Nussbaumer
Billy Nussbaumer, Boudry CH
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20160128789 | NOTCHED APPARATUS FOR GUIDANCE OF AN INSERTABLE INSTRUMENT ALONG AN AXIS DURING SPINAL SURGERY - Described herein is a surgical instrument guide for use with a robotic surgical system, for example, during spinal surgery. In certain embodiments, the guide is attached to or is part of an end effector of a robotic arm, and provides a rigid structure that allows for precise preparation of patient tissue (e.g., preparation of a pedicle) by drilling, tapping, or other manipulation, as well as precise placement of a screw in a drilled hole or affixation of a prosthetic or implant in a prepared patient situation. | 05-12-2016 |
Billy Nussbaumer, Preverenges CH
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20150100066 | APPARATUS, SYSTEMS, AND METHODS FOR PRECISE GUIDANCE OF SURGICAL TOOLS - Described herein are systems, apparatus, and methods for precise placement and guidance of tools during a surgical procedure, particularly a spinal surgical procedure. The system features a portable robot arm with end effector for precise positioning of a surgical tool. The system requires only minimal training by surgeons/operators, is intuitive to use, and has a small footprint with significantly reduced obstruction of the operating table. The system works with existing, standard surgical tools, does not require increased surgical time or preparatory time, and safely provides the enhanced precision achievable by robotic-assisted systems. | 04-09-2015 |
20150196365 | NOTCHED APPARATUS FOR GUIDANCE OF AN INSERTABLE INSTRUMENT ALONG AN AXIS DURING SPINAL SURGERY - Described herein is a surgical instrument guide for use with a robotic surgical system, for example, during spinal surgery. In certain embodiments, the guide is attached to or is part of an end effector of a robotic arm, and provides a rigid structure that allows for precise preparation of patient tissue (e.g., preparation of a pedicle) by drilling, tapping, or other manipulation, as well as precise placement of a screw in a drilled hole or affixation of a prosthetic or implant in a prepared patient situation. | 07-16-2015 |
20150202009 | STERILE DRAPE AND ADAPTER FOR COVERING A ROBOTIC SURGICAL ARM AND PREVENTING CONTAMINATION OF A STERILE FIELD - Described herein are a sterile drape and adapter for use with a robotic surgical system, for example, during spinal surgery. In certain embodiments, the sterile drape and adapter cover a robotic surgical arm and prevent contamination of a sterile field. The sterile drape may attached to the robotic arm via a sterile adapter that ensures the drape is tightly stretched over the tool holder and robot interface to provide a structure that provides for repeatable and rigid positioning of the sterile drape. Tightly stretching the drape over the sterile adapter and tightening the tool holder to the robotic arm using, for example, a tightening screw, reduces the likelihood of folds in the drape between the tool holder and robot interface. Thus, errors between the robot model and the actual situation because of the position of the tool holder relative to the robot interface are minimized. | 07-23-2015 |
20150223897 | STERILE HANDLE FOR CONTROLLING A ROBOTIC SURGICAL SYSTEM FROM A STERILE FIELD - Described herein are a sterile handle for use with a robotic surgical system, for example, during spinal surgery. In certain embodiments, the sterile handle adds functionalities and an interface to existing surgical tools such that the robotic system may be commanded from the sterile field during surgery. The sterile handle permits a user, such as a surgeon, to physically manipulate the location of the end-effector of a robotic surgical system. The sterile handle may include an input device that allows the user to limit the movement of the end-effector, such as limiting the movement to translations or rotations only. The sterile handle may detect the presence of a user's hand. This ensures the end-effector is only moved when the user manipulates the sterile handle and reduces the likelihood that the end-effector is moved unintentionally. | 08-13-2015 |
20150366624 | SYSTEMS AND METHODS FOR PERFORMING MINIMALLY INVASIVE SURGERY - Minimally invasive surgical techniques are used to obtain access to vertebrae while protecting soft tissues in the surrounding area. The dilators may be used to provide a working channel through which the operation is performed. Standard dilators may be used with a robotic surgical system to provide precise guidance of surgical tools. A dilator may be held by the robot and automatically repositioned when the surgeon adjusts a trajectory for performing the surgery. The dilator itself may be used as a surgical instrument guide along with dilator adaptors that adjust the diameter of a portion of the dilator to allow for different sized tools to be guided by the dilator. Alternatively, surgical instrument guides may also be held by the robotic arm such that tools are guided by a surgical instrument guide through the dilator to perform a medical procedure. | 12-24-2015 |
