Mauro, US
Anthony Mauro, San Diego, CA US
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20120316869 | GENERATING A MASKING SIGNAL ON AN ELECTRONIC DEVICE - An electronic device for generating a masking signal is described. The electronic device includes a plurality of microphones and a speaker. The electronic device also includes a processor and executable instructions stored in memory that is in electronic communication with the processor. The electronic device obtains a plurality of audio signals from the plurality of microphones. The electronic device also obtains an ambience signal based on the plurality of audio signals. The electronic device further determines an ambience feature based on the ambience signal. Additionally, the electronic device obtains a voice signal based on the plurality of audio signals. The electronic device also determines a voice feature based on the voice signal. The electronic device additionally generates a masking signal based on the voice feature and the ambience feature. The electronic device further outputs the masking signal using the speaker. | 12-13-2012 |
Anthony J. Mauro, Assonet, MA US
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20090084575 | Indicia-Marked Electrical Cable - An electrical cable includes a sheath that envelops at least two internal conductors, and an indicia visible on the sheath is representative of the internal conductor. | 04-02-2009 |
20130000942 | INDICA-MARKED ELECTRICAL CABLE - An electrical cable includes a sheath that envelops at least two internal conductors, and an indicia visible on the sheath is representative of the internal conductor. | 01-03-2013 |
Daniel E. Mauro, Norwalk, IA US
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20090264226 | BASKETBALL HOOP ASSEMBLY - A basketball hoop assembly and kit is described with the assembly comprising a flexible sheet which has the shape of a backboard, a hoop mount which is secured to the front face of the sheet, a hoop which is secured to the hoop mount and a net which is secured to the hoop. The basketball hoop assembly of this invention may be mounted on a wall surface by means of the adhesive backing on the sheet and may be removed therefrom without leaving marks on the wall or residue thereon. | 10-22-2009 |
David Mauro, Dolton, IL US
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20110178288 | PROCESS FOR THE PRODUCTION OF MALTODEXTRINS AND MALTODEXTRINS - There is disclosed a process for preparing liquid maltodextrin having a D.E. of about 5 to less than about 20. Also disclosed are liquid maltodextrins having a D.E. of about 9 to about 15. | 07-21-2011 |
David J. Mauro, Washington Crossing, PA US
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20160022814 | COMBINATION OF A PD-1 ANTAGONIST AND A LISTERIA-BASED VACCINE FOR TREATING PROSTATE CANCER - The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a | 01-28-2016 |
David J. Mauro, Princeton, NJ US
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20120270228 | PREDICTORS OF PATIENT RESPONSE TO TREATMENT WITH EGF RECEPTOR INHIBITORS - The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness. | 10-25-2012 |
David J. Mauro, Redwood City, CA US
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20090298701 | PREDICTORS OF PATIENT RESPONSE TO TREATMENT WITH EGF RECEPTOR INHIBITORS - The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness. | 12-03-2009 |
David J. Mauro, Dolton, IL US
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20110052780 | PREPARATION OF ENZYMATICALLY HYDROLYZED STARCH - The present invention pertains to methods for preparing enzymatically hydrolyzed starch for use as a stabilizing agent that include the steps of first gelatinizing a starch and next, hydrolyzing the gelatinized starch with an enzyme having endo-hydrolytic activity. The present invention also pertains to the resulting enzymatically hydrolyzed starch for use as a stabilizing agent within emulsions, beverages, food products and industrial products prepared using the enzymatically hydrolyzed starch. | 03-03-2011 |
20140343273 | PREPARATION OF ENZYMATICALLY HYDROLYZED STARCH - The present invention pertains to methods for preparing enzymatically hydrolyzed starch for use as a stabilizing agent that include the steps of first gelatinizing a starch and next, hydrolyzing the gelatinized starch with an enzyme having endo-hydrolytic activity. The present invention also pertains to the resulting enzymatically hydrolyzed starch for use as a stabilizing agent within emulsions, beverages, food products and industrial products prepared using the enzymatically hydrolyzed starch. | 11-20-2014 |
Derek Mauro, Scarsdale, NY US
Patent application number | Description | Published |
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20130144836 | CANONICALIZATION OF UNIFORM RESOURCE IDENTIFIERS - One or more server devices may obtain a stored resource identifier associated with a resource identifier collection. The one or more server devices may further access a document index that stores information about canonical resource identifiers, where the information relates a particular canonical resource identifier to one or more other resource identifiers; determine whether the canonical resource identifier differs from the stored resource identifier; and replace the stored resource identifier with the canonical resource identifier, when the canonical resource identifier differs from the stored resource identifier. | 06-06-2013 |
Ed Mauro, Palm Harbor, FL US
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20150033623 | ADJUSTABLE PLANT SUPPORT - An adjustable plant support is disclosed. The support includes an upright support, a plurality of holes disposed along a length of the upright support, and at least one support arm configured to be removably secured to the upright support through a selected hole of the plurality of holes. The support arm also includes a hook at a distal end of the support arm and is configured to define an interior portion of the support arm and adapted to support a plant. A pin of the support arm is at a proximate end of the support arm, where a free end of the pin is configured to slidingly engage the selected hole. In addition, the pin of the support arm extends back towards the U-shape collar in a different lateral plane, where a width of the U-shaped collar is configured to slidingly engage an outer surface of the upright support. | 02-05-2015 |
20160001639 | UNIVERSAL GOLF CART WINDSHIELD ASSEMBLY - A universal golf cart windshield assembly includes a pair of elongated rails and a bracket secured to each rail, where each bracket is configured to clamp over a vertical support member of a golf cart. A longitudinal slot is disposed on each rail and a flange is joined along a longitudinal edge of the longitudinal slot and extends generally at a right angle to the slot. A plurality of apertures are disposed on the flange of each rail. The assembly also includes a lower windshield pane and an upper windshield pane, where opposing edges of the upper windshield pane are slidingly engaged with the respective longitudinal slot of each rail. In addition, the assembly also includes a spring loaded latch secured to the upper windshield pane, where the pin is adapted to engage a desired aperture of the flange to restrain the upper windshield pane in a desired vertical position. | 01-07-2016 |
Eric Mauro, Boca Raton, FL US
Patent application number | Description | Published |
