Patent application number | Description | Published |
20090011995 | PRODUCTION OF A SOLUBLE NATIVE FORM OF RECOMBINANT PROTEIN BY THE SIGNAL SEQUENCE AND SECRETIONAL ENHANCER - The present invention is drawn to a method for enhancing secretional efficiency of a heterologous protein using a secretional enhancer consisting of a modified signal sequence which comprises the N-region of a signal sequence and/or a hydrophobic fragment of the said signal sequence comprising the said N-region and/or the hydrophilic polypeptide. The method of the present invention can be used not only for production of recombinant heterologous proteins by inhibiting insoluble precipitation and enhancing secretional efficiency of the recombinant protein into the periplasm or the extracellular fluid and but also for transduction of therapeutic proteins by enhancing membrane-permeability of the recombinant protein using a strong secretional enhancer. | 01-08-2009 |
20100305040 | PRODUCTION OF SOLUBLE RECOMBINANT PROTEIN BY PI VALUE CONTROL OF N-TERMINAL - The present invention relates to a method for improving secretion efficiency of a recombinant foreign protein using a polypeptide fragment containing N-region of a signal sequence (directional signal) or variants thereof with the controlled pI value and/or a secretional enhancer composed of a hydrophilic polypeptide with the controlled pI value. The method of the present invention can be not only useful for the production of a recombinant foreign protein by preventing precipitation of an insoluble precipitate and by increasing extracellular or extra-periplasmic secretion efficiency of a recombinant protein but also useful for the transduction of an effective therapeutic protein by increasing membrane permeability using a strong secretional enhancer. | 12-02-2010 |
20130084602 | SOLUBLE EXPRESSION OF BULKY FOLDED ACTIVE PROTEINS - The present invention relates to expression vectors and methods for enhancing soluble expression and secretion of a heterologous protein, particularly a bulky folded active heterologous protein which has one or more transmembrane-like domains or intramolecular disulfide bonds by linking a leader peptide with acidic or basic pI and high hydrophilicity thereto; by substituting one or more amino acids within N-terminal of the heterologous protein with ones having acidic or neutral pI and high hydrophilicity; or reducing elevating G | 04-04-2013 |
20130302299 | NOVEL PROBIOTIC BACILLUS SP. STRAIN - The present invention relates to a novel | 11-14-2013 |
20140377801 | ARTIFICIAL SIGNAL PEPTIDE FOR EXPRESSING AN INSOLUBLE PROTEIN AS A SOLUBLE ACTIVE FORM - The present invention relates to expression vectors and methods for enhancing soluble expression and secretion of an insoluble heterologous protein, particularly a bulky folded active heterologous protein which has one or more transmembrane-like domains or intramolecular disulfide bonds by linking a leader peptide with acidic or basic pl and high hydrophilicity thereto; by substituting one or more amino acids within N-terminal of the heterologous protein with ones having acidic or neutral pl and high hydrophilicity; or reducing elevating ΔG | 12-25-2014 |
Patent application number | Description | Published |
20140322495 | INTERIOR FILM COMPRISING THREE-DIMENSIONAL PATTERN, AND METHOD FOR PREPARING SAME - The present invention relates to an interior film comprising a UV curable resin layer, a metal layer, and an adhesive layer, wherein a three-dimensional pattern is formed on the UV curable resin layer. More specifically, various forms of high quality metal texture can be expressed by forming a three-dimensional pattern on the UV curable resin layer, and the three-dimensional pattern can be clearly and sophisticatedly implemented without collapsing by further comprising a top coating layer. | 10-30-2014 |
20140335320 | HIGH GLOSS MOLDING SHEET HAVING METALLIC EFFECT USING ULTRAVIOLET CURABLE RESIN LAYER AND A METHOD FOR MANUFACTURING THE SAME - The present invention relates to a high glossy molding sheet and a method for manufacturing the same that may realize a same outer appearance with an actual metal surface by forming a reverse pattern with an opposite shape to an original pattern of a metal board using a transfer of an ultraviolet curable resin layer, and forming a metal deposition layer on the top and laminating on a board. | 11-13-2014 |
20150174949 | INTERIOR FILM HAVING TRANSVERSE HAIRLINES FORMED THEREIN AND A METHOD FOR MANUFACTURING THE INTERIOR FILM - The present invention provides an interior film having a transverse hairline implemented therein and, more specifically, provides an interior film (F) having a transverse hairline implemented therein, comprising: a transparent plastic film layer ( | 06-25-2015 |
Patent application number | Description | Published |
20090303252 | Registration Of CT Image Onto Ultrasound Images - Embodiments for registering a CT image onto ultrasound images are disclosed. At a preoperative stage, a plurality of first ultrasound images are formed during a respiratory cycle and a CT image is obtained at the maximum inspiration. The CT image is registered onto each of the ultrasound images to thereby form ultrasound-CT registered images. The ultrasound-CT registered images may be stored in the storage unit. Subsequently, at an intraoperative stage, a plurality of second ultrasound images may be sequentially formed in real time. Similarities may be measured between the first ultrasound images and the second ultrasound images, and the ultrasound-CT registered images, each corresponding to each of the first ultrasound images having highest similarity to the second ultrasound image may be retrieved. The retrieved ultrasound image and the second ultrasound image may be displayed at the same time. | 12-10-2009 |
