Patent application number | Description | Published |
20130096687 | Artificial Hemi-Lumbar Interbody Spinal Fusion Cage Having an Asymmetrical Leading End - An artificial interbody spinal implant adapted for placement across an intervertebral space formed across the height of a disc space between two adjacent vertebral bodies is disclosed. The implant has an asymmetrical leading end adapted to sit upon the more peripheral areas, such as the apophyseal rim and the apophyseal rim area, of the vertebral end plate region of the vertebral bodies without protruding therefrom. The asymmetrical leading end allows for the sate use of an implant of maximum length for the implantation space into which it is installed. The implant can also include an asymmetric trailing end adapted to sit upon the more peripheral areas of the vertebral end plate region of the vertebral bodies. | 04-18-2013 |
20130096688 | Interbody Spinal Fusion Implant Having A Trailing End With At Least One Stabilization Element - A flanged interbody spinal fusion implant for insertion at least in part between adjacent vertebral bodies has opposed upper and lower surfaces adapted to contact each of the adjacent vertebral bodies from within the disc space, a leading end for insertion between the adjacent vertebral bodies, and a trailing end opposite the leading end. The trailing end has a height greater than the maximum height of the disc space forming a flanged portion adapted to overlie a part of the anterior aspects of the vertebral bodies adjacent and proximate the disc space to be fused. The flanged portion has at least two bone screw receiving holes, at least one each adapted to overlie each of the adjacent vertebral bodies at least in part. The implant has at least one locking element to lock one or more of the bone screws inserted in the bone screw receiving holes. Instrumentation for inserting the implant, forming screw holes in the vertebral body, and for locking the locking elements are disclosed. | 04-18-2013 |
20130204300 | SINGLE-LOCK ANTERIOR CERVICAL PLATE - Anatomically contoured anterior cervical plates with bone ingrowth surfaces, providing for intersegmental compressive preloading, and a rigid and locked interface to all of the bone screws, with those engaging the vertebrae deployed in highly convergent pairs. The bone screws have a tapered self-tapping leading end, an increasing root diameter with a generally constant outer diameter with a thread that is narrow and sharp throughout and an enlarged head portion capable of an interference fit to the receiving holes of the plate. Instrumentation consists of plate holders, a compression apparatus and a pilot hole forming device that interlocks with the plate. Methods for spinal compression and bone hole preparation are provided. | 08-08-2013 |
20130218279 | PUSH-IN INTERBODY SPINAL FUSION IMPLANTS FOR USE WITH SELF-LOCKING SCREWS - An apparatus including an interbody spinal fusion implant having a leading end, a trailing end, and a length therebetween, and opposed upper and lower portions adapted to contact each of the adjacent vertebral bodies. Each of the upper and lower portions having at least one opening adapted to communicate with one each of the adjacent vertebral bodies and to communicate with one another to permit for the growth of bone from vertebral body to adjacent vertebral body through the implant. Each of the upper and lower portions has at least one screw hole passing therethrough proximate the trailing end. The apparatus further includes bone screws adapted for placement through the screw holes of the upper and lower portions and into each of the adjacent vertebral bodies adjacent the disc space to be fused and into which the implant is adapted to be positioned. At least one lock may be used to prevent the bone screws from backing out of the vertebral bodies and implant. | 08-22-2013 |
20130245771 | METHOD FOR LOADING A SPINAL IMPLANT - A method for loading a spinal implant with fusion promoting substances into an implantation space adjacent vertebral bodies of the spine. | 09-19-2013 |
20130296942 | ORTHOPEDIC IMPLANT WITH LOCKING ELEMENT - An orthopedic implant with a locking element for locking a bone screw in a bone screw receiving hole of the implant. | 11-07-2013 |
20140067074 | SPINAL IMPLANT HAVING DEPLOYABLE BONE ENGAGING PROJECTIONS - Instrumentation is disclosed for inserting an interbody spinal fusion implant for implantation at least in part within and across the generally restored height of a disc space between two adjacent vertebral bodies of a human spine. The implant has an external housing and a substantially hollow internal rotatable member having bone engaging projections that are deployable through the housing to penetrably engage the adjacent vertebral bodies. | 03-06-2014 |
20140265461 | ADJUSTABLE CHILD BOOSTER SEAT - An adjustable height child booster seat including a seat and a base configured to be placed on an elevated surface above ground. The seat may be rotated relative to the base to move the seat and the base relative to each other in to adjust the booster seat to a desired height. | 09-18-2014 |