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20100039248 | Vehicle window position indicator - A device for installation in an automobile including a passenger car, minivan or bus (e.g., a school bus) indicates the position of each window and emergency exit of the vehicle and sounds an alarm to indicate to the driver of the vehicle that one or more of the windows and/or emergency exits is open. The alarm may be a combination of a visual lighted display on the driver console and/or an audible alarm indicator. The visual indicator may further indicate the operative position of any particular window or emergency door opening between the closed position, slight open, half open and fully open positions. The device alerts the driver of the vehicle to correct the window position of each window and emergency exit of the vehicle for purposes of safety as well as to prevent robbery and/or damage to the vehicle (e.g., from rain, sprinklers, etc.) when leaving the vehicle unoccupied. The device may also alert the driver to crack the windows partially open when leaving a pet in the vehicle for a short time. | 02-18-2010 |
20100040403 | Ornamental articles and devices for attachment to writting instruments - Ornamental articles and devices such as, but not limited to, charms, flags, animated characters, flashlights, magnifying glasses, and gas pump speed pay devices clipped to or otherwise attached to a writing instrument, such as a pen. In a preferred embodiment, the ornamental articles and other devices clip to the top of the writing instrument. In a further embodiment, the ornamental articles and devices attach to the pocket clip of a writing instrument and are visibly displayed when the writing instrument is carried in a pocket of an article of clothing. | 02-18-2010 |
Gary M. Mauro, Astoria, OR US
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20140366892 | Mouthguard Configured for Attachment to a Chin Strap - A mouth guard configured for attachment to a portion of a chin strap assembly. Rather than attaching to the facemask, the invention is configured to attach to a portion of the chin strap and preferably to attach to the molded chin cup that is now part of most chin strap assemblies. The mouth guard includes a stem extending forward from the portion intended to be clenched between the teeth. This stem is used to attach the mouth guard to a portion of the chin strap assembly. Preferably, the connection is made in two stages. First, the stem is attached to a separate lip guard. Second, the lip guard is attached to the chin cup (a portion of the chin strap assembly). | 12-18-2014 |
George Mauro, Salem, NH US
Patent application number | Description | Published |
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20110317951 | INTEGRATED BEARING ASSEMBLY - An integrated bearing assembly comprising first and second cylindrical members radially spaced apart from one another along an axis of rotation. The first cylindrical member supports a first portion of a first bearing track while the second cylindrical member supports a second portion of the first bearing track. The first and the second portions face one another and a plurality of bearing elements are retained therein to facilitate relative rotation. At least one of the first and second portions comprises a pair of adjacent V-shaped bearing surfaces. One of the first and the second cylindrical members supports a retaining element which has a bearing surface that forms at least a portion of one of the first and second portions of the first bearing track. The retaining element is adjustable, in a direction parallel to the axis of rotation, to adjust a pressure to be applied to the plurality of captively retained bearings. | 12-29-2011 |
George Edward Mauro, Salem, NH US
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20100162580 | GONIOMETER - A goniometer including an arcuate rotor plate rotatable about an axis of motion spaced apart from the rotor plate for supporting a device and a base having an arcuate base plate The rotor is rotationally coupled to the base by shaft and a resilient shaft bearing mounting exerting a resilient force on the shaft to maintain a positive engagement between the roller and rotor body. | 07-01-2010 |
Giovanni Mauro, Washington Township, MI US
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20120045314 | Road With Inlayed Wind Harnessing Technology - A method and apparatus is provided for harnessing the wind energy generated by vehicles passing on a roadway. A roadway is provided with a trench extending from a surface of the roadway. The trench may be provided along an extended stretch of the roadway or as a discrete trench section spaced apart along the roadway. The trench or trench section may be provided near the middle of a lane making up the roadway such that a vehicle travelling on the roadway passes over the trench. In this manner the wind displaced by the passing vehicle is directed into the trench and experienced by a wind turbine or wind generator provided within the trench. The trench is covered by a structure configured to direct the displaced wind inside the trench. The wind turbine converts the kinetic energy of the wind into mechanical energy that is then converted into useable power. | 02-23-2012 |
Gregory Mauro, San Diego, CA US
Patent application number | Description | Published |
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20150035665 | Vehicle Exception Event Management Systems - Exception event recorders and analysis systems include: vehicle mounted sensors arranged as a vehicle event recorder to capture both discrete and non-discrete data; a discretization facility; a database; and an analysis server all coupled together as a computer network. Motor vehicles with video cameras and onboard diagnostic systems capture data when the vehicle is involved in a crash or other anomaly (an ‘event’). In station where interpretation of non-discrete data is rendered, i.e. a discretization facility, captured data is used as a basis for production of supplemental discrete data to further characterize the event. Such interpreted data is joined to captured data and inserted into a database in a structure which is searchable and which supports logical or mathematical analysis by automated machines. A coupled analysis server is arranged to test stored data for prescribed conditions and upon finding such, to initiate further actions appropriate for the detected condition. | 02-05-2015 |
20150057836 | VEHICLE OPERATOR PERFORMANCE HISTORY RECORDING, SCORING AND REPORTING SYSTEMS - A driver history report may include many factors to express performance or quality of driver service. Vehicle event recorders are coupled to systems which form an association between collected data and the vehicle operator in command of the vehicle at the event moment. Systems provide means for long-term storage of data particularly data in a structure which preserves the association between a driver and event records attributed to him. Special recall operations executed against stored data yields operator performance reporting—including a single value performance score indicative of a vehicle operator's performance and safety history. An analyzer system operates to recall data, particularly data from a plurality of events all associated with a single operator but recorded over an extended period of time. Data is arranged such that mathematical analysis may be applied independently to various data elements or data “fields” to produce performance metrics and ratios which reflect performance. | 02-26-2015 |
James R. Mauro, Greer, SC US
