Patent application number | Description | Published |
20120121613 | PROTEIN CONJUGATE HAVING AN ENDOPEPTIDASE- CLEAVABLE BIOPROTECTIVE MOIETY - The invention is directed to a procoagulant conjugate having an endopeptidase-activatable procoagulant protein moiety and one or more bioprotective moieties, which are conjugated to one another by a linker that is cleaved by an endopeptidase in situ to release the bioprotective moiety. The invention is also directed to therapeutic uses of the procoagulant conjugate and methods of making the conjugate. | 05-17-2012 |
20130017997 | Factor VIII Compositions and Methods of Making and Using Same - The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions. | 01-17-2013 |
20150038421 | FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions. | 02-05-2015 |
20150158929 | FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions. | 06-11-2015 |
Patent application number | Description | Published |
20110147259 | Stabilized Glycerin-in-Oil Emulsions - Compositions and methods are disclosed for stabilizing glycerin-in-oil emulsions, which can be used to significantly reduce thermal instability or instability over time compared to traditional cosmetics or topical formulations. The compositions comprise one or more oil-soluble rheological modifiers and optionally one or more emulsifiers in a glycerin-in-oil emulsion. | 06-23-2011 |
20120259252 | Coupling Emulsions for Use With Ultrasound Devices - Methods and cosmetic coupling compositions are provided that can be effectively used in conjunction with an ultrasound or similar device. The compositions and methods allow extended manipulation on the skin and heating without breaking down, pilling or balling and while maintaining a pleasant cosmetic feel and leaving skin feeling soft. | 10-11-2012 |
20130149358 | Wash Resistant Compositions Containing Aminosilicone - Compositions and methods are disclosed for imparting a long-wearing color to keratin fibers, including hair. More specifically, the invention relates to cosmetic compositions and methods for improving retention of particulate materials, such as pigments, on hair to artificially color the hair and/or to impart other aesthetic benefits to the hair. The compositions comprise at least one aminosilicone polymer having at least one diamino functional group, and a functional group equivalent weight (FGEW) from about 1,000 to about 2,000 g/mol and a non-spherical particulate material, preferably a pigment or a lake. | 06-13-2013 |
20130156714 | Long-Lasting Easy Wash-Off Cosmetic Compositions - Cosmetic compositions are provided, which are capable of forming a cosmetic film on a human integument when applied thereto. Cosmetic compositions according to the invention typically include a cosmetically acceptable vehicle, optionally, one or more colorants, and a pH-dependant film-forming polymer of poly(methacrylic acid-co-methyl methacrylate) having a ratio of methacrylic acid to methyl methacrylate of about 1:1 to about 1:2, an acid value of from about 150 to about 350 mg KOH/g, and a weight average molar mass between about 100,000 and about 150,000 g/mol. The compositions are capable of forming an adherent film on the integument that is substantially resistant to removal by water at a first pH, but readily dispersible or soluble in water at a second pH higher than said first pH. | 06-20-2013 |
20140044762 | Wash Resistant Compositions Containing Aminosilicone - Compositions and methods are disclosed for imparting a long-wearing color to keratin fibers, including hair. More specifically, the invention relates to cosmetic compositions and methods for improving retention of particulate materials, such as pigments, on hair to artificially color the hair and/or to impart other aesthetic benefits to the hair. The compositions comprise at least one aminosilicone polymer having at least one diamino functional group, and a functional group equivalent weight (FGEW) from about 1,000 to about 2,000 g/mol and a non-spherical | 02-13-2014 |
20140251361 | Long-Lasting Easy Wash-Off Cosmetic Compositions - Cosmetic compositions are provided, which are capable of forming a cosmetic film on a human integument when applied thereto. Cosmetic compositions according to the invention typically include a cosmetically acceptable vehicle, optionally, one or more colorants, and a pH-dependant film-forming polymer of poly(methacrylic acid-co-methyl methacrylate) having a ratio of methacrylic acid to methyl methacrylate of about | 09-11-2014 |
20150359730 | BASELLA ALBA EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-17-2015 |
20150359731 | PHYLLANTHUS ACIDUS EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-17-2015 |
20150359732 | VERNONIA CINEREA EXTRACTS AND METHODS OF USE - The present invention is directed to methods of using extracts of | 12-17-2015 |
20150366787 | SESBANIA ACULEATA EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-24-2015 |
