEREOF - The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided. | 11-06-2014 |
20150033407 | REGULATORY POLYNUCLEOTIDES AND USES THEREOF - The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants. Methods for expressing polynucleotides in a plant cell, plant tissue, or plants using the regulatory polynucleotide molecules disclosed herein are also provided. | 01-29-2015 |
20160032387 | METHODS AND SYSTEMS FOR EVALUATING GENES - Aspects and embodiments disclosed herein are directed to providing methods and systems for evaluating target genes and/or associated super enhancers and or super-enhance components. In some embodiments, the method includes selecting a gene associated with a super-enhancer, to provide a selected gene, evaluating the selected gene for contribution to a cell state, e.g., a state characterized by a disease or disorder (a disease/disorder state), and responsive to the evaluation, classifying the selected gene and/or associated super-enhancer. | 02-04-2016 |
Dominic Orlando, Waddell, AZ US
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20120310120 | SELF-HEATING MASSAGE STONE - A heated massage stone has a first receptacle having a first interior recess and a second receptacle having a second interior recess. A heating element is positioned in one of the first interior recess or the second interior recess. An attachment device is sued to secure the first receptacle to the second receptacle. | 12-06-2012 |
20140207028 | SELF-HEATING MASSAGE STONE - A pocket-size self-heating massage stone includes a first receptacle having a rim portion, an interior recess and being made of ceramic slip, porcelain or stoneware slip and a second receptacle having a rim portion, an interior recess and being made of ceramic slip, porcelain or stoneware slip. A heating element is arranged in the interior recess of the second receptacle and being positioned in direct contact to transmit heat directly to a surface of the second receptacle such that the heating element only directly heats the second receptacle and does not directly heat the first receptacle. A rechargeable battery is disposed within the massage stone. The first and second receptacles are connected to one another via only the rim portions and the interior recesses of the first and second receptacles are free of connectors which connect together the first and second receptacles. | 07-24-2014 |
Geraldine S. Orlando, Efland, NC US
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20120094318 | E-CADHERIN AS A BIOMARKER OF GASTROESOPHAGEAL REFLUX DISEASE - The present invention provides methods of diagnosing and identifying subjects as having GERD comprising detecting E-cadherin fragments in a biological sample from the subject. The invention further provides methods for identifying subjects as having heartburn that is responsive to proton pump inhibitor therapy and subjects having an increased likelihood of a rapid relapse of GERD after reducing the dosage of PPIs or terminating PPI therapy. In addition, the present invention provides methods for monitoring the healing of erosive and nonerosive esophagitis of GERD without the need for esophagogastroduodenoscopy or esophagogastroduodenoscopy and biopsy, respectively. | 04-19-2012 |
Gerardo Orlando, Palm Harbor, FL US
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20140148313 | Hand Guard for Striking Targets - Devices which facilitate safe martial arts target striking are disclosed. In an aspect, a hand guard device comprising a blocking surface, a grip, and a stabilizer is disclosed. The hand guard device may assist a holder in holding a striking target, such as a board, while protecting a holder hand from wild blows from an individual attempting to strike the striking target. The hand guard device provides a rigid protective barrier for all portions of the holder hand which would normally be exposed, including the thumb. | 05-29-2014 |
Gerardo Orlando, Newton, MA US
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20100215174 | RELIABLE ELLIPTIC CURVE CRYPTOGRAPHY COMPUTATION - A method for reliable computation of point additions and point multiplications in an elliptic curve cryptography (ECC) system. Two asymmetric operations are performed: one of the operations is of slightly higher complexity than a conventional ECC operation, and the other operation is of much lower complexity than the first operation. The complexity of the second operation is a function of the desired degree of reliability, or the desired probability of failure detection. The method validates a computation involving one or more points on a specified elliptic curve by selecting a second elliptic curve, deriving a third elliptic curve from the specified