Patent application number | Description | Published |
20130060267 | CANNULA TIPS, TISSUE ATTACHMENT RINGS, AND METHODS OF DELIVERING AND USING THE SAME - A surgical cannula system. The surgical cannula system includes a cannula having a proximal end, a distal end, and a lumen extending therebetween. A tissue attachment ring, being configured to be coupled to a biological tissue, includes a lumen extending therethrough. A locking mechanism has a first locking state, in which the cannula is configured to move with respect to the tissue attachment ring, and a second locking state, in which movement of the cannula with respect to the tissue attachment ring is resisted. | 03-07-2013 |
20140364880 | CANNULA TIPS, TISSUE ATTACHMENT RINGS, AND METHODS OF DELIVERING AND USING THE SAME - A surgical cannula system. The surgical cannula system includes a cannula having a proximal end, a distal end, and a lumen extending therebetween. A tissue attachment ring, being configured to be coupled to a biological tissue, includes a lumen extending therethrough. A locking mechanism has a first locking state, in which the cannula is configured to move with respect to the tissue attachment ring, and a second locking state, in which movement of the cannula with respect to the tissue attachment ring is resisted. | 12-11-2014 |
Patent application number | Description | Published |
20100187283 | Method For Feeding Staples In a Low Profile Surgical Stapler - A method for feeding a fastener including the step of providing a device having a housing, at least one fastener within the housing, wherein the fastener is disposed within the housing in a first plane, an elongated actuator disposed within the housing, the actuator comprising a shaft substantially parallel to a longitudinal axis of the housing and rigidly spaced from the fastener in a second plane the actuator comprising at least one radially extending advancer disposed along a length thereof. The method further includes the step of rotating the actuator so to engage the fastener, and longitudinally moving the actuator to advance the fastener. | 07-29-2010 |
20100187284 | Apparatus For Feeding Staples In a Low Profile Surgical Stapler - A mechanism for feeding a fastener including a housing having a longitudinal axis and at least one fastener within the housing. The fastener has a crown and at least two legs extending therefrom. The fastener is disposed within the housing in a first plane parallel to the longitudinal axis. The mechanism includes an elongated actuator disposed within the housing. The actuator has a shaft substantially parallel to the longitudinal axis of the mechanism and rigidly spaced from the fastener in a second plane. The actuator has at least one radially extending advancer disposed along a length thereof, and a mechanism for rotating the actuator so that the advancer engages the fastener. | 07-29-2010 |
20110054258 | FOAM PORT INTRODUCER - The present disclosure relates to devices for introducing a port within a body cavity. The system includes a compressible port that collapses radially for positioning into an introducer that is inserted into an incision. Methods for using the devices are also described. | 03-03-2011 |
20120111919 | Surgical Stapler Fastening Device - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means. | 05-10-2012 |
20120125971 | Surgical Stapler Fastening Device - A fastener applying device including a staple housing having a proximal end attached to a handle, a distal end, and a longitudinal axis therebetween. There is at least one fastener within the housing. The device also includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device also includes an adjustment nut connecting the staple housing to the handle. Rotation of the adjustment nut changes the distance. | 05-24-2012 |
20120160890 | Surgical Fastener for Applying A Large Staple Through A Small Delivery Port - A surgical fastener applying device having a handle with a trigger pivotably attached thereto and movable within a trigger plane. The trigger has a bottom portion extending from the handle and a top portion disposed within a housing of the handle. The device has a staple housing with a proximal end attached to the handle, a distal end extending therefrom and a longitudinal axis therebetween. The housing has a firing bar disposed within, and the trigger is coupled to the firing bar. The device has a link member with a first end pivotably attached to the top portion of trigger, the link member has a second end comprising a slidable pin. The pin engages a three dimensional cam path disposed within the housing. The link member follows distal and proximal movement of the top portion of the trigger, and the pin slides perpendicular to the trigger plane to follow the three dimensional cam path. | 06-28-2012 |
20120193394 | Surgical Stapler Having an Adjustment Feature - A fastener applying device for surgically attaching tissue together. The device includes a staple housing having a proximal end attached to a handle, a distal end and a longitudinal axis therebetween. There is at least one fastener within the housing. The device includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device further includes an adjustment nut connecting the staple housing to the handle, wherein rotation of the adjustment nut changes the distance. | 08-02-2012 |
20120193399 | Surgical Fastener Having A Safety Feature - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing having a proximal position and a distal position. When the anvil is in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop, wherein at least one fasteners is placed around the anvil when the anvil is in distal position. And a distal end of the anvil extends distal to the distal end of the staple housing. The applier further includes a first means for moving the anvil distally during a deployment of the at least one fastener, and a second means for moving the anvil distally during the deployment of the at least one fastener, wherein the second means is independent of the first means. | 08-02-2012 |
20130193183 | SURGICAL STAPLER FASTENING DEVICE - A fastener applying device including a staple housing having a proximal end attached to a handle, a distal end, and a longitudinal axis therebetween. There is at least one fastener within the housing. The device also includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device also includes an adjustment nut connecting the staple housing to the handle. Rotation of the adjustment nut changes the distance. | 08-01-2013 |
20130193184 | SURGICAL STAPLER FASTENING DEVICE - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means. | 08-01-2013 |
20140151435 | Surgical Device with Tandem Fasteners - A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means. | 06-05-2014 |
Patent application number | Description | Published |
20090148453 | Monoclonal antibodies against HMGB1 - In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to a vertebrate high mobility group box (HMGB) polypeptide, methods of detecting and/or identifying an agent that binds to an HMGB polypeptide, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade and methods of detecting an HMGB polypeptide in a sample. | 06-11-2009 |
20110110936 | ANTI-GCC ANTIBODY MOLECULES AND RELATED COMPOSITIONS AND METHODS - Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The antibodies bind an extracellular domain of GCC and can be internalized. In some embodiments, the antibodies are humanized, chimeric or human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein. | 05-12-2011 |
20110217292 | MONOCLONAL ANTIBODIES AGAINST HMGB1 - In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to a vertebrate high mobility group box (HMGB) polypeptide, methods of detecting and/or identifying an agent that binds to an HMGB polypeptide, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade and methods of detecting an HMGB polypeptide in a sample. | 09-08-2011 |
20130123562 | System and Method for Disposal of Mutagen Waste - An assembly and method for processing human waste includes providing a supporting base having an opening within which a waste reservoir is affixed. The assembly may be installed on or below a rim of a toilet bowl. Solidification and pathogen killing materials are provided. The materials are deposited in the reservoir either prior to or upon accumulation of waste in the reservoir. The reservoir with the solidified waste is then sealed and transported to a collection facility. | 05-16-2013 |
20130287783 | ANTI-GCC ANTIBODY MOLECULES AND METHODS FOR USE OF SAME - Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein. | 10-31-2013 |
20140343343 | System and Method for Disposal of Mutagen Waste - An assembly and method for processing human waste includes providing a supporting base having an opening within which a waste reservoir is affixed. The assembly may be installed on or below a rim of a toilet bowl. Solidification and pathogen killing materials are provided. The materials are deposited in the reservoir either prior to or upon accumulation of waste in the reservoir. The reservoir with the solidified waste is then sealed and transported to a collection facility. | 11-20-2014 |
20150086546 | HUMANIZED ANTI-CCR2 ANTIBODIES AND METHODS OF USE THEREFOR - The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods. | 03-26-2015 |