20150366788 | CALOTROPIS GIGANTEA EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-24-2015 |
20150366789 | GLOCHIDIUM WALLICHIANUM EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-24-2015 |
20150366790 | PLUMERIA ACUMINATA EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-24-2015 |
20150366923 | ALLAMANDA CATHARTICA EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-24-2015 |
20150374617 | TETRACERA ASIATICA EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-31-2015 |
20150374618 | HEDYOTIS HEDROTIDEA EXTRACTS FOR COSMETICS - Methods of using extracts of Hedyotis hedyotidea to impart benefits to skin and/or improve skin conditions resulting from aging or damaged skin. | 12-31-2015 |
20150374619 | ABUTILON INDICUM EXTRACTS AND METHODS OF USE - Methods of using extracts of | 12-31-2015 |
Patent application number | Description | Published |
20120229230 | Impedance Transforming Coupler - A coupler circuit that includes two parallel coupled transmission lines (first transmission line and second transmission line) and a third transmission line, one end of the third transmission line connects to the end of first transmission line at one side, the other end of the third transmission line connects to the end of the second transmission line at the other side. Various coupling value and impedance transforming ratio can be achieved by select corresponding even and odd mode impedance of the coupled transmission lines and characteristic impedance of the crossing transmission line. | 09-13-2012 |
20130093534 | Doherty Power Amplifier Network - The present invention is directed to a network that includes an output matching network coupled to an amplifier. The output matching network is configured to transform the at least one amplifier transistor output impedance to an output matching network impedance. A combiner network is coupled to the output matching network. The combiner network includes a first quarter wavelength transmission line coupled between the in-phase signal path and a combiner node. The combiner network further includes a bandwidth enhancement element coupled to the quadrature signal path at the combiner node and an impedance transformation element coupled between the combiner node and a load. The impedance transformation element is configured to substantially transform a combined output matching network impedance at the combiner node to the load impedance. | 04-18-2013 |
20140085019 | SYMMETRICAL HYBRID COUPLER - The present invention is directed to a hybrid coupler device that includes a first transmission line structure and a second transmission line structure. The first transmission line structure is interdigitally coupled with the second transmission line structure such that each transmission line in the second transmission line structure is disposed adjacent to a transmission line in the first transmission line structure. The coupling or the mutual capacitance C | 03-27-2014 |
20140118071 | Compact Broadband Impedance Transformer - The present invention is directed to an impedance transformation device for use in a system having a characteristic system impedance, the device being characterized by a predetermined bandwidth having a center frequency. The device housing size is one-eighth wavelength of the center frequency. A first coupler is characterized by an even mode impedance and an odd mode impedance. The bandwidth is a function of the even mode impedance and the odd mode impedance substantially corresponds to the component port impedance. At least one second coupler is disposed in parallel with the first coupler and is characterized by the even mode impedance and the odd mode impedance. | 05-01-2014 |
20140253246 | WIDEBAND DOHERTY AMPLIFIER NETWORK - The present invention is directed to an amplifier system that includes a main amplifier configured to amplify and a peak amplifier that operates only in a high power mode. An impedance matching network is coupled to at least the peak power amplifier. An impedance transformation device is coupled to at least a portion of the impedance matching network. The impedance transformation device is configured as a balun in the high power mode. The balun includes a first input and second input coupled to the main amplifier and the peak amplifier respectively. The impedance transformation device is configured as an unbalanced line impedance transformer in the low power mode because the predetermined output impedance substantially grounds the second input. The Doherty device is characterized by an impedance transformation ratio of at least 4:1 and a relative bandwidth greater than or equal to 40%. | 09-11-2014 |
Patent application number | Description | Published |