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20100276509 | Drinking straw with filter member - A drinking straw that has a filter member is provided. In one embodiment, an outer wall extends in a longitudinal direction and has an outer surface that is curved. A central axis is located at the radial center of the outer wall and extends in the longitudinal direction. The outer wall has a first end and an oppositely disposed second end in the longitudinal direction. The first and second ends are open to allow the flow of fluid longitudinally through the outer wall. A filter member is present and at least partially defines a channel. The central axis may extend through the channel. | 11-04-2010 |
Jeffry Mauro, Montgomery, NY US
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20140161374 | CHILD-RESISTANT RECLOSABLE BAGS - The present disclosure relates to plastic or polymeric container with reclosable zippers which make the package child-resistant. In one typical embodiment, this is achieved by a zipper with a high internal opening force and a low external opening force, wherein three flanges are sealed to the bag walls, and one external flange is left unsealed. In order to encounter the low external opening force, the user must grab the unsealed external flange while applying an external opening force to the zipper. | 06-12-2014 |
Jeffry C. Mauro, Montgomery, NY US
Patent application number | Description | Published |
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20110185543 | SEAL APERTURES THROUGH PACKAGE RECLOSURE - A reclosable zipper is provided having first and second opposing profiles forming at least one pair of opposing flanges. The flanges have cutouts, such as notches or apertures, disposed adjacent to side edges of the profiles so as to define at least one pair of cutouts. When the profiles are sealed to opposing inner surfaces of package panels, portions of the panels seal to each other through the at least one pair of cutouts, providing a reinforcing structure to opposing ends of the zippers, thereby preventing the zipper ends from separating upon opening the package. | 08-04-2011 |
J. Matthew Mauro, Eugene, OR US
Patent application number | Description | Published |
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20090048123 | Reagentless and Reusable Biosensors with Tunable Differential Binding Affinities and Methods of Making - The biosensor comprises a modular biorecognition element and a modular flexible arm element. The biorecognition element and the flexible arm element are each labeled with a signaling element. The flexible arm contains an analog of an analyte of interest that binds with the biorecognition element, bringing the two signaling elements in close proximity, which establishes a baseline fluorescence resonance energy transfer (FRET). When an analyte of interest is provided to the biosensor, the analyte will displace the analyte analog, and with it, the signaling module of the modular flexible arm, causing a measurable change in the FRET signal in a analyte concentration dependent manner. The modularity of different portions of the biosensor allows functional flexibility. The biosensor operates without additional development reagents, requiring only the presence of analyte or target for function. | 02-19-2009 |
J. Matthew Mauro, Silver Spring, MD US
Patent application number | Description | Published |
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20090325261 | Passivation of nerve agents by surface modified enzymes stabilized by non-covalent immobilization on robust, stable particles - Enzymes are modified by incorporating anchor sites for linking the enzymes to a target surface without destroying the catalytic activity of the enzymes. A stable carrier to accommodate and bind the selected enzyme is constructed, and the enzyme is non-covalently liked to the carrier, generally through metal salts of iminodiacetate | 12-31-2009 |
20100308275 | Inorganic particle conjugates - The ionic conjugates include an inorganic particle electrostatically associated with a macromolecule which can interact specifically with predetermined chemical species or biological targets. | 12-09-2010 |
20110319601 | Inorganic Particle Conjugates - The ionic conjugates include an inorganic particle electrostatically associated with a macromolecule which can interact specifically with predetermined chemical species or biological targets. | 12-29-2011 |
John Mauro, Eugene, OR US
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20090155182 | OPTICAL IN VIVO IMAGING CONTRAST AGENTS AND METHODS OF USE - Provided is an optical in vivo contrast agent comprising a fluorescent polymeric microsphere, wherein the microsphere is impregnated with a dye having an excitation and emission spectrum compatible with in vivo imaging, and wherein the microsphere is coated with a block copolymer. | 06-18-2009 |
20090311193 | METHODS AND REAGENTS FOR IN VIVO IMAGING OF CANCER CELL LINES - Provided are reagents and methods for non-invasive in vivo imaging wherein the reagents comprise targeted carrier molecules conjugated to a NIR reporter molecule. In one aspect the targeted carrier molecule is an antibody, or fragment thereof that has specificity for an antigen in a living body, animal or human. In one embodiment the antibodies are anti-cancer/tumor marker antibodies, organ specific antibodies, tissue specific antibodies, cell type specific antibodies, cell surface specific antibodies, anti-viral antibodies, anti-bacterial antibodies and anti-pathogenic antibodies. The NIR reporter molecules are any fluorescent reporter molecule compatible with in vivo imaging and generally having an excitation wavelength of at least 580 nm. | 12-17-2009 |
20110220844 | SULFONATE MODIFIED NANOCRYSTALS - A nanoparticle having one or more phosphonates or phosphinate ligands on their surface can be converted into nanoparticles with sulfonate ligands on their surface, by contacting the phosphonate-containing nanoparticles with a silylsulfonate reagent. Such nanoparticles are activated toward reactions with nucleophilic groups; thus the method provides activated nanoparticles, and methods of making and using them to produce modified nanoparticles. | 09-15-2011 |
20110306079 | WATER-DISPERSABLE NANOPARTICLES - Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided. | 12-15-2011 |
20120253160 | Methods and Reagents for in Vivo Imaging of Cancel Cell Lines - Provided is reagents and methods for non-invasive in vivo imaging wherein the reagents comprise targeted carrier molecules conjugated to a NIB reporter molecule. In one aspect the targeted carrier molecule is an antibody, or fragment thereof that has specificity for an antigen in a living body, animal or human. In one embodiment the antibodes are anti-cancer/tumor marker antibodies, organ specific antibodies, tissue specific antibodies, cell type specific antibodies, cell surface specific antibodies, anti-viral antibodies, anti-bacterial antibodies and anti-pathogenic antibodies. The NIP reporter molecules are any fluorescent reporter molecule compatible with in vivo imaging and generally having an excitation wavelength of at least 580 nm. | 10-04-2012 |
20120276015 | Optical in vivo Imaging Contrast Agents and Methods of Use - Provided is an optical in vivo contrast agent comprising a fluorescent polymeric microsphere, wherein the micro-sphere is impregnated with a dye having an excitation and emission spectrum compatible with in vivo imaging, and wherein the microsphere is coated with a block copolymer. | 11-01-2012 |
