Patent application number | Description | Published |
20090269673 | Process for the preparation of compounds containing perfluoroalkanesulfonic acid groups - The invention relates to a method for producing perfluoroalkanesulfonic acid esters and for further transforming the same into the salts thereof. The invention also relates to the use of the produced compounds in electrolytes, batteries, capacitors, supercapacitors, and galvanic cells. | 10-29-2009 |
20110045359 | Reactive ionic liquids - The invention relates to reactive ionic liquids containing organic cations with groups or substituents which are susceptible to electrochemical reduction and anions obtained from fluoroalkyl phosphates, fluoroalkyl phosphinates, fluoroalkyl phosphonates, acetates, triflates, imides, methides, borates, phosphates and/or aluminates, for use in electrochemical cells, such as lithium ion batteries and double-layer capacitors. | 02-24-2011 |
20120127631 | ELECTROLYTE SYSTEM - The present invention relates to electrolyte systems and electrochemical cells comprising conductive salts having different anionic and/or cationic radii. | 05-24-2012 |
20130316248 | Process for the preparation of compounds containing perfluoroalkanesulfonic acid groups - The invention relates to a method for producing perfluoroalkanesulfonic acid esters and for further transforming the same into the salts thereof. The invention also relates to the use of the produced compounds in electrolytes, batteries, capacitors, supercapacitors, and galvanic cells. | 11-28-2013 |
20140193707 | SULFUR-CONTAINING ADDITIVES FOR ELECTROCHEMICAL OR OPTOELECTRONIC DEVICES - The invention relates to sulfur-containing compounds of the formula I, to their preparation, and to their use as additives in electrochemical or electrooptical devices, more particularly in electrolytes for lithium batteries, lithium ion batteries, double layer capacitors, lithium ion capacitors, solar cells, electrochromic displays, sensors and/or biosensors. | 07-10-2014 |
20150152045 | REACTIVE IONIC LIQUIDS - The invention relates to reactive ionic liquids containing organic cations with groups or substituents which are susceptible to electrochemical reduction and anions obtained from fluoroalkyl phosphates, fluoroalkyl phosphinates, fluoroalkyl phosphonates, acetates, triflates, imides, methides, borates, phosphates and/or aluminates, for use in electrochemical cells, such as lithium ion batteries and double-layer capacitors. | 06-04-2015 |
20150236380 | USE OF FLUOROISOPROPYL DERIVATIVES AS ADDITIVES IN ELECTROLYTES - An electrolyte composition (A) containing (i) at least one aprotic organic solvent; (ii) at least one conducting salt; (iii) at least one compound of formula (I) wherein A | 08-20-2015 |
Patent application number | Description | Published |
20090304030 | TRANSMISSION CIRCUIT AND METHOD FOR TRANSMITTING A BIT SEQUENCE TO BE TRANSMITTED - A transmission circuit and method for transmitting a bit sequence to be transmitted is provided that includes a dividing device for dividing the bit sequence into an even-numbered bit sequence and into an odd-numbered bit sequence, a first device for forming the first sampled values of a first fundamental wave depending on the even-numbered bit sequence, a second device for forming second sampled values of a second fundamental wave depending on the odd-numbered bit sequence, the second fundamental wave being shifted relative to the first fundamental wave by a time period, and includes a summator for summation of the first sampled values of the first fundamental wave and the second sampled values of the second fundamental wave to form an output value sequence. | 12-10-2009 |
20100103000 | METHOD FOR RATE INCREASE AND METHOD FOR RATE REDUCTION - A method for a rate increase and a method for a rate reduction of a sampling input sequence into a sampling output sequence is provided. The sampling input sequence is subjected to signal processing. Signal processing maps a spreading with a first factor and an interpolation and a decimation with a second factor to generate the sampling output sequence with use of a counter. The counter and the signal processing are clocked with the higher rate, in each case, of the sampling input sequence or the sampling output sequence, respectively. | 04-29-2010 |
20100329139 | CIRCUIT OF A NODE AND METHOD FOR TRANSIT TIME MEASUREMENT IN A RADIO NETWORK - A circuit of a node in a radio network and method for transit time measurement between a first node and a second node of a radio network is provided. A frame is transmitted by the first node, wherein the frame requires an acknowledgment of reception by the second node. A first point in time of the transmission of the frame is established by the first node by a time counter. The frame is received by the second node at a second point in time. The acknowledgment is transmitted by the second node to the first node at a third point in time, wherein the third point in time depends on the second point in time by a predetermined time interval between the second point in time and the third point in time. A fourth point in time is established by the first node by the time counter when the acknowledgment is received. The transit time or the change in transit time is determined from the first point in time established by the time counter and from the established fourth point in time and from the predetermined time interval. | 12-30-2010 |