and selected curves, projecting points onto the derived curve, performing a computation on the derived curve involving the projected points, validating the computation on the selected curve, extracting from the computation on the derived curve a predicted result of the computation on the selected curve, and comparing the predicted result to the computation on the selected curve. A predicted result of the computation to be validated may then be extracted from the computation on the derived curve. The predicted result is compared to an actual result of a computation on the selected curve, and if the results match, the predicted result of the computation performed on the selected curve is validated. | 08-26-2010 |
20110103578 | SYSTEMS AND METHODS FOR EFFICIENTLY CREATING DIGESTS OF DIGITAL DATA - Systems and methods efficiently process digests, hashes or other results by performing multiplicative functions in parallel with each other. In various embodiments, successive processing stages are provided, with each stage performing parallel multiplicative functions and also combining input terms to reduce the total number of terms that remain to be processed. By progressively combining the active terms into a smaller number of terms for subsequent processing, the time needed to process a result can be significantly reduced. | 05-05-2011 |
20110213984 | SERIAL ARCHITECTURE FOR HIGH ASSURANCE PROCESSING - A processing system ( | 09-01-2011 |
Giuseppe Orlando, Winston-Salem, NC US
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20150238656 | ORGAN/TISSUE DECELLULARIZATION, FRAMEWORK MAINTENANCE AND RECELLULARIZATION - Methods for decellularizing organs and tissues in vitro and in vivo are provided, as are methods of maintaining organ and tissue frameworks and methods of recellularizing organs and tissues, thereby providing an approach to needed organs or tissues. | 08-27-2015 |
Jason J. Orlando, West Palm Beach, FL US
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20090296527 | SYSTEM FOR MEASURING ACOUSTIC SIGNATURE OF AN OBJECT IN WATER - A system for measuring acoustic signature of a target object in water includes a plurality of rigid segments connected to each other to form a longitudinal member and a plurality of floats connected to the longitudinal member. Two buoys are connected at two ends of the longitudinal member and two weights are suspended from the buoys, thus making the longitudinal member neutrally buoyant when suspended in water. A plurality of hydrophones and an acoustic projector of a known source level are connected to the longitudinal member. The system further includes a data acquisition system for receiving signals from hydrophones and a signal processing means for processing signals received by data acquisition and determining acoustic signature of the target object. A depth/pressure sensor may be included. A pinger is located on the target object to measure range of target object to hydrophones. Range to target object is displayed in real time. | 12-03-2009 |
Jason John Orlando, Riviera Beach, FL US
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20100285673 | BARREL NUT CONNECTOR ASSEMBLY - A connector assembly comprises a connector having a connector threaded section with threads along a length of an external surface of the connector threaded section; and a barrel nut. The barrel nut comprises a nut threaded section having threads along an internal surface of the nut threaded section, wherein the nut threaded section is barrel shaped having a length and a diameter; a fastening section coupled to the nut threaded section, the fastening section having a length and a non-circular shape comprising a plurality of sides; and a nut circular opening extending through the entire length of the fastening section and the entire length of the nut threaded section; wherein the diameter of the nut threaded section is larger than a diameter of the connector threaded section and smaller than a diameter of an opening in a barrier through which the nut is coupled to the connector. | 11-11-2010 |
Joe Orlando, Waltham, MA US
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20130046056 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 02-21-2013 |
20140296434 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 10-02-2014 |
20150080558 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 03-19-2015 |
20150252085 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 09-10-2015 |
Kenneth P. Orlando, Sterling Heights, MI US