20100288479 | Metal-Based Microchannel Heat Exchangers Made by Molding Replication and Assembly - Compression molding of metals is used to make microchannel heat exchangers. Heat transfer can be improved by employing controlled microchannel surface roughness. Flux-free bonding is achieved using a eutectic thin-film intermediate layer. Seals are leak-tight, mechanically strong, and uniform across multiple contact areas. The metal heat exchangers may be mass-produced inexpensively, and are useful for applications including the cooling of computer chips and other high-power electronic devices, air conditioning, refrigeration, condenser plates, radiators, fuel cell heat management, and instant water heating. | 11-18-2010 |
20110174040 | Continuous Microscale Forming of Metal-Based Microchannels and Other Microchannel Devices - A process is disclosed for producing metal-based, high-aspect-ratio microscale structures (HARMs), for example microchannels in a heat exchanger. The preferred manufacturing method operates in a continuous mode, and employs low-temperature rolling of metals. A process is disclosed for bonding metal microchannel sheets or plates to flat metal sheets or plates to form single-, double-, and multiple-layered microchannel structures. The process can operate at much lower temperatures than prior methods of compression microscale molding of metals, at room temperature or even lower. | 07-21-2011 |
Patent application number | Description | Published |
20080217241 | COMPOSITE FILTER MEDIA AND METHODS OF MANUFACTURE - A composite filter media structure is provided. In an exemplary embodiment, the composite filter media structure includes a corrugated base substrate that includes a nonwoven synthetic fabric formed by a dry-laid process that corrugates the base substrate during the forming process. The composite filter media structure also includes a nanofiber membrane deposited on at least one side of the base substrate by an electro-blown spinning process. | 09-11-2008 |
20080272048 | Filter cartridge media retention system - A filter cartridge comprises a pleat pack including filtration media for removing particulates from a particulate laden fluid stream moving in a first direction through the filtration media. The pleat pack is formed into a tubular configuration with a plurality of circumferentially spaced pleats. The filtration media is periodically subject to a cleaning fluid stream moving in a second direction opposite to the first direction. Potting material is at axially opposite end portions of the pleat pack to maintain the filtration media in the tubular configuration. A support tube is located on a first side of the pleat pack downstream of the filtration media in the first direction of fluid flow. A retention device limits movement of a portion of the filtration media when subjected to the periodic cleaning fluid stream. The retention device comprises a metal band and located on a second side of the filtration media opposite the first side. A rod is disposed in the potting material of at least one of the axial end portions of the pleat pack. The rod is fixed to the metal band to maintain the metal band in an axial position along the filtration media. | 11-06-2008 |
20080314011 | FILTER ELEMENT INCLUDING A COMPOSITE FILTER MEDIA - A filter element includes, in an exemplary embodiment, a first end cap, a second end cap, and a composite filter media structure. The composite filter media structure includes a base substrate that includes a nonwoven synthetic fabric formed from a plurality of bicomponent synthetic fibers with a spunbond process, and having a bond area pattern having a plurality of substantially parallel discontinuous lines of bond area. The base substrate having a minimum filtration efficiency of about 50%, measured in accordance with ASHRAE 52.2-1999 test procedure. The composite filter media structure also includes a nanofiber layer deposited on one side of the base substrate by an by electro-blown spinning process. The composite filter media structure having a minimum filtration efficiency of about 75%, measured in accordance with ASHRAE 52.2-1999 test procedure. The composite media structure further includes a plurality of corrugations formed at a temperature of about 90° C. to about 140° C. | 12-25-2008 |
20100126130 | FILTER ELEMENT WITH HIGH TEMPERATURE POLYMER RETAINING STRAPS AND METHOD OF MANUFACTURE - A filter element for removing particles from a particulate laden fluid stream includes, in an exemplary embodiment, a filtration media formed into a tubular configuration and that a plurality of circumferentially spaced apart pleats. The filter element also includes at least one melt-extruded retention strap extending circumferentially around the filtration media to limit radial movement of the filtration media at operating temperatures up to about 500° F. Each melt-extruded retention strap is formed from a melt extrudable amorphous thermoplastic polyimide. | 05-27-2010 |