20120045016 | Transmission Circuit and Method for Transmitting a Bit Sequence to be Transmitted - A transmission circuit and method for transmitting a bit sequence to be transmitted is provided that includes a dividing device for dividing the bit sequence into an even-numbered bit sequence and into an odd-numbered bit sequence, a first device for forming the first sampled values of a first fundamental wave depending on the even-numbered bit sequence, a second device for forming second sampled values of a second fundamental wave depending on the odd-numbered bit sequence, the second fundamental wave being shifted relative to the first fundamental wave by a time period, and includes a summator for summation of the first sampled values of the first fundamental wave and the second sampled values of the second fundamental wave to form an output value sequence. | 02-23-2012 |
20120106529 | Transmitting Data Between Nodes of a Wireless Network - In one embodiment, setting, by a first node, a settable data rate for a first part of a data frame, the data frame also having a second part having a defined second data rate, and transmitting, by the node, the first part at the set data rate and the second part at the second data rate, the first part including at least a portion of a payload of the data frame and the second part including an identifier based on the set data rate. | 05-03-2012 |
20120314815 | Method and Receiving Unit for the Detection of Data Symbols - A method and device is provided for detecting data symbols in a received radio signal. Each data symbol is allocated transmit-side a symbol value-specific PN sequence of successive PN chips in the chip clock, and the allocated PN sequences are offset QPSK modulated. The method for incoherent detection includes converting the received radio signal into a complex baseband signal sampled in the chip clock, generating a demodulated signal by differential demodulation of the complex baseband signal, calculating correlation results by correlating the demodulated signal with the derived sequences, and deriving the values of the data symbols by evaluating the correlation results. Each derived sequence is assigned to a PN sequence allocable transmit-side and includes derived chips, whose values correspond to a logic linking of particular PN chips of the PN sequence allocable transmit-side that is assigned the derived sequence. The invention relates furthermore to a corresponding receiving unit. | 12-13-2012 |
Patent application number | Description | Published |
20080264609 | HEAT EXCHANGER FOR EXHAUST GAS COOLING; METHOD FOR OPERATING A HEAT EXCHANGER; SYSTEM WITH A HEAT EXCHANGER FOR EXHAUST GAS COOLING - A heat exchanger, in particular for cooling the exhaust of a motor vehicle internal combustion engine, is disclosed, the heat exchanger comprising a first partial heat exchanger with at least one first flow channel through which a medium to be cooled is to flow and at least one third flow channel through which a first coolant is to flow, at least one second partial heat exchanger with at least one second flow channel through which a medium to be cooled is to flow and at least one fourth flow channel through which a second coolant is to flow, wherein the at least one first flow channel and the at least one second flow channel are fluidly connected, and the at least one first flow channel and the at least one second flow channel have at least one first specific heat transfer surface and at least one second heat transfer surface, wherein second specific heat transfer surface area, divided by first specific heat transfer surface area, yields a quotient (ψ), the at least one first flow channel having a larger quotient (ψ) than second flow channel. | 10-30-2008 |
20100025023 | HEAT EXCHANGER, EXHAUST GAS RECIRCULATION SYSTEM, AND USE OF A HEAT EXCHANGER - A heat exchanger, particularly an exhaust gas heat exchanger, for transferring heat in two stages between a first fluid and a second and third fluid that have different temperatures is provided. The heat exchanger comprises a block for separately conducting the first as well as the second and third fluid in a heat transferring manner. The block encompasses a number of ducts through which the first fluid can flow, a first chamber of a high-temperature part, through which the second fluid can flow and which accommodates the ducts, a second chamber of a low-temperature part, through which the third fluid flows and which accommodates the ducts, and a housing in which the first and second chamber as well as the ducts are arranged. Thus, a two-stage heat exchanger is provided at a low cost and keeps leakage between the high-temperature part and the low-temperature part low. Whereby the first chamber and the second chamber are separated from one another by means of a separation area that is mounted in a groove. | 02-04-2010 |