20160081754 | APPARATUS, SYSTEMS, AND METHODS FOR PRECISE GUIDANCE OF SURGICAL TOOLS - Described herein are systems, apparatus, and methods for precise placement and guidance of tools during a surgical procedure, particularly a spinal surgical procedure. The system features a portable robot arm with end effector for precise positioning of a surgical tool. The system requires only minimal training by surgeons/operators, is intuitive to use, and has a small footprint with significantly reduced obstruction of the operating table. The system works with existing, standard surgical tools, does not required increased surgical time or preparatory time, and safely provides the enhanced precision achievable by robotic-assisted systems. | 03-24-2016 |
Erich Nussbaumer, Nals IT
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20140005821 | PRODUCTION INSTALLATION WITH TIME-INDEXED HISTORICAL DISPLAY | 01-02-2014 |
20140101941 | METHOD AND DEVICE FOR CONTINUOUSLY PRODUCING A MESH-TYPE SUPPORT - Method for continuously producing a mesh-type support by welding a lower member arrangement, which comprises at least one lower member, in particular two lower members, and an upper member, which is arranged at a specific height in relation to the lower member arrangement, and has at least one diagonal member running back and forth between the at least one lower member and the upper member, in particular in a zigzagging form, wherein the welding of the at least one lower member and the upper member to the at least one diagonal member is performed by means of a lower-member welding device and an upper-member welding device, wherein the height of the upper member in relation to the lower member arrangement is changed during the continuous production of the mesh-type support. The invention also relates to a device for carrying out the method. | 04-17-2014 |
Hannes Nussbaumer, Stein CH
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20160108001 | PROCESS FOR THE STEREOSELECTIVE PREPARATION OF A PYRAZOLE-CARBOXAMIDE - The present invention relates to a process for the enantioselective preparation of the compound of formula (Ib), which process comprises a) reducing the (E)- or (Z)-form of a compound of formula (II), with an enantioselective reagent to a compound of formula (IIIa), and b) acylating the compound of formula (IIIa) with the compound of formula (IV), or c) coupling the compound of formula (IV) with the compound of formula (II), to give a compound of formula (V) and d) reducing compound of formula (V) in the presence of hydrogen, a catalyst and a chiral ligand, to the compound of formula (Ib). | 04-21-2016 |
Jochen Nussbaumer, Waldstetten DE
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20100236860 | Electric power steering - An electric power steering system, and in particular a power-assisted steering system for a vehicle, comprises a steering transmission housing and a housing cover which forms an axial closure of the steering transmission housing and which is penetrated by an axially displaceable component of the steering transmission. In order to provide an electric power steering system which is easy to assemble and is not susceptible to wear, in an axially outer region of the housing cover, a first guide bushing for the axially displaceable component is integrated in the housing cover. | 09-23-2010 |
John Nussbaumer, Bolivar, OH US
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20140350290 | LIGHT-COLORED METAL WORKING ADDITIVES - A composition having a compound having the structure: | 11-27-2014 |
Karen Nussbaumer, New Rochelle, NY US
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20090088624 | Methods and Apparatus for Diagnosing and Treating Aneurysms - A method of developing a diagnosis and prognosis for an aneurysm in order to determine a procedure for treating the aneurysm. The method includes determining a first diameter of a blood vessel at a first location proximal to an aneurysm, and determining a second diameter of the blood vessel at a second location. The second location incorporates at least a portion of the aneurysm. Next, the ratio of the second diameter to the first diameter is calculated. And, a prognosis of the aneurysm, and a determination of the treatment for the aneurysm, may then be determined based on the ratio. | 04-02-2009 |
Markus Nussbaumer, Kirchberg CH
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20130177694 | Method for Producing Maize Flour - This invention provides a novel method for producing maize flour including at least one treatment step in which a product comprising maize is treated under alkaline conditions, wherein an alkaline solution is sprayed onto the product. Furthermore, a facility for producing maize flour is disclosed, in particular in said method. Moreover, maize flour obtained by this method and foodstuffs containing this flour are disclosed. | 07-11-2013 |
20140065280 | Method for Treating a Starchy Food - A starchy food having an initial moisture content in the range from 20% wb to 35% wb. is passed through states in which the food surface has various pairs temperature and surface moisture values. Then, the starchy food is brought to and maintained at a temperature in such a manner that a degree of gelatinization of at least 75% is achieved. Then, the surface is cooled to a temperature below the temperature T | 03-06-2014 |