20110252757 | HELICAL STRAPPING METHOD FOR HIGH TEMP PLEATED FILTERS - A filter cartridge that includes a filter media. The media is pleated and the pleats are arranged into a tube about an axis with a first pleat proximate a last pleat. The filter cartridge includes a strap that has first and second end portions and that extends at least one revolution around the pleated media tube in a helix such that the first and second end portions of the strap are axially displaced from each other. The first and last pleats of the media are attached to each other and the first and second end portions of the strap are attached to the media. The filter cartridge may be made by an associated method. In one specific example, a stitching attaches the strap to the media. | 10-20-2011 |
20120012518 | CORELESS FILTER CARTRIDGE AND METHOD OF FORMING A CORELESS FILTER CARTRIDGE - A coreless filter cartridge includes a filtration media having a plurality of pleats formed in a tubular configuration. The filtration media includes a first end that extends to a second end through an intermediate portion having an exterior surface and an interior surface that defines a hollow core. At least one retention device is adhered to the exterior surface of the filtration media. The at least one retention device is configured and disposed to limit radial movement of the filtration media. The filter cartridge is devoid of an internal core support provided within the hollow core thereby establishing a coreless filter cartridge. | 01-19-2012 |
20120324845 | FILTER ASSEMBLY FOR USE IN A BAGHOUSE - A filtration system is provided. The filtration system includes a flexible attachment portion, the attachment portion configured to couple the bag filter to a tube sheet, an adapter ring attached to the attachment portion, and a bag filter attached to the adapter ring. | 12-27-2012 |
20130042585 | FILTER CORE FOR USE WITH PLEATED FILTER CARTRIDGES - A filter core includes a tubular body that has a first end and a second end. The tubular body includes a plurality of surface features spaced longitudinally along the tubular body between the first and second ends. Each of the surface features includes a first portion for flow area and a second portion for bridging across an opening for strength. | 02-21-2013 |
Patent application number | Description | Published |
20100184863 | SYNTHETIC SPILANTHOL AND USE THEREOF - The present application provides a synthetic spilanthol flavor composition that includes (2E,6Z,8E)-N-(2-methylpropyl)-2,6,8-decatrienamide. The synthetic spilanthol composition can also contain, and at least one of (2E, 6E, 8E)-N-(2-methylpropyl)-2,6,8-decatrienamide and (2E, 6Z, 8Z)-N-(2-methylpropyl)-2,6,8-decatrienamide, the (N-(2-methylpropyl)-2,6,8-decatrienamide being present in amounts effective to impart a salivating or tingle effect while reducing the perception of off notes, as compared to the off-notes perceived upon consumption of natural spilanthol (e.g. spilanthol obtained from jambu oleoresin). Methods of increasing salivation and/or providing a tingling sensation upon consuming an orally consumable product that include adding to the product a synthetic spilanthol flavor composition are also provided. Synthetic spilanthol flavor compositions can be added to orally consumed products, such as, but not limited to, foods, beverages, pharmaceuticals, nutraceuticals, or therapeutic compositions, oral personal care products, gums (e.g. chewing gum or bubble gum), candy or lozenges. | 07-22-2010 |
Patent application number | Description | Published |
20110288253 | MULTI-COLORED CONJUGATED POLYMERS WITH HIGHLY TRANSMISSIVE OXIDIZED STATE - Embodiments of the invention are directed to random conjugated copolymers comprising a plurality of one or more different donor (D) repeating units and a plurality of at least one acceptor (A) repeating unit. At least one of the D units has a solubilizing substituent, statistically a portion of the A repeating units are separated from each other by only one D units and a plurality of the A unit are adjacent to one the D units having the solubilizing substituents. The random conjugated copolymers are black or colored in the neutral state and highly transmissive in the oxidized state. The random conjugated copolymers have the structure -[(D) | 11-24-2011 |
20130126836 | HIGH-MOBILITY STRUCTURES, APPARATUSES AND METHODS THEREFOR - Various apparatuses, systems and methods involve high mobility materials. In accordance with one or more example embodiments, a material includes a conjugated molecule and a side chain bonded to the conjugated molecule. The side chain includes at least one of a siloxane-terminated unit and a derivative of a siloxane-terminated unit that enhance solubility of the conjugated molecule. Further, the side chain facilitates a π-stacking distance between the conjugated molecules when stacked (e.g., in an organic semiconductor film), thereby facilitating carrier mobility between the conjugated molecules | 05-23-2013 |
