Markworth, US
Aaron Markworth, New York, NY US
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20110046684 | Screw Assembly and Method - A screw assembly and method includes a coupling member comprising a semi-bulbous end; a fixator component that receives the semi-bulbous end of the coupling member; a resisting member mounted in the coupling member and comprising a mating member; a connection pin comprising a resisting member socket operatively connected to the mating member of the resisting member; and a blocker that engages the coupling member. | 02-24-2011 |
Aaron Markworth, Saddle Brook, NJ US
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20090036987 | ARTIFICIAL INTERVERTEBRAL DISC - An artificial intervertebral disc and method of attaching the disc to vertebral bodies includes a plurality of separate structural members arranged in a stacked configuration, wherein each structural member comprises a female cavity having a unique size compared with the female cavities of the other structural members, wherein a top and middle structural member comprise male bodies defined by outer edges of the respective female cavities of the top and middle structural members, wherein the male body of the top structural member is dimensioned and configured to sit in the female body of the middle structural member, wherein the male body of the middle structural member is dimensioned and configured to sit in the female body of a bottom structural member, and wherein each of the top and bottom structural member comprise at least one projecting member outwardly extending therefrom. | 02-05-2009 |
Aaron Markworth, Pompton Lakes, NJ US
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20130317551 | METHODS FOR STABILIZING BONE USING SPINAL FIXATION DEVICES - In one embodiment, the present invention includes a method of stabilizing a spine including providing a coupling element having an uppermost end defining a first plane, a lowermost end defining a second plane, and at least one bore extending from said uppermost end toward said lowermost end, wherein said first and second planes intersect one another, assembling said coupling element with an anchoring element, and after the assembling step, securing said anchoring element in bone. | 11-28-2013 |
20150032160 | STABILIZING BONE USING SPINAL FIXATION DEVICES AND SYSTEMS - In one embodiment, the present invention includes a bone fixation assembly comprising a coupling element and a bone anchor. The coupling element has an upper surface with a first diameter defining a first bore extending along a first axis, a lower surface with a second diameter defining a second bore extending along a second axis, and an internal surface area defining a seating portion adjacent to the lower surface. The bone anchor has an insertion end opposite of a head. The head may be curved for receipt within the seating portion. The second diameter of the second bore may be greater than the first diameter of the first bore or vice versa. Likewise, the first and second axes may intersect such that the first and second bores are in communication with one another. Related elements and systems of this assembly are also disclosed. | 01-29-2015 |
Aaron Markworth, Flanders, NJ US
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20140330280 | INTERBODY DISTRACTOR - An interbody distractor and geometry trial instrument to measure a height and an angle for an associated implant includes a height handle and an expansion head coupled to the height handle that is adapted to be positioned in a vertebral body. A wedge sleeve is coupled to the expansion head, to control an angle of a first surface plate and a second surface plate of the expansion head when the wedge sleeve interacts with the expansion head. A wedge sleeve knob is adapted to drive the wedge sleeve linearly towards the vertebral body when the wedge sleeve knob is actuated. A height of the expansion head and an angle of the first and the second surface plate are measured to determine the height and the angle of the associated implant when the height handle and the wedge sleeve knob are actuated. | 11-06-2014 |
Aaron D. Markworth, New York, NY US
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20120010618 | Anterior Cervical Plate with Independent Spring-Loaded Locking Slides for Each Screw - An anterior cervical plate and method includes a plurality of retaining slots comprising a first and second hole each adapted to permit bone retaining members to pass partially therethrough; and a platform separating the first hole from the second hole. The plate further comprises a pair of locking slides matingly adjacent to one another and adapted to rest on the platform and retain the bone retaining members in the plurality of retaining slots, wherein each the locking slide comprises a deflectable flange; and a lip positioned on an opposite side of the deflectable flange, wherein a first locking slide of the pair of locking slides is positioned in an opposite orientation relative to a second locking slide of the pair of locking slides. The deflectable flange of the first locking slide is aligned adjacent to the deflectable flange of the second locking slide. | 01-12-2012 |
Aaron D. Markworth, Saddle Creek, NJ US