20150208698 | METHOD FOR PRODUCING MAIZE FLOUR - This invention provides a novel method for producing maize flour including at least one treatment step in which a product comprising maize is treated under alkaline conditions, wherein an alkaline solution is sprayed onto the product. Furthermore, a facility for producing maize flour is disclosed, in particular in said method. Moreover, maize flour obtained by this method and foodstuffs containing this flour are disclosed. | 07-30-2015 |
Peter Nussbaumer, Dortmund DE
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20130079345 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES - The present invention relates to disubstituted triazine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said disubstituted triazine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said disubstituted triazine derivatives as inhibitors for a protein kinase. | 03-28-2013 |
20140179662 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES - The present invention relates to disubstituted triazine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said disubstituted triazine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said disubstituted triazine derivatives as inhibitors for a protein kinase. | 06-26-2014 |
20140296304 | Pharmaceutically Active Disubstituted Pyridine Derivatives - The present invention relates to disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said disubstituted pyridine derivatives as inhibitors for a protein kinase. | 10-02-2014 |
20140316104 | CYCLOSPORIN DERIVATIVES - The present invention relates to novel cyclosporin derivatives that do not cross the cellular membrane. The compounds according to the invention are used in medicine, more particularly in the treatment/diagnosis of acute and chronic inflammatory diseases, viral infections, cancer, degenerative muscle diseases, neurodegenerative diseases and damage that is associated with calcium homeostasis impairment. The novel cyclosporin derivatives additionally have no immunosuppressive effect. | 10-23-2014 |
20150111873 | PHARMACEUTICALLY ACTIVE PYRAZOLO-TRIAZINE DERIVATIVES - Pyrazolo[1,5-a][1,3,5]triazine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said pyrazolo[1,5-a][1,3,5]triazine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors for a protein kinase. | 04-23-2015 |
Thomas Nussbaumer, Zuerich CH
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20110025154 | Electric rotary drive - An electric rotary drive is proposed, designed as a bearingless external rotor motor, having a magnetically supported, substantially ring-shaped rotor ( | 02-03-2011 |
20110031836 | Rotational machine, method for the determination of a tilting of a rotor of a rotational machine, as well as a processing plant - The invention relates to a rotational machine adapted as a bearing-free engine including a stator ( | 02-10-2011 |
20110187217 | Magnetic bearing apparatus - A magnetic bearing apparatus is proposed having a stator ( | 08-04-2011 |
Werner Nussbaumer, Leifers IT
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20140223622 | Apple Tree named 'Stark Gugger' - Borkh ‘Stark Gugger’ variety is distinguished from the ‘Starking Delicious’ variety and other Red Delicious varieties by the a unique combination of characteristics including purple red fruits with solid flush coloration on 100% of the surface, a fruit shape that is long truncated-conical with pronounced crowning at distal end, fruit coloration that starts 10 days earlier than other Red Delicious varieties; an anticipation of fruit maturation of 5-7 days compared to other Red Delicious variety and a growth habit that is standard (not spur) 20% stronger than other Red Delicious standard. | 08-07-2014 |
William Nussbaumer, Baltimore, MD US
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20110244457 | IMMUNO-AMPLIFICATION - A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte. | 10-06-2011 |
20150152473 | IMMUNO-AMPLIFICATION - A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte. | 06-04-2015 |
William A. Nussbaumer, Lutherville, MD US
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20110105350 | DIAGNOSIS OF SEPSIS - Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set. | 05-05-2011 |
20140141435 | DIAGNOSIS OF SEPSIS - Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set. | 05-22-2014 |
William A. Nussbaumer, Baltimore, MD US
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20090104605 | DIAGNOSIS OF SEPSIS - Methods and apparatus for predicting the development of sepsis in a subject at risk for developing sepsis are provided. Features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods and apparatus for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. A plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods and apparatus for diagnosing sepsis in a subject are provided. A plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set. | 04-23-2009 |