Monika
Monika Albinger, Biberach DE
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20080265734 | Refrigerator Unit and/or a Freezer Unit - The present invention relates to a refrigerator unit and/or a freezer unit having one or more storage shelves for the reception of refrigerated goods and/or frozen goods, wherein the appliance has one or more extension arrangements which are connected to the storage shelves and by means of which the storage shelves can be pulled out of and pushed into the appliance, wherein the extension arrangements are releasably connected to the storage shelves and/or wherein the extension arrangements are releasably connected to the appliance. | 10-30-2008 |
Monika Barathova, Bratislava SK
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20100056611 | MN/CA9 Splice Variants - Herein disclosed is an alternatively-spliced [AS] variant of MN/CA9 mRNA and its related protein—AS MN/CA IX. Unlike the tumor-associated, full-length [FL] MN/CA9 mRNA and FL MN/CA IX, which in most tissues signify oncogenesis and/or hypoxia, the AS MN/CA9 mRNA is constitutively-expressed under normoxia and is not stimulated by hypoxia, and the AS MN/CA IX is not confined to the cell membrane. Provided herein are diagnostic/prognostic methods for preneoplastic/neoplastic disease to differentiate between AS and FL MN/CA9 expression, and probes, primers, and antibodies useful in such methods. Also disclosed are methods to treat pre-neoplastic/neoplastic disease involving the MN gene and protein, which methods are based on the ability of AS MN protein (AS MN/CA IX) to interfere with the catalytic activity of FL MN protein (FL MN/CA IX); such methods may also use AS MN protein fragments that have that interference capability. Such methods may comprise increasing the levels of AS MN/CA IX relative to the levels of FL MN/CA IX. Exemplary therapeutic methods may comprise the administration of agents, such as, AS MN/CA IX itself, a vector expressing AS MN/CA9 mRNA, an antisense oligonucleotide that blocks expression of FL MN/CA IX but not that of AS MN/CA IX, a vector expressing such an antisense oligonucleotide, a FL MN/CA9 isoform-specific siRNA, or a vector expressing such FL MN/CA9 isoform-specific siRNA. Further disclosed are methods to identify agents capable of modulating levels of AS MN/CA IX. | 03-04-2010 |
Monika Barbenheim, Bottrop DE
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20110014148 | Cationic Surfactants Having Improved Properties - The invention is directed to cationic surfactants of formula (I), where R1 is a saturated or unsaturated, branched or linear alkyl group having 6 to 22 carbon atoms, R2 and R3 independently are C1-C3 alkyl groups or hydrogen, n is 2 or 3, and X | 01-20-2011 |
20130251661 | SOFTENER FOR TEXTILES - What are described are textile treatment compositions comprising hydroxylated lecithin, at least one dispersant, preferably an alkyl(oligo)glycoside, at least one wax and water, and optionally further assistants and additives. | 09-26-2013 |
20150071867 | Hair Cosmetic Composition Which Comprises A Plant Lecithin - Described is a hair cosmetic composition which comprises at least one plant lecithin, at least one anionic surfactant, and at least one fatty alcohol. | 03-12-2015 |
Monika Baudler, Konstanz DE
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20080242681 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors - Compounds of a certain formula 1 in which R1 and R2 have the meanings indicated in the description are novel kinase inhibitors. Formula (1), in which R1 is phenyl, phenyl substituted by R3 and/or R4, naphthalenyl, naphthalenyl substituted by and/or R6, aryl1, aryl1 substituted by R7 and/or R8, R9, R10 or R11, R2 is phenyl, phenyl substituted by R12 and/or R13, naphthalenyl, naphthalenyl substituted by R14 and/or R15, aryl2, aryl2 substituted by R16 and/or R17 or a radical selected from Formula (2). | 10-02-2008 |
20090170125 | Cellular assay method for identifying pkc-0 inhibitors - The invention relates to a method for investigating the modulating effect of a test substance on a PKCθ-dependent signal transduction pathway or for finding a PKCθ modulator in a human or animal cell, including the steps | 07-02-2009 |
Monika Bauer, Senzig DE
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20090054540 | Cyanate-Based, Carbon-Dioxide-Filled Structured Foams and Method for Their Production - The present invention concerns a polycyanurate foam with a structural element A and either terminal amino groups and/or at least one of the following structural elements B, C, or D: | 02-26-2009 |
20100195025 | Display Cell with Compartmentalized Liquid-Crystal Layer, Method for its Production and a Liquid-Crystal Material-Containing Mixture Suitable Therefor - The invention relates to a display cell, comprising two transparent, equidistant plates, wherein the gap between the plates is filled with a liquid-crystal material-containing layer, characterized in that the liquid-crystal material-containing layer is inhomogeneous and anisotropic, wherein it has a first region made up of compartments, which comprise entirely, substantially or mainly liquid-crystal material, and a second, coherent region which comprises entirely, substantially or mainly an organic polymer material and surrounds the compartments made of liquid-crystal material. In addition, the invention relates to a liquid-crystal material-containing mixture which can be used to produce the layer between the plates, and to a method for producing the display cell. | 08-05-2010 |
Monika Bauer, Koenigs Wusterhausen DE
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20100112338 | Polymer film for surface coating fiber/plastics composite materials - The use of a substrate supported polymer film as a surface coating for fiber/plastics composite structures produced by the crushed core method from composite structures having a core and at least one prepreg layer, wherein the polymer film is applied to a prepreg surface with its resin side facing the surface before the composite structure is cured and optionally before it is placed in the mold, and curing is effected under applied pressure and at an elevated temperature. The substrate supported polymer film comprises a resin matrix which has a degree of crosslinking that is below its gel point, and which is produced from at least one difunctional or polyfunctional aromatic organic cyanate and at least one difunctional or polyfunctional aromatic alcohol in proportions giving a molar ratio of OCN groups to OH groups in the starting materials used for the production of the prepolymer of from 95:5 to 70:30, and which also contains at least one filler. | 05-06-2010 |
20120082850 | ORGANICALLY FUNCTIONALIZED POLYSILOXANE NANOPARTICLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF - The present invention relates to polysiloxane nanoparticles have the following properties: an average particle size d | 04-05-2012 |
20120114952 | ADHESIVE COMPOSITION FOR DETACHABLE ADHESIVE BONDS AND MODIFICATION OF THE ENCAPSULATION MATERIALS FOR A PURPOSEFUL ENERGY INPUT - An adhesive composition for detachable adhesive bonds is based on adhesive matrices and expansion material, the particles of the expansion material being at least partially encapsulated. | 05-10-2012 |
20120248641 | ACRYLONITRILE-SILAZANE COPOLYMERS, ESPECIALLY IN FIBER FORM, PROCESS FOR PREPARATION THEREOF AND USE THEREOF - The present invention pertains to a copolymer obtained by reacting a mixture of acrylonitrile or of a mixture of acrylonitrile and an organic molecule that can be copolymerized with acrylonitrile, with which a monomeric, oligomeric and/or polymeric silazane can be obtained, said silazane containing at least one vinylic double bond. The copolymer can be brought into fiber form and/or made infusible. The production of ceramic fibers by pyrolysis is possible with fiber-like copolymers. | 10-04-2012 |
20130196143 | ADHESIVE COMPOSITION FOR DETACHABLE ADHESIVE BONDS AND MODIFICATION OF THE ENCAPSULATION MATERIALS FOR A PURPOSEFUL ENERGY INPUT - An adhesive composition for detachable adhesive bonds is based on adhesive matrices and expansion material. The particles of the expansion material are at least partially encapsulated. A bond of at least two components and an adhesive layer includes an adhesive composition based on adhesive matrices and expansion material. The bonded components may include metal, plastic, wood, glass, natural or synthetic materials or a composite material thereof. | 08-01-2013 |
20140199906 | CYANATE-BASED RESINS WITH REDUCED VISCOSITY AND DUROMERS PRODUCED THEREFROM WITH IMPROVED IMPACT RESISTANCE - The invention relates to a cyanate resin that can be obtained by mixing at least | 07-17-2014 |
20140234632 | WOOD SUBSTRATE FURNISHED WITH A FLAME RETARDANT - The invention relates to a wood substrate rendered flame-retardant. The invention provides that on the substrate there is a coating and/or impregnation system with a flame retardant selected from the group consisting of room-temperature-liquid organic halogen compounds and organic phosphorus compounds and organic boron compounds, and that there is also a layer of coating material applied thereto. | 08-21-2014 |
20140275373 | POLYSILOXANE MODIFIED RESOL RESIN, MOULDED BODIES AND COMPOSITES OBTAINED THEREFROM AND METHODS FOR PRODUCING THE RESIN, THE MOULDED BODIES AND THE COMPOSITES - The present invention relates to a resol resin consisting of at least one aromatic component with a phenolic OH group and at least one aldehyde component, wherein areas embedded in the resol resin matrix consisting of organically-modified polysiloxane, with said polysiloxane containing hydrocarbon groups that are at least partially bonded to said silicon in the form of non-substituted or substituted alkyl, alkenyl, aryl, arylalkyl or alkyl-aryl groups and that are not linked by covalent bonds to reactive groups of said resol resin. The invention additionally relates to moulded articles manufactured from said resin, composites from a sheet material impregnated with said resin, which was subsequently hardened, as well as methods for manufacturing said resin, said moulded articles, and said composites. | 09-18-2014 |
