Nicholas F.
Nicholas F. Buccheri, Florham Park, NJ US
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20120112870 | THERMAL PROTECTION DEVICE AND METHOD - A solenoid valve for use in a hazardous environment requiring a surface temperature of the valve to not exceed a cutoff temperature, the valve comprising coil configured to physically move an armature using an field generated by the coil; a thermal cutoff device having a fusing temperature above the cutoff temperature; and a heating resistor sized and configured to raise thermal cutoff device's temperature to the fusing temperature before the surface temperature exceeds the cutoff temperature. A method of constructing a solenoid valve for use in a hazardous environment requiring a surface temperature of the valve to not exceed a cutoff temperature, the method comprising the steps of: selecting a thermal cutoff device having a fusing temperature above the cutoff temperature; and selecting and configuring a heating resistor to raise thermal cutoff device's temperature to the fusing temperature before the surface temperature exceeds the cutoff temperature. | 05-10-2012 |
Nicholas F. Covello, Iii, Chicago, IL US
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20150363751 | Methods For Matchmaking - A method is provided for matching a plurality of users of a matchmaking system. The method has a step of providing a matchmaking system with a collection portal for collecting characteristic information from a first and second user of the system. The system further has an aggregator in communication with the collection portal. The aggregator is for creating an aggregated database comprising the characteristic information of the first user and the characteristic information of the second user. The method has another step of collecting characteristic information from the first user and the second user through the collection portal. The method has another step of creating an aggregated comprising the characteristic information. The method further has the step of verifying attendance information for at least one of the first and second users at an event. The method has a step of updating the aggregated database based on the attendance information. | 12-17-2015 |
Nicholas F. Jungels, Champaign, IL US
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20140204299 | LOCAL BUFFERS IN A LIQUID CRYSTAL ON SILICON CHIP - An example embodiment includes a liquid crystal on silicon (LCOS) system. The LCOS system includes multiple pixels, a pixel voltage supply source (voltage source), an external buffer, and a local buffer. The voltage source is configured to supply an analog ramp to the pixels. The external buffer is configured to buffer the voltage source from the pixels. The local buffer is configured to buffer the external buffer from a subset of pixels of the plurality of pixels. | 07-24-2014 |
20140204330 | PIPELINED PIXEL APPLICATIONS IN LIQUID CRYSTAL ON SILICON CHIP - An example embodiment includes a LCOS IC. The LCOS IC includes multiple pixels, a column driver, and multiple conductive lines. The pixels are arranged in a pixel array. The column driver is configured to supply multiple signals to a column of pixels included in the pixel array. Each of the conductive lines couples the column driver to a subset of pixels in the column of pixels. The conductive lines are configured such that two or more of the signals can be supplied to two or more of the subsets of pixels with some overlapping duration. | 07-24-2014 |
Nicholas F. Jungels, Gilbert, AZ US
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20090092214 | CLOCK CIRCUIT WITH CLOCK TRANSFER CAPABILITY AND METHOD - An apparatus including a multiplexer configured to provide an output clock selected from a source clock, a destination clock, and a transition clock is provided. The apparatus further includes a phase difference calculation module configured to calculate a phase difference between the source clock and the destination clock and a clock generation module configured to generate a plurality of clocks. The apparatus further includes a clock selection module configured to select one of the plurality of clocks as the transition clock and a control circuit configured to provide: (1) a signal to the clock selection module for selecting one of the plurality of clocks as the transition clock based on the phase difference between the source clock and the destination clock and (2) a signal to the multiplexer to provide as the output clock one of the source clock, the destination clock, or the transition clock. | 04-09-2009 |
Nicholas F. Larusso, Rochester, MN US
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20090170754 | TREATING LIVER DISEASES - This document provides methods and materials related to treating liver conditions. For example, the methods and materials relating to the use of cAMP inhibitors to treat liver conditions are provided. | 07-02-2009 |
20120277153 | TREATING LIVER DISEASES - This document provides methods and materials related to treating liver conditions. For example, the methods and materials relating to the use of cAMP inhibitors to treat liver conditions are provided. | 11-01-2012 |
20130178522 | VITAMIN C AND CHROMIUM-FREE VITAMIN K, AND COMPOSITIONS THEREOF FOR TREATING AN NFKB-MEDIATED CONDITION OR DISEASE - Provided herein is a pharmaceutical composition comprising vitamin C and chromium-free vitamin K, and optionally one or more pharmaceutically acceptable excipient(s). Also provided herein is a chromium-free pharmaceutical composition comprising vitamin C and vitamin K, and optionally one or more pharmaceutically acceptable excipient(s). Further provided herein is a method of treating, preventing, or managing an NFKB-mediated condition, disorder, or disease, comprising administering to the subject a therapeutically effective amount of vitamin C and chromium-free vitamin K. | 07-11-2013 |