20100139631 | HEAT EXCHANGER - The invention relates to a heat exchanger with at least one duct, which can be flowed through by flowing medium from an inlet cross-section to an outlet cross-section, has an inside and outside, and which comprises, on the inside, structural elements for increasing the transfer of heat. The invention provides that the structural elements ( | 06-10-2010 |
20100199650 | DEVICE FOR EXHAUST GAS RECIRCULATION FOR A COMBUSTION ENGINE - A device for exhaust gas recirculation for a combustion engine is provided that includes an exhaust gas pipe configured to conduct exhaust gas and a channel configured to conduct air to the combustion engine. The exhaust gas pipe terminates in the channel, wherein the exhaust gas pipe, in an area of insertion in the channel exhaust, is in thermal exchange with a coolant from a coolant circuit. | 08-12-2010 |
20100282452 | DEVICE FOR THE EXCHANGE OF HEAT AND MOTOR VEHICLE - A device for the exchange of heat between a first and a second medium with pairs of trays stacked one on top of the other in a stacking direction is provided, wherein a first flow chamber that can be flowed through by a first medium is provided between the two trays of at least one pair of trays or several pairs of trays and a second flow chamber that can be flowed through by a second medium is provided between two pairs of trays adjacent to one another, wherein the first flow chamber has first flow path with flow path sections that can be flowed through consecutively in opposite directions for the first medium, which are separated from one another by a division wall arranged between the at least two trays of the at least one pair of trays, and wherein the second flow chamber has a second flow path for the second medium. | 11-11-2010 |
20100319887 | HEAT-EXCHANGING DEVICE AND MOTOR VEHICLE - An exhaust gas installation is provided that comprises an exhaust gas evaporator mounted downstream of an internal combustion engine of a motor vehicle. The exhaust gas evaporator has a sandwich-type structure wherein exhaust gas planes and coolant planes are alternately directly adjacently arranged, providing a very compact while very efficient exhaust gas evaporator. | 12-23-2010 |
20120067557 | FLOW CHANNEL FOR A HEAT EXCHANGER, AND HEAT EXCHANGER COMPRISING SUCH FLOW CHANNELS - The invention relates to a flow channel of a heat exchanger with two parallel heat transfer areas (F | 03-22-2012 |
20130112382 | EXHAUST GAS EVAPORATOR - An evaporator, in particular an exhaust gas evaporator for an exhaust gas system of a motor vehicle, is provided that includes a plate sandwich structure having a plurality of fluid-guiding plate elements stacked on top of one another for guiding a first fluid, wherein at least one rib, in particular a corrugated rib, is disposed between two plate elements for guiding a second fluid, wherein a plate element comprises at least one cover element covering a flow channel and a flow channel plate unit, wherein the flow channel plate unit comprises at least one flow channel plate having flow channels in order to guide the first fluid from an inlet to an outlet. | 05-09-2013 |
20130125545 | SYSTEM FOR UTILIZING WASTE HEAT OF AN INTERNAL COMBUSTION ENGINE - A system for utilizing waste heat of an internal combustion engine via the Clausius-Rankine cycle process is provided that includes a circuit with lines containing a working medium, an evaporator heat exchanger which serves for evaporating the liquid working medium using waste heat of the internal combustion engine and which has an inlet opening for conducting the working medium into a flow duct and an outlet opening for conducting the working medium out of the flow duct, and the flow duct is divided into a plurality of flow duct parts connected hydraulically in parallel, an expansion machine, a condenser for liquefying the vaporous working medium, a collecting and compensating vessel for the liquid working medium, it is sought to be able to change the working medium substantially completely from a liquid state of aggregation to a gaseous state of aggregation at an evaporator heat exchanger. | 05-23-2013 |
20150052893 | HEAT EXCHANGER - A heat exchanger may include a gas conduit flowable through by a predetermined gas and a heat conduit flowable through by a predetermined fluid compound working fluid. The heat conduit may be in thermal communication with the gas conduit. The heat exchanger may include a first section having a first section length, a second section having a second section length, and a third section having a third section length. The gas conduit may span, in a direction of flow of the gas, the first section, the second section, and the third section. The heat conduit may span, in a direction of flow of the working fluid, the third section, the first section, and the second section. The first section may include a gas inlet and the third section may include a working fluid inlet and a gas outlet. The section may include a working fluid outlet. | 02-26-2015 |
Patent application number | Description | Published |
