Patent application number | Description | Published |
20080215152 | System and Method for Restoration of Nutrient Flow to Nucleus Pulposa - Disclosed are methods and devices for restoring or establishing nutrient flow to the nucleus pulposa. An implant comprises a nutrient flow path for extending between a source of nutrients and the nucleus pulposa. The implant is positioned within the patient such that a first end is in nutrient flow communication with a subject nucleus pulposa, and the source end is positioned in nutrient flow communication with a source of nutrients. | 09-04-2008 |
20100057204 | Hydraulically Actuated Expanding Spine Cage With Extendable Locking Anchor - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning | 03-04-2010 |
20100145455 | Lockable spinal implant - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration. | 06-10-2010 |
20100145456 | Lockable spinal implant - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration. | 06-10-2010 |
20100298768 | Pen Injection Device and Method of Using Same - Pen injection devices ( | 11-25-2010 |
20110130835 | Adjustable Distraction Cage With Linked Locking Mechanisms - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a refracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning | 06-02-2011 |
20110224663 | CONTROL CIRCUITRY FOR A TISSUE ABLATION SYSTEM - A system for providing power suitable for electrosurgery from a self-contained direct current (DC) energy source according to embodiments of the present invention includes a voltage-affecting circuit having an input and an output, wherein the voltage-affecting circuit is configured to receive energy from the DC energy source at the input and provide boosted DC energy at the output, the boosted DC energy having a voltage greater than a voltage of the DC energy source, and an inverter operable to invert the boosted DC energy to alternating current (AC) energy. The inverter may include a bridge circuit including an arrangement of switches and having an input and an output, wherein the boosted DC energy is received at the bridge circuit input, and a bridge controller operable to control the arrangement of switches to selectively connect the bridge circuit input to the bridge circuit output. | 09-15-2011 |
20120130387 | Insertion Handle For Surgical Implants - An insertion handle for medical implants includes a handle with an elongate shaft extending therefrom and connection means for the implant disposed at the end of the shaft opposite the handle. The connection means includes a pivotable attachment for the implant that is controlled remotely from the handle. Both angle of the implant with respect to the handle and shaft as well as the attachment may be separately controlled and adjusted. Remote angular adjustment facilitates insertion of implants in to small surgical sites because the orientation of the implant may be repeatedly, remotely adjusted as the implant is inserted. Connectors may also be provided at the engagement surface between the handle and implant in order to provide communication with the implant or surgical site. The connectors also may serve as torque bearing members to avoid the need for separate torque bearing means such as keyways and the like. | 05-24-2012 |
20120165642 | INTRA-OPERATIVE BLOOD RECOVERY SYSTEM - A method for recovering blood from a blood-laden surgical sponge for autologous reinfusion, the method comprising the steps of: conveying negative pressure to a housing with the blood-laden surgical sponge; applying a predetermined force to draw the blood from the surgical sponge; and collecting the recovered blood. | 06-28-2012 |
20120215200 | PRECISION FLUID DELIVERY SYSTEMS - A precision syringe ( | 08-23-2012 |
20120245695 | Lockable Spinal Implant - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration. | 09-27-2012 |
20120271244 | MEDICAL MALE LUER CONNECTOR WITH INCREASED CLOSING VOLUME - Disclosed herein is a valve assembly comprising a male luer end portion and a female luer end portion and a passage for the transfer of fluids extending between the male and female luer end portions, valve means movable between a first position, in which the passage is closed, and a second position, in which the passage is open, biasing means for biasing the valve means toward the first position, and actuating means extending into the male luer end portion and coupled to the valve means to actuate the valve means when a female luer end portion of a medical accessory is engaged with the male luer end portion. | 10-25-2012 |
20130253631 | SLIDE-AND-LOCK STENT - The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter. | 09-26-2013 |
20130253650 | Adjustable Distraction Cage With Linked Locking Mechanisms - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning. | 09-26-2013 |