20140200270 | VITAMINS C AND K FOR TREATING POLYCYSTIC DISEASES - Provided herein are methods for treating, preventing, or ameliorating one or more symptoms of a polycystic disease in a subject, comprising administering to the subject a therapeutically effective amount of vitamins C and K. | 07-17-2014 |
20150119413 | TREATMENT OF POLYCYSTIC DISEASES WITH AN HDAC6 INHIBITOR - An HDAC6-specific inhibitor (i.e., a compound of Formula I or II) is shown to reduce the pathogenesis associated with polycystic disease. Administration of an HDAC6-specific inhibitor attenuated many of the symptoms characteristic of polycystic liver disease including cyst formation, cyst growth and cholangiocyte proliferation. Treatment with a HDAC6-specific inhibitor also increased the amount of bile duct acetylated tubulin and β-catenin phosphorylation and/or acetylation while reducing bile duct β-catenin synthesis. These results demonstrate that HDAC6 is overexpressed in cystic cholangiocytes and that its pharmacological inhibition reduces cholangiocyte proliferation and cyst growth. | 04-30-2015 |
20150258179 | TREATING LIVER DISEASES - This document provides methods and materials related to treating liver conditions. For example, the methods and materials relating to the use of cAMP inhibitors to treat liver conditions are provided. | 09-17-2015 |
Nicholas F. Materer, Stillwater, OK US
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20090058427 | PASSIVE WIRELESS CORROSION SENSOR - A passive wireless corrosion sensor is disclosed. A circuit is configured to provide a signal response when energized. An antenna is configured to wirelessly receive energy for energizing the circuit and to receive the signal response from the circuit and transmit the signal response. A corrosion sensitive connector interposes the circuit and the antenna. The corrosion sensitive connector conducts the energy from the antenna to the circuit and conducts the signal response from the circuit to the antenna when in a substantially non-corroded state. The corrosion sensitive connector creates an effectively non conducting link between the antenna and the circuit when in a substantially corroded state. | 03-05-2009 |
Nicholas F. Maxemchuk, Mountainside, NJ US
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20100002583 | Systems And Methods For Modeling A Mobile Ad Hoc Wireless Network - Systems and methods for modeling a mobile ad hoc wireless network are disclosed herein. In some embodiments of the disclosed subject matter, methods for modeling a mobile ad hoc wireless network for a predetermined geographical area. An exemplary method includes dividing the geographic area into a network grid including a plurality of network grid elements, locating obstacles, if any, to communication between transmission nodes located in at least two different grid elements from the plurality of network grid elements, locating bottlenecks within the plurality of network grid elements, locating network grid elements from the plurality of network grid elements where wireless transmission is unconstricted, determining a transmission flow rate across the bottlenecks, and comparing the transmission flow rate across the bottlenecks to determine if any of the bottlenecks are not real bottlenecks. | 01-07-2010 |
20100091834 | SYSTEMS AND METHODS FOR TELESCOPIC DATA COMPRESSION IN SENSOR NETWORKS - Systems and methods for telescopic data compression in sensor networks are disclosed herein. An exemplary method of the disclosed subject matter for telescopically compressing data received from a plurality of sensors in a network adapted to detect a field includes broadcasting a first set of sampling positions to sensors, forming a first set of clusters of sensors based on the sampling positions, receiving data from the sensors contained within the clusters, performing local interpolation of the received data, reconstructing a representation of the field using the interpolated data, and determining areas of interest based on the reconstructed representation of the field. | 04-15-2010 |
20100223332 | SYSTEMS AND METHODS FOR IMPLEMENTING RELIABLE NEIGHBORCAST PROTOCOL - Methods and systems for vehicle-to-vehicle communications where vehicles can communicate one or more of speed, position, direction, acceleration and state in order to coordinate or control their operation are disclosed herein. In some embodiments of the disclosed subject matter, methods for vehicle-to-vehicle communications where vehicles can communicate one or more of speed, position and state in order to coordinate or control their operation. An exemplary method includes creating moving broadcasting groups which groups can move with the flow of traffic, adjust the span of the group and maintain minimum overlap size between adjacent broadcasting groups, combining two or more vehicles within one or more broadcasting groups, within some specified distance into neighborhoods, transmitting information about one or more of speed, position and state of vehicles in the neighborhood to the other vehicles in said neighborhood; receiving information about speed, position and state by vehicles in the neighborhood from the other vehicles in said neighborhood, filtering out duplicate information and information received from vehicles that are not in the same neighborhood, providing that two or more vehicles in the same neighborhood have substantially continuous communication capacity by maintaining the size of overlap between adjacent neighborhoods, avoiding delays in entering the new neighborhood by extending the overlap size, and utilizing one or more guarantees provided by an underlying reliable broadcast communication layer by transferring said guarantees to corresponding one or more neighborhoods. | 09-02-2010 |