20150233936 | WATER-DISPERSABLE NANOPARTICLES - Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided. | 08-20-2015 |
John Mauro, Burlingame, CA US
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20120045368 | Chemical Coating of Microwell for Electrochemical Detection Device - The described embodiments may provide a method of fabricating a chemical detection device. The method may comprise forming a microwell above a CMOS device. The microwell may comprise a bottom surface and sidewalls. The method may further comprise applying a first chemical to be selectively attached to the bottom surface of the microwell, forming a metal oxide layer on the sidewalls of the microwell, and applying a second chemical to be selectively attached to the sidewalls of the microwell. The second chemical may lack an affinity to the first chemical. | 02-23-2012 |
20130089466 | Chemical Coating of Microwell for Electrochemical Detection Device - The described embodiments may provide a method of fabricating a chemical detection device. The method may comprise forming a microwell above a CMOS device. The microwell may comprise a bottom surface and sidewalls. The method may further comprise applying a first chemical to be selectively attached to the bottom surface of the microwell, forming a metal oxide layer on the sidewalls of the microwell, and applying a second chemical to be selectively attached to the sidewalls of the microwell. The second chemical may lack an affinity to the first chemical. | 04-11-2013 |
John C. Mauro, Painted Post, NY US
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20090093371 | MEMBRANE ARRAYS AND METHODS OF MANUFACTURE - The invention relates to G protein-coupled receptor (GPCR) microarrays on porous substrates for structural or functional analyses of GPCRs, and methods of preparing porous substrate surfaces for receiving membranes that comprise GPCRs. In one embodiment, a GPCR microarray of the invention comprises a membrane adhered to an upper surface of a porous substrate, the membrane spanning across a plurality of pores on the porous substrate to form a plurality of cavities having sufficient geometry to permit entry of assay reagents into each cavity, thereby allowing access of assay reagents to both sides of GPCR in the membrane. | 04-09-2009 |
John C. Mauro, Corning, NY US
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20130233019 | METHODS FOR REDUCING ZIRCONIA DEFECTS IN GLASS SHEETS - Methods are disclosed for treating zircon-containing forming structures, e.g., zircon isopipes, with one or more treatment glass compositions in which defect-causing reactions between the zircon of the forming structure and molten glass are suppressed at the delivery temperature of the treatment glass. The treatment compositions can be used during start-up of a forming structure, between runs of the same production glass on a given forming structure, and/or when transitioning between runs of two production glasses on a given forming structure. The treatment compositions can be used with production glasses that are ion-exchangeable. | 09-12-2013 |
20130255314 | METHOD FOR FUSION DRAWING ION-EXCHANGEABLE GLASS - A method of making glass through a glass ribbon forming process in which a glass ribbon is drawn from a root point to an exit point is provided. The method comprises the steps of: (I) cooling the glass ribbon at a first cooling rate from an initial temperature to a process start temperature, the initial temperature corresponding to a temperature at the root point; (II) cooling the glass ribbon at a second cooling rate from the process start temperature to a process end temperature; and (III) cooling the glass ribbon at a third cooling rate from the process end temperature to an exit temperature, the exit temperature corresponding to a temperature at the exit point, wherein an average of the second cooling rate is lower than an average of the first cooling rate and an average of the third cooling rate. | 10-03-2013 |
John Christopher Mauro, Corning, NY US
Patent application number | Description | Published |
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20110265516 | COMPOSITIONAL CONTROL OF FAST RELAXATION IN DISPLAY GLASSES - Methods are provided for reducing the dimensional changes of a glass substrate during a display manufacturing process. The reductions are achieved by increasing the fast relaxation exhibited by the glass. Test methods are provided for distinguishing the effects on dimensional changes of fast relaxation versus slow relaxation. Glass substrates which exhibit reduced dimensional changes during critical thermal cycles of display manufacturing processes are also disclosed. | 11-03-2011 |
20120083915 | METHODS AND APPARATUS FOR PREDICTING GLASS PROPERTIES - Methods and apparatus for predicting viscosities of glass materials as a function of temperature and composition are provided. Two fitting parameters (fitting coefficients) are used for each of the viscosity-affecting components contained in the material. The parameters can accurately cover a wide range of temperatures (i.e., a wide range of viscosities) and a wide range of compositions. The viscosity predictions can be used as a guide for glass research as well as in feedback control systems for glass manufacturing processes. Methods and apparatus for predicting glass resistivity are also disclosed. | 04-05-2012 |
20130004758 | ION EXCHANGEABLE GLASS WITH HIGH COMPRESSIVE STRESS - An aluminosilicate glass article having a high compressive stress layer. The glass article comprises at least about 50 mol % SiO | 01-03-2013 |
20130037105 | FUSION FORMABLE ALKALI-FREE INTERMEDIATE THERMAL EXPANSION COEFFICIENT GLASS - A compositional range of high strain point and/or intermediate expansion coefficient alkali metal free aluminosilicate and boroaluminosilicate glasses are described herein. The glasses can be used as substrates or superstrates for photovoltaic devices, for example, thin film photovoltaic devices such as CdTe or CIGS photovoltaic devices or crystalline silicon wafer devices. These glasses can be characterized as having strain points ≧600° C., thermal expansion coefficient of from 35 to 50×10 | 02-14-2013 |
20130136909 | COLORED ALKALI ALUMINOSILICATE GLASS ARTICLES - A glass article including at least about 40 mol % SiO | 05-30-2013 |
20130224491 | ALUMINOSILICATE GLASSES FOR ION EXCHANGE - Glass compositions that may be used to produce chemically strengthened glass sheets by ion exchange. The glass compositions are chosen to promote simultaneously high compressive stress and deep depth of layer or, alternatively, to reduce the time needed to ion exchange the glass to produce a predetermined compressive stress and depth of layer. | 08-29-2013 |
20130225390 | HIGH STRAIN POINT ALUMINOSILICATE GLASSES - Described herein are alkali-free, boroalumino silicate glasses exhibiting desirable physical and chemical properties for use as substrates in flat panel display devices, such as, active matrix liquid crystal displays (AMLCDs) and active matrix organic light emitting diode displays (AMOLEDs). In accordance with certain of its aspects, the glasses possess good dimensional stability as a function of temperature. | 08-29-2013 |