20100129405 | ISOLATION, CLONING AND CHARACTERIZATION OF NEW ADENO-ASSOCIATED VIRUS (AAV) SEROTYPES - The present invention provides new adeno-associated virus (AAV) viruses and vectors, and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the AAV vectors and particles. | 05-27-2010 |
20120253018 | Bovine Adeno-Associated Viral (BAAV) Vector and Uses Thereof - The present invention provides a bovine adeno-associated virus (BAAV) virus and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the BAAV vectors and particles. | 10-04-2012 |
20140024013 | Isolation, Cloning and Characterization of New Adeno-Associated Virus (AAV) Serotypes - The present invention provides new adeno-associated virus (AAV) viruses and vectors, and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the AAV vectors and particles. | 01-23-2014 |
20140221636 | Bovine Adeno-Associated Viral (BAAV) Vector and Uses Thereof - The present invention provides a bovine adeno-associated virus (BAAV) virus and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the BAAV vectors and particles. | 08-07-2014 |
20140296326 | EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) AND METHODS OF USE IN ADENOVIRAL-ASSOCIATED VIRUS TYPE 6 (AAV6) TRANSDUCTION - Comparative gene analysis (CGA) was combined with pathway visualization software to identify a positive correlation between AAV6 transduction and epidermal growth factor receptor (EGFR) expression. It was found that EGFR is necessary for vector internalization and functions as a co-receptor for AAV6. The identification and characterization of AAV6's requirement of EGFR expression for high transduction activity has allowed construction of recombinant AAV6 vectors which are capable of targeting and killing specific types of head and neck tumors that because of this high EGFR activity, were until now, refractory to current therapies. | 10-02-2014 |
Patent application number | Description | Published |
20110182230 | SYSTEMS AND METHOD FOR PROVIDING IN-FLIGHT BROADBAND MOBILE COMMUNICATION SERVICES - The invention relates to a ground-based wireless cellular communication system ( | 07-28-2011 |
20110287805 | TELECOMMUNICATION METHOD AND APPARATUS THEREOF - The invention relates to a telecommunication method in a base station of a mobile communication system, the mobile communication system comprising a plurality of base stations, a communication link being established between the base station and a user equipment, the method comprising the following steps performed by the base station: selecting one of the plurality of base stations as a target base station for a handover of the user equipment; transmitting a handover request to the target base station; receiving a handover request acknowledgement from the target base station, the handover request acknowledgment being indicative of at least one physical resource of the target base station; and transmitting a handover command to the user equipment via the communication link using the at least one physical resource. The handover command being descriptive of information required for accessing the target base station. | 11-24-2011 |
20120140760 | COMMUNICATIONS IN OFDMA-BASED WIRELESS RADIO NETWORKS - The invention relates to a method for transporting a machine-to-machine, M2M, signal ( | 06-07-2012 |
20120281672 | SYSTEM ARCHITECTURE FOR PROVIDING COMMUNICATIONS IN A WIRELESS COMMUNICATION NETWORK - Method for performing communications in a wireless communication network ( | 11-08-2012 |
20120315915 | METHOD FOR COMMUNICATING IN A WIRELESS COMMUNICATION NETWORK - The invention provides a method for communicating in a wireless communication network ( | 12-13-2012 |
Patent application number | Description | Published |
20110277906 | JOINING METHOD AND APPARATUS - The invention relates to a method for axial joining of a hybrid joining component to a workpiece, wherein the joining component has a thermoplastic joining section and a metal section which can be heated, having the following steps: moving the joining component into contact with a surface of the workpiece; heating of the metal section such that the joining section at least partially melts; ending the heating of the metal section such that the joining component makes a force-fitting, interlocking and/or integral connection with the surface of the workpiece. In this case, the joining component is held with a regulated force and/or in a regulated position with respect to the workpiece at least during the heating of the metal section, in such a manner that the joining component can be joined to the surface of the workpiece without any opposing support. | 11-17-2011 |
20110280650 | JOINING COMPONENT AND METHOD FOR PRODUCTION OF A JOINING COMPONENT - The present invention relates to a joining component for axial joining to a workpiece, having a base body composed of thermoplastic material which has a holding section and a flange section, with a joining surface being formed on the flange section and having a metal section which can be heated inductively. The metal section is in this case integrated in the flange section. | 11-17-2011 |
