Old
Christof Old, Bad Mergentheim DE
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20100003075 | SHAFT-HUB CONNECTION WITH TOOTHING - A method for producing a shaft-hub connection, in particular between a helically toothed pinion ( | 01-07-2010 |
20100104358 | Clamping Element for Connecting a Motor Shaft to a Transmission via a Hub - In the case of a clamping element for connecting a motor shaft to a transmission via a hub ( | 04-29-2010 |
Constance Old, New York, NY US
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20120183471 | SPECIFIC BINDING PROTEINS AND USES THEREOF - The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to amplified epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof. | 07-19-2012 |
20120283115 | SEROMIC ANALYSIS OF OVARIAN CANCER - The invention relates to the discovery of cancer antigens associated with ovarian cancer. In further aspects, the invention relates to methods, compositions and kits for the diagnosis and treatment of cancer, particularly ovarian and pancreatic cancers. | 11-08-2012 |
Fraser Patison Old, Milsons Point AU
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20130167415 | WINE LABEL - The present invention discloses a wine label ( | 07-04-2013 |
John A. Old, Marietta, GA US
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20150066861 | Flexible Time-based Aggregated Derivations for Advanced Analytics - Methods, system, and devices for improving pre-modeling processing of data for use in predictive modeling. A computing device may be configured to perform operations for processing client data using metadata describing various client-specific parameters. Received client data may be loaded within stage tables based on the client-specific parameters, such flat file locations. The computing device may perform various validation checks on the loaded data, such as checks to identify duplication data records associated with client data received at different times, duplication data records occurring within an overlap period, and deleted records. In an embodiment, the computing device may perform additional checks to validate data records that include changing status information, such as marital status data of an employee. The computing device may use processed client data to generate weekly aggregated tables based on custom aggregation timeframes. In an embodiment, the computing device may archive aggregated data for subsequent use. | 03-05-2015 |
Lioyd Old, New York, NY US
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20090263394 | A34 AND A33-LIKE 3 DNA PROTEIN, ANTIBODIES THERETO AND METHODS OF TREATMENT USING SAME - Polynucleotide molecules and polypeptide molecules A34 and A33-like 3 are described, as well as antibodies to polypeptide molecules A34 and A33-like 3. Also described are methods of detecting cancers expressing these polypeptides, and methods and kits for diagnosing said cancers, and methods of inhibiting effects of a cancer in a patient. | 10-22-2009 |
20110129483 | Membrane transporter NaPi2b (SCL34A1) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy - The present disclosure relates generally to the membrane transporter NaPi2b (SLC34A2) as a target for therapy, including immunotherapy, and particularly cancer therapy. The SLC34A2 epitope peptide encompassing amino acids 312-340 of SLC34A2 has been identified as an ovarian cancer epitope using the monoclonal antibody MX35. The invention also relates to the use of SLC34A2 and particularly SLC34A2 peptides in generating antibodies which have anti-tumor or anti-cancer activity or in stimulating an immunological response. The invention further relates to antibodies specifically directed against NaPi2b (SLC34A2) and the SLC34A2 peptide (s), including veneered, chimeric, single chain and humanized antibodies. Methods for generating an immune response and for treatment of tumors and cancer are also provided. Assays for screening and identifying compounds directed against SLC34A2, including the SLC34A2 epitope peptide, and additional antibodies are provided. | 06-02-2011 |
Lioyd J. Old, New York, NY US
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20110150759 | MONOCLONAL ANTIBODY 175 TAGETING THE EGF RECEPTOR AND DERIVATIVES AND USES THEREOF - The present invention relates to antibodies, particularly antibody 175, and fragments thereof or antibodies derived therefrom, which bind to the EGF receptor, particularly to amplified or overexpressed epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. These antibodies are useful in the diagnosis and treatment of cancer. Recombinant or hybrid antibodies having the variable region heavy or light chain sequence(s) of antibody 175 are also provided. The antibodies of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof. | 06-23-2011 |
Lloyd Old, New York, NY US
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20090203123 | Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per SE, and uses thereof - The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention. | 08-13-2009 |