20130233020 | METHODS FOR PRODUCING ION-EXCHANGEABLE GLASSES - Computer-implemented methods and apparatus are provided for predicting/estimating chemical depth of layer (DOL) and maximum surface compressive stress (CS) of glass articles after ion-exchange. The methods and apparatus can, for example, be used to select glass compositions, salt bath temperatures, and/or ion-exchange times which provide desired DOL and/or CS values. One or more manufacturing constraints, e.g., constraints on liquidus viscosity, zircon breakdown viscosity, and the like, can be applied to the process of predicting/estimating DOL and/or CS values so that glass compositions selected based on DOL and/or CS values can, for example, be manufactured commercially by a fusion or float process. | 09-12-2013 |
20130260154 | HEAT TREATMENT FOR STRENGTHENING GLASSES - A method of making a strengthened glass article. The method includes altering the glass structure and subsequently creating a compressive layer extending from the surface of the glass to a depth of layer. In some embodiments, the structure is altered by heat treating the glass at a temperature that is less than the annealing point of the glass, and the compressive layer is formed by ion exchange. A strengthened glass article made by the method is also provided. | 10-03-2013 |
20140050911 | ULTRA-THIN STRENGTHENED GLASSES - Glass compositions having properties that are optimized for forming ultra-thin (<0.4 mm) articles and for applications requiring ultra-thin glass. These properties include both forming-related properties such as the coefficients of thermal expansion (CTE) of both the liquid and glassy state of the glass, liquidus viscosity, and those properties affecting the mechanical performance of the glass (compressive stress, depth of layer, elastic or Young's modulus). | 02-20-2014 |
20140106172 | ION EXCHANGEABLE GLASS WITH HIGH DAMAGE RESISTANCE - An ion exchangeable glass having a high degree of resistance to damage caused by abrasion, scratching, indentation, and the like. The glass comprises alumina, B | 04-17-2014 |
20140186632 | ZIRCON COMPATIBLE, ION EXCHANGEABLE GLASS WITH HIGH DAMAGE RESISTANCE - An ion exchangeable glass having a high degree of resistance to damage caused by abrasion, scratching, indentation, and the like. The glass comprises alumina, B | 07-03-2014 |
20140230490 | METHODS FOR REDUCING ZIRCONIA DEFECTS IN GLASS SHEETS - Methods are disclosed for treating zircon-containing forming structures, e.g., zircon isopipes, with one or more treatment glass compositions in which defect-causing reactions between the zircon of the forming structure and molten glass are suppressed at the delivery temperature of the treatment glass. The treatment compositions can be used during start-up of a forming structure, between runs of the same production glass on a given forming structure, and/or when transitioning between runs of two production glasses on a given forming structure. The treatment compositions can be used with production glasses that are ion-exchangeable. | 08-21-2014 |
20140242375 | LAMINATED GLASS ARTICLES WITH PHASE-SEPARATED CLADDINGS AND METHODS FOR FORMING THE SAME - Laminated glass articles and methods for making the same are disclosed. In one embodiment, a laminated glass article may include a glass core layer and at least one glass cladding layer fused to the glass core layer. The at least one glass cladding layer may be phase separated into a first phase and at least one second phase having different compositions. The first phase of the at least one glass cladding layer may have an interconnected matrix. The at least one second phase of the at least one glass cladding layer may be dispersed throughout the interconnected matrix of the first phase of the at least one glass cladding layer. In some embodiments, the at least one second phase may be selectively removed from the interconnected matrix leaving a porous, interconnected matrix of the first phase. | 08-28-2014 |
20140335331 | ALKALI-FREE PHOSPHOBOROSILICATE GLASS - Alkali-free phosphoboroaluminosilicate glasses are provided. The glasses include the network formers SiO | 11-13-2014 |
20140356576 | DOWN-DRAWABLE CHEMICALLY STRENGTHENED GLASS FOR INFORMATION STORAGE DEVICES - Described herein are various glass compositions, glass articles, and information storage devices that comprise the glass articles as substrates therefor, along with methods for their manufacture and use. | 12-04-2014 |
20150030827 | LOW CTE, ION-EXCHANGEABLE GLASS COMPOSITIONS AND GLASS ARTICLES COMPRISING THE SAME - Glass compositions and glass articles comprising the glass compositions are disclosed. In one embodiment, a glass composition includes from about 65 mol. % to about 70 mol. % SiO2; from about 9 mol. % to about 14 mol. % Al | 01-29-2015 |
20150037552 | HIGH CTE POTASSIUM BOROSILICATE CORE GLASSES AND GLASS ARTICLES COMPRISING THE SAME - High CTE glass compositions and laminated glass articles formed from the same are described. In one embodiment, a glass composition may include from about 70 mol. % to about 80 mol. % SiO | 02-05-2015 |
20150037553 | LOW CTE ALKALI-FREE BOROALUMINOSILICATE GLASS COMPOSITIONS AND GLASS ARTICLES COMPRISING THE SAME - Low CTE glass compositions and glass articles formed from the same are described. In one embodiment, a glass composition includes from about 60 mol. % to about 66 mol. % SiO | 02-05-2015 |
20150051060 | ALKALI-DOPED AND ALKALI-FREE BOROALUMINOSILICATE GLASS - Alkali-doped boroaluminosilicate glasses are provided. The glasses include the network formers SiO | 02-19-2015 |
20150051061 | INTERMEDIATE TO HIGH CTE GLASSES AND GLASS ARTICLES COMPRISING THE SAME - Intermediate to high CTE glass compositions and laminates formed from the same are described. The glasses described herein have properties, such as liquidus viscosity or liquidus temperature, which make them particularly well suited for use in fusion forming processes, such as the fusion down draw process and/or the fusion lamination process. Further, the glass composition may be used in a laminated glass article, such as a laminated glass article formed by a fusion laminate process, to provide strengthened laminates via clad compression as a result of CTE mismatch between the core glass and clad glass. | 02-19-2015 |
20150064474 | Ion Exchangeable Glass, Glass Ceramics and Methods for Making the Same - Glass-ceramics and precursor glasses that are crystallizable to glass-ceramics are disclosed. The glass-ceramics of one or more embodiments include rutile, anatase, armalcolite or a combination thereof as the predominant crystalline phase. Such glasses and glass-ceramics may include compositions of, in mole %: SiO | 03-05-2015 |
20150099130 | REVERSE PHOTOCHROMIC BOROSILICATE GLASSES - Borosilicate glasses are disclosed having (in weight %) 66-76% SiO | 04-09-2015 |
20150118497 | ZIRCON COMPATIBLE, ION EXCHANGEABLE GLASS WITH HIGH DAMAGE RESISTANCE - An ion exchangeable glass having a high degree of resistance to damage caused by abrasion, scratching, indentation, and the like. The glass comprises alumina, B | 04-30-2015 |
20150132579 | ION EXCHANGEABLE TRANSITION METAL-CONTAINING GLASSES - Ion exchangeable glasses that comprise at least one of a transition metal oxide or a rare earth oxide and have compositions that simultaneously promote a surface layer having a high compressive stress and deep depth of layer or, alternatively, reduced ion exchange time. | 05-14-2015 |
20150140299 | SCRATCH-RESISTANT BOROALUMINOSILICATE GLASS - Ion exchangeable boroaluminosilicate glasses having high levels of intrinsic scratch resistance are provided. The glasses include the network formers SiO | 05-21-2015 |
20150147575 | FAST ION EXCHANGEABLE GLASSES WITH HIGH INDENTATION THRESHOLD - Alkali aluminosilicate glasses that are ion exchangeable to high compressive stresses, have fast ion exchange kinetics, and high intrinsic damage resistance. The glasses achieve all of the above desired properties either with only small amounts of P | 05-28-2015 |