20140265487 | ADJUSTABLE CHILD BOOSTER SEAT - An adjustable booster seat including a seat and a base configured to be placed on an elevated surface above ground. The seat may be rotated relative to the base to move the seat and the base relative to each other in to adjust the booster seat to a desired height. | 09-18-2014 |
20140316476 | Method for Using a Guard for Creating a Socket Posteriorly in the Lumbar Spine - A method for guiding a bone removal device to form a socket in the human spine and for inserting a cortical bone implant into the socket. The method includes placing a guard against the posterior aspect of the spine, the guard having a passage therethrough, inserting the bone removal device into the passage, removing a portion of a facet joint with the bone removal device to create the socket having a maximum height, and inserting the cortical bone implant into the socket. The cortical bone implant has a leading end, a trailing end, a mid-longitudinal axis through the ends, and a height transverse to the mid-longitudinal axis, the height of the cortical bone implant being greater than the maximum height of the socket. | 10-23-2014 |
20150127108 | SPINAL FUSION IMPLANT WITH BONE SCREWS AND A BONE SCREW LOCK - An interbody spinal fusion implant made of a material other than bone adapted for placement across an intervertebral space formed across the height of a disc space between two adjacent vertebral bodies. The implant has a trailing end with a bone screw receiving hole for receiving at least one bone screw to engage the vertebral bodies. | 05-07-2015 |
20160100873 | Method for Using a Guard for Creating a Socket Posteriorly in the Spine - A method for guiding a bone removal device to form a socket in the human spine and for inserting a cortical bone implant into the socket. The method includes placing a guard against the posterior aspect of the spine, the guard having a passage therethrough, inserting the bone removal device into the passage, removing a portion of a facet joint with the bone removal device to create the socket having a maximum height, and inserting the cortical bone implant into the socket. The cortical bone implant has a leading end, a trailing end, a mid-longitudinal axis through the ends, and a height transverse to the mid-longitudinal axis, the height of the cortical bone implant being greater than the maximum height of the socket. | 04-14-2016 |
Patent application number | Description | Published |
20080255564 | Bone cutting device - Apparatus and a method of inserting spinal implants is disclosed in which an intervertebral space is first distracted, a hollow sleeve having teeth at one end is then driven into the vertebrae adjacent that disc space. A drill is then passed through the hollow sleeve removing disc and bone in preparation for receiving the spinal implant which is then inserted through the sleeve. | 10-16-2008 |
20080287955 | Distractor for use in spinal surgery and method of use thereof - Apparatus and a method of inserting spinal implants is disclosed in which an intervertebral space is first distracted, a hollow sleeve having teeth at one end is then driven into the vertebrae adjacent that disc space. A drill is then passed through the hollow sleeve removing disc and bone in preparation for receiving the spinal implant which is then inserted through the sleeve. | 11-20-2008 |
20090088857 | Implant for the delivery of electrical current to promote bone growth between adjacent bone masses - An electrical bone growth promotion apparatus for the delivery of electrical current to an implant surgically implanted between adjacent bone masses to promote bone growth to areas adjacent to the implant is disclosed. The apparatus of the present invention comprises a self contained implant having a surgically implantable, renewable power supply and related control circuitry for delivering electrical current directly to the implant and thus directly to the area in which the promotion of bone growth is desired. The desired areas of bone growth promotion may be controlled by conducting negative charge only to the desired location of bone growth promotion. | 04-02-2009 |
20100217394 | Frusto-conical spinal implant - The present invention is directed to a variety of interbody spinal fusion implants having at least a partially frusto-conical configuration. The spinal fusion implants of the present invention may be relatively solid or hollow and may have surface roughenings to promote bone ingrowth and stability. The spinal fusion implants of the present invention may have wells extending into the material of the implant from the surface for the purpose of holding fusion promoting materials and to provide for areas of bone ingrowth fixation. A variety of surface irregularities may be employed to increase implant stability and implant surface area, and/or for the purpose of advancing the spinal fusion implant into the fusion site. | 08-26-2010 |