Monika Berweiler, Maintal DE
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20080214387 | Process For Modifying Catalysts and the Use of the Catalysts - Process for modifying catalysts via the deposition of carbon containing residues in the presence of one or more solvents, where the gas phase over the catalyst treatment solution during the treatment is air or an inert gas, and/or the liquid phase contains a templating agent and/or base. The modified catalyst can be used for stereo-, chemo- and regioselective transformations of organic compounds. | 09-04-2008 |
20090018366 | PRODUCTION AND USE OF SUPPORTED ACTIVATED BASE METAL CATALYSTS FOR ORGANIC TRANSFORMATION - Method for the production of supported activated metal catalysts, whereby an alloy, a metal powder, a pore builder is dispersed in a water, the dispersion is sprayed on a support which is the dried, calcined and activated. The catalysts can be used for organic transformations, i.e. for hydrogenation reactions. | 01-15-2009 |
20090264679 | Control of metal catalyst settling rates, settling densities and improved performance via use of flocculants - A process for the adjustment of a catalyst's or a catalyst precursor's suspension and settling properties, whereby the catalyst is treated with flocculants. | 10-22-2009 |
20100174116 | Activated Base Metal Catalysts - Nitro-compounds are hydrogenated with an activated Ni catalyst that is doped during and/or after activation with one or more elements from the list of Mg, Ca, Ba, Ti, Zr, Ce, Nb, Cr, Mo, W, Mn, Re, Fe, Co, Ir, Ni, Cu, Ag, Au, Rh, Ru and Bi whereas the Ni/Al alloy may not, but preferentially can contain prior to activation one or more doping elements from the list of Ti, Ce, V, Cr, Mo, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Pd, Pt and Bi. If the Ni/Al alloy contained one or more of the above mentioned suitable alloy doping elements prior to activation, the resulting catalyst can then be doped with one or more of the elements from the list of Mg, Ca, Ba, Ti, Zr, Ce, V, Nb, Cr, Mo, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag, Au and Bi by their adsorption onto the surface of the catalyst. | 07-08-2010 |
20100185026 | Activated Base Metal Catalysts - Nitro-compounds are hydrogenated with an activated Ni catalyst whose Ni/Al alloy also contained one or more elements from the list of Cu, Ag and Au prior to activation. In combination with the Group IB elements mentioned above, this catalyst can also be doped with other elements via their addition to the Ni/Al alloy prior to activation and/or they can be adsorbed onto the surface of the catalyst either during or after the activation of the alloy. The suitable doping elements for the alloy prior to activation in combination with the group IB elements mentioned above are one or more of the elements from the list of Mg, Ti, Ce, Cr, V, Mo, W, Mn, Re, Fe, Co, Tr, Ru, Rh, Pd, Pt and Bi. The suitable doping elements that may be adsorbed onto the surface of the catalyst that was previously doped in the alloy prior to activation with the group IB elements mentioned above are one or more elements from the list Mg, Ca, Ba, Ti, Ce, V, Cr, Mo, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Pd, Pt, Ni, Cu, Ag, Au and Bi. | 07-22-2010 |
20100204517 | Activated Base Metal Catalysts - Nitro-compounds are hydrogenated with an activated Ni catalyst that has an average particle size (APS) less than 25 μm and is doped with one or more elements from the list of Mg, Ce, Ti, V, Nb, Cr, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Pt, Cu, Ag, Au and Bi via its/their addition to the alloy before activation and/or doped with one or more elements from the list of Mg, Ce, Ti, V, Nb, Cr, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Ni, Cu, Ag, Au and Bi by their adsorption onto the surface of the activated catalyst. This invention also includes the hydrogenation of nitro-compounds with an activated Ni catalyst that has and APS less than 20 μm and is doped with one or more elements from the list of Mg, Ce, Ti, V, Nb, Cr, W, Mn, Re, Fe, Ru, Co, Rh, Tr, Pt, Pd, Mo, Cu, Ag, Au and Bi via its/their addition to the alloy before activation and/or doped with one or more elements from the list of Mg, Ce, Ti, V, Nb, Cr, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Ni, Cu, Pd, Pt, Mo, Ag, Au and Bi by their adsorption onto the surface of the activated catalyst. | 08-12-2010 |
20110218362 | Fixed Bed Hydrogenation Of Fatty Nitriles To Fatty Amines - A process for the fixed bed hydrogenation of unsaturated fatty nitriles to fatty amines with a fixed bed Raney-type Ni/Al, Co/Al or Ni/Co/Al catalyst in the liquid phase, the trickle phase or any type of fatty nitrile aerosol. | 09-08-2011 |
Monika Blendel, Bad Soden DE
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20090101453 | Electromechanical Zero Backlash Brake - The invention relates to an electromechanical brake ( | 04-23-2009 |
Monika Bogiel, Pruszkow PL
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20110136736 | NEW INSULIN ANALOGUES OF PROLONGED ACTIVITY - New biosynthetic analogues of recombined human insulin of prolonged therapeutical activity, which can find place in prophylactic and treatment of diabetes. | 06-09-2011 |
20140121353 | INSULIN ANALOGUES OF PROLONGED ACTIVITY - New biosynthetic analogues of recombined human insulin of prolonged therapeutical activity, which can find place in prophylactic and treatment of diabetes. | 05-01-2014 |
Monika Borczyk, Bielsko-Biala PL
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20100273124 | STEADY PRESSURE DENTAL IMPRESSION TRAY AND THE IDEA OF OPERATION - An object making its impression in soft material, due to the force application, of various strength and impact directions, reproduces its parts at different heights, thus providing a distorted cast of the object. | 10-28-2010 |
Monika Casaretto, Mönchengladback DE
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20100029911 | Method For Solid-Phase Peptide Synthesis And Purification - Use of an activated solid phase and a peptide-conjugated anchoring part for solid phase peptide synthesis, wherein the anchoring part is coordinatively and reversibly attached to the activated solid phase. | 02-04-2010 |
Monika Casaretto, Mönchengladback DE
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20100029911 | Method For Solid-Phase Peptide Synthesis And Purification - Use of an activated solid phase and a peptide-conjugated anchoring part for solid phase peptide synthesis, wherein the anchoring part is coordinatively and reversibly attached to the activated solid phase. | 02-04-2010 |
Monika Dabroska, Edmonton CA
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20100145016 | COMPOSITIONS AND METHODS FOR PURIFYING CALRETICULIN - The present invention relates to compositions, methods for expressing, and related methods for purifying calreticulin that is free of an affinity label or tag (i.e., non-tagged calreticulin). The invention provides useful methods for commercial production of human calreticulin in a bacterial expression system such as | 06-10-2010 |
Monika Drews, Tallinn EE
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20110143432 | USE OF EXTRACT OF SELENIUM-ENRICHED YEAST (SE-YE) IN MAMMALIAN CELL CULTURE MEDIA FORMULATIONS - The invention relates to the use of extract of selenium-enriched yeast (Se-YE) as a supplement to the serum-free cell culture media formulations. The cell culture media comprising this supplement are particularly suitable for cultivating mammalian cells and for production of recombinant proteins and monoclonal antibodies. | 06-16-2011 |
Monika Eccard, Kernen DE
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20100268160 | DISPOSABLE SYRINGE WITH PROTECTION AGAINST REUSE - A disposable syringe with protection against reuse is proved. The syringe includes a cylinder with an injection nozzle and a piston that has a piston section facing the injection nozzle, a piston rod and an actuation section facing away from the piston section, wherein the piston rod has a latching section with a shoulder that is provided in or on the piston rod and runs radially inward, the cylinder has a counter-latching section protruding inward, and the piston has at least one predetermined breaking point in such a way that when the piston rod is introduced into the cylinder the counter-latching section engages behind the shoulder to lock it and counteracts removal the piston rod from the cylinder, and wherein the predetermined breaking point is designed such that it breaks when pulling on the actuation section. | 10-21-2010 |
Monika Ermann, Wantage GB
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20100076029 | Compounds Which Selectively Modulate The CB2 Receptor - Compounds of formula (I) | 03-25-2010 |
20100081644 | Compounds Which Selectively Modulate The CB2 Receptor - Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain. | 04-01-2010 |
20100261708 | Diazepane Compounds Which Modulate The CB2 Receptor - Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain. | 10-14-2010 |
20110071127 | Compounds Which Modulate the CB2 Receptor - Compounds of formula (I) | 03-24-2011 |
20110071196 | Compounds Which Selectively Modulate The CB2 Receptor - Compounds of formula (I) | 03-24-2011 |
20110130431 | Compounds Which Modulate The CB2 Receptor - Compounds of formula (I) | 06-02-2011 |
20110136869 | Compounds Which Selectively Modulate The CB2 Receptor - Compounds of formula (I) | 06-09-2011 |