20150289988 | ADJUSTABLE DISTRACTION CAGE WITH LINKED LOCKING MECHANISMS - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning. | 10-15-2015 |
Patent application number | Description | Published |
20130261748 | Hydraulically Actuated Expanding Spine Cage with Extendable Locking Anchor - A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning | 10-03-2013 |
20150105782 | ACTUATED POSITIONING DEVICE FOR ARTHROPLASTY AND METHODS OF USE - A joint balancing insert with sensors and an actuated mechanism is disclosed. The joint balancing insert is used to balance a joint during arthroplasty surgery, as the sensors provide force, position and angular data relating to the movement of the joint, while the actuated mechanism allows for highly accurate and dynamic adjustments of the joint based on the data from the sensors. Various configurations of actuated mechanisms and sensors may be implemented in the insert to provide for manual or real time control of the insert, and customized interfaces are provided for visualized feedback of adjustments. Sensor data may also be collected and compared with expected or preferred data sets to provide adjustment recommendations and achieve better outcomes based on historical data. | 04-16-2015 |
20150202054 | INSERTION HANDLE FOR SURGICAL IMPLANTS - An insertion handle for medical implants includes a handle with an elongate shaft extending therefrom and connection means for the implant disposed at the end of the shaft opposite the handle. The connection means includes a pivotable attachment for the implant that is controlled remotely from the handle. Both angle of the implant with respect to the handle and shaft as well as the attachment may be separately controlled and adjusted. Remote angular adjustment facilitates insertion of implants in to small surgical sites because the orientation of the implant may be repeatedly, remotely adjusted as the implant is inserted. Connectors may also be provided at the engagement surface between the handle and implant in order to provide communication with the implant or surgical site. The connectors also may serve as torque bearing members to avoid the need for separate torque bearing means such as keyways and the like. | 07-23-2015 |
Patent application number | Description | Published |
20100222668 | GUIDANCE AND IMPLANTATION OF CATHETERS - A catheter system adapted for navigating, guiding and implanting a catheter or a plurality of catheters in a spatially-defined implantation within the tissue of a patient is provided. The system can include a tissue navigation system and a probe to inform the navigation system to guide emplacement of the catheters within a target tissue. The probe can provide images, such as fiberoptic visual images, or ultrasound images, or can provide radiolocation data, to guide the catheter emplacement. The catheters supply a pressurized liquid including a bioactive agent, such as can be used in the treatment of cancer, for example 123I- or 125I-IUDR. The system and methods provided can be used in the treatment of locally advanced tumors, such as cancers of the brain, head or neck, esophagus, prostate, ovary, liver, pancreas, bladder or rectum. | 09-02-2010 |
20100233081 | METHODS FOR ADMINISTRATION OF RADIOTHERAPEUTIC AGENTS - A method is provided for treatment of disorders involving hyperproliferative cells, such as malignancies, advanced stage solid tumors like glioblastoma multiforme, and non-malignant hyperproliferative pathological conditions such as adult macular degeneration. A short range, unselective cell killing radiotherapeutic substance is administered, optionally in a spatially defined volume of tissue, optionally in combination with a mitogenic agent that stimulates or induces DNA biosynthesis. In this way, the percentage of hyperproliferative that are susceptible to killing by the radiotherapeutic agent is increased. Cancer stem cells can be induced to enter S phase with the mitogenic agent, then killed with the radiotherapeutic agent. Thus, not only does the combination effectively kill the transit amplifying cell population, the most rapidly replicating type of cell in a tumor, but it also effectively kills the tumor stem cells, which give rise to the transit amplifying cells, for a longer lasting anticancer effect. | 09-16-2010 |
20100280494 | CATHETER AND ARRAY FOR ANTICANCER THERAPY - A catheter array system adapted for implanting a plurality of catheters within the tissue of a patient in a spatially defined array, comprising a plurality of catheters, a catheter guide template adapted to guide the implantation of catheters, and a liquid supply system including a pressurizer and a manifold, is provided. A method of treatment of a malcondition in a patient comprises implantation of a spatially definted array of catheters using the system is also provided. The bioactive agent can be a radiotherapeutic agent, a chemotherapeutic agent, a protein, an antibody, an oligonucleotide-based therapeutic agent such as siRNA, or a combination of agents. A preferred radiotherapeutic agent is | 11-04-2010 |