20130134153 | JOINING METHOD AND APPARATUS - A joining apparatus includes a joining tool on which a joining component is held and which moves the joining component in an axial direction to position a metal section of the joining component on a surface of the workpiece. A heating device is provided for heating the metal section of the joining component to integrally couple the metal section to the workpiece. A sensor is connected to the joining tool acting to determine a zero point defined when a joining surface of the metal section has reached the surface of the workpiece before the workpiece is axially deformed. | 05-30-2013 |
20140091495 | JOINING COMPONENT AND METHOD FOR PRODUCTION OF A JOINING COMPONENT - A method for production of a joining component, the method comprising the steps of providing a metal section which is inductively heatable and defines an axial through aperture; and coating the metal element with a thermoplastic material by a single-component injection-moulding of a base body of the joining component around the metal section so that the base body includes: a holding section formed as a cylindrical shaft and a flange, the flange including a first and second sides, and an inner side of the metal section is joined to the flange and an exposed outer side of the metal section faces away from the flange; and a the second side of the flange is axially recessed within the aperture; and a joining surface is comprised of the outer side of the metal section and a portion of the second side of the flange radially outward of the metal section. | 04-03-2014 |
Patent application number | Description | Published |
20120082498 | ELECTRICALLY-ASSISTED MECHANICAL BRAILLE WRITER - An electrically-assisted mechanical Braille writer includes a main solenoid to apply force to emboss Braille onto a printing medium, and advance an embossing mechanism to the next cell. A second solenoid engages a mechanical stop to prevent one or more embossing keys from being fully depressed, to prevent kickback from the keys mechanically coupling to the main solenoid. In unpowered operation, the mechanical stop is disengaged, and the embossing keys may be fully depressed to apply force to emboss Braille and advance the embossing mechanism. Accordingly, with electrical power, the user may supply a lesser amount of force and still fully emboss Braille cells, while without electrical power, the Braille writer remains fully operational. | 04-05-2012 |
20120082962 | BRAILLE ERASURE MECHANISM - An improved Braille erasure mechanism may comprise a reverse-embosser or impressing mechanism to imprint a negative Braille cell. A negative Braille cell is the reverse of a normal Braille cell, with one or more dots lowered or pressed into the printing medium in an opposite direction to the raised dots of a normal Braille cell. Because the dots of a negative Braille cell are lowered past the surface of the printing medium, they may be ordinarily undetectable to the fingers of a Braille user. Accordingly, by imprinting a full negative Braille cell on top of a Braille cell to be erased, all of the previously raised dots of the Braille cell may be lowered beyond the surface of the printing medium. Any further Braille cell embossed over the erased cell will be free from corruption, because any dot not used by the new cell will remain lowered and undetectable. | 04-05-2012 |
20140334861 | ELECTRICALLY-ASSISTED MECHANICAL BRAILLE WRITER - An electrically-assisted mechanical Braille writer includes a main solenoid to apply force to emboss Braille onto a printing medium, and advance an embossing mechanism to the next cell. A second solenoid engages a mechanical stop to prevent one or more embossing keys from being fully depressed, to prevent kickback from the keys mechanically coupling to the main solenoid. In unpowered operation, the mechanical stop is disengaged, and the embossing keys may be fully depressed to apply force to emboss Braille and advance the embossing mechanism. Accordingly, with electrical power, the user may supply a lesser amount of force and still fully emboss Braille cells, while without electrical power, the Braille writer remains fully operational. | 11-13-2014 |
Patent application number | Description | Published |
20120168323 | CASE FOR AN ELECTRONIC DEVICE HAVING A SCREEN - A case for use with an electronic device having a screen has a base and a support mechanism. The support mechanism has a flexible body that is movable relative to the base between a first (substantially flat) position and a second position. The flexible body is configured to bend into a convex configuration and extend in a direction away from the outer surface of the base in the second position. The body in the second position can be used to engage a flat surface and to support the electronic device in an at least partially vertical viewing position to display the screen on the electronic device. The support mechanism may include a single piece or two arms configured to move relative to each other. The support mechanism may move in a longitudinal or a lateral direction relative to the base. | 07-05-2012 |
