Mortier
Erwan Mortier, Nantes Cedex 01 FR
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20160130318 | Interleukin 15 (IL-15) Antagonists and Uses Thereof for the Treatment of Autoimmune Diseases and Inflammatory Diseases - The present relates to interleukin 15 (IL-15) antagonists and uses thereof, in particular for the treatment of autoimmune diseases and inflammatory diseases. In particular, the present invention relates to an IL-15 mutant polypeptide having the amino acid sequence as set forth in SEQ ID NO:1 wherein the leucine residue at position 45 is substituted by an aspartic acid residue, the asparagines residue at position 65 is substituted by a lysine residue and the leucine residue at position 69 is substituted by an arginine residue | 05-12-2016 |
Erwan Mortier, Nantes FR
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20080255039 | Il-15 Binding Site for Il 15-Ralpha and Specific Il-15 Mutants Having Agonists/Antagonists Activity - The present invention relates to the identification of an epitope in human Interleukin-15 (IL-15) that is responsible for binding to the interleukin-15 receptor α-chain. Two IL-15 regions are involved in the formation of this epitope: the first region ( | 10-16-2008 |
20090238791 | IL-15RALPHA SUSHI DOMAIN AS A SELECTIVE AND POTENT ENHANCER OF IL-15 ACTION THROUGH IL-15BETA/GAMMA, AND HYPERAGONIST (IL-15RALPHA SUSHI - IL-15) FUSION PROTEINS - The present invention relates to the stimulation of the IL-15R beta/gamma signalling pathway, to thereby induce and/or stimulate the activation and/or proliferation of IL-15Rbeta/gamma-positive cells, such as NK and/or T cells. Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha. | 09-24-2009 |
20110158938 | IL-15 BINDING SITE FOR IL 15-RALPHA AND SPECIFIC IL-15 MUTANTS HAVING AGONISTS / ANTAGONISTS ACTIVITY - The present invention relates to the identification of an epitope in human Interleukin-15 (IL-15) that is responsible for binding to the interleukin-15 receptor α-chain. Two IL-15 regions are involved in the formation of this epitope: the first region ( | 06-30-2011 |
Geert P. Mortier, Gent BE
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20100011728 | Extendable header for harvesting machine - A header for a harvesting machine having a frame, a cutterbar mounted on the frame operable to cut standing crop, the cutterbar being adjustable relative to the frame in a fore-and-aft direction, and a reel rotatably supported between a pair of reel arms pivotally mounted on the frame and operable to sweep crop material towards and over the cutterbar, a hydraulic cylinder extending between each reel arm and a corresponding side wall of said header frame to effect a generally vertical movement of said reel, comprising an interlock mechanism operably interconnecting the cutterbar and the hydraulic cylinder at each side of the header for adjusting the vertical position of the reel in response to a fore-and-aft movement of the cutterbar to maintain substantially constant the spacing and avoiding interference between the reel and the cutterbar. | 01-21-2010 |
20100018176 | Belt drive for a harvesting header with a movable cutterbar - A header for a harvesting machine with a movable cutterbar includes a belt drive mechanism connecting a stationary pulley mounted on the frame of the header and a relatively movable pulley mounted on the movable part of the header. The belt drive mechanism includes two guide pulleys, a belt mounted along said pulleys and a pivot assembly mounted on the auger shaft. The guide pulleys a are mounted on opposite lever arms of the pivot and said belt drive mechanism further includes a tensioning mechanism. | 01-28-2010 |
20110232251 | CUTTERBAR SUPPORT FOR A CROP HARVESTING HEADER - A system for supporting a cutterbar of a crop harvesting header includes an adjustment assembly including a first arm pivotably secured to the header. The first arm includes a first portion configured to support the cutterbar, and a second portion including a torsion device having a mass of elastic material connected to the adjustment assembly. The second portion is configured to be pivotably rotatable about a first axis by the adjustment assembly to selectably increase or decrease a force appliable to the first portion in order to raise or lower the first portion with respect to the header. The system further includes a connecting lever having one end pivotally connected to an interconnecting member and another end coupled to the second arm, wherein the connecting lever has a pivot portion for rotation about a second axis the second axis is perpendicular to the first axis. | 09-29-2011 |
Jacques Mortier, Ecommoy FR
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20100331398 | DERIVES DU GOSSYPOL ET DE L'APOGOSSYPOL, LEURS PREPARATIONS ET LEURS APPLICTIONS - Gossypol and apogossypol derivatives of general formula (1), preparation thereof and use thereof. | 12-30-2010 |
20120316337 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP - Method for preparing carboxylic acid derivatives by aromatic nucleophilic substitution, in which a carboxylic acid derivative having a single carboxyl functional group, or one of the salts thereof, the carboxylic acid derivative having, in the ortho position of the carboxyl functional group, a leaving group, which is preferably an atom of fluorine or of chlorine or an alkoxy group, chiral or not, preferably a methoxy group, the carboxylic acid derivative not being substituted by an electro attractive group other than the leaving group if any; is reacted with a reactant MNu, where M is a metal and Nu is a nucleophile, chiral or not, the aromatic nucleophilic substitution reaction being carried out without a catalyst and without a step of protecting/deprotecting the acid functional group of the starting compound. | 12-13-2012 |
