Patent application number | Description | Published |
20100291147 | RECOMBINANT RSV ANTIGENS - This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g., vaccines) for the treatment and/or prevention of RSV infection. | 11-18-2010 |
20110177117 | CHIMERIC RESPIRATORY SYNCYTIAL VIRUS POLYPEPTIDE ANTIGENS - Chimeric respiratory syncytial virus (RSV) polypeptide antigens are provided. The disclosed polypeptides include a first amino acid sequence comprising an F2 domain uncleavably joined to an F1 domain of a Respiratory Syncytial Virus (RSV) Fusion (F) protein polypeptide; and a second amino acid sequence comprising a portion of an RSV Attachment (G) protein polypeptide comprising an immunologically dominant epitope. The disclosure also provides nucleic acids that encode, and pharmaceutical compositions that contain, the chimeric RSV polypeptides, as well as methods for their production and use. | 07-21-2011 |
20120070491 | CASB7439 CONSTRUCTS - The present disclosure relates to compounds and methods for increasing the recombinant production of CASB7439 polypeptides, and for methods of utilizing the same. | 03-22-2012 |
20120093847 | RECOMBINANT RSV VACCINES - This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g., vaccines) for the treatment and/or prevention of RSV infection. | 04-19-2012 |
20120135028 | VACCINE - The present disclosure provides immunogenic compositions that include at least two paramyxovirus F protein antigens selected from human metapnuemovirus (hMPV), paarainfluenza virus (PIV) and respiratory syncytial virus (RSV). The antigens of the disclosed compositions are recombinant F protein polypeptides, which have been modified to stabilize the trimeric prefusion conformation. Nucleic acids encoding the antigens, as well as methods for their production and use are also provided. | 05-31-2012 |
20120289688 | EXPRESSION SYSTEM - Polynucleotides are provided herein. | 11-15-2012 |
20120294882 | MODIFIED TUBERCULOSIS ANTIGENS - Modified Rv3616c proteins and their use as medicaments, particularly for the prevention of reactivation of tuberculosis. | 11-22-2012 |
20130123472 | NOVEL ANTIGEN BINDING PROTEINS - Antigen binding proteins, such as antibodies, which bind to human MAGE-A3, polynucleotides encoding such antigen binding proteins, and uses and manufacture thereof. | 05-16-2013 |
20130216613 | CYTOMEGALOVIRUS GB ANTIGEN - The invention relates to a cytomegalovirus (CMV) gB polypeptide comprising at least a portion of a gB protein extracellular domain comprising a fusion loop 1 (FL1) domain and a fusion loop 2 (FL2) domain, wherein at least one of the FL1 and FL2 domains comprises at least one amino acid deletion or substitution. | 08-22-2013 |
20130224266 | IMMUNOGENIC COMPOSITION - The present invention relates to the use of a immunogenic or immunostimulatory composition comprising a | 08-29-2013 |
20140056934 | FUSION PROTEINS AND COMBINATION VACCINES COMPRISING HAEMOPHILUS INFLUENZAE PROTEIN E AND PILIN A - The present invention relates to compositions comprising | 02-27-2014 |