20110190256 | Amine and Ether Compounds Which Modulate The CB2 Receptor - Compounds which modulate the CB2 receptor are disclosed. The compounds are useful for treating CB2 receptor-mediated diseases such as pain. | 08-04-2011 |
20110312932 | Therapeutic Uses of Compounds Which Selectively Modulate The CB2 Receptor - Compounds of formula (I) | 12-22-2011 |
20120010184 | Therapeutic Uses of Compounds Which Selectively Modulate The CB2 Receptor - Compounds of formula (I) | 01-12-2012 |
20120015988 | Sulfone Compounds Which Modulate The CB2 Receptor - Compounds which modulate the CB2 receptor are disclosed. Compounds according to the invention bind to and are agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain. | 01-19-2012 |
20120071529 | Tetrazole Compounds Which Selectively Modulate The CB2 Receptor - Compounds of formula (I) | 03-22-2012 |
20120316173 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR - Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain. | 12-13-2012 |
20130184315 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR - Compounds of formula (I) and formula (II) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain. | 07-18-2013 |
Monika Fellermeier, Munich DE
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20080311181 | Serum-Stable Amphoteric Liposomes - The invention relates to amphoteric liposomal formulations which are provided with great serum stability and are suitable for the intracellular delivery of oligonucleotides. | 12-18-2008 |
Monika Fellermeier, Griesstatt DE
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20090199313 | Non-mevalonate isoprenoid pathway - The present invention is directed to enzymes and intermediates of the non-mevalonate isoprenoid pathway downstream of 2C-methyl-D-erythritol 2,4-cyclopyrophosphate and upstream of isopentenyl pyrophosphate or dimethylallyl pyrophosphate. These are used as a basis for a screening method for inhibitors of these enzymes, and a method for identifying inhibitor-resistant variants thereof. Further disclosures refer to DNA coding for said enzymes and for inhibitor-resistant variants thereof, vectors containing said DNA, cells containing said vector, and plant seeds comprising cells containing said vector. This invention is useful for the inhibition of the biosynthesis of isoprenoids in plants, bacteria and protozoa, for conferring herbicide-resistance to plants, as well as for weed control in agriculture using a crop containing a herbicide-resistant gene and an effective amount of a suitable herbicide. | 08-06-2009 |
Monika Giesselbach, Koln DE
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20100324193 | A PROCESS FOR THE PRODUCTION OF NANODISPERSIBLE BOEHMITE AND THE USE THEREOF IN FLAME RETARDANT SYNTHETIC RESINS - The present invention relates to processes for the production of at least partially pepetizable and at least partially peptized boehmite particles, the at least partially pepetizable and at least partially peptized boehmite particles, and the use of the at least partially peptized boehmite particles to flame retard synthetic resins. | 12-23-2010 |
Monika Giesselbach, Koeln DE
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20110213065 | SYNTHETIC INORGANIC FLAME RETARDANTS, METHODS FOR THEIR PREPARATION, AND THEIR USE AS FLAME RETARDANTS - Quite unexpectedly, by suitably modifying the crystal structure of hydrogarnets of the general formula M | 09-01-2011 |
Monika Gorkani, San Jose, CA US
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20080319980 | METHODS AND SYSTEM FOR INTELLIGENT NAVIGATION AND CACHING FOR LINKED ENVIRONMENTS - A real-time, content-based document navigation and caching tool for use within linked-document environments. The system includes a combination of rooted spidering, ranking and displaying to provide the user with a capability to perform intelligent navigation of the document collection. The system allows users to intelligently browse their local information environments, finding the documents that are most relevant to their information needs but also respecting the locality of the user's current location within the hyperlinked environment. | 12-25-2008 |
Monika Hamers-Schneider, Freudenberg DE
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20110172420 | SULFONAMIDE DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS - The invention concerns the production of quinoline compounds containing sulfonic acid groups, the said quinoline compounds and their conversion into dyes containing sulfonic acid groups. The dyes according to the invention are used especially to label analytes, for example to label biomolecules. | 07-14-2011 |
20110190486 | SULFONAMIDE DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS - The invention concerns the production of quinoline compounds containing sulfonic acid groups, the said quinoline compounds and their conversion into dyes containing sulfonic acid groups. The dyes according to the invention are used especially to label analytes, for example to label biomolecules. | 08-04-2011 |
20110223677 | CARBOXAMIDE-SUBSTITUTED DYES FOR ANALYTICAL APPLICATIONS - The present invention relates to carboxamide-substituted dyes, the production and use of such dyes as labeling groups in analytics. | 09-15-2011 |
20130224871 | Novel Amine-Substituted Tricyclic Fluorescent Dyes - The present invention relates to polycyclic compounds of the general formula (I) which are distinguished by an amine substituent NR | 08-29-2013 |
20130323851 | CARBOXAMIDE-SUBSTITUTED DYES FOR ANALYTICAL APPLICATIONS - The present invention relates to carboxamide-substituted dyes, the production and use of such dyes as labeling groups in analytics. | 12-05-2013 |
Monika Hasbach Lugo, Col Toriello Guerra C.p. MX
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20100009788 | Ball Segment and Coupling Elements which are used to form a functional ball - The present invention relates generally to the field of toys and/or promotional articles and/or ornamental articles and more specifically to a promotional toy formed by segments of a ball and connecting elements which form a functional ball. Assembly of a complete ball using only bare hands, once all of the necessary segments are collected, is facilitated by the structure. It can be used for publicity of consumer products and has connecting means for easy assembly, which when completed allows it to be used as a ball to be kicked. The inventive ball includes a connecting system and connecting element affixed to the segment of the ball and an accessory connecting element; the fixed connecting element consisting of a projection tangential cut on the edge of the segment of the ball and on the edge having another longer projection parallel to the edge, a space being left between the peripheral edge of the segment and the inside face of the parallel projection. | 01-14-2010 |
Monika Hegi, Lausanne CH
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20110076283 | METHOD FOR PREDICTING AND DIAGNOSING BRAIN TUMOR - The present invention relates to a method for predicting or diagnosing outcome of concomitant chemo-radiotherapy of a subject suffering from brain tumor. The present invention further relates to compositions and methods for treatment or prevention of tumor resistance in a subject suffering from a brain tumor and to a kit useful for predicting or diagnosing the tumor resistance in a subject treated with concomitant chemo-radiotherapy. | 03-31-2011 |
Monika Heisterkamp, Ditzingen DE
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20110196658 | METHOD FOR TESTING THE BEHAVIOR OF A PROCESS INSTALLATION - A method for testing the behavior of a process plant as a function of the signals of a sensor, wherein the process plant includes at least one measuring chain with a measurement transmitter, which converts the sensor signal and outputs a measured value, and which has at least one sensor interface for connection of the sensor, wherein the method includes steps as follows: connecting a sensor simulator to the sensor interface for forming a test arrangement; selecting, by means of an input function on the measurement transmitter, a sensor signal to be simulated or a sequence of sensor signals to be simulated; transmitting from the measurement transmitter to the sensor simulator a selection signal corresponding to the selected sensor signal to be simulated or the selected sequence of sensor signals to be simulated; and transmitting from the sensor simulator to the measurement transmitter a simulated sensor signal assigned to the selection signal or a sequence of simulated sensor signals assigned to the selection signal. | 08-11-2011 |
Monika Henzinger, Lausanne CH
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20100325114 | SYSTEMS AND METHODS FOR DETERMINING DOCUMENT FRESHNESS - A system determines a freshness of a first document. The system determines whether a freshness attribute is associated with the first document. The system identifies, based on the determination, a set of second documents that each contain a link to the first document. The system assigns a freshness score to the first document based on a freshness attribute associated with each document of the set of second documents or the freshness attribute associated with the first document. | 12-23-2010 |
20110029542 | DOCUMENT SCORING BASED ON DOCUMENT INCEPTION DATE - A system may determine a document inception date associated with a document, generate a score for the document based, at least in part, on the document inception date, and rank the document with regard to at least one other document based, at least in part, on the score. | 02-03-2011 |
20120016874 | DOCUMENT SCORING BASED ON QUERY ANALYSIS - A system may determine an extent to which a document is selected when the document is included in a set of search results, generate a score for the document based, at least in part, on the extent to which the document is selected when the document is included in a set of search results; and rank the document with regard to at least one other document based, at least in part, on the score. | 01-19-2012 |