20100278850 | Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof - The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention. | 11-04-2010 |
Lloyd Old US
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20120039892 | A34 AND A33-LIKE 3 DNA PROTEIN, ANTIBODIES THERETO AND METHODS OF TREATMENT USING SAME - Polynucleotide molecules and polypeptide molecules A34 and A33-like 3 are described, as well as antibodies to polypeptide molecules A34 and A33-like 3. Also described are methods of detecting cancers expressing these polypeptides, and methods and kits for diagnosing said cancers, and methods of inhibiting effects of a cancer in a patient. | 02-16-2012 |
Robert Old, London GB
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20130337450 | DETECTION OF QUANTITATIVE GENETIC DIFFERENCES - The present invention relates to uses and methods for the detection of a quantitative difference between first and second target sequence regions present in a nucleic acid sample, in particular but not exclusively a DNA sample, and a kit for carrying out the uses and methods of the invention. | 12-19-2013 |
Robert S. Old, Three Rivers, MI US
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20130341292 | INDUCTIVELY COUPLED PRODUCT POSITIONING SYSTEM - A product positioning apparatus for use on display shelves is provided. The system has a track with opposed sides, and a front portion that houses an inductive transmission coil. A product pusher is coupled to the track, and is guided down the track along the sides. The pusher has an inductive receiving coil in it, that provides power to a display element on the front face of the pusher, when the receiving coil is in proximity to the transmission coil within the track. The system also includes a biasing element that biases the pusher to the front of the track. A forward stop element is coupled directly in front of the track, and stops products on the track at the front of the shelf. | 12-26-2013 |
20140251933 | SHELVING ASSEMBLY - A shelving system includes a retaining wall having a panel of integrally formed flanges extending therefrom in spaced columns and rows, with each flange defining a pocket with the panel. The system includes one or more shelves, with each shelf including a support platform, opposing side panels, and a back panel extending from the support platform. A portion of the back panel forms a hook configured for engagement with one of the pockets. | 09-11-2014 |
Thomas Eugene Old, Santa Barbara, CA US
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20140051949 | SYSTEM AND METHODS FOR LOCATING RELATIVE POSITIONS OF MULTIPLE PATIENT ANTENNAS - Systems and methods described herein use near field communications to locate a set of antennas attached to, coupled with, or near the patient. A signal emitted by an antenna in the set of antennas can be received by the other antennas in the set. A second signal can be further transmitted from another antenna in the set. The differential phase and/or time shifts between the antennas from the multiple signal transmissions can contain sufficient information to find the locations of the antennas in antenna centric coordinates. The antenna locations can then be used to find a location of a pill transmitter swallowed by the patient. | 02-20-2014 |
20140058221 | SYSTEM AND METHODS FOR LOCATING A RADIOFREQUENCY TRANSCEIVER IN THE HUMAN BODY - Systems and methods described herein use near field communications to locate a radiating transponder, such as a pill swallowed by a patient. The system can be triggered to turn on and transmit an amplitude shift keyed waveform (or other type of waveform) to a set of antennas attached to, coupled with, or near the patient at roughly known locations. The magnetic field emitted by the transponder can be measured by the receiving antennas, for example, using principles of mutual inductance. The differential phase and/or time shifts between the antennas can contain sufficient information to find the location of the transponder and optionally its orientation relative to body coordinates. The system can display the location and/or orientation of the transponder and may optionally provide other information about the movement, flow, or other characteristics of pill to assist clinicians with diagnosis. | 02-27-2014 |
20140309967 | Method for Source Identification from Sparsely Sampled Signatures - The present invention relates to the method to identify the source of a signature signal by processing sparse digital data collected by a sensor system in a laboratory, field, or other application. The invention specifically addresses weak, obscured, or partially sampled signatures collected by a sensor system. The method takes advantage of all sources of data using an innovative method that uses Bayes Theorem for performing probability arithmetic and statistical inference. The method requires an exclusive and exhaustive library of candidate signatures. The method finds the most likely signature candidate from the library that has the highest likelihood of being responsible for the measured signal. In addition, the method can work with mixtures of library candidates to find the most likely mixture that explain the data. The method is applicable to a variety of sensor systems that collect and digitize data as signal strength (ordinate) versus measurement attribute (abscissa). | 10-16-2014 |