20150158758 | Fusion Formable Alkali-Free Intermediate Thermal Expansion Coefficient Glass - A compositional range of high strain point and/or intermediate expansion coefficient alkali metal free aluminosilicate and boroaluminosilicate glasses are described herein. The glasses can be used as substrates or superstrates for photovoltaic devices, for example, thin film photovoltaic devices such as CdTe or CIGS photovoltaic devices or crystalline silicon wafer devices. These glasses can be characterized as having strain points ≧600° C., thermal expansion coefficient of from 35 to 50×10 | 06-11-2015 |
20150239777 | HIGH STRENGTH ANTIMICROBIAL GLASS - A method of making a glass having antimicrobial properties and high compressive stress. The method includes a first ion exchange step in which potassium cations are exchanged for sodium cations in the base glass to provide a surface layer under compressive stress, followed by a second ion exchange in which silver cations are exchanged for potassium and lithium ions in the glass to produce the antimicrobial glass. In some embodiments, the antimicrobial glass has a maximum compressive stress that is at least 80% of the maximum compressive stress obtained by the potassium-for-sodium exchange in the first bath. A base glass and an ion exchanged glass antimicrobial having antimicrobial properties are also provided. | 08-27-2015 |
20150368147 | FICTIVATED GLASS AND METHOD OF MAKING - Silicate glasses that are fictivated and fast cooled and have high levels of intrinsic or “native” damage resistance. When ion exchanged, the silicate glasses described herein have a Vickers crack initiation threshold of at least 15 kgf and, in some embodiments, at least about 25 kgf. | 12-24-2015 |
20150368149 | TRANSITION METAL-CONTAINING, ION EXCHANGEABLE COLORED GLASSES - Glasses that can be chemically strengthened and are colored by transition metals. Most of the glasses are black, with some having high damage resistance and compressive surface layers having high compressive stress and depth of layer after ion exchange. These colored glasses do not require a post-forming heat treatment to produce color and are formable by fusions drawing, rolling, slot drawing, and float glass processes. | 12-24-2015 |
20160039708 | HIGH STRAIN POINT ALUMINOSILICATE GLASSES - Described herein are alkali-free, boroalumino silicate glasses exhibiting desirable physical and chemical properties for use as substrates in flat panel display devices, such as, active matrix liquid crystal displays (AMLCDs) and active matrix organic light emitting diode displays (AMOLEDs). In accordance with certain of its aspects, the glasses possess good dimensional stability as a function of temperature. | 02-11-2016 |
20160060161 | METHODS AND APPARATUS FOR STRENGTH AND/OR STRAIN LOSS MITIGATION IN COATED GLASS - Methods and apparatus provide for: a glass substrate having a first strain to failure characteristic, a first elastic modulus characteristic, and a flexural strength; and a coating applied over the glass substrate to produce a composite structure in order to increase a hardness thereof, where the coating has a second strain to failure characteristic and a second elastic modulus characteristic, where the first strain to failure characteristic is higher than the second strain to failure characteristic, and one of: (i) the first elastic modulus characteristic is above a minimum predetermined threshold such that any reduction of the flexural strength of the glass substrate resulting from application of the coating is mitigated; and (ii) the first elastic modulus characteristic is below a maximum predetermined threshold such that any reduction of the strain to failure of the glass substrate resulting from application of the coating is mitigated. | 03-03-2016 |
John M. Mauro, Burlingame, CA US
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20140113303 | Chemical Coating of Microwell for Electrochemical Detection Device - The described embodiments may provide a method of fabricating a chemical detection device. The method may comprise forming a microwell above a CMOS device. The microwell may comprise a bottom surface and sidewalls. The method may further comprise applying a first chemical to be selectively attached to the bottom surface of the microwell, forming a metal oxide layer on the sidewalls of the microwell, and applying a second chemical to be selectively attached to the sidewalls of the microwell. The second chemical may lack an affinity to the first chemical. | 04-24-2014 |
John M. Mauro, Eugene, OR US
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20110003343 | CONJUGATES OF BIOMOLECULES TO NANOPARTICLES - Disclosed herein are conjugates comprising a biomolecule linked to a label that have biological activity and are useful in a wide variety of biological applications. For example, provided herein are polymerase-nanoparticle conjugates including a polymerase linked to a nanoparticle, wherein the conjugate has polymerase activity. Such conjugates can exhibit reduced aggregation and improved stochiometries wherein the average biomolecule:nanoparticle ratio approaches or equals 1:1. Also disclosed herein are improved methods for preparing such conjugates, and methods and systems for using such conjugates in biological applications such as nucleotide incorporation, primer extension and single molecule sequencing. | 01-06-2011 |
John Matthew Mauro, Eugene, OR US
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20100009342 | CONTROL OF CHEMICAL MODIFICATION - Provided is a method for controlling the degree of labeling (DOL) of a carrier molecule or solid support by the addition of a reactive label competitor to the labeling reaction. When the reactive label competitor is added to the labeling solution the competitor competes with the carrier molecule or solid support for the label, reducing the number of labels available to conjugates to the carrier molecule or solid support. This provides for a facile method that predictably alters the DOL of a carrier molecule or solid support. | 01-14-2010 |
Joseph Kendall Mauro, Cincinnati, OH US
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20110110792 | SENSORS AND METHODS AND APPARATUS RELATING TO SAME - In one form a capacitive sensor is disclosed for immersion into a fluid, the capacitive sensor having a housing and first and second electrodes with the first electrode being disposed at least partially within the housing and electrically connected to a circuit, the second electrode being electrically connected to the circuit via an electrical connection and physically separated from the housing containing at least a portion of the first electrode so that at least a portion of the electrical connection or second electrode is located above or outside of the fluid to reduce the risk that minerals will form between the electrodes. In other forms, capacitors, capacitive sensors, pump controls and systems utilizing these features are disclosed along with methods and apparatus relating to same. In yet other forms additional sensors such as current sensors, thermal sensors, speed sensors, torque sensors and Hall Effect sensors are disclosed for use alone or in combination with said capacitive sensor for detecting fluid level and/or controlling pumps. | 05-12-2011 |
Joseph L. Mauro, Jersey Shore, PA US