20110135569 | METHOD FOR THERAPEUTIC ADMINISTRATION OF RADIONUCLEOSIDES - Methods are provided for the local radiotherapy of cancers such as locally invasive, advanced stage solid tumors, and normal tissues penetrated by processes of cancerous tissue, through administration of Auger-electron emitting radionucleoside analogs using high-flow microinfusion techniques (“convection-enhanced delivery”). Direct infusion under pressure, at flow rates in excess of at least about 0.5 microliters/min of the radionucleosides provides for their mass transport through tissue to a much higher degree than could be achieved by passive, unpressurized diffusion. The unique properties of these radionucleoside analogs that provide for surprisingly effacacious delivery by high-flow microinfusion include rapid clearance from tissues following local injection without the benefit of sustained high-flow microinfusion, rapid and complete clearance via the blood stream, poor permeation of barriers such as the blood-brain barrier, and a highly potent, non-selective, but very short range killing effect on cells that are undergoing DNA replication that incorporate radionucleosides into their chromosomes. | 06-09-2011 |
Patent application number | Description | Published |
20120330532 | Method Of Adjusting A Fuel Composition Estimate - A method is provided for adjusting a fuel composition estimate. The method generally uses a non-fuel related property to determine fuel composition. In some cases the method can be used after refueling and when the engine is operating without the benefit of oxygen sensor data, which can include evaluating data not based on characteristics of the fuel or exhaust from its combustion, such as engine torque variations while using the fuel. The method can include monitoring estimated engine torque to determine whether first variations in engine torque exceed a threshold, and, if so, modifying the previous estimate of fuel composition prior to the refueling event by a pre-determined amount. | 12-27-2012 |
20130055798 | Method Of Controlling Fuel Composition Learning - A method of controlling fuel composition learning includes steps of monitoring changes in airflow within an engine to determine steady state conditions. The method further includes steps of initiating a fuel composition learning process during steady state conditions. A current fuel component concentration factor is updated using a temporary fuel component concentration factor. The temporary fuel component concentration factor is calculated as the average of an air/fuel correction factor. Once the current fuel component concentration factor is updated, the temporary fuel component concentration factor is reset. The air/fuel correction factor is reset to reflect any difference that existed between the temporary fuel component concentration factor and the air/fuel correction factor at the update time. | 03-07-2013 |
20130298653 | Method Of Controlling Fuel Composition Learning - A method of controlling fuel composition learning includes steps of monitoring changes in airflow within an engine to determine steady state conditions. The method further includes steps of initiating a fuel composition learning process during steady state conditions. A current fuel component concentration factor is updated using a temporary fuel component concentration factor. The temporary fuel component concentration factor is calculated as the average of an air/fuel correction factor. Once the current fuel component concentration factor is updated, the temporary fuel component concentration factor is reset. The air/fuel correction factor is reset to reflect any difference that existed between the temporary fuel component concentration factor and the air/fuel correction factor at the update time. | 11-14-2013 |
20140044149 | VEHICLE AMBIENT TEMPERATURE ESTIMATION SYSTEM - Ambient temperature is determined using a vehicle-implemented system based on an estimated ambient temperature determined in view of a radiator fluid temperature profile. During periods of radiator fan operation, radiator fluid temperature is measured and logged to create the radiator fluid temperature profile. A best-fit polynomial is fitted to the radiator fluid temperature profile, and a coefficient from the best-fit polynomial is used to reference a best-fit equation to ambient temperature relation. The relation is predetermined for the particular vehicle configuration, and the ambient temperature is estimated based on the coefficient from the fitted best-fit polynomial. | 02-13-2014 |