Patent application number | Description | Published |
20090076269 | PURINONE DERIVATIVES AS HM74A AGONISTS - The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease. | 03-19-2009 |
20090088446 | PURINONE DERIVATIVES AS HM74A AGONISTS - The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease. | 04-02-2009 |
20090124649 | AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLOPROTEASES - The present invention provides a compound of Formula I or Formula II: | 05-14-2009 |
20090286774 | PURINONE DERIVATIVES AS HM74A AGONISTS - The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease. | 11-19-2009 |
20090291946 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS - The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess. | 11-26-2009 |
20100137401 | 2-METHYLPROP ANAMIDES AND THEIR USE AS PHARMACEUTICALS - The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess. | 06-03-2010 |
20110136781 | IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS - The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. | 06-09-2011 |
20110288068 | AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLOPROTEASES - The present invention provides a compound of Formula I or Formula II: | 11-24-2011 |
20120035172 | Purinone Derivatives as HM74A Agonists - The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease. | 02-09-2012 |
20120122858 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS - The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess. | 05-17-2012 |
20130190315 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION - Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation. | 07-25-2013 |
20130190316 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION - Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation. | 07-25-2013 |
20130324515 | IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS - The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. | 12-05-2013 |
20140371216 | PURINONE DERIVATIVES AS HM74A AGONISTS - The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease. | 12-18-2014 |
20150344472 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION - Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation. | 12-03-2015 |
20150344483 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION - Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation. | 12-03-2015 |
Patent application number | Description | Published |
20140271591 | Compositions and methods for the modulation of hemoglobin (s) - This invention provides pharmaceutical compositions for the allosteric modulation of hemoglobin (S) and methods for their use in treating disorders mediated by hemoglobin (S) and disorders that would benefit from tissue and/or cellular oxygenation. | 09-18-2014 |
20140274961 | Compounds and uses thereof for the modulation of hemoglobin - Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation. | 09-18-2014 |
20140275152 | Compounds and uses thereof for the modulation of hemoglobin - Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation. | 09-18-2014 |
20140275176 | Compounds and uses thereof for the modulation of hemoglobin - Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation. | 09-18-2014 |
20150209443 | 1:1 ADDUCTS OF SICKLE HEMOGLOBIN - Provide herein are 1:1 adducts of sickle hemoglobin (HbS) and a compound of formula (I), as defined herein, suitable as modulators of HbS, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation. | 07-30-2015 |
20150315198 | PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS - In one aspect this invention relates generally to compounds of Formula: | 11-05-2015 |
20160024127 | COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN - Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation. | 01-28-2016 |
20160031865 | COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN - Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation. | 02-04-2016 |
20160031904 | COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN - Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation. | 02-04-2016 |
20160038474 | COMPOSITIONS AND METHODS FOR THE MODULATION OF HEMOGLOBIN (S) - This invention provides pharmaceutical compositions for the aliosteric modulation of hemoglobin (S) and methods for their use in treating disorders mediated by hemoglobin (S) and disorders that would benefit from tissue and/or cellular oxygenation. | 02-11-2016 |
Patent application number | Description | Published |
20090113619 | Dual spout-type faucet with controllable conventional-flow and mister-flow rates - A dual spout-type faucet with controllable conventional-flow and mister-flow rates is provided. In a first mode, one or more mister elements, or apertures having mister-like openings, are co-located proximate to a spout outlet, wherein water flow rates to the mister elements (or openings) and spout outlet are both controllable by one or more valve controllers accessible to a user. In a second mode, one or more mister elements, or apertures having mister-like openings, are co-axially located in a spout outlet wherein water flow rates to the mister elements (or openings) and spout outlet are both controllable by one or more valve controllers accessible to a user. In another embodiment the apparatus may be handheld and positionable and equipped to dispense soap or a cleaning solution optionally including attachable scrubbers. | 05-07-2009 |
20100241507 | System and method for searching, advertising, producing and displaying geographic territory-specific content in inter-operable co-located user-interface components - A network-based, integrated advertising and data searching system, and method for implementing the system, the system enhances the advertising exposure probability of transaction-enabling, associative discernible content ‘ADC’ elements proximately arranged on a website by storing, accessing and displaying transaction-enabling ADC element-related files in accordance with search criteria which matches geographic-territory specific data-files and optionally matches, category or subject data-files. The ADC element-related files are configurable for display in one or more groupings or word-cloud like arrangements within a single user interface or webpage, and in one embodiment, display one or more transactionable offerings, for a product, service or activity associated with at least one advertiser/seller according to user-specified criteria, or in response to input made via a user input device in communication with browser-equipped apparatus. The ADC elements are co-locatable with inter-operable, and selectable co-locatable software application tools ‘CSATs’, and with selectable search user interface elements. | 09-23-2010 |