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20120036006 | ADVERTISING MEDIA TRACKING - A system tracks the effectiveness of advertising across both on-line and off-line media. Users define advertisements that are part of an advertising campaign and include in the definition tracking identifiers such as telephone numbers and URL's. The system tracks inputs that are subsequently received in response to and generated by the various advertisements. The inputs contain tracking identifier information. The system correlates the tracking identifier information from the received user inputs with tracking identifier information entered upon definition of advertisements in the system. Thereafter, the system generates reports that illustrate the relative effectiveness of the advertisements in driving inputs. | 02-09-2012 |
20130085803 | BRAND ANALYSIS - A system provides an analysis of a the strength or weakness of a brand as reflected in both on-line and off-line media. The system automatically retrieves data relating to a particular brand from a plurality of different media channels which may reflect inputs received from the various media channels, perhaps in response to advertisement campaigns. The system generates a score for each media channel which reflects a comparison of the inputs that were received for the brand relative to other similarly situated entities. An aggregate score is generated from the scores that have been generated for the various media channels. Scores and analysis reflecting a relative strength and weakness for a brand are presented. | 04-04-2013 |
Karen Ellen Mauro, Valhalla, NY US
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20160083147 | PROTECTIVE BAG - A protective bag is provided. The protective bag may be made out of a temperature insulating and a waterproof material. The protective bag may include a front wall, a rear wall, a first sidewall, a second sidewall, a top portion and a bottom portion. An opening is formed at the top portion leading into an internal compartment. A waterproof sealer may be attached to the material at the opening and may releasably open and close the opening. The protective bag may be used while at the beach to secure and protect valuables. | 03-24-2016 |
Marcus J. Mauro, Felton, CA US
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20140115304 | COMPRESSED INSTRUCTION CODE STORAGE - Computer implemented techniques are disclosed for identification of repeated binary strings and for storing those binary strings in order to compress code. The binary strings can be longer instructions, data, or addresses. A table of binary strings is generated based on repeated occurrences, and a reference index is provided for accessing specific entries within the table. An opcode uses a shorter string as an index through which to access the table. The longer string is executed when the longer string is an instruction. When the longer string is an address or data, the appropriate address or data are accessed. | 04-24-2014 |
Meliga Mauro US
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20150224554 | BENDING MACHINES FOR BENDING PROFILES, METAL SHEETS AND THE LIKE - Machines for bending profiles, metal sheets and the like are provided. Such machines include those having a structure or frame and a bending device with three rollers. The axis (x | 08-13-2015 |
Patrick Mauro, Lake Grove, NY US
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20100127078 | Integrated image quality test for imaging system - An imaging system with in-field image quality testing and reporting features, includes a housing, and a solid-state imager having an array of image sensors supported by the housing for capturing return light from a target located in a range of working distances from the housing in an image capture mode of operation, and for capturing return light from a test pattern positioned at a predetermined position in the range of working distances in a test mode of operation different from the image capture mode. An electrical signal indicative of the captured return light is generated in each mode. A memory is supported by the housing for storing a test program for testing image quality. A controller is supported by the housing for processing the electrical signal in the image capture mode, and for accessing the memory to enable the controller to execute the test program in the test mode to test the image quality of the test pattern imaged by the imaging system, and for reporting test results of the image quality of the test pattern. | 05-27-2010 |
20100213256 | Imaging reader for and method of processing a plurality of data on a target per single actuation - An imaging reader for, and a method of, processing a plurality of data, such as one or more symbols having the same or different symbologies, a receipt acknowledgment, and an alphanumeric address arranged at spaced-apart locations on a target, such as at parcel delivery label, employ a solid-state imager having an array of image sensors for capturing return light from the data on the target over a field of view, an actuator for actuating the images: to capture the return light from the data on the target in a single actuation, and a controller automatically configured for detecting all the data and the spaced-apart locations at which the data is arranged over the field of view, and for processing the return light captured by the imager from all the data only when all the data is of a predetermined type and is at predetermined locations on the target, in response to the single actuation. | 08-26-2010 |
Peter Matthew Mauro, Los Angeles, CA US
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20140244616 | APPARATUS AND METHOD FOR PROVIDING CONTACT-RELATED INFORMATION ITEMS - Mechanisms are provided for determining contact-related information items for presentation to a user, such that the user can refer to the information items to enhance the user's communication with the contact. Contact-related information items that have a high relevance level may be accessed and presented to the user. In a case in which no or limited high relevance level information items exist, contact-related information items associated with incrementally lower levels of relevance may be accessed and presented. Moreover, according to some example embodiments, relevance may be derived based on the relationship of the user with the particular contact and/or the frequency of communications with the contact. | 08-28-2014 |
20140244630 | APPARATUS AND METHOD FOR PROVIDING CONTACT-RELATED INFORMATION ITEMS - Mechanisms are provided for determining contact-related information items for presentation to a user, such that the user can refer to the information items to enhance the user's communication with the contact. Contact-related information items that have a high relevance level may be accessed and presented to the user. In a case in which no or limited high relevance level information items exist, contact-related information items associated with incrementally lower levels of relevance may be accessed and presented. Moreover, according to some example embodiments, relevance may be derived based on the relationship of the user with the particular contact and/or the frequency of communications with the contact. | 08-28-2014 |