20150105520 | CONJUGATED POLYMER-BASED APPARATUSES, ARTICLES AND COMPOUNDS - Various aspects of the present disclosure are directed to conjugated polymers, their manufacture and their implementations. As may be implemented in connection with one or more embodiments, an apparatus includes a conjugated polymer and a side chain or end chain material connected to the conjugated polymer. The amount and makeup of the side chain or end chain enhance solubility of the resulting modified conjugated polymer, relative to the conjugated polymer itself. | 04-16-2015 |
Patent application number | Description | Published |
20100136004 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS - Methods and compositions for modulating GABA release in a subject are provided. A preferred embodiment provides a composition containing an effective amount of an ErbB4 ligand to enhance or promote GABA release, i.e., GABAergic transmission. The ErbB4 ligand can be an agonist ligand or an antagonist ligand depending on the disorder to be treated. Methods for treating neurological disorders are also provided. Representative disorders that can be treated include, but are not limited to schizophrenia, epilepsy, depression and anxiety, insomnia, stroke, pain, bipolar, autism, or a combination thereof. By increasing GABA release a sedative effective can be induced in the subject. Methods for inducing a stimulatory effect in a subject are also provided. In these methods, an effective amount of an ErbB4 antagonist ligand is administered to the subject to reduce or inhibit GABA release in the subject. | 06-03-2010 |
20100260774 | Netrin-1 Compositions and Methods of Use Thereof - Methods and compositions for male or female contraception are provided. The compositions include an effective amount of netrin-1 to reduce or inhibit sperm concentration in semen of males or to inhibit or reduce fusion of male gametes with female gametes in a female subject Still another embodiment provides a method for diagnosing male infertility by determining the amount of netrin-1 in a sample of epididymal fluid or semen from a male subject, comparing the amount of netting-1 in the sample to levels of netrin-1 in samples of epididymal fluid or semen from fertile males, wherein levels of netrin-1 in the sample from the male subject that are higher or lower than levels of netrin-1 in samples from fertile males are indicative of male infertility in the male subject. | 10-14-2010 |
20100291077 | Methods and Compositions for Modulating ERBB2 Activity - Modulating the interaction between ErbB2 and Erbin is an effective method for treating one or more symptoms of ErbB2-mediated disorders. It has been discovered that Erbin stabilizes ErbB2 in vivo and inhibiting the formation of heterodimers between Erbin and ErbB2 reduces or inhibits the biological activity of ErbB2 relative to control levels. Reducing the biological activity of ErbB2 is useful in the treatment of conditions characterized by the overexpression or misregulation of ErbB2. These conditions include, but are not limited to breast cancer and prostate cancer. Alternatively, agonist of Erbin that promote or enhance the interaction of Erbin with ErbB2 can be useful in the treatment of certain neurological disorders. It has also been discovered that Erbin plays a role in the myelination of neurons of the peripheral nervous system. | 11-18-2010 |
20120039881 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS - Methods and compositions for modulating GABA release in a subject are provided. A preferred embodiment provides a composition containing an effective amount of an ErbB4 ligand to enhance or promote GABA release, i.e., GABAergic transmission. The ErbB4 ligand can be an agonist ligand or an antagonist ligand depending on the disorder to be treated. Methods for treating neurological disorders are also provided. Representative disorders that can be treated include, but are not limited to schizophrenia, epilepsy, depression and anxiety, insomnia, stroke, pain, bipolar, autism, or a combination thereof. By increasing GABA release a sedative effective can be induced in the subject. Methods for inducing a stimulatory effect in a subject are also provided. In these methods, an effective amount of an ErbB4 antagonist ligand is administered to the subject to reduce or inhibit GABA release in the subject. | 02-16-2012 |
20130108616 | DETECTION AND TREATMENT OF LRP4-ASSOCIATED NEUROTRANSMISSION DISORDERS | 05-02-2013 |
20130224223 | Compositions and Methods for Treating Neurological Disorders - Methods and compositions for modulating GABA release in a subject are provided. A preferred embodiment provides a composition containing an effective amount of an ErbB4 ligand to enhance or promote GABA release, i.e., GABAergic transmission. The ErbB4 ligand can be an agonist ligand or an antagonist ligand depending on the disorder to be treated. Methods for treating neurological disorders are also provided. Representative disorders that can be treated include, but are not limited to schizophrenia, epilepsy, depression and anxiety, insomnia, stroke, pain, bipolar, autism, or a combination thereof. By increasing GABA release a sedative effective can be induced in the subject. Methods for inducing a stimulatory effect in a subject are also provided. In these methods, an effective amount of an ErbB4 antagonist ligand is administered to the subject to reduce or inhibit GABA release in the subject. | 08-29-2013 |