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20130201817 | FAULT DETECTION AND MITIGATION FOR IN-VEHICLE LAN NETWORK MANAGEMENT - A method of detecting and mitigating an unintended active state of an in-vehicle communication network. The in-vehicle communication network includes a plurality of electronic control units (ECUs) communicating over a controller area network bus system. Each ECU includes both transmitting and receiving capabilities, and is configured with a communication protocol that provides guidelines for exchanging messages with other ECUs within the communication system. Each ECU enters a communication kernel active state for communicating on the bus. Virtual networks within the communication system are identified. Each virtual network includes a collection of signals involving respective ECUs whose transmission and reception are started and stopped collectively as a unit. Each respective virtual network that is active by fault is detected. Each faulty active virtual network is deactivated. | 08-08-2013 |
Kim Orlando, Tulsa, OK US
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20120189388 | FOAMED BITUMINOUS EMULSION - The invention is a foamed bituminous emulsion comprising a bituminous emulsion and vapor entrained within the bituminous emulsion, such that the foamed bituminous emulsion is a frothy mass of foam. The temperature of the foamed bituminous emulsion may be less than 100° C., less than 75° C., or less than 50° C. The vapor entrained within the bituminous emulsion may have a volume greater than 5%, 25%, or 50% by volume of the volume of the bituminous emulsion. The foamed bituminous emulsion may be combined with paving materials to produce a foamed bituminous emulsion paving mixture. A layer may by produced by forming a bituminous emulsion; foaming the bituminous emulsion to produce a foamed bituminous emulsion, where foaming the bituminous emulsion comprises causing vapor to become entrained within the bituminous emulsion; combining the foamed bituminous emulsion with paving materials to produce a paving mixture; and applying the paving mixture to an existing surface to form a new surface. The method may further comprise compacting the new surface. The paving mixture may have a temperature less than 100° C., less than 75° C., or less than 50° C. when applied to the existing surface. | 07-26-2012 |
Mark W. Orlando, Chesterfield Township, MI US
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20150190902 | ABRASIVE ARTICLE - An abrasive article useful for finishing painted or clear coated surfaces is disclosed. The abrasive article included a structured abrasive layer disposed on a backing that is adhesively attached to nonwoven layer useful for providing conformability and attachment to a hook layer. The structured abrasive layer includes a central aperture and a plurality of surrounding apertures. | 07-09-2015 |
Paul Frank Orlando, La Habra, CA US
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20140113530 | SETUP PLATFORM APPARATUS FOR BENCH AND PEDESTAL GRINDERS - A setup platform is provided for a grinder including a cutoff wheel. The setup platform includes an upper planar surface including a first edge, which may be shaped similar to the grinder housing, the first edge including a slot therein for receiving the cutoff wheel. An anchor bar is mounted horizontally to the grinder housing, and a post extending from a lower surface of the setup platform is slidable on the anchor bar such that the setup platform is slidable relative to the anchor bar to removably mount the setup platform to the grinder such that the first edge is disposed adjacent the grinder housing and the cutoff wheel is received in the slot. | 04-24-2014 |
Paul Harvey Orlando, Katy, TX US
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20160002942 | Pump Controller - A pump controller and methods for adjusting a pump speed or pump run time based on one or more pump control data. The pump control data may include forecasted weather information and non-weather information. The pump controller can be controlled remotely. | 01-07-2016 |
Robert A. Orlando, Placitas, NM US
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20160039734 | THERAPEUTIC CURCUMIN DERIVATIVES - Curcumin analogues and methods are provided for treatment of disease. | 02-11-2016 |
Robert J. Orlando, Nesconset, NY US
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20090169042 | ELECTRONIC ANTI-SABOTAGE MICROPHONE GROMMET - A tamper detection apparatus includes a housing defining an internal cavity. A sensing device embodied as a microphone is positioned within the internal cavity of the housing, which may also be a protective grommet. A conductive element spans the internal cavity and is positioned in front of the microphone. The conductive element initiates a fault signal when a specified electrical condition is met to indicate a tampering or an attempted tampering with the microphone. | 07-02-2009 |