Patent application number | Description | Published |
20120323689 | SYSTEMS AND METHODS FOR ADVERTISING AND MONETIZATION IN LOCATION BASED SPATIAL NETWORKS - A first request for a creation of a first social networking space is received. The first request comprises a first geospatial location and an identification of an advertisement, the advertisement being associated with an advertiser and a monetization fee. A social networking space is created based on the request. The social networking space comprises facilities for displaying the advertisement such that the advertisement is visible to users signed into the social networking space. A second request is received from a first user to sign into the first social networking space, such that the second request is transmitted from a mobile device associated with the first user. It is verified, using the computing device, that a current geospatial position of the mobile device is within the first geospatial location. In response to verifying the current geospatial position, the first user is signed into the first social networking space. A monetization event associated with the first social networking space is detected and the advertiser is charged, the monetization fee. | 12-20-2012 |
20120324018 | SYSTEMS AND METHODS FOR LOCATION BASED SOCIAL NETWORK - A first request for a creation of a social networking space is received, over a network, from a first user. The first request comprises a geospatial location, a start time, and an end time. A social networking space is creating, using a computing device, based on the request. The social networking space comprises facilities for posting messages visible to users signed into the social networking space. A second request is received, over the network, from second user to sign into the social networking space. The second request is transmitted from a mobile device associated with the second user. It is verified, using the computing device, that a first current time falls between the start time and the end time. It is further verified, using the computing device, that a first current geospatial position of the mobile device is within the geospatial location. In response to verifying the first current time and the first current geospatial position, the second user is signed into the social networking space. | 12-20-2012 |
20130117127 | CONTEXTUAL AD STORIES - In one embodiment, a set of advertisements may be identified based, at least in part, upon a profile of a user. The set of advertisements may include a plurality of advertisements, where each of the plurality of advertisements corresponds to a different one of a plurality of contexts. A context of the user may be ascertained. One of the plurality of advertisements may be selected based, at least in part, upon the context of the user. The selected one of the plurality of advertisements may be provided. | 05-09-2013 |
20130151602 | PERSONA ENGINE - In one embodiment at least one user profile of a user may be obtained. Information may be provided to the user by one or more personalization engines based, at least in part, upon the at least one user profile. Each of the one or more personalization engines may be configured to operate according to a different one of a plurality of personas. | 06-13-2013 |
20130159113 | GROUP PERSONALIZATION - In one embodiment, a group of two or more individuals may be identified. A set of one or more features of the group of two or more individuals may be ascertained. An item may be selected from a plurality of items based, at least in part, upon the set of one or more features of the group of two or more individuals. The item may be recommended or presented to at least a portion of the two or more individuals. | 06-20-2013 |
20130191215 | LOCATION-BASED APPLICATION POP UP - In one embodiment, a plurality of bids on a location are obtained, wherein each of the plurality of bids pertains to one of a plurality of applications. A pre-defined number of the plurality of applications are selected based, at least in part, upon the plurality of bids, such that a set of one or more of the plurality of applications is identified, wherein each of the plurality of bids pertains to an exclusive right for the set of one or more applications or one or more advertisements pertaining to the set of one or more applications to be provided to users present at the location. The set of one or more of the plurality of applications are associated with the location. | 07-25-2013 |
20130275218 | LOCATION-BASED WISH LIST - In one embodiment, the system obtains first information pertaining to one or more physical entities with respect to a user. The system creates or updates a profile pertaining to the user based, at least in part, upon the first information. The system provides second information to the user based, at least in part, upon the profile that has been created or updated. | 10-17-2013 |
20150026266 | SHARE TO STREAM - In one embodiment, a message transmitted from a first individual to a second individual via a communication platform may be identified, where the message includes a media item, a hypertext link providing access to the media item, or a Uniform Resource Locator (URL) providing access to the media item. The media item, hypertext link, or URL may be obtained from the message. The media item, hypertext link, or URL may be inserted into a stream associated with the second individual. The stream may be transmitted to the second individual via a media platform. | 01-22-2015 |
