Oana
Oana Argintaru, Philadelphia, PA US
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20160002270 | SYNTHESIS AND USE OF FLUORINATED COMPOUNDS - The invention is directed to the preparation of fluorinated compounds and their use in organic synthesis. In particular, the invention is directed to methods of reacting compounds of structure with R | 01-07-2016 |
Oana Baltaretu, Palo Alto, CA US
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20090037161 | Methods for improved simulation of integrated circuit designs - A method of improved simulator processing is provided. The method according to the current invention includes grouping frequently accessed data into one set id to improve memory hierarchy performance. The method further includes simulating predication in a non-predicated architecture to improve CPU performance. The simulated predication includes pseudo-predicated implementation of read-operation vector element access pseudo-predicated implementation of write-operation vector element access, and predicated implementation of multi-way branches with assignment statements having a same left-hand-side (lhs). The method further includes determining a selection path in a multi-sensitive “always” block to reduce taken branches. The multi-sensitive “always” block selection path determination includes generating instance-specific code to save port allocation storage, and generating inlined instance-specific code to combine sensitive actions. The method further includes regenerating code affected by the assignment statement to implement value-change callback. | 02-05-2009 |
Oana Cociorva, San Diego, CA US
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20110034436 | SPIROCYCLIC AMINOQUINOLNES AS GSK-3 INHIBITORS - Provided herein are spirocyclic aminoquinolones of formula I and compositions containing the compounds. The compounds and compositions provided herein are useful in the prevention, amelioration or treatment of GSK-3 inhibitors mediated diseases. In Formula (I): X | 02-10-2011 |
20140005184 | SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS | 01-02-2014 |
Oana Nitulescu, Ann Arbor, MI US
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20130144580 | PROCESS FOR DESIGNING AND MANUFACTURING AN IGNITION SYSTEM FOR AN INTERNAL COMBUSTION ENGINE - The present invention provides a process for designing and manufacturing an ignition system for an internal combustion engine. The process can include performing a plurality of simulations that include simulating an electrical circuit with a spark initiating device for igniting the fuel mixture within an internal combustion chamber, an electrical breakdown proximate to the spark initiating device, a plasma arc and an afterglow regime. | 06-06-2013 |
20130184974 | PROCESS FOR REDUCING ABNORMAL COMBUSTION WITHIN AN INTERNAL COMBUSTION ENGINE - The present invention provides a process for reducing abnormal combustion within a combustion chamber of the engine. The process can include simulation of the piston-driven internal combustion engine with oil droplets from the crankcase entering into the combustion chamber. In addition, the oil drops entering into the combustion chamber can be simulated as hot spots, as can simulation of fuel combustion within the combustion chamber. A probability of pre-ignition for at least a portion of the simulated hot spots as a function of the simulated fuel combustion and the simulated hot spots within the combustion chamber can be calculated and based on the calculation a combustion chamber parameter can be altered such that pre-ignition within the combustion chamber is reduced. | 07-18-2013 |
20150310138 | METHOD FOR ANALYZING OXIDATION IN AN INTERNAL COMBUSTION ENGINE - A process for analyzing incomplete fuel oxidation in an internal combustion engine is provided. The process includes simulating a cylinder with a cylinder wall and a piston within the cylinder for the internal combustion engine. Based on the simulation of the internal combustion engine operation, a pressure and a temperature are determined at a predetermined location within the cylinder for at least one piston crank angle. In addition, combustion of fuel at the predetermined location within the cylinder is simulated and a determination of combustion products is provided. In this manner, simulation of incomplete oxidants produced during operation of the internal combustion engine is afforded and can be used for the design of engine components such as cylinder walls, piston heads, piston rings, valves, spark plugs, and the like. | 10-29-2015 |