20090304252 | Non-Rigid Registration Between CT Images And Ultrasound Images - There are disclosed embodiments for non-rigid image registration between 3-dimensional ultrasound and CT images by using intensity and gradient information of vessels and diaphragm. An ultrasound image forming unit transmits/receives ultrasound signals to/from a target object to thereby output electrical receive signals, and forms 3-dimensional ultrasound images based on the electrical receive signals. A CT image forming unit forms 3-dimensional CT images of the target object. A registration unit determines first and second objective functions associated with diaphragm and vessel regions of the target object, respectively, based on intensity and gradient information upon portions corresponding to the diaphragm and vessel regions in each of the 3-dimensional ultrasound and CT images. The registration unit performs non-rigid image registration between the 3-dimensional ultrasound images and the 3-dimensional CT images based on the first and second objective functions. | 12-10-2009 |
20090306507 | Anatomical Feature Extraction From An Ultrasound Liver Image - There is disclosed an embodiment for extracting anatomical features from a 3-dimensional B-mode ultrasound liver image for image registration. A system extracts anatomical features from a 3-dimensional B-mode ultrasound liver image for image registration. An image forming unit forms a 3-dimensional ultrasound liver image based on ultrasound signals reflected from the liver. A diaphragm extracting unit extracts a diaphragm region from the 3-dimensional B-mode ultrasound liver image. A vessel extracting unit extracts vessel regions from the 3-dimensional ultrasound liver image. A diaphragm refining unit refines the extracted diaphragm region with the extracted vessel regions to remove clutters from the diaphragm region. A registration unit extracts sample points from the diaphragm region with the clutters removed and the vessel regions for image registration. | 12-10-2009 |
20110026796 | SENSOR COORDINATE CALIBRATION IN AN ULTRASOUND SYSTEM - There is disclosed an embodiment for performing a calibration of a sensor by using an image registration between a three-dimensional ultrasound image and computerized tomography (CT) image. An ultrasound image forming unit includes an ultrasound probe and forms a three-dimensional ultrasound image of a target object. A sensor is coupled to the ultrasound probe. A memory stores a three-dimensional computed tomography (CT) image of the target object and position information on a position between the three-dimensional ultrasound image and the sensor. A processor performs image registration between the three-dimensional CT image and the three-dimensional ultrasound image to form a first transformation function for transforming a position of the sensor to a corresponding position on the three-dimensional CT image and performs calibration of the sensor by applying the position information to the first transformation function. | 02-03-2011 |
20110028843 | PROVIDING A 2-DIMENSIONAL CT IMAGE CORRESPONDING TO A 2-DIMENSIONAL ULTRASOUND IMAGE - There is disclosed a system and method for providing a 2-dimensional CT image corresponding to a 2-dimensional ultrasound image by performing an image registration between a 3-dimensional ultrasound image and a 3-dimensional CT image. The system comprises: a CT image forming unit configured to form a plurality of 3-dimensional CT images for an object of interest inside a target object; an ultrasound image forming unit configured to form at least one 3-dimensional ultrasound image for the object of interest; a processor configured to perform image registration between the 3-dimensional CT images and the at least one 3-dimensional ultrasound image to obtain a first transform function; and a user input unit configured to receive input information from a user, wherein the ultrasound image forming unit is further configured to form a 2-dimensional ultrasound image from the at least one 3-dimensional ultrasound image based on the input information, and wherein the processor is further configured to obtain a plurality of 2-dimensional CT images from the 3-dimensional CT images based on the input information and the first transform function and to detect similarities between the 2-dimensional ultrasound image and the 2-dimensional CT images to select one of the 2-dimensional CT images corresponding to the 2-dimensional ultrasound image. | 02-03-2011 |
20110028844 | SYSTEM AND METHOD FOR PROVIDING 2-DIMENSIONAL COMPUTERIZED-TOMOGRAPHY IMAGE CORRESPONDING TO 2-DIMENSIONAL ULTRASOUND IMAGE - Embodiments for providing a 2-dimensional (D) computerized-tomography (CT) image corresponding to a 2-D ultrasound image through image registration between 3-D ultrasound and CT images are disclosed. An imaging system comprises a CT imaging unit, an ultrasound image forming unit, a storing unit, a processor and a display unit. The processor extracts the 2-D CT image from the 3-D ultrasound-CT registered image by performing a rigid-body transform upon the 3-D ultrasound image and calculating similarities between reference images and the 2-D ultrasound images, wherein the reference images are obtained through the rigid-body transform. | 02-03-2011 |
