Nightingale
Andrew Mark Nightingale, Sawston GB
Patent application number | Description | Published |
---|---|---|
20090070493 | Interconnect component and device configuration generation - A method of generating a configuration of an integrated circuit | 03-12-2009 |
Andrew Mark Nightingale, Cambridge GB
Patent application number | Description | Published |
---|---|---|
20080313587 | Apparatus and method for performing a sequence of verification tests to verify a design of a data processing system - An apparatus and method are provided for performing a sequence of verification tests to verify the design of a data processing system. The apparatus comprises a system under verification representing the design of the data processing system, the system under verification including a component model representing at least one hardware component of the data processing system. The component model includes an interface module through which the component model interacts with other portions of the system under verification during performance of the verification tests. An alternative model is provided for representing the hardware component for selected verification tests, and the interface module comprises a verification interface module which is responsive to switch criteria specified by the alternative model to switch in the alternative model in place of the component model. Accordingly, by such an approach, the alternative model can take the place of the component model during performance of the selected verification tests. This maintains system integrity of the system under verification, whilst providing a simple and effective mechanism for enabling the alternative model to take the place of the component model for certain specific verification tests, for example when testing corner cases in the design. | 12-18-2008 |
Chris Earl Nightingale, Auckland NZ
Patent application number | Description | Published |
---|---|---|
20100078028 | PATIENT INTERFACES - The present invention relates to a device for delivering a supply of gases to a patient. The device includes a patient interface and connecting member. The connecting member is preferably a L-shaped swivelled connector that is capable of being fixed into one of two positions, a first position where the connector is freely rotatable within the patient interface, and a second position where an interference between the interface and connector prevents the free rotation of the connector within the patient interface. The present invention further relates to a connector that has outlet means, which includes at least one outlet vent and a funnel, which in use directs and passes a substantial portion gases expired from the patient through the outlet vent or vents. | 04-01-2010 |
20130068228 | PATIENT INTERFACES - The present invention relates to a device for delivering a supply of gases to a patient. The device includes a patient interface and connecting member. The connecting member is preferably a L-shaped swiveled connector that is capable of being fixed into one of two positions, a first position where the connector is freely rotatable within the patient interface, and a second position where an interference between the interface and connector prevents the free rotation of the connector within the patient interface, The present invention further relates to a connector that has outlet means, which includes at least one outlet vent and a funnel, which in use directs and passes a substantial portion gases expired from the patient through the outlet vent or vents. | 03-21-2013 |
Chris Earl Nightingale, Lodon GB
Patent application number | Description | Published |
---|---|---|
20100024825 | PATIENT INTERFACES - The present invention relates to a device for delivering a supply of gases to a patient. The device includes a patient interface and connecting member. The connecting member is preferably a L-shaped swivelled connector that is capable of being fixed into one of two positions, a first position where the connector is freely rotatable within the patient interface, and a second position where an interference between the interface and connector prevents the free rotation of the connector within the patient interface. The present invention further relates to a connector that has outlet means, which includes at least one outlet vent and a funnel, which in use directs and passes a substantial portion gases expired from the patient through the outlet vent or vents. | 02-04-2010 |
Christopher Earl Nightingale, Auckland NZ
Patent application number | Description | Published |
---|---|---|
20100288280 | BREATHING ASSISTANCE APPARATUS - A patient interface that is comfortable for a user to wear is disclosed. The patient interface includes a forehead rest and cushion. In particular the cushion includes a deformable resilient member that when compressed creates a uniformly and gradually increasing force while evenly distributing the pressure on the forehead of the patient. | 11-18-2010 |
20120318270 | NASAL INTERFACE - A nasal cannula for use in a system for providing a flow of respiratory gases to a user is described. The nasal cannula comprises a body made from a pliable material. The body has an inlet and at least one nasal prong fluidly connected to the inlet. In use a conduit providing a flow of gases to the cannula is connected to the inlet, and the nasal prong is inserted into a user's nostril. The cannula is arranged to direct the flow of gases from the nasal prong towards the front wall of the user's nasal passage within the user's nose. | 12-20-2012 |
20130133656 | APPARATUS AND METHOD FOR PROVIDING GASES TO A USER - Apparatus and methods are disclosed for controlling pressure delivery to a user such as a patient. A flow generator generates an outlet flow at an outlet port for delivery to a patient. At least one sensor measures properties of the flow of gas at the outlet port or being delivered to the patient. A controller is operatively connected to the flow generator and the at least one sensor, and is adapted to operate according to a pressure control mode in which the controller controls the flow generator to output a substantially steady pressure or a flow control mode in which the controller controls the flow generator to output a substantially steady flow. The controller operates in the flow control mode when a patient may be awake and in the pressure control mode when the patient may be asleep. | 05-30-2013 |