Nicholas F. O'Neill, Wilmington, NC US
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20150318063 | SYSTEMS AND METHODS FOR REDUCING SURFACE DEPOSITION AND CONTAMINATION - Mobile apparatuses move within contaminated fluid to create fluid flows against structures that remove and prevent contaminant deposition on structure surfaces immersed in the fluid. Unsettling flows in water may exceed approximately 2 m/s for radionuclide particles and solutes found in nuclear power plants. Mobile apparatuses include pressurized liquid from a pump or pressurized source that can be chemically and thermally treated to maximize deposition removal. When spraying the pressurized liquid to create the deposition-removing flow, mobile apparatuses may be self-propelled within the fluid about an entire surface to be cleaned. Mobile apparatuses include filters keyed to remove the contaminants moved into the coolant by the flow, and by taking in ambient fluid, enable such filtering of the ambient fluid along with a larger flow volume and propulsion. Propulsion and the pressurized liquid in turn enhance intake of ambient fluid. | 11-05-2015 |
Nicholas F. Paoni, Encinitas, CA US
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20110184712 | PREDICTIVE MODELS AND METHODS FOR DIAGNOSING AND ASSESSING CORONARY ARTERY DISEASE - Biomarkers useful for diagnosing and assessing the extent of coronary artery disease (CAD) are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. In a preferred embodiment, the biomarkers are organized into clustered groups. The expression level of the biomarkers within a group are highly correlated to each other in normal and disease states. Expression values of genes chosen from each of two, three, four or five of the clustered gene groups, A, B, C, D, E may be used. Alternatively, expression values of genes chosen from the groups are combined into a metagene. Preferred biomarkers include S100A12, S100A8, S100A9, BCL2A1, and F5 (group A); XK, P62, and FECH (group B); TUBB2 (group C); IFNG, PDGFB, VSIG4, and TNF (group D); CSF3R, TLR5, CD46, and NCF1 (group E); S100A12, S100A9, BCL2A1, TXN and CSTA (group I); OLIG1, OLIG2, ADORA3, CLC, and SLC29A1 (group II); and CBS and ARG1 (group IV). | 07-28-2011 |
Nicholas F. Paoni, Belmont, CA US
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20090197301 | Secreted and transmembrane polypeptides and nucleic acids encoding the same - The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. | 08-06-2009 |
Nicholas F. Papatonis, Cuyahoga Falls, OH US
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20120313759 | Tracking system for persons and/or objects - An RFID-based tracking system that tracks persons and/or objects of interest without the need for triangulation techniques is disclosed. The system tracks persons and/or objects of interest by utilizing RFID antennas having a relatively small field of view and positioned relative to functional areas of a facility and/or within passageways between functional areas of the facility. The persons and/or objects of interest to be tracked are provided with an RFID tag. The present invention provides the system user with the ability to determine whether the persons and/or objects of interest are present within a particular functional area of the facility regardless of whether the presence of the person and/or object of interest is continuously detected by the system. | 12-13-2012 |
20140210617 | System to facilitate well-being checks - A system for checking the well-being of individuals within an institution is disclosed. The system is comprised of portable wireless devices in the possession of individual(s) who are to perform the well-being checks, a wireless communication network, and a computer device that is connected to the portable wireless devices by the wireless communication network. The computer device executes well-being software and is provided with well-being databases containing the well-being checks to be performed for each person, and has access to a tracking system. The tracking system determines the location of the person on whom such well-being checks are to be performed, the individual performing such well-being checks, and monitors and records whether such well-being checks have been performed. | 07-31-2014 |
Nicholas F. Reingold, Madison, NJ US
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20100217773 | METHOD FOR WEB-BASED EXPLORATION OF NETWORK INFRASTRUCTURE - In accordance with the teachings of the present invention, a method of data drilling is presented. A network database is deployed in a network, such as the Internet, for broad-based user access. Network information is stored in the network database and is organized in layers. A graphical user interface with data objects is presented to an end user. Selecting a data object generates a query performed by a server. Each query produces more details on an initially selected data object. | 08-26-2010 |
Nicholas F. Waggle, Jr., Derry, PA US
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20130224519 | Coating For Improved Wear Resistance - In one aspect, coated cutting tools are described herein which, in some embodiments, can demonstrate improved wear resistance in one or more cutting applications. In some embodiments, a coated cutting tool described herein comprises a substrate and a coating adhered to the substrate, the coating comprising an inner layer deposited by physical vapor deposition and an outer deposited by physical vapor deposition over the inner layer. | 08-29-2013 |