20110004310 | Lordotic interbody spinal fusion implants - The present application is directed to interbody spinal fusion implants having a structural configuration that provides for the maintaining and creating of the normal anatomic angular relationship of two adjacent vertebrae of the spine to maintain and create spinal lordosis. The spinal fusion implants are sized to fit within the disc space created by the removal of disc material between two adjacent vertebrae and conform wholly or in part to the disc space created. The spinal fusion implants of the present invention have upper and lower surfaces that form a support structure for bearing against the end plates of the adjacent vertebrae. The upper and lower surfaces are disposed in a converging angular relationship to each other such that the implants have an overall “wedged-shape” in an elevational side view. The angular relationship of the upper and lower surfaces places and maintains the vertebrae adjacent to those surfaces in an angular relationship to each other, creating and maintaining the desired lordosis. | 01-06-2011 |
20110054529 | THREADED INTERBODY SPINAL FUSION IMPLANT - The present invention is directed to a variety of interbody spinal fusion implants having at least a partially frusto-conical configuration. An external thread is employed to increase implant stability and implant surface area, and for the purpose of advancing the spinal fusion implant into the fusion site. The spinal fusion implants of the present invention may be relatively solid or hollow and may have surface roughenings to promote bone ingrowth and stability. The spinal fusion implants of the present invention may have wells extending into the material of the implant from the surface for the purpose of holding fusion promoting materials and to provide for areas of bone ingrowth fixation. | 03-03-2011 |
20110137420 | EXPANDABLE PUSH-IN ORTHOPEDIC IMPLANT - A push-in orthopedic implant having an expandable height. The implant includes an upper member, a lower member, and a blocker pivotally attached to one of the upper and lower members. The blocker is attached proximate one of the proximal and distal ends of the one of the upper and lower members, and is adapted to pivot into cooperative engagement with another of the one of the upper and lower members. The blocker is adapted to hold at least a portion of the upper and lower members apart so as to maintain an increased height of the implant and resist the collapse of the implant to a collapsed implant height when the implant is in a final deployed position. | 06-09-2011 |
20110196501 | INTERBODY SPINAL IMPLANT INDUCTIVELY COUPLED TO AN EXTERNAL POWER SUPPLY - An electrical bone growth promotion apparatus for the delivery of electrical current to an implant surgically implanted between adjacent bone masses to promote bone growth to areas adjacent to the implant is disclosed. The apparatus of the present invention comprises a self contained implant having a surgically implantable, renewable power supply and related control circuitry for delivering electrical current directly to the implant and thus directly to the area in which the promotion of bone growth is desired. The desired areas of bone growth promotion may be controlled by conducting negative charge only to the desired location of bone growth promotion. | 08-11-2011 |
20110224795 | SPINAL FUSION IMPLANT - The present invention is directed to a variety of interbody spinal fusion implants for insertion across the surgically corrected height of a disc space between two adjacent vertebral bodies of a human spine. The spinal fusion implants of the present invention have opposed upper and lower portions with openings extending through the implant to provide for bone growth from vertebral body to vertebral body. The upper and lower portions of the spinal fusion implants of the present invention have bone engaging projections to engage the implants to the adjacent vertebral bodies. | 09-15-2011 |
20110270318 | DEVICE AND METHOD FOR RESILIENTLY LOCKING A SCREW TO A PLATE - A spinal fixation device for stabilizing one or more segments of the human spine and for preventing the dislodgement of intervertebral spinal fusion implants, which remains permanently fixated once applied. | 11-03-2011 |
20120071982 | Anatomic spinal implant having anatomic bearing surfaces - The present application is directed to an interbody spinal implant having a structural configuration that provides for maintaining the normal anatomic relationship of two adjacent vertebrae of the spine. The spinal implant is sized to fit within the disc space created by the removal of disc material between two adjacent vertebrae and conform wholly, or in part, to the disc space created. The spinal implant of the present invention has first and second sides with upper and lower bearing surfaces that form a support structure for bearing against the end plates of the adjacent vertebrae. The upper and lower bearing surfaces of the first and second sides are shaped to create an anatomic fit with the endplates of the adjacent vertebrae. | 03-22-2012 |
20120071984 | METHOD FOR INSERTING AN ARTIFICIAL IMPLANT BETWEEN TWO ADJACENT VERTEBRAE ALONG A CORONAL PLANE - A method for inserting an artificial implant between two adjacent vertebrae along a corona plane, | 03-22-2012 |