20120089619 | SYSTEMS AND METHODS FOR DETERMINING DOCUMENT FRESHNESS - A system determines a freshness of a first document. The system determines whether a freshness attribute is associated with the first document. The system identifies, based on the determination, a set of second documents that each contain a link to the first document. The system assigns a freshness score to the first document based on a freshness attribute associated with each document of the set of second documents or the freshness attribute associated with the first document. | 04-12-2012 |
Monika Henzinger, Corseaux CH
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20110022605 | DOCUMENT SCORING BASED ON LINK-BASED CRITERIA - A method may include receiving a document and an initial score for the document; determining that there has been a decrease in a rate or quantity of new links that point to the document over time; classifying the document as stale in response to the determining; decreasing the initial score for the document, resulting in an updated score; and ranking the document with regard to at least one other document based, at least in part, on the score. | 01-27-2011 |
20110258185 | DOCUMENT SCORING BASED ON DOCUMENT CONTENT UPDATE - A system may determine a measure of how a content of a document changes over time, generate a score for the document based, at least in part, on the measure of how the content of the document changes over time, and rank the document with regard to at least one other document based, at least in part, on the score. | 10-20-2011 |
20110264671 | DOCUMENT SCORING BASED ON DOCUMENT CONTENT UPDATE - A system may determine a measure of how a content of a document changes over time, generate a score for the document based, at least in part, on the measure of how the content of the document changes over time, and rank the document with regard to at least one other document based, at least in part, on the score. | 10-27-2011 |
20120005199 | DOCUMENT SCORING BASED ON DOCUMENT CONTENT UPDATE - A system may determine a measure of how a content of a document changes over time, generate a score for the document based, at least in part, on the measure of how the content of the document changes over time, and rank the document with regard to at least one other document based, at least in part, on the score. | 01-05-2012 |
20120016870 | DOCUMENT SCORING BASED ON QUERY ANALYSIS - A system may determine an extent to which a document is selected when the document is included in a set of search results, generate a score for the document based, at least in part, on the extent to which the document is selected when the document is included in a set of search results; and rank the document with regard to at least one other document based, at least in part, on the score. | 01-19-2012 |
20120016871 | DOCUMENT SCORING BASED ON QUERY ANALYSIS - A system may determine an extent to which a document is selected when the document is included in a set of search results, generate a score for the document based, at least in part, on the extent to which the document is selected when the document is included in a set of search results; and rank the document with regard to at least one other document based, at least in part, on the score. | 01-19-2012 |
20120016888 | DOCUMENT SCORING BASED ON QUERY ANALYSIS - A system may determine an extent to which a document is selected when the document is included in a set of search results, generate a score for the document based, at least in part, on the extent to which the document is selected when the document is included in a set of search results; and rank the document with regard to at least one other document based, at least in part, on the score. | 01-19-2012 |
20120016889 | DOCUMENT SCORING BASED ON QUERY ANALYSIS - A system may determine an extent to which a document is selected when the document is included in a set of search results, generate a score for the document based, at least in part, on the extent to which the document is selected when the document is included in a set of search results; and rank the document with regard to at least one other document based, at least in part, on the score. | 01-19-2012 |
20120023098 | DOCUMENT SCORING BASED ON QUERY ANALYSIS - A system may determine an extent to which a document is selected when the document is included in a set of search results, generate a score for the document based, at least in part, on the extent to which the document is selected when the document is included in a set of search results; and rank the document with regard to at least one other document based, at least in part, on the score. | 01-26-2012 |
20120209838 | DOCUMENT SCORING BASED ON QUERY ANALYSIS - A system may determine an extent to which a document is selected when the document is included in a set of search results, generate a score for the document based, at least in part, on the extent to which the document is selected when the document is included in a set of search results; and rank the document with regard to at least one other document based, at least in part, on the score. | 08-16-2012 |
Monika Hitzl, Salzburg AT
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20090105159 | Neuroprotective Compounds and Uses Thereof - The present invention relates to a neuroprotective compound consisting of the amino acid sequence DLHW. | 04-23-2009 |
Monika Hofmann, Mainz DE
Monika Illgner-Kurz, Herrenberg DE
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20090240797 | An On Demand Message Based Financial Network Integration Middleware - The present invention relates to distributed networking, and in particularly to a message-based networking environment. More particularly, it relates to business applications ( | 09-24-2009 |
20100125624 | COUPLING STATE AWARE SYSTEMS - A method of coupling asynchronous process interaction between computer systems integrated within an overall system of interconnected systems includes receiving a set of information describing an invocation call for execution of a first process on a first system integrated within the overall system; correlating a first callback argument received upon completion of the first process that includes a first unique identifier for the first process generated by the first system with the set of information according to the first unique identifier for the first process; and sending a notification message to a callback endpoint in a second process implemented to receive notification upon completion of the first process by the first system indicating completion of the first process. The second process executing on a second system integrated within the overall system makes the invocation call. The set of information specifies the first unique identifier and the callback endpoint. | 05-20-2010 |
Monika Kaiser, Bad Schoenbom DE
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20100082497 | Providing Foundation Application as Enterprise Services - Methods and apparatus, including systems and computer program products, for a services architecture design that provides enterprise services having foundation layer functionality at the level of an enterprise application. The design includes a set of service operations, process components, and optionally deployment units. Suitable business objects are also described. | 04-01-2010 |
Monika Kröz, Altheim-Waldhausen DE
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20080292581 | Interleukin-11 Fusion Proteins - The invention relates to proteins comprising Interleukin 11 (IL-11) (including, but not limited to, fragments and variants thereof), which exhibit thrombopoietic or antiinflammatory properties, fused to albumin (including, but not limited to fragments or variants of albumin). These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention”. These fusion proteins exhibit extended shelf-life and/or pharmacokinetic properties and/or extended or therapeutic activity. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules encoding the albumin fusion proteins of the invention, as well as vectors containing these nucleic acids, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for treatment or prophylaxis of thrombocytopenia or inflammatory diseases. | 11-27-2008 |
20100143973 | Interleukin-11 Fusion Proteins - The invention relates to proteins comprising Interleukin 11 (IL-11) (including, but not limited to, fragments and variants thereof), which exhibit thrombopoietic or anti-inflammatory properties, fused to albumin (including, but not limited to, fragments or variants of albumin). These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention”. These fusion proteins exhibit extended shelf-life and/or pharmacokinetic properties and/or extended or therapeutic activity. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules encoding the albumin fusion proteins of the invention, as well as vectors containing these nucleic acids, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for treatment or prophylaxis of thrombocytopenia or inflammatory diseases. | 06-10-2010 |
Monika Kröz, Altheim-Waldhausen DE
Patent application number | Description | Published |
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20100143973 | Interleukin-11 Fusion Proteins - The invention relates to proteins comprising Interleukin 11 (IL-11) (including, but not limited to, fragments and variants thereof), which exhibit thrombopoietic or anti-inflammatory properties, fused to albumin (including, but not limited to, fragments or variants of albumin). These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention”. These fusion proteins exhibit extended shelf-life and/or pharmacokinetic properties and/or extended or therapeutic activity. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules encoding the albumin fusion proteins of the invention, as well as vectors containing these nucleic acids, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for treatment or prophylaxis of thrombocytopenia or inflammatory diseases. | 06-10-2010 |