20100097210 | WIRELESS INTERFACE DEVICE ALLOWING A RELIABLE DIGITAL AND AUDIO COMMUNICATION TRANSFER BETWEEN A SECURITY SYSTEM, POTS AND/OR IP NETWORK MODEM DEVICE - A system, method process and apparatus is presented for interfacing digital and audio communications in a security system, comprising, a control panel having one or more first radio receiver/transceivers and one or more remote alarm sensors coupled to the control panel and the control panel receiving one or more digital reports from each one or more remote alarm sensors, a wireless interface device having one or more second radio receiver/transceivers for receiving the digital reports from the control panel unit and for establishing two-way voice communication between the control panel and the wireless interface unit, one or more telephone units coupled to the wireless interface device for communicating with the wireless interface unit and at least one POTS and/or IP network modem device coupled to the wireless interface device, an IP network, wherein, the wireless interface device includes a communication processing unit for transmitting one or more digital reports to a monitoring service via the POTS and/or IP network and for establishing two-way voice communication between the control panel and the monitoring service via a voice channel connection. | 04-22-2010 |
20120133511 | METHOD AND APPARATUS FOR DETECTING CONTROL PANEL ATTACKS IN A SECURITY SYSTEM - A method and apparatus for detecting intruders. The method includes the steps of a control panel of a security system detecting an intrusion of a secured area, the control panel entering a delay period before reporting the intrusion in order to allow entry of a disarm code through a control panel disposed on a structural surface proximate an entrance to the secured area, a sensor monitoring the control panel for movement and the control panel reporting the intrusion before expiration of the delay period upon detecting movement. | 05-31-2012 |
Ronald C. Orlando, Athens, GA US
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20100297609 | VIVO ISOTOPIC LABELING METHOD FOR QUANTITATIVE GLYCOMICS - The present invention relates to a method of isotopically labeling glycans and in facilitating high throughput quantitative/comparative analysis of glycomic compositions of biological cells. The method is applicable inter alia for identifying differentiated cells and their glycomic characteristics, differentiation conditions, disease and/or therapeutic progression, diagnosing disease states, determining drug activity, establishing manufacturing efficiencies and for determining the half-life of glycans in cells. | 11-25-2010 |
20150253332 | Isotopically Labeled Glycans and Methods for Producing the Same - The present invention relates to methods for creating isotopically-labeled glycans or glycoconjugates for use in the analysis of glycans, and compositions produced from such methods. The present invention also relates to the use of isotopically labeled glycans or glycoconjugates as standards in glycan identification and/or quantification methods. In one embodiment, the method of the present invention can be used to accurately determine the levels of glycans in a sample based upon the addition of a known quantity of a standard comprising isotopically-labeled glycans to the sample prior to analysis. In one embodiment, the present invention relates to a composition for an analytical standard comprising one or more isotopically-labeled glycans or glycoconjugates. | 09-10-2015 |
Ronald M. Orlando, Westborough, MA US
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20130177364 | RIVET SEALING WASHER - A rivet sealing washer that includes a washer body with an outer surface and an inner surface and a rivet aperture. Additionally, the rivet washer includes a membrane with at least one raised high pressure point skirt or rib and at least one recessed trough that provides a continuous seal over the outer surface of the washer body, the rivet body, and the mandrel head, and is sealably and continuously connected to the perimeter of the washer body and optionally a circumferential portion of the outer surface. | 07-11-2013 |
Roy C. Orlando, Efland, NC US
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20120094318 | E-CADHERIN AS A BIOMARKER OF GASTROESOPHAGEAL REFLUX DISEASE - The present invention provides methods of diagnosing and identifying subjects as having GERD comprising detecting E-cadherin fragments in a biological sample from the subject. The invention further provides methods for identifying subjects as having heartburn that is responsive to proton pump inhibitor therapy and subjects having an increased likelihood of a rapid relapse of GERD after reducing the dosage of PPIs or terminating PPI therapy. In addition, the present invention provides methods for monitoring the healing of erosive and nonerosive esophagitis of GERD without the need for esophagogastroduodenoscopy or esophagogastroduodenoscopy and biopsy, respectively. | 04-19-2012 |