20150067505 | System And Methods For User Curated Media - Methods and systems for recommending online media content to other users includes receiving a selection of media content rendered on content page. The media content is identified by a user for sharing. A list of topics associated with the user is generated for presenting on a user interface. The topics are descriptive of the media content selected for sharing. Selection of one or more topics for the selected media content is received from the user. The received selections define the user's relevancy perspective for the selected media content. A recommendation for the selected media content is provided in content streams of users that follow the selected topics for users interactions with the selected media content. | 03-05-2015 |
20150135057 | Media Forums for Presenting and Managing User Generated Content Regarding Articles Presented on Websites - Methods, systems and computer readable media are provided for managing user generated content in relation to content. One example method includes receiving a request to access an article having descriptive content that includes one or more entities. Each entity in the article has an assigned prominence score, and the request is received from a website in response to user selection of the article. The method further includes identifying one or more media forums to relate to the article. Each media forum includes one or more discussion threads, and each media forum is associated with an interest graph that changes over time. Responsive to the request, the method selects a media forum from the one or more media forums to associate with the article based on examination of the interest graph of the media forum and the assigned prominence scores of entities in the article. The method presents the article on the website, wherein the presentation of the article includes additionally presenting the identified media forum in association with the article. | 05-14-2015 |
20150135058 | Media Forums for Managing Mobile Generated User Content and Associations to Articles - Methods, systems and computer readable media are provided for managing user generated content in relation to content. One example method includes receiving content from a mobile device. The received content is associated to one or more entities. The method associates the received content to a media forum. The association of the content to the media forum enabling at least one discussion regarding the received content on the media forum. The media forum having an interest graph that adjusts over time. Responsive to receiving a request to view an article, the method selects the media forum to be associated with the article when the article is presented on a display, the association of the media forum to the article provides an adjustment to the interest graph of the media forum. | 05-14-2015 |
Patent application number | Description | Published |
20120096018 | METHOD AND SYSTEM FOR SELECTING MUSIC - A method for selecting music and directing disposal thereof includes a step of providing a service with a database having music information stored therein and a user interface platform coupled to the database and accessible through a telecommunication device. A communication is received including a request for music from an external telecommunication device. An instruction is provided to the external telecommunication device for a song designator including one of a title, artist and/or lyric by one of voiced information, typed information, and a music source. The song designator is received from the external telecommunication device and the song designator is compared to music information stored in the database to determine the music requested. The telecommunication device is queried to determine a desired disposal of the requested music. The method can be performed with videos—search, upload, share, watch/listen. | 04-19-2012 |
20140088971 | System And Method For Voice Operated Communication Assistance - A system and method for voice operated communication assistance. Embodiments of the invention may include detecting a predetermined command from a first user making a call on a communication device; redirecting the call to a hosted application; and notifying the first user that the hosted application is ready to accept a command, receiving data from a second user; and converting the data from the second user to a voice signal and sending the voice signal to the first user. The commands may be a voice commands. | 03-27-2014 |
20140364083 | SYSTEM AND METHOD FOR VOICE OPERATED CALLING CARD - A voice operated calling card system and method. In one embodiment, there is provided a communications device, such as a mobile phone, for example, and a hosted application configured to accept voice commands and further configured to associate a user of the communications device with a calling card. The calling card may have funds associated with it. When a user places a call into the hosted application, the hosted application may allow the user of the communications device to purchase a service using the funds associated with the calling card, such as placing a long distance telephone call, for example. | 12-11-2014 |
20150012278 | SYSTEM AND METHOD FOR TRANSFERRING DATA TO A CUSTOMER RELATIONSHIP MANAGEMENT PLATFORM - A system and method for transferring data to a customer relationship management platform. A system for transferring data to a customer relationship management platform includes a server computer which is adapted to connect to a network and further includes an application residing on the server. The application may be configured to include the customer relationship platform. The application may also be configured to communicate with a communication device, such as a mobile phone, for example, through the network. The application may detect a voice command from a user using the communication device, then connect the user to the customer relationship management platform. The application may then take an action with the customer relationship management platform based on the voice command, such as making a sales call, populating the customer relationship management platform database with sales data or prospective customer data, or taking some administrative action. | 01-08-2015 |