Patent application number | Description | Published |
20090027050 | FREQUENCY SWEPT EXCITATION FOR MAGNETIC RESONANCE - A method of magnetic resonance is provided that uses a frequency swept excitation wherein the acquired signal is a time domain signal is provided. In one embodiment, the method comprises, applying a sweeping frequency excitation and acquiring a time domain signal. The sweeping frequency excitation has a duration and is configured to sequentially excite isochromats having different resonant frequencies. Acquisition of the time domain signal is done during the duration of the sweeping frequency excitation. The time domain signal is based on evolution of the isochromats. | 01-29-2009 |
20100253340 | ADIABATIC MAGNETIZATION PREPARATION FOR B1 AND B0 INSENSITIVE HIGH CONTRAST MRI - A magnetic resonance image is produced by radial imaging using one or more preparatory pulses. The magnetic preparation pulse can include one or more adiabatic pulses. | 10-07-2010 |
20100253341 | PULSE GAP CYCLING FOR IMPROVED SWIFT - A magnetic resonance image is produced by shifting a gap during acquisition of spin data for a specimen. The spin data is generated by a gapped excitation sequence. | 10-07-2010 |
20100315082 | FREQUENCY SWEPT EXCITATION FOR MAGNETIC RESONANCE - A method of magnetic resonance is provided that uses a frequency swept excitation wherein the acquired signal is a time domain signal is provided. In one embodiment, the method comprises, applying a sweeping frequency excitation and acquiring a time domain signal. The sweeping frequency excitation has a duration and is configured to sequentially excite isochromats having different resonant frequencies. Acquisition of the time domain signal is done during the duration of the sweeping frequency excitation. The time domain signal is based on evolution of the isochromats. | 12-16-2010 |
20110116696 | DIPOLE MATCHED FILTER FOR MRI - A method includes receiving k-space data corresponding to magnetic resonance data for a subject and selecting a template for analysis. In addition, the method includes generating an image using the k-space data and using the template. | 05-19-2011 |
20110288398 | SHORT TE 3D RADIAL SAMPLING SEQUENCE FOR MRI - A method for magnetic resonance imaging includes providing a radio frequency excitation pulse to a specimen. The pulse has a duration. The method includes, concurrent with providing the radio frequency excitation pulse, applying a first gradient having a first polarity. The method includes applying a readout gradient at a time after the duration. The readout gradient has inverse polarity relative to the first polarity. The method includes, concurrent with applying the readout gradient, acquiring magnetic resonance data from the specimen. The method includes generating an image based on the magnetic resonance data. | 11-24-2011 |
20120092010 | LOCALISATION OF MAGNETIC PARTICLES BY MEANS OF SWIFT-MRI - Positive contrast localization of magnetic (e.g. superparamagnetic) particles in vivo or in vitro by means of SWIFT-MRI using the imaginary component of MR image data in combination with an anatomic reference image derived from the real or magnitude component. | 04-19-2012 |
20130043867 | SIDEBAND PROCESSING FOR MAGNETIC RESONANCE - A method includes applying a pulse train to a spin system in a scanner. The pulse train has a plurality of discontinuities in a time domain. The method includes receiving a response from the spin system. The response corresponds to a gated signal. The method includes accessing a correction factor corresponding to the scanner. The method includes calculating a correction to the response based on the correction factor. The method includes generating an output based on the correction. | 02-21-2013 |
20130084023 | MULTISTEP CORRECTION FOR ANGLE CONSISTENT ARTIFACTS IN RADIAL SAMPLED DATASETS - This document discloses, among other things, a method for removing a bullseye artifact from a radial image generated using magnetic resonance and using a swept frequency pulse. | 04-04-2013 |
20130085374 | METHOD OF OSCILLOGRAM FILTERING FOR RADIAL MRI DATA - A system includes a data receiver, a sinogram generator, a processor, a filter module, and an output module. The data receiver is configured to receive radial ordered magnetic resonance data. The sinogram generator is configured to generate a first sinogram corresponding to a view angle as a function of a readout direction for the magnetic resonance data. The processor is configured to generate an oscillogram having an angular frequency axis. The oscillogram corresponds to a Fourier transform of the first sinogram. The filter module is configured to selectively filter a peak in a projection formed along a selected axis of the oscillogram, the peak being related to an interference signal such as an RF interference. The selected axis is orthogonal to the angular frequency axis. The output module is configured to form a second sinogram corresponding to a transform of the filtered projection | 04-04-2013 |
20130271133 | STEERING RESONANCE ALONG A TRAJECTORY - A method for generating a magnetic resonance image includes applying a radio frequency (RF) pulse to a specimen. The method includes modulating a spatially varying magnetic field to impart an angular velocity to a trajectory of a region of resonance relative to the specimen. The method includes acquiring data corresponding to the region of resonance and reconstructing a representation of the specimen based on the data. | 10-17-2013 |