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20100076494 | PEDICLE SCREW ASSEMBLY - A medical device and methods of use thereof are provided for supporting a structure (e.g., bone). A screw assembly is provided that is comprised of a base, an arm, and an interconnection means for coupling the base to the arm. The interconnection means allows the arm to be positionable in a first position that is parallel to a long axis of the base and positionable in a second position that is perpendicular to the long axis of the base. The base is configured for attachment to a structure and the arm configured for attachment to a support structure. A support structure is provided that includes one or more receivers having locking means, which can be configured as an open-ended saddle for attachment to a medical device (e.g., a screw assembly). The support structure is configured to receive one or more medical devices and lock the medical devices to the support structure after installation in a patient. | 03-25-2010 |
Aaron D. Markworth, Saddle Brook, NJ US
Patent application number | Description | Published |
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20080287999 | ANTERIOR CERVICAL PLATE WITH INDEPENDENT SPRING-LOADED LOCKING SLIDES FOR EACH SCREW - An anterior cervical plate and method includes a plurality of retaining slots comprising a first and second hole each adapted to permit bone retaining members to pass partially therethrough; and a platform separating the first hole from the second hole. The plate further comprises a pair of locking slides matingly adjacent to one another and adapted to rest on the platform and retain the bone retaining members in the plurality of retaining slots, wherein each the locking slide comprises a deflectable flange; and a lip positioned on an opposite side of the deflectable flange, wherein a first locking slide of the pair of locking slides is positioned in an opposite orientation relative to a second locking slide of the pair of locking slides. The deflectable flange of the first locking slide is aligned adjacent to the deflectable flange of the second locking slide. | 11-20-2008 |
20100070034 | CERVICAL INTRA-LAMINA FUSION IMPLANT DEVICE AND METHOD - A cervical intra-laminar fusion implant to be placed in cervical lamina includes a first lateral surface including a first arched edge, a second lateral surface positioned opposite to the first lateral surface, the second lateral surface including a plurality of posterior windows and a second arched edge, a top wall attached to the first lateral surface and the second lateral surface, the top wall having a plurality of teeth, a bottom wall positioned opposite to the top wall and attached to the first lateral surface and the second lateral surface, the bottom wall having a plurality of bottom teeth, a plurality of internal voids configured through the top wall and the bottom wall, and a connection mechanism connected to the top wall. The connection mechanism is positioned superior over the cervical lamina. | 03-18-2010 |
20100137988 | Compliant Interbody Fusion Device With Deployable Bone Anchors - An interbody fusion implant with deployable bone anchors includes a support member, a monolithic body that accommodates the support member, and a longitudinal hole along a vertical length of the support member. The support member includes a first end and a second end. The second end includes two flanges. The flanges are configured to dig into an endplate of a vertebral body. The flanges of the support member provide a location fixation on an implantation of the interbody fusion implant into the vertebral body. The support member may also include at least one of a clip shaped support member and an I-shaped support member. The I-shaped support member may allow a rigidity and a support in flexion-extension through a living-hinge positioned in a middle of the I-shaped support member. The longitudinal hole sustains loads imported on the interbody fusion implant and allows the interbody fusion implant to flex freely. | 06-03-2010 |
20100161058 | Multiple-State Geometry Artificial Disc With Compliant Insert and Method - A multiple-state geometry artificial disc assembly attached to vertebrae includes a compliant load bearing spacer element having an upper curved portion and a lower curved portion, a first plate coupled on the upper curved portion of the compliant load bearing spacer element and a second plate coupled on the lower curved portion of the compliant load bearing spacer element. The first plate and the second plate preferably are of a flexible material. The first plate and the second plate transitions from a convex configuration to a concave configuration in-situ in a vertebral disc space. The upper curved portion and the lower curved portion of the compliant load bearing spacer element may include a plurality of openings. The compliant load bearing spacer element may further include a middle cylindrical portion dimensioned and configured to match a gap between the first plate and the second plate. | 06-24-2010 |
20120029644 | Compliant Interbody Fusion Device with Deployable Bone Anchors - An interbody fusion implant with deployable bone anchors includes a support member, a monolithic body that accommodates the support member, and a longitudinal hole along a vertical length of the support member. The support member includes a first end and a second end. The second end includes two flanges. The flanges are configured to dig into an endplate of a vertebral body. The flanges of the support member provide a location fixation on an implantation of the interbody fusion implant into the vertebral body. The support member may also include at least one of a clip shaped support member and an I-shaped support member. The I-shaped support member may allow a rigidity and a support in flexion-extension through a living-hinge positioned in a middle of the I-shaped support member. The longitudinal hole sustains loads imported on the interbody fusion implant and allows the interbody fusion implant to flex freely. | 02-02-2012 |