20120258072 | Interleukin-11 Fusion Proteins - The invention relates to proteins comprising Interleukin 11 (IL-11) (including, but not limited to, fragments and variants thereof), which exhibit thrombopoietic or anti-inflammatory properties, fused to albumin (including, but not limited to, fragments or variants of albumin). These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention”. These fusion proteins exhibit extended shelf-life and/or pharmacokinetic properties and/or extended or therapeutic activity. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules encoding the albumin fusion proteins of the invention, as well as vectors containing these nucleic acids, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for treatment or prophylaxis of thrombocytopenia or inflammatory diseases. | 10-11-2012 |
Monika Lamparska-Przyhysz, Warszawa PL
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20090264510 | Double helical oligonucleotides interfering with mRNA used as effective anticancer agents - The present invention relates to the application of double-helical oligonucleotides (siRNA) interfering with the mRNA of gene involved in carcinogenesis, particularly the Wnt1, Wnt2 or Her3 genes. Such oligonucleotides may be modified chemically, used in conjunction with viral and non-viral vectors such as lipid complexes. Such oligonucleotides exhibit unusual anti-proliferative properties against tumour cells and may be used in anti-tumour treatment. | 10-22-2009 |
Monika Maidl, München DE
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20100122086 | METHOD FOR COMBINING DATA TO BE PROCESSED WITH A DATA-SPECIFIC APPARATUS, AND APPARATUS AND COMPUTER PROGRAM FOR IMPLEMENTING THE METHOD - The invention discloses a method and a system for combining data with an apparatus which is provided for processing the data, with the following steps: (a) determining an identifier associated with the apparatus; (b) generating a first key by using the identifier and a second secret key, which is independent of the identifier; (c) generating a decryption algorithm to be used for the second key and providing the decryption algorithm to the apparatus; (d) encrypting a rights object, which allows access to the data, using the first key and the second secret key; (e) transmitting the data and the rights object to the apparatus; (f) decrypting the rights object with the apparatus by using the identifier associated with the apparatus and the decryption algorithm associated with the apparatus; and (g) decrypting the data using a key selected by a rights owner and included in the decrypted rights object. | 05-13-2010 |
Monika Medelnick, Altrip DE
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20110003685 | Polymeric Particles Capable of Absorbing Blood and/or Body Fluids - Polymeric particles capable of absorbing blood and/or body fluids, the polymeric particles being coated with at least one surfactant and with at least one solvent, are produced and used for absorbing blood and/or body fluids, especially in hygiene articles. | 01-06-2011 |
Monika Moenks, Schmitten CH
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20080223395 | Hair-Styling Foil and Method For Preparing Hair-Fixing Products in Foil Form - A method for producing a hair-fixing product in the form of a foil is described whereby first a viscous, rollable composition is prepared by dissolving or dispersing a polymer in a liquid carrier medium and then the composition is shaped into a foil by rolling it with the aid of a rolling device and the liquid carrier medium is evaporated. Also described are hair-styling foils that contain at least one hair-fixing polymer and advantageously additional surfactants or polyols and that preferably are treated with an adhering, powdered, hydrophobic release agent. | 09-18-2008 |
20090098079 | PRODUCT RELEASE SYSTEM FOR ATOMIZING COSMETIC HAIR COMPOSITIONS CONTAINING CATIONIC POLYMERS - A product release system for atomizing cosmetic hair compositions is described, which has (a) pressure-resistant packaging, (b) a capillary-containing spray head, and (c) a propellant-containing cosmetic composition, which contains at least one film-forming, hair-setting, or hair-conditioning cationic polymer. The atomization is done using the capillary. The capillary preferably has a diameter of 0.1 to 1 mm and a length of 5 to 100 mm. The spray rate is preferably 0.01 to 5 g/s. The composition can particularly be a gel, wax, or emulsion. | 04-16-2009 |
20110095103 | Product release system to atomize cosmetic hair and skin cleaning compositions - A product release system for atomizing cosmetic hair or skin cleaning compositions is described, which has (a) pressure-resistant packaging, (b) a capillary-containing spray head, and (c) a propellant-containing cosmetic composition, which contains at least one wash-active surfactant. The atomization is done using the capillary. The capillary preferably has a diameter of 0.1 to 1 mm and a length of 5 to 100 mm. The spray rate is preferably 0.01 to 5 g/s. The composition can particularly be gel-like. | 04-28-2011 |
Monika Morey, Hattingen DE
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20100070556 | Architectural Design for Data Migration Application Software - Methods, systems, and apparatus, including computer program products, for implementing a software architecture design for a software application implementing data migration. The application is structured as multiple process components interacting with each other through service interfaces, and multiple service operations, each being implemented for a respective process component. The process components include a Product Property Management process component, a Production Model Management process component, a Business Partner Data Management process component, a Product Data Maintenance process component, an Installed Base Data Management process component, a Price Master Data Management process component, an Identity Management process component, an Engineering Change Processing process component, a Migration Data Dispatching process component, and several other process components. | 03-18-2010 |
Monika Müller, Aachen DE
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20100151502 | FUNCTIONAL EXPRESSION OF TRIACYLGYLCEROL LIPASES - The present invention relates to nucleic acids that code for triacylglycerol lipases, vectors comprising said nucleic acids, host cells comprising said nucleic acids or vectors, methods for the expression of triacylglycerol lipases in prokaryotes, methods for the detection and for the production of triacylglycerol lipases, triacylglycerol lipases obtainable thereby, and the use of triacylglycerol lipase-encoding nucleic acids, vectors and recombinant host cells for said methods. | 06-17-2010 |
20100273223 | New Calb Muteins and Their Use - A protein having acrylation activity having a polypeptide sequence derived from SEQ ID NO: 1 or NO:2 by introducing at least one of the following amino acid substitutions: L278A, L278V, W104F, T42A, S47A. | 10-28-2010 |
20110257358 | METHOD FOR PREPARING E-CAPROLACTAM FROM N-ACYL-6-AMINOCAPROIC ACID - The invention relates to a method for preparing ε-caprolactam comprising deacylating N-acyl-6-aminocaproic acid and forming ε-caprolactam. The deacylation may be carried out chemically or biocatalytically. The invention further relates to a host cell, comprising a recombinant vector comprising a nucleic acid sequence encoding an enzyme capable of catalysing the formation of 6-aminocaproic acid from N-acyl-6-aminocaproic acid. | 10-20-2011 |
Monika Müller, Aachen DE
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20100151502 | FUNCTIONAL EXPRESSION OF TRIACYLGYLCEROL LIPASES - The present invention relates to nucleic acids that code for triacylglycerol lipases, vectors comprising said nucleic acids, host cells comprising said nucleic acids or vectors, methods for the expression of triacylglycerol lipases in prokaryotes, methods for the detection and for the production of triacylglycerol lipases, triacylglycerol lipases obtainable thereby, and the use of triacylglycerol lipase-encoding nucleic acids, vectors and recombinant host cells for said methods. | 06-17-2010 |
20100273223 | New Calb Muteins and Their Use - A protein having acrylation activity having a polypeptide sequence derived from SEQ ID NO: 1 or NO:2 by introducing at least one of the following amino acid substitutions: L278A, L278V, W104F, T42A, S47A. | 10-28-2010 |
Monika Niehof, Hannover DE
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20090036348 | Use of Novel HNF4a Target Genes and Their Gene Products - Dysfunction of HNF4α may lead to disease and an identification of genes targeted by this factor provides insights into mechanisms of disease. In accordance with the invention thirteen new HNF4α target genes were found (C20orf13, KIAA0774, EPS15R, PLCB1, UGTREL1, RSK4, PAK5, FMR2, NEB, NFYC, KCNQ4, PRPF3, TRPC1). These genes were identified by means of molecular biological and molecular genetic methods. The genes code for various biological functions (metabolism, regulation of cell cycle and signal transduction, differentiation, ion channels, mRNA processing, see table A) and are thus important for the therapy of metabolic disorders, diabetic diseases and tumor growth. In the present invention, additionally eleven new HNF4α target genes are described. It was shown that HNF4α and TPRC1 are regulated in animal models of diabetes. Thus, TPRC1 is a candidate gene for the treatment of diabetic nephropathy. The discovery of the above described target genes of HNF4α and their function comprises an enormous potential for the treatment of metabolic discuses including diabetes and diabetic caused diseases and tumor growth. | 02-05-2009 |