Oana Popa-Nita, Nantes FR
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20150240304 | GENES AND GENES COMBINATIONS BASED ON GENE MKNK1 PREDICTIVE OF EARLY RESPONSE OR NON RESPONSE OF SUBJECTS SUFFERING FROM INFLAMMATORY DISEASE TO CYTOKINE TARGETING DRUGS (CYTD) OR ANTI-INFLAMMATORY BIOLOGICAL DRUGS - This invention refers to the field of human medicine and specifically to the diagnosis/prognosis of the responsiveness to a cytokine targeting drug (Cy TD) or an anti-inflammatory biological drug treatment of a subject suffering from an inflammatory disease. More precisely, the present invention concerns a method for the in vitrodiagnosis/prognosis of a Cy TD or an anti-inflammatory biological drug responsive or non-responsive phenotype, comprising: (a) determining from a subject biological sample an expression profile comprising the gene MKNK1; or of the genes MKNK1 and GNLY; or of the genes MKNK1, TBX21 and TGFBR3; or of the genes MKNK1, GNLY, and ADI1; or of the genes MKNK1, GNLY, ADI1, and IL1B; or of the genes MKNK1, GNLY, ADI1, IL1B, and IL1R1; or of the genes MKNK1, PRF1, TBX21, TGFBR3, IFNGR2, FYN, IL1B and CFLAR; or of the genes MKNK1, PRF1, TBX21, TGFBR3, IFNGR2, FYN, IL1B, CFLAR, MAPK14 and GNLY; or of the genes MKNK1, PRF1, TBX21, TGFBR3, IFNGR2, FYN, IL1B, CFLAR, CD14 and TGFBR2; or of the genes MKNK1, IFNGR2, IL1B, MAPK14, GNLY, and CD14; or of the genes MKNK1, PRF1, TBX21, TGFBR3, IFNGR2, IL1B, CFLAR, MAPK14, GNLY, CD14 and TGFBR2; or of all the 46 genes of following Tables 2, 3 and 4; or Equivalent Expression Profile thereof, provided that, in said Equivalent Expression Profile thereof, MKNK1 is not replaced by gene S 100A8 nor gene MAPK14, and (ii) optionally one or more housekeeping gene(s), (b) comparing the obtained expression profile with at least one reference expression profile, and (c) determining the responsive or non-responsive phenotype from said comparison. The present invention also relates to kits and nucleic acid microarrays for performing said method. The present invention also relates to methods of treatment of inflammatory disease-suffering patients. | 08-27-2015 |
Oana Sterlacci, Las Vegas, NV US
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20130304657 | LOCATION-BASED CONNECTION SYSTEM FOR REAL ESTATE AGENTS AND CLIENTS THEREOF - A connection system configured to connect real estate agents and clients based on their relative locations allows rapid deployment of real estate services, such as property viewings. The connection system may include one or more connection servers, agent access devices, and client access devices. A set of nearby agents may be determined based on a client's location. The nearby agents that are available to provide a showing of the client's desired property may be presented to the client for selection. The system may provide identification, biographical, and professional experience information to the client to allow an informed selection. A selected agent may the confirm his or her availability and proceed to show the property to the client. | 11-14-2013 |
Oana Zaberca, Toulouse FR
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20120231276 | SOLID MATERIAL IN THE DIVIDED STATE, PROCESS FOR THE PRODUCTION OF SUCH A MATERIAL, AND USE OF SUCH A MATERIAL IN A PHOTOVOLTAIC CELL - The invention relates to a solid material with the following formula (A) : (Cu | 09-13-2012 |
20140044969 | COLLOIDAL DISPERSION OF A MATERIAL IN A DIVIDED STATE AND CONSISTING OF METAL CHALCOGENIDE IN AN AQUEOUS MEDIUM, MATERIAL IN A DIVIDED STATE, AND USES THEREOF - A colloidal dispersion of a metal chalcogenide material in divided state in an aqueous liquid phase selected from the group consisting of aqueous solutions and solutions including a mixture of water and at least one solvent that is miscible with water, wherein the carbon element of the material is present in a proportion of less than 2.5 wt. % as determined by elemental analysis, the concentration of the material in the colloidal dispersion is more than 40 g/l, and the colloidal dispersion has a charge potential value which is negative and the absolute value of which is higher than 20 mV. | 02-13-2014 |