20120168336 | CASE FOR AN ELECTRONIC DEVICE WITH A RESILIENT BAND FOR HOLDING ITEMS - Disclosed is a case or attachment device for use with an electronic device having a screen. The case has a base portion with a body having a back wall and side walls extending therefrom forming a receiving opening for receiving the electronic device. The case also includes a resilient band configured to hold one or more items (e.g., ID, credit cards, cash) against the case. The band may be pulled away from the body and items may be slid underneath the band so that they are held between an inner surface of the band and an outer surface of the body. The band may extend in a lateral, a longitudinal, or a diagonal direction. The band may also form a pocket for receiving items therein. The band can hold items against the back wall of the case. | 07-05-2012 |
20140221056 | ELECTRONIC DEVICE CASE WITH A FRICTION SURFACE - A case for use with an electronic device includes a base portion with side portions extending therefrom forming a pocket. The case also includes a first material generally at an exterior of the pocket, forming a majority of an exterior surface of the base portion, and a second material secured to and having a higher coefficient of friction than the first material, generally at an interior of the pocket. The second material protrudes through aperture(s) in the first material at the base portion to protrude from the interior to the exterior of the base portion, and outward from the first material such that the second material contacts a support surface when the base portion is placed thereon. The protruding second material extends away from the aperture(s) on opposing surfaces of the first material at the exterior and interior of the pocket to provide securement between the first and second materials. | 08-07-2014 |
Patent application number | Description | Published |
20130186747 | Glancing Angle Mill - A method and system for forming a planar cross-section view for an electron microscope. The method comprises directing an ion beam from an ion source toward a first surface of a sample to mill at least a portion of the sample; milling the first surface, using the ion beam, to expose a second surface in which the end of the second surface distal to the ion source is milled to a greater depth relative to a reference depth than the end of the first surface proximal to the ion source; directing an electron beam from an electron source to the second surface; and forming an image of the second surface by detecting the interaction of the electron beam with the second surface. Embodiments also include planarzing the first surface of the sample prior to forming a cross-section. | 07-25-2013 |
20130248354 | High Throughput TEM Preparation Processes and Hardware for Backside Thinning of Cross-Sectional View Lamella - A method for TEM sample preparation and analysis that can be used in a FIB-SEM system without re-welds, unloads, user handling of the lamella, or a motorized flip stage. The method allows a dual beam FIB-SEM system with a typical tilt stage to be used to extract a sample to from a substrate, mount the sample onto a TEM sample holder capable of tilting, thin the sample using FIB milling, and rotate the sample so that the sample face is perpendicular to an electron column for STEM imaging. | 09-26-2013 |
20140190934 | METHOD FOR PREPARING SAMPLES FOR IMAGING - A method and apparatus is provided for preparing samples for observation in a charged particle beam system in a manner that reduces or prevents artifacts. Material is deposited onto the sample using charged particle beam deposition just before or during the final milling, which results in an artifact-free surface. Embodiments are useful for preparing cross sections for SEM observation of samples having layers of materials of different hardnesses. Embodiments are useful for preparation of thin TEM samples. | 07-10-2014 |
20150214124 | Surface Delayering with a Programmed Manipulator - A method and apparatus for use in surface delayering for fault isolation and defect localization of a sample work piece is provided. More particularly, a method and apparatus for mechanically peeling of one or more layers from the sample in a rapid, controlled, and accurate manner is provided. A programmable actuator includes a delayering probe tip with a cutting edge that is shaped to quickly and accurately peel away a layer of material from a sample. The cutting face of the delayering probe tip is configured so that each peeling step peels away an area of material having a linear dimension substantially equal to the linear dimension of the delayering probe tip cutting face. The surface delayering may take place inside a vacuum chamber so that the target area of the sample can be observed in-situ with FIB/SEM imaging. | 07-30-2015 |
20150243477 | Bulk Deposition for Tilted Mill Protection - To reduce artifacts in a surface exposed by a focused ion beam for viewing, a trench is milled next to the region of interest, and the trench is filled to create a bulkhead. The ion beam is directed through the bulkhead to expose a portion of the region of interest for viewing. The trench is filled, for example, by charged particle beam-induced deposition. The trench is typically milled and filled from the top down, and then the ion beam is angled with respect to the sample surface to expose the region of interest. | 08-27-2015 |
