Nanna
Nanna Albaek, Birkerod DK
Patent application number | Description | Published |
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20150275212 | Oligonucleotide Conjugates - The invention relates to the field of oligonucleotide therapeutics, and in particular to the use of a cleavable, e.g. a phosphodiester region covalently attached to a conjugate, a targeting group or blocking group to enhance the properties of the oligonucleotides, for example to improve the therapeutic index. | 10-01-2015 |
20150291958 | ANTI APOB ANTISENSE CONJUGATE COMPOUNDS - The present invention relates to conjugates of LNA antisense oligonucleotides (oligomers) that target ApoB. | 10-15-2015 |
Nanna AlbÆk, Birkeroed DK
Patent application number | Description | Published |
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20150368642 | LNA OLIGONUCLEOTIDE CARBOHYDRATE CONJUGATES - The invention provides LNA therapeutics oligonucleotide carbohydrate conjugates with considerably enhanced potency, extended therapeutic index and reduced toxicity. | 12-24-2015 |
Nanna AlbÆk, Hørsholm DK
Patent application number | Description | Published |
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20160138025 | OLIGONUCLEOTIDE CONJUGATES - The present invention relates to oligomeric compounds and conjugates thereof that target Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) PCSK9 mRNA in a cell, leading to reduced expression of PCSK9. Reduction of PCSK9 expression is beneficial for a range of medical disorders, such as hypercholesterolemia and related disorders. | 05-19-2016 |