Monika Okoniewska, Princeton, NJ US
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20080292773 | Stable starches for contributing dietary fiber to food compositions - The present invention relates to the use of a modified starch to increase the dietary fiber content of food compositions processed under harsh conditions. By using certain modified starches, food formulations may be harshly processed while retaining substantial dietary fiber. Further, such modified starches provide dietary fiber without the negative effects on textural or organoleptic properties of the food compositions which are typically associated with the addition of other dietary fiber sources. | 11-27-2008 |
20100303991 | HIGH FIBER AND HIGH PROTEIN BAKED GOODS PRODUCTION - Substantially uniform hydration and dispersion of high amounts of protein and fiber are achieved while avoiding lump formation, hard textures, and off-tastes in the continuous, mass production of high protein and high fiber content sheetable doughs, and baked goods such as crackers, snacks, and cookies made from the sheeted doughs, by hydrating the protein and fiber with water at a temperature below the denaturization temperature of the proteins, and steaming the hydrated mixture without substantial gelatinization of starch during dough production. The steamed, hydrated mass may be admixed with ingredients comprising at least one flour comprising starch to obtain a dough while avoiding substantial gelatinization of starch of the at least one flour during mixing. The baked goods may have a protein content of at least about 4 g, a fiber content of at least about 4 g, and a whole grain flour content of at least about 4 g per 30 g serving. | 12-02-2010 |
20140356505 | BREAKFAST BISCUIT WITH SLOWLY AVAILABLE GLUCOSE - Methods and products related to a baked cereal product having a pre-baked SA content and a post-baked SAG content, wherein the post-baked SAG content is less than about 25% below the pre-baked SAG content. | 12-04-2014 |
Monika Oli, Gainesville, FL US
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20090087868 | Neural Proteins as Biomarkers for Nervous System Injury and Other Neural Disorders - The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 04-02-2009 |
20100047817 | Synaptotagmin and Collapsin Response Mediator Protein as Biomarkers for Traumatic Brain Injury - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological fluids after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (CSF). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 02-25-2010 |
20100196942 | BIOMARKERS OF LIVER INJURY - Novel, sensitive and specific markers for diagnostics and monitoring of liver injuries, including, but not limited to ischemic liver damage, are provided. This includes identification several enzymes of arginine/urea/nitric oxide cycle, sulfuration enzymes and spectrin breakdown related products, among others. | 08-05-2010 |
20100317041 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 12-16-2010 |
20110177974 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identities biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 07-21-2011 |
20120196307 | SYNAPTOTAGMIN AND COLLAPSIN RESPONSE MEDIATOR PROTEIN AS BIOMARKERS FOR TRAUMATIC BRAIN INJURY - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological samples after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (biological samples). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 08-02-2012 |
20140303041 | IN VITRO DIAGNOSTIC DEVICES FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention relates to an exemplary in vitro diagnostic (IVD) device used to detect the presence of and/or severity of neural injuries or neuronal disorders in a subject. The IVD device relies on an immunoassay which identifies biomarkers that are diagnostic of neural injury and/or neuronal disorders in a biological sample, such as whole blood, plasma, serum, cerebrospinal fluid (CSF). The inventive IVD device may measure one or more of several neural specific markers in a biological sample and output the results to a machine readable format wither to a display device or to a storage device internal or external to the IVD. | 10-09-2014 |
Monika Pahlke, Muenchen DE
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20110110083 | LIGHTING MODULE, LAMP AND LIGHTING METHOD - A lighting module may include a light source; a lens arranged at a distance from the light source; and a reflector; wherein the lens is configured and arranged to have a wide-angle emission characteristic and to direct a proportion of the light incident from the light source onto the reflector, wherein the proportion is at least 30%. | 05-12-2011 |
Monika Rappl, Burghausen DE
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20090260769 | METHOD FOR TREATING CELLULOSE-CONTAINING FIBERS OR PLANAR STRUCTURES CONTAINING CELLULOSE-CONTAINING FIBERS - Cellulosic substrates are treated with compound(s) containing at least two primary amino groups and compounds containing at least one β-ketocarbonyl group. The substrates exhibit good strength and hand properties. | 10-22-2009 |
Monika Reck-Glenn, Durango, CO US
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20110227254 | BIOFOAM COMPOSITIONS FOR PRODUCTION OF BIODEGRADABLE OR COMPOSTABLE PRODUCTS - The present invention provides improved compositions and methods that can be utilized to produce biofoams. Biodegradable articles made from such biofoams are also described. | 09-22-2011 |
Monika Riek-Burchardt, Kloster Neuendorf DE
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20090317325 | Diagnostic Substance and Method for the Analysis of Metabolism Processes in the Brain - The present invention relates to a diagnostic substance, containing at least one complex of lipophilic anions and metal ions, wherein the lipophilic anions are selected from the group comprising: triethylene tetramine dihydrochloride (TETA), ethyl cysteinate dimer (ECD), methoxyisobutylisonitrile (MIBI), HMPAO (d,l-hexamethylpropylene aminoxime), ethylenediamine N,N,N′,N′-tetraacetanilide (EDTAN), dimethyldithiocarbamate (DMC) and diethyldithiocarbamate (DDC) and glycine N,N′-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis [N-(carboxymethyl)-1,1′-bis[2-(octadecyloxy)ethyl]ester (DP-109), and wherein the metal ions are selected from the group comprising thallium isotopes, lead isotopes, cobalt isotopes and manganese isotopes, together with solvents, adjuvants and/or vehicles. The diagnostic substance is used for investigating metabolic processes in the brain and/or central nervous system (CNS). | 12-24-2009 |
Monika Ritsch-Marte, Innsbruck AT
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20100134869 | OPTICAL DEVICE WITH A PAIR OF DIFFRACTIVE OPTICAL ELEMENTS - The present invention provides an optical device comprising a pair of specifically designed plate-like diffractive optical elements successively arranged in parallel to each other.,. Placing the two diffractive optical elements in succession and in parallel to each other in a certain distance, the combination optically corresponds to a single diffractive optical element, and it can perform similar tasks, acting as a lens, an axicon, a phase shifter, or a spiral phase plate. If one of the diffractive optical elements is rotated with respect to the other around a common central axis, the property of the optical device, like the focal length, the refractive power, helical index, or phase shift changes continuously. | 06-03-2010 |
Monika Rusnak-Müller, Aachen DE
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20100143981 | WHOLE-CELL CATALYTIC SYSTEM COMPRISING A HYDANTOINASE, A RACEMASE AND A CARBAMOYLASE - The present invention relates to a whole cell catalytic system for the preparation of an enantiomerically enriched α-amino acid from a corresponding hydantoin wherein hydantoinase, L-carbamoylase and hydantoin racemase are coexpressed in a recombinant micro-organism wherein the genes coding for these three enzymes are located on a single replicon. The present invention further relates to the use of such a whole cell catalytic system according in the preparation of an enantiomerically enriched L-α-amino acid from a corresponding hydantoin. | 06-10-2010 |
Monika Rusnak-Müller, Aachen DE
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20100143981 | WHOLE-CELL CATALYTIC SYSTEM COMPRISING A HYDANTOINASE, A RACEMASE AND A CARBAMOYLASE - The present invention relates to a whole cell catalytic system for the preparation of an enantiomerically enriched α-amino acid from a corresponding hydantoin wherein hydantoinase, L-carbamoylase and hydantoin racemase are coexpressed in a recombinant micro-organism wherein the genes coding for these three enzymes are located on a single replicon. The present invention further relates to the use of such a whole cell catalytic system according in the preparation of an enantiomerically enriched L-α-amino acid from a corresponding hydantoin. | 06-10-2010 |
Monika Sachet, Vienna AT
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20090123495 | Immune Response Inducing Preparations - The present invention provides a pharmaceutical composition with an adjuvant based on an apathogenic virus, together with an antigen. The adjuvant has a natural or through genetical engineering no, reduced or altered expression of an endogenous interferon antagonist or endogenous immune suppressor. | 05-14-2009 |
20110268764 | IMMUNE RESPONSE INDUCING PREPARATIONS - The present invention provides a pharmaceutical composition with an adjuvant based on an apathogenic virus, together with an antigen. The adjuvant has a natural or through genetical engineering no, reduced or altered expression of an endogenous interferon antagonist or endogenous immune suppressor. | 11-03-2011 |