20150243478 | High Aspect Ratio Structure Analysis - Curtaining artifacts on high aspect ratio features are reduced by reducing the distance between a protective layer and feature of interest. For example, the ion beam can mill at an angle to the work piece surface to create a sloped surface. A protective layer is deposited onto the sloped surface, and the ion beam mills through the protective layer to expose the feature of interest for analysis. The sloped mill positions the protective layer close to the feature of interest to reduce curtaining. | 08-27-2015 |
20150260784 | Multidimensional Structural Access - Multiple planes within the sample are exposed from a single perspective for contact by an electrical probe. The sample can be milled at a non-orthogonal angle to expose different layers as sloped surfaces. The sloped edges of multiple, parallel conductor planes provide access to the multiple levels from above. The planes can be accessed, for example, for contacting with an electrical probe for applying or sensing a voltage. The level of an exposed layer to be contacted can be identified, for example, by counting down the exposed layers from the sample surface, since the non-orthogonal mill makes all layers visible from above. Alternatively, the sample can be milled orthogonally to the surface, and then tilted and/or rotated to provide access to multiple levels of the device. The milling is preferably performed away from the region of interest, to provide electrical access to the region while minimizing damage to the region. | 09-17-2015 |
20150276567 | Method and System for Reducing Curtaining in Charged Particle Beam Sample Preparation - A method and system for exposing a portion of a structure in a sample for observation in a charged particle beam system, including extracting a sample from a bulk sample; determining an orientation of the sample that reduces curtaining; mounting the sample to a holder in the charged particle beam system so that the holder orients the sample in an orientation that reduces curtaining when the sample is milled to expose the structure; exposing the structure by milling the sample in a direction that reduces curtaining; and imaging the structure. | 10-01-2015 |
20150294834 | High Capacity TEM Grid - A TEM grid provides posts having steps, the steps increasing the number of samples that can be attached to the grid. In some embodiments, each post includes a one sided stair step configuration. A method of extracting multiple samples includes extracting samples and attaching the samples to the different stair steps on the posts. | 10-15-2015 |
20150330877 | METHOD FOR PREPARING SAMPLES FOR IMAGING - A method and apparatus is provided for preparing samples for observation in a charged particle beam system in a manner that reduces or prevents artifacts. An ion beam mills exposes a cross section of the work piece using a bulk mill process. A deposition precursor gas is directed to the sample surface while a small amount of material is removed from the exposed cross section face, the deposition precursor producing a more uniform cross section. Embodiments are useful for preparing cross sections for SEM observation of samples having layers of materials of different hardnesses. Embodiments are useful for preparation of thin TEM samples. | 11-19-2015 |
20150357159 | Fiducial Design for Tilted or Glancing Mill Operations with a Charged Particle Beam - A method for analyzing a sample with a charged particle beam including directing the beam toward the sample surface; milling the surface to expose a second surface in the sample in which the end of the second surface distal to ion source is milled to a greater depth relative to a reference depth than the end of the first surface proximal to ion source; directing the charged particle beam toward the second surface to form one or more images of the second surface; forming images of the cross sections of the multiple adjacent features of interest by detecting the interaction of the electron beam with the second surface; assembling the images of the cross section into a three-dimensional model of one or more of the features of interest. A method for forming an improved fiducial and determining the depth of an exposed feature in a nanoscale three-dimensional structure is presented. | 12-10-2015 |
Patent application number | Description | Published |
20140074829 | SYSTEMS AND METHOD FOR DATA SET SUBMISSION, SEARCHING, AND RETRIEVAL - Systems and methods of searching for related data sets are provided. Multivariate data sets can be input as queries into a data set search engine. According to one embodiment, the input data set is automatically reduced to a set of best fit data models of minimum complexity that represent the data set. The data model is then compared to other data models to not only identify similarity between the models, but also to identify the particulars of why the data models are related. The search engine can be configured to return sets of data models as results from the search on the input data set. Results can be organized on data model type and/or information scores. Results can also be displayed graphically as a topographical map of nodes and edge. Each node can represent a data model and each edge can reflect the similarity between the nodes. | 03-13-2014 |
