Myung Hyun
Myung Hyun Jang, Seoul KR
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20140107023 | NON-PEPTIDYL POLYMER-INSULIN MULTIMER AND METHOD FOR PRODUCING THE SAME - The present invention relates to a non-peptidyl polymer-insulin multimer comprising two or more of a non-peptidyl polymer-insulin conjugate prepared by linking a non-peptidyl polymer and insulin via a covalent bond, in which the conjugates are complexed with cobalt ion to form a multimer, a method and kit for the preparation of the multimer, a pharmaceutical composition for the prevention or treatment of diabetes comprising the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to a subject. | 04-17-2014 |
20140120120 | COMPOSITION FOR TREATING DIABETES COMPRISING LONG-ACTING INSULIN CONJUGATE AND LONG-ACTING INSULINOTROPIC PEPTIDE CONJUGATE - The present invention relates to a composition for the prevention or treatment of diabetes comprising a long-acting insulin conjugate and a long-acting insulinotropic peptide conjugate, and a therapeutic method for the treatment of diabetes, and more particularly, concurrent administration of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate inhibits weight gain caused by insulin treatment, and vomiting and nausea caused by insulinotropic peptide treatment, and reduces the required dose of insulin, thereby remarkably improving drug compliance. Moreover, each of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate of the present invention is prepared by linking insulin or insulinotropic peptide with an immunoglobulin Fc region via a non-peptidyl linker, thereby showing improved in-vivo duration of efficacy and stability. | 05-01-2014 |
20140128318 | NOVEL OXYNTOMODULIN DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY COMPRISING THE SAME - The present invention relates to a novel peptide showing more excellent activities on a glucagon like peptide-1 receptor and a glucagon receptor than native oxyntomodulin, and a composition for the prevention or treatment of obesity comprising the peptide as an active ingredient. Unlike native oxyntomodulin, the novel peptide of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis with reduced side-effects, and also shows excellent receptor-activating effects. Thus, it can be widely used in the treatment of obesity with safety and efficacy. | 05-08-2014 |
20140296475 | METHOD FOR PREPARING PHYSIOLOGICALLY ACTIVE POLYPEPTIDE COMPLEX - A method for preparing a conjugate of a physiologically active polypeptide and a non-peptide polymer by linking physiologically active polypeptide with non-peptide polymer through a covalent bond using an organic solvent is provided. A method for preparing a physiologically active polypeptide complex by linking the conjugate with a carrier is provided. The complex shows improved in vivo duration and stability of the physiologically active polypeptide. The method can prepare the conjugate at a lower production cost, and the resulting conjugate shows an extension of in vivo activity at a relatively high level and significantly increase in the blood half-life. | 10-02-2014 |
Myung Hyun Lee, Daejeon KR
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20090304325 | OPTICAL WIRING MODULE - Provided is an optical wiring module. The optical wiring module includes a light source mounted on a surface of a substrate, a metal optical waveguide coupled to a transverse magnetic mode of light emitted from the light source and using a long-range surface palsmon polariton, and a photodetector. The optical wiring module has a simple structure enabling it to be further miniaturized and its yield to be increased. | 12-10-2009 |
Myung Hyun Lee, Seoul KR
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20140287424 | SLIDE CHIP FOR DETECTION SENSOR OF FOOD-BORNE PATHOGENS AND PREPARATION METHOD THEREOF - The present invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof. More particularly, the invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof, the slide chip comprising: a substrate coated with a metal; a linker having a substituent which may be bonded to the metal and is located at the 5′ end of deoxythymidine (dT); and a food-borne bacterium-derived RNA aptamer that is bound to the linker by the 3′-end poly A tail. The slide chip makes it possible to detect food-borne bacteria in a rapid and accurate manner. | 09-25-2014 |
20150093071 | SURFACE PLASMON POLARITON CIRCUIT ELEMENT WITH DISCONTINUOUS WAVEGUIDE WITH GAP AND APPARATUS AND METHOD FOR GENERATING SURFACE PLASMON POLARITON MODE - A plasmonic device and an apparatus and method for generating a surface plasmon polariton (SPP) mode using the plasmonic device are disclosed herein. The plasmonic device includes a first plasmonic waveguide and a second plasmonic waveguide. The first plasmonic waveguide is made of a strip-shaped metal material forming at least one pair of first metal-dielectric interfaces along with a dielectric layer, and extends from an input location to a gap start location. The second plasmonic waveguide is made of a strip-shaped metal material forming at least one pair of second metal-dielectric interfaces in planes identical to those of the at least one pair of first metal-dielectric interfaces of the first plasmonic waveguide, and extends from a gap end location, spaced apart from the gap start location by the length of a gap along the propagation direction of the SPP, to an SPP output location. | 04-02-2015 |
Myung-Hyun Jo, Incheon KR
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20150179939 | PHOTOTHERMAL CONVERSION FILM HAVING GOOD VISIBLE LIGHT PENETRABILITY, AND TRANSFER FILM FOR OLED USING SAME - Disclosed are a photothermal conversion film having good photothermal conversion effects and also good visible light penetrability, and a transfer film for an OLED using same. The photothermal conversion film according to the present invention comprises a base film and a photothermal conversion layer formed on the base film, wherein the photothermal conversion layer includes a tungsten oxide-based material and has visible light penetrability of 20% or greater. | 06-25-2015 |
Myung-Hyun Lee, Suwon-Si KR
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20090191111 | PREPARATION METHOD OF CALCIUM PHOSPHATE-BASED CERAMIC POWDER AND COMPACT THEREOF - Disclosed herein is a method of preparing a highly sinterable calcium phosphate-based ceramic powder and a compact thereof. The calcium phosphate-based ceramic powder and compact thereof according to the present invention are advantageous in that they are very biocompatible and economical because they are prepared using natural materials, have nano-sized particles, and are highly sinterable, and thus can be used for bone substitute materials. | 07-30-2009 |
Myung-Hyun Ryu, Daejeon KR
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20130280603 | METHOD OF MANUFACTURING ANODE ACTIVE MATERIAL, AND ANODE AND LITHIUM BATTERY USING THE ANODE ACTIVE MATERIAL - Disclosed is to a method of manufacturing an anode active material, including mixing a first solution having a metal oxide precursor dissolved therein, a second solution having a polymer as a carbon fiber precursor dissolved therein, and an ionic liquid solution for nitrogen doping and formation of a porous structure, thus preparing an electrospinning solution, electrospinning the electrospinning solution, thus preparing a metal oxide-nitrogen-porous carbon nanofiber composite, and thermally treating the composite, and to an anode and a lithium battery using the anode active material. | 10-24-2013 |