20130320980 | PULSE GAP CYCLING FOR IMPROVED SWIFT - A magnetic resonance image is produced by shifting a gap during acquisition of spin data for a specimen. The spin data is generated by a gapped excitation sequence. | 12-05-2013 |
Patent application number | Description | Published |
20100317050 | POLYPEPTIDES FOR MICROBIAL DETECTION - Polypeptides which can be activated to cause the formation of pores in a lipid membrane are disclosed. Also disclosed are polypeptide compositions for the detection of target microorganisms and methods of using said compositions. | 12-16-2010 |
20120252049 | METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE - A method of detecting microorganisms in a test sample is provided. The method includes the steps of: a) incubating the test sample with a growth media to form an incubated sample, wherein the growth media includes an enzyme substrate and the enzyme substrate includes an enzymatically hydrolysable group and a fluorescent group, wherein microorganisms present in the test sample include an enzyme that hydrolyzes the hydrolysable group from the fluorescent group to form a fluorescently detectable product, wherein the fluorescently detectable product has both an acidic and basic species; b) exciting the fluorescently detectable product with light having a wavelength of Exλiso for a time sufficient for the fluorescently detectable product to emit light, wherein Exλiso is the absorbance isosbestic point of the fluorescently detectable product; and c) detecting light emitted at a wavelength of Emλ1. | 10-04-2012 |
20120288888 | MICROBIAL DETECTION ARTICLE - The disclosure provides an article for the detection of a microorganism in a liquid sample. The article comprises a microporous membrane and a barrier layer to selectively regulate the contact between the sample and a detection reagent. A method of use is also provided. | 11-15-2012 |
20120301911 | Rapid Detection of Molds that Produce Glucose Oxidase - Methods and kits are disclosed for detecting microorganisms that produce glucose oxidase. The method includes providing a culture medium and a hydrogen peroxide indicating reagent comprising a chromogenic substrate that can provide a detectable chromogenic reaction indicating the presence of a microorganism that produces glucose oxidase, and additional methods are disclosed for differentiating microorganisms by the detection of an additional chromogenic reaction. | 11-29-2012 |
20130089923 | DEVICE FOR RAPIDLY DETECTING MICROORGANISMS - The disclosure includes: a coating composition, comprising a powdered cold-water-soluble gelling agent and surface-modified nanoparticles disposed in the powdered cold-water-soluble gelling agent; a coated film that includes a transparent film coated with the coating composition; and a device for growing microorganisms, including the coated film releasably attached to at least a portion of a body member that includes a self-supporting and water-proof substrate. | 04-11-2013 |
20130230876 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY - Compositions that comprise water, a first indicator reagent that can be converted by a first biological activity to a first biological derivative, and a plurality of particles are provided. The first indicator reagent can comprise a fluorogenic enzyme substrate having a fluorophore selected from the group consisting of umbelliferone, 7-aminocoumarin, β-naphthylamine, β-naphthol, fluorescein, resorufin, 9H-(1,3-dichloro-9,9-dimethyl acridin-2-one), rhodamine 110, a derivative of any of the foregoing fluorophores, and a combination of any of the foregoing fluorophores. The particles are capable of receiving and retaining the first biological derivative from an aqueous liquid. The first biological derivative can be indicative of a microorganism. The compositions further can comprise a gelling agent. Methods of using the compositions to detect the presence or absence of a microorganism in a sample are also provided. | 09-05-2013 |
20130309693 | POLYPEPTIDES FOR MICROBIAL DETECTION - Polypeptides which can be activated to cause the formation of pores in a lipid membrane are disclosed. Also disclosed are polypeptide compositions for the detection of target microorganisms and methods of using said compositions. | 11-21-2013 |
20130316443 | SYSTEM FOR DETECTING MICROORGANISMS - A system for detecting microorganisms in a test sample is provided that includes a fluorescently detectable product having both acidic and basic species, wherein the fluorescently detectable product is the reaction product of (a) an enzyme substrate that comprises an enzymatically hydrolysable group and a fluorescent group and (b) a test sample comprising a microorganism having an enzyme that hydrolyzes the hydrolysable group from the fluorescent group of the enzyme substrate. The fluorescently detectable product has an excitation isosbestic point Exλiso where the absorbance of the acid species is the same as the absorbance of the basic species. The system also includes a first light source having a wavelength of Exλiso for irradiating the fluorescently detectable product, The fluorescently detectable product emits light at a wavelength of Emλ1, and the quantity of light emitted at the wavelength Emλ1 is substantially constant across a pH range of 2.5 to 8.0. | 11-28-2013 |
20140186878 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF - Compounds are provided that are either fluorogenic or fluorophoric. Compositions and articles that include the compounds are also provided. Additionally, methods of detecting a microorganism using the compounds are provided. The compounds are fluorinated and can be used advantageously under acidic conditions. | 07-03-2014 |