20120330056 | PROCESS FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP - A method for preparing aromatic carboxylic acid derivatives by nucleophilic aromatic substitution, involves reacting an aromatic carboxylic acid derivative supporting only one carboxyl function, or one of the salts thereof, the carboxylic acid derivative supporting, orthogonally to the carboxyl function, a leaving group which is a fluorine or chlorine atom or an alkoxy group, chiral or otherwise and, in the latter case, preferably a methoxy group; the carboxylic acid derivative being substituted by at least one electro-attractive group other than the leaving group, preferably by a fluorine atom, with a MNu reagent, wherein M is a metal and Nu an optionally chiral nucleophile, the nucleophilic aromatic substitution reaction being carried out without a catalyst and without a step of protecting/unprotecting the acid function of the initial compound, the method being selective in that the reaction leads to the formation of ketone derivatives in a very minority fashion during the reaction. | 12-27-2012 |
Katherine Mortier, Gent BE
Katherine An Hilde Mortier, Gent BE
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20150133523 | METHOD FOR DOWN-REGULATING GENE EXPRESSION IN FUNGI - The present invention concerns methods for controlling fungus infestation via dsRNA mediated gene silencing, whereby the intact fungus cell(s) are contacted with a double-stranded RNA from outside the fungal cell(s) and whereby the double-stranded RNA is taken up by the intact fungal cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from fungus pests. Alternatively, the methods are used for treating and/or preventing fungal infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable fungal target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed. | 05-14-2015 |
Peter Mortier, Anzegem BE
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20150112659 | PRE-OPERATIVE SIMULATION OF TRANS-CATHETER VALVE IMPLANTATION - In a first aspect, the present invention relates to a method for patient-specific virtual percutaneous implantation, comprising estimating a patient-specific anatomical model of a patient-specific aorta based on cardiovascular 2D or 3D medical image data and virtually deploying an implant model representing an implant into said patient-specific anatomical model. In a second aspect, the present invention provides a method for patient-specific virtual percutaneous implantation. In a third aspect, the present invention provides an implant for virtual percutaneous implantation. In a fourth aspect, the present invention provides a system for virtual percutaneous implantation. | 04-23-2015 |
Peter Mortier, Hulst NL
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20140244944 | WAIT-FREE ALGORITHM FOR INTER-CORE, INTER-PROCESS, OR INTER-TASK COMMUNICATION - A method and system are presented for providing deterministic inter-core, inter-process, and inter-thread communication between a reader and a writer. The reader and writer communicate by passing data through a shared memory using double buffering of double buffers. The shared memory includes a first double buffer and a second double buffer. Both double buffers include a first low level buffer and a second low level buffer. Using double buffering of the double buffers, both the reader and the writer may simultaneously access the shared memory. | 08-28-2014 |
20160004478 | WAIT-FREE ALGORITHM FOR INTER-CORE, INTER-PROCESS, OR INTER-TASK COMMUNICATION - A method and system are presented for providing deterministic inter-core, inter-process, and inter-thread communication between a reader and a writer. The reader and writer communicate by passing data through a shared memory using double buffering of double buffers. The shared memory includes a first double buffer and a second double buffer. Both double buffers include a first low level buffer and a second low level buffer. Using double buffering of the double buffers, both the reader and the writer may simultaneously access the shared memory. | 01-07-2016 |
Richard M. Mortier, Cambridge GB
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20120063323 | DISTRIBUTED NETWORK MANAGEMENT - Hosts or end-systems residing at the edges of a network gather data about the traffic they transmit into and receive from the network. The network's routing protocol (typically a link-state protocol such as OSPF) is monitored and routing data or packets are used to recover the network's current status and topology. This data can be collected, fused, and maintained and a platform, preferably distributed, can be provided to query the data, thus enabling a variety of network management applications. | 03-15-2012 |
Wilfried J. Mortier, Kessel-Lo BE
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20100028679 | Crystalline Intergrowth Material, Its Synthesis And Its Use In The Conversion Of Oxygenates To Olefins - A silicoaluminophosphate molecular sieve is disclosed that comprises first and second intergrown phases of a CHA framework type and an AEI framework type, wherein said first intergrown phase has an AEI/CHA ratio of from about 5/95 to about 40/60 as determined by DIFFaX analysis, the second intergrown phase has an AEI/CHA ratio of about 30/70 to about as determined by DIFFaX analysis and said molecular sieve has a silica to alumina molar ratio (Si/Al | 02-04-2010 |
20130317272 | Manganese Oxides and Their Use in the Oxidation of Alkanes - Catalytic structures are provided comprising octahedral tunnel lattice manganese oxides ion-exchanged with metal cations or mixtures thereof. The structures are useful as catalysts for the oxidation of alkanes and may be prepared by treating layered manganese oxide under highly acidic conditions, optionally drying the treated product, and subjecting it to ion exchange. | 11-28-2013 |
20150298982 | MFI With Unusual Morphology - A method of making a crystalline molecular sieve of MFI framework type, preferably ZSM-5, from a synthesis mixture comprising at least one source of tetravalent element (Y), at least one source of trivalent element (X), at least one source of alkali metal hydroxide (MOH), at least one structure directing agent (R) and water, said synthesis mixture having the following molar composition: YO | 10-22-2015 |
Wilfried Jozef Mortier, Kessel-Lo BE
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20150298982 | MFI With Unusual Morphology - A method of making a crystalline molecular sieve of MFI framework type, preferably ZSM-5, from a synthesis mixture comprising at least one source of tetravalent element (Y), at least one source of trivalent element (X), at least one source of alkali metal hydroxide (MOH), at least one structure directing agent (R) and water, said synthesis mixture having the following molar composition: YO | 10-22-2015 |