20140172773 | SYSTEMS AND METHODS FOR SYMBOLIC ANALYSIS - Systems and methods of searching for related data sets are provided. Multivariate data sets can be input as queries into a data set search engine. According to one embodiment, the input data set is automatically reduced to a set of best fit data models of minimum complexity that represent the data set. The data model is then compared to other data models to not only identify similarity between the models, but also to identify the particulars of why the data models are related. Similar data model results can be analyzed to determine the quality of each returned data model based on an information scores. These results can be displayed graphically as a topographical map of nodes and edge. Each node can represent a data model and each edge can reflect the similarity between the nodes. | 06-19-2014 |
20140258189 | SYSTEM AND METHOD FOR AUTO-QUERY GENERATION - Various systems and methods provide an intuitive user interface that enables automatic specification of queries and constraints for analysis by ML component. Various implementations provide methodologies for automatically formulating machine learning (“ML”) and optimization queries. The automatic generation of ML and/or optimization queries can be configured to use examples to facilitate formulation of ML and optimization queries. One example method includes accepting input data specifying variables and data values associated with the variables. Within the input data any unspecified data records are identified, and a relationship between the variables specified in the input data and a variable associated with the at least one unspecified data record is automatically determined. The relationship can be automatically determined based on training data contained within the input data. Once a relationship is established a ML problem can be automatically generated. | 09-11-2014 |
Patent application number | Description | Published |
20140308267 | NEUROTOXINS EXHIBITING SHORTENED BIOLOGICAL ACTIVITY - The present invention relates to the pharmaceutical field. Specifically, it contemplates a polynucleotide encoding a neurotoxin polypeptide exhibiting a reduced duration of the biological effect in a subject, wherein said polypeptide comprises at least one E3 ligase recognition motif in the light chain, wherein said E3 ligase recognition motif is preferably a binding motif for the E3 ligase MDM2. The invention further pertains to polypeptides encoded by the polynucleotide of the invention as well as polypeptides comprising one or more amino acid substitutions. Further encompassed by the present invention are vectors and host cells comprising the said polynucleotide, polypeptides encoded thereby and antibodies specifically binding to the polypeptides. Moreover, the invention relates to medicaments comprising said polynucleotides and polypeptides, as well as specific therapeutic applications thereof. Furthermore, the present invention contemplates methods for the manufacture of the polypeptides and medicaments. | 10-16-2014 |
20150232828 | METHOD FOR THE MANUFACTURING OF RECOMBINANT PROTEINS HARBOURING AN N-TERMINAL LYSINE - This invention relates to a novel method for manufacturing and obtaining recombinant proteins, such as clostridial neurotoxins, harbouring an N-terminal lysine from precursor proteins. The method comprises the step of expressing a nucleic acid sequence encoding a precursor protein comprising an N-terminal motif, which can be recognised by an endoprotease specific for a lysine in P′1 position, and the step of cleaving the precursor protein with the endoprotease. The invention further relates to novel precursor proteins used in such methods, nucleic acid sequences encoding such precursor proteins and novel recombinant proteins, such as clostridial neurotoxins, harbouring an N-terminal lysine. | 08-20-2015 |
20150322118 | RECOMBINANT CLOSTRIDIAL NEUROTOXINS WITH ENHANCED MEMBRANE LOCALIZATION - This invention relates to novel recombinant clostridial neurotoxins exhibiting increased membrane localization and to methods for the manufacture of such recombinant clostridial neurotoxins. These methods comprise the steps of inserting a nucleic acid sequence coding for a C2 domain into a nucleic acid sequence coding for a parental clostridial neurotoxin and expression of the recombinant nucleic acid sequence comprising the C2 domain in a host cell. The invention further relates to novel recombinant single-chain precursor clostridial neurotoxins used in such methods, nucleic acid sequences encoding such recombinant single-chain precursor clostridial neurotoxins, and pharmaceutical compositions comprising the recombinant clostridial neurotoxin with increased membrane localization. | 11-12-2015 |