Monika Schaefer-Korting, Berlin DE
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20110182973 | POLYMERASE INHIBITORS AND THE USE THEREOF FOR THE TREATMENT OF TUMORS - The invention relates to polymerase inhibitors, particularly polymerase alpha inhibitors, and the use thereof in the treatment of cell growth disorders, particularly tumor disorders, preferably actinic keratoses, basal cell carcinomas, and/or spinocellular carcinomas. | 07-28-2011 |
Monika Schefzik, Steinfeld-Hausen DE
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20080257661 | Automatic Parking Brake - The invention relates to an automatic parking brake acting on a disk brake and in which the piston of the brake comprises a cavity in which there is a spring ( | 10-23-2008 |
20080269999 | Method of Adjusting an Automatic Parking Brake - The invention relates to a method of actuating an automatic parking brake for a vehicle, comprising a spring device, designed to absorb the actuating forces, situated in the actuating mechanism of a brake device. This method comprises at least the following steps: application of a preload to said spring device to a value situated in part IV of the operating characteristic, and adjustment of this preload to a level corresponding at least to a minimum braking force required for said vehicle. | 10-30-2008 |
Monika Schmiedgen, Olching DE
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20100212127 | Process for Adapting Resonance Frequency of a BAW Resonator - A method of manufacturing a filter circuit including series and parallel coupled BAW resonators is given which compensates for frequency tolerances of the resonators which are due to the manufacturing process. The new method includes measuring a resonance frequency of at least one type of the BAW resonators produced on a wafer and defining a deviation from a desired frequency. A trimming layer is then deposited onto the entire wafer. At last, a thickness portion of the trimming layer is selectively removed, the portion being dependent on a location on the wafer and on the calculated deviation of the resonance frequency at this location. | 08-26-2010 |
Monika Schmitt, Frankfurt DE
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20080254992 | 4-(3-Aminobenzoyl)-1 methylpyrazoles and their use as herbicides - What is described are 4-(3-aminobenzoyl)pyrazoles of the general formula (I) and their use as herbicides. | 10-16-2008 |
Monika Schmitt, Frankfurt A. M. DE
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20080254991 | 4-(3-Aminobenzoyl)-1-ethylpyrazoles and their use as herbicides - 4-(3-Aminobenzoyl)-1-ethylpyrazoles and their use as herbicides | 10-16-2008 |
20080305956 | 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides - What is described are 3-cyclopropyl-4-(3-thiobenzoyl)pyrazoles of the general formula (I) and their use as herbicides | 12-11-2008 |
Monika Schmitt, Frankfurt A.m. DE
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20080254990 | 4-(3-Aminobenzoyl)-1,3-dimethylpyrazoles and their use as herbicides - What is described are 4-(3-aminobenzoyl)-1,3-dimethylpyrazoles of the general formula (I) and their use as herbicides. | 10-16-2008 |
20090069184 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides - What is described are 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles of the general formula (I) and their use as herbicides. | 03-12-2009 |
Monika Singhofer-Wowra, Ladenburg DE
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20110152506 | Method for Purifying Erythropoietin - The present invention relates to a method for preparing erythropoietin, wherein culture supernatant of erythropoietin-producing eukaryotic cells containing erythropoietin are subjected to the following steps: a) Removing the cell components; and b) treating the product from a) to the following chromatography steps in the sequence indicated i) reversed phase chromatography; ii) anion exchange chromatography; iii) hydroxyapatite chromatography. | 06-23-2011 |
20110189732 | Process for the Fermentative Production of Erythropoietin - The present invention relates to a process for the fermentative continuous production of erythropoietin, where eukaryotic erythropoietin-producing cells are cultured in a perfusion reactor while retaining the cells, the glucose concentration in the culture supernatant being adjusted via the perfusion rate and the cell number via the cell retention rate and/or the outward transferal of defined amounts of cell-containing culture medium from the bioreactor within preset zones. | 08-04-2011 |
Monika Soukupova, Bernried DE
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20110053251 | REAGENTS FOR LYSIS OF BACTERIAL CELLS - The invention provides a composition containing an aqueous liquid phase, bacterial cells, and an ionic compound dissolved in the liquid phase. The ionic compound is selected from the group consisting of 1-butyl-3-methyl-imidazolium-thiocyanate, 1-butyl-3-methyl-imidazolium-2(2-methoxy-ethoxy)ethylsulfate, 1-methyl-1-[4-(3-methyl-3H-imidazol-1-ium)-but-1-yl]-3H-imidazolium-di(toluylsulfate), and 1-butyl-3-methyl-imidazolium-octylsulfate. The compositions of the invention are advantageously used for preparing lysates of biological cells, particularly bacterial cells. | 03-03-2011 |
Monika Uhlein, Berlin DE
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20090011431 | Diagnosis of Sepsis by the Selective Determination of the Concentration of Cu/Zn Superoxide Dismutase (Cu/Zn Sod) in Patient Samples - The present invention relates to a method for the early determination of the risk of mortality of patients in intensive care units or emergency care units during which the concentration of Cu/Zn superoxide dismutase (Cu/Zn SOD) in a serum sample or plasma sample of the patient is selectively determined, and quantitatively or semi-quantitatively measured concentrations, which exceed a predetermined threshold value are correlated with a high risk of mortality. | 01-08-2009 |
20090136973 | DETERMINATION OF SHORT-CHAIN SRL ALCOHOL DEHYDROGENASE (DHRS4) AS A BIOMARKER FOR INFLAMMATIONS AND INFECTIONS - The present invention relates to the use of short-chain SRL alcohol dehydrogenase (DHRS4, SEQ ID NO: 1) and peptides thereof as humoral biomarkers for the diagnostic detection and prognosis of the course, and also monitoring the course and therapy of septic inflammations and infections. | 05-28-2009 |
Monika Valtink, Dresden DE
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20090053809 | Retina-Specific Cells Differentiated In Vitro from Bone Marrow Stem Cells, the Production Thereof and Their Use - The invention relates to the production of retina-specific cells from human adult bone marrow stem cells by culturing bone marrow stem cells in the presence of a differentiation medium. The invention also relates to retina-specific cells and to the use of these cells for treating diseases associated with acquired or congenital dysfunction of the retinal pigment epithelium, cells of adjacent structures of the entire retina and of the choroid coat as well as of other eye tissue. | 02-26-2009 |
Monika Weirdl, Memphis, TN US
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20090275510 | Compositions and Methods for Inducing or Inhibiting Activities of Selected Human Cells - Polynucleotides encoding a mutant human carboxylesterase enzyme and polypeptides encoded by the polynucleotides which are capable of metabolizing a prodrug and inactive metabolites thereof to active drug are provided. Compositions and methods for sensitizing cells to a prodrug agent, inhibiting cell growth, treating drug addiction, and facilitating the metabolism of an organophosphate with this enzyme are also provided. In addition, a screening assay for identification of drugs activated by this enzyme is described. | 11-05-2009 |
20110165141 | Compositions for treating bacterial infections - Polynucleotides encoding a mutant human carboxylesterase enzyme and polypeptides encoded by the polynucleotides which are capable of metabolizing a prodrug and inactive metabolites thereof to active drug are provided. Compositions and methods for sensitizing cells to a prodrug agent, inhibiting cell growth, treating drug addiction, and facilitating the metabolism of an organophosphate with this enzyme are also provided. In addition, a screening assay for identification of drugs activated by this enzyme is described. | 07-07-2011 |
20120142108 | Compositions For Treating Bacterial Infections - Polynucleotides encoding a mutant human carboxylesterase enzyme and polypeptides encoded by the polynucleotides which are capable of metabolizing a prodrug and inactive metabolites thereof to active drug are provided. Compositions and methods for sensitizing cells to a prodrug agent, inhibiting cell growth, treating drug addiction, and facilitating the metabolism of an organophosphate with this enzyme are also provided. In addition, a screening assay for identification of drugs activated by this enzyme is described. | 06-07-2012 |
Monika Wissinger, Gilching DE
Monika Woszczyna, Pittsburgh, PA US
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20090048833 | Automated Extraction of Semantic Content and Generation of a Structured Document from Speech - Techniques are disclosed for automatically generating structured documents based on speech, including identification of relevant concepts and their interpretation. In one embodiment, a structured document generator uses an integrated process to generate a structured textual document (such as a structured textual medical report) based on a spoken audio stream. The spoken audio stream may be recognized using a language model which includes a plurality of sub-models arranged in a hierarchical structure. Each of the sub-models may correspond to a concept that is expected to appear in the spoken audio stream. Different portions of the spoken audio stream may be recognized using different sub-models. The resulting structured textual document may have a hierarchical structure that corresponds to the hierarchical structure of the language sub-models that were used to generate the structured textual document. | 02-19-2009 |