Alan J. Markworth, Columbus, OH US
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20100092816 | METHODS OF REMOVING CONTAMINANTS FROM A FUEL CELL ELECTRODE - A method of optimizing a waveform of an electrical current applied to an electrode includes the steps of: applying an electrical current to an electrode of a device; determining a waveform of the voltage or the current of the electrical current; representing the waveform by a mathematical description such as a number of points or an analytical function characterized by a number of unknown coefficients and a fixed number of known functions; measuring a function of the device associated with the application of the electrical current; feeding the waveform description and the measurements to an algorithm, which may be in a computer program or other calculating device including manual calculations, including an optimization routine which uses the points or coefficients as independent variables for optimizing the function of the device; and performing the calculations to determine values of the points or coefficients which optimize the function of the device, and thereby determine an optimized waveform of the electrical current to be applied to the electrode of the device. | 04-15-2010 |
Caroline M. Markworth, Columbus, OH US
Patent application number | Description | Published |
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20100092816 | METHODS OF REMOVING CONTAMINANTS FROM A FUEL CELL ELECTRODE - A method of optimizing a waveform of an electrical current applied to an electrode includes the steps of: applying an electrical current to an electrode of a device; determining a waveform of the voltage or the current of the electrical current; representing the waveform by a mathematical description such as a number of points or an analytical function characterized by a number of unknown coefficients and a fixed number of known functions; measuring a function of the device associated with the application of the electrical current; feeding the waveform description and the measurements to an algorithm, which may be in a computer program or other calculating device including manual calculations, including an optimization routine which uses the points or coefficients as independent variables for optimizing the function of the device; and performing the calculations to determine values of the points or coefficients which optimize the function of the device, and thereby determine an optimized waveform of the electrical current to be applied to the electrode of the device. | 04-15-2010 |
Christopher J. Markworth, Durham, NC US
Patent application number | Description | Published |
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20080269204 | Compounds and Methods of Use Thereof - Benzolactam boronic acid compounds and pharmaceutical formulations are described along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 10-30-2008 |
20080319044 | Compounds and Methods of Use Thereof - Indole boronic acid compounds, and analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 12-25-2008 |
20090005344 | Compounds and Methods of Use Thereof - Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 01-01-2009 |
20090264384 | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF - Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof. | 10-22-2009 |
Christopher John Markworth, Durham, NC US
Patent application number | Description | Published |
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20090023740 | SODIUM CHANNEL INHIBITORS - Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel. | 01-22-2009 |
20090143358 | INHIBITORS OF ION CHANNELS - Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel. | 06-04-2009 |
20100197655 | SULFONAMIDE DERIVATIVES - The present invention relates to compounds of the formula | 08-05-2010 |
20120149679 | Sulfonamide Derivatives - The present invention relates to compounds of the formula | 06-14-2012 |
20130072471 | Inhibitors of Ion Channels - Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel. | 03-21-2013 |
20130109667 | Chemical Compounds | 05-02-2013 |
20130338111 | Sulfonamide Derivatives - The present invention relates to compounds of the formula | 12-19-2013 |
Thomas C. Markworth, San Carlos, CA US
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20130262431 | Method and Apparatus for Identifying and Recommending Content - A method for matching a search request from a client device includes detecting the search request from the client device, storing content listings within a content database where each of the content listings represents content, and searching for a match result between the search request and the content listings. A subscription to a subscribed content provider is detected and associated with the client device. The match result is displayed to indicate the content listings associated with the subscribed content provider. | 10-03-2013 |
20130262997 | Method and Apparatus for Displaying Information on a Secondary Screen - A method of coordinating a primary display device and a secondary display device includes transmitting a representation of a content selection to a client device. A selection of the content selection is detected by the client device. An augmented view of the content selection is transmitted to a secondary display device in response to the selection of the content selection. A response from the secondary display device is detected based on the augmented view of the content selection. The augmented view of the content selection is updated based upon the response. | 10-03-2013 |