20140245180 | APPARATUS AND METHOD FOR PROVIDING CONTACT-RELATED INFORMATION ITEMS - Mechanisms are provided for determining contact-related information items for presentation to a user, such that the user can refer to the information items to enhance the user's communication with the contact. Contact-related information items that have a high relevance level may be accessed and presented to the user. In a case in which no or limited high relevance level information items exist, contact-related information items associated with incrementally lower levels of relevance may be accessed and presented. Moreover, according to some example embodiments, relevance may be derived based on the relationship of the user with the particular contact and/or the frequency of communications with the contact. | 08-28-2014 |
Robert Mauro, Miller Place, NY US
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20140100260 | Enalapril Compositions - Provided herein are stable enalapril powder compositions for oral liquid formulation. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction. | 04-10-2014 |
20150258027 | ENALAPRIL COMPOSITIONS - Provided herein are stable enalapril powder compositions for oral liquid formulation. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction. | 09-17-2015 |
Vincent P. Mauro, San Diego, CA US
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20090093049 | Methods of Identifying Synthetic Transcriptional and Translational Regulatory Elements, and Compositions Related to Same - Provided are methods of identifying oligonucleotides having transcriptional or translational activity by integrating ilie oligonucleotide into a eukaryotic cell genome such that the oligonucleotide is operatively linked to an expressible polynucleotide, and detecting a change in expression of the expressible polynucleotide due to the operatively linked oligonucleotide. Also provided are vectors useful for identifying an oligonucleotide having transcriptional or translational regulatory activity according to a method of the invention. In addition, isolated synthetic transcriptional or translational regulatory elements identified according to a method of the invention are provided, as are kits, which contain a vector useful for identifying a transcriptional or translational regulatory element, or an isolated synthetic transcriptional or translational regulatory element or plurality of such elements. Also provided are isolated transcriptional regulatory elements. | 04-09-2009 |
20110124100 | TRANSLATION ENHANCER-ELEMENT DEPENDENT VECTOR SYSTEMS - A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element (TEE) and to provide a means for overexpression of gene products. The system exploits both transcriptional and translational approaches to control the expression levels of genes and/or gene products. Methods are also disclosed for screening libraries of random nucleotide sequences to identify translational elements and for overproduction of proteins, which have uses in both research and industrial environments. | 05-26-2011 |
20120258541 | CHROMOSOMAL LANDING PADS AND RELATED USES - Provided herein are methods for stable integration and/or expression of one or more recombinant polynucleotides in a host cell. The recombinant polynucleotides are typically integrated into the host genome at some native chromosomal integration sites. The integration can be mediated by homologous recombination or by using a hybrid recombinase targeting the specific chromosomal locations. The native chromosomal integration sites in the host cells, which support stable integration and strong transcription activities of foreign genes, are present within or adjacent to specific genes in the CHO genome, ankyrin 2 gene (Ank2), cleavage and polyadenylation specific factor 4 gene (Cpsf4), C-Mos gene, and Nephrocystin-1/Mal gene. Also provided are methods and nucleic acid molecules for inserting site-specific recombination sequences (chromosomal landing pads) into these specific chromosomal locations, engineered host cells containing chromosomal landing pads, methods and compositions (e.g., kits) therefore. | 10-11-2012 |
20130177581 | Compositions and Methods Related to mRNA Translational Enhancer Elements - Provided are mRNA translational enhancer elements (TEEs), e.g., SEQ ID NOs:1-35. Also provided are translational enhancer polynucleotides that comprise one or more of the specific TEEs exemplified herein or their variants, homologs or functional derivatives. Further provided are expression vectors comprising such TEEs or translational enhancer polynucleotides, as well as host cells and expression systems that harbor such vectors. | 07-11-2013 |
20140370545 | Reengineering mRNA Primary Structure for Enhanced Protein Production - Described herein are rules to modify natural mRNAs or to engineer synthetic mRNAs to increase their translation efficiencies. These rules describe modifications to mRNA coding and 3′ UTR sequences intended to enhance protein synthesis by: 1) decreasing ribosomal diversion via AUG or non-canonical initiation codons in coding sequences, and/or 2) by evading miRNA-mediated down-regulation by eliminating one or more miRNA binding sites in coding sequences. | 12-18-2014 |
20150152437 | Chromosomal Landing Pads and Related Uses - Provided herein are methods for stable integration and/or expression of one or more recombinant polynucleotides in a host cell. The recombinant polynucleotides are typically integrated into the host genome at some native chromosomal integration sites. The integration can be mediated by homologous recombination or by using a hybrid recombinase targeting the specific chromosomal locations. The native chromosomal integration sites in the host cells, which support stable integration and strong transcription activities of foreign genes, are present within or adjacent to specific genes in the CHO genome, ankyrin 2 gene (Ank2), cleavage and polyadenylation specific factor 4 gene (Cpsf4), C-Mos gene, and Nephrocystin-1/Mal gene. Also provided are methods and nucleic acid molecules for inserting site-specific recombination sequences (chromosomal landing pads) into these specific chromosomal locations. Further provided are engineered host cells which contain chromosomal landing pads or transgenes integrated into the native chromosomal integration sites. Further provided are methods and compositions (e.g., kits) for integrating and expressing heterologous polynucleotides in host cells bearing inserted chromosomal landing pads. | 06-04-2015 |
20150267190 | TRANSLATIONAL ENHANCER-ELEMENT DEPENDENT VECTOR SYSTEMS - A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element (TEE) and to provide a means for overexpression of gene products. The system exploits both transcriptional and translational approaches to control the expression levels of genes and/or gene products. Methods are also disclosed for screening libraries of random nucleotide sequences to identify translational elements and for overproduction of proteins, which have uses in both research and industrial environments. | 09-24-2015 |
Vincent P. Mauro, La Jolla, CA US
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20130309682 | Ribosomal Polynucleotides and Related Expression Systems - Provided herein is a synthetic or isolated polynucleotide encoding a mammalian 18S rRNA that is resistant to pactamycin. The pactamycin-resistance is conferred by one or more single residue substitutions in the 18S rRNA sequence; a fragment thereof harboring said substitutions; a complementary sequence thereto; or a substantially identical sequence of the foregoing. Related systems, methods and kits are also described. | 11-21-2013 |
Yihong Mauro, Corning, NY US
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20160082618 | METHOD AND SYSTEM FOR CONTROL OF AN AXIAL SKINNING APPARATUS - A control system for an axial skinning apparatus ( | 03-24-2016 |