20140230813 | BREATHING ASSISTANCE APPARATUS - A CPAP system for supplying humidified gases to a user is disclosed in which various interfaces are described for gas delivery. A mask cushion including a deformable cushion and thin sheath is described. | 08-21-2014 |
20140318548 | MASK - A mask is disclosed that has a gas outlet which is quiet and provides for a diffused outlet flow of gases. The outlet is preferably a slot formed between a hollow body and cover over said hollow body. The mask also preferably extends and seals under a user's chin in use. | 10-30-2014 |
20150273169 | PATIENT INTERFACES - The present invention relates to a device for delivering a supply of gases to a patient. The device includes a patient interface and connecting member. The connecting member is preferably a L-shaped swiveled connector that is capable of being fixed into one of two positions, a first position where the connector is freely rotatable within the patient interface, and a second position where an interference between the interface and connector prevents the free rotation of the connector within the patient interface, The present invention further relates to a connector that has outlet means, which includes at least one outlet vent and a funnel, which in use directs and passes a substantial portion gases expired from the patient through the outlet vent or vents. | 10-01-2015 |
20160001030 | BREATHING ASSISTANCE APPARATUS - A patient interface that is comfortable for a user to wear is disclosed. The patient interface includes a forehead rest and cushion. In particular the cushion includes a deformable resilient member that when compressed creates a uniformly and gradually increasing force while evenly distributing the pressure on the forehead of the patient. | 01-07-2016 |
20160022945 | BREATHING ASSISTANCE APPARATUS - A patient interface that is comfortable for a user to wear is disclosed. The patient interface includes a forehead rest and cushion. In particular the cushion includes a deformable resilient member that when compressed creates a uniformly and gradually increasing force while evenly distributing the pressure on the forehead of the patient. | 01-28-2016 |
20160051785 | MASK - A mask is disclosed that has a gas outlet which is quiet and provides for a diffused outlet flow of gases. The outlet is preferably a slot formed between a hollow body and cover over said hollow body. The mask also preferably extends and seals under a user's chin in use. | 02-25-2016 |
Christopher Earl Nightingale, London GB
Patent application number | Description | Published |
---|---|---|
20120318269 | BREATHING ASSISTANCE APPARATUS - A patient interface that is comfortable for a user to wear is disclosed. The patient interface includes a forehead rest and cushion. In particular the cushion includes a deformable resilient member that when compressed creates a uniformly and gradually increasing force while evenly distributing the pressure on the forehead of the patient. | 12-20-2012 |
Christopher G.e. Nightingale, Singapore SG
Patent application number | Description | Published |
---|---|---|
20110162290 | Photovoltaic Cell Support Assembly - A photovoltaic cell support assembly ( | 07-07-2011 |
20110162693 | Connection System for a Solar Electric Power Conversion System - A connection system | 07-07-2011 |
Hugo Nightingale, Coventry, Warwickshire GB
Patent application number | Description | Published |
---|---|---|
20160046145 | IMPROVEMENTS RELATING TO VEHICLE WHEELS - An insert for a vehicle wheel having a plurality of spokes which define, in part, an outwardly-facing wheel surface, and further define between adjacent ones of the spokes, a cavity for receiving the insert, in use, the insert comprising: an outer profile of complementary shape to the cavity and arranged to fit securely within the cavity, in use; and a flow redirecting surface which is aerodynamically shaped so as to reduce drag on an adjacent spoke of the wheel, in use. | 02-18-2016 |
Hugo Nightingale, Leamington Spa GB
Patent application number | Description | Published |
---|---|---|
20150345578 | BRAKE COOLING - The present invention relates to a brake cooling system ( | 12-03-2015 |
Peter David Nightingale, Pune IN
Patent application number | Description | Published |
---|---|---|
20150344919 | PROCESS FOR THE PREPARATION OF PREGABALIN - The present invention provides an improved process for the preparation of a compound of formula (I), which comprises the steps of: formula (I), (a) reacting isovaleraldehyde of formula (II) and alkyl cyanoacetate of formula (III) optionally in presence of salts of weak acid and weak base or weak base in a suitable solvent to get 2-cyano-5-methyl-hex-2-enoic acid alkyl ester of formula (IV); (b) reacting 2-cyano-5-methyl-hex-2-enoic acid alkyl ester of formula (IV) with a suitable cyanide source in water or in an organic solvent or mixture thereof to get 2-isobutylsuccinonitrile of formula (V); (c) obtaining optionally 2-isobutylsuccinonitrile of formula (V) by reacting isovaleraldehyde of formula (II) and alkyl cyanoacetate of formula (III) in presence of suitable cyanide source in water or in an organic solvent or mixture thereof in single step; (d) converting 2-isobutylsuccinonitrile of formula pa (V) to racemic 3-cyano-5-methyl-hexanoic acid or salt thereof of formula (VI) with a genetically modified nitrilase enzyme (Nit pt 9N_56_2) in water or optionally with an organic co-solvent at appropriate pH and temperature; (e) converting racemic 3-cyano-5-methyl-hexanoic acid or salt thereof of formula (VI) to racemic alkyl 3-cyano-5-methyl-hexanoate of formula (VII) by treatment with alcohol (R3OH) and acidic catalyst or alkyl halide (R3X) in presence of a base in a suitable solvent or a mixture of solvents thereof; (f) obtaining (S)-alkyl 3-cyano-5-methyl-hexanoate of formula (VIII) and (R)-3-cyano-5-methyl-hexanoic acid or salt thereof of formula (X) by enzymatic enantioselective hydrolysis in water or organic solvent or a mixture thereof from racemic alkyl 3-cyano-5-methyl-hexanoate of formula (VII); (g) obtaining optionally the compound of formula (VII) by racemizing unwanted (R)-3-cyano-5-methyl-hexanoic acid or salt thereof of formula (X) or substantially enriched (R)-3-cyano-5-methyl-hexanoic acid salt thereof of formula (X) in presence of a base in organic solvent or a mixture thereof; (h) converting (S)-alkyl 3-cyano-5-methyl-hexanoate of formula (VIII) to pregabalin of formula (I) by hydrolyzing ester group with suitable alkali or alkaline earth metal base followed by hydrogenation optionally in one pot in a solvent selected from water or other organic solvents or a mixture thereof in presence of a suitable hydrogenation catalyst. | 12-03-2015 |