20100299135 | Automated Extraction of Semantic Content and Generation of a Structured Document from Speech - Techniques are disclosed for automatically generating structured documents based on speech, including identification of relevant concepts and their interpretation. In one embodiment, a structured document generator uses an integrated process to generate a structured textual document (such as a structured textual medical report) based on a spoken audio stream. The spoken audio stream may be recognized using a language model which includes a plurality of sub-models arranged in a hierarchical structure. Each of the sub-models may correspond to a concept that is expected to appear in the spoken audio stream. Different portions of the spoken audio stream may be recognized using different sub-models. The resulting structured textual document may have a hierarchical structure that corresponds to the hierarchical structure of the language sub-models that were used to generate the structured textual document. | 11-25-2010 |
20130103400 | Document Transcription System Training - A system is provided for training an acoustic model for use in speech recognition. In particular, such a system may be used to perform training based on a spoken audio stream and a non-literal transcript of the spoken audio stream. Such a system my identify text in the non-literal transcript which represents concepts having multiple spoken forms. The system may attempt to identify the actual spoken form in the audio stream which produced the corresponding text in the non-literal transcript, and thereby produce a revised transcript which more accurately represents the spoken audio stream. The revised, and more accurate, transcript may be used to train the acoustic model, thereby producing a better acoustic model than that which would be produced using conventional techniques, which perform training based directly on the original non-literal transcript. | 04-25-2013 |
20130304453 | Automated Extraction of Semantic Content and Generation of a Structured Document from Speech - Techniques are disclosed for automatically generating structured documents based on speech, including identification of relevant concepts and their interpretation. In one embodiment, a structured document generator uses an integrated process to generate a structured textual document (such as a structured textual medical report) based on a spoken audio stream. The spoken audio stream may be recognized using a language model which includes a plurality of sub-models arranged in a hierarchical structure. Each of the sub-models may correspond to a concept that is expected to appear in the spoken audio stream. Different portions of the spoken audio stream may be recognized using different sub-models. The resulting structured textual document may have a hierarchical structure that corresponds to the hierarchical structure of the language sub-models that were used to generate the structured textual document. | 11-14-2013 |
20140249818 | Document Transcription System Training - A system is provided for training an acoustic model for use in speech recognition. In particular, such a system may be used to perform training based on a spoken audio stream and a non-literal transcript of the spoken audio stream. Such a system may identify text in the non-literal transcript which represents concepts having multiple spoken forms. The system may attempt to identify the actual spoken form in the audio stream which produced the corresponding text in the non-literal transcript, and thereby produce a revised transcript which more accurately represents the spoken audio stream. The revised, and more accurate, transcript may be used to train the acoustic model, thereby producing a better acoustic model than that which would be produced using conventional techniques, which perform training based directly on the original non-literal transcript. | 09-04-2014 |
Monika Wyszogrodzka, Kamen DE
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20110065896 | POLYETHER POLYOL DENDRON CONJUGATES WITH EFFECTOR MOLECULES FOR BIOLOGICAL TARGETING - Subject of the present invention are polyether polyol dendron conjugates comprising a specific polyether polyol dendron moiety, at least one certain fluorescent effector molecule (E). Such polyether polyol dendron conjugates may be used for diagnostic and therapeutic purposes, whereby the optical properties of the at least one certain fluorescent effector molecule are enhanced due to the attachment to the polyether polyol dendron conjugate. | 03-17-2011 |
Monika Zatopkova, Ostrava CZ
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20080293952 | Method for the Preparation of (S)-N-Methyl-3-(1-Naphthyloxy)-3-(2-Thienyl)Propylamine Hydrochloride (Duloxetine) - A method of preparation of (S)—N-methyl-3-(1-naphthyloxy)-3-(2-mienyl)propylamine of Formula (I) and its pharmaceutically acceptable salts, comprising a) reaction of (RS)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine with optically active D-tartaric acid or an acid salt derived from D-tartaric acid forming a mixture of diastereoisomeric salts of N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine and D-tartaric acid (2:1), b) isolation of the salt (S)—N,N-dimethyl-3-(naphthyloxy)-3-(2-thienyl)propylamine/D-tartrate (2:1) from the mixture of diastereoisomeric salts in an organic solvent, water or a mixture thereof and release of (S)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine by action of an inorganic or organic base, c) demethylation of (S)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine by action of an alkylchloroformate of formula ClCOOR (R=C | 11-27-2008 |
20100069649 | METHOD OF PURIFICATION OF (S)-N-METHYL-3-(1-NAPHTYLOXY)-3-(2-THIENYL) PROPYLAMINE HYDROCHLORIDE (DULOXETINE) - A method of purification of (5)-7V-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride of formula I, comprising (a) transformation of the substance of formula I to its free base by the action of an organic or inorganic base in an aqueous environment; and (b) transformation of the base of the substance of formula I to crystalline hydrochloride by the action of hydrochloric acid or gaseous HCl in an organic solvent or a mixture of organic solvents. A method of purification of (S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride of formula I, comprising dissolution of this substance in a minimum quantity of methanol containing 0 to 50% of water and its transformation back to the solid phase (precipitation) by addition of a less polar solvent. | 03-18-2010 |
20100105919 | METHOD FOR THE PREPARATION OF ZOLMITRIPTAN - In the preparation of zolmitriptan of formula III the reduction of the diazonium salt to (5)-4-(4-hydrazinobenzyl)-1,3-oxazolidin-2-one of formula IV is performed in a more concentrated mixture and by the effect on an alkali metal disulphite, preferably sodium disulphite. A zolmitriptan toluene solvate, characterized by a toluene content of 9 to 14% by weight according to the gas chromatography determination and by a maximum of the corresponding mass loss at temperatures of about 111° C. in the gravimetric analysis record. A zolmitriptan toluene solvate, showing strong Raman bands at the wave numbers of 1443 and 1354 cm | 04-29-2010 |
20100145064 | METHOD FOR THE PREPARATION OF ZOLMITRIPTAN - A method for the preparation of zolmitriptan or its pharmaceutically acceptable salts, comprising isolation of a crystalline salt of zolmitriptan, its optional re-purification and conversion to the substance of formula (III). Zolmitriptan hydrochloride in the crystalline state. | 06-10-2010 |
20120029212 | METHOD FOR THE PREPARATION OF (S)-N-METHYL-3-(1-NAPHTHYLOXY)-3-(2-THIENYL)PROPYLAMINE HYDROCHLORIDE (DULOXETINE) - A method for the preparation of a duloxetine hydrochloride salt from a duloxetine base, comprising the steps of: reacting duloxetine base with concentrated hydrochloric acid in ethylmethylketone; and crystallizing duloxetine hydrochloride salt from said concentrated hydrochloric acid in ethylmethylketone. | 02-02-2012 |
Monika Zeraschi, Traunreut DE
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20090145891 | Ceramic Hob - A ceramic hob for a cooking appliance provided with a control device for controlling and/or adjusting a real temperature value on at least one part of a cooking plate arranged in a container for cooking by means of an associated heating device. The inventive ceramic hob comprises at least one temperature sensor for determining the real temperature value of a heatable part and at least one control element used for setting said temperature to a desired value, wherein a desired temperature value of the heatable part is assigned thereto. According to said invention several desired values can be assigned to one control element. | 06-11-2009 |
20100270288 | Device for heating food using induction and device for transmitting energy - A device for heating food using induction, including a base element having a secondary winding configured from a current conductor and a heating element that is connected to the winding. To reduce the height of the base element, a winding core is located inside the winding. Further, a device for transmitting energy to a device for heating food by induction, the former device including a primary winding that is configured from a current conductor and is connected to a voltage source. | 10-28-2010 |