Stephen J. Orlando, Austin, TX US
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20100210582 | METHOD AND COMPOSITION FOR TREATING PATIENTS WITH A HIGH RISK OF DEVELOPING NEURO-IMMUNE DISORDERS OR DEVELOPMENTAL DELAYS, IDENTIFIED THROUGH THE UTILIZATION OF LOW HOMOCYSTEINE OR ITS PRECURSORS/METABOLITES, AS THE PREDICTOR OF SUCH RISK - A method for predicting the likelihood of developing ASD and ASD-related diseases in a subject is disclosed. The method includes the steps of measuring the level of homocysteine, a homocysteine precursor or a homocysteine metabolite in the subject and evaluating the likelihood of developing ASD and ASD-related diseases based on the result of measurement. A subject is deemed to have a high risk of developing ASD and ASD-related diseases if the level of homocysteine, the homocysteine precursor or the homocysteine metabolite in the subject is at or below a threshold level. Also disclosed are a composition for reducing the risk of developing ASD, ASD-related diseases and adult neurological abnormalities and a method for determining a vaccination schedule in a subject. | 08-19-2010 |
Thomas M. Orlando, Atlanta, GA US
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20100090099 | Method and apparatus of uniform gas-phase molecular matrix deposition for imaging mass spectrometry - Disclosed are apparatus and methods for depositing solvent-free molecules on surfaces of samples, with particular application to imaging mass spectrometry. A vacuum chamber is configured to have controllable matrix translation apparatus for controlling the position of one or more solvent-free matrices within the chamber. Sublimation apparatus is used to sublimate molecules from the solid phase matrices. One or more samples are placed separately from the solvent-free matrices within the chamber. Condensation apparatus individually cools the samples to deposit sublimated molecules on the samples. Controllable sample translation apparatus is used to control the position of the samples within the chamber. Rotatable sample holding apparatus may be used to hold and move the samples to allow deposition of molecules on multiple samples at substantially the same time. Rotatable matrix holding apparatus may also be used to hold and move a plurality of matrices to create a homogenous mixture of molecules that are deposited onto one or more samples. As surface characterization system may be used to monitor deposition of the molecules to determine their thickness and roughness. A computer may be configured to control the matrix translation apparatus, the sublimation apparatus, the condensation apparatus, and the sample translation apparatus to provide for automated deposition of solvent-free molecules on the samples. | 04-15-2010 |
Thomas Michael Orlando, Atlanta, GA US
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20090121127 | SYSTEM AND METHOD FOR SPATIALLY-RESOLVED CHEMICAL ANALYSIS USING MICROPLASMA DESORPTION AND IONIZATION OF A SAMPLE - A method and system for desorbing and ionizing molecules from a sample for mass spectrometry using a microplasma device is disclosed. The system and method relies upon a microplasma device, or array of such devices, to partially ionize a gas to form a microplasma. The ionized gas can be a mixture of a noble gas, such as neon or argon, and hydrogen (H | 05-14-2009 |
20110318257 | PRODUCTION OF GRAPHENE SHEETS AND FEATURES VIA LASER PROCESSING OF GRAPHITE OXIDE/ GRAPHENE OXIDE - Graphene production using a continuous or pulsed laser beam focused on a substrate of graphite oxide in a significantly inert environment is disclosed. Laser-induced graphene features are characterized by a 2D-band in the Raman spectra. When the photons of the laser at a various frequencies and power levels beam impinge a graphite oxide foil for various amounts of time, a strip, divet, trench, or hole, having graphene at the bottom or sides is produced. The concentration of the graphite oxide and the laser beam may be adjusted so that the depth of the trench created is a certain depth less than the thickness of the foil. Additionally, in some embodiments, the evaporation of the water during the Hummers method is adjusted so that there remains interlaminar water in the graphite oxide foil. The presently disclosed subject matter may also be used in patterning using rastering or substrate motion. | 12-29-2011 |