20110268334 | Apparatus for Improving Image Resolution and Apparatus for Super-Resolution Photography Using Wobble Motion and Point Spread Function (PSF), in Positron Emission Tomography - Provided are an apparatus and method for improving image resolution in a positron emission tomography (PET), which may reconstruct a high-resolution image in a PET system using a motion of an entire detector or a bed motion and may maintain a characteristic of a sinograms using a positive number in a sinogram computing, by applying a super-resolution algorithm that may be based on a maximum likelihood expectation maximization (MLEM) algorithm. | 11-03-2011 |
20130101193 | Positron Emission Tomography and Method for Correcting Attenuation of PET Image Using Magnetic Resonance Image - A positron emission tomography (PET) image attenuation correction method may be provided. The PET image attenuation correction method may include obtaining n three-dimensional (3D) magnetic resonance (MR) images and n 3D PET images classified based on a breathing state of an examined patient, generating attenuation correction maps with respect to the n 3D MR images using a single computed tomography (CT) image, obtained in advance, associated with the patient, correcting attenuation of the n 3D PET images based on the generated attenuation correction maps, and generating a single PET image by combining the n attenuation-corrected 3D PET images. | 04-25-2013 |
20130231559 | SYSTEM AND METHOD FOR PROVIDING 2-DIMENSIONAL COMPUTERIZED- TOMOGRAPHY IMAGE CORRESPONDING TO 2-DIMENSIONAL ULTRASOUND IMAGE - Embodiments for providing a 2-dimensional (D) computerized-tomography (CT) image corresponding to a 2-D ultrasound image through image registration between 3-D ultrasound and CT images are disclosed. An imaging system comprises a CT imaging unit, an ultrasound image forming unit, a storing unit, a processor and a display unit. The processor extracts the 2-D CT image from the 3-D ultrasound-CT registered image by performing a rigid-body transform upon the 3-D ultrasound image and calculating similarities between reference images and the 2-D ultrasound images, wherein the reference images are obtained through the rigid-body transform. | 09-05-2013 |
20150289855 | SENSOR COORDINATE CALIBRATION IN AN ULTRASOUND SYSTEM - There is disclosed an embodiment for performing a calibration of a sensor by using an image registration between a three-dimensional ultrasound image and computerized tomography (CT) image. An ultrasound image forming unit includes an ultrasound probe and forms a three-dimensional ultrasound image of a target object. A sensor is coupled to the ultrasound probe. A memory stores a three-dimensional computed tomography (CT) image of the target object and position information on a position between the three-dimensional ultrasound image and the sensor. A processor performs image registration between the three-dimensional CT image and the three-dimensional ultrasound image to form a first transformation function for transforming a position of the sensor to a corresponding position on the three-dimensional CT image and performs calibration of the sensor by applying the position information to the first transformation function. | 10-15-2015 |
Patent application number | Description | Published |
20120056781 | APPARATUS AND METHOD FOR ULTRA-FAST GNSS INITIAL POSITIONING SCHEME WITH PEER ASSISTANCE, AND RECORDING MEDIUM THEREOF - A method and an apparatus for acquiring an ultra-fast global navigation satellite systems (GNSS) initial position with peer assistance are disclosed. The apparatus includes a communication unit configured to receive assistance generated using a distance from a master terminal to a slave terminal and frequency error of a counterpart's terminal, a communication signal system configured to immediately receive immediately necessary information of the assistance, a Global Positioning System (GPS) receiver configured to rapidly search for a GPS satellite signal using the assistance and continuously track the GPS satellite signal so as to extract a pseudorange, and a computation processor configured to compute the position of the slave terminal using the assistance and the pseudorange. By this configuration, it is possible to perform fast initial position measurement as compared to the existing A-GPS technique, achieve direct communication between two GPS receivers regardless of presence/absence of a mobile communication network, and solve various limitations of the A-GPS technique. | 03-08-2012 |
20120063491 | SPREAD SPECTRUM SIGNAL RECEIVER, METHOD FOR MULTIPATH SUPER-RESOLUTION THEREOF, AND RECORDING MEDIUM THEREOF - A spread-spectrum signal receiver, a multipath signal super-resolution method thereof, and a recording medium thereof are disclosed. Using a least-squares based iterative multipath super-resolution (LIMS) algorithm, the spread-spectrum signal receiver accurately resolves multipath signals in a multipath channel environment so as to extract necessary information such that a rake receiver tracks the multipath signals more accurately. Since the LIMS technique has high resistance against noise and require less computation, it may be used to resolve the multipath signals in real time and to extract a first arrival path signal of a first arrival signal and may be easily implemented offline. | 03-15-2012 |