20140243268 | ERBB2 Peptides - Compositions that inhibit or block the interaction between Erbin and ErbB2 and methods of their use are provided. Preferred compositions include peptides that inhibit or block Erbin and ErbB2 interaction under physiologic conditions in a subject. One embodiment provides an isolated peptide fragment of ErbB2 including the C-terminal 15 amino acids of ErbB2. The peptide fragment can be about 15 to 27 amino acids in length. | 08-28-2014 |
Patent application number | Description | Published |
20090066368 | DIGITAL CALIBRATION CIRCUITS, DEVICES AND SYSTEMS INCLUDING SAME, AND METHODS OF OPERATION - A calibration circuit for matching the output impedance of a driver by calibrating adjustments to the driver is described. The calibration circuit includes a driver circuit with a plurality of calibration transistors configured to receive a plurality of adjustment signals. The calibration circuit also includes a comparator circuit, and a binary searcher. The driver provides a signal corresponding to an output impedance to the comparator circuit. The output impedance signal is compared to a target impedance, and the comparator circuit then provides logic signals to the binary searcher representing whether the output impedance is greater than the target impedance. The binary searcher then selects a type of step size and count direction, in response to the logic signals, to count the number of steps for adjusting the calibration transistors of the driver. | 03-12-2009 |
20090153253 | SYSTEM AND METHOD FOR REDUCING LOCK TIME IN A PHASE-LOCKED LOOP - Increasing loop gain is a common practice for reducing lock time of phase locked loops. Very high loop gains, however, often result in increasing the lock time or causing loop instability. For very high loop gains, delaying the feedback clock signal along the feedback path of a phase locked loop decreases lock time and prevents instability. A delay circuit may be used at any location along the feedback path of the phase locked loop. | 06-18-2009 |
20100182057 | LOCKED LOOPS, BIAS GENERATORS, CHARGE PUMPS AND METHODS FOR GENERATING CONTROL VOLTAGES - Locked loops, bias generators, charge pumps and methods for generating control voltages are disclosed, such as a bias generator that generates bias voltages for use by a clock signal generator, such as a voltage controlled delay line, in a locked loop having a phase detector and a charge pump. The charge pump can either charge or discharge a capacitor as a function of a signal from the phase detector to generate a control voltage. The bias generator can receive the control voltage from the capacitor, and it generates bias voltages corresponding thereto. A portion of the bias generator can have a topography that is substantially the same as at least a portion of the topography of the charge pump. As a result, it can cause the charge pump to charge the capacitor at the same rate that it discharges the capacitor over a relatively wide range of control voltages. The charge pump and the bias generator can also include circuitry for limiting the charging of the capacitor when the control voltage is relatively low. | 07-22-2010 |
20110012655 | LOCKED LOOPS, BIAS GENERATORS, CHARGE PUMPS AND METHODS FOR GENERATING CONTROL VOLTAGES - Locked loops, bias generators, charge pumps and methods for generating control voltages are disclosed, such as a bias generator that generates bias voltages for use by a clock signal generator, such as a voltage controlled delay line, in a locked loop having a phase detector and a charge pump. The charge pump can either charge or discharge a capacitor as a function of a signal from the phase detector to generate a control voltage. The bias generator can receive the control voltage from the capacitor, and it generates bias voltages corresponding thereto. A portion of the bias generator can have a topography that is substantially the same as at least a portion of the topography of the charge pump. As a result, it can cause the charge pump to charge the capacitor at the same rate that it discharges the capacitor over a relatively wide range of control voltages. The charge pump and the bias generator can also include circuitry for limiting the charging of the capacitor when the control voltage is relatively low. | 01-20-2011 |