20150112189 | NEARLY ISOTROPIC DIPOLE ANTENNA SYSTEM - Systems and methods described herein can use near field communications to locate a radiating transmitter, such as a pill transmitter swallowed by a patient. In some embodiments, the pill transmitter can include multiple transmitting elements configured to transmit signals in an axis orthogonal with respect to each other. Further, in some embodiment, the pill transmitter can also include multiple transmitting elements in each of the three axes where the three axes may be perpendicular with respect to each other. The magnetic field emitted from the pill transmitter can be measured by the receiving antennas, for example, using principles of mutual inductance. | 04-23-2015 |
20150196229 | SYSTEM AND METHODS FOR TRIGGERING A RADIOFREQUENCY TRANSCEIVER IN THE HUMAN BODY - Systems and methods described herein use near field communications to locate a radiating transponder, such as a pill swallowed by a patient. The system can be triggered to turn on and transmit a waveform to a set of antennas attached to, coupled with, or near the patient. The magnetic field emitted by the transponder can be measured by the receiving antennas, for example, using principles of mutual inductance. The differential phase and/or time shifts between the antennas can contain sufficient information to find the location of the transponder and optionally its orientation relative to body coordinates. The system can display the location and/or orientation of the transponder. Further, the pill can include a reservoir to deliver a payload at a particular site of the patient's body based at least in part on the determined location. | 07-16-2015 |
William M. Old US
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20150214050 | NANOWIRE ARTICLE AND PROCESSES FOR MAKING AND USING SAME - A nanowire article includes a substrate; a plurality of nanowires disposed on the substrate, the nanowires comprising a semiconductor nitride, the semiconductor comprising an element selected from group 3 of the periodic table; and a superlattice layer interposed between the substrate and the plurality of gallium nitride nanowires. A process for producing a nanowire article includes disposing a superlattice layer on a substrate; disposing a first buffer layer on the superlattice layer; contacting the first buffer layer with a precursor; and forming a plurality of nanowires from the precursor on the first buffer layer to form the nanowire article, the nanowires comprising a semiconductor nitride, the semiconductor comprising an element selected from group 3 of the periodic table. A process for producing a nanowire article includes nitrogenating a substrate to form a nitrogenated layer on the substrate; contacting the nitrogenated layer with a precursor; and forming a plurality of gallium nitride nanowires from the precursor on the nitrogenated layer to form the nanowire article in an absence of a catalyst, wherein individual gallium nitride nanowires of the plurality of gallium nitride nanowires include a length axis that is substantially perpendicular to the nitrogenated layer. | 07-30-2015 |
William M. Old, Denver, CO US
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20150214050 | NANOWIRE ARTICLE AND PROCESSES FOR MAKING AND USING SAME - A nanowire article includes a substrate; a plurality of nanowires disposed on the substrate, the nanowires comprising a semiconductor nitride, the semiconductor comprising an element selected from group 3 of the periodic table; and a superlattice layer interposed between the substrate and the plurality of gallium nitride nanowires. A process for producing a nanowire article includes disposing a superlattice layer on a substrate; disposing a first buffer layer on the superlattice layer; contacting the first buffer layer with a precursor; and forming a plurality of nanowires from the precursor on the first buffer layer to form the nanowire article, the nanowires comprising a semiconductor nitride, the semiconductor comprising an element selected from group 3 of the periodic table. A process for producing a nanowire article includes nitrogenating a substrate to form a nitrogenated layer on the substrate; contacting the nitrogenated layer with a precursor; and forming a plurality of gallium nitride nanowires from the precursor on the nitrogenated layer to form the nanowire article in an absence of a catalyst, wherein individual gallium nitride nanowires of the plurality of gallium nitride nanowires include a length axis that is substantially perpendicular to the nitrogenated layer. | 07-30-2015 |