20120209331 | DEVICE AND METHOD FOR LOCKING A SCREW WITH A BENDABLE PLATE PORTION - A spinal device for stabilizing adjacent vertebral bodies of the human spine. The device includes a combination of a screw and a member having a screw hole and a length sufficient to span a disc space between the adjacent vertebral bodies. The member has a portion that is bendable or deformable to prevent the outward excursion of the screw from the screw hole of the member. | 08-16-2012 |
20120290092 | SPINAL IMPLANTS - The present invention is directed to a variety of spinal implants. | 11-15-2012 |
20120323331 | SPINAL IMPLANT AND INSTRUMENTS - A kit including an artificial implant for insertion between two adjacent vertebrae along a coronal plane. | 12-20-2012 |
Patent application number | Description | Published |
20110008371 | METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OX- O-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF ANTECEDENT HEMATOLOGIC DISORDERS - Methods of treating, preventing or managing antecedent hematologic disorders, such as myelodysplastic syndrome, including chronic myelomonocytic leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with cytarabine. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed. | 01-13-2011 |
20130102559 | METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OX- O-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF ANTECEDENT HEMATOLOGIC DISORDERS - Methods of treating, preventing or managing antecedent hematologic disorders, such as myelodysplastic syndrome, including chronic myelomonocytic leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with cytarabine. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed. | 04-25-2013 |
20150190380 | METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OX- O-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF CERTAIN HEMATOLOGIC DISORDERS - Methods of treating, preventing or managing hematologic disorders, such as leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with Ara-C. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed. | 07-09-2015 |
20150250775 | METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OX- O-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF ANTECEDENT HEMATOLOGIC DISORDERS - Methods of treating, preventing or managing antecedent hematologic disorders, such as myelodysplastic syndrome, including chronic myelomonocytic leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with cytarabine. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed. | 09-10-2015 |
Patent application number | Description | Published |
20090318775 | METHODS AND SYSTEMS FOR ASSESSING CLINICAL OUTCOMES - Described herein are methods and systems useful for characterizing clinical outcomes of a subject. Provided herein includes computer-assessed methods, medical information systems, and computer-readable instructions that can aid an end-user in diagnosis, prognosis, and treatment of a clinical outcome. | 12-24-2009 |
20130185089 | METHODS AND SYSTEMS FOR ASSESSING CLINICAL OUTCOMES - Described herein are methods and systems useful for characterizing clinical outcomes of a subject. Provided herein includes computer-assessed methods, medical information systems, and computer-readable instructions that can aid an end-user in diagnosis, prognosis, and treatment of a clinical outcome. | 07-18-2013 |
20140046683 | Methods and Systems for Assessing Clinical Outcomes - Described herein are methods and systems useful for characterizing clinical outcomes of a subject. Provided herein includes computer-assessed methods, medical information systems, and computer-readable instructions that can aid an end-user in diagnosis, prognosis, and treatment of a clinical outcome. | 02-13-2014 |
Patent application number | Description | Published |
20080213786 | Treatment of rheumatoid arthritis with galectin-3 antagonists - The invention encompasses a novel method of treating an inflammatory disease, such as rheumatoid arthritis, and novel methods of identifying and screening for drugs useful in the treatment of inflammatory diseases, such as rheumatoid arthritis, and their clinical symptoms. The inventors have made the discovery that the activity of galectin-3, a β-galactoside-binding lectin known to have an effect on some cancers, has a significant impact on the pathophysiology of rheumatoid arthritis. The symptoms of an inflammatory disease, such as rheumatoid arthritis, may be alleviated by administering a compound that inhibits the activity of galectin-3. | 09-04-2008 |
20110093249 | INTEGRATED HEALTH DATA CAPTURE AND ANALYSIS SYSTEM - The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be used to monitor infectious and chronic diseases. When faced with outbreak of an infectious disease agent, e.g., influenza virus, the system can identify active cases through pro-active sampling in high risk locations, such as schools or crowded commercial areas. The system can notify appropriate entities, e.g., local, regional and national governments, when an event is detected, thereby allowing for proactive management of a possible outbreak. The system also predicts the best response for deployment of scarce resources. | 04-21-2011 |