20110148493 | OUTPUT SLEW RATE CONTROL - This document discusses, among other things, output slew rate control. Methods and structures are described to provide slew rate control of an output driver circuit such as a DRAM output driver on a die. A selectable combination of series coupled transistors are configured as a parallel array of complementary inverter pairs to provide a divided voltage to a calibrator. The calibrator is configured to respond to a differential voltage to adjust the divided voltage such that the differential voltage is forced to zero. The calibrator outputs a plurality of discrete signals from an up/down counter to switch on and off the individual transistors of the parallel array to increase and decrease a collective current. In some embodiments, transistor channel currents are modulated to step-adjust a voltage based on a ratio associated with a static resistance. In various embodiments, the divided voltage is an analog voltage based on a resistance associated with trim circuitry. | 06-23-2011 |
20110234324 | SYSTEM AND METHOD FOR REDUCING LOCK TIME IN A PHASE-LOCKED LOOP - Increasing loop gain is a common practice for reducing lock time of phase locked loops. Very high loop gains, however, often result in increasing the lock time or causing loop instability. For very high loop gains, delaying the feedback clock signal along the feedback path of a phase locked loop decreases lock time and prevents instability. A delay circuit may be used at any location along the feedback path of the phase locked loop. | 09-29-2011 |
20120169381 | OUTPUT SLEW RATE CONTROL - This document discusses, among other things, output slew rate control. Methods and structures are described to provide slew rate control of an output driver circuit such as a DRAM output driver on a die. A selectable combination of series coupled transistors are configured as a parallel array of complementary inverter pairs to provide a divided voltage to a calibrator. The calibrator is configured to respond to a differential voltage to adjust the divided voltage such that the differential voltage is forced to zero. The calibrator outputs a plurality of discrete signals from an up/down counter to toggle the individual transistors of the parallel array to increase and decrease a collective current. In some embodiments, transistor channel currents are modulated to step-adjust a voltage based on a ratio associated with a static resistance. In various embodiments, the divided voltage is an analog voltage based on a resistance associated with trim circuitry. | 07-05-2012 |
20120200341 | LOCKED LOOPS, BIAS GENERATORS, CHARGE PUMPS AND METHODS FOR GENERATING CONTROL VOLTAGES - Locked loops, bias generators, charge pumps and methods for generating control voltages are disclosed, such as a bias generator that generates bias voltages for use by a clock signal generator, such as a voltage controlled delay line, in a locked loop having a phase detector and a charge pump. The charge pump can either charge or discharge a capacitor as a function of a signal from the phase detector to generate a control voltage. The bias generator can receive the control voltage from the capacitor, and it generates bias voltages corresponding thereto. A portion of the bias generator can have a topography that is substantially the same as at least a portion of the topography of the charge pump. As a result, it can cause the charge pump to charge the capacitor at the same rate that it discharges the capacitor over a relatively wide range of control voltages. | 08-09-2012 |
Patent application number | Description | Published |
20130059835 | HETEROCYCLYLAMINES AS PI3K INHIBITORS - The present invention provides heterocyclylamine derivatives of Formula I: | 03-07-2013 |
20140057912 | PYRIMIDINE-4,6-DIAMINE DERIVATIVES AS PI3K INHIBITORS - The present invention provides pyrimidine-4,6-diamine derivatives of Formula (I): wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases. | 02-27-2014 |
20140066448 | SUBSTITUTED DIAMINO-PYRIMIDINE AND DIAMINO-PYRIDINE DERIVATIVES AS PI3K INHIBITORS - The present invention provides substituted diamino-pyrimidine and substituted diamino-pyridine derivatives of Formula I; wherein X, Y, R | 03-06-2014 |
20140121198 | TRICYCLIC FUSED THIOPHENE DERIVATIVES AS JAK INHIBITORS - The present invention provides tricyclic fused thiophene derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase (JAK) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases. | 05-01-2014 |
20140249132 | USE OF PYRAZOLOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PI3K-DELTA RELATED DISORDERS - The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I: | 09-04-2014 |
20140343030 | BIPYRAZOLE DERIVATIVES AS JAK INHIBITORS - The present invention provides compounds of Formula I: | 11-20-2014 |
20150057265 | FURO- AND THIENO-PYRIDINE CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS - The present disclosure describes furo- and thieno-pyridine carboxamide compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases. | 02-26-2015 |