Peter Karl Nightingale, Birmingham GB
Patent application number | Description | Published |
---|---|---|
20090149343 | HISTONES - A histone microarray comprising a substrate support functionalised with at least two probe molecules each comprising a sequence derived from a histone protein, or isoform, or variant, or modification thereof. A histone microarray in which probe molecules have sequences derived from different histone proteins. The histone microarray of the invention can be used in methods for screening and characterising antibodies exhibiting binding specificity for histones and to specific histone modifications, as well as methods for screening and characterising the effects of histone modifications on the activity and binding of histone specific enzymes and binding proteins. | 06-11-2009 |
Ray Nightingale, Munchengladbach DE
Patent application number | Description | Published |
---|---|---|
20110231645 | SYSTEM AND METHOD TO VALIDATE AND AUTHENTICATE DIGITAL DATA - A system and method combining registration with a trusted third party, certificate generation, hashing, encryption, customizable file identification fields, and time-stamping technology with recognized “best practice” procedures to achieve the legal admissibility and evidential weight of any form of digital file or collection of digital files. Generally, the originator of the file (the first party) and the originator's employing organization are registered with a Trusted Third Party. The originator reduces the file, by means of a hashing algorithm, to a fixed bit length binary pattern. This provides a unique digital fingerprint of the file. The resultant hash value, the originator's identity details, the employing organization details associated and securely linked to the digital certificate, the title of the file, customizable file identification fields, and other relevant data are forwarded to a Trusted Third Party where the date and time from a known and trusted time source are added. The customizable file identification fields can provide the originator with a mechanism for configuring the seal to incorporate as much additional information as deemed necessary to prove the authenticity of the digital content and/or provide data for the purposes of adding value in functions such as source identification, sorting, analysis, investigation, and compliance. Such information could include, but would not be limited to, location/GPS coordinates, machine id, biometric information, smart-card data, reason for sealing. The original file does not leave the control of the originating party. When combined, the forwarded details and date and time create a Seal Record. The Seal Record is encrypted and hashed. The Seal Record along with all other relevant information are retained on a central secure server. The recipient of the file (the second party) can confirm the file has been received in an unaltered state with integrity retained and it is the authentic version by validating the file. | 09-22-2011 |
Scott Nightingale, New South Wales AU
Patent application number | Description | Published |
---|---|---|
20090265956 | SOLE ASSEMBLY - A sole assembly suitable for use in footwear, the sole assembly including a flexible base ( | 10-29-2009 |
Shaun Nightingale, London GB
Patent application number | Description | Published |
---|---|---|
20090126067 | HAIRCUT APRON - A vest having a head aperture for placement around the neck of a wearer, wherein a circumferential seal of flexible elastomeric waterproof material is welded to the head aperture, the vest further comprising an adjustable releasable fastener secured to opposite sides of a substantially radial slit extending through the seal, the slit and fastener enabling the seal to be adjusted and secured to accommodate wearers of differing neck circumference, characterized in that the circumferential seal is an annulus, welded to and in the same plane as the vest, and having a flexibility, resilience and width such that the seal self-conforms upwardly to the neck when fastened, forming a waterproof contact band. | 05-21-2009 |
Stephen James Nightingale, Surrey GB
Patent application number | Description | Published |
---|---|---|
20110263195 | USE OF STEERING SIGNALS IN INTERFERENCE CANCELLATION WITH APPLICATION TO COMMUNICATION THROUGH SIGNAL JAMMING - A system and method are provided for transmitting a broadband interference signal and allowing communication through the transmitted interference signal. The system includes an interference transmitter for transmitting the interference signal, the interference transmitter having a transmitter feeder and a first antenna; a radio receiver for receiving a radio signal, the radio receiver having a radio feeder and a second antenna collocated with the first antenna of the interference transmitter; a steering signal generator for introducing at least one steering signal into the interference signal at the transmit feeder; a first directional coupler for sampling a portion of the interference signal that includes at least one of the steering signals; a negative feedback loop for adjusting the amplitude and phase of the sampled portion of the interference signal; and a second directional coupler for coupling the adjusted sampled portion of the interference signal into the radio feeder. | 10-27-2011 |